adenine has been researched along with Kidney Failure, Chronic in 147 studies
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated whether quercetin could alleviate vascular calcification in experimental chronic renal failure rats induced by adenine." | 7.85 | Quercetin Attenuates Vascular Calcification through Suppressed Oxidative Stress in Adenine-Induced Chronic Renal Failure Rats. ( Chang, XY; Cui, L; Hao, LR; Wang, XZ; Zhang, L; Zhou, XR; Zhu, D, 2017) |
| "While body weight was decreased, kidney weight increased in DEP+adenine versus saline+adenine or DEP." | 7.83 | Prolonged Pulmonary Exposure to Diesel Exhaust Particles Exacerbates Renal Oxidative Stress, Inflammation and DNA Damage in Mice with Adenine-Induced Chronic Renal Failure. ( Ali, BH; Beegam, S; Hamadi, NK; Karaca, T; Nemmar, A; Yasin, J; Yuvaraju, P, 2016) |
| "In order to evaluate the efficacy, and explore the mechanism of SDG to inhibit the progression of renal fibrosis, study was carried out using the adenine-induced Wister rats as the CRF model, and losartan as postive control drug." | 7.80 | Chinese herbal medicine Shenqi Detoxification Granule inhibits fibrosis in adenine induced chronic renal failure rats. ( Cai, P; Ma, H; Meng, H; Peng, M; Si, G; Xu, Y; Zhang, X, 2014) |
| "Metanephros transplantation significantly reduced vascular calcium and phosphorus content and suppressed the progression of vascular calcification as indicated by von Kossa staining of the media of the thoracic aorta." | 7.78 | Metanephros transplantation inhibits the progression of vascular calcification in rats with adenine-induced renal failure. ( Hosoya, T; Kawamura, T; Matsumoto, K; Ohkido, I; Utsunomiya, Y; Yokoo, T; Yokote, S, 2012) |
| "Lamivudine is a safe, effective treatment for hepatitis B virus (HBV) reactivation after renal transplantation." | 7.73 | Treatment with adefovir dipivoxil in a renal transplant patient with renal insufficiency and lamivudine-resistant hepatitis B infection. ( Ceballos, M; Diaz, F; Garcia, A; Garcia, T; González, P; Mazuecos, A; Rivero, M, 2005) |
| " These results have demonstrated that oral dosing with adenine at 50 mg/kg for 28 days is suitable to induce a stable anemia associated with CKD in mice." | 5.48 | A novel approach to adenine-induced chronic kidney disease associated anemia in rodents. ( Hitomi, H; Kitada, K; Nakano, D; Nishiyama, A; Rahman, A; Sufiun, A; Yamazaki, D, 2018) |
| "But, treatment with diosgenin at a dose of 10, 20, and 40 mg/kg given via oral gavages causes reversion of all the above events in a dose-dependent manner." | 5.39 | Diosgenin attenuates vascular calcification in chronic renal failure rats. ( Arunagiri, P; Balamurugan, E; Barathkumar, TR; Manivannan, J; Raja, B; Sivasubramanian, J, 2013) |
| "We performed a cohort study of 290 chronic hepatitis B patients: 145 patients treated with 10 mg ADV and 145 patients unexposed to ADV at two community clinics, who were matched for age (+/-10 years), sex, and baseline eGFR." | 5.35 | Renal dysfunction in chronic hepatitis B patients treated with adefovir dipivoxil. ( Garcia, RT; Ha, NB; Levitt, BS; Nguyen, HA; Nguyen, KK; Nguyen, MH; Trinh, HN; Vu, AA, 2009) |
| "SKI protected against adenine-induced kidney injury and fibrosis and exerted anti-inflammatory, and antioxidant effects in CRF rats." | 4.12 | Protective effect and mechanism of Shenkang injection on adenine-induced chronic renal failure in rats. ( Chen, R; Sun, G; Sun, X; Xu, L; Zeng, W; Zhang, X, 2022) |
| " Here, we established a rat model with secondary hyperparathyroidism (SHPT) and bone disease induced by adenine and a high phosphorous diet and analyzed the skeletal characteristics." | 3.88 | A rat model of SHPT with bone abnormalities in CKD induced by adenine and a high phosphorus diet. ( Chen, Q; Liu, BC; Lv, LL; Ni, HF; Ni, LH; Song, KY; Tang, RN; Wang, B; Wang, FM; Wang, LT; Wu, M, 2018) |
| "This study investigated whether quercetin could alleviate vascular calcification in experimental chronic renal failure rats induced by adenine." | 3.85 | Quercetin Attenuates Vascular Calcification through Suppressed Oxidative Stress in Adenine-Induced Chronic Renal Failure Rats. ( Chang, XY; Cui, L; Hao, LR; Wang, XZ; Zhang, L; Zhou, XR; Zhu, D, 2017) |
| "While body weight was decreased, kidney weight increased in DEP+adenine versus saline+adenine or DEP." | 3.83 | Prolonged Pulmonary Exposure to Diesel Exhaust Particles Exacerbates Renal Oxidative Stress, Inflammation and DNA Damage in Mice with Adenine-Induced Chronic Renal Failure. ( Ali, BH; Beegam, S; Hamadi, NK; Karaca, T; Nemmar, A; Yasin, J; Yuvaraju, P, 2016) |
| "In order to evaluate the efficacy, and explore the mechanism of SDG to inhibit the progression of renal fibrosis, study was carried out using the adenine-induced Wister rats as the CRF model, and losartan as postive control drug." | 3.80 | Chinese herbal medicine Shenqi Detoxification Granule inhibits fibrosis in adenine induced chronic renal failure rats. ( Cai, P; Ma, H; Meng, H; Peng, M; Si, G; Xu, Y; Zhang, X, 2014) |
| "Cox proportional hazards and marginal structural models evaluated associations between tenofovir and time to first occurrence of proteinuria (two consecutive urine dipstick measurements ≥30 mg/dl), rapid decline in kidney function (≥3 ml/min per 1." | 3.78 | Association of tenofovir exposure with kidney disease risk in HIV infection. ( Choi, AI; Deeks, SG; Estrella, M; Grunfeld, C; Li, Y; Scherzer, R; Shlipak, MG, 2012) |
| "Metanephros transplantation significantly reduced vascular calcium and phosphorus content and suppressed the progression of vascular calcification as indicated by von Kossa staining of the media of the thoracic aorta." | 3.78 | Metanephros transplantation inhibits the progression of vascular calcification in rats with adenine-induced renal failure. ( Hosoya, T; Kawamura, T; Matsumoto, K; Ohkido, I; Utsunomiya, Y; Yokoo, T; Yokote, S, 2012) |
| " Uremia-related medial calcification was induced by feeding rats an adenine low-protein diet for 4 weeks." | 3.76 | Chondrocyte rather than osteoblast conversion of vascular cells underlies medial calcification in uremic rats. ( D'Haese, PC; Dauwe, S; De Broe, ME; De Schutter, T; Neven, E; Persy, V, 2010) |
| "Lamivudine is a safe, effective treatment for hepatitis B virus (HBV) reactivation after renal transplantation." | 3.73 | Treatment with adefovir dipivoxil in a renal transplant patient with renal insufficiency and lamivudine-resistant hepatitis B infection. ( Ceballos, M; Diaz, F; Garcia, A; Garcia, T; González, P; Mazuecos, A; Rivero, M, 2005) |
| "Acute renal failure is common in HIV-infected patients and is associated with acute infection and medication-related nephrotoxicity." | 2.44 | HIV-1 infection and the kidney: an evolving challenge in HIV medicine. ( de Silva, TI; Dockrell, DH; Griffin, MD; Post, FA, 2007) |
