adenine and Experimental Neoplasms
adenine has been researched along with Experimental Neoplasms in 103 studies
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"These CLL-like cells show genome instability and dysregulation of multiple CLL-associated cellular processes, including deregulated B cell receptor signaling, which we also identified in human CLL cases." | 1.51 | A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. ( Brooks, AN; Campagna, DR; Carrasco, RD; Cartun, ZJ; Cibulskis, CL; DeCaprio, JA; Ebert, BL; Fan, J; Fleming, MD; Gambe, RG; Getz, G; Ghia, EM; Herman, SEM; Kipps, TJ; Leshchiner, I; Martinez, AZ; Neuberg, D; Obeng, EA; Rassenti, LZ; Reed, R; Regis, FFD; Sun, J; Taylor-Weiner, A; Ten Hacken, E; Wan, Y; Wang, L; Wiestner, A; Wu, CJ; Yin, S, 2019) |
" Moreover, we show that the efficacy of DSR-29133 was significantly improved when administered in combination with low-dose fractionated radiotherapy (RT)." | 1.43 | Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy. ( Adlard, AL; Cheadle, EJ; Dovedi, SJ; Eguchi, K; Hirose, Y; Honeychurch, J; Hughes, G; Illidge, TM; Jewsbury, PJ; Koga-Yamakawa, E; Murata, M; Ota, Y; Stratford, IJ; Sugaru, E; Umehara, H; Wilkinson, RW; Yamamoto, S, 2016) |
" In a preclinical model of renal cell cancer, systemic administration of DSR-6434 dosed once weekly resulted in a significant anti-tumor response." | 1.42 | TLR7 tolerance is independent of the type I IFN pathway and leads to loss of anti-tumor efficacy in mice. ( Dovedi, SJ; Harada, H; Hirose, Y; Jewsbury, PJ; Koga-Yamakawa, E; Li, CJ; Murata, M; Ota, Y; Robinson, DT; Sugaru, E; Umehara, H; Wilkinson, RW; Yamamoto, S, 2015) |
" To pursue compounds with better biopharmaceutical properties, we have developed a series of fully synthetic orally bioavailable inhibitors of Hsp90." | 1.36 | BIIB021, a synthetic Hsp90 inhibitor, has broad application against tumors with acquired multidrug resistance. ( Burrows, F; Lough, R; Lundgren, K; Neely, L; Timple, N; Yang, YC; Zhang, H, 2010) |
" Studies to investigate the antitumor effects of BIIB021 showed activity on both daily and intermittent dosing schedules, providing dose schedule flexibility for clinical studies." | 1.35 | BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90. ( Boehm, MF; Brekken, J; Burrows, FJ; Busch, DJ; Friedman, J; Hong, K; Huser, N; Kamal, A; Kasibhatla, SR; Lundgren, K; McKenzie, A; Neely, L; Powell, RE; Scannevin, R; Sensintaffar, JL; Timple, N; Yang, YC; Zhang, H, 2009) |
"Alanosine treatment results in the inhibition of cell division, DNA synthesis, RNA and protein synthesis (in this order), and a depletion of the cells of adenosine triphosphate." | 1.26 | Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate. ( Graff, JC; Plagemann, PG, 1976) |
Research
Studies (103)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 82 (79.61) | 18.7374 |
1990's | 4 (3.88) | 18.2507 |
2000's | 3 (2.91) | 29.6817 |
2010's | 11 (10.68) | 24.3611 |
2020's | 3 (2.91) | 2.80 |
Authors
Authors | Studies |
---|---|
Walunj, D | 1 |
Thankarajan, E | 1 |
Prasad, C | 1 |
Tuchinsky, H | 1 |
Baldan, S | 1 |
Sherman, MY | 1 |
Patsenker, L | 1 |
