Page last updated: 2024-10-16

adenine and Hepatitis C, Chronic

adenine has been researched along with Hepatitis C, Chronic in 33 studies

Hepatitis C, Chronic: INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
" Treatment of chronic hepatitis C in patients coinfected with HIV is a complex problem associated with toxicities and drug interactions between HIV antiretrovirals and interferon and ribavirin."7.79Short communication: Interferon/ribavirin treatment for HCV is associated with the development of hypophosphatemia in HIV/hepatitis C virus-coinfected patients. ( Funk, EK; Heytens, L; Kohli, A; Kottilil, S; Kwan, R; Masur, H; Nelson, A; Polis, MA; Shaffer, A; Shivakumar, B; Sneller, M, 2013)
"Psoriasis is a chronic, inflammatory disease affecting 2-3% of the worldwide population, and it may worsen with HIV or be detected as HIV cutaneous manifestation."6.48Complete resolution of erythrodermic psoriasis in an HIV and HCV patient unresponsive to antipsoriatic treatments after highly active antiretroviral therapy (Ritonavir, Atazanavir, Emtricitabine, Tenofovir). ( Cannizzaro, MV; Chimenti, S; Chiricozzi, A; Giunta, A; Nisticò, SP; Saraceno, R, 2012)
" The treatment of choice in chronic hepatitis C currently is pegylated interferon plus ribavirin."4.83Chronic Hepatitis B and C--current treatment and future therapeutic prospects. ( Müller, C, 2006)
" Chronic hepatitis C can be treated preferably with a combination therapy (pegylated interferons + Ribavirin)."4.82[Hepatitis: associated diseases. Risk groups -- prevention -- treatment]. ( Maier, KP, 2003)
" The conference issued recommendations on the investigation and management of chronic hepatitis B, including the use of lamivudine, adefovir and interferon."4.82The management of chronic viral hepatitis: a Canadian consensus conference 2004. ( Bain, V; Cooper, C; Lowe, C; Martin, S; Myers, RP; Sherman, M; Villeneuve, JP, 2004)
" Treatment of chronic hepatitis C in patients coinfected with HIV is a complex problem associated with toxicities and drug interactions between HIV antiretrovirals and interferon and ribavirin."3.79Short communication: Interferon/ribavirin treatment for HCV is associated with the development of hypophosphatemia in HIV/hepatitis C virus-coinfected patients. ( Funk, EK; Heytens, L; Kohli, A; Kottilil, S; Kwan, R; Masur, H; Nelson, A; Polis, MA; Shaffer, A; Shivakumar, B; Sneller, M, 2013)
"In children, the natural history of chronic hepatitis B and C is different from that in adults."2.49[Treatment of viral hepatitis in children]. ( Kekez, AJ, 2013)
"Those at risk for liver disease progression are usually treated with a combination of interferon (IFN) and ribavirin (RBV), which is not highly effective; it has low rates of sustained virologic response (SVR), especially for coinfected patients with HCV genotype 1 and those of African descent."2.48Management of patients coinfected with HCV and HIV: a close look at the role for direct-acting antivirals. ( Naggie, S; Sulkowski, MS, 2012)
"Psoriasis is a chronic, inflammatory disease affecting 2-3% of the worldwide population, and it may worsen with HIV or be detected as HIV cutaneous manifestation."2.48Complete resolution of erythrodermic psoriasis in an HIV and HCV patient unresponsive to antipsoriatic treatments after highly active antiretroviral therapy (Ritonavir, Atazanavir, Emtricitabine, Tenofovir). ( Cannizzaro, MV; Chimenti, S; Chiricozzi, A; Giunta, A; Nisticò, SP; Saraceno, R, 2012)
"Hepatitis B is a major public health problem in the world today."2.43Hepatitis B: the pathway to recovery through treatment. ( Hollinger, FB; Lau, DT, 2006)
