adenine and Genetic Predisposition studies

Research Excerpts

Excerpt	Relevance	Reference
"This review assesses the associations of interleukin-8 gene (IL-8) -251A/T (rs4073) and -845T/C (rs2227532) polymorphisms with susceptibility to periodontitis."	8.91	Quantitative assessment of the associations between interleukin-8 polymorphisms and periodontitis susceptibility. ( Chen, X; Ding, C; Huang, J; Zhong, L, 2015)
"Numerous studies in Chinese populations have evaluated the association between the A-6G and A-20C polymorphisms in the promoter region of angiotensinogen gene and hypertension."	8.87	A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis. ( Gu, W; Liu, J; Liu, K; Lou, Y; Niu, Q; Wang, H; Wang, L; Wang, Z; Wen, S; Zhang, J, 2011)
"To investigate the association between the androgen receptor (AR) cytosine, adenine, and guanine (CAG) repeat polymorphisms and endometriosis."	7.85	Androgen receptor cytosine, adenine, and guanine trinucleotide repeat polymorphism in Korean patients with endometriosis: A case-control study. ( Chae, SJ; Choi, HY; Choi, YM; Hwang, K; Kim, JJ; Kim, JM; Lee, GH; Shin, JJ, 2017)
"Adefovir dipivoxil (ADV) was an important cause of adult-onset hypophosphatemic osteomalacia."	7.83	Osteomalacia induced by long-term low-dose adefovir dipivoxil: Clinical characteristics and genetic predictors. ( Fu, WZ; He, JW; Wei, Z; Zhang, ZL, 2016)
"In a Dutch case-control study comprising 123 cases with coronary heart disease (CHD) and 540 controls, we evaluated whether the MTR 2756A>G polymorphism was associated with plasma homocysteine, vitamin B12, folate concentrations, and CHD risk."	7.72	The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study. ( Blom, HJ; den Heijer, M; Klerk, M; Kluijtmans, LA; Kok, FJ; Lievers, KJ; Schouten, EG; Verhoef, P, 2003)
"The angiotensinogen (AGT) gene has been implicated as a risk factor in essential hypertension."	5.33	Angiotensinogen promoter sequence variants in essential hypertension. ( Guruju, M; Kumar, A; Prater, A; Velez, DR; Vinukonda, G; Williams, SM, 2006)
"Endometriosis was documented in 105 women (stage I-II in 33 women and stage III-IV in 72 women)."	5.32	Androgen receptor gene cytosine, adenine, and guanine trinucleotide repeats in patients with endometriosis. ( Di Blasio, AM; Lattuada, D; Odorizzi, MP; Somigliana, E; Viganò, P; Vignali, M, 2004)
"This review assesses the associations of interleukin-8 gene (IL-8) -251A/T (rs4073) and -845T/C (rs2227532) polymorphisms with susceptibility to periodontitis."	4.91	Quantitative assessment of the associations between interleukin-8 polymorphisms and periodontitis susceptibility. ( Chen, X; Ding, C; Huang, J; Zhong, L, 2015)
"Numerous studies in Chinese populations have evaluated the association between the A-6G and A-20C polymorphisms in the promoter region of angiotensinogen gene and hypertension."	4.87	A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis. ( Gu, W; Liu, J; Liu, K; Lou, Y; Niu, Q; Wang, H; Wang, L; Wang, Z; Wen, S; Zhang, J, 2011)
" Given two factors associated with high mutation rates, we tested how many previously known genes match with (i) proximity to telomeres or (ii) high adenine and thymine content in cardiovascular diseases (CVDs) related to vascular stiffening."	4.02	Factors Associated with Mutations: Their Matching Rates to Cardiovascular and Neurological Diseases. ( Hart, C; Hijazi, A; Kim, DG; Lee, C; Lee, PHU; Li, W; Lucas, HB; McKnight, I; Raines, R; Shim, JW, 2021)
"To investigate the association between the androgen receptor (AR) cytosine, adenine, and guanine (CAG) repeat polymorphisms and endometriosis."	3.85	Androgen receptor cytosine, adenine, and guanine trinucleotide repeat polymorphism in Korean patients with endometriosis: A case-control study. ( Chae, SJ; Choi, HY; Choi, YM; Hwang, K; Kim, JJ; Kim, JM; Lee, GH; Shin, JJ, 2017)
"Adefovir dipivoxil (ADV) was an important cause of adult-onset hypophosphatemic osteomalacia."	3.83	Osteomalacia induced by long-term low-dose adefovir dipivoxil: Clinical characteristics and genetic predictors. ( Fu, WZ; He, JW; Wei, Z; Zhang, ZL, 2016)
"To investigate the predictors of proximal kidney tubular dysfunction (PKTD) induced by adefovir dipivoxil (ADV) treatment for chronic hepatitis B."	3.81	Predictors of kidney tubular dysfunction induced by adefovir treatment for chronic hepatitis B. ( Furusyo, N; Harada, Y; Hayashi, J; Hayashi, T; Ihara, T; Ikezaki, H; Murata, M; Ogawa, E; Shimizu, M; Toyoda, K, 2015)
"In a Dutch case-control study comprising 123 cases with coronary heart disease (CHD) and 540 controls, we evaluated whether the MTR 2756A>G polymorphism was associated with plasma homocysteine, vitamin B12, folate concentrations, and CHD risk."	3.72	The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study. ( Blom, HJ; den Heijer, M; Klerk, M; Kluijtmans, LA; Kok, FJ; Lievers, KJ; Schouten, EG; Verhoef, P, 2003)
"Type 2 diabetes is caused by defective insulin secretion and impaired insulin action."	2.71	Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study. ( Eriksson, J; Hämäläinen, H; Ilanne-Parikka, P; Keinänen-Kiukaanniemi, S; Laakso, M; Laukkanen, O; Lindström, J; Pihlajamäki, J; Tuomilehto, J; Uusitupa, M; Valle, TT, 2004)
"However, in the stratified analysis of cancer type, the significant results were only found in lung cancer (dominant model: OR = 0."	2.55	Association between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies. ( Cen, H; Pan, FZ; Shi, C; Wang, MY; Yang, WJ, 2017)
" Dosing antiretroviral agents with kidney metabolism should be adjusted when eGFR is bellow 50 mL/min/1."	2.48	[Kidney and HIV infection]. ( Lescure, FX; Plaisier, E; Ronco, P, 2012)
"Airway inflammation is a key factor in the mechanisms of asthma."	2.42	Mechanisms of asthma. ( Busse, WW; Rosenwasser, LJ, 2003)
"SF3B1 is recurrently mutated in chronic lymphocytic leukemia (CLL), but its role in the pathogenesis of CLL remains elusive."	1.51	A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. ( Brooks, AN; Campagna, DR; Carrasco, RD; Cartun, ZJ; Cibulskis, CL; DeCaprio, JA; Ebert, BL; Fan, J; Fleming, MD; Gambe, RG; Getz, G; Ghia, EM; Herman, SEM; Kipps, TJ; Leshchiner, I; Martinez, AZ; Neuberg, D; Obeng, EA; Rassenti, LZ; Reed, R; Regis, FFD; Sun, J; Taylor-Weiner, A; Ten Hacken, E; Wan, Y; Wang, L; Wiestner, A; Wu, CJ; Yin, S, 2019)
"Highly pathogenic avian influenza viruses with H5 and H7 hemagglutinin (HA) subtypes evolve from low-pathogenic precursors through the acquisition of multiple basic amino acid residues at the HA cleavage site."	1.46	Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin. ( Furuyama, W; Igarashi, M; Kajihara, M; Kishida, N; Manzoor, R; Miyamoto, H; Nao, N; Ohnuma, A; Shigeno, A; Takada, A; Tsuda, Y; Yamagishi, J; Yoshida, R, 2017)