Gellerman, G | 1 |
Faust, A | 1 |
Bäumer, N | 1 |
Schlütermann, A | 1 |
Becht, M | 1 |
Greune, L | 1 |
Geyer, C | 1 |
Rüter, C | 1 |
Margeta, R | 1 |
Wittmann, L | 1 |
Dersch, P | 1 |
Lenz, G | 1 |
Berdel, WE | 1 |
Bäumer, S | 1 |
Lindsay, RS | 1 |
Whitesell, JC | 1 |
Dew, KE | 1 |
Rodriguez, E | 1 |
Sandor, AM | 1 |
Tracy, D | 1 |
Yannacone, SF | 1 |
Basta, BN | 1 |
Jacobelli, J | 1 |
Friedman, RS | 1 |
Yin, S | 1 |
Gambe, RG | 1 |
Sun, J | 1 |
Martinez, AZ | 1 |
Cartun, ZJ | 1 |
Regis, FFD | 1 |
Wan, Y | 1 |
Fan, J | 1 |
Brooks, AN | 1 |
Herman, SEM | 1 |
Ten Hacken, E | 1 |
Taylor-Weiner, A | 1 |
Rassenti, LZ | 1 |
Ghia, EM | 1 |
Kipps, TJ | 1 |
Obeng, EA | 1 |
Cibulskis, CL | 1 |
Neuberg, D | 1 |
Campagna, DR | 1 |
Fleming, MD | 1 |
Ebert, BL | 1 |
Wiestner, A | 1 |
Leshchiner, I | 1 |
DeCaprio, JA | 1 |
Getz, G | 1 |
Reed, R | 1 |
Carrasco, RD | 1 |
Wu, CJ | 1 |
Wang, L | 1 |
Gui, F | 1 |
Jiang, J | 1 |
He, Z | 1 |
Li, L | 1 |
Li, Y | 1 |
Deng, Z | 1 |
Lu, Y | 1 |
Wu, X | 1 |
Chen, G | 1 |
Su, J | 1 |
Song, S | 1 |
Zhang, YM | 1 |
Yun, CH | 1 |
Huang, X | 1 |
Weisberg, E | 1 |
Zhang, J | 1 |
Deng, X | 1 |
Sagiv-Barfi, I | 1 |
Kohrt, HE | 1 |
Czerwinski, DK | 1 |
Ng, PP | 1 |
Chang, BY | 1 |
Levy, R | 1 |
Zhao, X | 1 |
Chen-Kiang, S | 1 |
Shetty, S | 1 |
Di Liberto, M | 1 |
Bodo, J | 1 |
Durkin, L | 1 |
Eng, K | 1 |
Elemento, O | 1 |
Smith, MR | 1 |
Hsi, ED | 1 |
Koga-Yamakawa, E | 2 |
Murata, M | 2 |
Dovedi, SJ | 2 |
Wilkinson, RW | 2 |
Ota, Y | 2 |
Umehara, H | 2 |
Sugaru, E | 2 |
Hirose, Y | 2 |
Harada, H | 1 |
Jewsbury, PJ | 2 |
Yamamoto, S | 2 |
Robinson, DT | 1 |
Li, CJ | 1 |
Hua, F | 1 |
Li, K | 1 |
Yu, JJ | 1 |
Lv, XX | 1 |
Yan, J | 1 |
Zhang, XW | 1 |
Sun, W | 1 |
Lin, H | 1 |
Shang, S | 1 |
Wang, F | 1 |
Cui, B | 1 |
Mu, R | 1 |
Huang, B | 1 |
Jiang, JD | 1 |
Hu, ZW | 1 |
Adlard, AL | 1 |
Eguchi, K | 1 |
Honeychurch, J | 1 |
Cheadle, EJ | 1 |
Hughes, G | 1 |
Stratford, IJ | 1 |
Illidge, TM | 1 |
Ailawadhi, S | 1 |
Paulus, A | 1 |
Chanan-Khan, A | 1 |
Lundgren, K | 3 |
Zhang, H | 3 |
Brekken, J | 1 |
Huser, N | 1 |
Powell, RE | 1 |
Timple, N | 2 |
Busch, DJ | 1 |
Neely, L | 3 |
Sensintaffar, JL | 1 |
Yang, YC | 2 |
McKenzie, A | 1 |
Friedman, J | 1 |
Scannevin, R | 1 |
Kamal, A | 1 |
Hong, K | 1 |
Kasibhatla, SR | 1 |
Boehm, MF | 1 |
Burrows, FJ | 1 |
Lough, R | 1 |
Burrows, F | 2 |
Dakappagari, N | 1 |
Tangri, S | 1 |
Hipolito, L | 1 |
Estrellado, A | 1 |
Beljanski, V | 1 |
Knaak, C | 1 |
Smith, CD | 1 |
FJELDE, A | 2 |
WRBA, H | 1 |
GEIPEL, A | 1 |
HAREL, J | 1 |
HAREL, L | 1 |
LACOUR, F | 1 |
BOER, A | 1 |
IMBENOTTE, J | 1 |
MANDEL, P | 1 |
WINTZERITH, M | 1 |
BORKOWSKA, I | 1 |
MANDEL, L | 1 |
CLARK, JB | 1 |
GREENBAUM, AL | 1 |
MCLEAN, P | 1 |
REID, E | 1 |
KLENOW, H | 1 |
OVERGAARD-HANSEN, K | 2 |
CAMBRIA, A | 1 |
LOMBARDO, N | 1 |
GIUFFRIDA, AM | 1 |
SARTORELLI, AC | 3 |
BIEBER, AL | 1 |
CHANG, PK | 1 |
FISCHER, GA | 1 |
WOOLFREY, BF | 1 |
BRAGONIER, JR | 1 |
ROESKY, N | 1 |
CARVER, MJ | 1 |
WHITCUTT, JM | 1 |
ROTH, JS | 1 |
LEPAGE, GA | 3 |
JUNGA, IG | 1 |
RABOTTI, G | 1 |
ELLIS, DB | 1 |
HARTUNG, EW | 1 |
Kondo, Y | 1 |
Kondo, S | 1 |
Green, RD | 1 |
Margalith, M | 1 |
Manor, D | 1 |
