adenine and Hypoxia
adenine has been researched along with Hypoxia in 47 studies
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"We measured the changes in pial arteriolar diameter and CSF concentrations of adenosine, inosine, and hypoxanthine during hypoxia in the absence and presence of topically applied dipyridamole (10(-6) M) and erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA; 10(-5) M)." | 7.68 | Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia. ( Meno, JR; Ngai, AC; Winn, HR, 1993) |
"The survival time of rats and hamsters in lethal hypoxia was measured after a sublethal exposure and a normoxia break, at the beginning of which purines were administered intraperitoneally in the following dosages: 25 mg/kg hypoxanthine, 50 mg/kg allopurinol, 25 mg/kg adenine." | 7.68 | Influence of hypoxanthine, allopurinol and adenine on resistance of rats and hamsters to hypobaric hypoxia. ( Brandová, J; Novák, L; Stípek, S; Trojan, S, 1990) |
"After the same period of anoxia 50% of the total pool, comprising adenosine, inosine, hypoxanthine and uric acid in approximately equal proportions, was recovered from the coronary perfusate." | 5.27 | Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development. ( Holliss, DG; Humphrey, SM; Seelye, RN, 1984) |
" Therefore, the aim of our study was to use human colorectal cancer HCT116 cells to explore whether inhibition of autophagy by 3-Methyladenine (3-MA, an autophagy inhibitor) is able to enhance hypoxia-induced apoptosis in vitro." | 3.91 | Inhibition of autophagy by 3-MA promotes hypoxia-induced apoptosis in human colorectal cancer cells. ( Dong, Y; Wu, Y; Xing, CG; Yang, XD; Ye, ZY; Zhao, GL, 2019) |
" Inhibition of autophagy by chloroquine and 3-methyladenine worsened renal ischemia/reperfusion injury, as indicated by renal function, histology, and tubular apoptosis." | 3.76 | Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury. ( Dong, Z; Jiang, M; Liu, K; Luo, J, 2010) |
" We used Langendorff isolated rat heart preparation to test the hypothesis that allopurinol could maintain a level of the adenine nucleotide pool (ATP, ADP, and AMP) that would protect and improve the functional activity of the heart during a period of hypoxia." | 3.71 | Allopurinol enhances adenine nucleotide levels and improves myocardial function in isolated hypoxic rat heart. ( El-Migdadi, F; Farah, H; Khatib, SY, 2001) |
"We measured the changes in pial arteriolar diameter and CSF concentrations of adenosine, inosine, and hypoxanthine during hypoxia in the absence and presence of topically applied dipyridamole (10(-6) M) and erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA; 10(-5) M)." | 3.68 | Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia. ( Meno, JR; Ngai, AC; Winn, HR, 1993) |