| "Secondary hyperparathyroidism is a complication of chronic renal failure that is associated with cardiovascular disease." | 1.62 | Parathyroid Hormone Induces Transition of Myofibroblasts in Arteriovenous Fistula and Increases Maturation Failure. ( Chen, CH; Chen, CY; Hsieh, HL; Hsu, SC; Huang, PH; Lin, FY; Liu, CT; Shih, CM; Shiu, YT; Sue, YM, 2021) |
| "To address the issues, a mice model of Chronic renal failure (CRF) was established by gavage 0." | 1.56 | Ameliorate effects of soybean soluble polysaccharide on adenine-induced chronic renal failure in mice. ( Hou, G; Huang, Q; Jin, M; Ye, M; Ye, Z; Zhang, X, 2020) |
| "Fractures averted, cases of ESRD averted, quality-adjusted life-years (QALYs) saved, costs, incremental cost-effectiveness ratios (ICERs), and maximum justifiable price for F/TAF compared with generic F/TDF." | 1.56 | Comparative Pricing of Branded Tenofovir Alafenamide-Emtricitabine Relative to Generic Tenofovir Disoproxil Fumarate-Emtricitabine for HIV Preexposure Prophylaxis: A Cost-Effectiveness Analysis. ( Freedberg, KA; Horn, T; McCann, NC; Paltiel, AD; Walensky, RP, 2020) |
| "Vascular calcification is highly prevalent in end-stage renal diseases and is predictive of cardiovascular events and mortality." | 1.51 | Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2. ( An, J; Huang, K; Li, Y; Liang, M; Tong, Q; Wang, C; Xu, W; Zhang, F, 2019) |
| "Kidney fibrosis was associated with upregulation of 6-keto-PGI2/TXB2 in the rat kidney tissue." | 1.51 | Comparison of the Effects of Indobufen and Warfarin in a Rat Model of Adenine-Induced Chronic Kidney Disease. ( Gong, J; He, Q; Jin, J; Li, Y; Lou, X; Zhao, L, 2019) |
| " When CCP dosage reached 200mg/kg/day, the area of renal pathological damage was decreased by 59." | 1.48 | Renoprotective effect of Chinese chive polysaccharides in adenine-induced chronic renal failure. ( Chena, HR; Li, QM; Lu, CQ; Luo, JP; Pan, LH; Zha, XQ, 2018) |
| " These results have demonstrated that oral dosing with adenine at 50 mg/kg for 28 days is suitable to induce a stable anemia associated with CKD in mice." | 1.48 | A novel approach to adenine-induced chronic kidney disease associated anemia in rodents. ( Hitomi, H; Kitada, K; Nakano, D; Nishiyama, A; Rahman, A; Sufiun, A; Yamazaki, D, 2018) |
| "Rats with adenine-induced chronic renal failure (ACRF) develop severe renal insufficiency and metabolic abnormalities that closely resemble those in patients with uremia." | 1.48 | Adenine-Induced Chronic Renal Failure in Rats: A Model of Chronic Renocardiac Syndrome with Left Ventricular Diastolic Dysfunction but Preserved Ejection Fraction. ( Guron, CW; Guron, G; Kashioulis, P; Lundgren, J; Nguy, L; Saeed, A; Shubbar, E, 2018) |
| "ω-3 PUFAs alleviated adenine-induced chronic renal failure through enhancing antioxidant stress and inhibiting inflammatory response via regulating Nrf2 and TGF-β/SMAD pathway." | 1.48 | Omega-3 polyunsaturated fatty acids alleviate adenine-induced chronic renal failure via regulating ROS production and TGF-β/SMAD pathway. ( Feng, ZP; Fu, P; Peng, HY; Xu, J, 2018) |
| "Rats with adenine-induced chronic renal failure (CRF) were prepared by feeding them an adenine-containing diet for four weeks." | 1.46 | PA21, a novel phosphate binder, improves renal osteodystrophy in rats with chronic renal failure. ( Kobayashi, M; Takeda, H; Tatemichi, S; Yaguchi, A, 2017) |
| "In this study, we established a chronic renal failure (CRF) model in rats induced by adenine administration prior to Mg implantation, aiming to predict if CRF patients are suitable for the use of Mg implants." | 1.43 | Biodegradable Magnesium (Mg) Implantation Does Not Impose Related Metabolic Disorders in Rats with Chronic Renal Failure. ( Li, Y; Liu, W; Qin, L; Wang, J; Xu, J, 2016) |
| "Rats with adenine-induced chronic renal failure (A-CRF) develop a reduced rate of relaxation of the thoracic aorta." | 1.43 | Adenine-induced chronic renal failure in rats decreases aortic relaxation rate and alters expression of proteins involved in vascular smooth muscle calcium handling. ( Guron, G; Jernås, M; Lundgren, J; Nguy, L; Nilsson, H; Nookaew, I; Olsson, B; Shubbar, E, 2016) |
| "Subjects with chronic renal failure (CRF) exhibit oxidative genome damage, which may predispose to carcinogenesis, and Gum acacia (GumA) ameliorates this condition in humans and animals." | 1.42 | Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats. ( Al Balushi, K; Al-Husseini, I; Ali, BH; Mandel, P; Nemmar, A; Ribeiro, DA; Schupp, N, 2015) |
| "Pathogenesis of adenine-induced chronic renal failure may involve inflammatory, immunological and/or oxidant mechanisms." | 1.42 | High-mobility group box-1 protein in adenine-induced chronic renal failure and the influence of gum arabic thereon. ( Al Shukaili, A; Al Za'abi, M; Ali, BH; Nemmar, A, 2015) |
| "Adenine treatment impaired kidney function: it lowered creatinine clearance and increased plasma concentrations of creatinine, urea, neutrophil gelatinase-associated lipocalin and vanin-1." | 1.40 | The effect of activated charcoal on adenine-induced chronic renal failure in rats. ( Al-Lawati, I; Ali, BH; Alza'abi, M; Beegam, S; Brand, S; Nemmar, A; Ramkumar, A; Schupp, N; Waly, MI, 2014) |
| "Vascular calcification is highly correlated with increased cardiovascular morbidity and mortality." | 1.40 | Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro. ( Feng, H; Lei, H; Li, H; Li, L; Wang, C; Wang, JY; Wu, D; Wu, LL; Zhou, Y, 2014) |
| "The adenine group was subdivided into a model control group (n = 7), a positive control group (200 mg/kg Jinshuibao capsule (JSB; n = 8), and two IF groups (200 mg/kg, n = 8; 100 mg/kg, n = 8)." | 1.39 | Nephroprotective effects of Isaria felina in rats with adenine-induced chronic renal failure. ( Bai, X; Ren, L; Yang, X; Zhang, H; Zhang, S, 2013) |
| "Rats with adenine-induced chronic renal failure (A-CRF) develop metabolic and cardiovascular abnormalities resembling those in patients with chronic kidney disease." | 1.39 | Rats with adenine-induced chronic renal failure develop low-renin, salt-sensitive hypertension and increased aortic stiffness. ( Carlström, M; Grimberg, E; Guron, G; Johansson, ME; Lundberg, JO; Lundgren, J; Nguy, L; Nilsson, H; Teerlink, T, 2013) |
| "After 1 week, rats with chronic renal failure were treated with vehicle, 375 or 750 mg/kg CaMg, or 750 mg/kg sevelamer by daily gavage for 5 weeks." | 1.39 | Effect of a magnesium-based phosphate binder on medial calcification in a rat model of uremia. ( Behets, GJ; D'Haese, PC; De Schutter, TM; Geryl, H; Gundlach, K; Neven, E; Passlick-Deetjen, J; Peter, ME; Steppan, S, 2013) |
