adenine has been researched along with Lymphoma in 54 studies
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
Excerpt | Relevance | Reference |
---|---|---|
"2-Amino-N6-hydroxyadenine (AHA) was tested in the mouse lymphoma L5178Y tk +/- assay using the microtitre cloning technique over concentrations from 0." | 7.68 | The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk +/- 3.7.2C mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei. ( Bridges, BA; Cole, J; Richmond, FN, 1991) |
"2-Amino-N6-hydroxyadenine (AHA) was tested in the mouse lymphoma L5178Y tk +/- assay using the microtitre cloning technique over concentrations from 0." | 3.68 | The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk +/- 3.7.2C mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei. ( Bridges, BA; Cole, J; Richmond, FN, 1991) |
"Twenty-six patients with advanced cancer underwent acetylator phenotyping with caffeine and were assigned to a dose level." | 2.67 | Phase I study of amonafide dosing based on acetylator phenotype. ( Berezin, F; Janisch, L; Lane, LB; Mick, R; Ratain, MJ; Schilsky, RL; Vogelzang, NJ, 1993) |
" Here side effects of ibrutinib have been summarized and important considerations in the management of these adverse events have been reviewed." | 2.61 | Management of adverse effects/toxicity of ibrutinib. ( Paydas, S, 2019) |
" KIN-8194 demonstrated excellent bioavailability and pharmacokinetic parameters, with good tolerance in rodent models at pharmacologically achievable and active doses." | 1.62 | The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance. ( Anderson, KC; Buhrlage, SJ; Cameron, M; Castillo, JJ; Che, J; Chen, JG; Demos, MG; Gray, NS; Guerrera, ML; Hunter, ZR; Kofides, A; Liu, X; Meid, K; Munshi, M; Munshi, NC; Patterson, CJ; Tan, L; Treon, SP; Tsakmaklis, N; Wang, J; Xu, L; Yang, G, 2021) |
"Increased aspergillosis was observed with ibrutinib monotherapy and DA-TEDDi-R." | 1.46 | Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma. ( Bhaumik, S; Butman, JA; Ceribelli, M; Chen, L; Cole, DE; Desai, JV; Dunleavy, K; Gea-Banacloche, J; Heiss, J; Higham, CS; Jaffe, ES; Lionakis, MS; Little, RF; Lucas, N; Melani, C; Pittaluga, S; Roschewski, M; Schmitz, R; Staudt, LM; Steinberg, SM; Stetler-Stevenson, M; Thomas, CJ; Widemann, BC; Wilson, WH; Yang, Y, 2017) |
"We report a case of autoimmune thrombocytopenia associated with acute reverse seroconversion of hepatitis B in a patient who was initially hepatitis B virus surface antigen negative and hepatitis B virus surface antibody positive." | 1.34 | [Autoimmune thrombopenia associated with hepatitis B reactivation (reverse seroconversion) after autologous hematopoietic stem cell transplantation]. ( Aubourg, A; Bacq, Y; d'Alteroche, L; Gaudy, C; Senecal, D, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (31.48) | 18.7374 |
1990's | 6 (11.11) | 18.2507 |
2000's | 4 (7.41) | 29.6817 |
2010's | 16 (29.63) | 24.3611 |
2020's | 11 (20.37) | 2.80 |
Authors | Studies |
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Malfona, F | 1 |
Testi, AM | 1 |
Moleti, ML | 1 |
Petrucci, L | 1 |
Leccisotti, L | 1 |
Martelli, M | 1 |
Di Rocco, A | 1 |