Cohen, T | 1 |
Likhachev, AJ | 1 |
Alekandrov, VA | 1 |
Anisimov, VN | 2 |
Bespalov, VG | 1 |
Korsakov, MV | 1 |
Ovsyannikov, AI | 1 |
Popovich, IG | 1 |
Napalkov, NP | 1 |
Tomatis, L | 1 |
Buchwald, M | 1 |
Ullman, B | 1 |
Martin, DW | 2 |
Makukho, LV | 1 |
Volkolupova, OP | 1 |
Ascoli, M | 1 |
Xu, ZQ | 1 |
Qiu, YL | 1 |
Chokekijchai, S | 1 |
Mitsuya, H | 1 |
Zemlicka, J | 1 |
Braña, MF | 1 |
Castellano, JM | 1 |
Morán, M | 1 |
Pérez de Vega, MJ | 1 |
Romerdahl, CR | 1 |
Qian, XD | 1 |
Bousquet, P | 1 |
Emling, F | 1 |
Schlick, E | 1 |
Keilhauer, G | 1 |
Calvert, RJ | 1 |
Buzard, GS | 1 |
Rice, JM | 1 |
Voeks, D | 1 |
Martiniello-Wilks, R | 1 |
Madden, V | 1 |
Smith, K | 1 |
Bennetts, E | 1 |
Both, GW | 1 |
Russell, PJ | 1 |
Paik, WK | 1 |
Kim, S | 1 |
Ezirike, J | 1 |
Morris, HP | 1 |
Zylka, JM | 1 |
Plagemann, PG | 2 |
Penit, J | 1 |
Huot, J | 1 |
Jard, S | 1 |
Graff, JC | 1 |
Rapaport, E | 1 |
Zamecnik, PC | 1 |
Yuki, H | 1 |
Kawasaki, H | 1 |
Imayuki, A | 1 |
Yajima, T | 1 |
Brown, MS | 1 |
Kovanen, PT | 1 |
Goldstein, JL | 1 |
Snyder, FF | 1 |
Cruikshank, MK | 1 |
Seegmiller, JE | 1 |
Nagao, M | 1 |
Sugimura, T | 1 |
Kinniburgh, AJ | 1 |
Martin, TE | 1 |
Margison, GP | 2 |
Margison, JM | 1 |
Montesano, R | 1 |
Kolosov, AI | 1 |
Hasan, A | 1 |
Srivastava, PC | 1 |
Yip, LC | 1 |
Xu, YL | 1 |
Balis, ME | 1 |
Miko, M | 1 |
Krepelka, J | 1 |
Melka, M | 1 |
Reynolds, VL | 1 |
McGovren, JP | 1 |
Hurley, LH | 1 |
Owen, NT | 1 |
Volkman, LE | 1 |
Krueger, RG | 1 |
Boeryd, B | 1 |
Eriksson, O | 1 |
Knutson, F | 1 |
Lundin, PM | 1 |
Norrby, K | 1 |
Omori, M | 1 |
Kummer, D | 1 |
Foussard-Blanpin, O | 1 |
Giraud-Dozias, C | 1 |
Bretaudeau, J | 1 |
Narcisse, G | 1 |
Goth, R | 1 |
Rajewsky, MF | 1 |
Bishop, JM | 1 |
Summers, DF | 1 |
Levintow, L | 1 |
Gerzon, K | 1 |
Johnson, IS | 1 |
Boder, GB | 1 |
Cline, JC | 1 |
Simpson, PJ | 1 |
Speth, C | 1 |
Leonard, NJ | 1 |
Laursen, RA | 1 |
Sugiura, K | 3 |
Brown, GB | 3 |
Lamar, C | 1 |
Munger, WL | 1 |
Pitot, HC | 1 |
Tyrsted, G | 1 |
Gurd, JW | 1 |
Scholefield, PG | 1 |
Agostini, C | 1 |
Comi, P | 1 |
Mortara, G | 1 |
Shapot, VS | 1 |
Vornovitskaya, GI | 1 |
Gorozhanskaya, EG | 1 |
Davidova, SY | 1 |
Zhubanova, AA | 1 |
Krechetova, GD | 1 |
Chudinova, IA | 1 |
Nolde, S | 1 |
Hilz, H | 1 |
Siman-Tov, R | 1 |
Sachs, L | 1 |
Reddy, R | 1 |
Ro-Choi, TS | 1 |
Henning, D | 1 |
Shibata, H | 1 |
Choi, YC | 1 |
Busch, H | 1 |
McFarlane, ES | 1 |
Poirier, LA | 1 |
Nau, F | 1 |
Dybing, E | 2 |
Jeffery, WR | 1 |
Brawerman, G | 1 |
Kleihues, P | 1 |
Giraldi, T | 1 |
Steppani, G | 1 |
Baldini, L | 1 |
Holmes, DS | 1 |
Bonner, J | 1 |
Warnick, CT | 1 |
Kim, SC | 1 |
Paterson, AR | 1 |
Bowden, GT | 1 |
Boutwell, RK | 1 |
Fuska, J | 1 |
Ivanitskaya, L | 1 |
Horáková, K | 1 |
Kuhr, I | 1 |
Wheeler, GP | 2 |
Alexander, JA | 2 |
Ruiz, F | 1 |
Minguell, J | 1 |
Hill, DL | 2 |
Straight, S | 1 |
Allan, PW | 1 |
Bennett, LL | 1 |
Kaneko, T | 1 |
Teller, MN | 1 |
Parham, JC | 1 |
Kreis, W | 1 |
Dixon, GJ | 1 |
Dulmadge, EA | 1 |
Brockman, RW | 1 |
Shaddix, SC | 1 |
Frei, JV | 1 |
Kucera, LS | 1 |
Granoff, A | 1 |
Asadov, DA | 1 |
Franklin, TJ | 1 |
Cook, JM | 1 |
Cresswell, RM | 1 |
Tsunamura, S | 1 |