| "But, treatment with diosgenin at a dose of 10, 20, and 40 mg/kg given via oral gavages causes reversion of all the above events in a dose-dependent manner." | 1.39 | Diosgenin attenuates vascular calcification in chronic renal failure rats. ( Arunagiri, P; Balamurugan, E; Barathkumar, TR; Manivannan, J; Raja, B; Sivasubramanian, J, 2013) |
| "Acetaminophen has no effect on the progression of renal damage in adenine-induced renal failure model rats." | 1.38 | Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats. ( Arimizu, K; Chuang, VT; Hirata, S; Irie, T; Ishitsuka, Y; Kadowaki, D; Kitamura, K; Maruyama, T; Narita, Y; Otagiri, M; Sumikawa, S; Taguchi, K, 2012) |
| "All three patients progressed to ESRD, within 1 month following renal biopsy in two and after 9 months in one." | 1.36 | Crystalline nephropathy due to 2,8-dihydroxyadeninuria: an under-recognized cause of irreversible renal failure. ( Boelkins, M; Broviac, J; Cornell, LD; Fidler, ME; Milliner, DS; Nasr, SH; Sethi, S, 2010) |
| "In adenine-induced chronic renal failure rats, the protective effects of these Chinese herbs were of a significant nature." | 1.36 | Protection of Chinese herbs against adenine-induced chronic renal failure in rats. ( Guo, H; Han, B; Liu, Y; Tong, Y, 2010) |
| " When implementing HAART, physicians should be aware of and monitor potential patient misunderstanding of instructions on dosage and administration and for possible complications in medicinal combinations and potential side effects." | 1.35 | [A case of acute renal failure involving high amounts of tenofovir after HAART start]. ( Kasahara, K; Konishi, M; Maeda, K; Mikasa, K; Nakagawa, C; Uno, K; Yonekawa, S; Yoshimoto, E, 2008) |
| "We performed a cohort study of 290 chronic hepatitis B patients: 145 patients treated with 10 mg ADV and 145 patients unexposed to ADV at two community clinics, who were matched for age (+/-10 years), sex, and baseline eGFR." | 1.35 | Renal dysfunction in chronic hepatitis B patients treated with adefovir dipivoxil. ( Garcia, RT; Ha, NB; Levitt, BS; Nguyen, HA; Nguyen, KK; Nguyen, MH; Trinh, HN; Vu, AA, 2009) |
| " Third, oral adenine dosing for induction of hyperphosphataemia and validation as a model using Sev were examined." | 1.35 | Comparison of chronic renal failure rats and modification of the preparation protocol as a hyperphosphataemia model. ( Mizukami, K; Okada, M; Terai, K, 2008) |
| "However, in chronic renal failure (CRF), serum 1,25(OH)(2)D and Pi levels are often abnormal." | 1.33 | Nicotinamide prevents the development of hyperphosphataemia by suppressing intestinal sodium-dependent phosphate transporter in rats with adenine-induced renal failure. ( Eto, N; Miyata, Y; Ohno, H; Yamashita, T, 2005) |
| "Adenine-treated rats showed marked elevations of serum phosphorus, PTH and FGF23 levels associated with parathyroid hyperplasia and aortic calcification." | 1.33 | [Effects of intermittent treatment with sevelamer hydrochloride on parathyroid hyperplasia and vascular calcification in rats with chronic kidney disease]. ( Abe, M; Kobayashi, N; Miyata, S; Nagano, N; Wada, M; Wakita, S, 2005) |
| "The adenine-treated rats were divided into the following 3 groups, that is, the group experienced no treatment (control), the group given our Chinese herbal medicine (HAO), and the group given vitamin D3 (VD3) medication." | 1.33 | Effects of the Chinese herbal medicine based on Hachimi-jio-gan in male rats with the adenine-induced osteopenia. ( Gao, M; Guo, L; Guo, Y; Ishida, T; Kanehara, M; Ogirima, T; Tano, K; Wang, X; Zhang, Y, 2005) |
| "The rats with chronic renal failure caused by adenine were divided into 3 groups randomly:the control group (fed with 10 mL water /kg per day), Coated Aldehyde Oxystarch (CAO) group (fed with 20 g CAO /kg and 10 mL water /kg per day) and CLUAs + CAO group (fed with 20 g CAO /kg and 10 mL CLUAs /kg per day) in which CAO was used to absorb the ammonia produced from urea." | 1.32 | [The preparation and application of cross-linked urease aggregates]. ( Dong, XY; Xia, SW, 2003) |
| "The model of chronic renal failure was made by feeding rats with food containing 0." | 1.30 | [Effects of Chinese patent medicine tongfugushen on adenine-induced chronic renal failure in rats]. ( Chen, J; Chen, Y; Deng, H; Yu, A, 1999) |
| "This is the first report of recurrence of the microcrystalline nephritis in a kidney transplant with subsequent loss of allograft function." | 1.29 | Chronic renal failure secondary to 2,8-dihydroxyadenine deposition: the first report of recurrence in a kidney transplant. ( Daudon, M; Deland, E; Gagné, ER; Nawar, T; Noël, LH, 1994) |
| "The effect of adenine-induced chronic renal failure on the male reproductive system was studied using male Wistar rats." | 1.29 | Reproductive insufficiency in the male rat with adenine-induced chronic renal failure. ( Adachi, Y; Nakada, T; Sasagawa, I, 1993) |
| "The adenine-fed chronic renal failure group of rats had a reduced renal blood flow of between 30 and 75%, and glomerular filtration rate of approximately 20%, compared to the sham controls." | 1.28 | The action of atriopeptin III on renal function in two models of chronic renal failure in the rat. ( Johns, EJ; Rutkowski, B, 1990) |
| "Methylguanidine (MG) was intraperitoneally administered to both normal rats and those given adenine, and MG levels in the serum, liver, kidney, muscle, brain and urine were compared." | 1.28 | Variations in the distribution of methylguanidine with the progression of renal failure after methylguanidine loading. ( Fujitsuka, N; Oura, H; Yokozawa, T, 1989) |
| " The toxic effects are discussed on the basis of these results." | 1.28 | Comparison of toxic effects of methylguanidine, guanidinosuccinic acid and creatinine in rats with adenine-induced chronic renal failure. ( Mo, ZL; Oura, H; Yokozawa, T, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (6.80) | 18.7374 |
| 1990's | 20 (13.61) | 18.2507 |
| 2000's | 26 (17.69) | 29.6817 |
| 2010's | 76 (51.70) | 24.3611 |
| 2020's | 15 (10.20) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, S | 2 |
| Manabe, E | 1 |
| Dai, Y | 1 |
| Ishihara, M | 1 |
| Tsujino, T | 1 |
| Samynathan, R | 1 |
| Subramanian, U | 1 |
| Venkidasamy, B | 1 |
| Shariati, MA | 1 |
| Chung, IM | 1 |
| Thiruvengadam, M | 1 |
| Chen, R | 1 |
| Xu, L | 2 |
| Zhang, X | 10 |
| Sun, G | 1 |
| Zeng, W | 1 |
| Sun, X | 2 |
| Hamdy, MM | 1 |
| Abdel-Rahman, MS | 1 |
| Badary, DM | 1 |
| Sabra, MS | 1 |
| Tölle, M | 1 |
| Henkel, C | 1 |
| Herrmann, J | 1 |
| Daniel, C | 1 |
| Babic, M | 1 |
| Xia, M | 1 |
| Schulz, AM | 1 |
| Amann, K | 1 |
| van der Giet, M | 1 |
| Schuchardt, M | 1 |
| Khattri, RB | 1 |
| Kim, K | 1 |
| Anderson, EM | 1 |
| Fazzone, B | 1 |
| Harland, KC | 1 |
| Hu, Q | 1 |
| Palzkill, VR | 1 |
| Cort, TA | 1 |
| O'Malley, KA | 1 |
| Berceli, SA | 1 |
