Page last updated: 2024-10-16

adenine and Glioma

adenine has been researched along with Glioma in 42 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Mesoporous silica nanoparticles (MSNPs) of a small diameter were loaded with the anticancer drug temozolomide (TMZ), coated with polydopamine (PDA), and conjugated with Asn-Gly-Arg (NGR) for use in the treatment of glioma."7.91Combination of 3-methyladenine therapy and Asn-Gly-Arg (NGR)-modified mesoporous silica nanoparticles loaded with temozolomide for glioma therapy in vitro. ( Cheng, Y; Huang, N; Huang, Q; Tan, Y; Tang, M; Zhang, P; Zhang, X; Zhao, G, 2019)
" To clarify the antitumor mechanism of caffeic acid phenethyl ester (CAPE) and achieve increased therapeutic efficiency, we investigated the potential roles of AMPK and autophagy in CAPE treatment against C6 glioma cells."7.77Inhibition of AMPK-associated autophagy enhances caffeic acid phenethyl ester-induced cell death in C6 glioma cells. ( Cheng, KT; Huang, SH; Huang, ST; Kao, YT; Lee, CM; Lin, CM; Wu, JY; Yu, SH, 2011)
" In this study, we present that temozolomide (TMZ), a new alkylating agent, inhibited the viability of malignant glioma cells in a dose-dependent manner and induced G2/M arrest."7.72Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. ( Germano, IM; Ito, H; Kanzawa, T; Komata, T; Kondo, S; Kondo, Y, 2004)
"Malignant glioma is the most aggressive brain tumor."5.46Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. ( Chen, JT; Chen, RM; Cheng, BC; Chio, CC; Liu, SH; Yang, ST, 2017)
"Quercetin can inhibit cell viability and induce autophagy of U87 and U251 glioma cells in a dose-dependent manner."5.43Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells. ( Bi, Y; Gao, D; Hou, X; Li, C; Liu, H; Liu, Y; Liu, Z; Peng, F; Shen, C; Shi, C; Wang, K; Wang, X; Wu, J; Zhang, J; Zhao, B; Zhao, S; Zheng, Z; Zhong, C; Zou, H, 2016)
"Mesoporous silica nanoparticles (MSNPs) of a small diameter were loaded with the anticancer drug temozolomide (TMZ), coated with polydopamine (PDA), and conjugated with Asn-Gly-Arg (NGR) for use in the treatment of glioma."3.91Combination of 3-methyladenine therapy and Asn-Gly-Arg (NGR)-modified mesoporous silica nanoparticles loaded with temozolomide for glioma therapy in vitro. ( Cheng, Y; Huang, N; Huang, Q; Tan, Y; Tang, M; Zhang, P; Zhang, X; Zhao, G, 2019)
" To clarify the antitumor mechanism of caffeic acid phenethyl ester (CAPE) and achieve increased therapeutic efficiency, we investigated the potential roles of AMPK and autophagy in CAPE treatment against C6 glioma cells."3.77Inhibition of AMPK-associated autophagy enhances caffeic acid phenethyl ester-induced cell death in C6 glioma cells. ( Cheng, KT; Huang, SH; Huang, ST; Kao, YT; Lee, CM; Lin, CM; Wu, JY; Yu, SH, 2011)
" In the present study, the authors analyzed the effect of pitavastatin as a potential inhibitor of NF-kappaB activation on the radiosensitivity of A172, U87, and U251 human glioma cell lines."3.75Induction of autophagic cell death and radiosensitization by the pharmacological inhibition of nuclear factor-kappa B activation in human glioma cell lines. ( Endo, S; Hayakawa, Y; Hayashi, N; Kamiyama, H; Kitajima, I; Kurimoto, M; Nagai, S; Tsuboi, Y, 2009)
