adenine has been researched along with Heart Disease, Ischemic in 25 studies
Excerpt | Relevance | Reference |
---|---|---|
"Mounting evidence suggests a protective effect of exogenous adenosine in myocardial ischemia and reperfusion." | 3.68 | Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects. ( Abd-Elfattah, AS; Bolli, R; Jeroudi, MO; Sekili, S; Sun, JZ; Tang, XL; Zughaib, ME, 1993) |
"Adenosine is suggested to be a potential candidate because of its high uptake and rapid intracellular sequestration." | 1.32 | Tracer adenosine: a novel myocardial flow marker. ( Deussen, A; Lauer, T; Loncar, R, 2003) |
"Treatment with BW A1433U reduced TOIC [8." | 1.29 | Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia. ( Lasley, RD; Mentzer, RM, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 15 (60.00) | 18.2507 |
2000's | 5 (20.00) | 29.6817 |
2010's | 4 (16.00) | 24.3611 |
2020's | 1 (4.00) | 2.80 |
Authors | Studies |
---|---|
Sugimoto, S | 1 |
Shingu, Y | 1 |
Doenst, T | 1 |
Yamakawa, T | 1 |
Asai, H | 1 |
Wakasa, S | 1 |
Matsui, Y | 1 |
Abd-Elfattah, AS | 7 |
Tuchy, GE | 1 |
Jessen, ME | 5 |
Salter, DR | 1 |
Goldstein, JP | 1 |
Brunsting, LA | 1 |
Wechsler, AS | 6 |
Lougiakis, N | 1 |
Papapetropoulos, A | 1 |
Gikas, E | 1 |
Toumpas, S | 1 |
Efentakis, P | 1 |
Wedmann, R | 1 |
Zoga, A | 1 |
Zhou, Z | 1 |
Iliodromitis, EK | 1 |
Skaltsounis, AL | 1 |
Filipovic, MR | 1 |
Pouli, N | 1 |
Marakos, P | 1 |
Andreadou, I | 1 |
Xia, Y | 2 |
Liu, Y | 1 |
Xia, T | 1 |
Li, X | 1 |
Huo, C | 1 |
Jia, X | 1 |
Wang, L | 2 |
Xu, R | 1 |
Wang, N | 1 |
Zhang, M | 1 |
Li, H | 1 |
Wang, X | 1 |
Ding, M | 1 |
Lauer, T | 1 |
Loncar, R | 1 |
Deussen, A | 1 |
Blunt, BC | 1 |
Chen, Y | 1 |
Potter, JD | 1 |
Hofmann, PA | 1 |
Willems, L | 1 |
Zatta, A | 1 |
Holmgren, K | 1 |
Ashton, KJ | 1 |
Headrick, JP | 1 |
Zarrinpashneh, E | 1 |
Carjaval, K | 1 |
Beauloye, C | 1 |
Ginion, A | 1 |
Mateo, P | 1 |
Pouleur, AC | 1 |
Horman, S | 1 |
Vaulont, S | 1 |
Hoerter, J | 1 |
Viollet, B | 1 |
Hue, L | 1 |
Vanoverschelde, JL | 1 |
Bertrand, L | 1 |
Gallagher, KP | 1 |
McClanahan, TB | 1 |
Martin, BJ | 1 |
Saganek, LJ | 1 |
Ignasiak, DP | 1 |
Mertz, TE | 1 |
Van Wylen, DG | 2 |
Vinten-Johansen, J | 1 |
Tan, ZT | 1 |
Wang, XW | 1 |
Zughaib, ME | 1 |
Jeroudi, MO | 1 |
Sun, JZ | 1 |
Sekili, S | 1 |
Tang, XL | 1 |
Bolli, R | 1 |
Sandhu, GS | 1 |
Burrier, AC | 1 |
Janero, DR | 1 |
Xu, J | 1 |
Tong, H | 1 |
Hurt, CM | 1 |
Pelleg, A | 1 |
Lasley, RD | 1 |
Mentzer, RM | 1 |
Khatchikian, G | 1 |
Zweier, JL | 1 |
Mallet, RT | 1 |
Lee, SC | 1 |
Downey, HF | 1 |
Manthei, SA | 1 |
Reiling, CM | 1 |
Maddox, RP | 1 |
Rebeyka, IM | 1 |
Lekven, J | 1 |
Hirai, K | 1 |
Ashraf, M | 1 |
Schreieck, J | 1 |
Richardt, G | 1 |
Demaison, L | 1 |
Moreau, D | 1 |
Vergely-Vandriesse, C | 1 |
Grégoire, S | 1 |
Degois, M | 1 |
Rochette, L | 1 |
1 review available for adenine and Heart Disease, Ischemic
Article | Year |
---|---|
Does adenosine deaminase inhibition protect ischemic myocardium?