| Scali, ST | 1 |
| Ryan, TE | 1 |
| Sidman, EF | 1 |
| Ondrush, NM | 1 |
| Partosh, D | 3 |
| Sherman, EM | 3 |
| Eckardt, PA | 3 |
| Unger, N | 3 |
| Montalvo, S | 3 |
| Sharma, K | 1 |
| Zhang, G | 2 |
| Hansen, J | 1 |
| Bjornstad, P | 1 |
| Lee, HJ | 1 |
| Menon, R | 1 |
| Hejazi, L | 1 |
| Liu, JJ | 1 |
| Franzone, A | 1 |
| Looker, HC | 1 |
| Choi, BY | 1 |
| Fernandez, R | 1 |
| Venkatachalam, MA | 1 |
| Kugathasan, L | 1 |
| Sridhar, VS | 1 |
| Natarajan, L | 1 |
| Zhang, J | 5 |
| Sharma, VS | 1 |
| Kwan, B | 1 |
| Waikar, SS | 1 |
| Himmelfarb, J | 1 |
| Tuttle, KR | 1 |
| Kestenbaum, B | 1 |
| Fuhrer, T | 1 |
| Feldman, HI | 1 |
| de Boer, IH | 1 |
| Tucci, FC | 1 |
| Sedor, J | 1 |
| Heerspink, HL | 1 |
| Schaub, J | 1 |
| Otto, EA | 1 |
| Hodgin, JB | 1 |
| Kretzler, M | 1 |
| Anderton, CR | 1 |
| Alexandrov, T | 1 |
| Cherney, D | 1 |
| Lim, SC | 1 |
| Nelson, RG | 1 |
| Gelfond, J | 1 |
| Iyengar, R | 1 |
| Drexler, Y | 1 |
| Fornoni, A | 1 |
| Hou, G | 1 |
| Jin, M | 1 |
| Ye, Z | 1 |
| Huang, Q | 1 |
| Ye, M | 1 |
| Walensky, RP | 1 |
| Horn, T | 1 |
| McCann, NC | 1 |
| Freedberg, KA | 1 |
| Paltiel, AD | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 4 |
| Wang, J | 8 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 5 |
| Zhang, Q | 5 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 7 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 5 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 4 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 2 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 5 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 3 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 3 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HBV Viral Suppression by Entecavir in Adefovir Partial Responders[NCT00704106] | 60 participants (Actual) | Observational | 2008-05-31 | Completed | |||
| EuroSIDA Prospective Observational Cohort Study on Clinical and Virological Outcome of European Patients Infected With HIV[NCT02699736] | 23,000 participants (Actual) | Observational [Patient Registry] | 1994-01-31 | Enrolling by invitation | |||
| Effectiveness of Chinese Medicine on Deferring Dialysis Initiation for Stage 5 Chronic Kidney Disease[NCT02194946] | Phase 1/Phase 2 | 875 participants (Anticipated) | Interventional | 2014-07-31 | Active, not recruiting | ||
| Potential Role of Gum Arabic as Antioxidant and Anti-inflammatory Agent in Hemodialysis Patients[NCT03214692] | 50 participants (Anticipated) | Interventional | 2017-07-31 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for adenine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
How to manage HIV-infected patients with chronic kidney disease in the HAART era.
Topics: Adenine; Albuminuria; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Black People; Cystatin | 2012 |
The use of biomarkers for assessing HAART-associated renal toxicity in HIV-infected patients.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiretroviral Therapy, Highly Active; Biomarkers; Crea | 2012 |
[Impact of resistance to analogue antivirals and therapeutic strategies in situations of dialysis, kidney transplantation, vasculitis, and preemptive treatments in immunosuppressed patients].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis B; Hepatitis | 2006 |
HIV-1 infection and the kidney: an evolving challenge in HIV medicine.
Topics: Acute Disease; Acute Kidney Injury; Adenine; AIDS-Associated Nephropathy; Angiotensin-Converting Enz | 2007 |
[Adenine phosphoribosyltransferase(APRT) deficiency].
Topics: Adenine; Adenine Phosphoribosyltransferase; Alleles; Allopurinol; Heterozygote; Homozygote; Humans; | 1996 |
[Phosphoribosyltransferase (APRT) deficiency--molecular and clinical aspects of dihydroxyadeninuria].
Topics: Adenine; Adenine Phosphoribosyltransferase; Humans; Kidney Failure, Chronic; Purine-Pyrimidine Metab | 1998 |
2,8-dihydroxyadenine urolithiasis: report of a case first diagnosed after renal transplant.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adult; Female; Humans; Kidney Calculi; Kidney Failure, C | 1988 |
2 trials available for adenine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
[Renal replacement therapy results in correction of plasma and erythrocyte adenine nucleotide abnormalities in patients with chronic renal failure].
Topics: Adenine; Adenosine Triphosphate; Adult; Aged; Erythrocytes; Erythropoietin; Female; Humans; Kidney F | 2001 |
138 other studies available for adenine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Juzentaihoto improves adenine-induced chronic renal failure in BALB/c mice via suppression of renal fibrosis and inflammation.
Topics: Adenine; Administration, Oral; Animals; Disease Models, Animal; Disease Progression; Drugs, Chinese | 2022 |
S-Allylcysteine (SAC) Exerts Renoprotective Effects via Regulation of TGF- β1/Smad3 Pathway Mediated Matrix Remodeling in Chronic Renal Failure.
Topics: Adenine; Aged; Animals; Cysteine; Fibrosis; Humans; Kidney Failure, Chronic; Rats; Rats, Wistar; Ren | 2022 |
Protective effect and mechanism of Shenkang injection on adenine-induced chronic renal failure in rats.
Topics: Adenine; Animals; Drugs, Chinese Herbal; Fibrosis; Kidney; Kidney Failure, Chronic; Rats; Rats, Spra | 2022 |
Effects of furosemide and tadalafil in both conventional and nanoforms against adenine-induced chronic renal failure in rats.
Topics: Adenine; Animals; Caspase 3; Furosemide; Humans; Kidney Failure, Chronic; Rats; Renal Insufficiency, | 2022 |
Uremic mouse model to study vascular calcification and "inflamm-aging".
Topics: Adenine; Aging; Animals; Disease Models, Animal; Inflammation; Kidney Failure, Chronic; Mice; Rats; | 2022 |
Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arteriovenous Fistula; Arterioven | 2022 |
Utilization of bictegravir/emtricitabine/tenofovir alafenamide in patients with end-stage renal disease on hemodialysis.
Topics: Adenine; Anti-HIV Agents; Drug Combinations; Emtricitabine; Heterocyclic Compounds, 3-Ring; Heterocy | 2023 |
Bictegravir/emtricitabine/tenofovir alafenamide in a virologically suppressed adult with HIV and end-stage renal disease on chronic peritoneal dialysis: A case report.
Topics: Adenine; Adult; Anti-HIV Agents; Drug Combinations; Emtricitabine; HIV Infections; Humans; Kidney Fa | 2023 |
Bictegravir/emtricitabine/tenofovir alafenamide in a virologically suppressed adult with HIV and end-stage renal disease on chronic peritoneal dialysis: A case report.
Topics: Adenine; Adult; Anti-HIV Agents; Drug Combinations; Emtricitabine; HIV Infections; Humans; Kidney Fa | 2023 |
Bictegravir/emtricitabine/tenofovir alafenamide in a virologically suppressed adult with HIV and end-stage renal disease on chronic peritoneal dialysis: A case report.