"Waldenström macroglobulinemia (WM) is a B-cell neoplasm manifested by the accumulation of clonal immunoglobulin (Ig)M-secreting lymphoplasmacytic cells."	1.42	How I treat Waldenström macroglobulinemia. ( Treon, SP, 2015)
"Although chronic periodontitis (CP) is a multifactorial condition, few studies have investigated the potential association of gene variants with the outcome of periodontal therapy."	1.40	Clinical outcomes of periodontal therapy are not influenced by the ATC/TTC haplotype in the IL8 gene. ( Anovazzi, G; Cirelli, JA; Corbi, SC; Finoti, LS; Gerlach, RF; Kim, YJ; Marcaccini, AM; Orrico, SR; Scarel-Caminaga, RM; Secolin, R; Tanaka, MH, 2014)
"Sjogren's syndrome is characterized by T-cell infiltration of exocrine glands leading to parenchymal destruction and impaired glandular function."	1.40	Th1 and Th2 polymorphisms in Sjögren's syndrome and rheumatoid arthritis. ( de Albuquerque Tavares Carvalho, A; de Souza, TR; Duarte, ÂP; Gueiros, LA; Leão, JC; Porter, SR, 2014)
"Ameloblastoma is a common benign odontogenic tumour with inherently aggressive behaviour."	1.39	XRCC1 gene polymorphisms and risk of ameloblastoma. ( Boonsuwan, T; Kitkumthorn, N; Mutirangura, A; Yanatatsaneejit, P, 2013)
"A significant increased risk of pancreatic cancer was found to be associated with the CTLA-4 49G>A single-nucleotide polymorphism."	1.38	The functional cytotoxic T lymphocyte-associated Protein 4 49G-to-A genetic variant and risk of pancreatic cancer. ( Kuang, P; Li, H; Liu, L; Sun, T; Tan, W; Tang, X; Wang, L; Yang, M; Yu, D; Yuan, Q; Zhang, X; Zhou, M; Zhou, Y, 2012)
"It has been proposed that individual genetic predisposition may contribute to a persistent apical periodontitis condition."	1.38	Genetic susceptibility to periapical disease: conditional contribution of MMP2 and MMP3 genes to the development of periapical lesions and healing response. ( Deeley, K; Khaliq, S; Letra, A; Menezes-Silva, R; Vieira, AR, 2012)
"One-hundred and fourteen patients with chronic periodontitis and 77 periodontally healthy subjects were genotyped using TaqMan® allelic discrimination assays."	1.37	Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis. ( De Nardin, E; Genco, RJ; Gunsolley, J; Sahingur, SE; Schenkein, HA; Xia, XJ, 2011)
"Coronary heart disease (CHD) and chronic periodontitis (CP) both are multifactorial chronic diseases and related to inflammation."	1.37	Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population? ( Fan, WH; Liu, DL; Sun, SY; Xiao, LM; Xie, CJ; Zhang, JC, 2011)
"Periodontitis is a multifactorial disease in which environmental and genetic determinant factors contribute to individual subjects susceptibility."	1.35	E-selectin and L-selectin polymorphisms in patients with periodontitis. ( Gholami, L; Hajilooi, M; Houshmand, B; Mani-Kashani, K; Rafiei, A, 2009)
"We investigated the genetic predisposition in IL-6 response to coronary revascularization and studied the association between the G-174C polymorphism, IL-6 levels, and clinical outcomes of surgery."	1.33	Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery. ( Barnard, J; Bittar, MN; Carey, JA; Fildes, JE; Hutchinson, IV; Pravica, V; Yonan, N, 2005)
"Oral squamous cell carcinoma (OSCC) is one of the leading cancers in most Asian countries."	1.33	Tumor necrosis factor-alpha promoter polymorphism is associated with susceptibility to oral squamous cell carcinoma. ( Chang, HC; Chang, KW; Lee, YJ; Liu, CJ; Liu, HF; Wong, YK, 2005)
"Comparing women with uterine leiomyomas and controls, no statistically significant differences with respect to allele frequency and genotype distribution were ascertained for ESR1 IVS 1-397 T/C (PvuII) (P=0."	1.33	Genotype distribution of estrogen receptor-alpha, catechol-O-methyltransferase, and cytochrome P450 17 gene polymorphisms in Caucasian women with uterine leiomyomas. ( Bentz, EK; Denschlag, D; Hefler, L; Pietrowski, D; Tempfer, C; Tong, D; Zeillinger, R, 2006)
"The risk of venous thrombosis among 19911G carriers of the prothrombin A19911G polymorphism has not been extensively investigated."	1.33	The association of prothrombin A19911G polymorphism with plasma prothrombin activity and venous thrombosis: results of the MEGA study, a large population-based case-control study. ( Chinthammitr, Y; Doggen, CJ; Rosendaal, FR; Vos, HL, 2006)
"The angiotensinogen (AGT) gene has been implicated as a risk factor in essential hypertension."	1.33	Angiotensinogen promoter sequence variants in essential hypertension. ( Guruju, M; Kumar, A; Prater, A; Velez, DR; Vinukonda, G; Williams, SM, 2006)
"Type 1 diabetes is an autoimmune disease with a Th1 phenotype in which insulin-producing beta-cells in the pancreas are destroyed."	1.32	A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. ( Aud, D; Erlich, HA; Grupe, A; Lazzeroni, LC; Mirel, DB; Noble, JA; Peltz, G; Reynolds, R; Valdes, AM; White, AM, 2003)
"Periodontitis is an inflammatory disease that leads to irreversible attachment loss, bone destruction and eventually tooth loss."	1.32	Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population. ( Buckova, D; Fassmann, A; Holla, LI; Vanek, J; Vasku, A; Znojil, V, 2003)
"Idiopathic Pulmonary Fibrosis (IPF) is a predominantly Th2 mediated disease associated with a paucity of interferon-gamma (IFN-gamma)."	1.32	Analysis of IL-12 p40 subunit gene and IFN-gamma G5644A polymorphisms in Idiopathic Pulmonary Fibrosis. ( du Bois, RM; Latsi, P; Pantelidis, P; Sato, H; Vassilakis, D; Welsh, KI, 2003)
"Endometriosis was documented in 105 women (stage I-II in 33 women and stage III-IV in 72 women)."	1.32	Androgen receptor gene cytosine, adenine, and guanine trinucleotide repeats in patients with endometriosis. ( Di Blasio, AM; Lattuada, D; Odorizzi, MP; Somigliana, E; Viganò, P; Vignali, M, 2004)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (1.59)	18.2507
2000's	60 (47.62)	29.6817
2010's	63 (50.00)	24.3611
2020's	1 (0.79)	2.80

Authors	Studies
Lucas, HB	1
McKnight, I	1
Raines, R	1
Hijazi, A	1
Hart, C	1
Lee, C	1
Kim, DG	1
Li, W	1
Lee, PHU	1
Shim, JW	1
BasuRay, S	1
Smagris, E	1
Cohen, JC	1
Hobbs, HH	1
Yang, WJ	1
Wang, MY	1
Pan, FZ	1
Shi, C	1
Cen, H	1
Shin, JJ	1
Choi, YM	1
Choi, HY	1
Chae, SJ	1
Hwang, K	1
Kim, JJ	1
Lee, GH	1
Kim, JM	1
Hallek, M	1
Shanafelt, TD	1
Eichhorst, B	1
Yin, S	1
Gambe, RG	1
Sun, J	1
Martinez, AZ	1
Cartun, ZJ	1
Regis, FFD	1
Wan, Y	1
Fan, J	1
Brooks, AN	1
Herman, SEM	1
Ten Hacken, E	1
Taylor-Weiner, A	1
Rassenti, LZ	1
Ghia, EM	1
Kipps, TJ	1
Obeng, EA	1
Cibulskis, CL	1
Neuberg, D	1
Campagna, DR	1
Fleming, MD	1
Ebert, BL	1
Wiestner, A	1
Leshchiner, I	1
DeCaprio, JA	1
Getz, G	1
Reed, R	1
Carrasco, RD	1
Wu, CJ	2
Wang, L	6
Chao, XL	1
Wang, LL	1
Liu, R	1
Li, Y	1
Zhou, XJ	1
Alkhateeb, A	1
Karasneh, J	1
Abbadi, H	1
Hassan, A	1
Thornhill, M	1
Khlifi, R	1
Kallel, I	1
Hammami, B	1
Hamza-Chaffai, A	1
Rebai, A	1
Corbi, SC	1
Finoti, LS	2
Anovazzi, G	1
Tanaka, MH	1
Kim, YJ	1
