Page last updated: 2024-10-16

adenine and Lymphoma

adenine has been researched along with Lymphoma in 54 studies

Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.

Research Excerpts

ExcerptRelevanceReference
"2-Amino-N6-hydroxyadenine (AHA) was tested in the mouse lymphoma L5178Y tk +/- assay using the microtitre cloning technique over concentrations from 0."7.68The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk +/- 3.7.2C mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei. ( Bridges, BA; Cole, J; Richmond, FN, 1991)
"2-Amino-N6-hydroxyadenine (AHA) was tested in the mouse lymphoma L5178Y tk +/- assay using the microtitre cloning technique over concentrations from 0."3.68The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk +/- 3.7.2C mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei. ( Bridges, BA; Cole, J; Richmond, FN, 1991)
"Twenty-six patients with advanced cancer underwent acetylator phenotyping with caffeine and were assigned to a dose level."2.67Phase I study of amonafide dosing based on acetylator phenotype. ( Berezin, F; Janisch, L; Lane, LB; Mick, R; Ratain, MJ; Schilsky, RL; Vogelzang, NJ, 1993)
" Here side effects of ibrutinib have been summarized and important considerations in the management of these adverse events have been reviewed."2.61Management of adverse effects/toxicity of ibrutinib. ( Paydas, S, 2019)
" KIN-8194 demonstrated excellent bioavailability and pharmacokinetic parameters, with good tolerance in rodent models at pharmacologically achievable and active doses."1.62The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance. ( Anderson, KC; Buhrlage, SJ; Cameron, M; Castillo, JJ; Che, J; Chen, JG; Demos, MG; Gray, NS; Guerrera, ML; Hunter, ZR; Kofides, A; Liu, X; Meid, K; Munshi, M; Munshi, NC; Patterson, CJ; Tan, L; Treon, SP; Tsakmaklis, N; Wang, J; Xu, L; Yang, G, 2021)
"Increased aspergillosis was observed with ibrutinib monotherapy and DA-TEDDi-R."1.46Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma. ( Bhaumik, S; Butman, JA; Ceribelli, M; Chen, L; Cole, DE; Desai, JV; Dunleavy, K; Gea-Banacloche, J; Heiss, J; Higham, CS; Jaffe, ES; Lionakis, MS; Little, RF; Lucas, N; Melani, C; Pittaluga, S; Roschewski, M; Schmitz, R; Staudt, LM; Steinberg, SM; Stetler-Stevenson, M; Thomas, CJ; Widemann, BC; Wilson, WH; Yang, Y, 2017)
"We report a case of autoimmune thrombocytopenia associated with acute reverse seroconversion of hepatitis B in a patient who was initially hepatitis B virus surface antigen negative and hepatitis B virus surface antibody positive."1.34[Autoimmune thrombopenia associated with hepatitis B reactivation (reverse seroconversion) after autologous hematopoietic stem cell transplantation]. ( Aubourg, A; Bacq, Y; d'Alteroche, L; Gaudy, C; Senecal, D, 2007)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199017 (31.48)18.7374
1990's6 (11.11)18.2507
2000's4 (7.41)29.6817
2010's16 (29.63)24.3611
2020's11 (20.37)2.80

