adenine has been researched along with Insulin Resistance in 14 studies
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to assess the effect on insulin sensitivity (determined by peripheral glucose uptake using a hyperinsulinaemic euglycaemic clamp) of tenofovir disoproxil fumarate (TDF) administration compared with placebo for 2 weeks in HIV-1-seronegative healthy male volunteers." | 9.14 | The effect of tenofovir disoproxil fumarate on whole-body insulin sensitivity, lipids and adipokines in healthy volunteers. ( Jackson, AG; Moyle, GJ; Randell, PA; Yale, K; Zhong, L, 2010) |
| " Healthy volunteer studies have demonstrated a decrease in glucose disposal associated with dosing with specific antiretrovirals." | 6.75 | Effect of boosted fosamprenavir or lopinavir-based combinations on whole-body insulin sensitivity and lipids in treatment-naive HIV-type-1-positive men. ( Back, DJ; Boffito, M; Jackson, AG; Mandalia, S; Moyle, GJ; Randell, PA; Taylor, J; Tjia, JF, 2010) |
| " The aim of this study was to assess the effect on insulin sensitivity (determined by peripheral glucose uptake using a hyperinsulinaemic euglycaemic clamp) of tenofovir disoproxil fumarate (TDF) administration compared with placebo for 2 weeks in HIV-1-seronegative healthy male volunteers." | 5.14 | The effect of tenofovir disoproxil fumarate on whole-body insulin sensitivity, lipids and adipokines in healthy volunteers. ( Jackson, AG; Moyle, GJ; Randell, PA; Yale, K; Zhong, L, 2010) |
| " To find out whether suppressed autophagy was linked to inflammation we used the autophagy inhibitor, 3-methyladenine, to inhibit autophagy." | 3.78 | Autophagy regulates inflammation in adipocytes. ( Kashiwagi, A; Kondo, M; Kume, S; Kusunoki, C; Maegawa, H; Morino, K; Nishio, Y; Sekine, O; Ugi, S; Uzu, T; Yasuda, M; Yoshizaki, T, 2012) |
| " Healthy volunteer studies have demonstrated a decrease in glucose disposal associated with dosing with specific antiretrovirals." | 2.75 | Effect of boosted fosamprenavir or lopinavir-based combinations on whole-body insulin sensitivity and lipids in treatment-naive HIV-type-1-positive men. ( Back, DJ; Boffito, M; Jackson, AG; Mandalia, S; Moyle, GJ; Randell, PA; Taylor, J; Tjia, JF, 2010) |
| "Insulin resistance is correlated with the progress of albuminuria in diabetic patients, and podocytes are crucial for maintaining the normal function of the glomerular filtration barrier." | 1.43 | Autophagy protects human podocytes from high glucose-induced injury by preventing insulin resistance. ( Chen, L; Li, Z; Wan, Q; Xin, W; Xu, Y; Yu, Y; Zhou, Q, 2016) |
| "Obesity was accompanied by insulin resistance, and 65% reduction (P<0." | 1.34 | Age related obesity-induced shortening of GLUT4 mRNA poly(A) tail length in rat gastrocnemius skeletal muscle. ( Giannocco, G; Machado, UF; Nunes, MT; Seraphim, PM, 2007) |
| "Insulin sensitivity was assessed by homeostasis model assessment (HOMA) index in healthy subjects and hyperinsulinemic euglycemic clamp in type 2 diabetic patients." | 1.31 | Relationship of the tumor necrosis factor-alpha -308 A/G promoter polymorphism with insulin sensitivity and abdominal fat distribution in Japanese patients with type 2 diabetes mellitus. ( Adachi, Y; Araki-Sasaki, R; Furuta, M; Gabazza, EC; Hirata, N; Hori, Y; Ito, K; Katsuki, A; Ohtake, K; Sumida, Y; Tanaka, T; Yano, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jing, YH | 1 |
| Zhang, L | 1 |
| Gao, LP | 1 |
| Qi, CC | 1 |
| Lv, DD | 1 |
| Song, YF | 1 |
| Yin, J | 1 |
| Wang, DG | 1 |
| Spinner, CD | 1 |
| Schulz, S | 1 |
| Bauer, U | 1 |
| Schneider, J | 1 |
| Bobardt, J | 1 |
| Von Werder, A | 1 |
| Schmid, RM | 1 |
| Zink, A | 1 |
| Wolf, E | 1 |
| Iakoubov, R | 1 |
| Luan, B | 1 |
| Sun, C | 1 |
| Kiage, JN | 1 |
| Heimburger, DC | 1 |
| Nyirenda, CK | 1 |
| Wellons, MF | 1 |
| Bagchi, S | 1 |
| Chi, BH | 1 |
| Koethe, JR | 1 |
| Arnett, DK | 1 |
| Kabagambe, EK | 1 |
| Shi, L | 1 |
| Zhang, T | 1 |
| Liang, X | 1 |
| Hu, Q | 1 |
| Huang, J | 1 |
| Zhou, Y | 1 |
| Chen, M | 1 |
| Zhang, Q | 1 |
| Zhu, J | 1 |
| Mi, M | 1 |
| Xin, W | 1 |
| Li, Z | 1 |
| Xu, Y | 1 |
| Yu, Y | 1 |
| Zhou, Q | 1 |
| Chen, L | 1 |
| Wan, Q | 1 |
| Randell, PA | 2 |
