adenine has been researched along with Folic Acid Deficiency in 6 studies
Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with nimodipine [an L voltage-sensitive calcium channel (LVSCC) antagonist], MK-801 (an NMDA channel antagonist) and thapsigarin (an inhibitor of efflux of calcium from internal stores) indicated that folate deprivation initially induced calcium influx via the LVSCC, with subsequent additional calcium derived from NMDA channels and internal stores." | 1.32 | Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation. ( Dhivant, S; Mitton, K; Ortiz, DO; Rogers, E; Shea, TB; Tjiattas, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Y | 1 |
| Huang, G | 1 |
| Chen, S | 1 |
| Gou, Y | 1 |
| Dong, Z | 1 |
| Zhang, X | 1 |
| Tjiattas, L | 1 |
| Ortiz, DO | 1 |
| Dhivant, S | 1 |
| Mitton, K | 1 |
| Rogers, E | 1 |
| Shea, TB | 1 |
| Petering, HG | 1 |
| Delor, RA | 1 |
| Poirier, LA | 1 |
| de Waard, H | 1 |
| Hoffbrand, AV | 1 |
| Pegg, AE | 1 |
6 other studies available for adenine and Folic Acid Deficiency
| Article | Year |
|---|---|
Folic acid deficiency increases brain cell injury via autophagy enhancement after focal cerebral ischemia.
Topics: Adenine; Animals; Autophagosomes; Autophagy; Beclin-1; Biomarkers; Brain Ischemia; Cell Body; Cerebr | 2016 |
Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation.
Topics: Adenine; Aniline Compounds; Animals; Calcium; Cells, Cultured; Chick Embryo; Cytosol; Dizocilpine Ma | 2004 |
Inability of Thymine and Adenine to Substitute for Pteroylglutamic Acid in the Folic Acid-deficient Rat.
Topics: Adenine; Animals; Folic Acid; Folic Acid Deficiency; Humans; Rats; Thymine | 1949 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic | 1973 |
[Effect of thymine and adenine in nutrition on folic-acid deficient rats].
Topics: Adenine; Animals; Female; Folic Acid Deficiency; Male; Methotrexate; Rats; Thymine | 1974 |
Base composition of normal and megaloblastic bone marrow DNA.
Topics: Adenine; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Cytidine; Cytosine; DNA; Folic Acid Def | 1972 |