"We present here a suicide therapy against malignant gliomas based on the transfer to tumor cells of a gene encoding a beta-glucosidase, linamarase (lis), which in the presence of the innocuous substrate linamarin (lin) produces cyanide, blocking the mitochondrial respiratory chain."3.74Glioma regression in vitro and in vivo by a suicide combined treatment. ( García-Escudero, V; Gargini, R; Izquierdo, M, 2008)
" In this study, we present that temozolomide (TMZ), a new alkylating agent, inhibited the viability of malignant glioma cells in a dose-dependent manner and induced G2/M arrest."3.72Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. ( Germano, IM; Ito, H; Kanzawa, T; Komata, T; Kondo, S; Kondo, Y, 2004)
" We show here that antisense suppression of WRN in two human glioma cell lines reproduces hallmarks of the drug cytotoxicity profile of WS cells, namely, hypersensitivity to 4-nitroquinoline 1-oxide, camptothecin and hydroxyurea."3.72The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. ( Blank, A; Bobola, MS; D Kolstoe, D; Gold, B; Loeb, LA; Meade, EH; Rabinovitch, PS; Silber, JR; Varadarajan, S, 2004)
" However, chromosome losses do not seem to directly cause the metabolic alterations by gene dosage effect."2.38[Chromosome abnormalities and adenine metabolism in human glial tumors]. ( Bardot, V; Delattre, JY; Dutrillaux, AM; Dutrillaux, B; Luccioni, C; Poisson, M; Vega, F, 1992)
" Here we report the preclinical potential of a novel, orally bioavailable PI3K/mTOR dual inhibitor, DS7423 (hereafter DS), in in-vitro and in-vivo studies."1.46Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma. ( Gao, F; Hirota, Y; Kaul, I; Koul, D; Koyama, K; Nakayama, K; Saito, N; Setoguchi, M; Shiose, Y; Sulman, EP; Wang, S; Wu, S; Yung, WKA; Zheng, S, 2017)
"Malignant glioma is the most common primary brain tumor in adults and has a poor prognosis."1.46High expression of Bruton's tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma. ( Hua, L; Liu, X; Niu, M; Shan, QQ; Tu, Y; Xie, P; Yu, R; Yue, C; Zhou, T, 2017)
"Glioma is the most devastating cancer in the brain and has a poor prognosis in adults."1.46Isogambogenic Acid Inhibits the Growth of Glioma Through Activation of the AMPK-mTOR Pathway. ( Gao, M; Hou, X; Liu, H; Liu, Y; Peng, F; Shu, M; Wang, K; Wang, X; Xue, L; Ye, J; Zhao, B; Zhao, S; Zhao, W; Zhong, C, 2017)
"Malignant glioma is the most aggressive brain tumor."1.46Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. ( Chen, JT; Chen, RM; Cheng, BC; Chio, CC; Liu, SH; Yang, ST, 2017)
"Quercetin can inhibit cell viability and induce autophagy of U87 and U251 glioma cells in a dose-dependent manner."1.43Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells. ( Bi, Y; Gao, D; Hou, X; Li, C; Liu, H; Liu, Y; Liu, Z; Peng, F; Shen, C; Shi, C; Wang, K; Wang, X; Wu, J; Zhang, J; Zhao, B; Zhao, S; Zheng, Z; Zhong, C; Zou, H, 2016)
"Malignant gliomas are common primary tumors of the central nervous system."1.35Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells. ( Akiyama, Y; Bögler, O; Fujiwara, K; Kondo, S; Moritake, K; Shingu, T; Shinojima, N; Tamada, Y; Yokoyama, T, 2009)
"Adenosine release was investigated by first loading cells with [(3)H]adenine to label adenine nucleotide pools."1.31Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions. ( Baldwin, SA; Cass, CE; LaRivière, CG; Parkinson, FE; Sinclair, CJ; Young, JD, 2000)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.38)18.7374
1990's4 (9.52)18.2507
2000's9 (21.43)29.6817
2010's24 (57.14)24.3611
2020's4 (9.52)2.80