Clinical Trials (2)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Expanded Access to ABC-108, A Phase IIA Study of ABC294640 in the Treatment of Patients With Advanced,Unresectable Intra-hepatic, Perihilar and Extra-Hepatic Cholangiocarcinoma[NCT03414489] | 0 participants | Expanded Access | Available | ||||
A Phase I/IIA Study of ABC294640 Alone and in Combination With Hydroxychloroquine Sulfate in the Treatment of Patients With Advanced, Unresectable Intra-hepatic, Perihilar and Extra-Hepatic Cholangiocarcinoma[NCT03377179] | Phase 2 | 65 participants (Actual) | Interventional | 2018-03-07 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
4 reviews available for adenine and Experimental Neoplasms
Article | Year |
---|---|
Preclinical models of Waldenström's macroglobulinemia and drug resistance.
Topics: Adenine; Animals; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Neoplasms, Ex | 2016 |
Molecular biology of the carcinogen, 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Animals; Bacteria; Bacteriophages; Base Sequence; Carcinogens; Ce | 1976 |
The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic.
Topics: Adenine; Alkylation; Animals; Base Sequence; Binding Sites; Cell Cycle; Chemical Phenomena; Chemistr | 1986 |
Notes on some peculiarities of enzymic processes in malignant tumours and tissues of the host.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cholesterol; DNA, Neoplasm; | 1972 |
Other Studies
99 other studies available for adenine and Experimental Neoplasms
Article | Year |
---|---|
Targeted methylation facilitates DNA double strand breaks and enhances cancer suppression: A DNA intercalating/methylating dual-action chimera Amonafidazene.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Repair | 2021 |
Tumor-Cell-Specific Targeting of Ibrutinib: Introducing Electrostatic Antibody-Inhibitor Conjugates (AiCs).
Topics: Adenine; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carbocyanines; Cell Proliferation; | 2022 |
MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites.
Topics: Adenine; Animals; Antigen-Presenting Cells; Antigens; Autoimmunity; c-Mer Tyrosine Kinase; CD11 Anti | 2021 |
A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Alternative Splicing; Animals; Antineoplastic Agents; | 2019 |
A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant Btk
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Cell Proliferation; Ce | 2019 |
Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antibodies, Neoplasm; B7-H1 Antigen; Cell Cyc | 2015 |
CCMCL1: a new model of aggressive mantle cell lymphoma.
Topics: Adenine; Animals; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Proto | 2015 |
TLR7 tolerance is independent of the type I IFN pathway and leads to loss of anti-tumor efficacy in mice.
Topics: Adenine; Animals; Antigens, Neoplasm; Carcinoma, Renal Cell; Cell Line, Tumor; Clinical Protocols; C | 2015 |
TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations.
Topics: Adaptor Proteins, Signal Transducing; Adenine; Animals; Autophagy; Cell Cycle Proteins; Cell Movemen | 2015 |
Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy.