| Jackson, AG | 2 |
| Zhong, L | 1 |
| Yale, K | 1 |
| Moyle, GJ | 2 |
| Boffito, M | 1 |
| Back, DJ | 1 |
| Tjia, JF | 1 |
| Taylor, J | 1 |
| Mandalia, S | 1 |
| Yoshizaki, T | 1 |
| Kusunoki, C | 1 |
| Kondo, M | 1 |
| Yasuda, M | 1 |
| Kume, S | 1 |
| Morino, K | 1 |
| Sekine, O | 1 |
| Ugi, S | 1 |
| Uzu, T | 1 |
| Nishio, Y | 1 |
| Kashiwagi, A | 1 |
| Maegawa, H | 1 |
| Rosmond, R | 1 |
| Chagnon, M | 1 |
| Bouchard, C | 1 |
| Björntorp, P | 1 |
| Simeoni, E | 1 |
| Hoffmann, MM | 1 |
| Winkelmann, BR | 1 |
| Ruiz, J | 1 |
| Fleury, S | 1 |
| Boehm, BO | 1 |
| März, W | 1 |
| Vassalli, G | 1 |
| Seraphim, PM | 1 |
| Nunes, MT | 1 |
| Giannocco, G | 1 |
| Machado, UF | 1 |
| Carr, A | 1 |
| Hudson, J | 1 |
| Chuah, J | 1 |
| Mallal, S | 1 |
| Law, M | 1 |
| Hoy, J | 1 |
| Doong, N | 1 |
| French, M | 1 |
| Smith, D | 1 |
| Cooper, DA | 1 |
| Furuta, M | 1 |
| Yano, Y | 1 |
| Ito, K | 1 |
| Gabazza, EC | 1 |
| Katsuki, A | 1 |
| Tanaka, T | 1 |
| Ohtake, K | 1 |
| Hirata, N | 1 |
| Hori, Y | 1 |
| Araki-Sasaki, R | 1 |
| Sumida, Y | 1 |
| Adachi, Y | 1 |
4 trials available for adenine and Insulin Resistance
| Article | Year |
|---|---|
Effects of antiretroviral combination therapies F/TAF, E/C/F/TAF and R/F/TAF on insulin resistance in healthy volunteers: the TAF-IR Study.
Topics: Adenine; Adult; Anti-HIV Agents; Blood Glucose; Body Weight; Drug Combinations; Elvitegravir, Cobici | 2018 |
The effect of tenofovir disoproxil fumarate on whole-body insulin sensitivity, lipids and adipokines in healthy volunteers.
Topics: Adenine; Adipokines; Adult; Anti-HIV Agents; Cholesterol; Cholesterol, LDL; Cross-Over Studies; Drug | 2010 |
Effect of boosted fosamprenavir or lopinavir-based combinations on whole-body insulin sensitivity and lipids in treatment-naive HIV-type-1-positive men.
Topics: Adenine; Adipose Tissue; Adult; Anti-HIV Agents; Blood Glucose; Carbamates; Confidence Intervals; Dr | 2010 |
HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Carnitine; Dideox | 2001 |
10 other studies available for adenine and Insulin Resistance
| Article | Year |
|---|---|
Autophagy plays beneficial effect on diabetic encephalopathy in type 2 diabetes: studies in vivo and in vitro.
Topics: Adenine; Animals; Arcuate Nucleus of Hypothalamus; Autophagy; Blotting, Western; Brain Diseases; Cho | 2017 |
MiR-138-5p affects insulin resistance to regulate type 2 diabetes progression through inducing autophagy in HepG2 cells by regulating SIRT1.
Topics: Adenine; Autophagy; Diabetes Mellitus, Type 2; Disease Progression; Down-Regulation; Glucose; Glycog | 2018 |
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxa | 2013 |
Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Autophagy; Cells, Cultured; Diabetes Mellitus, Type | 2015 |
Autophagy protects human podocytes from high glucose-induced injury by preventing insulin resistance.
Topics: Adenine; Autophagy; Cells, Cultured; Culture Media; Glucose; Humans; Insulin Resistance; Membrane Pr | 2016 |
Autophagy regulates inflammation in adipocytes.
Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Autophagy; Endoplasmic Reticulum Stress; Gene Expression | 2012 |
Increased abdominal obesity, insulin and glucose levels in nondiabetic subjects with a T29C polymorphism of the transforming growth factor-beta1 gene.
Topics: Abdomen; Adenine; Blood Glucose; Fasting; Gene Frequency; Genetic Variation; Guanine; Heterozygote; | 2003 |
Association between the A-2518G polymorphism in the monocyte chemoattractant protein-1 gene and insulin resistance and Type 2 diabetes mellitus.
Topics: Adenine; Aged; Chemokine CCL2; Cohort Studies; Diabetes Mellitus, Type 2; Female; Glucose; Guanine; | 2004 |
Age related obesity-induced shortening of GLUT4 mRNA poly(A) tail length in rat gastrocnemius skeletal muscle.
Topics: Adenine; Adipose Tissue, White; Aging; Animals; Gene Expression Regulation; Glucose Transporter Type | 2007 |
Relationship of the tumor necrosis factor-alpha -308 A/G promoter polymorphism with insulin sensitivity and abdominal fat distribution in Japanese patients with type 2 diabetes mellitus.
Topics: Abdomen; Adenine; Adipose Tissue; Asian People; Body Mass Index; Diabetes Mellitus, Type 2; DNA Prim | 2002 |