"The effects of 5-amino-4-imidazolecarboxamide riboside (rAICA) on coronary adenosine efflux were examined in blood-free perfused working rat heart preparations subjected to mild (70% O2) and severe hypoxia (45% O2)." | 3.68 | 5-Amino-4-imidazolecarboxamide riboside raises adenosine in perfused hypoxic rat heart. ( Burrier, AC; Jeng, AY; Oei, HH, 1991) |
"The administration of allopurinol significantly increased resistance to repeated hypobaric hypoxia, while hypoxanthine decreased it." | 3.68 | Plasma xanthine oxidase and resistance to hypoxia: effect of purines and alcohol administration. ( Novák, L; Stípek, S; Trojan, S; Zima, T, 1991) |
"The survival time of rats and hamsters in lethal hypoxia was measured after a sublethal exposure and a normoxia break, at the beginning of which purines were administered intraperitoneally in the following dosages: 25 mg/kg hypoxanthine, 50 mg/kg allopurinol, 25 mg/kg adenine." | 3.68 | Influence of hypoxanthine, allopurinol and adenine on resistance of rats and hamsters to hypobaric hypoxia. ( Brandová, J; Novák, L; Stípek, S; Trojan, S, 1990) |
"Renal fibrosis is the final manifestation of chronic kidney disease (CKD) regardless of etiology." | 1.91 | Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model. ( Kim, DA; Kim, M; Kong, KH; Lee, MR; Oh, HJ, 2023) |
" These findings indicate that adenine at 50 microM dosage can restore ATP concentrations to the normoxic range after 60 in of anoxia in the nonworking rat heart while raising the adenine dose to 1 mM inhibited the tissue ATP content." | 1.28 | Dose effects of adenine on myocardial ATP content in the post-anoxic nonworking rat heart. ( Halle, AA; Kang, ES; Mirvis, DM; Sullivan, JM, 1989) |
"After the same period of anoxia 50% of the total pool, comprising adenosine, inosine, hypoxanthine and uric acid in approximately equal proportions, was recovered from the coronary perfusate." | 1.27 | Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development. ( Holliss, DG; Humphrey, SM; Seelye, RN, 1984) |
"[3H]adenine was taken up by a crude hypothalamic synaptosomal fraction and incorporated into mainly nucleotides." | 1.26 | Release of 3H-nucleosides from 3H-adenine labelled hypothalamic synaptosomes. ( Fredholm, BB; Vernet, L, 1979) |
"In can be concluded that anoxia kidney deterioration is associated with a progressive loss of intracellular oxypurine, and a decreasing ability to regenerate adenylates after reoxygenation, which could be prevented by exogenic addition of adenosine." | 1.26 | The postanoxic regeneration of 5'-adenosine nucleotides in rabbit kidney tissue during in vitro perfusion. ( Buhl, MR, 1976) |
Research
Studies (47)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (23.40) | 18.7374 |
1990's | 15 (31.91) | 18.2507 |
2000's | 5 (10.64) | 29.6817 |
2010's | 13 (27.66) | 24.3611 |
2020's | 3 (6.38) | 2.80 |
Authors
Authors | Studies |
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Xu, L | 2 |
