Page last updated: 2024-10-16

adenine and Hair Diseases

adenine has been researched along with Hair Diseases in 2 studies

Hair Diseases: Diseases affecting the orderly growth and persistence of hair.

Research Excerpts

ExcerptRelevanceReference

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Y1
Han, D1
Zhang, H1
Liu, H1
Wong, S1
Zhao, N1
Qiu, L1
Feng, H1
Bitar, C1
Farooqui, MZ1
Valdez, J1
Saba, NS1
Soto, S1
Bray, A1
Marti, G1
Wiestner, A1
Cowen, EW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Study of PCI-32765 for Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and Are Older Than 65 or Have a 17p Deletion[NCT01500733]Phase 286 participants (Actual)Interventional2012-01-05Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Response Rate at 6 Months

"The primary endpoint was response after 6 cycles of therapy. Overall response rate was calculated as complete response plus partial response, based on the International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2008 criteria.as follows:~Complete response (CR): all group A and group B criteria are met~Group A criteria: resolution of enlarged lymph nodes, normal size spleen and liver, absolute lymphocyte count < 4,000/uL, normocellular bone marrow with < 30% lymphocytes without nodules~Group B criteria: improved blood count (platelet count > 100,000/uL, hemoglobin > 11.0 g/dL, neutrophils > 1,500/uL)~Partial response (PR): at least 2 of the group A criteria plus one of the group B criteria are met~Group A criteria: >=50% decrease in target lymph nodes, >=50% decrease in spleen size, >=50% decrease in liver size, 50% reduction in marrow infiltrates~Group B criteria: platelet count > 100,000/uL, hemoglobin > 11.0 g/dL, neutrophils > 1,500/uL" (NCT01500733)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Elderly Cohort93.9
TP53 Cohort95.8

Trials

1 trial available for adenine and Hair Diseases

ArticleYear
Hair and Nail Changes During Long-term Therapy With Ibrutinib for Chronic Lymphocytic Leukemia.
    JAMA dermatology, 2016, 06-01, Volume: 152, Issue:6

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Antineoplastic Agents; Female

2016

Other Studies

1 other study available for adenine and Hair Diseases

ArticleYear
Morphological analyses and a novel de novo DLX3 mutation associated with tricho-dento-osseous syndrome in a Chinese family.
    European journal of oral sciences, 2015, Volume: 123, Issue:4

    Topics: Absorptiometry, Photon; Adenine; Adult; Bone Density; China; Conserved Sequence; Craniofacial Abnorm

2015