adenine has been researched along with Deficiency, Mental in 18 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Activity of hypoxanthine-guanine and adenine phosphoribosyl transferase enzymes has been assayed in erythrocytes from 10 normal adults, 37 subjects with gout, and 21 mentally retarded children with high and normal urinary uric acid:creatinine ratios." | 3.65 | Phosphoribosyl transferase activity in normal subjects, gout patients, and children with mental retardation. ( Davison, AN; Eyre, C; Scott, JT, 1971) |
| "A sex-linked familial neurological disease consisting of cerebral palsy, mental retardation, choreoathetosis, and compulsive aggressive behavior is associated with a loss of an enzyme that participates in purine metabolism, namely, hypoxanthine-guanine phosphoribosyltransferase." | 3.64 | Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis. ( Kelley, WN; Rosenbloom, FM; Seegmiller, JE, 1967) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (94.44) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seegmiller, JE | 4 |
| Rosenbloom, FM | 2 |
| Kelley, WN | 2 |
| Micheli, V | 1 |
| Pescaglini, M | 1 |
| Rocchigiani, M | 1 |
| Sestini, S | 1 |
| Jacomelli, G | 1 |
| Hayek, G | 1 |
| Pompucci, G | 1 |
| Fraser, JH | 1 |
| Meyers, H | 1 |
| Henderson, JF | 2 |
| Brox, LW | 1 |
| McCoy, EE | 1 |
| van der Zee, SP | 3 |
| Schretlen, ED | 3 |
| Monnens, LA | 1 |
| Boyle, JA | 2 |
| Green, ML | 1 |
| Wood, MH | 1 |
| Fox, RM | 1 |
| Vincent, L | 1 |
| Reye, C | 1 |
| O'Sullivan, WJ | 1 |
| Sweetman, L | 3 |
| Nyhan, WL | 4 |
| Lommen, EJ | 2 |
| Vogels, GD | 1 |
| Trijbels, JM | 2 |
| Dancis, J | 1 |
| Cox, RP | 1 |
| Berman, PH | 1 |
| Jansen, V | 1 |
| Balis, ME | 1 |
| Raivio, KO | 1 |
| Astrin, KH | 1 |
| Schulman, JD | 1 |
| Graf, ML | 1 |
| Jacobsen, CB | 1 |
| Frost, P | 1 |
| Weinstein, GD | 1 |
| Chow, DC | 1 |
| Kawahara, FS | 1 |
| Saunders, T | 1 |
| Sorensen, LB | 1 |
| Eyre, C | 1 |
| Davison, AN | 1 |
| Scott, JT | 1 |
| Caldwell, IC | 1 |
| James, JA | 1 |
| Teberg, AJ | 1 |
| Nelson, LG | 1 |
| Watts, RW | 1 |
18 other studies available for adenine and Deficiency, Mental
| Article | Year |
|---|---|
Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Aggression; Athetosis; Azathioprine; Cerebral Palsy | 1967 |
Altered pyridine metabolism in the erythrocytes of a mentally retarded infant with partial HPRT deficiency.
Topics: Adenine; Carbon Radioisotopes; Child; Erythrocytes; Humans; Hypoxanthine; Hypoxanthine Phosphoribosy | 1994 |
Individual variation in inosine triphosphate accumulation in human erythrocytes.
Topics: Adenine; Adolescent; Adult; Child; Child, Preschool; Erythrocytes; Female; Guanine; Humans; Hypoxant | 1975 |
Megaloblastic anaemia in the Lesch-Nyhan syndrome.
Topics: Adenine; Anemia, Macrocytic; Cerebral Palsy; Child; Humans; Intellectual Disability; Male; Movement | 1968 |
Substrate stabilization: genetically-controlled reciprocal relationship between two enzymes.
Topics: Adenine; Athetosis; Diphosphates; Erythrocytes; Humans; Hypoxanthines; Intellectual Disability; Lesc | 1971 |
The Lesch-Nyhan syndrome: report of three cases.
Topics: Adenine; Adolescent; Adult; Allopurinol; Athetosis; Australia; Child; Humans; Hypoxanthines; Intelle | 1972 |
Further studies of the enzyme composition of mutant cells in X-linked uric aciduria.
Topics: Adenine; Athetosis; Erythrocytes; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine; Intellectual | 1972 |
Concentration of purine nucleotides in erythrocytes of patients with the Lesch-Nyhan syndrome before and during oral administration of adenine.
Topics: Adenine; Athetosis; Chemical Precipitation; Child; Child, Preschool; Erythrocytes; Hematocrit; Human | 1971 |
Detailed comparison of the urinary excretion of purines in a patient with the Lesch-Nyhan syndrome and a control subject.
Topics: Adenine; Adenosine; Athetosis; Child; Chromatography, Gel; Chromatography, Ion Exchange; Formamides; | 1970 |
Cell population density and phenotypic expression of tissue culture fibroblasts from heterozygotes of Lesch-Nyhan's disease (inosinate pyrophosphorylase deficiency).
Topics: Adenine; Autoradiography; Cell Line; Culture Techniques; Female; Fibroblasts; Heterozygote; Humans; | 1969 |
The influence of adenine on the clinical features and purine metabolism in the Lesch-Nyhan syndrome.
Topics: Adenine; Allopurinol; Athetosis; Bone Marrow; Carbon Isotopes; Child; Child, Preschool; Chorea; Comp | 1970 |
Lesch-Nyhan syndrome: preventive control by prenatal diagnosis.
Topics: Adenine; Amniotic Fluid; Athetosis; Autoradiography; Basal Ganglia; Carbon Isotopes; Cerebellum; Cer | 1970 |
Diagnosis of Lesch-Nyhan syndrome by direct study of skin specimens.
Topics: Adenine; Adolescent; Adult; Aged; Child; Clinical Enzyme Tests; Erythrocytes; Female; Fibroblasts; G | 1970 |
A new assay method for hypoxanthine-guanine phosphoribosyltransferase.
Topics: Adenine; Adenine Nucleotides; Athetosis; Carbon Isotopes; Chorea; Chromatography; Compulsive Behavio | 1970 |
Phosphoribosyl transferase activity in normal subjects, gout patients, and children with mental retardation.
Topics: Adenine; Adolescent; Adult; Child; Child, Preschool; Creatinine; Erythrocytes; Female; Gout; Guanine | 1971 |
Biochemical bases of accelerated purine biosynthesis de novo in human fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Athetosis; Biopsy; Carbon Isotopes; Child; Child, P | 1968 |
A new disorder of purine metabolism with behavioral manifestations.
Topics: Adenine; Allopurinol; Autistic Disorder; Carbon Isotopes; Child Behavior Disorders; Child, Preschool | 1969 |
Hyperuricaemia: some biochemical aspects.
Topics: Adenine; Carbon Isotopes; Glycine; Humans; In Vitro Techniques; Intellectual Disability; Metabolic D | 1969 |