adenine has been researched along with Interstitial Nephritis in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adenine phosphoribosyltransferase deficiency in mice or an excessive oral intake of adenine leads to the accumulation of 2,8-dihydroxyadenine (DHA) in renal tubules and that causes progressive renal dysfunction accompanied by interstitial fibrosis." | 7.75 | Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model. ( Aizawa, R; Hori, M; Ozaki, H; Tamura, M, 2009) |
| "Acute interstitial nephritis was observed only in 1 of 19 patients without atazanavir or tenofovir treatment." | 5.34 | Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies. ( Ambuhl, P; Huber, M; Keusch, G; Moch, H; Moddel, M; Opravil, M; Pfammatter, R; Schmid, S; Varga, Z; Wuthrich, RP, 2007) |
| " Here we investigated long-term effects of PHDI treatment in adenine-induced nephropathy as a model for chronic tubulointerstitial nephritis." | 3.91 | Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis. ( Beneke, A; Burzlaff, N; Daniel, C; Eckardt, KU; Goppelt-Struebe, M; Herrmann, M; Jantsch, J; Kalucka, J; Katschinski, DM; Klanke, B; Mayer, M; Palsson, R; Schatz, V; Schley, G; Thorsteinsdottir, M; Weidemann, A; Willam, C, 2019) |
| "The adenine-treated animals exhibited marked azotemia, impaired urinary concentrating capacity, intense tubular and glomerular damage, interstitial inflammation and fibrosis." | 3.79 | Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy. ( Aminzadeh, MA; Nicholas, SB; Norris, KC; Vaziri, ND, 2013) |
| "Adenine overload promotes intratubular crystal precipitation and interstitial nephritis." | 3.79 | NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy. ( Arias, SC; Barlette, GP; Borges, RL; Camara, NO; de Almeida, DC; Fanelli, C; Fujihara, CK; Machado, FG; Malheiros, DM; Okabe, C; Zatz, R, 2013) |
| "Adenine phosphoribosyltransferase deficiency in mice or an excessive oral intake of adenine leads to the accumulation of 2,8-dihydroxyadenine (DHA) in renal tubules and that causes progressive renal dysfunction accompanied by interstitial fibrosis." | 3.75 | Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model. ( Aizawa, R; Hori, M; Ozaki, H; Tamura, M, 2009) |
| "Acute interstitial nephritis was observed only in 1 of 19 patients without atazanavir or tenofovir treatment." | 1.34 | Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies. ( Ambuhl, P; Huber, M; Keusch, G; Moch, H; Moddel, M; Opravil, M; Pfammatter, R; Schmid, S; Varga, Z; Wuthrich, RP, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, H | 1 |
| Zheng, C | 1 |
| Zhu, L | 1 |
| Song, Z | 1 |
| Dai, L | 1 |
| Hu, Q | 1 |
| Wang, L | 1 |
| Chen, Y | 1 |
| Xiong, J | 1 |
