Page last updated: 2024-10-16

adenine and Heart Disease, Ischemic

adenine has been researched along with Heart Disease, Ischemic in 25 studies

Research Excerpts

ExcerptRelevanceReference
"Mounting evidence suggests a protective effect of exogenous adenosine in myocardial ischemia and reperfusion."3.68Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects. ( Abd-Elfattah, AS; Bolli, R; Jeroudi, MO; Sekili, S; Sun, JZ; Tang, XL; Zughaib, ME, 1993)
"Adenosine is suggested to be a potential candidate because of its high uptake and rapid intracellular sequestration."1.32Tracer adenosine: a novel myocardial flow marker. ( Deussen, A; Lauer, T; Loncar, R, 2003)
"Treatment with BW A1433U reduced TOIC [8."1.29Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia. ( Lasley, RD; Mentzer, RM, 1993)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (60.00)18.2507
2000's5 (20.00)29.6817
2010's4 (16.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Sugimoto, S1
Shingu, Y1
Doenst, T1
Yamakawa, T1
Asai, H1
Wakasa, S1
Matsui, Y1
Abd-Elfattah, AS7
Tuchy, GE1
Jessen, ME5
Salter, DR1
Goldstein, JP1
Brunsting, LA1
Wechsler, AS6
Lougiakis, N1
Papapetropoulos, A1
Gikas, E1
Toumpas, S1
Efentakis, P1
Wedmann, R1
Zoga, A1
Zhou, Z1
Iliodromitis, EK1
Skaltsounis, AL1
Filipovic, MR1
Pouli, N1
Marakos, P1
Andreadou, I1
Xia, Y2
Liu, Y1
Xia, T1
Li, X1
Huo, C1
Jia, X1
Wang, L2
Xu, R1
Wang, N1
Zhang, M1
Li, H1
Wang, X1
Ding, M1
Lauer, T1
Loncar, R1
Deussen, A1
Blunt, BC1
Chen, Y1
Potter, JD1
Hofmann, PA1
Willems, L1
Zatta, A1
Holmgren, K1
Ashton, KJ1
Headrick, JP1
Zarrinpashneh, E1
Carjaval, K1
Beauloye, C1
Ginion, A1
Mateo, P1
Pouleur, AC1
Horman, S1
Vaulont, S1
Hoerter, J1
Viollet, B1
Hue, L1
Vanoverschelde, JL1
Bertrand, L1
Gallagher, KP1
McClanahan, TB1
Martin, BJ1
Saganek, LJ1
Ignasiak, DP1
Mertz, TE1
Van Wylen, DG2
Vinten-Johansen, J1
Tan, ZT1
Wang, XW1
Zughaib, ME1
Jeroudi, MO1
Sun, JZ1
Sekili, S1
Tang, XL1
Bolli, R1
Sandhu, GS1
Burrier, AC1
Janero, DR1
Xu, J1
Tong, H1
Hurt, CM1
Pelleg, A1
Lasley, RD1
Mentzer, RM1
Khatchikian, G1
Zweier, JL1
Mallet, RT1
Lee, SC1
Downey, HF1
Manthei, SA1
Reiling, CM1
Maddox, RP1
Rebeyka, IM1
Lekven, J1
Hirai, K1
Ashraf, M1
Schreieck, J1
Richardt, G1
Demaison, L1
Moreau, D1
Vergely-Vandriesse, C1
Grégoire, S1
Degois, M1
Rochette, L1

Reviews

1 review available for adenine and Heart Disease, Ischemic

ArticleYear
Does adenosine deaminase inhibition protect ischemic myocardium?
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Humans; In Vitro Techniques; My

1994

Other Studies

24 other studies available for adenine and Heart Disease, Ischemic

ArticleYear
Autophagy during left ventricular redilation after ventriculoplasty: Insights from a rat model of ischemic cardiomyopathy.
    The Journal of thoracic and cardiovascular surgery, 2022, Volume: 163, Issue:1

    Topics: Adenine; Animals; Autophagy; Autophagy-Related Proteins; Cardiomyopathy, Dilated; Cardiomyoplasty; C

2022
Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: hot shot drug delivery befor
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 146, Issue:4

