adenine has been researched along with Coronary Disease in 34 studies
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a Dutch case-control study comprising 123 cases with coronary heart disease (CHD) and 540 controls, we evaluated whether the MTR 2756A>G polymorphism was associated with plasma homocysteine, vitamin B12, folate concentrations, and CHD risk." | 7.72 | The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study. ( Blom, HJ; den Heijer, M; Klerk, M; Kluijtmans, LA; Kok, FJ; Lievers, KJ; Schouten, EG; Verhoef, P, 2003) |
| "After the same period of anoxia 50% of the total pool, comprising adenosine, inosine, hypoxanthine and uric acid in approximately equal proportions, was recovered from the coronary perfusate." | 5.27 | Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development. ( Holliss, DG; Humphrey, SM; Seelye, RN, 1984) |
| "In a Dutch case-control study comprising 123 cases with coronary heart disease (CHD) and 540 controls, we evaluated whether the MTR 2756A>G polymorphism was associated with plasma homocysteine, vitamin B12, folate concentrations, and CHD risk." | 3.72 | The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study. ( Blom, HJ; den Heijer, M; Klerk, M; Kluijtmans, LA; Kok, FJ; Lievers, KJ; Schouten, EG; Verhoef, P, 2003) |
| "Coronary heart disease (CHD) and chronic periodontitis (CP) both are multifactorial chronic diseases and related to inflammation." | 1.37 | Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population? ( Fan, WH; Liu, DL; Sun, SY; Xiao, LM; Xie, CJ; Zhang, JC, 2011) |
| "We investigated the genetic predisposition in IL-6 response to coronary revascularization and studied the association between the G-174C polymorphism, IL-6 levels, and clinical outcomes of surgery." | 1.33 | Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery. ( Barnard, J; Bittar, MN; Carey, JA; Fildes, JE; Hutchinson, IV; Pravica, V; Yonan, N, 2005) |
| "Fibrinogen levels were significantly higher in subjects with CAD (n = 38, 3." | 1.29 | Beta-fibrinogen gene-455 G/A polymorphism and fibrinogen levels. Risk factors for coronary artery disease in subjects with NIDDM. ( Carter, AM; Grant, PJ; Mansfield, MW; Stickland, MH, 1996) |
| "After the same period of anoxia 50% of the total pool, comprising adenosine, inosine, hypoxanthine and uric acid in approximately equal proportions, was recovered from the coronary perfusate." | 1.27 | Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development. ( Holliss, DG; Humphrey, SM; Seelye, RN, 1984) |
| "2." | 1.27 | Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts. ( Meghji, P; Middleton, KM; Newby, AC, 1988) |
| "Hypoxanthine levels were fivefold more in Group 1 compared with Groups 2 and 3 (p less than 0." | 1.27 | Myocardial reperfusion injury. Role of myocardial hypoxanthine and xanthine in free radical-mediated reperfusion injury. ( Abd-Elfattah, AS; Brunsting, LA; Doherty, NE; Jessen, ME; Lekven, J; Wechsler, AS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (35.29) | 18.7374 |
| 1990's | 10 (29.41) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, WH | 1 |
| Liu, DL | 1 |
| Xiao, LM | 1 |
| Xie, CJ | 1 |
| Sun, SY | 1 |
| Zhang, JC | 1 |
| Schulz, S | 1 |
| Schlitt, A | 1 |