Bi, Y | 1 |
Xu, Y | 2 |
Wu, Y | 4 |
Du, X | 1 |
Mou, Y | 1 |
Chen, J | 3 |
Kim, DA | 3 |
Lee, MR | 3 |
Oh, HJ | 3 |
Kim, M | 3 |
Kong, KH | 3 |
Halim, AA | 1 |
Alsayed, B | 1 |
Embarak, S | 1 |
Yaseen, T | 1 |
Dabbous, S | 1 |
Fontaine, O | 1 |
Dueluzeau, R | 1 |
Raibaud, P | 1 |
Chabanet, C | 1 |
Popoff, MR | 1 |
Badoual, J | 1 |
Gabilan, JC | 1 |
Andremont, A | 1 |
Gómez, L | 1 |
Andrés, S | 1 |
Sánchez, J | 1 |
Alonso, JM | 1 |
Rey, J | 1 |
López, F | 1 |
Jiménez, A | 1 |
Yan, Z | 1 |
Zhou, L | 1 |
Zhao, Y | 3 |
Wang, J | 6 |
Huang, L | 2 |
Hu, K | 1 |
Liu, H | 4 |
Wang, H | 3 |
Guo, Z | 1 |
Song, Y | 1 |
Huang, H | 4 |
Yang, R | 1 |
Owen, TW | 1 |
Al-Kaysi, RO | 1 |
Bardeen, CJ | 1 |
Cheng, Q | 1 |
Wu, S | 1 |
Cheng, T | 1 |
Zhou, X | 1 |
Wang, B | 4 |
Zhang, Q | 4 |
Wu, X | 2 |
Yao, Y | 3 |
Ochiai, T | 1 |
Ishiguro, H | 2 |
Nakano, R | 2 |
Kubota, Y | 2 |
Hara, M | 1 |
Sunada, K | 1 |
Hashimoto, K | 1 |
Kajioka, J | 1 |
Fujishima, A | 1 |
Jiao, J | 3 |
Gai, QY | 3 |
Wang, W | 2 |
Zang, YP | 2 |
Niu, LL | 2 |
Fu, YJ | 3 |
Wang, X | 6 |
Yao, LP | 1 |
Qin, QP | 1 |
Wang, ZY | 1 |
Liu, J | 4 |
Aleksic Sabo, V | 1 |
Knezevic, P | 1 |
Borges-Argáez, R | 1 |
Chan-Balan, R | 1 |
Cetina-Montejo, L | 1 |
Ayora-Talavera, G | 1 |
Sansores-Peraza, P | 1 |
Gómez-Carballo, J | 1 |
Cáceres-Farfán, M | 1 |
Jang, J | 1 |
Akin, D | 1 |
Bashir, R | 1 |
Yu, Z | 1 |
Zhu, J | 2 |
Jiang, H | 1 |
He, C | 2 |
Xiao, Z | 1 |
Xu, J | 2 |
Sun, Q | 1 |
Han, D | 1 |
Lei, H | 1 |
Zhao, K | 2 |
Zhu, L | 1 |
Li, X | 5 |
Fu, H | 2 |
Wilson, BK | 1 |
Step, DL | 1 |
Maxwell, CL | 1 |
Gifford, CA | 1 |
Richards, CJ | 1 |
Krehbiel, CR | 1 |
Warner, JM | 1 |
Doerr, AJ | 1 |
Erickson, GE | 1 |
Guretzky, JA | 1 |
Rasby, RJ | 1 |
Watson, AK | 1 |
Klopfenstein, TJ | 1 |
Sun, Y | 4 |
Liu, Z | 3 |
Pham, TD | 1 |
Lee, BK | 1 |
Yang, FC | 1 |
Wu, KH | 1 |
Lin, WP | 1 |
Hu, MK | 1 |
Lin, L | 3 |
Shao, J | 1 |
Sun, M | 1 |
Xu, G | 1 |
Zhang, X | 7 |
Xu, N | 1 |
Wang, R | 1 |
Liu, S | 1 |
He, H | 1 |
Dong, X | 2 |
Yang, M | 2 |
Yang, Q | 1 |
Duan, S | 1 |
Yu, Y | 2 |
Han, J | 3 |
Zhang, C | 3 |
Chen, L | 2 |
Yang, X | 1 |
Li, W | 3 |
Wang, T | 2 |
Campbell, DA | 1 |
Gao, K | 1 |
Zager, RA | 1 |
Johnson, ACM | 1 |
Guillem, A | 1 |
Keyser, J | 1 |
Singh, B | 1 |
Steubl, D | 1 |
Schneider, MP | 1 |
Meiselbach, H | 1 |
Nadal, J | 1 |
Schmid, MC | 1 |
Saritas, T | 1 |
Krane, V | 1 |
Sommerer, C | 1 |
Baid-Agrawal, S | 1 |
Voelkl, J | 1 |
Kotsis, F | 1 |
Köttgen, A | 1 |
Eckardt, KU | 2 |
Scherberich, JE | 1 |
Li, H | 5 |
Yao, L | 2 |
Sun, L | 3 |
Zhu, Z | 1 |
Naren, N | 1 |
Zhang, XX | 2 |
Gentile, GL | 1 |
Rupert, AS | 1 |
Carrasco, LI | 1 |
Garcia, EM | 1 |
Kumar, NG | 1 |
Walsh, SW | 1 |
Jefferson, KK | 1 |
Guest, RL | 1 |
Samé Guerra, D | 1 |
Wissler, M | 1 |
Grimm, J | 1 |
Silhavy, TJ | 1 |
Lee, JH | 2 |
Yoo, JS | 1 |
Kim, Y | 1 |
Kim, JS | 2 |