Authors

AuthorsStudies
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
Yan, Z1
Zhou, L1
Zhao, Y4
Wang, J7
Huang, L2
Hu, K1
Liu, H6
Wang, H5
Guo, Z1
Song, Y1
Huang, H4
Yang, R1
Owen, TW1
Al-Kaysi, RO1
Bardeen, CJ1
Cheng, Q1
Wu, S2
Cheng, T1
Zhou, X1
Wang, B4
Zhang, Q4
Wu, X2
Yao, Y3
Ochiai, T1
Ishiguro, H2
Nakano, R2
Kubota, Y2
Hara, M1
Sunada, K1
Hashimoto, K1
Kajioka, J1
Fujishima, A1
Jiao, J3
Gai, QY3
Wang, W4
Zang, YP2
Niu, LL2
Fu, YJ3
Wang, X7
Yao, LP1
Qin, QP1
Wang, ZY1
Liu, J6
Aleksic Sabo, V1
Knezevic, P1
Borges-Argáez, R1
Chan-Balan, R1
Cetina-Montejo, L1
Ayora-Talavera, G1
Sansores-Peraza, P1
Gómez-Carballo, J1
Cáceres-Farfán, M1
Jang, J1
Akin, D1
Bashir, R1
Yu, Z1
Zhu, J2
Jiang, H1
He, C2
Xiao, Z1
Xu, J2
Sun, Q1
Han, D1
Lei, H1
Zhao, K2
Zhu, L1
Li, X4
Fu, H2
Wilson, BK1
Step, DL1
Maxwell, CL1
Gifford, CA1
Richards, CJ1
Krehbiel, CR1
Warner, JM1
Doerr, AJ1
Erickson, GE1
Guretzky, JA1
Rasby, RJ1
Watson, AK1
Klopfenstein, TJ1
Sun, Y4
Liu, Z4
Pham, TD1
Lee, BK1
Yang, FC1
Wu, KH1
Lin, WP1
Hu, MK1
Lin, L3
Shao, J1
Sun, M1
Xu, G1
Zhang, X7
Xu, N1
Wang, R2
Liu, S1
He, H1
Dong, X2
Yang, M2
Yang, Q1
Duan, S1
Yu, Y2
Han, J2
Zhang, C3
Chen, L2
Yang, X1
Li, W3
Wang, T2
Campbell, DA1
Gao, K1
Zager, RA1
Johnson, ACM1
Guillem, A1
Keyser, J1
Singh, B1
Steubl, D1
Schneider, MP1
Meiselbach, H1
Nadal, J1
Schmid, MC1
Saritas, T1
Krane, V1
Sommerer, C1
Baid-Agrawal, S1
Voelkl, J1
Kotsis, F1
Köttgen, A1
Eckardt, KU1
Scherberich, JE1
Li, H4
Yao, L2
Sun, L4
Zhu, Z1
Naren, N1
Zhang, XX2
Gentile, GL1
Rupert, AS1
Carrasco, LI1
Garcia, EM1
Kumar, NG1
Walsh, SW1
Jefferson, KK1
Guest, RL1
Samé Guerra, D1
Wissler, M1
Grimm, J1
Silhavy, TJ1
Lee, JH2
Yoo, JS1
Kim, Y1
Kim, JS2
Lee, EJ1
Roe, JH1
Delorme, M1
Bouchard, PA1
Simon, M1
Simard, S1
Lellouche, F1
D'Urzo, KA1
Mok, F1
D'Urzo, AD1
Koneru, B1
Lopez, G1
Farooqi, A1
Conkrite, KL1
Nguyen, TH1
Macha, SJ1
Modi, A1
Rokita, JL1
Urias, E1
Hindle, A1
Davidson, H1
Mccoy, K1
Nance, J1
Yazdani, V1
Irwin, MS1
Yang, S1
Wheeler, DA1
Maris, JM1
Diskin, SJ1
Reynolds, CP1
Abhilash, L1
Kalliyil, A1
Sheeba, V1
Hartley, AM2
Meunier, B2
Pinotsis, N1
Maréchal, A2
Xu, JY1
Genko, N1
Haraux, F1
Rich, PR1
Kamalanathan, M1
Doyle, SM1
Xu, C1
Achberger, AM1
Wade, TL1
Schwehr, K1
Santschi, PH1
Sylvan, JB1
Quigg, A1
Leong, W1
Xu, W2
Gao, S1
Zhai, X1
Wang, C2
Gilson, E1
Ye, J2
Lu, Y1
Yan, R1
Zhang, Y6
Hu, Z1
You, Q1
Cai, Q1
Yang, D1
Gu, S1
Dai, H1
Zhao, X1
Gui, C1
Gui, J1
Wu, PK1
Hong, SK1
Starenki, D1
Oshima, K1
Shao, H1
Gestwicki, JE1
Tsai, S1
Park, JI1
Wang, Y7
Zhao, R1
Gu, Z1
Dong, C2
Guo, G1
Li, L4
Barrett, HE1
Meester, EJ1
van Gaalen, K1
van der Heiden, K1
Krenning, BJ1
Beekman, FJ1
de Blois, E1
de Swart, J1
Verhagen, HJ1
Maina, T1
Nock, BA1
Norenberg, JP1
de Jong, M1
Gijsen, FJH1
Bernsen, MR1
Martínez-Milla, J1
Galán-Arriola, C1
Carnero, M1
Cobiella, J1
Pérez-Camargo, D1
Bautista-Hernández, V1
Rigol, M1
Solanes, N1
Villena-Gutierrez, R1
Lobo, M1
Mateo, J1
Vilchez-Tschischke, JP1
Salinas, B1
Cussó, L1
López, GJ1
Fuster, V1
Desco, M1
Sanchez-González, J1
Ibanez, B1