| Lutze, A | 1 |
| Lischewski, S | 1 |
| Seifert, T | 1 |
| Dudakliewa, T | 1 |
| Gawe, R | 1 |
| Werdan, K | 1 |
| Hofmann, B | 1 |
| Gläser, C | 1 |
| Schaller, HG | 1 |
| Reichert, S | 1 |
| Brilakis, ES | 1 |
| Berger, PB | 1 |
| Ballman, KV | 1 |
| Rozen, R | 1 |
| Klerk, M | 1 |
| Lievers, KJ | 1 |
| Kluijtmans, LA | 1 |
| Blom, HJ | 1 |
| den Heijer, M | 1 |
| Schouten, EG | 1 |
| Kok, FJ | 1 |
| Verhoef, P | 1 |
| Vasků, A | 1 |
| Goldbergová, M | 1 |
| Izakovicová Hollá, L | 1 |
| Sisková, L | 1 |
| Groch, L | 1 |
| Beránek, M | 1 |
| Tschöplová, S | 1 |
| Znojil, V | 1 |
| Vácha, J | 1 |
| Kovacs, A | 1 |
| Green, F | 1 |
| Hansson, LO | 1 |
| Lundman, P | 1 |
| Samnegård, A | 1 |
| Boquist, S | 1 |
| Ericsson, CG | 1 |
| Watkins, H | 1 |
| Hamsten, A | 1 |
| Tornvall, P | 1 |
| Bittar, MN | 1 |
| Carey, JA | 1 |
| Barnard, J | 1 |
| Fildes, JE | 1 |
| Pravica, V | 1 |
| Yonan, N | 1 |
| Hutchinson, IV | 1 |
| Tamagaki, K | 1 |
| Yuan, Q | 1 |
| Ohkawa, H | 1 |
| Imazeki, I | 1 |
| Moriguchi, Y | 1 |
| Imai, N | 1 |
| Sasaki, S | 1 |
| Takeda, K | 1 |
| Fukagawa, M | 1 |
| Pasque, MK | 1 |
| Wechsler, AS | 2 |
| Humphrey, SM | 3 |
| Holliss, DG | 2 |
| Seelye, RN | 2 |
| Lubbe, WF | 1 |
| Nguyen, T | 1 |
| Edwards, MF | 1 |
| Gavin, JB | 1 |
| Glover, DK | 1 |
| Ruiz, M | 1 |
| Sansoy, V | 1 |
| Barrett, RJ | 1 |
| Beller, GA | 1 |
| Iskandrian, AS | 1 |
| Munro, E | 1 |
| Patel, M | 1 |
| Chan, P | 1 |
| Betteridge, L | 1 |
| Clunn, G | 1 |
| Gallagher, K | 1 |
| Hughes, A | 1 |
| Schachter, M | 1 |
| Wolfe, J | 1 |
| Sever, P | 1 |
| Prohaska, W | 1 |
| Mannebach, H | 1 |
| Schmidt, M | 1 |
| Gleichmann, U | 1 |
| Kleesiek, K | 1 |
| Carter, AM | 1 |
| Mansfield, MW | 1 |
| Stickland, MH | 1 |
| Grant, PJ | 1 |
| Redondo, M | 1 |
| Watzke, HH | 1 |
| Stucki, B | 1 |
| Sulzer, I | 1 |
| Biasiutti, FD | 1 |
| Binder, BR | 1 |
| Furlan, M | 1 |
| Lämmle, B | 1 |
| Wuillemin, WA | 1 |
| Gardemann, A | 1 |
| Mages, P | 1 |
| Katz, N | 1 |
| Tillmanns, H | 1 |
| Haberbosch, W | 1 |
| Stangl, K | 1 |
| Cascorbi, I | 1 |
| Laule, M | 1 |
| Klein, T | 1 |
| Stangl, V | 1 |
| Rost, S | 1 |
| Wernecke, KD | 1 |
| Felix, SB | 1 |
| Bindereif, A | 1 |
| Baumann, G | 1 |
| Roots, I | 1 |
| Nguyen, A | 1 |
| Terata, K | 1 |
| Miura, H | 1 |
| Liu, Y | 1 |
| Loberiza, F | 1 |
| Gutterman, DD | 1 |
| Folsom, AR | 1 |
| Aleksic, N | 1 |
| Ahn, C | 1 |
| Boerwinkle, E | 1 |
| Wu, KK | 1 |
| Van Wylen, DG | 2 |
| Schmit, TJ | 1 |
| Lasley, RD | 1 |
| Gingell, RL | 1 |
| Mentzer, RM | 2 |
| Dorheim, TA | 1 |
| Hoffman, A | 1 |
| van der Meer, P | 1 |
| Huizer, T | 1 |
| de Jong, JW | 2 |
| Meghji, P | 1 |
| Middleton, KM | 1 |
| Newby, AC | 1 |
| Cartner, LA | 1 |
| Abd-Elfattah, AS | 1 |
| Jessen, ME | 1 |
| Lekven, J | 1 |
| Doherty, NE | 1 |
| Brunsting, LA | 1 |
| Achterberg, PW | 1 |
| Koke, JR | 1 |
| Werchan, PM | 1 |
| Sami, H | 1 |
| Bittar, N | 1 |
| Khalfer, ESh | 1 |
| Iakusheva, IA | 1 |
| Katkova, NB | 1 |
| Loginova, LA | 1 |
| Ital'ianskaia, IuV | 1 |
| Kobayashi, I | 1 |
| Busch, EW | 1 |
| Gercken, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Periodontitis and Its Microbiological Agents as Prognostic Factors in Patients With Coronary Heart Disease[NCT01045070] | 960 participants (Actual) | Observational | 2009-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for adenine and Coronary Disease