Secolin, R	2
Marcaccini, AM	1
Gerlach, RF	1
Orrico, SR	1
Cirelli, JA	1
Scarel-Caminaga, RM	3
Emingil, G	2
Han, B	1
Gürkan, A	1
Berdeli, A	2
Tervahartiala, T	2
Salo, T	1
Pussinen, PJ	1
Köse, T	1
Atilla, G	2
Sorsa, T	2
Xue, F	1
Rabie, AB	1
Luo, G	1
de Souza, TR	1
de Albuquerque Tavares Carvalho, A	1
Duarte, ÂP	1
Porter, SR	1
Leão, JC	1
Gueiros, LA	1
Niu, Y	1
Yuan, H	3
Shen, M	1
Li, H	2
Hu, Y	2
Chen, N	1
Han, Y	2
Zhou, L	1
Ma, L	2
Li, D	2
Xu, M	2
Ma, J	3
Zhang, W	3
Jiang, H	2
Wu, Y	1
Pan, Y	4
Alves-Ferreira, M	1
Pinho, T	1
Sousa, A	1
Sequeiros, J	1
Lemos, C	1
Alonso, I	1
Wang, Z	2
Yang, Y	2
Xu, JR	1
Liu, XM	1
Zhou, J	1
Yang, B	1
Li, M	1
Wang, YJ	1
Xia, WF	1
Ma, XP	1
Li, XR	1
Dong, H	1
Yi, JL	1
Ding, C	2
Ji, X	1
Chen, X	2
Xu, Y	1
Zhong, L	2
Hazzaa, HH	1
Rashwan, WA	1
Attia, EA	1
Mi, N	1
Hao, Y	1
Jiao, X	1
Zheng, X	1
Song, T	1
Shi, J	1
Dong, C	1
Yakhine-Diop, SM	1
Bravo-San Pedro, JM	1
Gómez-Sánchez, R	1
Pizarro-Estrella, E	1
Rodríguez-Arribas, M	1
Climent, V	1
Aiastui, A	1
López de Munain, A	1
Fuentes, JM	1
González-Polo, RA	1
Shih, YS	1
Fu, E	1
Fu, MM	1
Lin, FG	1
Chiu, HC	1
Shen, EC	1
Chiang, CY	1
Huang, J	1
Li, C	1
Li, Z	1
Zeng, X	1
Guo, Z	1
Gao, P	1
Zhao, H	1
You, J	1
Jing, F	1
Su, S	1
Chien, M	1
Lin, C	1
Chen, M	1
Yang, S	1
Mijiti, A	1
Ling, W	1
Moming, A	1
Shimizu, M	1
Furusyo, N	1
Ikezaki, H	1
Ogawa, E	1
Hayashi, T	1
Ihara, T	1
Harada, Y	1
Toyoda, K	1
Murata, M	1
Hayashi, J	1
Treon, SP	1
Byrd, JC	1
Long, M	1
Dietrich, MF	1
Collins, RH	1
Gerber, DE	1
Kommajosyula, SP	1
Randall, ME	1
Faingold, CL	1
Gok, K	1
Cemeroglu, O	1
Cakirbay, H	1
Gunduz, E	1
Acar, M	1
Cetin, EN	1
Gunduz, M	1
Demircan, K	1
Wei, Z	1
He, JW	1
Fu, WZ	1
Zhang, ZL	1
Nao, N	1
Yamagishi, J	1
Miyamoto, H	1
Igarashi, M	1
Manzoor, R	1
Ohnuma, A	1
Tsuda, Y	1
Furuyama, W	1
Shigeno, A	1
Kajihara, M	1
Kishida, N	1
Yoshida, R	1
Takada, A	1
Reichert, S	1
Machulla, HK	1
Klapproth, J	1
Zimmermann, U	1
Reichert, Y	1
Gläser, C	1
Schaller, HG	1
Schulz, S	1
Shieh, TM	1
Tu, HF	1
Ku, TH	1
Chang, SS	1
Chang, KW	3
Liu, CJ	3
Houshmand, B	2
Rafiei, A	2
Hajilooi, M	2
Mani-Kashani, K	1
Gholami, L	1
Underwood, MR	1
Ross, LL	1
Irlbeck, DM	1
Gerondelis, P	1
Rouse, E	1
St Clair, MH	1
Trinh, L	1
Parkin, N	1
Lanier, E	1
Losonczi, E	1
Bencsik, K	1
Nagy, ZF	1
Honti, V	1
Szalczer, E	1
Rajda, C	1
Illés, Z	1
Mátyás, K	1
Rózsa, C	1
Csépány, T	1
Füvesi, J	1
Vécsei, L	1
Pirhan, D	1
Yan, L	1
Yanan, D	1
Donglan, S	1
Na, W	1
Rongmiao, Z	1
Zhifeng, C	1
Paranaíba, LM	1
Bufalino, A	1
Martelli-Júnior, H	1
de Barros, LM	1
Graner, E	1
Coletta, RD	1
Nikopensius, T	1
Birnbaum, S	1
Ludwig, KU	1
Jagomägi, T	1
Saag, M	1
Herms, S	1
Knapp, M	2
Hoffmann, P	1
Nöthen, MM	2
Metspalu, A	1
Mangold, E	1
Jang, JY	1
Park, EK	1
Ryoo, HM	1
Shin, HI	1
Kim, TH	1
Jang, JS	1
Park, HS	1
Choi, JY	1
Kwon, TG	1
Kimkong, I	1
Hirankarn, N	1
Nakkuntod, J	1
Kitkumthorn, N	2
Kelly, L	1
Fukushima, H	1
Karchin, R	1
Gow, JM	1
Chinn, LW	1
Pieper, U	1
Segal, MR	1
Kroetz, DL	1
Sali, A	1
Fan, WH	1
Liu, DL	1
Xiao, LM	1
Xie, CJ	1
Sun, SY	1
Zhang, JC	1
Wang, Y	3
Zhang, H	1
Wang, M	1
Zhang, Z	1
Song, Y	1
Zhang, S	1
Yao, T	1
Yang, L	1
Li, PQ	1
Wu, H	1
Xie, HB	1
Shen, X	1
Xie, XD	1
Sahingur, SE	1
Xia, XJ	1
Gunsolley, J	1
Schenkein, HA	1
Genco, RJ	1
De Nardin, E	1
Deng, H	1
Liu, F	1
Jin, X	1
Wang, H	2
Cao, J	1
Plantinga, TS	1
Crisan, TO	1
Oosting, M	1
van de Veerdonk, FL	1
de Jong, DJ	1
Philpott, DJ	1
van der Meer, JW	1
Girardin, SE	1
Joosten, LA	1
Netea, MG	1
Sun, X	1
Meng, H	1
Shi, D	2
Xu, L	2
Zhang, L	3
Chen, Z	1
Feng, X	1
Lu, R	1
Yang, CM	1
Hou, YY	1
Chiu, YT	1
Chen, HC	1
Chu, ST	1
Chi, CC	1
Hsiao, M	1
Lee, CY	1
Hsieh, CJ	1
Lin, YC	1
Hsieh, YD	1
Ger, LP	1
Zhu, XL	1
Meng, HX	1
Chen, ZB	1
Feng, XH	1
Zhang, X	2
Liu, CM	1
Yeh, CJ	1
Yu, CC	1
Chou, MY	1
Lin, CH	1
Wei, LH	1
Lin, CW	1
Yang, SF	1
Chien, MH	1
Gu, W	1
Liu, J	1
Niu, Q	1
Lou, Y	1
Liu, K	1
Zhang, J	1
Wen, S	1
Plaisier, E	1
Lescure, FX	1
Ronco, P	1
Xu, J	1
Liu, X	1
Yang, M	1
Sun, T	1
Zhou, Y	1
Liu, L	1
Tang, X	1
Zhou, M	1
Kuang, P	1
Tan, W	1
Yuan, Q	1
Yu, D	1
Pigossi, SC	1
Alvim-Pereira, F	1
Montes, CC	1
Trevilatto, PC	2
Menezes-Silva, R	1
Khaliq, S	1
Deeley, K	1
Letra, A	1
Vieira, AR	1
Bollée, G	1
Harambat, J	1
Bensman, A	1
Knebelmann, B	1
Daudon, M	1
Ceballos-Picot, I	1
Nishijima, T	1
Komatsu, H	1
Higasa, K	1
Takano, M	1
Tsuchiya, K	1
Hayashida, T	1
Oka, S	1
Gatanaga, H	1
e Silva, MR	1
Moreira, PR	2
da Costa, GC	1
Saraiva, AM	1
de Souza, PE	1
Amormino, SA	1
da Costa, JE	1
Gollob, KJ	1
Dutra, WO	2
Yanatatsaneejit, P	1
Boonsuwan, T	1
Mutirangura, A	1
Hsieh, YY	3
Chang, CC	3
Tsai, FJ	3
Tsai, HD	1
Yeh, LS	3
Lin, CC	3
Tsai, CH	2
Busse, WW	1
Rosenwasser, LJ	1
Noble, JA	1
White, AM	1
Lazzeroni, LC	1
Valdes, AM	1
Mirel, DB	1
Reynolds, R	1
Grupe, A	1
Aud, D	1
Peltz, G	1
Erlich, HA	1
Fassmann, A	1
Holla, LI	1
Buckova, D	1
Vasku, A	1
Znojil, V	1
Vanek, J	1
Klerk, M	1
Lievers, KJ	1
Kluijtmans, LA	1
Blom, HJ	1
den Heijer, M	1
Schouten, EG	1
Kok, FJ	1
Verhoef, P	1
Latsi, P	1
Pantelidis, P	1
Vassilakis, D	1
Sato, H	1
Welsh, KI	1
du Bois, RM	1
Chevillard, C	1
Moukoko, CE	1
Elwali, NE	1
Bream, JH	1
Kouriba, B	1
Argiro, L	1
Rahoud, S	1
Mergani, A	1
Henri, S	1
Gaudart, J	1
Mohamed-Ali, Q	1
Young, HA	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
A Phase III, Randomized, Open-label, Multicenter Study of the Safety and Efficacy of Efavirenz Versus Tenofovir When Administered in Combination With the Abacavir/Lamivudine Fixed-dose Combination Tablet as a Once-daily Regimen in Antiretroviral-naive HIV[NCT00053638]	Phase 3	345 participants	Interventional	2003-02-28	Completed
A Serological Evaluation of 77A/G and 11A/12A Associated Gene Polymorphisms of MMP-13 in Periodontitis Affected and Healthy Individuals[NCT02423304]		100 participants (Anticipated)	Observational	2015-05-31	Not yet recruiting
The Evaluation of MCP-1 and CCR-2 Gene Polymorphisms Frequency and The Effects of This Polymorphism on Gene Expression in Patients With Aggressive Periodontitis[NCT02817568]		215 participants (Actual)	Observational	2011-03-31	Completed
Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery: a Randomized, Placebo Controlled Trial[NCT02734238]	Phase 4	53 participants (Actual)	Interventional	2016-04-30	Completed
The Finnish Diabetes Prevention Study: A Follow-up Study on the Effect of a Dietary and Exercise Intervention in the Prevention of Diabetes and Its Vascular Complications[NCT00518167]		522 participants (Actual)	Interventional	1993-11-30	Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Height was measured using a stadiometer. Weight was measured using a calibrated digital scale. Body composition was determined using dual-energy X-ray absorptiometry. These data were used to calculate fat-free body mass, fat mass, and total body tissue mass. (NCT02734238)
Timeframe: end of each study phase: Day 11 for Phase 1, Day 39 for Phase 2, up to Day 85 for Phase 3

Intervention	kilograms (Least Squares Mean)