van den Berg, P1
Schweitzer, DH1
van Haard, PMM1
Geusens, PP1
van den Bergh, JP1
Zhu, X1
Huang, X2
Xu, H2
Yang, G2
Lin, Z1
Salem, HF1
Nafady, MM1
Kharshoum, RM1
Abd El-Ghafar, OA1
Farouk, HO1
Domiciano, D1
Nery, FC1
de Carvalho, PA1
Prudente, DO1
de Souza, LB1
Chalfun-Júnior, A1
Paiva, R1
Marchiori, PER1
Lu, M2
An, Z1
Jiang, J2
Li, J7
Du, S1
Zhou, H1
Cui, J1
Wu, W1
Liu, Y9
Song, J1
Lian, Q1
Uddin Ahmad, Z1
Gang, DD1
Konggidinata, MI1
Gallo, AA1
Zappi, ME1
Yang, TWW1
Johari, Y1
Burton, PR1
Earnest, A1
Shaw, K1
Hare, JL1
Brown, WA1
Kim, GA1
Han, S1
Choi, GH1
Choi, J1
Lim, YS1
Gallo, A1
Cancelli, C1
Ceron, E1
Covino, M1
Capoluongo, E1
Pocino, K1
Ianiro, G1
Cammarota, G1
Gasbarrini, A1
Montalto, M1
Somasundar, Y1
Lu, IC1
Mills, MR1
Qian, LY1
Olivares, X1
Ryabov, AD1
Collins, TJ1
Zhao, L1
Doddipatla, S1
Thomas, AM1
Nikolayev, AA1
Galimova, GR1
Azyazov, VN1
Mebel, AM1
Kaiser, RI1
Guo, S1
Yang, P1
Yu, X2
Wu, Y2
Zhang, H3
Yu, B2
Han, B1
George, MW1
Moor, MB1
Bonny, O1
Langenberg, E1
Paik, H1
Smith, EH1
Nair, HP1
Hanke, I1
Ganschow, S1
Catalan, G1
Domingo, N1
Schlom, DG1
Assefa, MK1
Wu, G2
Hayton, TW1
Becker, B1
Enikeev, D1
Netsch, C1
Gross, AJ1
Laukhtina, E1
Glybochko, P1
Rapoport, L1
Herrmann, TRW1
Taratkin, M1
Dai, W1
Shi, J2
Carreno, J1
Kloner, RA1
Pickersgill, NA1
Vetter, JM1
Kim, EH1
Cope, SJ1
Du, K1
Venkatesh, R1
Giardina, JD1
Saad, NES1
Bhayani, SB1
Figenshau, RS1
Eriksson, J1
Landfeldt, E1
Ireland, S1
Jackson, C1
Wyatt, E1
Gaudig, M1
Stancill, JS1
Happ, JT1
Broniowska, KA1
Hogg, N1
Corbett, JA1
Tang, LF1
Bi, YL1
Fan, Y2
Sun, YB1
Wang, AL2
Xiao, BH1
Wang, LF1
Qiu, SW1
Guo, SW1
Wáng, YXJ1
Sun, J2
Chu, S1
Pan, Q1
Li, D2
Zheng, S3
Ma, L1
Wang, L4
Hu, T1
Wang, F1
Han, Z1
Yin, Z1
Ge, X1
Xie, K1
Lei, P1
Dias-Santagata, D1
Lennerz, JK1
Sadow, PM1
Frazier, RP1
Govinda Raju, S1
Henry, D1
Chung, T1
Kherani, J1
Rothenberg, SM1
Wirth, LJ1
Marti, CN1
Choi, NG1
Bae, SJ1
Ni, L1
Luo, X1
Dai, T1
Yang, Y3
Lee, R1
Fleischer, AS1
Wemhoff, AP1
Ford, CR1
Kleppinger, EL1
Helms, K1
Bush, AA1
Luna-Abanto, J1
García Ruiz, L1
Laura Martinez, J1
Álvarez Larraondo, M1
Villoslada Terrones, V1
Dukic, L1
Maric, N1
Simundic, AM1
Chogtu, B1
Ommurugan, B1
Thomson, SR1
Kalthur, SG1
Benidir, M1
El Massoudi, S1
El Ghadraoui, L1
Lazraq, A1
Benjelloun, M1
Errachidi, F1
Cassar, M1
Law, AD1
Chow, ES1
Giebultowicz, JM1
Kretzschmar, D1
Salonurmi, T1
Nabil, H1
Ronkainen, J1
Hyötyläinen, T1
Hautajärvi, H1
Savolainen, MJ1
Tolonen, A1
Orešič, M1
Känsäkoski, P1
Rysä, J1
Hakkola, J1
Hukkanen, J1
Zhu, N1
Li, Y5
Du, Q1
Hao, P1
Cao, X1
Li, CX1
Zhao, S3
Luo, XM1
Feng, JX1
Gonzalez-Cotto, M1
Guo, L1
Karwan, M1
Sen, SK1
Barb, J1
Collado, CJ1
Elloumi, F1
Palmieri, EM1
Boelte, K1
Kolodgie, FD1
Finn, AV1
Biesecker, LG1
McVicar, DW1
Qu, F1
Deng, Z1
Xie, Y2
Tang, J3
Chen, Z3
Luo, W1
Xiong, D1
Zhao, D1
Fang, J1
Zhou, Z1
Niu, PP1
Song, B1
Xu, YM1
Zhang, Z2
Qiu, N1
Yin, J1
Zhang, J5
Guo, W1
Liu, M2
Liu, T2
Chen, D5
Luo, K1
He, Z3
Zheng, G1
Xu, F1
Sun, W1
Yin, F1
van Hest, JCM1
Du, L2
Shi, X1
Kang, S1
Duan, W1
Zhang, S2
Feng, J2
Qi, N1
