adenine has been researched along with Degenerative Disc Disease in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intervertebral disc degeneration (IDD) is a pathological process that is the primary cause of low back pain and is potentially mediated by compromised stress defense." | 1.48 | Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy. ( Hua, W; Kang, L; Li, S; Li, W; Liu, W; Luo, R; Song, Y; Tu, J; Wang, K; Wu, X; Yang, C; Yang, S; Yang, W; Zhang, Y, 2018) |
| "Metformin has been reported to stimulate autophagy, whereas autophagy is shown to protect against apoptosis and senescence." | 1.43 | Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo. ( Cai, N; Chen, D; Feng, Y; Pan, Z; Tang, Q; Tian, N; Wang, C; Wang, Q; Wang, X; Wu, Y; Xia, D; Xu, D; Xu, H; Yan, M; Zhang, JJ; Zhang, X; Zhou, K; Zhou, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tu, J | 1 |
| Li, W | 1 |
| Li, S | 1 |
| Liu, W | 1 |
| Zhang, Y | 1 |
| Wu, X | 1 |
| Luo, R | 1 |
| Hua, W | 1 |
| Wang, K | 1 |
| Song, Y | 1 |
| Kang, L | 1 |
| Yang, W | 1 |
| Yang, S | 1 |
| Yang, C | 1 |
| Ma, KG | 1 |
| Shao, ZW | 1 |
| Yang, SH | 1 |
| Wang, J | 1 |
| Wang, BC | 1 |
| Xiong, LM | 1 |
| Wu, Q | 1 |
| Chen, SF | 1 |
| Jiang, L | 1 |
| Jin, Y | 1 |
| Wang, H | 1 |
| Jiang, Y | 1 |
| Dong, J | 1 |
| Miyazaki, S | 1 |
| Kakutani, K | 1 |
| Yurube, T | 1 |
| Maeno, K | 1 |
| Takada, T | 1 |
| Zhang, Z | 1 |
| Kurakawa, T | 1 |
| Terashima, Y | 1 |
| Ito, M | 1 |
| Ueha, T | 1 |
| Matsushita, T | 1 |
| Kuroda, R | 1 |
| Kurosaka, M | 1 |
| Nishida, K | 1 |
| Chen, D | 1 |
| Xia, D | 1 |
| Pan, Z | 1 |
| Xu, D | 1 |
| Zhou, Y | 1 |
| Wu, Y | 1 |
| Cai, N | 1 |
| Tang, Q | 1 |
| Wang, C | 1 |
| Yan, M | 1 |
| Zhang, JJ | 1 |
| Zhou, K | 1 |
| Wang, Q | 1 |
| Feng, Y | 1 |
| Wang, X | 1 |
| Xu, H | 1 |
| Zhang, X | 1 |
| Tian, N | 1 |
5 other studies available for adenine and Degenerative Disc Disease
| Article | Year |
|---|---|
Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy.
Topics: Adenine; Adult; Aged; Apoptosis; Autophagy; Cells, Cultured; Deoxyglucose; Endoplasmic Reticulum Str | 2018 |
Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression.
Topics: Adenine; Animals; Apoptosis; Autophagy; Blotting, Western; Cells, Cultured; Chloroquine; Immunohisto | 2013 |
Glucosamine protects nucleus pulposus cells and induces autophagy via the mTOR-dependent pathway.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cadaverine; Cell Survival; Cellular Senescence; Dose-Respons | 2014 |
Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Apoptosis; Autophagy; Blotting, Wester | 2015 |
Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo.
Topics: Adenine; Adenylate Kinase; Animals; Apoptosis; Autophagy; Cellular Senescence; Enzyme Activation; Fe | 2016 |