	Total Body Mass at end of Phase 1	Total Body Mass at end of Phase 2	Total Body Mass at end of Phase 3	Fat-free Mass at end of Phase 1	Fat-free Mass at end of Phase 2	Fat-free Mass at end of Phase 3	Fat Mass at end of Phase 1	Fat Mass at end of Phase 2	Fat Mass at end of Phase 3
Energy Deficit	78.3	73.3	76.5	58.3	58.0	60.5	16.8	12.2	12.8
Energy Deficit + Testosterone	78.0	75.8	79.3	57.9	60.4	63.1	16.8	12.0	12.8

Article	Year
Association between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies. World journal of surgical oncology, 2017, Aug-02, Volume: 15, Issue:1 Topics: Adenine; Asian People; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans;	2017
Chronic lymphocytic leukaemia. Lancet (London, England), 2018, 04-14, Volume: 391, Issue:10129 Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Di	2018
TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies. Journal of clinical periodontology, 2014, Volume: 41, Issue:8 Topics: Adenine; Cytosine; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Periodontitis; Poly	2014
Quantitative assessment of the associations between interleukin-8 polymorphisms and periodontitis susceptibility. Journal of periodontology, 2015, Volume: 86, Issue:2 Topics: Adenine; Asian People; Brazil; Cytosine; Ethnicity; Genetic Predisposition to Disease; Humans; Inter	2015
Is a polymorphism in 10q25 associated with non-syndromic cleft lip with or without cleft palate? A meta-analysis based on limited evidence. The British journal of oral & maxillofacial surgery, 2015, Volume: 53, Issue:1 Topics: Adenine; Chromosomes, Human, Pair 10; Cleft Lip; Cleft Palate; Genetic Predisposition to Disease; Ge	2015
Association between interleukin-8 -251A/T polymorphism and risk of lung cancer: a meta-analysis. Cancer investigation, 2014, Volume: 32, Issue:10 Topics: Adenine; Asian People; Computational Biology; Databases, Bibliographic; Genetic Association Studies;	2014
BsmI, TaqI, ApaI, and FokI polymorphisms in the vitamin D receptor gene and periodontitis: a meta-analysis of 15 studies including 1338 cases and 1302 controls. Journal of clinical periodontology, 2011, Volume: 38, Issue:3 Topics: Adenine; Aggressive Periodontitis; Alleles; Chronic Periodontitis; Deoxyribonucleases, Type II Site-	2011
A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis. PloS one, 2011, Volume: 6, Issue:12 Topics: Adenine; Angiotensinogen; China; Ethnicity; Genetic Predisposition to Disease; Guanine; Humans; Hype	2011
[Kidney and HIV infection]. Presse medicale (Paris, France : 1983), 2012, Volume: 41, Issue:3 Pt 1 Topics: Adenine; AIDS-Associated Nephropathy; Anti-HIV Agents; Biopsy; Black People; ErbB Receptors; Female;	2012
Adenine phosphoribosyltransferase deficiency. Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:9 Topics: Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Animals; Biomarkers; Disease Progression; E	2012
Mechanisms of asthma. The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:3 Suppl Topics: Adenine; Adult; Albuterol; Asthma; Bronchodilator Agents; Chemokines; Child; Cytokines; Disease Prog	2003
Analysis of association between maternal tumor necrosis factor-alpha promoter polymorphism (-308), tumor necrosis factor concentration, and preterm birth. American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:5 Topics: Adenine; Amniotic Fluid; Female; Genetic Predisposition to Disease; Guanine; Humans; Osmolar Concent	2006

Article	Year
Factors Associated with Mutations: Their Matching Rates to Cardiovascular and Neurological Diseases. International journal of molecular sciences, 2021, May-11, Volume: 22, Issue:10 Topics: Adenine; Cardiovascular Diseases; Genetic Predisposition to Disease; Humans; Mutation; Nervous Syste	2021
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation. Hepatology (Baltimore, Md.), 2017, Volume: 66, Issue:4 Topics: Adenine; Animals; Caloric Restriction; Dietary Sucrose; Fatty Liver; Genetic Predisposition to Disea	2017
Androgen receptor cytosine, adenine, and guanine trinucleotide repeat polymorphism in Korean patients with endometriosis: A case-control study. European journal of obstetrics, gynecology, and reproductive biology, 2017, Volume: 218 Topics: Adenine; Alleles; Case-Control Studies; Chi-Square Distribution; Cytosine; Endometriosis; Female; Ge	2017
A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. Cancer cell, 2019, 02-11, Volume: 35, Issue:2 Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Alternative Splicing; Animals; Antineoplastic Agents;	2019
Association between CA repeat polymorphism in IGF1 gene promoter and colorectal cancer risk in a native Chinese population. Neoplasma, 2019, Volume: 66, Issue:6 Topics: Adenine; Case-Control Studies; China; Colorectal Neoplasms; Cytosine; Female; Genetic Predisposition	2019
Association of cell adhesion molecule gene polymorphisms with recurrent aphthous stomatitis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:10 Topics: Adenine; Adult; Alleles; Cell Adhesion Molecules; Cohort Studies; Cytosine; E-Selectin; Female; Gene	2013
DNA repair gene polymorphisms and risk of head and neck cancer in the Tunisian population. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:3 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Arginine; Case-Control Studie	2014
Clinical outcomes of periodontal therapy are not influenced by the ATC/TTC haplotype in the IL8 gene. Journal of periodontal research, 2014, Volume: 49, Issue:4 Topics: Adenine; Adult; Chronic Periodontitis; Cytosine; Dental Plaque Index; Female; Follow-Up Studies; Gen	2014
Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in generalized aggressive periodontitis: gingival crevicular fluid MMP-8 and TIMP-1 levels and outcome of periodontal therapy. Journal of periodontology, 2014, Volume: 85, Issue:8 Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Alveolar Bone Loss; Biomarkers; Cytosine; Fema	2014
Analysis of the association of COL2A1 and IGF-1 with mandibular prognathism in a Chinese population. Orthodontics & craniofacial research, 2014, Volume: 17, Issue:3 Topics: Adenine; Adolescent; Case-Control Studies; China; Collagen Type II; Female; Gene Frequency; Genetic	2014
Th1 and Th2 polymorphisms in Sjögren's syndrome and rheumatoid arthritis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:6 Topics: Adenine; Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantigens; Case-Control Stu	2014
Association between cyclooxygenase-2 gene polymorphisms and head and neck squamous cell carcinoma risk. The Journal of craniofacial surgery, 2014, Volume: 25, Issue:2 Topics: 3' Untranslated Regions; Adenine; Adult; Aged; Alcohol Drinking; Carcinoma, Squamous Cell; Case-Cont	2014
The axis inhibition protein 2 polymorphisms and non-syndromic orofacial clefts susceptibility in a Chinese Han population. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:7 Topics: Adenine; Axin Protein; Case-Control Studies; China; Chromosome Mapping; Cleft Lip; Cleft Palate; Eth	2014