Topics: Adenine; Administration, Intravenous; Animals; Antineoplastic Agents; CD8-Positive T-Lymphocytes; Ch | 2016 |
BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90.
Topics: Adenine; Administration, Oral; Animals; Antineoplastic Agents; Benzoquinones; Blotting, Western; Cel | 2009 |
BIIB021, a synthetic Hsp90 inhibitor, has broad application against tumors with acquired multidrug resistance.
Topics: Adenine; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Be | 2010 |
An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.
Topics: Adenine; Animals; Biomarkers, Tumor; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; HSP70 Heat | 2010 |
A novel sphingosine kinase inhibitor induces autophagy in tumor cells.
Topics: Adamantane; Adenine; Animals; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Electrophoresis, | 2010 |
A novel sphingosine kinase inhibitor induces autophagy in tumor cells.
Topics: Adamantane; Adenine; Animals; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Electrophoresis, | 2010 |
A novel sphingosine kinase inhibitor induces autophagy in tumor cells.
Topics: Adamantane; Adenine; Animals; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Electrophoresis, | 2010 |
A novel sphingosine kinase inhibitor induces autophagy in tumor cells.
Topics: Adamantane; Adenine; Animals; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Electrophoresis, | 2010 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
[On the determination of the vitality of organ and tumor cultures by incorporation of marked adenine].
Topics: Adenine; Animals; Neoplasms; Neoplasms, Experimental; Tissue Culture Techniques | 1961 |
FRACTIONS WITH DIFFERING BASE COMPOSITION IN RNA FROM MALIGNANT CELLS OF MOUSE.
Topics: Adenine; Animals; Autoradiography; Base Composition; Cytosine; Electrophoresis; Guanine; Mice; Neopl | 1963 |
[ON THE EXISTENCE OF RAPIDLY LABELED DESOXYRIBONUCLEIC FRACTION IN ANIMAL CELLS].
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Neoplasm | 1964 |
CONCENTRATIONS AND RATES OF SYNTHESIS OF NICOTINAMIDE-ADENINE-DINUCLEODIDE PHOSPHATE IN PRECANCEROUS LIVERS AND HEPATOMAS INDUCED BY AZO-DYE FEEDING.
Topics: Adenine; Carcinogens; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; NADP; Neoplasms; Neoplasms, | 1964 |
EFFECT OF CORDYCEPIN TRIPHOSPHATE ON THE INCORPORATION OF (8-14C)ADENINE AND (32P)
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Chromat | 1964 |
THE INHIBITION OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE FORMATION BY CORDYCEPIN TRIPHOSPHATE IN EXTRACTS OF EHRLICH ASCITES TUMOR CELLS.
Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrli | 1964 |
[INCORPORATION OF FORMATE-C14 IN THE BASES OF THE NUCLEIC ACIDS OF STICKER'S TUMOR IN VIVO AND IN VITRO].
Topics: Adenine; Aspartic Acid; Carbon Isotopes; DNA; DNA, Neoplasm; Dogs; Formates; Glucose; Glutamine; In | 1963 |
SOME INHIBITORY PROPERTIES OF 6-N-HYDROXYLAMINOPURINE: AN ANALOG OF ADENINE AND HYPOXANTHINE.
Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Glycine; Guanine Nucleotide | 1964 |
RADIOAUTOGRAPHIC EVALUATION OF FREEZE-THAW BUFFERS USING NUCLEIC ACID- AND GLYCINE-RELATED SYNTHETIC SYSTEMS IN VITRO.
Topics: Adenine; Autoradiography; Buffers; Dextrans; Dimethyl Sulfoxide; Glycerol; Glycine; In Vitro Techniq | 1964 |
TERATOGENESIS: EFFECTS OF SUBSTITUTED PURINES AND THE INFLUENCE OF 4-HYDROXYPYRAZOLOPYRIMIDINE IN THE RAT.
Topics: Abnormalities, Drug-Induced; Adenine; Female; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Ph | 1964 |
RIBONUCLEIC ACID SYNTHESIS AND TURNOVER IN RAT LIVER AND IN A RAPIDLY GROWING TRANSPLANTABLE HEPATOMA.
Topics: Adenine; Carcinoma, Hepatocellular; Cytosine; Electrophoresis; Guanine; Histocytochemistry; Liver; L | 1964 |
METABOLISM OF PURINE NUCLEOSIDE ANALOGS.
Topics: Adenine; Animals; Antimetabolites; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasms; Neoplasms, | 1965 |
SPECIFICITY OF DNA FROM NEOPLASTIC TISSUES IN VIVO AND IN VITRO.