| Markóth, C | 1 |
| File, I | 1 |
| Szász, R | 1 |
| Bidiga, L | 1 |
| Balla, J | 1 |
| Mátyus, J | 1 |
| Schley, G | 1 |
| Klanke, B | 1 |
| Kalucka, J | 1 |
| Schatz, V | 1 |
| Daniel, C | 1 |
| Mayer, M | 1 |
| Goppelt-Struebe, M | 1 |
| Herrmann, M | 1 |
| Thorsteinsdottir, M | 1 |
| Palsson, R | 1 |
| Beneke, A | 1 |
| Katschinski, DM | 1 |
| Burzlaff, N | 1 |
| Eckardt, KU | 1 |
| Weidemann, A | 1 |
| Jantsch, J | 1 |
| Willam, C | 1 |
| Aminzadeh, MA | 1 |
| Nicholas, SB | 1 |
| Norris, KC | 1 |
| Vaziri, ND | 2 |
| Okabe, C | 1 |
| Borges, RL | 1 |
| de Almeida, DC | 1 |
| Fanelli, C | 1 |
| Barlette, GP | 1 |
| Machado, FG | 1 |
| Arias, SC | 1 |
| Malheiros, DM | 1 |
| Camara, NO | 3 |
| Zatz, R | 2 |
| Fujihara, CK | 1 |
| Jia, T | 1 |
| Olauson, H | 1 |
| Lindberg, K | 1 |
| Amin, R | 1 |
| Edvardsson, K | 1 |
| Lindholm, B | 1 |
| Andersson, G | 1 |
| Wernerson, A | 1 |
| Sabbagh, Y | 1 |
| Schiavi, S | 1 |
| Larsson, TE | 1 |
| Hamasaki, Y | 1 |
| Doi, K | 1 |
| Maeda-Mamiya, R | 1 |
| Ogasawara, E | 1 |
| Katagiri, D | 1 |
| Tanaka, T | 1 |
| Yamamoto, T | 1 |
| Sugaya, T | 1 |
| Nangaku, M | 1 |
| Noiri, E | 1 |
| Correa-Costa, M | 2 |
| Braga, TT | 2 |
| Felizardo, RJ | 1 |
| Andrade-Oliveira, V | 1 |
| Perez, KR | 1 |
| Cuccovia, IM | 1 |
| Hiyane, MI | 1 |
| da Silva, JS | 1 |
| Hussein, AM | 1 |
| Malek, HA | 1 |
| Saad, MA | 1 |
| Chen, H | 1 |
| Cao, G | 1 |
| Chen, DQ | 1 |
| Wang, M | 1 |
| Zhang, ZH | 1 |
| Mao, JR | 1 |
| Bai, X | 1 |
| Zhao, YY | 1 |
| Tamura, M | 1 |
| Aizawa, R | 1 |
| Hori, M | 1 |
| Ozaki, H | 1 |
| Shpacovitch, V | 1 |
| Mertens, PR | 1 |
| Nozue, H | 1 |
| Kamoda, T | 1 |
| Saitoh, H | 1 |
| Ichikawa, K | 1 |
| Taniguchi, A | 1 |
| Semedo, P | 1 |
| Hayashida, CY | 1 |
| Bechara, LR | 1 |
| Elias, RM | 1 |
| Barreto, CR | 1 |
| Silva-Cunha, C | 1 |
| Hyane, MI | 1 |
| Gonçalves, GM | 1 |
| Brum, PC | 1 |
| Fujihara, C | 1 |
| Pacheco-Silva, A | 1 |
| Zamboni, DS | 1 |
| Dai, CL | 1 |
| Zhu, M | 1 |
| Wang, BP | 1 |
| Guo, F | 1 |
| Zhang, X | 1 |
| Song, WZ | 1 |
| Zhu, TH | 1 |
| Wang, BL | 1 |
| Qiu, MC | 1 |
| Nishijima, T | 1 |
| Yazaki, H | 1 |
| Hinoshita, F | 1 |
| Tasato, D | 1 |
| Hoshimoto, K | 1 |
| Teruya, K | 1 |
| Gatanaga, H | 1 |
| Kikuchi, Y | 1 |
| Oka, S | 1 |
| Schmid, S | 1 |
| Opravil, M | 1 |
| Moddel, M | 1 |
| Huber, M | 1 |
| Pfammatter, R | 1 |
| Keusch, G | 1 |
| Ambuhl, P | 1 |
| Wuthrich, RP | 1 |
| Moch, H | 1 |
| Varga, Z | 1 |
| Fine, DM | 1 |
| Perazella, MA | 1 |
| Lucas, GM | 1 |
| Atta, MG | 1 |
| Brown, HA | 1 |
1 review available for adenine and Interstitial Nephritis
| Article | Year |
|---|---|
Kidney biopsy in HIV: beyond HIV-associated nephropathy.