Shen, G1
Ren, H1
Shang, Q1
Zhao, W3
Yang, Z2
Jiang, X2
Alame, M1
Cornillot, E1
Cacheux, V1
Tosato, G1
Four, M1
De Oliveira, L1
Gofflot, S1
Delvenne, P1
Turtoi, E1
Cabello-Aguilar, S1
Nishiyama, M1
Turtoi, A1
Costes-Martineau, V1
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de Andrea, CE1
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Teijeira, Á1
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Cao, Q1
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Shao, B1
Ma, X1
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Liang, X1
Tie, Y1
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Xie, D1
Wei, Y1
Wei, X2
Dokla, EME1
Fang, CS1
Chu, PC1
Chang, CS1
Abouzid, KAM1
Chen, CS1
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Brzezinska, J1
Dymek, B1
Stanczak, PS1
Mazurkiewicz, M1
Olczak, J1
Nowicka, J1
Dzwonek, K1
Zagozdzon, A1
Golab, J1
Golebiowski, A1
Xin, Z1
Himmelbauer, MK1
Jones, JH1
Enyedy, I1
Gilfillan, R1
Hesson, T1
King, K1
Marcotte, DJ1
Murugan, P1
Santoro, JC1
Gonzalez-Lopez de Turiso, F1
Pedron, J1
Boudot, C1
Brossas, JY1
Pinault, E1
Bourgeade-Delmas, S1
Sournia-Saquet, A1
Boutet-Robinet, E1
Destere, A1
Tronnet, A1
Bergé, J1
Bonduelle, C1
Deraeve, C1
Pratviel, G1
Stigliani, JL1
Paris, L1
Mazier, D1
Corvaisier, S1
Since, M1
Malzert-Fréon, A1
Wyllie, S1
Milne, R1
Fairlamb, AH1
Valentin, A1
Courtioux, B1
Verhaeghe, P1
Fang, X3
Gao, M2
Gao, H1
Bi, W1
Tang, H1
Cui, Y1
Zhang, L3
Fan, H1
Yu, H1
Mathison, CJN1
Chianelli, D1
Rucker, PV1
Nelson, J1
Roland, J1
Huang, Z4
Xie, YF1
Epple, R1
Bursulaya, B1
Lee, C1
Gao, MY1
Shaffer, J1
Briones, S1
Sarkisova, Y1
Galkin, A1
Li, N1
Li, C3
Hua, S2
Kasibhatla, S1
Kinyamu-Akunda, J1
Kikkawa, R1
Molteni, V1
Tellew, JE1
Jin, X1
Pang, B1
Liu, Q3
Liu, X4
Huang, Y2
Josephine Fauci, A1
Ma, Y1
Soo Lee, M1
Yuan, W1
Gao, R1
Qi, H1
Zheng, W1
Yang, F2
Chua, H1
Wang, K3
Ou, Y1
Huang, M1
Zhu, Y1
Yu, J2
Tian, J1
Zhao, M1
Hu, J1
Yao, C1
Zhang, B1
Usawachintachit, M1
Tzou, DT1
Washington, SL1
Hu, W1
Chi, T1
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Lv, Y1
Yuan, R1
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Yang, C2
Qiao, Q1
Liu, SF1
Zhang, WH1
Kolano, L1
Knappe, D1
Volke, D1
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Rombaut, L1
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Kim, SJ1
Lee, JO1
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Park, EC1
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Zhan, P1
Guo, Y1
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Wang, Q2
Kawazoe, Y1
Jena, P1
Sun, Z1
Li, Z2
Liang, H1
Xu, X1
Ma, G1
Huo, X1
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Schwartzer, JJ1
Fiseha, T1
Tamir, Z1
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Wang, P1
Mi, K1
Cheng, J1
Gu, C2
Huang, J3
Sun, HB1
Xing, WQ1
Liu, XB1
Zheng, Y1
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Wang, ZF1
Liu, SL1
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Zhang, RX1
Liu, BX1
Fan, CC1
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Nadeem, M1
