adenine has been researched along with Dementias, Transmissible in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neurodegenerative diseases are characterized by the aggregation of misfolded proteins in the brain." | 2.50 | Prions: generation and spread versus neurotoxicity. ( Halliday, M; Mallucci, GR; Radford, H, 2014) |
| "Prion diseases are fatal neurodegenerative disorders that are derived from structural changes of the native PrPc." | 1.43 | Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1. ( Lee, JH; Lee, YJ; Moon, JH; Park, SY, 2016) |
| "During prion disease, an increase in misfolded prion protein (PrP) generated by prion replication leads to sustained overactivation of the branch of the unfolded protein response (UPR) that controls the initiation of protein synthesis." | 1.39 | Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice. ( Axten, JM; Barrett, DA; Fischer, PM; Halliday, M; Mallucci, GR; Molloy, C; Moreno, JA; Ortori, CA; Radford, H; Verity, N; Willis, AE, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scheper, W | 1 |
| Hoozemans, JJ | 1 |
| Moreno, JA | 1 |
| Halliday, M | 2 |
| Molloy, C | 1 |
| Radford, H | 2 |
| Verity, N | 1 |
| Axten, JM | 1 |
| Ortori, CA | 1 |
| Willis, AE | 1 |
| Fischer, PM | 1 |
| Barrett, DA | 1 |
| Mallucci, GR | 2 |
| Jones, B | 1 |
| Beaulieu-Boire, I | 1 |
| Fox, SH | 1 |
| McCarthy, A | 1 |
| McKinley, J | 1 |
| Lynch, T | 1 |
| Moon, JH | 1 |
| Lee, JH | 1 |
| Lee, YJ | 1 |
| Park, SY | 1 |
| Castelló Miralles, I | 1 |
| Del Val Antoñana, A | 1 |
| Muñoz Vicente, M | 1 |
| Moreno-Osset, E | 1 |
1 review available for adenine and Dementias, Transmissible
| Article | Year |
|---|---|
Prions: generation and spread versus neurotoxicity.
Topics: Adenine; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; eIF-2 Kinase; Humans; I | 2014 |
7 other studies available for adenine and Dementias, Transmissible
| Article | Year |
|---|---|
A new PERKspective on neurodegeneration.
Topics: Adenine; Alzheimer Disease; Animals; eIF-2 Kinase; Female; Humans; Indoles; Male; Memory Disorders; | 2013 |
Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice.
Topics: Adenine; Administration, Oral; Animals; Blood-Brain Barrier; Brain; eIF-2 Kinase; Eukaryotic Initiat | 2013 |
Neurodegenerative disease: Neurodegeneration halted with oral therapy in mice.
Topics: Adenine; Animals; Indoles; Nerve Degeneration; Prion Diseases; Unfolded Protein Response | 2013 |
New methods of preventing neurodegeneration? Lessons from prion diseases.
Topics: Adenine; Animals; Indoles; Nerve Degeneration; Prion Diseases; Unfolded Protein Response | 2014 |
Putting the downstream breaks on neurodegeneration?
Topics: Adenine; Animals; Indoles; Nerve Degeneration; Prion Diseases; Unfolded Protein Response | 2014 |
Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1.
Topics: Adenine; Androstadienes; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Cells, Cultured | 2016 |
[Adefovir in reactivation of chemotherapy-induced hepatitis B in an anti-Hbc-positive patient].
Topics: Adenine; Aged; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bleomycin; Dacarbaz | 2007 |