Lee, EJ | 1 |
Roe, JH | 1 |
Delorme, M | 1 |
Bouchard, PA | 1 |
Simon, M | 1 |
Simard, S | 1 |
Lellouche, F | 1 |
D'Urzo, KA | 1 |
Mok, F | 1 |
D'Urzo, AD | 1 |
Koneru, B | 1 |
Lopez, G | 1 |
Farooqi, A | 1 |
Conkrite, KL | 1 |
Nguyen, TH | 1 |
Macha, SJ | 1 |
Modi, A | 1 |
Rokita, JL | 1 |
Urias, E | 1 |
Hindle, A | 1 |
Davidson, H | 1 |
Mccoy, K | 1 |
Nance, J | 1 |
Yazdani, V | 1 |
Irwin, MS | 1 |
Yang, S | 1 |
Wheeler, DA | 1 |
Maris, JM | 1 |
Diskin, SJ | 1 |
Reynolds, CP | 1 |
Abhilash, L | 1 |
Kalliyil, A | 1 |
Sheeba, V | 1 |
Hartley, AM | 2 |
Meunier, B | 2 |
Pinotsis, N | 1 |
Maréchal, A | 2 |
Xu, JY | 1 |
Genko, N | 1 |
Haraux, F | 1 |
Rich, PR | 1 |
Kamalanathan, M | 1 |
Doyle, SM | 1 |
Xu, C | 1 |
Achberger, AM | 1 |
Wade, TL | 1 |
Schwehr, K | 1 |
Santschi, PH | 1 |
Sylvan, JB | 1 |
Quigg, A | 1 |
Leong, W | 1 |
Xu, W | 2 |
Gao, S | 1 |
Zhai, X | 1 |
Wang, C | 2 |
Gilson, E | 1 |
Ye, J | 1 |
Lu, Y | 1 |
Yan, R | 1 |
Zhang, Y | 6 |
Hu, Z | 1 |
You, Q | 1 |
Cai, Q | 1 |
Yang, D | 1 |
Gu, S | 1 |
Dai, H | 1 |
Zhao, X | 1 |
Gui, C | 1 |
Gui, J | 1 |
Wu, PK | 1 |
Hong, SK | 1 |
Starenki, D | 1 |
Oshima, K | 1 |
Shao, H | 1 |
Gestwicki, JE | 1 |
Tsai, S | 1 |
Park, JI | 1 |
Wang, Y | 7 |
Zhao, R | 1 |
Gu, Z | 1 |
Dong, C | 2 |
Guo, G | 1 |
Li, L | 4 |
Barrett, HE | 1 |
Meester, EJ | 1 |
van Gaalen, K | 1 |
van der Heiden, K | 1 |
Krenning, BJ | 1 |
Beekman, FJ | 1 |
de Blois, E | 1 |
de Swart, J | 1 |
Verhagen, HJ | 1 |
Maina, T | 1 |
Nock, BA | 1 |
Norenberg, JP | 1 |
de Jong, M | 1 |
Gijsen, FJH | 1 |
Bernsen, MR | 1 |
Martínez-Milla, J | 1 |
Galán-Arriola, C | 1 |
Carnero, M | 1 |
Cobiella, J | 1 |
Pérez-Camargo, D | 1 |
Bautista-Hernández, V | 1 |
Rigol, M | 1 |
Solanes, N | 1 |
Villena-Gutierrez, R | 1 |
Lobo, M | 1 |
Mateo, J | 1 |
Vilchez-Tschischke, JP | 1 |
Salinas, B | 1 |
Cussó, L | 1 |
López, GJ | 1 |
Fuster, V | 1 |
Desco, M | 1 |
Sanchez-González, J | 1 |
Ibanez, B | 1 |
van den Berg, P | 1 |
Schweitzer, DH | 1 |
van Haard, PMM | 1 |
Geusens, PP | 1 |
van den Bergh, JP | 1 |
Zhu, X | 1 |
Huang, X | 2 |
Xu, H | 2 |
Yang, G | 2 |
Lin, Z | 1 |
Salem, HF | 1 |
Nafady, MM | 1 |
Kharshoum, RM | 1 |
Abd El-Ghafar, OA | 1 |
Farouk, HO | 1 |
Domiciano, D | 1 |
Nery, FC | 1 |
de Carvalho, PA | 1 |
Prudente, DO | 1 |
de Souza, LB | 1 |
Chalfun-Júnior, A | 1 |
Paiva, R | 1 |
Marchiori, PER | 1 |
Lu, M | 2 |
An, Z | 1 |
Jiang, J | 2 |
Li, J | 7 |
Du, S | 1 |
Zhou, H | 1 |
Cui, J | 1 |
Wu, W | 1 |
Liu, Y | 8 |
Song, J | 1 |
Lian, Q | 1 |
Uddin Ahmad, Z | 1 |
Gang, DD | 1 |
Konggidinata, MI | 1 |
Gallo, AA | 1 |
Zappi, ME | 1 |
Yang, TWW | 1 |
Johari, Y | 1 |
Burton, PR | 1 |
Earnest, A | 1 |
Shaw, K | 1 |
Hare, JL | 1 |
Brown, WA | 1 |
Kim, GA | 1 |
Han, S | 1 |
Choi, GH | 1 |
Choi, J | 1 |
Lim, YS | 1 |
Gallo, A | 1 |
Cancelli, C | 1 |
Ceron, E | 1 |
Covino, M | 1 |
Capoluongo, E | 1 |
Pocino, K | 1 |
Ianiro, G | 1 |