" IFN therapy requires dosage reduction and close monitoring in patients with a GFR <50 ml/min/1."1.37Does the antiviral therapy of patients with chronic hepatitis exert nephrotoxic effects? ( Bob, F; Bozdog, G; Cioca, D; Curescu, M; Gadalean, F; Gluhovschi, C; Gluhovschi, G; Kaycsa, A; Petrica, L; Sporea, I; Velciov, S; Vernic, C, 2011)
"A total of 44 chronic hepatitis B (CHB) patients (mean age: 42 +/- 13."1.36[Genotype distribution of chronic hepatitis B and hepatitis C patients and investigation of the resistance patterns in hepatitis B cases]. ( Akcan, Y; Altindiş, M; Demirdal, T; Demirtürk, N; Gülamber, G; Kalayci, R, 2010)
"In this study, we present a case of renal failure in a patient who was on a tenofovir-containing regimen, resulting in extremely high tenofovir exposure and prolonged tenofovir monotherapy."1.35Prolonged exposure to tenofovir monotherapy 1 month after treatment discontinuation because of tenofovir-related renal failure. ( Beijnen, JH; Huitema, AD; Jansen, RS; Mulder, JW; Smits, PH; Ter Heine, R; van Gorp, EC; Wagenaar, JF, 2009)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's16 (48.48)29.6817
2010's16 (48.48)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Surial, B1
Cavassini, M1
Calmy, A1
Fehr, J1
Stöckle, M1
Bernasconi, E1
Roth, B1
Fux, CA1
Kovari, H1
Furrer, H1
Rauch, A1
Wandeler, G1
Leungsuwan, S1
Hooi, B1
Myint, KS1
Brooks, KM1
Castillo-Mancilla, JR1
Blum, J1
Huntley, R1
MaWhinney, S1
Alexander, K1
Kerr, BJ1
Ellison, L1
Bushman, LR1
MacBrayne, CE1
Anderson, PL1
Kiser, JJ1
Funk, EK1
Shaffer, A1
Shivakumar, B1
Sneller, M1
Polis, MA1
Masur, H1
Heytens, L1
Nelson, A1
Kwan, R1
Kottilil, S1
Kohli, A1
González-Artacho, C1
Rodríguez Sicilia, MJ1
Alegría-Motte, C1
Gómez García, M1
Sagnelli, E1
Pisaturo, M1
Martini, S1
Sagnelli, C1
Filippini, P1
Coppola, N1
Chokshi, S1
Cooksley, H1
Riva, A1
Phillips, S1
Williams, R1
Gaggar, A1
Naoumov, NV1
Kekez, AJ1
Hiramine, S1
Sugiyama, M1
Furusyo, N1
Uto, H1
Ido, A1
Tsubouchi, H1
Watanabe, H1
Ueno, Y1
Korenaga, M1
Murata, K1
Masaki, N1
Hayashi, J1
Thomas, DL1
Mizokami, M1
Zhao, PW1
Ma, L1
Ji, HF1
Yu, L1
Feng, JY1
Wang, J1
Liu, MY1
Jiang, YF1
Thong, VD1
Wasitthankasem, R1
Tangkijvanich, P1
Vongpunsawad, S1
Poovorawan, Y1
Mira, JA1
López-Cortés, LF1
Barreiro, P2
Tural, C1
Torres-Tortosa, M1
de Los Santos Gil, I1
Martín-Rico, P1
Ríos-Villegas, MJ1
Hernández-Burruezo, JJ1
Merino, D1
López-Ruz, MA1
Rivero, A1
Muñoz, L1
González-Serrano, M1
Collado, A1
Macías, J1
Viciana, P1
Soriano, V2
Pineda, JA1
Tillmann, H1
Patel, K1
McHutchison, J1
Tuma, P1
Vispo, E1
Valencia, ME1
Moreno, V1
Schildgen, O1
Ter Heine, R1
Huitema, AD1
Jansen, RS1
Smits, PH1
van Gorp, EC1
Wagenaar, JF1
Beijnen, JH1
Mulder, JW1
Wörmann, T1
Prüfer-Krämer, L1
Krämer, A1
Ortu, F1
Weimer, LE1
Floridia, M1
Manconi, PE1
Kalayci, R1
Altindiş, M1
Gülamber, G1
Demirtürk, N1
Akcan, Y1
Demirdal, T1
Gluhovschi, C1
Gadalean, F1
Kaycsa, A1
Curescu, M1
Sporea, I1
Gluhovschi, G1
Petrica, L1
Velciov, S1
Bozdog, G1
Bob, F1
Vernic, C1
Cioca, D1
Naggie, S1
Sulkowski, MS2
Chiricozzi, A1
Saraceno, R1
Cannizzaro, MV1
Nisticò, SP1
Chimenti, S1
Giunta, A1
Iino, S1
Maier, KP2
Sterling, RK1
Zhuang, H1
Zhou, YH1
Ferenci, P1
Sherman, M1
Bain, V1
Villeneuve, JP1
Myers, RP1
Cooper, C1
Martin, S1
Lowe, C1
Hollinger, FB1
Lau, DT1
Müller, C1
Dalmi, L1
Gervain, J1
Horváth, G1
Hunyady, B1
Ibrányi, E1
Makara, M1
Pár, A1
Szalay, F1
Tornai, I1
Telegdy, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-Label, Randomized Study to Determine the Impact of Antiretroviral Treatment in HCV/HIV-Coinfected Subjects With High CD4+ Cell Count on the Efficacy of Hepatitis C Treatment With Pegylated Interferon Alfa-2A and Ribavirin[NCT00100581]2 participants (Actual)InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for adenine and Hepatitis C, Chronic