Authors

AuthorsStudies
Malfona, F1
Testi, AM1
Moleti, ML1
Petrucci, L1
Leccisotti, L1
Martelli, M1
Di Rocco, A1
Jimenez, JE1
Dai, D1
Xu, G1
Zhao, R1
Li, T1
Pan, T1
Wang, L1
Lin, Y1
Wang, Z1
Jaffray, D1
Hazle, JD1
Macapinlac, HA1
Wu, J1
Lu, Y1
Grainger, BT1
Issa, S2
Lauer, EM1
Waterhouse, M1
Braig, M1
Mutter, J1
Bleul, S1
Duque-Afonso, J1
Duyster, J1
Marks, R1
Reinacher, PC1
Prinz, M1
Illerhaus, G1
Finke, J1
Schorb, E1
Scherer, F1
Lewis, KL1
Chin, CK1
Manos, K1
Casey, J1
Hamad, N1
Crawford, J1
Ho, SJ1
Grigg, A1
Wood, P1
Gandhi, MK1
Do, B1
Nastoupil, L1
Hawkes, EA1
Cheah, CY1
Chen, F1
Pang, D1
Guo, H1
Ou, Q1
Wu, X1
Jiang, X1
Wei, X1
Liu, S1
Huang, L1
Liang, Z1
Zhou, D1
Li, W1
Meitlis, I1
Allenspach, EJ1
Bauman, BM1
Phan, IQ1
Dabbah, G1
Schmitt, EG1
Camp, ND1
Torgerson, TR1
Nickerson, DA1
Bamshad, MJ1
Hagin, D1
Luthers, CR1
Stinson, JR1
Gray, J1
Lundgren, I1
Church, JA1
Butte, MJ1
Jordan, MB1
Aceves, SS1
Schwartz, DM1
Milner, JD1
Schuval, S1
Skoda-Smith, S1
Cooper, MA1
Starita, LM1
Rawlings, DJ1
Snow, AL1
James, RG1
Claves, F1
Siest, R1
Lefebvre, C1
Valmary-Degano, S1
Carras, S1
Yang, G1
Wang, J1
Tan, L1
Munshi, M1
Liu, X1
Kofides, A1
Chen, JG1
Tsakmaklis, N1
Demos, MG1
Guerrera, ML1
Xu, L1
Hunter, ZR1
Che, J1
Patterson, CJ1
Meid, K1
Castillo, JJ1
Munshi, NC1
Anderson, KC1
Cameron, M1
Buhrlage, SJ1
Gray, NS1
Treon, SP1
Gángó, A1
Kiss, R1
Farkas, P1
Hanna, E1
Demeter, J1
Deák, B1
Lévai, D1
Kotmayer, L1
Alpár, D1
Matolcsy, A1
Bödör, C1
Mátrai, Z1
Timár, B1
Feldman, RC1
Hyman, DA1
Price, WN1
Ratain, MJ2
Lionakis, MS1
Dunleavy, K1
Roschewski, M1
Widemann, BC1
Butman, JA1
Schmitz, R1
Yang, Y1
Cole, DE1
Melani, C1
Higham, CS1
Desai, JV1
Ceribelli, M1
Chen, L1
Thomas, CJ1
Little, RF1
Gea-Banacloche, J1
Bhaumik, S1
Stetler-Stevenson, M1
Pittaluga, S1
Jaffe, ES1
Heiss, J1
Lucas, N1
Steinberg, SM1
Staudt, LM1
Wilson, WH1
Guha, A1
Derbala, MH1
Zhao, Q1
Wiczer, TE1
Woyach, JA1
Byrd, JC1
Awan, FT1
Addison, D1
Grommes, C1
Tang, SS1
Wolfe, J1
Kaley, TJ1
Daras, M1
Pentsova, EI1
Piotrowski, AF1
Stone, J1
Lin, A1
Nolan, CP1
Manne, M1
Codega, P1
Campos, C1
Viale, A1
Thomas, AA1
Berger, MF1
Hatzoglou, V1
Reiner, AS1
Panageas, KS1
DeAngelis, LM1
Mellinghoff, IK1
Tarantelli, C1
Gaudio, E1
Cascione, L1
Stathis, A1
Zucca, E1
Bertoni, F1
Paydas, S1
Soussain, C2
Choquet, S2
Blonski, M1
Leclercq, D1
Houillier, C2
Rezai, K1
Bijou, F1
Houot, R1
Boyle, E2
Gressin, R1
Nicolas-Virelizier, E1
Barrie, M1
Moluçon-Chabrot, C1
Lelez, ML1
Clavert, A1
Coisy, S1
Leruez, S1
Touitou, V1
Cassoux, N1
Daniau, M1
Ertault de la Bretonnière, M1
El Yamani, A1
Ghesquières, H1
Hoang-Xuan, K2
Vargas, L1
Hamasy, A1
Nore, BF1
Smith, CI1
Turetsky, A1
Kim, E1
Kohler, RH1
Miller, MA1
Weissleder, R1
Sagiv-Barfi, I1
Kohrt, HE1
Burckhardt, L1
Czerwinski, DK1
Levy, R1
Grisafi, D1
Maestro, A1
Grumi, C1