| Article | Year |
|---|---|
Metabolic intervention to affect myocardial recovery following ischemia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Ani | 1984 |
Review and management of patients with the prothrombin G20210A polymorphism.
Topics: 3' Untranslated Regions; Adenine; Brain Ischemia; Coronary Disease; Guanine; Humans; Ischemic Attack | 2000 |
32 other studies available for adenine and Coronary Disease
| Article | Year |
|---|---|
Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population?
Topics: Adenine; Adult; Aged; Alcohol Drinking; Case-Control Studies; China; Chromosome Mapping; Chronic Per | 2011 |
The importance of genetic variants in TNFα for periodontal disease in a cohort of coronary patients.
Topics: Adenine; Aged; Alleles; Bacteria; Cohort Studies; Coronary Disease; Dental Plaque Index; Diabetes Co | 2012 |
Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid.
Topics: Adenine; Aged; Coronary Angiography; Coronary Disease; Cytosine; Female; Ferredoxin-NADP Reductase; | 2003 |
The 2756A>G variant in the gene encoding methionine synthase: its relation with plasma homocysteine levels and risk of coronary heart disease in a Dutch case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine; Case-Control Studies; Coronary D | 2003 |
A haplotype constituted of four MMP-2 promoter polymorphisms (-1575G/A, -1306C/T, -790T/G and -735C/T) is associated with coronary triple-vessel disease.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Alleles; Case-Control Studies; Coronary Disease; Cytosine; | 2004 |
A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein.
Topics: Adenine; Aged; C-Reactive Protein; Case-Control Studies; Coronary Disease; Female; Genotype; Guanine | 2005 |
Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery.
Topics: Adenine; Aged; Alleles; Atrial Fibrillation; Blood Loss, Surgical; Coronary Artery Bypass; Coronary | 2005 |
Severe hyperparathyroidism with bone abnormalities and metastatic calcification in rats with adenine-induced uraemia.
Topics: Adenine; Animals; Aortic Diseases; Blood Urea Nitrogen; Calcinosis; Calcitriol; Calcium; Chronic Kid | 2006 |
Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and the substrate free anoxic isolated rat heart: relationship to contracture development.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; C | 1984 |
Antiarrhythmic action of labetalol and its effect on adenine metabolism in the isolated rat heart.
Topics: Adenine; Adenosine Monophosphate; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Di | 1983 |
The influence of adenosine on the no-reflow phenomenon in anoxic and ischaemic hearts.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Coronary Disease; | 1982 |
Effect of N-0861, a selective adenosine A1 receptor antagonist, on pharmacologic stress imaging with adenosine.
Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Exercise Test; Hemodynami | 1995 |
New directions in pharmacologic stress imaging.
Topics: Adenine; Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Norbornanes | 1995 |
Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis.