Topics: Adenine; Animals; Carbon Isotopes; Cytosine; DNA; DNA, Neoplasm; Formates; Guanine; Histocytochemist | 1964 |
THE EFFECT OF BETA-XYLOSYL ADENINE ON THE FORMATION OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE BY CELL-FREE EXTRACTS OF TA3 ASCITES CELLS.
Topics: Adenine; Adenosine Triphosphate; Animals; Antimetabolites; Ascites; Carbon Isotopes; Diphosphates; M | 1965 |
Stimulation of tumorous aggregations in Drosophila by addition of indoleacetic acid and adenine to culture medium.
Topics: Adenine; Animals; Culture Media; Drosophila; Indoleacetic Acids; Neoplasms; Neoplasms, Experimental | 1955 |
American Association for Cancer Research--97th annual meeting.
Topics: Adenine; Animals; Antineoplastic Agents; Benzoquinones; Glioblastoma; HSP90 Heat-Shock Proteins; Hum | 2006 |
Effects of exogenous adenosine deaminase and erythro-9-(2-hydroxy-3-nonyl) adenine on intracellular cyclic AMP levels in C1300 murine neuroblastoma in tissue culture.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cell Line; Culture Techniques; Cyclic AMP; Dipyrid | 1980 |
Cytotoxicity of arabinofuranosyladenine and erythro-9-(2-hydroxy-3-nonyl) adenine to Epstein-Barr virus producer and nonproducer lymphoma cells in culture.
Topics: Adenine; Animals; Burkitt Lymphoma; Callitrichinae; Cell Division; Cell Line; Cell Survival; Cells, | 1983 |
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea.
Topics: Adenine; Animals; Brain; DNA; Female; Fetus; Guanine; Kidney; Liver; Methylation; Methylnitrosourea; | 1983 |
Biochemical and genetic analysis of AMP deaminase deficiency in cultured mammalian cells.
Topics: Adenine; AMP Deaminase; Animals; Cell Division; Cell Line; Guanosine Triphosphate; Kinetics; Lymphom | 1981 |
[Use of an express method in studying the cytotoxic action of antitumor antibiotics].
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Carbon Radioisotopes; Cells, Cultured; Drug Evaluatio | 1981 |
Effects of hypocholesterolemia and chronic hormonal stimulation on sterol and steroid metabolism in a Leydig cell tumor.
Topics: Adenine; Animals; Cholesterol; Chorionic Gonadotropin; Dyslipidemias; Kinetics; Leydig Cell Tumor; M | 1981 |
Unsaturated acyclic analogues of 2'-deoxyadenosine and thymidine containing fluorine: synthesis and biological activity.
Topics: Adenine; Animals; Antineoplastic Agents; Antiviral Agents; Cattle; Deoxyadenosines; HIV; Humans; Hyd | 1995 |
Bis-naphthalimides: a new class of antitumor agents.
Topics: Adenine; Animals; Antineoplastic Agents; Humans; Imides; Intercalating Agents; Isoquinolines; Mice; | 1993 |
K-ras codon 12 and 61 point mutations in bromodeoxyuridine- and N-nitrosomethylurea-induced rat renal mesenchymal tumors.
Topics: Adenine; Animals; Bromodeoxyuridine; Carcinogens; Codon; Female; Genes, ras; Guanine; Kidney Neoplas | 1996 |
Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models.
Topics: Adenine; Animals; Avian Sarcoma Viruses; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; | 2002 |
S-adenosylmethionine:protein methyltransferases in hepatomas.
Topics: Adenine; Animals; Arginine; Carcinoma, Hepatocellular; Cell Nucleus; Cytosol; Histones; Liver; Liver | 1975 |
Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation.
Topics: Adenine; Animals; Biological Transport, Active; Calorimetry; Carcinoma, Hepatocellular; Cell Line; C | 1975 |
Neuroblastoma cell adenylate cyclase: direct activation by adenosine and prostaglandins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenylyl Cyclases; Cell Line; Cyclic GMP; D | 1976 |
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatoc | 1976 |
Incorporation of adenosine into ATP: formation of compartmentalized ATP.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carcinoma, Hepatocellula | 1976 |
Determination of 6-methyladenine in DNA by high-performance liquid chromatography.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cattle; Chemical Phenomena; C | 1979 |
Receptor-mediated uptake of lipoprotein-cholesterol and its utilization for steroid synthesis in the adrenal cortex.
Topics: Adenine; Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Animals; | 1979 |
A comparison of purine metabolism and nucleotide pools in normal and hypoxanthine-guanine phosphoribosyltransferase-deficient neuroblastoma cells.
Topics: Adenine; Cell Line; Hypoxanthine Phosphoribosyltransferase; Kinetics; Neoplasms, Experimental; Neuro | 1978 |
Oligo (A) oligo (A)-adjacent sequences present in nuclear ribonucleoprotein complexes and mRNA.