Piazzoni, L1
Tirone, G1
Fiore, W1
Tessari, R1
Gianardi, V1
Gatti, M1
Tasca, F1
Generali, D1
Ravelli, A1
Lanza, F1
Scaglione, F1
Iida, S1
Cheson, BD1
Leong, DP1
Caron, F1
Hillis, C1
Duan, A1
Healey, JS1
Fraser, G1
Siegal, D1
Cai, Q1
Chen, K1
Chen, J1
Wu, S1
Geng, Q1
Huang, H1
Lin, T1
Jiang, W1
Xia, Z1
Duan, H1
Rao, H1
Yao, M1
Hu, L1
Chamoun, K1
Larrieu-Ciron, D1
Al Jijakli, A1
Delrieu, V1
Delwail, V1
Morschhauser, F1
Feeney, SA1
McCaughey, C1
Watt, AP1
Agnaf, MR1
McDougall, N1
Wend, UC1
Gerlich, WH1
Coyle, PV1
SARTORELLI, AC4
UPCHURCH, HF1
BIEBER, AL1
CHANG, PK1
FISCHER, GA1
Goursaud, S1
Pineau, N1
Becq-Giraudon, L1
Gressens, P1
Muller, JM1
Janet, T1
Sharif, FA1
Yilmaz, Y1
Zieske, A1
Qumsiyeh, MB1
Aubourg, A1
d'Alteroche, L1
Senecal, D1
Gaudy, C1
Bacq, Y1
Zápotocký, M1
Hanzalová, J1
Starková, J1
Votruba, I1
Holý, A1
Otová, B1
Nguyen, BT1
El Sayed, YM1
Sadée, W2
Buchwald, M1
Ullman, B4
Martin, DW1
Makukho, LV1
Volkolupova, OP1
Mick, R1
Berezin, F1
Janisch, L1
Schilsky, RL1
Vogelzang, NJ1
Lane, LB1
Morgan, AJ1
Murray, KJ1
Challiss, RA1
Clive, D1
Glover, P1
Krehl, R1
Poorman-Allen, P1
Evans, HH1
Mencl, J1
Ricanati, M1
DiSalvo, C1
Varnes, ME1
Cole, J1
Richmond, FN1
Bridges, BA1
Hanson, S2
McCartan, K1
Sabina, RL1
Holmes, EW1
Beck, J1
Duan, DS1
Plagemann, PG1
Wohlhueter, RM1
Adamson, RH1
Ablashi, DV1
Cicmanec, JL1
Dalgard, DW1
Tyrsted, G1
Warnick, CT1
Kim, SC1
Paterson, AR1
Fuska, J1
Ivanitskaya, L1
Horáková, K1
Kuhr, I1
Frei, JV1
Robins, AB1
Taylor, DM1
Mandel, LR1
Srinivasan, PR1
Borek, E1
Tsunamura, S1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Efficacy and Safety of IBER Salvage Treatment Followed by Ibrutinib Maintenance for Transplant-ineligible Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL): a Multicenter, Single-arm, Prospective Phase II Study[NCT04066920]Phase 230 participants (Anticipated)Interventional2019-10-01Not yet recruiting
Implanted Loop Recorders (ILR) for the Detection and Management of Arrhythmia in Patients Treated With Bruton Tyrosine Kinase (BTK) Inhibitors[NCT05643235]50 participants (Anticipated)Interventional2022-11-01Recruiting
A Phase I/II Trial of the Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Patients With Newly Diagnosed or Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCN[NCT02315326]Phase 1/Phase 2109 participants (Anticipated)Interventional2014-12-31Recruiting
Phase II Study of Ibrutinib in Patients With Relapsed or Refractory Primary Central Nervous Lymphoma or Intraocular Lymphoma[NCT02542514]Phase 252 participants (Actual)Interventional2015-09-30Completed
Long-term Effect of Chronic Ibrutinib Therapy on Left Atrial Function[NCT03751410]40 participants (Actual)Observational [Patient Registry]2018-12-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for adenine and Lymphoma