Identification of genetic risk factors for maxillary lateral incisor agenesis. Journal of dental research, 2014, Volume: 93, Issue:5 Topics: Adenine; Anodontia; Axin Protein; Case-Control Studies; Cytosine; Ectodysplasins; Female; Fibroblast	2014
A miRNA-binding-site SNP of MSX1 is Associated with NSOC Susceptibility. Journal of dental research, 2014, Volume: 93, Issue:6 Topics: 3' Untranslated Regions; 5' Flanking Region; Adenine; Case-Control Studies; Cleft Lip; Cleft Palate;	2014
Polymorphisms of +2836 G>A in the apoE gene are strongly associated with the susceptibility to essential hypertension in the Chinese Hui population. Genetics and molecular research : GMR, 2014, Feb-27, Volume: 13, Issue:1 Topics: Adenine; Apolipoproteins E; Asian People; Essential Hypertension; Gene Frequency; Genetic Associatio	2014
Association study of c.910A>G and c.1686C>G polymorphisms in XRCC1 gene with risk of hepatocellular carcinoma in the Chinese population. Genetics and molecular research : GMR, 2014, Feb-28, Volume: 13, Issue:1 Topics: Adenine; Aged; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; Cytosine; DNA-Binding	2014
IL-18 gene polymorphisms in aphthous stomatitis vs. Behçet's disease in a cohort of Egyptian patients. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:10 Topics: Adenine; Adolescent; Adult; Behcet Syndrome; Case-Control Studies; Cohort Studies; Cytosine; Egypt;	2014
Association study of single nucleotide polymorphisms of MAFB with non-syndromic cleft lip with or without cleft palate in a population in Heilongjiang Province, northern China. The British journal of oral & maxillofacial surgery, 2014, Volume: 52, Issue:8 Topics: Adenine; Case-Control Studies; Child; Child, Preschool; China; Cleft Lip; Cleft Palate; Cytosine; Et	2014
G2019S LRRK2 mutant fibroblasts from Parkinson's disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy. Toxicology, 2014, Oct-03, Volume: 324 Topics: 1-Methyl-4-phenylpyridinium; Adenine; Autophagy; Case-Control Studies; Caspases; Cells, Cultured; Do	2014
Association of CCL5 and CCR5 gene polymorphisms with periodontitis in Taiwanese. Journal of periodontology, 2014, Volume: 85, Issue:11 Topics: Adenine; Adult; Aged; Aggressive Periodontitis; Base Pairing; Case-Control Studies; Chemokine CCL5;	2014
RAGE gene polymorphism and environmental factor in the risk of oral cancer. Journal of dental research, 2015, Volume: 94, Issue:3 Topics: Adenine; Areca; Base Pairing; Base Sequence; Carcinogenesis; Case-Control Studies; Cytosine; Female;	2015
Association of single-nucleotide polymorphisms in the IRF6 gene with non-syndromic cleft lip with or without cleft palate in the Xinjiang Uyghur population. The British journal of oral & maxillofacial surgery, 2015, Volume: 53, Issue:3 Topics: 5' Flanking Region; 5' Untranslated Regions; Adenine; Case-Control Studies; Cleft Lip; Cleft Palate;	2015
Predictors of kidney tubular dysfunction induced by adefovir treatment for chronic hepatitis B. World journal of gastroenterology, 2015, Feb-21, Volume: 21, Issue:7 Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Chi-Square Distribution; Fem	2015
How I treat Waldenström macroglobulinemia. Blood, 2015, Aug-06, Volume: 126, Issue:6 Topics: Adenine; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy P	2015
IGHV and Interphase Cytogenetics in a Patient With Chronic Lymphocytic Leukemia. JAMA oncology, 2015, Volume: 1, Issue:5 Topics: Adenine; Aged; Antineoplastic Agents; Biomarkers, Tumor; Cytogenetic Analysis; DNA Mutational Analys	2015
Next-Generation Sequencing for the Identification of Targetable Molecular Alterations in Cancer. JAMA oncology, 2016, Volume: 2, Issue:1 Topics: Adenine; Antineoplastic Agents; Biomarkers, Tumor; CARD Signaling Adaptor Proteins; DNA Mutational A	2016
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats. Epilepsy research, 2016, Volume: 119 Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme In	2016
Relationship between cytosine-adenine repeat polymorphism of ADAMTS9 gene and clinical and radiologic severity of knee osteoarthritis. International journal of rheumatic diseases, 2018, Volume: 21, Issue:4 Topics: ADAMTS9 Protein; Adenine; Adult; Aged; Case-Control Studies; Chi-Square Distribution; Cytosine; Dise	2018
Osteomalacia induced by long-term low-dose adefovir dipivoxil: Clinical characteristics and genetic predictors. Bone, 2016, Volume: 93 Topics: Adenine; Amino Acid Sequence; Case-Control Studies; DNA Mutational Analysis; Dose-Response Relations	2016
Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin. mBio, 2017, 02-14, Volume: 8, Issue:1 Topics: Adenine; Animals; Chickens; Genetic Predisposition to Disease; Guanine; Hemagglutinin Glycoproteins,	2017
Interferon-gamma and interleukin-12 gene polymorphisms and their relation to aggressive and chronic periodontitis and key periodontal pathogens. Journal of periodontology, 2008, Volume: 79, Issue:8 Topics: Adenine; Adult; Age Factors; Aggregatibacter actinomycetemcomitans; Alleles; Bacteria; Cytosine; Fem	2008
Association between lysyl oxidase polymorphisms and oral submucous fibrosis in older male areca chewers. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2009, Volume: 38, Issue:1 Topics: Adenine; Age Factors; Alleles; Amino Acid Sequence; Areca; Arginine; Genetic Predisposition to Disea	2009
E-selectin and L-selectin polymorphisms in patients with periodontitis. Journal of periodontal research, 2009, Volume: 44, Issue:1 Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Alleles; Arginine; Chronic Periodontitis; Cyto	2009
Sensitivity of phenotypic susceptibility analyses for nonthymidine nucleoside analogues conferred by K65R or M184V in mixtures with wild-type HIV-1. The Journal of infectious diseases, 2009, Jan-01, Volume: 199, Issue:1 Topics: Adenine; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Genetic Predisp	2009
Tumour necrosis factor alpha gene (TNF-alpha) -376 polymorphism in Hungarian patients with primary progressive multiple sclerosis. Journal of neuroimmunology, 2009, Mar-31, Volume: 208, Issue:1-2 Topics: Adenine; Adult; Female; Gene Frequency; Genetic Predisposition to Disease; Guanine; Humans; Hungary;	2009
MMP-13 promoter polymorphisms in patients with chronic periodontitis: effects on GCF MMP-13 levels and outcome of periodontal therapy. Journal of clinical periodontology, 2009, Volume: 36, Issue:6 Topics: Adenine; Adult; Aged; Alveolar Bone Loss; Chronic Periodontitis; Dental Scaling; DNA; Female; Follow	2009
Polymorphisms of XRCC1 gene and risk of gastric cardiac adenocarcinoma. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2009, Volume: 22, Issue:5 Topics: Adenine; Adenocarcinoma; Adult; Aged; Arginine; Cardia; Case-Control Studies; Codon; Cytosine; DNA R	2009
