adenine has been researched along with Lactic Acidosis in 16 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present an uncommon case of lactic acidosis after concomitant administration of Metformin and Tenofovir." | 7.77 | Lactic acidosis after concomitant treatment with metformin and tenofovir in a patient with HIV infection. ( Alivanis, P; Aperis, G; Arvanitis, A; Paliouras, C; Zervos, A, 2011) |
| "We describe a 49-year-old man with human immunodeficiency virus infection and stable chronic renal insufficiency who developed acute oliguric renal failure and severe lactic acidosis and who died several weeks after tenofovir was added to an antiretroviral regimen that included didanosine." | 7.72 | Fatal lactic acidosis and acute renal failure after addition of tenofovir to an antiretroviral regimen containing didanosine. ( Chou, S; Murphy, MD; O'Hearn, M, 2003) |
| "Lactic acidosis is an uncommon but potentially life-threatening adverse effect of didanosine." | 7.72 | Fatal lactic acidosis associated with coadministration of didanosine and tenofovir disoproxil fumarate. ( Fung, HB; Guo, Y, 2004) |
| "Lactic acidosis is a rare but serious side effect in individuals receiving nucleoside reverse transcriptase inhibitors." | 5.91 | Severe lactic acidosis during tenofovir disoproxil fumarate and cobicistat combination for HIV patient. ( Isoda, A; Matsumoto, M; Mihara, M; Sawamura, M, 2023) |
| "Fatal lactic acidosis has been reported while on the treatment with Nucleoside/nucleotide analogues (NA) for the treatment of hepatitis B, C and HIV." | 5.48 | Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient. ( Alsunaid, SR; Ashraf, H; Soubani, AO, 2018) |
| "None of the patients developed lactic acidosis during follow-up [median: 58 (6-155) months]." | 3.85 | Lactate serum concentrations during treatment with nucleos(t)ide analogues in hepatitis B with or without cirrhosis. ( Aggeletopoulou, I; Anastassiou, ED; Assimakopoulos, S; Gogos, C; Kalafateli, M; Labropoulou-Karatza, C; Mandellou, M; Taprantzi, D; Thomopoulos, K; Triantos, C; Tselekouni, P; Tsiaoussis, G; Vourli, G, 2017) |
| "We present an uncommon case of lactic acidosis after concomitant administration of Metformin and Tenofovir." | 3.77 | Lactic acidosis after concomitant treatment with metformin and tenofovir in a patient with HIV infection. ( Alivanis, P; Aperis, G; Arvanitis, A; Paliouras, C; Zervos, A, 2011) |
| "We describe a 49-year-old man with human immunodeficiency virus infection and stable chronic renal insufficiency who developed acute oliguric renal failure and severe lactic acidosis and who died several weeks after tenofovir was added to an antiretroviral regimen that included didanosine." | 3.72 | Fatal lactic acidosis and acute renal failure after addition of tenofovir to an antiretroviral regimen containing didanosine. ( Chou, S; Murphy, MD; O'Hearn, M, 2003) |
| "Lactic acidosis is an uncommon but potentially life-threatening adverse effect of didanosine." | 3.72 | Fatal lactic acidosis associated with coadministration of didanosine and tenofovir disoproxil fumarate. ( Fung, HB; Guo, Y, 2004) |
| "Increased risk of lactic acidosis has also been described for those with impaired liver and renal function taking entecavir." | 2.50 | Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment. ( Fung, J; Lai, CL; Seto, WK; Yuen, MF, 2014) |
| "Lactic acidosis is a rare but serious side effect in individuals receiving nucleoside reverse transcriptase inhibitors." | 1.91 | Severe lactic acidosis during tenofovir disoproxil fumarate and cobicistat combination for HIV patient. ( Isoda, A; Matsumoto, M; Mihara, M; Sawamura, M, 2023) |
| "Fatal lactic acidosis has been reported while on the treatment with Nucleoside/nucleotide analogues (NA) for the treatment of hepatitis B, C and HIV." | 1.48 | Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient. ( Alsunaid, SR; Ashraf, H; Soubani, AO, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Arnouk, S | 1 |
| Whitsett, M | 1 |
| Papadopoulos, J | 1 |
| Stewart Lewis, Z | 1 |
| Dagher, NN | 1 |
| Feldman, DM | 1 |
| Park, JS | 1 |
| Isoda, A | 1 |
| Mihara, M | 1 |
| Matsumoto, M | 1 |
| Sawamura, M | 1 |
| Oyaizu-Toramaru, T | 1 |
| Suhara, T | 1 |
| Hayakawa, N | 1 |
| Nakamura, T | 1 |
| Kubo, A | 1 |
| Minamishima, S | 1 |
| Yamaguchi, K | 1 |
| Hishiki, T | 1 |
| Morisaki, H | 1 |
| Suematsu, M | 1 |
| Minamishima, YA | 1 |
| Triantos, C | 1 |
| Kalafateli, M | 1 |
| Aggeletopoulou, I | 1 |
| Mandellou, M | 1 |
| Assimakopoulos, S | 1 |
| Tselekouni, P | 1 |
| Taprantzi, D | 1 |
| Tsiaoussis, G | 1 |
| Vourli, G | 1 |
| Anastassiou, ED | 1 |
| Gogos, C | 1 |
| Labropoulou-Karatza, C | 1 |
| Thomopoulos, K | 1 |
| Alsunaid, SR | 1 |
| Ashraf, H | 1 |
| Soubani, AO | 1 |
| Fung, J | 1 |
| Seto, WK | 1 |
| Lai, CL | 1 |
