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adenine and Graves Disease

adenine has been researched along with Graves Disease in 6 studies

Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

Research Excerpts

ExcerptRelevanceReference
"We studied 27 patients with untreated Graves' disease, 10 with Graves' disease complicated by ophthalmopathy (all on antithyroid medication), 11 with Hashimoto's thyroiditis, five with multinodular goitre, one with thyroid carcinoma, 23 with type 1 diabetes mellitus, 19 with other autoimmune diseases and 10 controls."1.28Measurement of thyroid-stimulating immunoglobulins by incorporation of tritiated-adenine into intact FRTL-5 cells: a viable alternative to radioimmunoassay for the measurement of cAMP. ( Colman, PG; Frauman, AG; Leedman, PJ; Michelangeli, VP, 1992)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ho, NA1
Schmidt, RE1
Behrens, G1
Takara, M1
Kouki, T2
DeGroot, LJ2
Fukutani, T1
Hiromatsu, Y1
Kaku, H1
Miyake, I1
Mukai, T1
Imamura, Y1
Kohno, S1
Takane, N1
Shoji, S1
Otabe, S1
Yamada, K1
Sawai, Y1
Gardine, CA1
Fisfalen, ME1
Alegre, ML1
Leedman, PJ1
Frauman, AG1
Colman, PG1
Michelangeli, VP1
Kendall-Taylor, P1

Other Studies

6 other studies available for adenine and Graves Disease

ArticleYear
[HIV-therapy-associated immune reconstitution syndrome presenting as immunogenic hyperthyroidism].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:23

    Topics: Adenine; Alkynes; Anti-HIV Agents; Autoantibodies; Benzoxazines; Cyclopropanes; Deoxycytidine; Diagn

2010
CTLA-4 AT-repeat polymorphism reduces the inhibitory function of CTLA-4 in Graves' disease.
    Thyroid : official journal of the American Thyroid Association, 2003, Volume: 13, Issue:12

    Topics: Adenine; Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Case

2003
A polymorphism of interferon-gamma gene associated with changes of anti-thyrotropin receptor antibodies induced by antithyroid drug treatment for Graves' disease in Japanese patients.
    Thyroid : official journal of the American Thyroid Association, 2004, Volume: 14, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antithyroid Agents; Asian People; Autoantibodie

2004
CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Dec-01, Volume: 165, Issue:11

    Topics: Abatacept; Adenine; Adjuvants, Immunologic; Alleles; Antibodies, Monoclonal; Antigens, CD; Antigens,

2000
Measurement of thyroid-stimulating immunoglobulins by incorporation of tritiated-adenine into intact FRTL-5 cells: a viable alternative to radioimmunoassay for the measurement of cAMP.
    Clinical endocrinology, 1992, Volume: 37, Issue:6

    Topics: Adenine; Animals; Autoantibodies; Biological Assay; Cells, Cultured; Cyclic AMP; Epithelium; Graves

1992
Effects of long-acting thyroid stimulator (LATS) and LATS protector on human thyroid adenyl cyclase activity.
    British medical journal, 1973, Jul-14, Volume: 3, Issue:5871

    Topics: Adenine; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Enzyme Activation; Graves Disease; Hum

1973