ArticleYear
Bing-Neel syndrome presenting as isolated CNS lymphoplasmacytic lymphoma: A case report and review of the literature.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 71

    Topics: Adenine; Female; Humans; Lymphoma; Meningeal Carcinomatosis; Middle Aged; Piperidines; Pyrazoles; Py

2020
Management of adverse effects/toxicity of ibrutinib.
    Critical reviews in oncology/hematology, 2019, Volume: 136

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Atrial Fibrillation; Drug-Related Side Effects and Adv

2019
Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.
    Scandinavian journal of immunology, 2013, Volume: 78, Issue:2

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Agammaglobulinemia; Antineoplastic Agents; Autoimmunit

2013
Ibrutinib: from bench side to clinical implications.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:9

    Topics: Adenine; Antineoplastic Agents; Biomedical Research; Humans; Leukemia, Lymphocytic, Chronic, B-Cell;

2015
Overview: A New Era of Cancer Genomics in Lymphoid Malignancies.
    Oncology, 2015, Volume: 89 Suppl 1

    Topics: Adenine; Antineoplastic Agents; Biomarkers, Tumor; Clinical Trials as Topic; Genome, Human; Genomics

2015
Speed bumps on the road to a chemotherapy-free world for lymphoma patients.
    Blood, 2016, 07-21, Volume: 128, Issue:3

    Topics: Adenine; Clinical Trials as Topic; Drug Design; Humans; Lymphoma; Piperidines; Purines; Pyrazoles; P

2016
The risk of atrial fibrillation with ibrutinib use: a systematic review and meta-analysis.
    Blood, 2016, 07-07, Volume: 128, Issue:1

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Atrial Fibrillation; Humans; Incidence; Leuke

2016

Trials

4 trials available for adenine and Lymphoma

ArticleYear
Ibrutinib for central nervous system lymphoma: the Australasian Lymphoma Alliance/MD Anderson Cancer Center experience.
    British journal of haematology, 2021, Volume: 192, Issue:6

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Disease-Free Survival; Fe

2021
Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma.
    Blood, 2019, 01-31, Volume: 133, Issue:5

    Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Antineoplastic Agents; Antineoplastic Com

2019
Ibrutinib monotherapy for relapse or refractory primary CNS lymphoma and primary vitreoretinal lymphoma: Final analysis of the phase II 'proof-of-concept' iLOC study by the Lymphoma study association (LYSA) and the French oculo-cerebral lymphoma (LOC) net
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 117

    Topics: Adenine; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Drug Resistance, Neoplasm; Femal

2019
Phase I study of amonafide dosing based on acetylator phenotype.
    Cancer research, 1993, May-15, Volume: 53, Issue:10 Suppl

    Topics: Acetylation; Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female;

1993

Other Studies

43 other studies available for adenine and Lymphoma

ArticleYear
Efficacy of ibrutinib as salvage treatment in a secondary central nervous system lymphoma (SCNSL) progressed after chemorefractory Primary Mediastinal B Cell Lymphoma (PMBCL).
    Leukemia & lymphoma, 2022, Volume: 63, Issue:2

    Topics: Adenine; Central Nervous System; Central Nervous System Neoplasms; Humans; Lymphoma; Lymphoma, B-Cel

2022
Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma.
    Clinical nuclear medicine, 2022, Mar-01, Volume: 47, Issue:3

    Topics: Adenine; Fluorodeoxyglucose F18; Humans; Lymphoma; Piperidines; Positron Emission Tomography Compute

2022
Ibrutinib in patients with relapsed/refractory central nervous system lymphoma: A retrospective single-centre analysis.
    British journal of haematology, 2020, Volume: 190, Issue:2

    Topics: Adenine; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Female; Humans; Lymphoma; Male;

2020
Clinical outcomes of newly diagnosed primary CNS lymphoma treated with ibrutinib-based combination therapy: A real-world experience of off-label ibrutinib use.
    Cancer medicine, 2020, Volume: 9, Issue:22

    Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Antineoplastic Combined Chemotherapy Prot

2020
Multiplexed Functional Assessment of Genetic Variants in CARD11.
    American journal of human genetics, 2020, 12-03, Volume: 107, Issue:6

    Topics: Adenine; B-Cell CLL-Lymphoma 10 Protein; B-Lymphocytes; CARD Signaling Adaptor Proteins; Cell Line;

2020
Dramatic Efficacy of Ibrutinib in a Schnitzler Syndrome Case with Indolent Lymphoma.
    Journal of clinical immunology, 2021, Volume: 41, Issue:6

    Topics: Adenine; Female; Humans; Interleukin-1; Lymphoma; Middle Aged; Piperidines; Schnitzler Syndrome

2021
The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance.
    Blood, 2021, 11-18, Volume: 138, Issue:20

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug

2021
Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax.
    Pathology, 2022, Volume: 54, Issue:1

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Female; Genes,

2022
Negative innovation: when patents are bad for patients.
    Nature biotechnology, 2021, Volume: 39, Issue:8

    Topics: Adenine; Antineoplastic Agents; Humans; Leukemia; Lymphoma; Patents as Topic; Patient Harm; Piperidi