Jimenez, JE | 1 |
Dai, D | 1 |
Xu, G | 1 |
Zhao, R | 1 |
Li, T | 1 |
Pan, T | 1 |
Wang, L | 1 |
Lin, Y | 1 |
Wang, Z | 1 |
Jaffray, D | 1 |
Hazle, JD | 1 |
Macapinlac, HA | 1 |
Wu, J | 1 |
Lu, Y | 1 |
Grainger, BT | 1 |
Issa, S | 2 |
Lauer, EM | 1 |
Waterhouse, M | 1 |
Braig, M | 1 |
Mutter, J | 1 |
Bleul, S | 1 |
Duque-Afonso, J | 1 |
Duyster, J | 1 |
Marks, R | 1 |
Reinacher, PC | 1 |
Prinz, M | 1 |
Illerhaus, G | 1 |
Finke, J | 1 |
Schorb, E | 1 |
Scherer, F | 1 |
Lewis, KL | 1 |
Chin, CK | 1 |
Manos, K | 1 |
Casey, J | 1 |
Hamad, N | 1 |
Crawford, J | 1 |
Ho, SJ | 1 |
Grigg, A | 1 |
Wood, P | 1 |
Gandhi, MK | 1 |
Do, B | 1 |
Nastoupil, L | 1 |
Hawkes, EA | 1 |
Cheah, CY | 1 |
Chen, F | 1 |
Pang, D | 1 |
Guo, H | 1 |
Ou, Q | 1 |
Wu, X | 1 |
Jiang, X | 1 |
Wei, X | 1 |
Liu, S | 1 |
Huang, L | 1 |
Liang, Z | 1 |
Zhou, D | 1 |
Li, W | 1 |
Meitlis, I | 1 |
Allenspach, EJ | 1 |
Bauman, BM | 1 |
Phan, IQ | 1 |
Dabbah, G | 1 |
Schmitt, EG | 1 |
Camp, ND | 1 |
Torgerson, TR | 1 |
Nickerson, DA | 1 |
Bamshad, MJ | 1 |
Hagin, D | 1 |
Luthers, CR | 1 |
Stinson, JR | 1 |
Gray, J | 1 |
Lundgren, I | 1 |
Church, JA | 1 |
Butte, MJ | 1 |
Jordan, MB | 1 |
Aceves, SS | 1 |
Schwartz, DM | 1 |
Milner, JD | 1 |
Schuval, S | 1 |
Skoda-Smith, S | 1 |
Cooper, MA | 1 |
Starita, LM | 1 |
Rawlings, DJ | 1 |
Snow, AL | 1 |
James, RG | 1 |
Claves, F | 1 |
Siest, R | 1 |
Lefebvre, C | 1 |
Valmary-Degano, S | 1 |
Carras, S | 1 |
Yang, G | 1 |
Wang, J | 1 |
Tan, L | 1 |
Munshi, M | 1 |
Liu, X | 1 |
Kofides, A | 1 |
Chen, JG | 1 |
Tsakmaklis, N | 1 |
Demos, MG | 1 |
Guerrera, ML | 1 |
Xu, L | 1 |
Hunter, ZR | 1 |
Che, J | 1 |
Patterson, CJ | 1 |
Meid, K | 1 |
Castillo, JJ | 1 |
Munshi, NC | 1 |
Anderson, KC | 1 |
Cameron, M | 1 |
Buhrlage, SJ | 1 |
Gray, NS | 1 |
Treon, SP | 1 |
Gángó, A | 1 |
Kiss, R | 1 |
Farkas, P | 1 |
Hanna, E | 1 |
Demeter, J | 1 |
Deák, B | 1 |
Lévai, D | 1 |
Kotmayer, L | 1 |
Alpár, D | 1 |
Matolcsy, A | 1 |
Bödör, C | 1 |
Mátrai, Z | 1 |
Timár, B | 1 |
Feldman, RC | 1 |
Hyman, DA | 1 |
Price, WN | 1 |
Ratain, MJ | 2 |
Lionakis, MS | 1 |
Dunleavy, K | 1 |
Roschewski, M | 1 |
Widemann, BC | 1 |
Butman, JA | 1 |
Schmitz, R | 1 |
Yang, Y | 1 |
Cole, DE | 1 |
Melani, C | 1 |
Higham, CS | 1 |
Desai, JV | 1 |
Ceribelli, M | 1 |
Chen, L | 1 |
Thomas, CJ | 1 |
Little, RF | 1 |
Gea-Banacloche, J | 1 |
Bhaumik, S | 1 |
Stetler-Stevenson, M | 1 |
Pittaluga, S | 1 |
Jaffe, ES | 1 |
Heiss, J | 1 |
Lucas, N | 1 |
Steinberg, SM | 1 |
Staudt, LM | 1 |
Wilson, WH | 1 |
Guha, A | 1 |
Derbala, MH | 1 |
Zhao, Q | 1 |
Wiczer, TE | 1 |
Woyach, JA | 1 |
Byrd, JC | 1 |
Awan, FT | 1 |
Addison, D | 1 |
Grommes, C | 1 |
Tang, SS | 1 |
Wolfe, J | 1 |
Kaley, TJ | 1 |
Daras, M | 1 |
Pentsova, EI | 1 |
Piotrowski, AF | 1 |
Stone, J | 1 |
Lin, A | 1 |
Nolan, CP | 1 |
Manne, M | 1 |
Codega, P | 1 |
Campos, C | 1 |
Viale, A | 1 |
Thomas, AA | 1 |
Berger, MF | 1 |
Hatzoglou, V | 1 |
Reiner, AS | 1 |
Panageas, KS | 1 |
DeAngelis, LM | 1 |
Mellinghoff, IK | 1 |
Tarantelli, C | 1 |
Gaudio, E | 1 |
Cascione, L | 1 |
Stathis, A | 1 |
Zucca, E | 1 |
Bertoni, F | 1 |
Paydas, S | 1 |
Soussain, C | 2 |
Choquet, S | 2 |
Blonski, M | 1 |
Leclercq, D | 1 |