Cammarota, G | 1 |
Gasbarrini, A | 1 |
Montalto, M | 1 |
Somasundar, Y | 1 |
Lu, IC | 1 |
Mills, MR | 1 |
Qian, LY | 1 |
Olivares, X | 1 |
Ryabov, AD | 1 |
Collins, TJ | 1 |
Zhao, L | 1 |
Doddipatla, S | 1 |
Thomas, AM | 1 |
Nikolayev, AA | 1 |
Galimova, GR | 1 |
Azyazov, VN | 1 |
Mebel, AM | 1 |
Kaiser, RI | 1 |
Guo, S | 1 |
Yang, P | 1 |
Yu, X | 2 |
Zhang, H | 1 |
Yu, B | 2 |
Han, B | 1 |
George, MW | 1 |
Moor, MB | 1 |
Bonny, O | 1 |
Langenberg, E | 1 |
Paik, H | 1 |
Smith, EH | 1 |
Nair, HP | 1 |
Hanke, I | 1 |
Ganschow, S | 1 |
Catalan, G | 1 |
Domingo, N | 1 |
Schlom, DG | 1 |
Assefa, MK | 1 |
Wu, G | 2 |
Hayton, TW | 1 |
Becker, B | 1 |
Enikeev, D | 1 |
Netsch, C | 1 |
Gross, AJ | 1 |
Laukhtina, E | 1 |
Glybochko, P | 1 |
Rapoport, L | 1 |
Herrmann, TRW | 1 |
Taratkin, M | 1 |
Dai, W | 1 |
Shi, J | 2 |
Carreno, J | 1 |
Kloner, RA | 1 |
Pickersgill, NA | 1 |
Vetter, JM | 1 |
Kim, EH | 1 |
Cope, SJ | 1 |
Du, K | 1 |
Venkatesh, R | 1 |
Giardina, JD | 1 |
Saad, NES | 1 |
Bhayani, SB | 1 |
Figenshau, RS | 1 |
Eriksson, J | 1 |
Landfeldt, E | 1 |
Ireland, S | 1 |
Jackson, C | 1 |
Wyatt, E | 1 |
Gaudig, M | 1 |
Stancill, JS | 1 |
Happ, JT | 1 |
Broniowska, KA | 1 |
Hogg, N | 1 |
Corbett, JA | 1 |
Tang, LF | 1 |
Bi, YL | 1 |
Fan, Y | 2 |
Sun, YB | 1 |
Wang, AL | 1 |
Xiao, BH | 1 |
Wang, LF | 1 |
Qiu, SW | 1 |
Guo, SW | 1 |
Wáng, YXJ | 1 |
Sun, J | 2 |
Chu, S | 1 |
Pan, Q | 1 |
Li, D | 2 |
Zheng, S | 2 |
Ma, L | 1 |
Wang, L | 4 |
Hu, T | 1 |
Wang, F | 1 |
Han, Z | 1 |
Yin, Z | 1 |
Ge, X | 1 |
Xie, K | 1 |
Lei, P | 1 |
Dias-Santagata, D | 1 |
Lennerz, JK | 1 |
Sadow, PM | 1 |
Frazier, RP | 1 |
Govinda Raju, S | 1 |
Henry, D | 1 |
Chung, T | 1 |
Kherani, J | 1 |
Rothenberg, SM | 1 |
Wirth, LJ | 1 |
Marti, CN | 1 |
Choi, NG | 1 |
Bae, SJ | 1 |
Ni, L | 1 |
Luo, X | 1 |
Dai, T | 1 |
Yang, Y | 3 |
Lee, R | 1 |
Fleischer, AS | 1 |
Wemhoff, AP | 1 |
Ford, CR | 1 |
Kleppinger, EL | 1 |
Helms, K | 1 |
Bush, AA | 1 |
Luna-Abanto, J | 1 |
García Ruiz, L | 1 |
Laura Martinez, J | 1 |
Álvarez Larraondo, M | 1 |
Villoslada Terrones, V | 1 |
Dukic, L | 1 |
Maric, N | 1 |
Simundic, AM | 1 |
Chogtu, B | 1 |
Ommurugan, B | 1 |
Thomson, SR | 1 |
Kalthur, SG | 1 |
Benidir, M | 1 |
El Massoudi, S | 1 |
El Ghadraoui, L | 1 |
Lazraq, A | 1 |
Benjelloun, M | 1 |
Errachidi, F | 1 |
Cassar, M | 1 |
Law, AD | 1 |
Chow, ES | 1 |
Giebultowicz, JM | 1 |
Kretzschmar, D | 1 |
Salonurmi, T | 1 |
Nabil, H | 1 |
Ronkainen, J | 1 |
Hyötyläinen, T | 1 |
Hautajärvi, H | 1 |
Savolainen, MJ | 1 |
Tolonen, A | 1 |
Orešič, M | 1 |
Känsäkoski, P | 1 |
Rysä, J | 1 |
Hakkola, J | 1 |
Hukkanen, J | 1 |
Zhu, N | 1 |
Li, Y | 4 |
Du, Q | 1 |
Hao, P | 1 |
Cao, X | 1 |
Li, CX | 1 |
Zhao, S | 1 |
Luo, XM | 1 |
Feng, JX | 1 |
Gonzalez-Cotto, M | 1 |
Guo, L | 1 |
Karwan, M | 1 |
Sen, SK | 1 |
Barb, J | 1 |
Collado, CJ | 1 |
Elloumi, F | 1 |
Palmieri, EM | 1 |
Boelte, K | 1 |
