adenine has been researched along with Drug Overdose in 2 studies
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A reversible acute renal failure with no proximal tubulopathy and neuropsychiatric issues are discussed." | 1.51 | Overdose of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide in an HIV-1-infected subject with attempted suicide. ( Álvarez, H; Díaz-Cambre, H; García-González, J; Llibre, JM; Mariño, A; Valcarce, N, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Álvarez, H | 1 |
| Mariño, A | 1 |
| Valcarce, N | 1 |
| García-González, J | 1 |
| Díaz-Cambre, H | 1 |
| Llibre, JM | 1 |
| Vanichseni, S | 1 |
| Martin, M | 1 |
| Suntharasamai, P | 1 |
| Sangkum, U | 1 |
| Mock, PA | 1 |
| Gvetadze, RJ | 1 |
| Curlin, ME | 1 |
| Leethochawalit, M | 1 |
| Chiamwongpaet, S | 1 |
| Chaipung, B | 1 |
| McNicholl, JM | 1 |
| Paxton, LA | 1 |
| Kittimunkong, S | 1 |
| Choopanya, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Safety and Efficacy of Daily Tenofovir to Prevent HIV Infection Among Injection Drug Users in Bangkok, Thailand[NCT00119106] | Phase 2/Phase 3 | 2,413 participants (Actual) | Interventional | 2005-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Mean number of days that participants took study drug based on study drug diaries by study group. (NCT00119106)
Timeframe: Participants were asked about adherence at 3 month visits, up to 6.9 years.
| Intervention | days (Mean) |
|---|---|
| Tenofovir | 84 |
| Placebo | 84 |
Number of Participants with adverse clinical events in tenofovir and placebo arms (NCT00119106)
Timeframe: Up to 6.9 years
| Intervention | participants (Number) |
|---|---|
| Tenofovir | 1098 |
| Placebo | 1083 |
Plasma HIV RNA concentrations. (NCT00119106)
Timeframe: Among people who seroconverted, viral load was measured at month 1, 2, and every 4 months after HIV seroconversion
| Intervention | Copies/mL (Mean) |
|---|---|
| Tenofovir | 929829 |
| Placebo | 120061 |
"Number of Participants reporting injecting and sharing needles:~Assessed injecting and sharing at baseline and every 3 months during follow-up. We used GEE to determine if there was a significant decline in injecting and sharing." (NCT00119106)
Timeframe: Participants were asked about injecting and needle sharing behaviors at enrollment and every 3 month visit, up to 6.9 years
| Intervention | participants (Number) |
|---|---|
| Tenofovir | 58 |
| Placebo | 59 |
Measure tenofovir associated resistance mutations (ie, K65R and K70E) in amplified viral RNA specimens from HIV-positive participants in the placebo and tenofovir groups. (NCT00119106)
Timeframe: Specimens collected at the time of HIV seroconversion
| Intervention | Participants (Count of Participants) |
|---|---|
| Tenofovir | 0 |
| Placebo | 0 |
Number of participants (NCT00119106)
Timeframe: At enrolment
| Intervention | Participants (Count of Participants) |
|---|---|
| Tenofovir Group | 251 |
| Placebo Group | 271 |
Kaplan Meier survival curve. (NCT00119106)
Timeframe: From date of randomization until the date of first documented seroconversion or date of death from any cause, whichever came first, assessed for an average of 4.0 years, with a maximum duration of 6.9 years
| Intervention | Infections/ 100 person-years (Number) |
|---|---|
| Tenofovir | 17 |
| Placebo | 33 |
Number of Participants with Grade 3 or 4 Renal Laboratory Toxicities (NCT00119106)
Timeframe: Blood tested for creatinine level at enrollment and every 3 months, up to 6.9 years
| Intervention | participants (Number) |
|---|---|
| Tenofovir | 3 |
| Placebo | 3 |
1 trial available for adenine and Drug Overdose
| Article | Year |
|---|---|
High Mortality Among Non-HIV-Infected People Who Inject Drugs in Bangkok, Thailand, 2005-2012.
Topics: Accidents, Traffic; Adenine; Adult; Anti-HIV Agents; Cause of Death; Double-Blind Method; Drug Overd | 2015 |
1 other study available for adenine and Drug Overdose
| Article | Year |
|---|---|
Overdose of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide in an HIV-1-infected subject with attempted suicide.
Topics: Adenine; Alanine; Anti-HIV Agents; Cobicistat; Drug Combinations; Drug Overdose; Emtricitabine; HIV | 2019 |