ArticleYear
Advances in the treatment of hepatitis B virus/hepatitis C virus coinfection.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:10

    Topics: Adenine; Antiviral Agents; Coinfection; DNA, Viral; Drug Therapy, Combination; Guanine; Hepacivirus;

2014
[Treatment of viral hepatitis in children].
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2013, Volume: 67, Issue:4

    Topics: Adenine; Adolescent; Antiviral Agents; Child; Child Welfare; Drug Therapy, Combination; Female; Hepa

2013
[Role of tenofovir in HIV and hepatitis C virus coinfection].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Chemical and Drug

2008
Management of patients coinfected with HCV and HIV: a close look at the role for direct-acting antivirals.
    Gastroenterology, 2012, Volume: 142, Issue:6

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Coinfection; Deoxycytidine; Dideoxynucleosides; Disease

2012
Complete resolution of erythrodermic psoriasis in an HIV and HCV patient unresponsive to antipsoriatic treatments after highly active antiretroviral therapy (Ritonavir, Atazanavir, Emtricitabine, Tenofovir).
    Dermatology (Basel, Switzerland), 2012, Volume: 225, Issue:4

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Deoxycytidine;

2012
[Antiviral therapy for chronic viral hepatitis B and C].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2

    Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Interferon a

2003
[Hepatitis: associated diseases. Risk groups -- prevention -- treatment].
    Praxis, 2003, Aug-13, Volume: 92, Issue:33

    Topics: Adenine; Adult; Antiviral Agents; Child; DNA, Viral; Female; Hepacivirus; Hepatitis B; Hepatitis B S

2003
Hepatitis C virus in the setting of HIV or hepatitis B virus coinfection.
    Seminars in liver disease, 2004, Volume: 24 Suppl 2

    Topics: Adenine; Antiviral Agents; Comorbidity; Hepacivirus; Hepatitis B virus; Hepatitis C; Hepatitis C, Ch

2004
Treatment of chronic viral hepatitis.
    Best practice & research. Clinical gastroenterology, 2004, Volume: 18 Suppl

    Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Hepatitis B, Chronic; Hepatitis C, Chronic; He

2004
The management of chronic viral hepatitis: a Canadian consensus conference 2004.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2004, Volume: 18, Issue:12

    Topics: Adenine; Adult; Antiviral Agents; Canada; Child; Child, Preschool; Drug Therapy, Combination; Enzyme

2004
[Drug therapy in chronic liver disease].
    Praxis, 2005, Nov-30, Volume: 94, Issue:48

    Topics: Adenine; Administration, Oral; Anti-HIV Agents; Antiviral Agents; Azathioprine; Cholangitis, Scleros

2005
Hepatitis B: the pathway to recovery through treatment.
    Gastroenterology clinics of North America, 2006, Volume: 35, Issue:2

    Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis C, Chronic; Human

2006
Chronic Hepatitis B and C--current treatment and future therapeutic prospects.
    Wiener medizinische Wochenschrift (1946), 2006, Volume: 156, Issue:13-14

    Topics: Adenine; Antiviral Agents; DNA-Directed RNA Polymerases; Hepatitis B e Antigens; Hepatitis B, Chroni

2006

Trials

2 trials available for adenine and Hepatitis C, Chronic

ArticleYear
Identification of serum cytokine profiles associated with HBeAg seroconversion following antiviral treatment interruption.
    Viral immunology, 2014, Volume: 27, Issue:5

    Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; Cytokines; Female; Hepatitis B e Antigens; Hepatit

2014
Efficacy of pegylated interferon plus ribavirin treatment in HIV/hepatitis C virus co-infected patients receiving abacavir plus lamivudine or tenofovir plus either lamivudine or emtricitabine as nucleoside analogue backbone.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Blood; Cohort Studies; Deoxycytidine; Dideoxynucleosides; Emtricita

2008

Other Studies

18 other studies available for adenine and Hepatitis C, Chronic

ArticleYear
Rates and predictors of switching to tenofovir alafenamide-containing ART in a nationwide cohort.
    BMC infectious diseases, 2019, Oct-10, Volume: 19, Issue:1

    Topics: Adenine; Adult; Alanine; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Interactions; F

2019
Hypophosphatemic Osteomalacia Due to Adefovir-Induced Fanconi Syndrome.
    The American journal of medicine, 2020, Volume: 133, Issue:12