Kolodgie, FD | 1 |
Finn, AV | 1 |
Biesecker, LG | 1 |
McVicar, DW | 1 |
Qu, F | 1 |
Deng, Z | 1 |
Xie, Y | 2 |
Tang, J | 3 |
Chen, Z | 3 |
Luo, W | 1 |
Xiong, D | 1 |
Zhao, D | 1 |
Fang, J | 1 |
Zhou, Z | 1 |
Niu, PP | 1 |
Song, B | 1 |
Xu, YM | 1 |
Zhang, Z | 3 |
Qiu, N | 1 |
Yin, J | 1 |
Zhang, J | 3 |
Guo, W | 1 |
Liu, M | 2 |
Liu, T | 2 |
Chen, D | 5 |
Luo, K | 1 |
He, Z | 2 |
Zheng, G | 1 |
Xu, F | 1 |
Sun, W | 1 |
Yin, F | 1 |
van Hest, JCM | 1 |
Du, L | 3 |
Shi, X | 1 |
Kang, S | 1 |
Duan, W | 1 |
Zhang, S | 2 |
Feng, J | 2 |
Qi, N | 1 |
Shen, G | 1 |
Ren, H | 1 |
Shang, Q | 1 |
Zhao, W | 2 |
Yang, Z | 2 |
Jiang, X | 2 |
Alame, M | 1 |
Cornillot, E | 1 |
Cacheux, V | 1 |
Tosato, G | 1 |
Four, M | 1 |
De Oliveira, L | 1 |
Gofflot, S | 1 |
Delvenne, P | 1 |
Turtoi, E | 1 |
Cabello-Aguilar, S | 1 |
Nishiyama, M | 1 |
Turtoi, A | 1 |
Costes-Martineau, V | 1 |
Colinge, J | 1 |
Guo, Q | 1 |
Quan, M | 1 |
Dong, J | 1 |
Bai, J | 1 |
Han, R | 1 |
Cai, Y | 1 |
Lv, YQ | 1 |
Chen, Q | 1 |
Lyu, HD | 1 |
Deng, L | 1 |
Zhou, D | 1 |
Xiao, X | 1 |
De Langhe, S | 1 |
Billadeau, DD | 1 |
Lou, Z | 1 |
Zhang, JS | 1 |
Xue, Z | 1 |
Shen, XD | 1 |
Gao, F | 1 |
Busuttil, RW | 1 |
Kupiec-Weglinski, JW | 1 |
Ji, H | 1 |
Otano, I | 1 |
Alvarez, M | 1 |
Minute, L | 1 |
Ochoa, MC | 1 |
Migueliz, I | 1 |
Molina, C | 1 |
Azpilikueta, A | 1 |
de Andrea, CE | 1 |
Etxeberria, I | 1 |
Sanmamed, MF | 1 |
Teijeira, Á | 1 |
Berraondo, P | 1 |
Melero, I | 1 |
Zhong, Z | 1 |
Xie, X | 1 |
Yu, Q | 1 |
Zhou, C | 1 |
Liu, C | 2 |
Liu, W | 1 |
Chen, W | 2 |
Yin, Y | 1 |
Li, CW | 1 |
Hsu, JL | 1 |
Zhou, Q | 1 |
Hu, B | 1 |
Fu, P | 1 |
Atyah, M | 1 |
Ma, Q | 2 |
Dong, Q | 1 |
Hung, MC | 1 |
Ren, N | 1 |
Huang, P | 1 |
Liao, R | 1 |
Chen, X | 3 |
Cao, Q | 1 |
Yuan, X | 1 |
Nie, W | 1 |
Yang, J | 2 |
Shao, B | 1 |
Ma, X | 1 |
Bi, Z | 1 |
Liang, X | 1 |
Tie, Y | 1 |
Mo, F | 1 |
Xie, D | 1 |
Wei, Y | 1 |
Wei, X | 2 |
Dokla, EME | 1 |
Fang, CS | 1 |
Chu, PC | 1 |
Chang, CS | 1 |
Abouzid, KAM | 1 |
Chen, CS | 1 |
Blaszczyk, R | 1 |
Brzezinska, J | 1 |
Dymek, B | 1 |
Stanczak, PS | 1 |
Mazurkiewicz, M | 1 |
Olczak, J | 1 |
Nowicka, J | 1 |
Dzwonek, K | 1 |
Zagozdzon, A | 1 |
Golab, J | 1 |
Golebiowski, A | 1 |
Xin, Z | 1 |
Himmelbauer, MK | 1 |
Jones, JH | 1 |
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Sullivan, JM | 1 |
Kang, ES | 1 |
McIlwain, H | 1 |
Poll, JD | 1 |
Fox, IH | 1 |
Dóra, E | 1 |
Whitfield, CF | 1 |
Morgan, HE | 1 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
1 review available for adenine and Hypoxia
Trials
1 trial available for adenine and Hypoxia
Other Studies
46 other studies available for adenine and Hypoxia
Article | Year |
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Suppression of CHOP Reduces Neuronal Apoptosis and Rescues Cognitive Impairment Induced by Intermittent Hypoxia by Inhibiting Bax and Bak Activation.