2021
Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.
    Cancer cell, 2017, 06-12, Volume: 31, Issue:6

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Animals; Aspergillosis; Brain

2017
Ventricular Arrhythmias Following Ibrutinib Initiation for Lymphoid Malignancies.
    Journal of the American College of Cardiology, 2018, 08-07, Volume: 72, Issue:6

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Cohort Studies; Female; Follow-Up Studies; Human

2018
In vitro demonstration of synergism with pixantrone combined with targeted agents in lymphomas.
    British journal of haematology, 2019, Volume: 186, Issue:1

    Topics: Adenine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Huma

2019
Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.
    Scientific reports, 2014, Apr-24, Volume: 4

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Binding Sites; Cell Line, Tumor; Gene Express

2014
Ibrutinib enhances the antitumor immune response induced by intratumoral injection of a TLR9 ligand in mouse lymphoma.
    Blood, 2015, Mar-26, Volume: 125, Issue:13

    Topics: Adenine; Adjuvants, Immunologic; Animals; Cell Line; Drug Synergism; Female; Injections, Intralesion

2015
The Effect of Prophylactic Lamivudine plus Adefovir Therapy Compared with Lamivudine Alone in Preventing Hepatitis B Reactivation in Lymphoma Patients with High Baseline HBV DNA during Chemotherapy.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; DNA, Viral; Drug Inter

2016
Ibrutinib monotherapy in relapsed/refractory CNS lymphoma: A retrospective case series.
    Neurology, 2017, 01-03, Volume: 88, Issue:1

    Topics: Adenine; Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Female; Follow-Up Studies; H

2017
Reactivation of occult hepatitis B virus infection following cytotoxic lymphoma therapy in an anti-HBc negative patient.
    Journal of medical virology, 2013, Volume: 85, Issue:4

    Topics: Adenine; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antiviral Agents; DNA,

2013
PHYSIOLOGICAL DISPOSITION AND THERAPEUTIC CONSEQUENCES OF ADENINE ADMINISTERED VIA THE GASTROINTESTINAL TRACT IN NORMAL AND TUMOR-BEARING MICE.
    Cancer research, 1963, Volume: 23

    Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatoc

1963
SOME INHIBITORY PROPERTIES OF 6-N-HYDROXYLAMINOPURINE: AN ANALOG OF ADENINE AND HYPOXANTHINE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Glycine; Guanine Nucleotide

1964
Human H9 cells proliferation is differently controlled by vasoactive intestinal peptide or peptide histidine methionine: implication of a GTP-insensitive form of VPAC1 receptor.
    Journal of neuroimmunology, 2005, Volume: 158, Issue:1-2

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Analysis of Variance; Blotting, Southern; Bromodeoxyuridine; C

2005
Natural killer cell lymphoma/leukemia with homozygous loss of p27/kip1.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:6

    Topics: Adenine; Aged; Amino Acid Sequence; Base Sequence; Cyclin-Dependent Kinase Inhibitor p27; Cytogeneti

2005
[Autoimmune thrombopenia associated with hepatitis B reactivation (reverse seroconversion) after autologous hematopoietic stem cell transplantation].
    Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:1

    Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Hematopoietic Stem Cell T

2007
Experimental therapy with 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): origin of resistance.
    Folia biologica, 2007, Volume: 53, Issue:3

    Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expressio

2007
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Adenine; Adenosine; Alanine; Animals; Antimetabolites, Antineoplastic; Cell Division; DNA Replicatio

1984
Biochemical and genetic analysis of AMP deaminase deficiency in cultured mammalian cells.
    The Journal of biological chemistry, 1981, Oct-25, Volume: 256, Issue:20

    Topics: Adenine; AMP Deaminase; Animals; Cell Division; Cell Line; Guanosine Triphosphate; Kinetics; Lymphom

1981
[Use of an express method in studying the cytotoxic action of antitumor antibiotics].
    Antibiotiki, 1981, Volume: 26, Issue:3

    Topics: Adenine; Animals; Antibiotics, Antineoplastic; Carbon Radioisotopes; Cells, Cultured; Drug Evaluatio

1981
Comparison of methods to assess cyclic AMP turnover under conditions of agonist stimulation in 1321N1 astrocytoma cells.
    Biochemical Society transactions, 1992, Volume: 20, Issue:2