Houillier, C | 2 |
Rezai, K | 1 |
Bijou, F | 1 |
Houot, R | 1 |
Boyle, E | 2 |
Gressin, R | 1 |
Nicolas-Virelizier, E | 1 |
Barrie, M | 1 |
Moluçon-Chabrot, C | 1 |
Lelez, ML | 1 |
Clavert, A | 1 |
Coisy, S | 1 |
Leruez, S | 1 |
Touitou, V | 1 |
Cassoux, N | 1 |
Daniau, M | 1 |
Ertault de la Bretonnière, M | 1 |
El Yamani, A | 1 |
Ghesquières, H | 1 |
Hoang-Xuan, K | 2 |
Vargas, L | 1 |
Hamasy, A | 1 |
Nore, BF | 1 |
Smith, CI | 1 |
Turetsky, A | 1 |
Kim, E | 1 |
Kohler, RH | 1 |
Miller, MA | 1 |
Weissleder, R | 1 |
Sagiv-Barfi, I | 1 |
Kohrt, HE | 1 |
Burckhardt, L | 1 |
Czerwinski, DK | 1 |
Levy, R | 1 |
Grisafi, D | 1 |
Maestro, A | 1 |
Grumi, C | 1 |
Piazzoni, L | 1 |
Tirone, G | 1 |
Fiore, W | 1 |
Tessari, R | 1 |
Gianardi, V | 1 |
Gatti, M | 1 |
Tasca, F | 1 |
Generali, D | 1 |
Ravelli, A | 1 |
Lanza, F | 1 |
Scaglione, F | 1 |
Iida, S | 1 |
Cheson, BD | 1 |
Leong, DP | 1 |
Caron, F | 1 |
Hillis, C | 1 |
Duan, A | 1 |
Healey, JS | 1 |
Fraser, G | 1 |
Siegal, D | 1 |
Cai, Q | 1 |
Chen, K | 1 |
Chen, J | 1 |
Wu, S | 1 |
Geng, Q | 1 |
Huang, H | 1 |
Lin, T | 1 |
Jiang, W | 1 |
Xia, Z | 1 |
Duan, H | 1 |
Rao, H | 1 |
Yao, M | 1 |
Hu, L | 1 |
Chamoun, K | 1 |
Larrieu-Ciron, D | 1 |
Al Jijakli, A | 1 |
Delrieu, V | 1 |
Delwail, V | 1 |
Morschhauser, F | 1 |
Feeney, SA | 1 |
McCaughey, C | 1 |
Watt, AP | 1 |
Agnaf, MR | 1 |
McDougall, N | 1 |
Wend, UC | 1 |
Gerlich, WH | 1 |
Coyle, PV | 1 |
SARTORELLI, AC | 4 |
UPCHURCH, HF | 1 |
BIEBER, AL | 1 |
CHANG, PK | 1 |
FISCHER, GA | 1 |
Goursaud, S | 1 |
Pineau, N | 1 |
Becq-Giraudon, L | 1 |
Gressens, P | 1 |
Muller, JM | 1 |
Janet, T | 1 |
Sharif, FA | 1 |
Yilmaz, Y | 1 |
Zieske, A | 1 |
Qumsiyeh, MB | 1 |
Aubourg, A | 1 |
d'Alteroche, L | 1 |
Senecal, D | 1 |
Gaudy, C | 1 |
Bacq, Y | 1 |
Zápotocký, M | 1 |
Hanzalová, J | 1 |
Starková, J | 1 |
Votruba, I | 1 |
Holý, A | 1 |
Otová, B | 1 |
Nguyen, BT | 1 |
El Sayed, YM | 1 |
Sadée, W | 2 |
Buchwald, M | 1 |
Ullman, B | 4 |
Martin, DW | 1 |
Makukho, LV | 1 |
Volkolupova, OP | 1 |
Mick, R | 1 |
Berezin, F | 1 |
Janisch, L | 1 |
Schilsky, RL | 1 |
Vogelzang, NJ | 1 |
Lane, LB | 1 |
Morgan, AJ | 1 |
Murray, KJ | 1 |
Challiss, RA | 1 |
Clive, D | 1 |
Glover, P | 1 |
Krehl, R | 1 |
Poorman-Allen, P | 1 |
Evans, HH | 1 |
Mencl, J | 1 |
Ricanati, M | 1 |
DiSalvo, C | 1 |
Varnes, ME | 1 |
Cole, J | 1 |
Richmond, FN | 1 |
Bridges, BA | 1 |
Hanson, S | 2 |
McCartan, K | 1 |
Sabina, RL | 1 |
Holmes, EW | 1 |
Beck, J | 1 |
Duan, DS | 1 |
Plagemann, PG | 1 |
Wohlhueter, RM | 1 |
Adamson, RH | 1 |
Ablashi, DV | 1 |
Cicmanec, JL | 1 |
Dalgard, DW | 1 |
Tyrsted, G | 1 |
Warnick, CT | 1 |
Kim, SC | 1 |
Paterson, AR | 1 |
Fuska, J | 1 |
Ivanitskaya, L | 1 |
Horáková, K | 1 |
Kuhr, I | 1 |
Frei, JV | 1 |
Robins, AB | 1 |
Taylor, DM | 1 |
Mandel, LR | 1 |
Srinivasan, PR | 1 |
Borek, E | 1 |
Tsunamura, S | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Clinical Efficacy and Safety of IBER Salvage Treatment Followed by Ibrutinib Maintenance for Transplant-ineligible Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL): a Multicenter, Single-arm, Prospective Phase II Study[NCT04066920] | Phase 2 | 30 participants (Anticipated) | Interventional | 2019-10-01 | Not yet recruiting | ||