    Topics: Adenine; Adenosine Triphosphate; Animals; Cold Ischemia; Disease Models, Animal; Dogs; Equilibrative

2013
Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Adenine; Animals; Blood Pressure; Cardiotonic Agents; Drug Design; Heart Rate; Hydrogen Sulfide; Mal

2016
Activation of volume-sensitive Cl- channel mediates autophagy-related cell death in myocardial ischaemia/reperfusion injury.
    Oncotarget, 2016, Jun-28, Volume: 7, Issue:26

    Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Proliferation; Chloride Channels; Cytokines; Hydrogen-I

2016
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 144, Issue:1

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Chromatography, High Pressure Liquid; Constriction

2012
Tracer adenosine: a novel myocardial flow marker.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:4

    Topics: Adenine; Adenosine; Alprostadil; Animals; Carbon Radioisotopes; Coronary Circulation; Dogs; Isotope

2003
Modest actomyosin energy conservation increases myocardial postischemic function.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:3

    Topics: Actomyosin; Adenine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Creatine;

2005
Age-related changes in ischemic tolerance in male and female mouse hearts.
    Journal of molecular and cellular cardiology, 2005, Volume: 38, Issue:2

    Topics: Adenine; Adenosine Diphosphate; Aging; Animals; Collagen; Coronary Vessels; Female; Heart; Hydro-Lya

2005
Role of the alpha2-isoform of AMP-activated protein kinase in the metabolic response of the heart to no-flow ischemia.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Acetyl-CoA Carboxylase; Adenine; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Fat

2006
Verapamil, ribose and adenine enhance resynthesis of postischemic myocardial ATP.
    Life sciences, 1994, Volume: 55, Issue:18

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Calcium; Heart; Male; Myocardial Isch

1994
Nucleoside trapping during reperfusion prevents ventricular dysfunction, "stunning," in absence of adenosine. Possible separation between ischemic and reperfusion injury.
    The Journal of thoracic and cardiovascular surgery, 1994, Volume: 108, Issue:2

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; B

1994
Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA.
    Journal of cardiac surgery, 1994, Volume: 9, Issue:3 Suppl

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dogs; Female; Heart; Inosi

1994
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
    Circulation, 1993, Volume: 88, Issue:5 Pt 1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; M

1993
Adenosine deaminase inhibitors attenuate ischemic injury and preserve energy balance in isolated guinea pig heart.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Coformycin; Creatine Kinase; Energy Metabolism; Gu

1993
Endogenous adenosine, A1 adenosine receptor, and pertussis toxin sensitive guanine nucleotide binding protein mediate hypoxia induced AV nodal conduction block in guinea pig heart in vivo.
    Cardiovascular research, 1993, Volume: 27, Issue:1

    Topics: Adenine; Adenosine; Animals; Female; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Block; Male; My

1993
Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia.
    Cardiovascular research, 1993, Volume: 27, Issue:1

    Topics: Adenine; Adenosine; Animals; Glucose; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardia

1993
Adenosine deaminase inhibition prevents free radical-mediated injury in the postischemic heart.
    The Journal of biological chemistry, 1996, Apr-26, Volume: 271, Issue:17

    Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Electro

1996
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
    Cardiovascular research, 1996, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproter

1996
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
    Cardiovascular research, 1998, Volume: 37, Issue:1

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High

1998
Role of nucleoside transport and purine release in a rabbit model of myocardial stunning.
    Molecular and cellular biochemistry, 1998, Volume: 180, Issue:1-2

    Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Carrier Proteins; Dogs; Enzym

1998
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: role of purine release in ischemic and reperfusion injury.
    Molecular and cellular biochemistry, 1998, Volume: 180, Issue:1-2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Carrier Proteins;

1998
Modulation of adenosine effects in attenuation of ischemia and reperfusion injury in rat heart.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:9

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Heart; Heart Rate; I

1998
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiogra

1999
Effects of dietary polyunsaturated fatty acids and hepatic steatosis on the functioning of isolated working rat heart under normoxic conditions and during post-ischemic reperfusion.
    Molecular and cellular biochemistry, 2001, Volume: 224, Issue:1-2

    Topics: Adenine; Animals; Aorta; Ascorbic Acid; Body Weight; Cardiac Output; Cell Respiration; Cholesterol,

2001