Topics: Acute Disease; Adenine; AIDS-Associated Nephropathy; Anti-HIV Agents; Antiretroviral Therapy, Highly | 2008 |
18 other studies available for adenine and Interstitial Nephritis
| Article | Year |
|---|---|
Contribution of TFEB-mediated autophagy to tubulointerstitial fibrosis in mice with adenine-induced chronic kidney disease.
Topics: Adenine; Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line; | 2021 |
Ibrutinib-induced acute kidney injury via interstitial nephritis.
Topics: Acute Kidney Injury; Adenine; Aged; Cytokines; Glucocorticoids; Humans; Kidney; Leukemia, Prolymphoc | 2021 |
Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Basic Helix-Loop-Helix Transcription Factors; Clodronic | 2019 |
Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy.
Topics: Adenine; Animals; Arachidonate 12-Lipoxygenase; Blotting, Western; Catalase; Chronic Disease; Cycloo | 2013 |
NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Granuloma; Inflammation Mediators; Kidney; Male; | 2013 |
A novel model of adenine-induced tubulointerstitial nephropathy in mice.
Topics: Adenine; Animals; Disease Models, Animal; Fibroblast Growth Factor-23; Mice; Mice, Inbred C57BL; Nep | 2013 |
A 5-hydroxytryptamine receptor antagonist, sarpogrelate, reduces renal tubulointerstitial fibrosis by suppressing PAI-1.
Topics: Adenine; Animals; Cells, Cultured; Disease Models, Animal; Fatty Acid-Binding Proteins; Fibrosis; In | 2013 |
Macrophage trafficking as key mediator of adenine-induced kidney injury.
Topics: Acute Kidney Injury; Adenine; Animals; Chemokine CCL3; Flow Cytometry; Kidney; Macrophages; Mice; Mi | 2014 |
Renoprotective effects of aliskiren on adenine-induced tubulointerstitial nephropathy: possible underlying mechanisms.
Topics: Adenine; Amides; Animals; Apoptosis; Fumarates; Male; Nephritis, Interstitial; Protective Agents; Ra | 2016 |
Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression.
Topics: Adenine; Animals; Aristolochic Acids; Biomarkers; Disease Models, Animal; Disease Progression; Early | 2016 |
Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model.
Topics: Actins; Adenine; Animals; Chemokines; Chemotaxis; Collagen; Cytokines; Disease Models, Animal; Fibro | 2009 |
High mobility group box protein-1 crossing cell borders may incite an inflammatory "tornado" in renal disease.
Topics: Adenine; Animals; Chemokine CCL2; Disease Progression; HMGB1 Protein; Kidney; Macrophages; Mice; Nep | 2010 |
A Japanese boy with adenine phosphoribosyltransferase (APRT) deficiency caused by compound heterozygosity including a novel missense mutation in APRT gene.
Topics: Adenine; Adenine Phosphoribosyltransferase; Asian People; Child, Preschool; Humans; Lithotripsy; Mal | 2011 |
Pivotal role of Toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritis.
Topics: Adenine; Allopurinol; Animals; Diet; Disease Progression; Inflammasomes; Inflammation; Kidney Tubule | 2011 |
Prolonged adefovir therapy associated Fanconi syndrome and interstitial nephritis in hepatitis B.
Topics: Adenine; Drug Administration Schedule; Fanconi Syndrome; Hepatitis B; Humans; Male; Middle Aged; Nep | 2012 |
Drug-induced acute interstitial nephritis mimicking acute tubular necrosis after initiation of tenofovir-containing antiretroviral therapy in patient with HIV-1 infection.
Topics: Acute Disease; Adenine; Aged; Anti-Retroviral Agents; Biopsy; Diagnosis, Differential; HIV Infection | 2012 |
Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies.
Topics: Acute Kidney Injury; Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Female; Fluorescent Antibo | 2007 |
Recurrence of 2,8-dihydroxyadenine tubulointerstitial lesions in a kidney transplant recipient with a primary presentation of chronic renal failure.
Topics: Adenine; Adenine Phosphoribosyltransferase; Female; Humans; Kidney Failure, Chronic; Kidney Transpla | 1998 |