Topics: Adenine; Animals; Base Sequence; Cell Nucleus; Cytoplasm; Kinetics; Mice; Neoplasms, Experimental; N | 1976 |
Methylated purines in the deoxyribonucleic acid of various Syrian-golden-hamster tissues after administration of a hepatocarcinogenic dose of dimethylnitrosamine.
Topics: Adenine; Animals; Cricetinae; Dimethylnitrosamine; DNA; Guanine; Kidney; Liver; Liver Neoplasms; Lun | 1976 |
[The antiblastomatous activity of 9-methyladenine, 1-methyluracil and 1-methylthymine].
Topics: Adenine; Animals; Antimetabolites; Antineoplastic Agents; Mice; Neoplasms, Experimental; Rats; Thymi | 1975 |
Synthesis and biological studies of unsaturated acyclonucleoside analogues of S-adenosyl-L-homocysteine hydrolase inhibitors.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Anti-Bacterial Agents; Enzyme Inhibitors; Femal | 1992 |
Effects of uridine diphosphoglucose (UDPG) infusion on 5-phosphoribosyl pyrophosphate (PRPP) levels of mouse tissues.
Topics: Adenine; Animals; Cell Membrane Permeability; Glucose-6-Phosphate; Glucosephosphates; In Vitro Techn | 1987 |
Inhibition of biosynthetic processes in P388 and Ehrlich ascites cells by cloturin.
Topics: Adenine; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Leukemia | 1988 |
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone C | 1972 |
Characterization of C-type particles produced by a tissue culture-adapted murine myeloma.
Topics: Adenine; Animals; Cells, Cultured; Centrifugation, Density Gradient; Ethyl Ethers; Gammaretrovirus; | 1973 |
On the viability of tumour cells in artificially produced suspensions.
Topics: Adenine; Animals; Autoradiography; Cell Division; DNA, Neoplasm; In Vitro Techniques; Methylcholanth | 1965 |
Base composition of DNA in adenovirus-12-induced tumor.
Topics: Abdominal Neoplasms; Adenine; Adenoviridae; Animals; Brain; Chromatography, Paper; Cricetinae; Cytos | 1969 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, N | 1970 |
[Research on triacanthine: influence on wound healing and development of cancerous tumors in animal experimentation].
Topics: Adenine; Alkaloids; Allyl Compounds; Animals; Ascites; Cell Division; Neoplasms, Experimental; Plant | 1971 |
Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues.
Topics: Adenine; Alkylation; Animals; Autoradiography; Brain Chemistry; Brain Neoplasms; Carbon Radioisotope | 1974 |
Characterization of ribonuclease-resistant RNA from poliovirus-infected HeLa cells.
Topics: Adenine; Centrifugation; Cytosine; Guanine; HeLa Cells; Hot Temperature; Humans; In Vitro Techniques | 1965 |
Biological activities of 3-isoadenosine.
Topics: Adenine; Adenoviridae; Bacteria; Chromatography, Paper; Chromatography, Thin Layer; Culture Techniqu | 1966 |
Purine N-oxides. XIX. On the oncogenic N-oxide derivatives of guanine and xanthine and a nononcogenic isomer of xanthine N-oxide.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Guanine; Liver Neoplasms; Mercaptopurine; Neoplasms; Ne | 1967 |
Studies on a 32S component of nuclear RNA.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Zonal; Chromatography, Ge | 1967 |
Inhibition of the synthesis of 5-phosphoribosyl-1-pyrophosphate by 3'-deoxy-adenosine and structurally related nucleoside analogs.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Diphosphates; Glucose; Glucosyltransfer | 1968 |
The energy metabolism of Novikoff ascites hepatoma cells. I. The effects of glucose on the intracellular level of adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate | 1971 |
Action of ethionine, methionine, ATP, adenine, albumin and Ca 2+ on protein synthesis of normal and tumor cells.
Topics: Adenine; Adenosine Triphosphate; Albumins; Amino Acids; Analysis of Variance; Animals; Calcium; Carb | 1972 |
The cytostatic action of extracellular NAD in tumour-bearing mice.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cultur | 1972 |
Enzyme regulation in neuroblastoma cells. Selection of clones with low acetylcholinesterase activity and the independent control of acetylcholinesterase and choline-O-acetyltransferase.
Topics: Acetylcholine; Acetylcholinesterase; Acetyltransferases; Adenine; Adenosine Monophosphate; Animals; | 1972 |
MOdified nucleosides of nuclear and nucleolar low molecular weight ribonucleic acid.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Chromatography, Gel; Chro | 1972 |
Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours.