Topics: Adenine; Cell Division; Cells, Cultured; Cholesterol; Coronary Disease; Farnesol; Humans; Isopenteny | 1994 |
Evidence against heterozygous coagulation factor V 1691 G-->A mutation with resistance to activated protein C being a risk factor for coronary artery disease and myocardial infarction.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Coronary Disease; Disease Susceptibility; Drug Resistance; | 1995 |
Beta-fibrinogen gene-455 G/A polymorphism and fibrinogen levels. Risk factors for coronary artery disease in subjects with NIDDM.
Topics: Adenine; Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Fibrinoge | 1996 |
Coagulation factors II, V, VII, and X, prothrombin gene 20210G-->A transition, and factor V Leiden in coronary artery disease: high factor V clotting activity is an independent risk factor for myocardial infarction.
Topics: Activated Protein C Resistance; Adenine; Adult; Aged; Case-Control Studies; Coronary Disease; Factor | 1999 |
The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals.
Topics: Adenine; Angiotensinogen; Apolipoprotein A-I; Apolipoproteins B; Aryldialkylphosphatase; Coronary An | 1999 |
High CA repeat numbers in intron 13 of the endothelial nitric oxide synthase gene and increased risk of coronary artery disease.
Topics: Adenine; Aged; Base Sequence; Case-Control Studies; Coronary Disease; Cytosine; DNA Primers; Female; | 2000 |
Human coronary arteriolar dilation to adrenomedullin: role of nitric oxide and K(+) channels.
Topics: Adenine; Adrenomedullin; Aged; Arterioles; Calcitonin Gene-Related Peptide; Coronary Circulation; Co | 2000 |
Beta-fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: the Atherosclerosis Risk in Communities (ARIC) Study.
Topics: Adenine; Alleles; Arteriosclerosis; Cohort Studies; Coronary Disease; Fibrinogen; Genotype; Guanine; | 2001 |
Cardiac microdialysis in isolated rat hearts: interstitial purine metabolites during ischemia.
Topics: Adenine; Animals; Coronary Disease; Dialysis; Extracellular Space; In Vitro Techniques; Myocardium; | 1992 |
Enhanced interstitial fluid adenosine attenuates myocardial stunning.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coronary Disease; Dogs; Extracellular S | 1991 |
Effects of inosine and adenine on nucleotide levels in the post-ischemic rat heart, perfused with and without pyruvate.
Topics: Adenine; Adenine Nucleotides; Animals; Coronary Disease; In Vitro Techniques; Inosine; Myocardium; N | 1990 |
Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adult; AMP Deaminase; An | 1988 |
The influence of inhibitors of the ATP degradative pathway on recovery of function and high energy phosphate after transient ischemia in the rat heart.
Topics: 5'-Nucleotidase; Acute Disease; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibit | 1986 |
Myocardial reperfusion injury. Role of myocardial hypoxanthine and xanthine in free radical-mediated reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Animals; Coronary Disease; Dogs; Female; Free Radicals; Heart; Heart V | 1988 |
Adenosine deaminase inhibition and myocardial adenosine metabolism during ischemia.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Coronary Circu | 1985 |
Changes in morphology of endocytotic vesicles in cardiac capillary endothelial cells and myocytes of rats after treatment with adenine and AMP.
Topics: Adenine; Adenosine Monophosphate; Animals; Capillaries; Coronary Disease; Coronary Vessels; Endocyto | 1985 |
[Phosphorus compounds and their metabolites in ischemic heart diseases].
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Tripho | 1974 |
[Studies of ADP-induced platelet aggregation--especially on the reproducibility and individual difference in the response].
Topics: Adenine; Adenosine Diphosphate; Adolescent; Adult; Aged; Blood Coagulation; Blood Platelets; Cerebro | 1971 |
[Degradation of purine nucleotides and carbohydrates in the KC1-arrested rabbit heart and ischemic dog heart].
Topics: Adenine; Adenine Nucleotides; Animals; Coronary Disease; Dogs; Glycogen; Heart Arrest; Hypoxanthines | 1969 |