    Topics: Adenine; Aged; Alanine; Antiviral Agents; Fanconi Syndrome; Female; Hepatitis C, Chronic; Humans; Hy

2020
Increased tenofovir monoester concentrations in patients receiving tenofovir disoproxil fumarate with ledipasvir/sofosbuvir.
    The Journal of antimicrobial chemotherapy, 2019, 08-01, Volume: 74, Issue:8

    Topics: Adenine; Adolescent; Adult; Antiviral Agents; Benzimidazoles; Blood Chemical Analysis; Chromatograph

2019
Short communication: Interferon/ribavirin treatment for HCV is associated with the development of hypophosphatemia in HIV/hepatitis C virus-coinfected patients.
    AIDS research and human retroviruses, 2013, Volume: 29, Issue:9

    Topics: Adenine; Adult; Anti-HIV Agents; Antiviral Agents; Coinfection; Drug Interactions; Drug Therapy, Com

2013
[Outcome of chronic hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive drugs and anti-TNF agents].
    Gastroenterologia y hepatologia, 2014, Volume: 37, Issue:1

    Topics: Adalimumab; Adenine; Adult; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azathioprine; Crohn

2014
A thymine-adenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus.
    Journal of gastroenterology, 2015, Volume: 50, Issue:10

    Topics: Adenine; Adolescent; Adult; Aged; Alleles; Dinucleotide Repeats; DNA, Viral; Female; Gene Frequency;

2015
The expression of TLR-9, CD86, and CD95 phenotypes in circulating B cells of patients with chronic viral hepatitis B or C before and after antiviral therapy.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Adenine; Adult; Aged; Antibodies, Monoclonal; Antiviral Agents; B-Lymphocytes; B7-2 Antigen; DNA, Vi

2015
Prevalence of Thymine--Adenine Dinucleotide Repeat, IL28B and IFNL4 in Thai Population and Correlation with Spontaneous Clearance and Treatment Outcome of Hepatitis C Infection.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adenine; Adult; Alleles; Antiviral Agents; Asian People; Case-Control Studies; Dinucleotide Repeats;

2015
Hepatitis B virus viral load and treatment decision.
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:2

    Topics: Adenine; Algorithms; Antiviral Agents; Decision Making; DNA, Viral; Drug Resistance, Viral; Female;

2009
[Atazanavir-induced nephrolithiasis].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:2

    Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cy

2009
Peginterferon alfa-2a and ribavirin in Latino and non-Latino whites with hepatitis C.
    The New England journal of medicine, 2009, Apr-30, Volume: 360, Issue:18

    Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepa

2009
Prolonged exposure to tenofovir monotherapy 1 month after treatment discontinuation because of tenofovir-related renal failure.
    Antiviral therapy, 2009, Volume: 14, Issue:2

    Topics: Adenine; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis C, Chronic; HIV Infections; HI

2009
[Serological and sociodemographic differences in HBV-patients with and without migration background].
    Zeitschrift fur Gastroenterologie, 2010, Volume: 48, Issue:5

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Comorbidity; Cross-Sectional Studies; Edu

2010
Raltegravir, tenofovir, and emtricitabine in an HIV-infected patient with HCV chronic hepatitis, NNRTI intolerance and protease inhibitors-induced severe liver toxicity.
    European journal of medical research, 2010, Feb-26, Volume: 15, Issue:2

    Topics: Adenine; Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; Chemical and Drug Induced Liver Injury

2010
[Genotype distribution of chronic hepatitis B and hepatitis C patients and investigation of the resistance patterns in hepatitis B cases].
    Mikrobiyoloji bulteni, 2010, Volume: 44, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; DNA Mutational Analysis; DNA-Directed DNA Polyme

2010
Does the antiviral therapy of patients with chronic hepatitis exert nephrotoxic effects?
    Immunopharmacology and immunotoxicology, 2011, Volume: 33, Issue:4

    Topics: Adenine; Adult; Albuminuria; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis B, Chron

2011
[Active prevention and treatment of superinfection with HBV, HCV and HIV].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2004, Volume: 38, Issue:5

    Topics: Adenine; Antiretroviral Therapy, Highly Active; Hepatitis B, Chronic; Hepatitis C, Chronic; HIV Infe

2004
[Protocol for the treatment of chronic viral hepatitis].
    Orvosi hetilap, 2008, Jan-20, Volume: 149, Issue:3

    Topics: Adenine; Algorithms; Antiviral Agents; Clinical Protocols; Hepacivirus; Hepatitis B virus; Hepatitis

2008