Topics: Adenine; Adult; Anti-HIV Agents; Drug Combinations; Emtricitabine; HIV Infections; Humans; Kidney Fa | 2023 |
Bictegravir/emtricitabine/tenofovir alafenamide in a virologically suppressed adult with HIV and end-stage renal disease on chronic peritoneal dialysis: A case report.
Topics: Adenine; Adult; Anti-HIV Agents; Drug Combinations; Emtricitabine; HIV Infections; Humans; Kidney Fa | 2023 |
Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients.
Topics: Adenine; Animals; Biomarkers; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic N | 2023 |
Adenine crosses the biomarker bridge: from 'omics to treatment in diabetic kidney disease.
Topics: Adenine; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Kidney; Kidney Failu | 2023 |
Ameliorate effects of soybean soluble polysaccharide on adenine-induced chronic renal failure in mice.
Topics: Adenine; Animals; Glycine max; Kidney Failure, Chronic; Male; Mice; Polysaccharides | 2020 |
Comparative Pricing of Branded Tenofovir Alafenamide-Emtricitabine Relative to Generic Tenofovir Disoproxil Fumarate-Emtricitabine for HIV Preexposure Prophylaxis: A Cost-Effectiveness Analysis.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Cost-Benefit Analysis; Drugs, Generic; Emtricitabine; F | 2020 |
Fibrosis regression is induced by AdhMMP8 in a murine model of chronic kidney injury.
Topics: Adenine; Adenoviridae; Animals; Disease Models, Animal; Fibrosis; Gene Expression Regulation; HEK293 | 2020 |
Antioxidation, anti-inflammation and anti-fibrosis effect of phosphorylated polysaccharides from Pleurotus djamor mycelia on adenine-induced chronic renal failure mice.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Antioxidants; Dietary Supplements; Disease Models, Anima | 2021 |
Parathyroid Hormone Induces Transition of Myofibroblasts in Arteriovenous Fistula and Increases Maturation Failure.
Topics: Adenine; Aged; Animals; Arteriovenous Shunt, Surgical; Biomarkers; Cell Culture Techniques; Disease | 2021 |
Ibrutinib therapy for lymphoplasmacytic lymphoma.
Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Antineoplastic Agents; | 2017 |
Quercetin Attenuates Vascular Calcification through Suppressed Oxidative Stress in Adenine-Induced Chronic Renal Failure Rats.
Topics: Adenine; Alkaline Phosphatase; Animals; Aorta; Biomarkers; Calcium; Kidney; Kidney Failure, Chronic; | 2017 |
PA21, a novel phosphate binder, improves renal osteodystrophy in rats with chronic renal failure.
Topics: Adenine; Animals; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Models, Animal; Dose-Res | 2017 |
Renoprotective effect of Chinese chive polysaccharides in adenine-induced chronic renal failure.
Topics: Adenine; Animals; Antioxidants; Blood Urea Nitrogen; Chive; Creatinine; Humans; Inflammation; Kidney | 2018 |
Erhuang Formula ameliorates renal damage in adenine-induced chronic renal failure rats via inhibiting inflammatory and fibrotic responses.
Topics: Adenine; Animals; Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Creatinine; Drugs, Chin | 2017 |
Successful treatment with tenofovir alafenamide of a HIV/hepatitis B virus coinfected patient with HIV and hepatitis B virus drug resistance, end-stage renal disease on haemodialysis.
Topics: Adenine; Adult; Alanine; Antiviral Agents; Coinfection; Drug Resistance, Viral; Female; Hepatitis B, | 2017 |
Protective effects of Salvia miltiorrhiza on adenine-induced chronic renal failure by regulating the metabolic profiling and modulating the NADPH oxidase/ROS/ERK and TGF-β/Smad signaling pathways.
Topics: Adenine; Animals; Biomarkers; Cell Line; Extracellular Signal-Regulated MAP Kinases; Gene Expression | 2018 |
A novel approach to adenine-induced chronic kidney disease associated anemia in rodents.
Topics: Adenine; Anemia; Animals; Blood Urea Nitrogen; Creatinine; Dose-Response Relationship, Drug; Erythro | 2018 |
A rat model of SHPT with bone abnormalities in CKD induced by adenine and a high phosphorus diet.
Topics: Adenine; Animals; Bone and Bones; Bone Density; Bone Diseases; Bone Diseases, Metabolic; Diet; Disea | 2018 |
Magnesium Citrate Protects Against Vascular Calcification in an Adenine-induced Chronic Renal Failure Rat Model.
Topics: Actins; Adenine; Alkaline Phosphatase; Animals; Aorta; Aortic Diseases; Calcium; Cardiovascular Agen | 2018 |
Adenine-Induced Chronic Renal Failure in Rats: A Model of Chronic Renocardiac Syndrome with Left Ventricular Diastolic Dysfunction but Preserved Ejection Fraction.
Topics: Adenine; Animals; Apoptosis; Cardio-Renal Syndrome; Disease Models, Animal; Heart Failure, Diastolic | 2018 |
Omega-3 polyunsaturated fatty acids alleviate adenine-induced chronic renal failure via regulating ROS production and TGF-β/SMAD pathway.
Topics: Adenine; Animals; Blood Urea Nitrogen; Creatinine; Fatty Acids, Omega-3; Glutathione; Kidney; Kidney | 2018 |
Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2.
Topics: Adenine; Animals; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Gene | 2019 |
Renoprotective Effect of
Topics: Adenine; Animals; Body Weight; Disease Models, Animal; Kidney Failure, Chronic; Laminaria; Male; Mic | 2019 |
Comparison of the Effects of Indobufen and Warfarin in a Rat Model of Adenine-Induced Chronic Kidney Disease.
Topics: Adenine; Animals; Anticoagulants; China; Disease Models, Animal; Fibrosis; Isoindoles; Kidney; Kidne | 2019 |
Diosgenin attenuates vascular calcification in chronic renal failure rats.
Topics: Adenine; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aorta; Biomarkers; Calcium; Catala | 2013 |
Effect of a magnesium-based phosphate binder on medial calcification in a rat model of uremia.
Topics: Acetates; Adenine; Animals; Aortic Diseases; Bone Morphogenetic Protein 2; Calcium; Calcium Compound | 2013 |
Rats with adenine-induced chronic renal failure develop low-renin, salt-sensitive hypertension and increased aortic stiffness.
Topics: Adenine; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Arterial Pressure; Benzimidazoles; | 2013 |
Urinary metabonomic study of the surface layer of Poria cocos as an effective treatment for chronic renal injury in rats.
Topics: Adenine; Animals; Biomarkers; Chromatography, High Pressure Liquid; Cocos; Diuretics; Drugs, Chinese | 2013 |
Changes in B-group vitamin status in adenine-induced chronic renal failure rats.
Topics: Adenine; Animals; Diet; Kidney Failure, Chronic; Male; Organ Specificity; Rats; Rats, Wistar; Vitami | 2013 |
PA21, a new iron-based noncalcium phosphate binder, prevents vascular calcification in chronic renal failure rats.
Topics: Adenine; Animals; Aorta; Blood Pressure; Calcium; Calcium Carbonate; Ferric Compounds; Fibroblast Gr | 2013 |
Nephroprotective effects of Isaria felina in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Ascomycota; Biological Products; Blood Urea Nitrogen; Cordyceps; Creatinine; Disea | 2013 |
Increased risk of dialysis and end-stage renal disease among HIV patients in Denmark compared with the background population.
Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Cohort Studies; Comorbidity; Denmark; Female; H | 2014 |
Exploration of novel predictive markers in rat plasma of the early stages of chronic renal failure.
Topics: Adenine; Adenosine; Animals; Biomarkers; Chromatography, Liquid; Cresols; Early Diagnosis; Glycochol | 2014 |
The effect of activated charcoal on adenine-induced chronic renal failure in rats.