Implanted Loop Recorders (ILR) for the Detection and Management of Arrhythmia in Patients Treated With Bruton Tyrosine Kinase (BTK) Inhibitors[NCT05643235] | 50 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
A Phase I/II Trial of the Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Patients With Newly Diagnosed or Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCN[NCT02315326] | Phase 1/Phase 2 | 109 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | ||
Phase II Study of Ibrutinib in Patients With Relapsed or Refractory Primary Central Nervous Lymphoma or Intraocular Lymphoma[NCT02542514] | Phase 2 | 52 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
Long-term Effect of Chronic Ibrutinib Therapy on Left Atrial Function[NCT03751410] | 40 participants (Actual) | Observational [Patient Registry] | 2018-12-01 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
7 reviews available for adenine and Lymphoma
Article | Year |
---|---|
Bing-Neel syndrome presenting as isolated CNS lymphoplasmacytic lymphoma: A case report and review of the literature.
Topics: Adenine; Female; Humans; Lymphoma; Meningeal Carcinomatosis; Middle Aged; Piperidines; Pyrazoles; Py | 2020 |
Management of adverse effects/toxicity of ibrutinib.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Atrial Fibrillation; Drug-Related Side Effects and Adv | 2019 |
Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Agammaglobulinemia; Antineoplastic Agents; Autoimmunit | 2013 |
Ibrutinib: from bench side to clinical implications.
Topics: Adenine; Antineoplastic Agents; Biomedical Research; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; | 2015 |
Overview: A New Era of Cancer Genomics in Lymphoid Malignancies.
Topics: Adenine; Antineoplastic Agents; Biomarkers, Tumor; Clinical Trials as Topic; Genome, Human; Genomics | 2015 |
Speed bumps on the road to a chemotherapy-free world for lymphoma patients.
Topics: Adenine; Clinical Trials as Topic; Drug Design; Humans; Lymphoma; Piperidines; Purines; Pyrazoles; P | 2016 |
The risk of atrial fibrillation with ibrutinib use: a systematic review and meta-analysis.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Atrial Fibrillation; Humans; Incidence; Leuke | 2016 |
4 trials available for adenine and Lymphoma
Article | Year |
---|---|
Ibrutinib for central nervous system lymphoma: the Australasian Lymphoma Alliance/MD Anderson Cancer Center experience.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Disease-Free Survival; Fe | 2021 |
Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma.
Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Antineoplastic Agents; Antineoplastic Com | 2019 |
Ibrutinib monotherapy for relapse or refractory primary CNS lymphoma and primary vitreoretinal lymphoma: Final analysis of the phase II 'proof-of-concept' iLOC study by the Lymphoma study association (LYSA) and the French oculo-cerebral lymphoma (LOC) net
Topics: Adenine; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Drug Resistance, Neoplasm; Femal | 2019 |
Phase I study of amonafide dosing based on acetylator phenotype.