Topics: Adenine; Adenoviridae Infections; Animals; Cell-Free System; Chromatography, Paper; Cricetinae; Esch | 1972 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic | 1973 |
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellu | 1974 |
Cycloheximide inhibition of hypoxanthine transport cultured cells.
Topics: Adenine; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepa | 1974 |
Acinomycin D and purine transport in cultured rat hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cel | 1974 |
Characterization of the steady-state population of messenger RNA and its poly(adenylic acid) segment in mammalian cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Base Sequence; Carbon Radioisotopes; Centrifugatio | 1974 |
Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.
Topics: Adenine; Animals; Brain; Brain Neoplasms; Carcinogens; DNA; DNA Repair; Female; Guanine; Kidney; Kid | 1974 |
Effects of diazoacetyl-glycine amide on purine nucleotide and deoxyribonucleic acid synthesis in Ehrlich ascites tumor cells.
Topics: Adenine; Amides; Animals; Azo Compounds; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, | 1972 |
Preparation, molecular weight, base composition, and secondary structure of giant nuclear ribonucleic acid.
Topics: Adenine; Animals; Ascitic Fluid; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; Cyt | 1973 |
Inhibition of purine synthesis de novo in cultured L5178Y methylthioinosine.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosine Nucleotides; Guanosine Tri | 1973 |
Studies on the role of stimulated epidermal DNA synthesis in the initiation of skin tumors in mice by N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Acetone; Adenine; Animals; Autoradiography; Croton Oil; DNA; DNA Replication; Female; Guanine; Methy | 1974 |
Letter: The cytotoxic effects of a new antibiotic vermicule.
Topics: Adenine; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Carbon Radioisotopes; Carcinom | 1974 |
Metabolic activities of murine carcinoma 755 at various stages of growth.
Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Carcinoma; Cell-Free System; Chromatography, Pap | 1972 |
Metabolism of nucleic acids in the bone marrow of rats bearing tumour tissue of testicular origin.
Topics: Adenine; Androgens; Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Count; Female; Fe | 1971 |
Inhibition of guanine metabolism of mammalian tumor cells by the carbocyclic analogue of adenosine.
Topics: Adenine; Adenocarcinoma; Adenosine; Carbon Isotopes; Cells, Cultured; Chromatography, Paper; Cyclope | 1971 |
Studies on beta-D-xylofuranosyl-6-thioguanine in mice.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Chromatography; DNA, Neoplas | 1970 |
A comparison of the oncogenicities of 3-hydroxyxanthine, guanine 3-N-oxide, and some related compounds.
Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Female; Granuloma; Guanine; Injections, Subcutaneou | 1970 |
Metabolism of an antineoplastic methylhydrazine derivative in a P815 mouse neoplasm.
Topics: Adenine; Animals; Antineoplastic Agents; Benzoates; Carbon Isotopes; Cell Line; Chromatography, Pape | 1970 |
Hypoxanthine phosphoribosyltransferase and guanine metabolism of adenocarcinoma 755 cells.
Topics: Adenine; Adenocarcinoma; Buffers; Carbon Isotopes; Guanine; Hydrogen-Ion Concentration; Hypoxanthine | 1970 |
Feedback inhibition of purine biosynthesis in adenocarcinoma 755 and sarcoma 180 cells in culture.
Topics: Adenine; Adenocarcinoma; Animals; Azaserine; Carbon Isotopes; Cell Line; Feedback; Hypoxanthines; Me | 1970 |
Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea.
Topics: Adenine; Adenoma; Animals; Bone Marrow; Carbon Isotopes; DNA, Neoplasm; Guanine; Kidney; Liver; Lung | 1971 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomyci | 1968 |
[On the effect of some purine derivatives on experimental blastomogenesis].
Topics: Adenine; Animals; Mice; Neoplasms, Experimental; Purines; Urethane | 1968 |
The inhibition of nucleic acid synthesis by mycophenolic acid.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Caproates; DNA, Neoplasm; Guanine; Guanine Nucleotide | 1969 |
Effects of nitrogen mustard and cyclophosphamide upon the synthesis of DNA in vivo and in cell-free preparations.
Topics: Adenine; Animals; Carbon Isotopes; Cell-Free System; Cricetinae; Cyclophosphamide; Depression, Chemi | 1969 |
Purine N-oxides. XVI. Oncogenic derivatives of xanthine and guanine.
Topics: Adenine; Adenocarcinoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Fibroblasts; Fibros | 1965 |
Studies on the biochemical mode of action of a cytotoxic methylhydrazine derivative, N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide.
Topics: Adenine; Amines; Animals; Antineoplastic Agents; Carbon Isotopes; DNA; Formates; Guanine; Hydrazines | 1966 |