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Humans; In Vitro Techniques; My | 1994 |
24 other studies available for adenine and Heart Disease, Ischemic
Article | Year |
---|---|
Autophagy during left ventricular redilation after ventriculoplasty: Insights from a rat model of ischemic cardiomyopathy.
Topics: Adenine; Animals; Autophagy; Autophagy-Related Proteins; Cardiomyopathy, Dilated; Cardiomyoplasty; C | 2022 |
Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: hot shot drug delivery befor
Topics: Adenine; Adenosine Triphosphate; Animals; Cold Ischemia; Disease Models, Animal; Dogs; Equilibrative | 2013 |
Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents.
Topics: Adenine; Animals; Blood Pressure; Cardiotonic Agents; Drug Design; Heart Rate; Hydrogen Sulfide; Mal | 2016 |
Activation of volume-sensitive Cl- channel mediates autophagy-related cell death in myocardial ischaemia/reperfusion injury.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Proliferation; Chloride Channels; Cytokines; Hydrogen-I | 2016 |
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Chromatography, High Pressure Liquid; Constriction | 2012 |
Tracer adenosine: a novel myocardial flow marker.
Topics: Adenine; Adenosine; Alprostadil; Animals; Carbon Radioisotopes; Coronary Circulation; Dogs; Isotope | 2003 |
Modest actomyosin energy conservation increases myocardial postischemic function.
Topics: Actomyosin; Adenine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Creatine; | 2005 |
Age-related changes in ischemic tolerance in male and female mouse hearts.
Topics: Adenine; Adenosine Diphosphate; Aging; Animals; Collagen; Coronary Vessels; Female; Heart; Hydro-Lya | 2005 |
Role of the alpha2-isoform of AMP-activated protein kinase in the metabolic response of the heart to no-flow ischemia.
Topics: Acetyl-CoA Carboxylase; Adenine; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Fat | 2006 |
Verapamil, ribose and adenine enhance resynthesis of postischemic myocardial ATP.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Calcium; Heart; Male; Myocardial Isch | 1994 |
Nucleoside trapping during reperfusion prevents ventricular dysfunction, "stunning," in absence of adenosine. Possible separation between ischemic and reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; B | 1994 |
Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dogs; Female; Heart; Inosi | 1994 |
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; M | 1993 |
Adenosine deaminase inhibitors attenuate ischemic injury and preserve energy balance in isolated guinea pig heart.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Coformycin; Creatine Kinase; Energy Metabolism; Gu | 1993 |
Endogenous adenosine, A1 adenosine receptor, and pertussis toxin sensitive guanine nucleotide binding protein mediate hypoxia induced AV nodal conduction block in guinea pig heart in vivo.
Topics: Adenine; Adenosine; Animals; Female; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Block; Male; My | 1993 |
Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia.
Topics: Adenine; Adenosine; Animals; Glucose; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardia | 1993 |
Adenosine deaminase inhibition prevents free radical-mediated injury in the postischemic heart.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Electro | 1996 |
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproter | 1996 |
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High | 1998 |
Role of nucleoside transport and purine release in a rabbit model of myocardial stunning.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Carrier Proteins; Dogs; Enzym | 1998 |
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: role of purine release in ischemic and reperfusion injury.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Carrier Proteins; | 1998 |
Modulation of adenosine effects in attenuation of ischemia and reperfusion injury in rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Heart; Heart Rate; I | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiogra | 1999 |
Effects of dietary polyunsaturated fatty acids and hepatic steatosis on the functioning of isolated working rat heart under normoxic conditions and during post-ischemic reperfusion.
Topics: Adenine; Animals; Aorta; Ascorbic Acid; Body Weight; Cardiac Output; Cell Respiration; Cholesterol, | 2001 |