Topics: Acetylation; Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; | 1993 |
43 other studies available for adenine and Lymphoma
Article | Year |
---|---|
Efficacy of ibrutinib as salvage treatment in a secondary central nervous system lymphoma (SCNSL) progressed after chemorefractory Primary Mediastinal B Cell Lymphoma (PMBCL).
Topics: Adenine; Central Nervous System; Central Nervous System Neoplasms; Humans; Lymphoma; Lymphoma, B-Cel | 2022 |
Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma.
Topics: Adenine; Fluorodeoxyglucose F18; Humans; Lymphoma; Piperidines; Positron Emission Tomography Compute | 2022 |
Ibrutinib in patients with relapsed/refractory central nervous system lymphoma: A retrospective single-centre analysis.
Topics: Adenine; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Male; | 2020 |
Clinical outcomes of newly diagnosed primary CNS lymphoma treated with ibrutinib-based combination therapy: A real-world experience of off-label ibrutinib use.
Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Antineoplastic Combined Chemotherapy Prot | 2020 |
Multiplexed Functional Assessment of Genetic Variants in CARD11.
Topics: Adenine; B-Cell CLL-Lymphoma 10 Protein; B-Lymphocytes; CARD Signaling Adaptor Proteins; Cell Line; | 2020 |
Dramatic Efficacy of Ibrutinib in a Schnitzler Syndrome Case with Indolent Lymphoma.
Topics: Adenine; Female; Humans; Interleukin-1; Lymphoma; Middle Aged; Piperidines; Schnitzler Syndrome | 2021 |
The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug | 2021 |
Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax.
Topics: Adenine; Adult; Aged; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Female; Genes, | 2022 |
Negative innovation: when patents are bad for patients.
Topics: Adenine; Antineoplastic Agents; Humans; Leukemia; Lymphoma; Patents as Topic; Patient Harm; Piperidi | 2021 |
Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Animals; Aspergillosis; Brain | 2017 |
Ventricular Arrhythmias Following Ibrutinib Initiation for Lymphoid Malignancies.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Cohort Studies; Female; Follow-Up Studies; Human | 2018 |
In vitro demonstration of synergism with pixantrone combined with targeted agents in lymphomas.
Topics: Adenine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Huma | 2019 |
Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Binding Sites; Cell Line, Tumor; Gene Express | 2014 |
Ibrutinib enhances the antitumor immune response induced by intratumoral injection of a TLR9 ligand in mouse lymphoma.
Topics: Adenine; Adjuvants, Immunologic; Animals; Cell Line; Drug Synergism; Female; Injections, Intralesion | 2015 |
The Effect of Prophylactic Lamivudine plus Adefovir Therapy Compared with Lamivudine Alone in Preventing Hepatitis B Reactivation in Lymphoma Patients with High Baseline HBV DNA during Chemotherapy.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; DNA, Viral; Drug Inter | 2016 |
Ibrutinib monotherapy in relapsed/refractory CNS lymphoma: A retrospective case series.
Topics: Adenine; Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Female; Follow-Up Studies; H | 2017 |
Reactivation of occult hepatitis B virus infection following cytotoxic lymphoma therapy in an anti-HBc negative patient.
Topics: Adenine; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antiviral Agents; DNA, | 2013 |
PHYSIOLOGICAL DISPOSITION AND THERAPEUTIC CONSEQUENCES OF ADENINE ADMINISTERED VIA THE GASTROINTESTINAL TRACT IN NORMAL AND TUMOR-BEARING MICE.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatoc | 1963 |
SOME INHIBITORY PROPERTIES OF 6-N-HYDROXYLAMINOPURINE: AN ANALOG OF ADENINE AND HYPOXANTHINE.
Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Glycine; Guanine Nucleotide | 1964 |
Human H9 cells proliferation is differently controlled by vasoactive intestinal peptide or peptide histidine methionine: implication of a GTP-insensitive form of VPAC1 receptor.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Analysis of Variance; Blotting, Southern; Bromodeoxyuridine; C | 2005 |
Natural killer cell lymphoma/leukemia with homozygous loss of p27/kip1.
Topics: Adenine; Aged; Amino Acid Sequence; Base Sequence; Cyclin-Dependent Kinase Inhibitor p27; Cytogeneti | 2005 |
[Autoimmune thrombopenia associated with hepatitis B reactivation (reverse seroconversion) after autologous hematopoietic stem cell transplantation].
Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Hematopoietic Stem Cell T | 2007 |
Experimental therapy with 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): origin of resistance.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expressio | 2007 |
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells.
Topics: Adenine; Adenosine; Alanine; Animals; Antimetabolites, Antineoplastic; Cell Division; DNA Replicatio | 1984 |
Biochemical and genetic analysis of AMP deaminase deficiency in cultured mammalian cells.
Topics: Adenine; AMP Deaminase; Animals; Cell Division; Cell Line; Guanosine Triphosphate; Kinetics; Lymphom | 1981 |
[Use of an express method in studying the cytotoxic action of antitumor antibiotics].
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Carbon Radioisotopes; Cells, Cultured; Drug Evaluatio | 1981 |
Comparison of methods to assess cyclic AMP turnover under conditions of agonist stimulation in 1321N1 astrocytoma cells.
Topics: Adenine; Adenosine Triphosphate; Animals; Astrocytoma; Carbon Radioisotopes; Cell Line; Cyclic AMP; | 1992 |
Mutagenicity of 2-amino-N6-hydroxyadenine (AHA) at three loci in L5178Y/tk+/- mouse lymphoma cells: molecular and preliminary cytogenetic characterizations of AHA-induced tk-/- mutants.
Topics: Adenine; Animals; Blotting, Southern; Cell Survival; Chromosome Banding; Hypoxanthine Phosphoribosyl | 1991 |
Mutagenicity of 2-amino-N6-hydroxyadenine at the tk locus in L5178Y strains differing in repair capabilities and karyotype.
Topics: Adenine; Animals; Cell Survival; DNA Damage; DNA Repair; Free Radicals; Lymphoma; Mice; Mutagenicity | 1991 |
The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk +/- 3.7.2C mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei.
Topics: Adenine; Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Lymphoma; Mice; | 1991 |
Adenylate deaminase deficiency in a mutant murine T cell lymphoma cell line.
Topics: Adenine; AMP Deaminase; Animals; Blotting, Southern; Cell Division; Cell Line; Cell Survival; DNA, N | 1990 |
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug; | 1989 |
AMP deaminase and thymidine kinase deficiencies in a mutant mouse S49 cell clone.
Topics: Adenine; AMP Deaminase; Animals; Cell Division; Clone Cells; Dose-Response Relationship, Drug; Hybri | 1989 |
Distinct effects of adenine and guanine starvation on DNA synthesis associated with different pool sizes of nucleotide precursors.
Topics: Adenine; Animals; Cell Compartmentation; Cell Cycle; Cell Line; Deoxyadenosines; DNA Replication; DN | 1987 |
S49 mouse lymphoma cells are deficient in hypoxanthine transport.
Topics: Adenine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Hypoxanthin | 1986 |
Chemotherapy of Herpesvirus saimiri induced lymphoma-leukemia in the owl monkey.
Topics: Adenine; Animals; Arabinose; Cyclophosphamide; Cytarabine; Disease Models, Animal; Haplorhini; Herpe | 1974 |
Inhibition of the synthesis of 5-phosphoribosyl-1-pyrophosphate by 3'-deoxy-adenosine and structurally related nucleoside analogs.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Diphosphates; Glucose; Glucosyltransfer | 1968 |
Inhibition of purine synthesis de novo in cultured L5178Y methylthioinosine.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosine Nucleotides; Guanosine Tri | 1973 |
Letter: The cytotoxic effects of a new antibiotic vermicule.
Topics: Adenine; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Carbon Radioisotopes; Carcinom | 1974 |
Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea.
Topics: Adenine; Adenoma; Animals; Bone Marrow; Carbon Isotopes; DNA, Neoplasm; Guanine; Kidney; Liver; Lung | 1971 |
Nuclear uptake of exogenous DNA by mammalian cells in culture.
Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleus; Chromosomes; Culture Techniques; DNA; Guanine; Lymp | 1968 |
Origin of urinary methylated purines.
Topics: Adenine; Animals; Carbon Isotopes; Guanine; Humans; Lymphoma; Male; Mammary Neoplasms, Experimental; | 1966 |
Studies on the biochemical mode of action of a cytotoxic methylhydrazine derivative, N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide.
Topics: Adenine; Amines; Animals; Antineoplastic Agents; Carbon Isotopes; DNA; Formates; Guanine; Hydrazines | 1966 |