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Monti, MC1
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Han, X1
Zhou, Y3
Xue, H1
Zhang, W2
Ruan, Z1
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Lin, S1
Wang, Z3
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Mazumder, D1
Yan, X1
Ma, C1
Tang, Y1
Kong, X2
Lu, J1
Zhang, M1
Vital-Jacome, M1
Cazares-Granillo, M1
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Jacob, SI1
Douair, I1
Maron, L1
Ménard, G1
Rusjan, P1
Sabioni, P1
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Mansouri, E1
Boileau, I1
Laveillé, A1
Capet, M1
Duvauchelle, T1
Schwartz, JC1
Robert, P1
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Xia, Y1
Chen, S2
Luo, M1
Wu, J3
Cai, S1
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Meng, X1
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Ramanitrahasimbola, D1
Cornet, M1
Sfar, S1
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Zhang, YQ1
Li, CY1
Tang, SJ1
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Peng, M1
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Zhang, T2
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Liao, CX1
Gao, WJ1
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Yu, CQ1
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Pang, ZC1
Cong, LM1
Dong, Z1
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Jiang, GH1
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Wang, BY1
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Yong, ZP1
Shan, GL1
Weng, TT1
Yan, SQ1
Gao, GP1
Wei, C1
Tao, FB1
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Yao, T1
Dong, S1
Shi, S1
Feng, YL1
Zhang, YW1
Wang, SP1
Shi, AX1
Operario, D1
Zhang, ZH1
Zhu, XF1
Zaller, N1
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Zhang, HB1
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Hu, C1
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Lan, YL1
Zhao, WJ1
Ou, GY1
Lin, WW1
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Wang, S1
Saito, N1
Kaul, I1
Setoguchi, M1
Nakayama, K1
Koyama, K1
Shiose, Y1
Sulman, EP1
Hirota, Y1
Yung, WKA1
Yue, C1
Niu, M1
Shan, QQ1
Zhou, T1
Tu, Y1
Xie, P1
Hua, L1
Yu, R1
Zhou, W2
Shi, Y2
Wu, Q2
Gimple, RC2
Zhai, K1
Ke, SQ1
Ping, YF2
Feng, H2
Rich, JN2
Yu, JS2
Bao, S2
Bian, XW2
Peng, F2
Shu, M1
Hou, X2
Zhao, B2
Zhong, C2
Xue, L1
Guryanova, OA1
Jiang, T1
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Kim, L1
Kung, HF1
Gupta, P1
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Pandey, HS1
Seth, P1
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Zhang, P1
Tang, M1
Huang, Q2
Zhao, G1
Huang, N1
Tan, Y2
Cheng, Y1
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Wu, JY1
Huang, SH1
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Alojado, ES1
Sinclair, CJ1
LaRivière, CG1
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Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253]Phase 3400 participants (Anticipated)Interventional2015-05-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for adenine and Glioma