    Topics: Adenine; Adenosine Triphosphate; Animals; Astrocytoma; Carbon Radioisotopes; Cell Line; Cyclic AMP;

1992
Mutagenicity of 2-amino-N6-hydroxyadenine (AHA) at three loci in L5178Y/tk+/- mouse lymphoma cells: molecular and preliminary cytogenetic characterizations of AHA-induced tk-/- mutants.
    Mutation research, 1991, Volume: 253, Issue:1

    Topics: Adenine; Animals; Blotting, Southern; Cell Survival; Chromosome Banding; Hypoxanthine Phosphoribosyl

1991
Mutagenicity of 2-amino-N6-hydroxyadenine at the tk locus in L5178Y strains differing in repair capabilities and karyotype.
    Mutation research, 1991, Volume: 253, Issue:1

    Topics: Adenine; Animals; Cell Survival; DNA Damage; DNA Repair; Free Radicals; Lymphoma; Mice; Mutagenicity

1991
The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk +/- 3.7.2C mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei.
    Mutation research, 1991, Volume: 253, Issue:1

    Topics: Adenine; Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Lymphoma; Mice;

1991
Adenylate deaminase deficiency in a mutant murine T cell lymphoma cell line.
    The Journal of biological chemistry, 1990, Jul-15, Volume: 265, Issue:20

    Topics: Adenine; AMP Deaminase; Animals; Blotting, Southern; Cell Division; Cell Line; Cell Survival; DNA, N

1990
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug;

1989
AMP deaminase and thymidine kinase deficiencies in a mutant mouse S49 cell clone.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine; AMP Deaminase; Animals; Cell Division; Clone Cells; Dose-Response Relationship, Drug; Hybri

1989
Distinct effects of adenine and guanine starvation on DNA synthesis associated with different pool sizes of nucleotide precursors.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Adenine; Animals; Cell Compartmentation; Cell Cycle; Cell Line; Deoxyadenosines; DNA Replication; DN

1987
S49 mouse lymphoma cells are deficient in hypoxanthine transport.
    Biochimica et biophysica acta, 1986, Feb-13, Volume: 855, Issue:1

    Topics: Adenine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Hypoxanthin

1986
Chemotherapy of Herpesvirus saimiri induced lymphoma-leukemia in the owl monkey.
    Journal of medical primatology, 1974, Volume: 3, Issue:1

    Topics: Adenine; Animals; Arabinose; Cyclophosphamide; Cytarabine; Disease Models, Animal; Haplorhini; Herpe

1974
Inhibition of the synthesis of 5-phosphoribosyl-1-pyrophosphate by 3'-deoxy-adenosine and structurally related nucleoside analogs.
    Biochimica et biophysica acta, 1968, Feb-26, Volume: 155, Issue:2

    Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Diphosphates; Glucose; Glucosyltransfer

1968
Inhibition of purine synthesis de novo in cultured L5178Y methylthioinosine.
    Biochemical pharmacology, 1973, Nov-01, Volume: 22, Issue:21

    Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosine Nucleotides; Guanosine Tri

1973
Letter: The cytotoxic effects of a new antibiotic vermicule.
    The Journal of antibiotics, 1974, Volume: 27, Issue:2

    Topics: Adenine; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Carbon Radioisotopes; Carcinom

1974
Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea.
    International journal of cancer, 1971, May-15, Volume: 7, Issue:3

    Topics: Adenine; Adenoma; Animals; Bone Marrow; Carbon Isotopes; DNA, Neoplasm; Guanine; Kidney; Liver; Lung

1971
Nuclear uptake of exogenous DNA by mammalian cells in culture.
    Nature, 1968, Mar-30, Volume: 217, Issue:5135

    Topics: Adenine; Animals; Carbon Isotopes; Cell Nucleus; Chromosomes; Culture Techniques; DNA; Guanine; Lymp

1968
Origin of urinary methylated purines.
    Nature, 1966, Feb-05, Volume: 209, Issue:5023

    Topics: Adenine; Animals; Carbon Isotopes; Guanine; Humans; Lymphoma; Male; Mammary Neoplasms, Experimental;

1966
Studies on the biochemical mode of action of a cytotoxic methylhydrazine derivative, N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Adenine; Amines; Animals; Antineoplastic Agents; Carbon Isotopes; DNA; Formates; Guanine; Hydrazines

1966