adenine has been researched along with Insulinoma in 2 studies
Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, we show that systemic treatment of insulinoma-bearing mice with PCI-32765 efficiently inhibits Btk, blocks mast cell degranulation, and triggers collapse of tumor vasculature and tumor regression." | 1.37 | Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma. ( Adimoolam, S; Allende, MT; Buggy, JJ; Evan, GI; Kortlever, R; Monclús, HA; Soucek, L; Swigart, LB, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soucek, L | 1 |
| Buggy, JJ | 1 |
| Kortlever, R | 1 |
| Adimoolam, S | 1 |
| Monclús, HA | 1 |
| Allende, MT | 1 |
| Swigart, LB | 1 |
| Evan, GI | 1 |
| Chung, DC | 1 |
| Brand, SJ | 1 |
| Tillotson, LG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short-term Combined Acalabrutinib and Venetoclax Treatment of Newly Diagnosed Patients With CLL at High Risk of Infection and/or Early Treatment, Who do Not Fulfil IWCLL Treatment Criteria.[NCT03868722] | Phase 2/Phase 3 | 212 participants (Anticipated) | Interventional | 2019-10-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for adenine and Insulinoma
| Article | Year |
|---|---|
Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Cell Degranulation; Cell Proliferation; Cell | 2011 |
Mutually exclusive interactions between factors binding to adjacent Sp1 and AT-rich elements regulate gastrin gene transcription in insulinoma cells.
Topics: Adenine; Animals; Base Sequence; Gastrins; Gene Expression Regulation; Humans; Insulinoma; Islets of | 1995 |