Lack of association between IRF6 polymorphisms (rs2235371 and rs642961) and non-syndromic cleft lip and/or palate in a Brazilian population. Oral diseases, 2010, Volume: 16, Issue:2 Topics: Adenine; Alleles; Brazil; Case-Control Studies; Cleft Lip; Cleft Palate; Gene Frequency; Genetic Pre	2010
Susceptibility locus for non-syndromic cleft lip with or without cleft palate on chromosome 10q25 confers risk in Estonian patients. European journal of oral sciences, 2010, Volume: 118, Issue:3 Topics: Adenine; Case-Control Studies; Chromosome Mapping; Chromosomes, Human, Pair 10; Cleft Lip; Cleft Pal	2010
Polymorphisms in the Matrilin-1 gene and risk of mandibular prognathism in Koreans. Journal of dental research, 2010, Volume: 89, Issue:11 Topics: Adenine; Adult; Cartilage Oligomeric Matrix Protein; Case-Control Studies; Cytosine; Exons; Extracel	2010
Tumour necrosis factor-alpha gene polymorphisms and susceptibility to oral lichen planus. Oral diseases, 2011, Volume: 17, Issue:2 Topics: Adenine; Adult; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guani	2011
Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains. Protein science : a publication of the Protein Society, 2010, Volume: 19, Issue:11 Topics: Adenine; Amino Acid Sequence; ATP-Binding Cassette Transporters; Binding Sites; Genetic Predispositi	2010
Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population? Oral diseases, 2011, Volume: 17, Issue:3 Topics: Adenine; Adult; Aged; Alcohol Drinking; Case-Control Studies; China; Chromosome Mapping; Chronic Per	2011
Replication of two novel susceptibility loci for non-syndromic orofacial clefts in a Chinese population. Oral diseases, 2011, Volume: 17, Issue:3 Topics: Adenine; Alleles; Case-Control Studies; Child; China; Chromosome Mapping; Chromosomes, Human, Pair 1	2011
Association of CDH1 promoter polymorphism and the risk of non-syndromic orofacial clefts in a Chinese Han population. Archives of oral biology, 2011, Volume: 56, Issue:1 Topics: Adenine; Antigens, CD; Cadherins; Case-Control Studies; Child, Preschool; China; Cleft Lip; Cleft Pa	2011
Association of Wnt3A gene variants with non-syndromic cleft lip with or without cleft palate in Chinese population. Archives of oral biology, 2011, Volume: 56, Issue:1 Topics: Adenine; Alleles; Case-Control Studies; China; Cleft Lip; Cleft Palate; Female; Gene Frequency; Gene	2011
Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis. Journal of periodontal research, 2011, Volume: 46, Issue:2 Topics: Adenine; Chronic Periodontitis; Cytosine; Dental Plaque Index; Female; Gene Frequency; Genetic Predi	2011
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2. Gut, 2011, Volume: 60, Issue:9 Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adenine; Autophagy; Autophagy-Related Proteins; Carrier Proteins;	2011
Analysis of plasma calprotectin and polymorphisms of S100A8 in patients with aggressive periodontitis. Journal of periodontal research, 2011, Volume: 46, Issue:3 Topics: Adenine; Adult; Aggressive Periodontitis; Calgranulin A; Female; Gene Frequency; Genetic Predisposit	2011
Interaction between tumour necrosis factor-α gene polymorphisms and substance use on risk of betel quid-related oral and pharyngeal squamous cell carcinoma in Taiwan. Archives of oral biology, 2011, Volume: 56, Issue:10 Topics: Adenine; Adult; Aged; Alcohol Drinking; Alleles; Areca; Carcinoma, Squamous Cell; Case-Control Studi	2011
Association analysis between the -2518MCP-1(A/G) polymorphism and generalized aggressive periodontitis in a Chinese population. Journal of periodontal research, 2012, Volume: 47, Issue:3 Topics: Adenine; Adult; Aggressive Periodontitis; Case-Control Studies; Chemokine CCL2; China; Cohort Studie	2012
Impact of interleukin-8 gene polymorphisms and environmental factors on oral cancer susceptibility in Taiwan. Oral diseases, 2012, Volume: 18, Issue:3 Topics: 3' Untranslated Regions; Adenine; Areca; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies	2012
Genetic variation and significant association of polymorphism rs7700944 G>A of TIM-4 gene with rheumatoid arthritis susceptibility in Chinese Han and Hui populations. International journal of immunogenetics, 2012, Volume: 39, Issue:5 Topics: Adenine; Alleles; Arthritis, Rheumatoid; Asian People; Case-Control Studies; China; Ethnicity; Femal	2012
The functional cytotoxic T lymphocyte-associated Protein 4 49G-to-A genetic variant and risk of pancreatic cancer. Cancer, 2012, Oct-01, Volume: 118, Issue:19 Topics: Adenine; Age Factors; Aged; Alcohol Drinking; Asian People; Case-Control Studies; CTLA-4 Antigen; Di	2012
Genetic association study between Interleukin 10 gene and dental implant loss. Archives of oral biology, 2012, Volume: 57, Issue:9 Topics: Adenine; Alleles; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular	2012
Influence of cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms in periodontitis. Archives of oral biology, 2012, Volume: 57, Issue:9 Topics: Adenine; Adolescent; Adult; Aged; Aggressive Periodontitis; Alleles; Chronic Periodontitis; CTLA-4 A	2012
Genetic susceptibility to periapical disease: conditional contribution of MMP2 and MMP3 genes to the development of periapical lesions and healing response. Journal of endodontics, 2012, Volume: 38, Issue:5 Topics: Adenine; Dental Caries; Dental Pulp Necrosis; Dentin; Female; Gene Frequency; Genetic Predisposition	2012
Single nucleotide polymorphisms in ABCC2 associate with tenofovir-induced kidney tubular dysfunction in Japanese patients with HIV-1 infection: a pharmacogenetic study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Volume: 55, Issue:11 Topics: Adenine; Adult; Cohort Studies; Cross-Sectional Studies; Female; Genetic Predisposition to Disease;	2012
Association of CD28 and CTLA-4 gene polymorphisms with aggressive periodontitis in Brazilians. Oral diseases, 2013, Volume: 19, Issue:6 Topics: Adenine; Adolescent; Adult; Aged; Aggressive Periodontitis; Brazil; CD28 Antigens; Chronic Periodont	2013
XRCC1 gene polymorphisms and risk of ameloblastoma. Archives of oral biology, 2013, Volume: 58, Issue:6 Topics: Adenine; Adult; Ameloblastoma; Arginine; Codon; DNA Repair; DNA-Binding Proteins; Female; Gene Frequ	2013
Estrogen receptor thymine-adenine dinucleotide repeat polymorphism is associated with susceptibility to leiomyoma. Fertility and sterility, 2003, Volume: 79, Issue:1 Topics: Adenine; Dinucleotide Repeats; Female; Genetic Predisposition to Disease; Genotype; Humans; Leiomyom	2003
A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. Diabetes, 2003, Volume: 52, Issue:6 Topics: Adenine; California; Cytosine; Diabetes Mellitus, Type 1; DNA-Binding Proteins; Expressed Sequence T	2003
Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population. Journal of periodontal research, 2003, Volume: 38, Issue:4 Topics: Adenine; Adult; Case-Control Studies; Chronic Disease; Czech Republic; Female; Gene Frequency; Genet	2003
The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study. Thrombosis research, 2003, May-01, Volume: 110, Issue:2-3 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Case-Control Studies; Coronary D	2003
Analysis of IL-12 p40 subunit gene and IFN-gamma G5644A polymorphisms in Idiopathic Pulmonary Fibrosis. Respiratory research, 2003, Volume: 4 Topics: 3' Untranslated Regions; Adenine; Case-Control Studies; DNA Primers; Female; Gene Frequency; Genetic	2003
IFN-gamma polymorphisms (IFN-gamma +2109 and IFN-gamma +3810) are associated with severe hepatic fibrosis in human hepatic schistosomiasis (Schistosoma mansoni). Journal of immunology (Baltimore, Md. : 1950), 2003, Nov-15, Volume: 171, Issue:10 Topics: Adenine; DNA; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Interferon-gamma; Liver	2003
Association of CTLA-4 gene polymorphism with oral submucous fibrosis in Taiwan. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2004, Volume: 33, Issue:4 Topics: Adenine; Alleles; Antigens, CD; Antigens, Differentiation; Chi-Square Distribution; CTLA-4 Antigen;	2004
Androgen receptor gene cytosine, adenine, and guanine trinucleotide repeats in patients with endometriosis. Journal of the Society for Gynecologic Investigation, 2004, Volume: 11, Issue:4 Topics: Adenine; Adult; Alleles; Cytosine; Endometriosis; Female; Gene Frequency; Genetic Predisposition to	2004
Interleukin 10 gene promoter polymorphisms are associated with chronic periodontitis. Journal of clinical periodontology, 2004, Volume: 31, Issue:6 Topics: Adenine; Adult; Chronic Disease; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease	2004
Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease. Journal of clinical periodontology, 2004, Volume: 31, Issue:6 Topics: Adenine; Adult; Aged; Alleles; Chronic Disease; Female; Gene Frequency; Genetic Predisposition to Di	2004
IL-10 promoter nt -1082A/G polymorphism and human papillomavirus infection in cytologic abnormalities of the uterine cervix. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2004, Volume: 24, Issue:4 Topics: Adenine; Alleles; Cervix Uteri; Cross-Sectional Studies; Female; Follow-Up Studies; Genetic Predispo	2004
Analysis of the -1438 G/A polymorphism of the 5-HT2A serotonin receptor gene in bulimia nervosa patients with or without a history of anorexia nervosa. Psychiatric genetics, 2004, Volume: 14, Issue:2 Topics: Adenine; Adolescent; Adult; Anorexia Nervosa; Bulimia; Female; Gene Frequency; Genetic Predispositio	2004
Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins. Physiological genomics, 2004, Nov-17, Volume: 19, Issue:3 Topics: Adenine; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Autonomic Nervous System;	2004
Tumor necrosis factor-alpha-308 promoter and p53 codon 72 gene polymorphisms in women with leiomyomas. Fertility and sterility, 2004, Volume: 82 Suppl 3 Topics: Adenine; Alleles; Case-Control Studies; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 6; Cod	2004
Androgen receptor trinucleotide polymorphism in leiomyoma. Journal of assisted reproduction and genetics, 2004, Volume: 21, Issue:12 Topics: Adenine; Alleles; Cytosine; DNA; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype	2004
The extent of ossification of posterior longitudinal ligament of the spine associated with nucleotide pyrophosphatase gene and leptin receptor gene polymorphisms. Spine, 2005, Apr-15, Volume: 30, Issue:8 Topics: Adenine; Case-Control Studies; Female; Gene Deletion; Genetic Predisposition to Disease; Genetic Var	2005
Tumor necrosis factor receptor gene polymorphisms in Crohn's disease: association with clinical phenotypes. The American journal of gastroenterology, 2005, Volume: 100, Issue:5 Topics: Adenine; Adult; Cohort Studies; Colitis; Crohn Disease; Female; Gene Frequency; Genetic Predispositi	2005
Association of the myeloperoxidase -468G-->A polymorphism with gastric inflammation and duodenal ulcer risk. World journal of gastroenterology, 2005, May-14, Volume: 11, Issue:18 Topics: Adenine; Adult; Aged; Duodenal Ulcer; Female; Gastritis; Genetic Predisposition to Disease; Guanine;	2005
TNF-alpha G-308A polymorphism is associated with rheumatic fever and correlates with increased TNF-alpha production. Journal of autoimmunity, 2005, Volume: 25, Issue:2 Topics: Adenine; Adolescent; Adult; Alleles; Child; DNA Mutational Analysis; Gene Frequency; Genetic Predisp	2005
Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery. The heart surgery forum, 2005, Volume: 8, Issue:3 Topics: Adenine; Aged; Alleles; Atrial Fibrillation; Blood Loss, Surgical; Coronary Artery Bypass; Coronary	2005
Tumor necrosis factor-alpha promoter polymorphism is associated with susceptibility to oral squamous cell carcinoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2005, Volume: 34, Issue:10 Topics: Adenine; Alleles; Base Sequence; Carcinoma, Squamous Cell; Case-Control Studies; Female; Gene Freque	2005
Genotype distribution of estrogen receptor-alpha, catechol-O-methyltransferase, and cytochrome P450 17 gene polymorphisms in Caucasian women with uterine leiomyomas. Fertility and sterility, 2006, Volume: 85, Issue:2 Topics: Adenine; Adult; Case-Control Studies; Catechol O-Methyltransferase; Cytosine; Estrogen Receptor alph	2006
Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population. JOP : Journal of the pancreas, 2006, May-09, Volume: 7, Issue:3 Topics: Adenine; Adult; Case-Control Studies; Cytosine; Diabetes Mellitus, Type 2; Female; Gene Frequency; G	2006
Analysis of the effect of multiple genetic variants of cardiovascular disease risk on insulin concentration variability in healthy adults of the STANISLAS cohort. The role of FGB-455 G/A polymorphism. Atherosclerosis, 2007, Volume: 191, Issue:2 Topics: Adenine; Adult; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Fasting; Female; F	2007
Maternal IVS1-401 T allele of the estrogen receptor alpha is an independent predictor of late fetal loss. Fertility and sterility, 2006, Volume: 86, Issue:2 Topics: Abortion, Spontaneous; Adenine; Alleles; Case-Control Studies; Cytosine; Estrogen Receptor alpha; Fa	2006
The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients. Arthritis research & therapy, 2006, Volume: 8, Issue:4 Topics: Adenine; Aged; Arthritis, Rheumatoid; Austria; Case-Control Studies; Female; Gene Frequency; Genetic	2006
Evaluation of oral tenofovir disoproxil fumarate and topical tenofovir GS-7340 to protect infant macaques against repeated oral challenges with virulent simian immunodeficiency virus. Journal of acquired immune deficiency syndromes (1999), 2006, Volume: 43, Issue:1 Topics: Adenine; Administration, Oral; Administration, Topical; Alanine; Animals; Anti-HIV Agents; Genetic P	2006
Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population. Journal of clinical periodontology, 2006, Volume: 33, Issue:10 Topics: Adenine; Adult; Alleles; Brazil; Chronic Disease; Female; Gene Frequency; Genetic Predisposition to	2006
The short vitamin D receptor is associated with increased risk for generalized aggressive periodontitis. Journal of clinical periodontology, 2006, Volume: 33, Issue:8 Topics: Adenine; Adult; Alveolar Bone Loss; Codon; Cytosine; Exons; Female; Gene Frequency; Genetic Predispo	2006
Prothrombin A19911G polymorphism and the risk of venous thromboembolism. Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:12 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Factor V; Female;	2006
The association of prothrombin A19911G polymorphism with plasma prothrombin activity and venous thrombosis: results of the MEGA study, a large population-based case-control study. Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:12 Topics: Adenine; Adult; Aged; Case-Control Studies; Factor V; Female; Gene Frequency; Genetic Predisposition	2006
Type and location of venous thromboembolism in patients with factor V Leiden or prothrombin G20210A and in those with no thrombophilia. Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:1 Topics: Adenine; Adolescent; Adult; Age Distribution; Age Factors; Aged; Aging; Child; Cohort Studies; Facto	2007
Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy. The Journal of infectious diseases, 2006, Dec-01, Volume: 194, Issue:11 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Case-Control Studies; Fanconi Syndrome; Female; Gene Frequenc	2006
Breast cancer risk associated with AURKA 91T -->A polymorphism in relation to BRCA mutations. Cancer letters, 2007, Jun-08, Volume: 250, Issue:2 Topics: Adenine; Alleles; Aurora Kinase A; Aurora Kinases; Case-Control Studies; Female; Genes, BRCA1; Genes	2007
Association of genetic polymorphisms of ACADSB and COMT with human hypertension. Journal of hypertension, 2007, Volume: 25, Issue:1 Topics: Acyl-CoA Dehydrogenases; Adenine; Aged; Asian People; Blood Pressure; Cohort Studies; Cytosine; DNA-	2007
Angiotensinogen promoter sequence variants in essential hypertension. American journal of hypertension, 2006, Volume: 19, Issue:12 Topics: Adenine; Angiotensinogen; Black or African American; Cohort Studies; Cytosine; Female; Gene Frequenc	2006
Association of A313 G polymorphism (GSTP1B) in the glutathione-S-transferase P1 gene with sporadic Parkinson's disease. European journal of neurology, 2007, Volume: 14, Issue:2* Topics: Adenine; Aged; Aged, 80 and over; Alleles; Cytochrome P-450 CYP2D6; Gene Deletion; Genetic Predispos	2007
Early vulnerability to ischemia/reperfusion injury in motor terminals innervating fast muscles of SOD1-G93A mice. Experimental neurology, 2007, Volume: 204, Issue:1 Topics: Adenine; Animals; Denervation; Genetic Predisposition to Disease; Guanine; Hindlimb; Humans; Male; M	2007
TNFalpha-308G/A polymorphism as a risk factor for HPV associated cervical cancer in Indian population. Cellular oncology : the official journal of the International Society for Cellular Oncology, 2007, Volume: 29, Issue:3 Topics: Adenine; Base Sequence; Case-Control Studies; DNA Mutational Analysis; Female; Genetic Predispositio	2007
Angiotensin-converting enzyme gene 2350 G/A polymorphism is associated with left ventricular hypertrophy but not essential hypertension. Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:1 Topics: Adenine; Adult; Asian People; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; G	2007
Association of CD14, IL1B, IL6, IL10 and TNFA functional gene polymorphisms with symptomatic dental abscesses. International endodontic journal, 2007, Volume: 40, Issue:7 Topics: Abscess; Adenine; Adult; Age Factors; Case-Control Studies; Chromosome Mapping; Cross-Sectional Stud	2007
MTR 2756 A > G polymorphism is associated with the risk of systemic lupus erythematosus in the Polish population. Lupus, 2007, Volume: 16, Issue:6 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Adult; Gene Frequency; Genetic P	2007
Association of the HTRA1 -625G>A promoter gene polymorphism with exudative age-related macular degeneration in a Central European population. Molecular vision, 2007, Jul-24, Volume: 13 Topics: Adenine; Aged; Aged, 80 and over; Complement Factor H; Europe; Female; Genetic Predisposition to Dis	2007
ApolipoproteinA1-75 G/A (M1-) polymorphism and lipoprotein(a); anti- vs. pro-Atherogenic properties. Lipids in health and disease, 2007, Aug-06, Volume: 6 Topics: Adenine; Apolipoprotein A-I; Atherosclerosis; Gene Frequency; Genetic Carrier Screening; Genetic Pre	2007
Diabetic retinopathy and IGF-1 gene polymorphic cytosine-adenine repeats in a Southern Indian cohort. Ophthalmic research, 2007, Volume: 39, Issue:5 Topics: Adenine; Aged; Cohort Studies; Cytosine; Diabetic Retinopathy; Female; Genetic Predisposition to Dis	2007
[Metabolic bone disease in premature infants and genetic polymorphisms]. Orvosi hetilap, 2007, Oct-14, Volume: 148, Issue:41 Topics: Adenine; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Density; Bone Diseases, Metabolic; B	2007
Association of CA repeat polymorphism in estrogen receptor beta gene with postmenopausal osteoporosis in Chinese. Journal of genetics and genomics = Yi chuan xue bao, 2007, Volume: 34, Issue:10 Topics: Adenine; Alleles; Asian People; Base Sequence; Case-Control Studies; Cytosine; Dinucleotide Repeats;	2007
Gastrointestinal tract involvement associated with the 3243A>G mitochondrial DNA mutation. Neurology, 2008, Apr-08, Volume: 70, Issue:15 Topics: Adenine; Adult; Base Sequence; DNA Mutational Analysis; DNA, Mitochondrial; Electron Transport Compl	2008
G to A polymorphism in the CACNLG gene. Human molecular genetics, 1993, Volume: 2, Issue:12 Topics: Adenine; Base Sequence; Calcium Channels; Chromosome Mapping; Chromosomes, Human, Pair 17; DNA Prime	1993
Polymorphisms in the DNA repair gene XPD: correlations with risk and age at onset of basal cell carcinoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:1 Topics: Adenine; Adult; Age Factors; Age of Onset; Alleles; Carcinoma, Basal Cell; Confidence Intervals; Cyt	1999
Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependence. American journal of medical genetics, 2001, Jan-08, Volume: 105, Issue:1 Topics: Adenine; Adult; Alcoholism; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to	2001
Psychiatric symptoms and CAG repeats in neurologically asymptomatic Huntington's disease gene carriers. Psychiatry research, 2001, Jul-24, Volume: 102, Issue:3 Topics: Adenine; Adult; Age of Onset; Cognition; Cytosine; Female; Genetic Predisposition to Disease; Guanin	2001

adenine and Genetic Predisposition

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