Topics: Adenine; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; | 2021 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
The role of RNA m
Topics: Adenine; Animals; Animals, Newborn; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmona | 2021 |
Hypoxic preconditioning-induced autophagy enhances survival of engrafted endothelial progenitor cells in ischaemic limb.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Hypoxia; Cell Survival; Cells, Cultured; Endothelial Pr | 2017 |
Inhibition of autophagy by 3-MA promotes hypoxia-induced apoptosis in human colorectal cancer cells.
Topics: Adenine; Annexin A5; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasm | 2019 |
Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy.
Topics: Adenine; Animals; Autophagy; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cells, Cultured; Hypo | 2013 |
Intermittent-hypoxia induced autophagy attenuates contractile dysfunction and myocardial injury in rat heart.
Topics: Adenine; Animals; Autophagy; Chloroquine; Heart Diseases; Heart Failure; Hypoxia; Lysosomes; Male; M | 2013 |
Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance.
Topics: Adenine; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Br | 2013 |
The c10orf10 gene product is a new link between oxidative stress and autophagy.
Topics: Adenine; Animals; Autophagy; Biomarkers; Blotting, Western; Carcinoma, Hepatocellular; Chlorocebus a | 2014 |
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.
Topics: Adenine; Cell Line; Epithelium; Gene Expression Regulation; Humans; Hypoxia; Kidney Diseases; Kidney | 2015 |
Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase-Dependent Cell Death and Leads to Mild Growth Retardation.
Topics: Adenine; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Ca | 2015 |
Activation of volume-sensitive Cl- channel mediates autophagy-related cell death in myocardial ischaemia/reperfusion injury.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Proliferation; Chloride Channels; Cytokines; Hydrogen-I | 2016 |
Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2.
Topics: Adenine; Autophagy; Cell Line, Tumor; Cell Membrane; Chloroquine; Culture Media; Endothelium, Vascul | 2008 |
HPLC-UV measurements of metabolites in the supernatant of endothelial cells exposed to oxidative stress.
Topics: Adenine; Animals; Aorta; Biomarkers; Cells, Cultured; Chromatography, High Pressure Liquid; Endothel | 2010 |
Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury.
Topics: Adenine; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; | 2010 |
AKT loss in human epithelial cells treated with severe hypoxia.
Topics: Adenine; Autophagy; Calpain; Chromones; Enzyme Inhibitors; Epithelial Cells; HeLa Cells; Humans; Hyp | 2010 |
ADENINE NUCLEOTIDE DEGRADATION IN THE RABBIT HEART.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Aminohydrolases; Animals; Azaguanine; Dicumaro | 1964 |
Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Cattle; Endothelium, Vascular | 2006 |
Acute hypoxia induces vasodilation and increases coronary blood flow by activating inward rectifier K(+) channels.
Topics: Acute Disease; Adenine; Animals; Blood Pressure; Carbazoles; Coronary Circulation; Cyclic AMP-Depend | 2007 |
Cardiac synthesis and degradation of pyridine nucleotides and the level of energy-rich phosphates influenced by various precursors.
Topics: Adenine; Adenosine Triphosphate; Animals; Glycoside Hydrolases; Guinea Pigs; Hypoxia; Myocardial Con | 1983 |
Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; C | 1984 |
Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Electrophysiology; Hippocampu | 1994 |
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hy | 1993 |
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproter | 1996 |
AMP degradation in the perfused rat heart during 2-deoxy-D-glucose perfusion and anoxia. Part II: The determination of the degradation pathways using an adenosine deaminase inhibitor.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Anti | 1996 |
Extracellular acidosis delays cell death against glucose-oxygen deprivation in neuroblastoma x glioma hybrid cells.