Topics: Adenine; Animals; Body Weight; Charcoal; Kidney Failure, Chronic; Male; Organ Size; Rats; Rats, Wist | 2014 |
High-NaCl diet impairs dynamic renal blood flow autoregulation in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Baroreflex; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Hemodynamics; | 2014 |
Anemia in adenine-induced chronic renal failure and the influence of treatment with gum acacia thereon.
Topics: Adenine; Anemia; Animals; Gum Arabic; Kidney Failure, Chronic; Male; Phytotherapy; Random Allocation | 2014 |
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Topics: Actins; Adenine; Alkaline Phosphatase; Animals; Aorta, Abdominal; Aortic Diseases; Bone Morphogeneti | 2014 |
Chinese herbal medicine Shenqi Detoxification Granule inhibits fibrosis in adenine induced chronic renal failure rats.
Topics: Adenine; Albumins; Animals; Blood Urea Nitrogen; Cholesterol; Connective Tissue Growth Factor; Creat | 2014 |
Renal and myocardial histopathology and morphometry in rats with adenine - induced chronic renal failure: influence of gum acacia.
Topics: Adenine; Animals; Body Weight; Gum Arabic; Kidney; Kidney Failure, Chronic; Male; Myocardium; Organ | 2014 |
High-mobility group box-1 protein in adenine-induced chronic renal failure and the influence of gum arabic thereon.
Topics: Adenine; Animals; Biomarkers; Creatinine; Disease Models, Animal; Gum Arabic; HMGB1 Protein; Indican | 2015 |
Vascular calcification is coupled with phenotypic conversion of vascular smooth muscle cells through Klf5-mediated transactivation of the Runx2 promoter.
Topics: Adenine; Animals; Blotting, Western; Calcinosis; Cells, Cultured; Core Binding Factor Alpha 1 Subuni | 2014 |
Phosphate binders prevent phosphate-induced cellular senescence of vascular smooth muscle cells and vascular calcification in a modified, adenine-based uremic rat model.
Topics: Adenine; Animal Feed; Animals; Calcinosis; Calcium Carbonate; Cellular Senescence; Disease Models, A | 2015 |
Alteration of the Intestinal Environment by Lubiprostone Is Associated with Amelioration of Adenine-Induced CKD.
Topics: Adenine; Alprostadil; Animals; Chloride Channel Agonists; Disease Progression; Drug Evaluation, Prec | 2015 |
Chronic kidney disease induced by adenine: a suitable model of growth retardation in uremia.
Topics: Adenine; Animals; Disease Models, Animal; Female; Growth; Growth Disorders; Growth Plate; Kidney; Ki | 2015 |
Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Animals; Comet Assay; Deoxyguanosine; DNA Damage; Guanine; Gua | 2015 |
Citrate Attenuates Adenine-Induced Chronic Renal Failure in Rats by Modulating the Th17/Treg Cell Balance.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Blood Urea Nitrogen; Cell Survival; Citric Acid; Creatin | 2016 |
Sodium Citrate Inhibits Endoplasmic Reticulum Stress in Rats with Adenine-Induced Chronic Renal Failure.
Topics: Activating Transcription Factor 6; Adenine; Animals; Blood Urea Nitrogen; Buffers; Citrates; Collage | 2015 |
Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification.
Topics: Adenine; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Calcitriol; Cells, Cultured; C | 2016 |
Prolonged Pulmonary Exposure to Diesel Exhaust Particles Exacerbates Renal Oxidative Stress, Inflammation and DNA Damage in Mice with Adenine-Induced Chronic Renal Failure.
Topics: Adenine; Animals; Antioxidants; Blood Pressure; Body Weight; Catalase; Creatinine; DNA Damage; Femal | 2016 |
Bone marrow mesenchymal stromal cells ameliorate angiogenesis and renal damage via promoting PI3k-Akt signaling pathway activation in vivo.
Topics: Adenine; Animals; Bone Marrow Cells; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney | 2016 |
Biodegradable Magnesium (Mg) Implantation Does Not Impose Related Metabolic Disorders in Rats with Chronic Renal Failure.
Topics: Absorbable Implants; Adenine; Animals; Disease Models, Animal; Kidney; Kidney Failure, Chronic; Live | 2016 |
Adenine-induced chronic renal failure in rats decreases aortic relaxation rate and alters expression of proteins involved in vascular smooth muscle calcium handling.
Topics: Adenine; Animals; Aorta, Thoracic; Blotting, Western; Calcium; Disease Models, Animal; Kidney Failur | 2016 |
2,8-Dihydroxyadenine Nephropathy Identified as Cause of End-Stage Renal Disease After Renal Transplant.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adult; Allopurinol; Biomarkers; Biopsy; Enzyme Inhibitor | 2017 |
A highly reproducible mice model of chronic kidney disease: Evidences of behavioural abnormalities and blood-brain barrier disruption.
Topics: Adenine; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Creatinine; Diet; Disease Models, An | 2016 |
[A case of acute renal failure involving high amounts of tenofovir after HAART start].
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; HIV Infections; Humans; Kidney Fail | 2008 |
[Effect of shenshuaining dispersible tablets on the levels of NO, NOS, SOD and MDA in kidney of chronic renal failure rats].
Topics: Adenine; Animals; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Female; Kidney; | 2008 |
Spectrum of chronic kidney disease in HIV-infected patients.
Topics: Adenine; Adult; Age Factors; AIDS-Associated Nephropathy; Analysis of Variance; Anti-HIV Agents; Fem | 2009 |
Possibilities and limits of X-ray microtomography for in vivo and ex vivo detection of vascular calcifications.
Topics: Adenine; Animals; Aorta; Aortic Diseases; Aortography; Calcinosis; Calcium; Disease Models, Animal; | 2009 |
Renal dysfunction in chronic hepatitis B patients treated with adefovir dipivoxil.
Topics: Adenine; Adult; Aged; Antiviral Agents; Cohort Studies; Creatinine; Female; Glomerular Filtration Ra | 2009 |
Crystalline nephropathy due to 2,8-dihydroxyadeninuria: an under-recognized cause of irreversible renal failure.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adult; Allopurinol; Crystallization; Diagnosis, Differen | 2010 |
[Effects of Shenqi Jiedu Decoction on expressions of transforming growth factor-beta1, smad2 and smad3 in renal tissues of rats with chronic renal failure induced by adenine].
Topics: Adenine; Animals; Drugs, Chinese Herbal; Kidney Failure, Chronic; Male; Phytotherapy; Rats; Rats, Wi | 2010 |
Treatment with NZ-419 (5-Hydroxy-1-methylimidazoline-2,4-dione), a novel intrinsic antioxidant, against the progression of chronic kidney disease at stages 3 and 4 in rats.
Topics: Adenine; Administration, Oral; Animals; Antioxidants; Creatinine; Disease Models, Animal; Disease Pr | 2010 |
Chondrocyte rather than osteoblast conversion of vascular cells underlies medial calcification in uremic rats.
Topics: Adenine; Animals; Aortic Diseases; Biomarkers; Calcinosis; Calcium; Cell Transdifferentiation; Chond | 2010 |
Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patients.
Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Disease Progression; Epidemiologic Methods; Fem | 2010 |
[Effects of compound Centella asiatica enema on kidneys coefficient, electrolytes and blood in chronic renal failure rats].
Topics: Adenine; Animals; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Electrolytes; Er | 2010 |
NADPH oxidase activity is associated with cardiac osteopontin and pro-collagen type I expression in uremia.
Topics: Adenine; Animals; Blotting, Western; Cardiovascular Diseases; Catalase; Collagen Type I; Diet, Prote | 2011 |
Motor and behavioral changes in rats with adenine-induced chronic renal failure: influence of acacia gum treatment.