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Modulation of untranslated region alternative polyadenylation in glioma tumorigenesis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137

    Topics: 3' Untranslated Regions; Adenine; Animals; Brain Neoplasms; Carcinogenesis; Glioma; Humans; Polyaden

2021
[Chromosome abnormalities and adenine metabolism in human glial tumors].
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Adenine; Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromos

1992

Trials

2 trials available for adenine and Glioma

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Phase II study of amonafide in patients with recurrent glioma.
    Journal of neuro-oncology, 1995, Volume: 23, Issue:1

    Topics: Adenine; Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms;

1995

Other Studies

38 other studies available for adenine and Glioma

ArticleYear
Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:4

    Topics: Adenine; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor;

2021
N6-methyladenine-related genes affect biological behavior and the prognosis of glioma.
    Cancer medicine, 2021, Volume: 10, Issue:1

    Topics: Adenine; Adult; Brain Neoplasms; China; Databases, Nucleic Acid; DNA Methylation; Epigenesis, Geneti

2021
Integrative Analysis of Neuregulin Family Members-Related Tumor Microenvironment for Predicting the Prognosis in Gliomas.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Cancer-A

2021
Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma.
    Oncotarget, 2017, Mar-28, Volume: 8, Issue:13

    Topics: Adenine; Animals; Antineoplastic Agents; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Ce

2017
High expression of Bruton's tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma.
    Journal of experimental & clinical cancer research : CR, 2017, 09-25, Volume: 36, Issue:1

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movem

2017
Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy.
    Cell stem cell, 2017, Nov-02, Volume: 21, Issue:5

    Topics: Adenine; Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Glioma; Humans; Mice

2017
Isogambogenic Acid Inhibits the Growth of Glioma Through Activation of the AMPK-mTOR Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 44, Issue:4

    Topics: Adenine; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Brain

2017
Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance.
    Science translational medicine, 2018, 05-30, Volume: 10, Issue:443

    Topics: Adenine; Animals; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Cytokine Receptor

2018
Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation.
    Biochimica et biophysica acta. General subjects, 2019, Volume: 1863, Issue:3

    Topics: Adenine; Animals; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Chromones; Down-Regulation;

2019
Combination of 3-methyladenine therapy and Asn-Gly-Arg (NGR)-modified mesoporous silica nanoparticles loaded with temozolomide for glioma therapy in vitro.
    Biochemical and biophysical research communications, 2019, 02-05, Volume: 509, Issue:2

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Drug Carriers; Drug Delivery Systems;

2019
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
    Experimental cell research, 2015, Jan-15, Volume: 330, Issue:2

    Topics: Adenine; Apoptosis; Autophagy; Autophagy-Related Protein 5; Brain Neoplasms; Cell Line, Tumor; Gliom

2015
Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:2

    Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 3; Caspases, Initiato

2015
Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:3

    Topics: Adenine; Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chloroquine; Gli

2016
Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway.
    Toxicology and applied pharmacology, 2016, 08-01, Volume: 304

    Topics: Adenine; Animals; Apoptosis; Ascorbic Acid; Autophagy; Biphenyl Compounds; Caspase 3; Cell Line, Tum

2016
Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes.
    Oncotarget, 2016, Oct-25, Volume: 7, Issue:43

    Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Animals; Brain Neoplasms; Cell Line, Tumo

2016
Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway.
    International journal of oncology, 2017, Volume: 50, Issue:3

    Topics: Adenine; Antimutagenic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 3; Cell Hypoxia; Cell

2017
Induction of autophagic cell death and radiosensitization by the pharmacological inhibition of nuclear factor-kappa B activation in human glioma cell lines.
    Journal of neurosurgery, 2009, Volume: 110, Issue:3

    Topics: Adenine; Apoptosis; Autophagy; Cell Line, Tumor; Enzyme Inhibitors; Glioma; Humans; Immunoblotting;

2009
Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells.
    International journal of cancer, 2009, Mar-01, Volume: 124, Issue:5

    Topics: Adenine; Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Benzamides; Brain Neoplasms;

2009
Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Adenine; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain

2009
The effects of dynein inhibition on the autophagic pathway in glioma cells.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2010, Feb-01, Volume: 30, Issue:1