Topics: Acidosis; Adenine; Cell Death; Cell Survival; Flow Cytometry; Glioma; Glucose; Hydrogen-Ion Concentr | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyri | 1997 |
Ischemic preconditioning prevents the impairment of hypoxic coronary vasodilatation caused by ischemia/reperfusion: role of adenosine A1/A3 and bradykinin B2 receptor activation.
Topics: Adenine; Adenosine; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Guinea P | 1997 |
Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement.
Topics: Adenine; Adenosine Triphosphate; Adenylate Kinase; Animals; Blotting, Northern; Catalysis; Cloning, | 2000 |
Allopurinol enhances adenine nucleotide levels and improves myocardial function in isolated hypoxic rat heart.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animal | 2001 |
Release of 3H-purines from [3H]-adenine labelled rabbit kidney following sympathetic nerve stimulation, and its inhibition by alpha-adrenoceptor blockage.
Topics: Adenine; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Electric Stimulation; Female; Hypoxi | 1978 |
Release of 3H-nucleosides from 3H-adenine labelled hypothalamic synaptosomes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Antimycin A; Chromatography, Gel; Chromatograph | 1979 |
The postanoxic regeneration of 5'-adenosine nucleotides in rabbit kidney tissue during in vitro perfusion.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine T | 1976 |
Measurement of rat plasma adenosine levels during normoxia and hypoxia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Blood Pressure; Carbon Dioxide; Chromatography | 1992 |
Evaluation of N-0861, (+-)-N6-endonorbornan-2-yl-9-methyladenine, as an A1 subtype-selective adenosine receptor antagonist in the guinea pig isolated heart.
Topics: Adenine; Adenosine; Animals; Carrier Proteins; Coronary Vessels; Guinea Pigs; Heart; Heart Conductio | 1992 |
[The oxygen system of an isolated heart during its perfusion with a suspension of human erythrocytes after different periods of their preservation in a solution containing adenine].
Topics: Adenine; Animals; Anticoagulants; Blood Preservation; Citrates; Cryopreservation; Cryoprotective Age | 1991 |
5-Amino-4-imidazolecarboxamide riboside raises adenosine in perfused hypoxic rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Cardiac Out | 1991 |
Plasma xanthine oxidase and resistance to hypoxia: effect of purines and alcohol administration.
Topics: Adenine; Allopurinol; Animals; Cricetinae; Ethanol; Female; Guinea Pigs; Hypoxanthines; Hypoxia; Ino | 1991 |
Effect of propionyl carnitine on energy charge and adenine nucleotide content of cardiac endothelial cells during hypoxia.
Topics: Adenine; Animals; Carnitine; Cells, Cultured; Endothelium, Vascular; Energy Metabolism; Hypoxia; Oxi | 1991 |
Species-dependent effects of adenosine on heart rate and atrioventricular nodal conduction. Mechanism and physiological implications.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Atrioventricular Node; Bundle of His; D | 1990 |
Influence of hypoxanthine, allopurinol and adenine on resistance of rats and hamsters to hypobaric hypoxia.
Topics: Adenine; Allopurinol; Animals; Cricetinae; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Rats; Rats, | 1990 |
Dose effects of adenine on myocardial ATP content in the post-anoxic nonworking rat heart.
Topics: Adenine; Adenosine Triphosphate; Animals; Heart; Hypoxia; In Vitro Techniques; Male; Myocardium; Rat | 1989 |
Adenosine in cerebral homeostatic role: appraisal through actions of homocysteine, colchicine, and dipyridamole.
Topics: Adenine; Adenosine; Animals; Cerebral Cortex; Colchicine; Dipyridamole; Glutamates; Guinea Pigs; Hom | 1986 |
Adenosine triphosphate degradation in specific disease.
Topics: Adenine; Adenosine Triphosphate; Biotransformation; Carnitine O-Palmitoyltransferase; Ethanol; Fruct | 1985 |
Adenosine and hypoxic vasodilatation.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cerebrovascular Circulation; Coformycin; Dogs; Hyp | 1985 |
Effect of anoxia on sugar transport in avian erythrocytes.
Topics: Adenine; Adenosine; Aerobiosis; Anaerobiosis; Animals; Biological Transport; Blood Glucose; Buffers; | 1973 |