Topics: Adenine; Animals; Body Weight; Creatinine; Depression; Drinking; Gum Arabic; Kidney Failure, Chronic | 2011 |
HIV-2 infection, end-stage renal disease and protease inhibitor intolerance: which salvage regimen?
Topics: Adenine; Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV-2; Humans; Kidney Fa | 2011 |
Protection of Chinese herbs against adenine-induced chronic renal failure in rats.
Topics: Adenine; Albuminuria; Animals; Blood Urea Nitrogen; China; Creatinine; Drugs, Chinese Herbal; Kidney | 2010 |
Effect of Acacia gum on blood pressure in rats with adenine-induced chronic renal failure.
Topics: Acacia; Adenine; Animals; Antihypertensive Agents; Blood Pressure; Gum Arabic; Humans; Kidney Failur | 2011 |
Vascular calcification is associated with cortical bone loss in chronic renal failure rats with and without ovariectomy: the calcification paradox.
Topics: Adenine; Animals; Aorta; Body Weight; Bone and Bones; Calcinosis; Disease Progression; Female; Kidne | 2011 |
Serum metabonomics study of adenine-induced chronic renal failure in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.
Topics: Adenine; Animals; Biomarkers; Chromatography, Liquid; Creatinine; Kidney Failure, Chronic; Lysophosp | 2012 |
Metanephros transplantation inhibits the progression of vascular calcification in rats with adenine-induced renal failure.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Adenine; Animals; Aorta, Thoracic; Calcitriol; Calcium; Cr | 2012 |
Effect and mechanism of fucoidan derivatives from Laminaria japonica in experimental adenine-induced chronic kidney disease.
Topics: Adenine; Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Kidney; Kidney Failure, Chronic; La | 2012 |
Urinary metabonomics study on biochemical changes in an experimental model of chronic renal failure by adenine based on UPLC Q-TOF/MS.
Topics: Adenine; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Kidney Failure, Chro | 2012 |
Association of tenofovir exposure with kidney disease risk in HIV infection.
Topics: Adenine; Adult; Anti-HIV Agents; Female; Follow-Up Studies; Glomerular Filtration Rate; HIV Infectio | 2012 |
Vascular function in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Heart Rate; Kidney Failure | 2012 |
Effect of ergosta-4,6,8(14),22-tetraen-3-one (ergone) on adenine-induced chronic renal failure rat: a serum metabonomic study based on ultra performance liquid chromatography/high-sensitivity mass spectrometry coupled with MassLynx i-FIT algorithm.
Topics: Adenine; Animals; Aspartic Acid; Cholestenones; Chromatography, High Pressure Liquid; Creatinine; Do | 2012 |
Application of faecal metabonomics on an experimental model of tubulointerstitial fibrosis by ultra performance liquid chromatography/high-sensitivity mass spectrometry with MS(E) data collection technique.
Topics: Adenine; Animals; Biomarkers; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; F | 2012 |
Increased time exposure to tenofovir is associated with a greater decrease in estimated glomerular filtration rate in HIV patients with kidney function of less than 60 ml/min/1.73 m2.
Topics: Adenine; Anti-HIV Agents; Female; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Failure | 2012 |
Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats.
Topics: Acetaminophen; Adenine; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antioxidants; Disea | 2012 |
Comparative efficacy of three brands of gum acacia on adenine-induced chronic renal failure in rats.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Blood Pressure; Body Weight; D | 2013 |
UPLC-Q-TOF/HSMS/MS(E)-based metabonomics for adenine-induced changes in metabolic profiles of rat faeces and intervention effects of ergosta-4,6,8(14),22-tetraen-3-one.
Topics: Adenine; Animals; Cholestenones; Chromatography, High Pressure Liquid; Discriminant Analysis; Feces; | 2013 |
Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Anti-Bacterial Agents; Body Weight; Gene Expression; Hypoglycemic Agents; Kidney; | 2013 |
Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes.
Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Aristolochic Acids; Carcinogens; Carcinoma, Tr | 2013 |
Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release.
Topics: Adenine; Alkaline Phosphatase; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Autophagy; Au | 2013 |
Effect of gum arabic on oxidative stress and inflammation in adenine-induced chronic renal failure in rats.
Topics: Adenine; Animals; Creatinine; Gum Arabic; Histones; Immunohistochemistry; Inflammation; Interleukin- | 2013 |
[Effects of Chinese patent medicine tongfugushen on adenine-induced chronic renal failure in rats].
Topics: Adenine; Animals; Drug Combinations; Drugs, Chinese Herbal; Female; Kidney Failure, Chronic; Male; P | 1999 |
Pharmacokinetics of tenofovir in haemodialysis.
Topics: Adenine; Anti-HIV Agents; Humans; Kidney Failure, Chronic; Male; Middle Aged; Organophosphonates; Or | 2003 |
Activity of (-)-epigallocatechin 3-O-gallate against oxidative stress in rats with adenine-induced renal failure.
Topics: Adenine; Animals; Antioxidants; Blood Urea Nitrogen; Catechin; Creatinine; Hydroxyl Radical; Kidney | 2004 |
[Influence of Shenshuai Capsule on renal tissue apoptosis of rats with chronic renal failure].
Topics: Adenine; Animals; Apoptosis; Capsules; Drug Combinations; Drugs, Chinese Herbal; fas Receptor; Kidne | 2004 |
Treatment with adefovir dipivoxil in a renal transplant patient with renal insufficiency and lamivudine-resistant hepatitis B infection.
Topics: Adenine; Antiviral Agents; Creatinine; Drug Resistance, Viral; Follow-Up Studies; Hepatitis B; Human | 2005 |
Nicotinamide prevents the development of hyperphosphataemia by suppressing intestinal sodium-dependent phosphate transporter in rats with adenine-induced renal failure.
Topics: Adenine; Animals; Disease Models, Animal; Disease Progression; Intestinal Mucosa; Intestines; Kidney | 2005 |
[The preparation and application of cross-linked urease aggregates].
Topics: Adenine; Animals; Enzyme Stability; Female; Glutaral; Hydrogen-Ion Concentration; Kidney Failure, Ch | 2003 |
Enzymes that hydrolyze adenine nucleotides in chronic renal failure: relationship between hemostatic defects and renal failure severity.
Topics: 5'-Nucleotidase; Adenine; Analysis of Variance; Antigens, CD; Apyrase; Blood Platelets; Creatine; Hu | 2005 |
[Effects of intermittent treatment with sevelamer hydrochloride on parathyroid hyperplasia and vascular calcification in rats with chronic kidney disease].
Topics: Adenine; Animals; Aortic Diseases; Calcinosis; Calcium; Disease Models, Animal; Drug Administration | 2005 |
Effects of the Chinese herbal medicine based on Hachimi-jio-gan in male rats with the adenine-induced osteopenia.
Topics: Adenine; Animals; Bone Density; Drugs, Chinese Herbal; Kidney Failure, Chronic; Male; Osteoporosis; | 2005 |
Somatic mutations of the von Hippel-Lindau disease gene in renal carcinomas occurring in patients with long-term dialysis.
Topics: Adenine; Aged; Base Sequence; Carcinoma; Carcinoma, Renal Cell; Gene Deletion; Guanine; Humans; Kidn | 2007 |
Chronic renal failure among HIV-1-infected patients.
Topics: Adenine; Adult; Aged; Anti-Retroviral Agents; CD4 Lymphocyte Count; Creatinine; Female; Glomerular F | 2007 |
[Study of the Shenshuaining dispersible tablets in treating chronic renal failure rats induced by adenine].