    Topics: Adenine; Amino Acids; Autophagy; Cell Line, Tumor; Dynactin Complex; Dyneins; Enzyme Inhibitors; Gli

2010
Autophagy impairment inhibits differentiation of glioma stem/progenitor cells.
    Brain research, 2010, Feb-08, Volume: 1313

    Topics: Adenine; Autophagy; Blotting, Western; Cadaverine; Cell Differentiation; Cells, Cultured; Central Ne

2010
Gangliosides induce autophagic cell death in astrocytes.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: Adenine; Astrocytes; Autophagy; Cell Death; Cell Line; Gangliosides; Glioma; Humans; Lysosomes; Micr

2010
Amyloid-beta1-42 induces reactive oxygen species-mediated autophagic cell death in U87 and SH-SY5Y cells.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 21, Issue:2

    Topics: Acetylcysteine; Adenine; Amyloid beta-Peptides; Animals; Apoptosis; Apoptosis Regulatory Proteins; A

2010
β-Lapachone-induced reactive oxygen species (ROS) generation mediates autophagic cell death in glioma U87 MG cells.
    Chemico-biological interactions, 2011, Jan-15, Volume: 189, Issue:1-2

    Topics: Adenine; Autophagy; Blotting, Western; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Flow Cyto

2011
Minocycline inhibits the growth of glioma by inducing autophagy.
    Autophagy, 2011, Volume: 7, Issue:2

    Topics: Adenine; Animals; Astrocytes; Autophagy; Cell Line, Tumor; Cell Proliferation; Gene Knockdown Techni

2011
Inhibition of AMPK-associated autophagy enhances caffeic acid phenethyl ester-induced cell death in C6 glioma cells.
    Planta medica, 2011, Volume: 77, Issue:9

    Topics: Adenine; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Caffeic Acids; Cell Death; Ce

2011
Rapamycin induces differentiation of glioma stem/progenitor cells by activating autophagy.
    Chinese journal of cancer, 2011, Volume: 30, Issue:10

    Topics: Adenine; Animals; Antibiotics, Antineoplastic; Autophagy; Brain Neoplasms; Cell Differentiation; Cel

2011
Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo.
    Human gene therapy, 2012, Volume: 23, Issue:6

    Topics: Adenine; Adenoviridae; Adenovirus E1A Proteins; Adjuvants, Immunologic; Animals; Autophagy; Cell Lin

2012
EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:12

    Topics: Adenine; Apoptosis; Autophagy; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Central Nervous S

2013
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells.
    Cell death and differentiation, 2004, Volume: 11, Issue:4

    Topics: Adenine; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Cell Cycle; Cell Line, Tumor; Cell

2004
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function.
    DNA repair, 2004, Jun-03, Volume: 3, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Adenine; Alkylating Agents; Antineoplastic Agents; Apoptosis; Camptothecin

2004
Mild heat shock induces autophagic growth arrest, but not apoptosis in U251-MG and U87-MG human malignant glioma cells.
    Journal of neuro-oncology, 2004, Volume: 68, Issue:2

    Topics: Adenine; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Enzyme

2004
Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells.
    International journal of oncology, 2005, Volume: 26, Issue:5

    Topics: Adenine; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; DNA Damage; Enzyme Inhibitors; Gene Expr

2005
Glioma regression in vitro and in vivo by a suicide combined treatment.
    Molecular cancer research : MCR, 2008, Volume: 6, Issue:3

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Adenine; Animals; Brain Neop

2008
Extracellular acidosis delays cell death against glucose-oxygen deprivation in neuroblastoma x glioma hybrid cells.
    Critical care medicine, 1997, Volume: 25, Issue:5

    Topics: Acidosis; Adenine; Cell Death; Cell Survival; Flow Cytometry; Glioma; Glucose; Hydrogen-Ion Concentr

1997
Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Adenine; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Carrier Proteins; Dose-Response

2000
Drug-induced alterations in morphology and level of cAMP in cultured human glioma cells.
    Experimental cell research, 1975, Oct-15, Volume: 95, Issue:2

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Catecholamines; Cell Line; Cyclic AMP; Cycl

1975
A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens.
    The American journal of pathology, 1992, Volume: 141, Issue:4

    Topics: Adenine; Astrocytoma; Brain Neoplasms; Chromosome Deletion; Cytidine; DNA, Neoplasm; Glioma; Heteroz

1992