adenine has been researched along with Glycosuria in 11 studies
Glycosuria: The appearance of an abnormally large amount of GLUCOSE in the urine, such as more than 500 mg/day in adults. It can be due to HYPERGLYCEMIA or genetic defects in renal reabsorption (RENAL GLYCOSURIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy, safety, and the tolerability of two dosing regimens of ADV (10 mg daily or 30 mg daily), two double-blind, placebo-controlled studies were performed in patients with chronic hepatitis B and compensated liver disease who were not undergoing current treatment and who had evidence of hepatitis B virus (HBV) replication." | 6.71 | Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: two double-blind, randomized, placebo-controlled studies. ( Arterbrun, S; Brosgart, CL; Currie, G; Deray, G; Hadziyannis, SJ; Hulot, JS; Izzedine, H; Launay-Vacher, V; Marcellini, P; Westland, C, 2004) |
| "To investigate the efficacy, safety, and the tolerability of two dosing regimens of ADV (10 mg daily or 30 mg daily), two double-blind, placebo-controlled studies were performed in patients with chronic hepatitis B and compensated liver disease who were not undergoing current treatment and who had evidence of hepatitis B virus (HBV) replication." | 2.71 | Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: two double-blind, randomized, placebo-controlled studies. ( Arterbrun, S; Brosgart, CL; Currie, G; Deray, G; Hadziyannis, SJ; Hulot, JS; Izzedine, H; Launay-Vacher, V; Marcellini, P; Westland, C, 2004) |
| " Renal biopsy revealed toxic acute tubular necrosis, with distinctive proximal tubular eosinophilic inclusions representing giant mitochondria visible by light microscopy." | 1.36 | Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities. ( D'Agati, VD; Herlitz, LC; Markowitz, GS; Mohan, S; Radhakrishnan, J; Stokes, MB, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Yi, D | 1 |
| Sun, W | 1 |
| Wang, C | 1 |
| Lv, Y | 1 |
| Li, X | 1 |
| Liang, S | 1 |
| Liang, D | 1 |
| Xu, F | 1 |
| Zhu, X | 1 |
| Zeng, C | 1 |
| Woodward, CL | 1 |
| Hall, AM | 1 |
| Williams, IG | 1 |
| Madge, S | 1 |
| Copas, A | 1 |
| Nair, D | 1 |
| Edwards, SG | 1 |
| Johnson, MA | 1 |
| Connolly, JO | 1 |
| Herlitz, LC | 1 |
| Mohan, S | 1 |
| Stokes, MB | 1 |
| Radhakrishnan, J | 1 |
| D'Agati, VD | 1 |
| Markowitz, GS | 1 |
| Perazella, MA | 1 |
| Calza, L | 1 |
| Trapani, F | 1 |
| Salvadori, C | 1 |
| Magistrelli, E | 1 |
| Manfredi, R | 1 |
| Colangeli, V | 1 |
| Di Bari, MA | 1 |
| Borderi, M | 1 |
| Viale, P | 1 |
| Karras, A | 1 |
| Lafaurie, M | 1 |
| Furco, A | 1 |
| Bourgarit, A | 1 |
| Droz, D | 1 |
| Sereni, D | 1 |
| Legendre, C | 1 |
| Martinez, F | 1 |
| Molina, JM | 1 |
| Peyrière, H | 1 |
| Reynes, J | 1 |
| Rouanet, I | 1 |
| Daniel, N | 1 |
| de Boever, CM | 1 |
| Mauboussin, JM | 1 |
| Leray, H | 1 |
| Moachon, L | 1 |
| Vincent, D | 1 |
| Salmon-Céron, D | 1 |
| Van Rompay, KK | 1 |
| Brignolo, LL | 1 |
| Meyer, DJ | 1 |
| Jerome, C | 1 |
| Tarara, R | 1 |
| Spinner, A | 1 |
| Hamilton, M | 1 |
| Hirst, LL | 1 |
| Bennett, DR | 1 |
| Canfield, DR | 1 |
| Dearman, TG | 1 |
| Von Morgenland, W | 1 |
| Allen, PC | 1 |
| Valverde, C | 1 |
| Castillo, AB | 1 |
| Martin, RB | 1 |
| Samii, VF | 1 |
| Bendele, R | 1 |
| Desjardins, J | 1 |
| Marthas, ML | 1 |
| Pedersen, NC | 1 |
| Bischofberger, N | 1 |
| Izzedine, H | 1 |
| Hulot, JS | 1 |
| Launay-Vacher, V | 1 |
| Marcellini, P | 1 |
| Hadziyannis, SJ | 1 |
| Currie, G | 1 |
| Brosgart, CL | 1 |
| Westland, C | 1 |
| Arterbrun, S | 1 |
| Deray, G | 1 |
| Fine, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Drug Therapy and Co-Morbidities on the Development of Renal Impairment in HIV-Infected Patients[NCT00551655] | 684 participants (Actual) | Observational | 2007-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for adenine and Glycosuria
| Article | Year |
|---|---|
Editorial comment: tenofovir nephrotoxicity--vigilance required.