Topics: Adenine; Animals; Blood Urea Nitrogen; Creatinine; Drugs, Chinese Herbal; Erythrocyte Count; Female; | 2007 |
Alteration of mRNA expression of molecules related to iron metabolism in adenine-induced renal failure rats: a possible mechanism of iron deficiency in chronic kidney disease patients on treatment.
Topics: Adenine; Analysis of Variance; Anemia, Iron-Deficiency; Animals; Antimicrobial Cationic Peptides; Di | 2008 |
Comparison of chronic renal failure rats and modification of the preparation protocol as a hyperphosphataemia model.
Topics: Adenine; Administration, Oral; Animals; Blood Urea Nitrogen; Chelating Agents; Creatinine; Diet; Dis | 2008 |
Renal failure due to 2,8-dihydroxyadenine urolithiasis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Child, Preschool; Diet, Vegetarian; Erythro | 1982 |
[2,8-Dihydroxyadeninuria: 2.8-dihydroxyadenine crystals in urinary sediment in patients with adenine-phosphoribosyltransferase deficiency].
Topics: Adenine; Adenine Phosphoribosyltransferase; Child, Preschool; Erythrocytes; Female; Humans; Kidney F | 1982 |
Accelerated purine base salvage--a possible cause of elevated nucleotide pool in the erythrocytes of patients with uraemia.
Topics: Adenine; Adenine Nucleotides; Adenosine; Erythrocyte Aging; Erythrocytes; Humans; Kidney Failure, Ch | 1994 |
[Experimental study in treating chronic renal failure with dry extract and tannins of herba ephedra].
Topics: Adenine; Animals; Drugs, Chinese Herbal; Kidney Failure, Chronic; Male; Methylguanidine; Rats; Rats, | 1994 |
Chronic renal failure secondary to 2,8-dihydroxyadenine deposition: the first report of recurrence in a kidney transplant.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adult; Humans; Kidney Failure, Chronic; Kidney Transplan | 1994 |
Reproductive insufficiency in the male rat with adenine-induced chronic renal failure.
Topics: 17-alpha-Hydroxyprogesterone; Adenine; Androstenedione; Animals; Blood Urea Nitrogen; Creatinine; Fo | 1993 |
Comparison of renal effects of creatinine, creatol and methylguanidine in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Creatinine; Glomerular Filtration Rate; Kidney Failure, Chronic; Kidney Function T | 1993 |
Adenine phosphoribosyltransferase deficiency with renal deposition of 2,8-dihydroxyadenine leading to nephrolithiasis and chronic renal failure.
Topics: Adenine; Adenine Phosphoribosyltransferase; Heterozygote; Humans; Kidney; Kidney Calculi; Kidney Fai | 1993 |
[Experimental study on kidney invigorating and lipid reducing decoction-yishen jiangzhi tang in the treatment of chronic renal failure].
Topics: Adenine; Animals; Drugs, Chinese Herbal; Female; Granuloma, Foreign-Body; Kidney; Kidney Failure, Ch | 1993 |
Recurrence of 2,8-dihydroxyadenine tubulointerstitial lesions in a kidney transplant recipient with a primary presentation of chronic renal failure.
Topics: Adenine; Adenine Phosphoribosyltransferase; Female; Humans; Kidney Failure, Chronic; Kidney Transpla | 1998 |
Evaluation of adenine concentration in plasma of patients with renal failure using improved ultrafiltration technique.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Humans; Kidney Failure, Chronic; Reference | 1998 |
Increased rate of adenine incorporation into adenine nucleotide pool in erythrocytes of patients with chronic renal failure.
Topics: Adenine; Adenosine Triphosphate; Adult; Aged; Carbon Radioisotopes; Erythrocytes; Female; Humans; Hy | 2000 |
Enhancement of nitroglycerin induced blood vessel relaxation in chronic renal failure model rats.
Topics: Adenine; Animals; Aorta; Aryl Hydrocarbon Hydroxylases; Blood Urea Nitrogen; Cyclic GMP; Cytochrome | 1999 |
[Adenine reutilization as a cause of increased ATP concentration in erythrocytes of patients with chronic renal failure].
Topics: Adenine; Adenosine Triphosphate; Adult; Aged; Erythrocytes; Female; Humans; Kidney Failure, Chronic; | 2001 |
Clinical features and genotype of adenine phosphoribosyltransferase deficiency in iceland.
Topics: Acute Kidney Injury; Adenine; Adenine Phosphoribosyltransferase; Adolescent; Adult; Biopsy; Child; C | 2001 |
High plasma adenine concentration in chronic renal failure and its relation to erythrocyte ATP.
Topics: Adenine; Adenosine Triphosphate; Creatinine; Erythrocytes; Female; Humans; Kidney Failure, Chronic; | 2002 |
[Preliminary experimental and clinical study of the treatment of chronic renal insufficiency by granule of yi-qi bu-shen].
Topics: Adenine; Adult; Animals; Blood Urea Nitrogen; Creatinine; Drugs, Chinese Herbal; Female; Humans; Kid | 1992 |
Increase in kidney 8-hydroxydeoxyguanosine level with the progression of renal failure.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Animals; Deoxyguanosine; DNA Damage; Free Radicals; Kidney; Ki | 1992 |
Renal insufficiency secondary to 2,8-dihydroxyadenine urolithiasis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Crystallization; Electron Probe Microanalysis; Humans; K | 1992 |
[Urolithiasis in chronic renal failure with hemodialysis].
Topics: Adenine; Adult; Calcium Oxalate; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Urinary Calc | 1992 |
Potentiating effect of converting enzyme inhibitor captopril to the renal responses of magnesium lithospermate B in rats with adenine-induced renal failure.
Topics: Adenine; Animals; Captopril; Drug Synergism; Drugs, Chinese Herbal; Kidney Failure, Chronic; Male; R | 1991 |
Degradation of adenine nucleotides in the erythrocytes of patients with chronic renal failure.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Erythrocytes; Hum | 1990 |
The action of atriopeptin III on renal function in two models of chronic renal failure in the rat.
Topics: Adenine; Animals; Atrial Natriuretic Factor; Diuresis; Glomerular Filtration Rate; Kidney; Kidney Fa | 1990 |
Variations in the distribution of methylguanidine with the progression of renal failure after methylguanidine loading.
Topics: Adenine; Animals; Guanidines; Kidney Failure, Chronic; Male; Methylguanidine; Rats; Rats, Inbred Str | 1989 |
Comparison of toxic effects of methylguanidine, guanidinosuccinic acid and creatinine in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Creatinine; Guanidines; Kidney Failure, Chronic; Male; Methylguanidine; Rats; Rats | 1989 |
Urinary constituents and renal function in rats administered with adenine.
Topics: Adenine; Animals; Disease Models, Animal; Kidney; Kidney Failure, Chronic; Male; Rats | 1987 |
Distribution of guanidino compounds in rats with chronic renal failure induced by adenine.
Topics: Adenine; Animals; Disease Models, Animal; Guanidines; Kidney Failure, Chronic; Male; Rats | 1987 |
Blood flow in renal tissue, blood pressure, and blood hormone levels in rats with adenine-induced renal failure.
Topics: Adenine; Animals; Blood Pressure; Disease Models, Animal; Hormones; Kidney Failure, Chronic; Male; R | 1987 |
Animal model of adenine-induced chronic renal failure in rats.
Topics: Adenine; Amino Acids; Animals; Atrophy; Creatinine; Disease Models, Animal; Fibrosis; Guanidines; Ho | 1986 |
The uptake of glycine-14C into the adenine and guanine of DNA and insoluble RNA of human leucocytes.
Topics: Adenine; Autoanalysis; Carbon Radioisotopes; Chromatography, Paper; DNA; Female; Glycine; Gout; Guan | 1974 |