adenine has been researched along with Liver Failure, Acute in 9 studies
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spontaneous reactivation of chronic hepatitis B (CHB) is an important cause of acute-on-chronic liver failure (ACLF)." | 2.76 | Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure. ( Garg, H; Garg, V; Kumar, A; Kumar, M; Sarin, SK; Sharma, BC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahn, A | 1 |
| Horsley-Silva, JL | 1 |
| Lam-Himlin, DM | 1 |
| Reeder, CB | 1 |
| Douglas, DD | 1 |
| Carey, EJ | 1 |
| Sutherland, N | 1 |
| Li Wai Suen, CFD | 1 |
| Mills, C | 1 |
| Lokan, J | 1 |
| Sinclair, M | 1 |
| Jain, P | 1 |
| Garg, H | 1 |
| Sarin, SK | 1 |
| Kumar, M | 1 |
| Garg, V | 1 |
| Sharma, BC | 1 |
| Kumar, A | 1 |
| Liu, T | 1 |
| Zhang, C | 1 |
| Wang, Y | 1 |
| Dai, CY | 1 |
| Yeh, ML | 1 |
| Huang, CF | 1 |
| Huang, JF | 1 |
| Yu, ML | 1 |
| Chuang, WL | 1 |
| Tillmann, HL | 1 |
| Zachou, K | 1 |
| Dalekos, GN | 1 |
| Wang, J | 1 |
| Wang, M | 1 |
| Huang, Y | 1 |
| Thabut, D | 1 |
| Ratziu, V | 1 |
| Bernard-Chabert, B | 1 |
| Poynard, T | 1 |
| Benhamou, Y | 1 |
| Thibault, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tenofovir Reduces Morbidity and Mortality in Patients With Spontaneous Reactivation of Hepatitis B Presenting as Acute-on-chronic Liver Failure (ACLF): A Randomized Placebo Controlled Trial[NCT01074645] | Phase 4 | 27 participants (Actual) | Interventional | 2007-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for adenine and Liver Failure, Acute
| Article | Year |
|---|---|
Lenalidomide-induced acute liver failure.
Topics: Adenine; Aged, 80 and over; Antineoplastic Agents; Antiviral Agents; Hepatitis B, Chronic; Humans; L | 2009 |
Management of severe acute to fulminant hepatitis B: to treat or not to treat or when to treat?
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Interferons; Lamivudine; Liver Failure, Acu | 2012 |
1 trial available for adenine and Liver Failure, Acute
| Article | Year |
|---|---|
Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Ch | 2011 |
6 other studies available for adenine and Liver Failure, Acute
| Article | Year |
|---|---|
Ibrutinib-induced acute liver failure.
Topics: Adenine; Biomarkers; Combined Modality Therapy; Female; Humans; Liver Failure, Acute; Middle Aged; P | 2018 |
Fibrosing Cholestatic Hepatitis-Like Syndrome in an Immunocompetent Patient With an Acute Flare of Chronic Hepatitis B.
Topics: Adenine; Biopsy, Needle; Cholestasis; Disease Progression; Follow-Up Studies; Hepatitis B, Chronic; | 2019 |
Proper antiviral therapy for hepatitis B virus-associated acute-on-chronic liver failure.
Topics: Adenine; Antiviral Agents; End Stage Liver Disease; Guanine; Hepatitis B, Chronic; Humans; Liver Fai | 2011 |
Outcome of patients suffering from a spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure and treated with antivirals.
Topics: Adenine; Antiviral Agents; DNA, Viral; Female; Hepatitis B, Chronic; Humans; Liver Failure, Acute; M | 2011 |
Acute liver failure resulting from discontinuation of nucleoside analogues in chronic hepatitis B patients: a report of two cases.
Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Histocytochemistry; Humans; Lamivud | 2013 |
Unsuccessful rescue therapy with adefovir dipivoxil for lamivudine resistant HBV in a patient with liver failure.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Fatal Outcome; Female; Hepatitis B, Chronic; Huma | 2003 |