Topics: Adenine; Fanconi Syndrome; Glycosuria; HIV Infections; Humans; Hypokalemia; Hypophosphatemia; Organo | 2005 |
1 trial available for adenine and Glycosuria
| Article | Year |
|---|---|
Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: two double-blind, randomized, placebo-controlled studies.
Topics: Adenine; Adult; Antiviral Agents; Creatinine; Double-Blind Method; Female; Glycosuria; Hematuria; He | 2004 |
9 other studies available for adenine and Glycosuria
| Article | Year |
|---|---|
Retrospective analysis of the clinical characteristics of adefovir dipivoxil-induced Fanconi's syndrome in the Chinese population.
Topics: Adenine; Adult; Aged; Alkaline Phosphatase; Asian People; Bone Density; Fanconi Syndrome; Female; Gl | 2020 |
The clinical and pathological features of adefovir dipivoxil-related renal impairment
.
Topics: Adenine; Adult; Antiviral Agents; Creatinine; Female; Glycosuria; Hematuria; Hepatitis B, Chronic; H | 2019 |
Tenofovir-associated renal and bone toxicity.
Topics: Adenine; Adult; Anti-HIV Agents; Creatinine; Fanconi Syndrome; Female; Glycosuria; HIV Infections; H | 2009 |
Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities.
Topics: Acute Kidney Injury; Adenine; Adult; Anti-HIV Agents; Biopsy; Drug Administration Schedule; Female; | 2010 |
Tenofovir-induced kidney disease: an acquired renal tubular mitochondriopathy.
Topics: Acute Kidney Injury; Adenine; Animals; Anti-HIV Agents; Drug Administration Schedule; Glycosuria; HI | 2010 |
Incidence of renal toxicity in HIV-infected, antiretroviral-naïve patients starting tenofovir/emtricitabine associated with efavirenz, atazanavir/ritonavir, or lopinavir/ritonavir.
Topics: Adenine; Adult; Alkynes; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabi | 2013 |
Tenofovir-related nephrotoxicity in human immunodeficiency virus-infected patients: three cases of renal failure, Fanconi syndrome, and nephrogenic diabetes insipidus.
Topics: Acidosis; Adenine; Adult; Anti-HIV Agents; Creatinine; Diabetes Insipidus, Nephrogenic; Drug Monitor | 2003 |
Renal tubular dysfunction associated with tenofovir therapy: report of 7 cases.
Topics: Adenine; Adult; Anti-HIV Agents; Body Weight; Drug Therapy, Combination; Female; Glycosuria; Humans; | 2004 |
Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy)propyl]adenine (tenofovir) to newborn and infant rhesus macaques.
Topics: Absorptiometry, Photon; Adenine; Animals; Animals, Newborn; Anti-HIV Agents; Area Under Curve; Blood | 2004 |