| Yuen, MF | 1 |
| Aperis, G | 1 |
| Paliouras, C | 1 |
| Zervos, A | 1 |
| Arvanitis, A | 1 |
| Alivanis, P | 1 |
| Kazazis, C | 1 |
| Murphy, MD | 1 |
| O'Hearn, M | 1 |
| Chou, S | 1 |
| Campos, Y | 1 |
| García, A | 1 |
| del Hoyo, P | 1 |
| Jara, P | 1 |
| Martín, MA | 1 |
| Rubio, JC | 1 |
| Berbel, A | 1 |
| Barberá, JR | 1 |
| Ribacoba, R | 1 |
| Astudillo, A | 1 |
| Cabello, A | 1 |
| Ricoy, JR | 1 |
| Arenas, J | 1 |
| Rosso, R | 1 |
| Di Biagio, A | 1 |
| Ferrazin, A | 1 |
| Bassetti, M | 1 |
| Ciravegna, BW | 1 |
| Bassetti, D | 1 |
| Rivas, P | 1 |
| Polo, J | 1 |
| de Górgolas, M | 1 |
| Fernández-Guerrero, ML | 1 |
| Hansen, AB | 1 |
| Mathiesen, S | 1 |
| Gerstoft, J | 1 |
| Guo, Y | 1 |
| Fung, HB | 1 |
| Giola, M | 1 |
| Basilico, C | 1 |
| Grossi, P | 1 |
| Masiá, M | 1 |
| Gutiérrez, F | 1 |
| Padilla, S | 1 |
| Ramos, JM | 1 |
| Pascual, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized Open-Label Phase II Study of the Safety and Tolerability of Metformin in Combination With Standard Antimicrobial Treatment of Pulmonary Tuberculosis in People With TB and Co-infected With HIV[NCT04930744] | Phase 2 | 112 participants (Anticipated) | Interventional | 2021-08-03 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for adenine and Lactic Acidosis
| Article | Year |
|---|---|
Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment.
Topics: Acidosis, Lactic; Adenine; Administration, Oral; Antiviral Agents; Arabinofuranosyluracil; Dose-Resp | 2014 |
Severe metabolic acidosis and renal failure in an HIV-1 patient receiving tenofovir.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adenine; HIV Infections; Humans; Kidney Function Tests; Male; | 2004 |
Severe toxicity associated with the combination of tenofovir and didanosine: case report and review.
Topics: Acidosis, Lactic; Acute Disease; Adenine; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Fe | 2005 |
13 other studies available for adenine and Lactic Acidosis
| Article | Year |
|---|---|
Successful Treatment of Tenofovir Alafenamide-Induced Lactic Acidosis: A Case Report.
Topics: Acidosis, Lactic; Adenine; Antiviral Agents; Hepatitis B; Humans; Male; Middle Aged; Tenofovir | 2023 |
Severe lactic acidosis during tenofovir disoproxil fumarate and cobicistat combination for HIV patient.
Topics: Acidosis, Lactic; Adenine; Anti-HIV Agents; Cobicistat; Drug Combinations; Female; HIV Infections; H | 2023 |
Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment.
Topics: Acidosis, Lactic; Adenine; Animals; Disease Models, Animal; Enzyme Inhibitors; Gluconeogenesis; Kidn | 2017 |
Lactate serum concentrations during treatment with nucleos(t)ide analogues in hepatitis B with or without cirrhosis.
Topics: Acidosis, Lactic; Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Biomarkers; Drug Therap | 2017 |
Tenofovir alafenamide associated fatal lactic acidosis in an autologous hematopoietic stem cell transplant recipient.
Topics: Acidosis, Lactic; Adenine; Aged; Alanine; Antiviral Agents; Fatal Outcome; Hematopoietic Stem Cell T | 2018 |
Lactic acidosis after concomitant treatment with metformin and tenofovir in a patient with HIV infection.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adenine; Aged; Anti-HIV Agents; Diabetes Mellitus, Type 2; Dr | 2011 |
A case of lactic acidosis (LA) after administration of tenofovir and metformin in a diabetic patient with recently diagnosed HIV infection.
Topics: Acidosis, Lactic; Adenine; Anti-HIV Agents; Diabetes Mellitus, Type 2; HIV Infections; Humans; Hypog | 2011 |
Fatal lactic acidosis and acute renal failure after addition of tenofovir to an antiretroviral regimen containing didanosine.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Acti | 2003 |
Two pathogenic mutations in the mitochondrial DNA tRNA Leu(UUR) gene (T3258C and A3280G) resulting in variable clinical phenotypes.
Topics: Acidosis, Lactic; Adenine; Adult; Biopsy; Cardiomyopathies; Cytosine; DNA, Mitochondrial; Female; Gu | 2003 |
Fatal lactic acidosis and mimicking Guillain-Barré syndrome in an adolescent with human immunodeficiency virus infection.
Topics: Acidosis, Lactic; Adenine; Adolescent; Antiretroviral Therapy, Highly Active; Carbamates; Diagnosis, | 2003 |
Drug points: Fatal lactic acidosis associated with tenofovir.
Topics: Acidosis, Lactic; Adenine; Anti-HIV Agents; Fatal Outcome; Female; Humans; Middle Aged; Organophosph | 2003 |
Fatal lactic acidosis associated with coadministration of didanosine and tenofovir disoproxil fumarate.
Topics: Acidosis, Lactic; Adenine; Anti-HIV Agents; Area Under Curve; Comorbidity; Didanosine; Drug Interact | 2004 |
Fatal lactic acidosis associated with tenofovir and abacavir.
Topics: Acidosis, Lactic; Adenine; Anti-HIV Agents; Dideoxynucleosides; Fatal Outcome; HIV Infections; Human | 2005 |