adenine has been researched along with Complications, Pregnancy in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the Promoting Maternal and Infant Survival Everywhere (PROMISE) trial, tenofovir disoproxil fumarate (TDF) use was associated with moderate or severe adverse pregnancy/neonatal outcomes." | 9.34 | Antenatal Intracellular Concentrations of Tenofovir Diphosphate and Emtricitabine Triphosphate and Associations Between Tenofovir Diphosphate and Severe Adverse Pregnancy Outcomes: IMPAACT-PROMISE (1077BF) Trial. ( Aizire, J; Brooks, KM; Butler, K; Cababasay, M; Fenton, T; Flynn, PM; Fowler, MG; Kiser, JJ; Mirochnick, M; Siberry, GK, 2020) |
| "Tenofovir-related tubule damage characterized by Fanconi syndrome, renal insufficiency and nephrogenic diabetes insipidus has been reported in the adult HIV-infected population." | 7.73 | Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir. ( Hussain, S; Khayat, A; Rathore, MH; Tolaymat, A, 2006) |
| " Potentially, lower IFN-α and IP-10 levels as well as once-weekly intranasal dosing vs daily subcutaneous or intramuscular dosing with recombinant type I IFNs could explain the lack of pregnancy effects; however, there was an undesired impact on offspring immune function." | 5.62 | GSK2245035, a TLR7 agonist, Does Not Increase Pregnancy Loss in Cynomolgus Monkeys. ( Baker, A; Bray, M; Hillegas, AE; Maier, CC; Phadnis-Moghe, AS; Posobiec, LM; Price, MA; Stanislaus, DJ, 2021) |
| "In the Promoting Maternal and Infant Survival Everywhere (PROMISE) trial, tenofovir disoproxil fumarate (TDF) use was associated with moderate or severe adverse pregnancy/neonatal outcomes." | 5.34 | Antenatal Intracellular Concentrations of Tenofovir Diphosphate and Emtricitabine Triphosphate and Associations Between Tenofovir Diphosphate and Severe Adverse Pregnancy Outcomes: IMPAACT-PROMISE (1077BF) Trial. ( Aizire, J; Brooks, KM; Butler, K; Cababasay, M; Fenton, T; Flynn, PM; Fowler, MG; Kiser, JJ; Mirochnick, M; Siberry, GK, 2020) |
| "Emerging international guidelines for the prevention of mother-to-child transmission of HIV infection across sub-Saharan Africa call for the initiation of a triple-drug antiretroviral regimen containing tenofovir, a potentially nephrotoxic agent, in all HIV-infected pregnant women at the first antenatal clinic visit." | 3.79 | Low prevalence of renal dysfunction in HIV-infected pregnant women: implications for guidelines for the prevention of mother-to-child transmission of HIV. ( Bekker, LG; Kamkuemah, M; Kaplan, R; Myer, L, 2013) |
| "Tenofovir-related tubule damage characterized by Fanconi syndrome, renal insufficiency and nephrogenic diabetes insipidus has been reported in the adult HIV-infected population." | 3.73 | Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir. ( Hussain, S; Khayat, A; Rathore, MH; Tolaymat, A, 2006) |
| " Potentially, lower IFN-α and IP-10 levels as well as once-weekly intranasal dosing vs daily subcutaneous or intramuscular dosing with recombinant type I IFNs could explain the lack of pregnancy effects; however, there was an undesired impact on offspring immune function." | 1.62 | GSK2245035, a TLR7 agonist, Does Not Increase Pregnancy Loss in Cynomolgus Monkeys. ( Baker, A; Bray, M; Hillegas, AE; Maier, CC; Phadnis-Moghe, AS; Posobiec, LM; Price, MA; Stanislaus, DJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Aizire, J | 1 |
| Brooks, KM | 1 |
| Mirochnick, M | 1 |
| Flynn, PM | 1 |
| Butler, K | 1 |
| Kiser, JJ | 1 |
| Siberry, GK | 1 |
| Fenton, T | 1 |
| Cababasay, M | 1 |
| Fowler, MG | 1 |
| Posobiec, LM | 1 |
| Hillegas, AE | 1 |
| Baker, A | 1 |
| Phadnis-Moghe, AS | 1 |
| Maier, CC | 1 |
| Stanislaus, DJ | 1 |
| Bray, M | 1 |
| Price, MA | 1 |
| Myer, L | 1 |
| Kamkuemah, M | 1 |
| Kaplan, R | 1 |
| Bekker, LG | 1 |
| Iwanaga, R | 1 |
| Sugita, N | 1 |
| Hirano, E | 1 |
| Sasahara, J | 1 |
| Kikuchi, A | 1 |
| Tanaka, K | 1 |
| Yoshie, H | 1 |
| Hussain, S | 1 |
| Khayat, A | 1 |
| Tolaymat, A | 1 |
| Rathore, MH | 1 |
| Shambaugh, GE | 1 |
| Angulo, MC | 1 |
| Koehler, RR | 1 |
| Asteria, C | 1 |
1 trial available for adenine and Complications, Pregnancy
| Article | Year |
|---|---|
Antenatal Intracellular Concentrations of Tenofovir Diphosphate and Emtricitabine Triphosphate and Associations Between Tenofovir Diphosphate and Severe Adverse Pregnancy Outcomes: IMPAACT-PROMISE (1077BF) Trial.
Topics: Adenine; Anti-HIV Agents; Case-Control Studies; Chromatography, Liquid; Drug Combinations; Emtricita | 2020 |
6 other studies available for adenine and Complications, Pregnancy
| Article | Year |
|---|---|
GSK2245035, a TLR7 agonist, Does Not Increase Pregnancy Loss in Cynomolgus Monkeys.
Topics: Abortion, Spontaneous; Adenine; Administration, Intranasal; Animals; Asthma; Chemokine CXCL10; Disea | 2021 |
Low prevalence of renal dysfunction in HIV-infected pregnant women: implications for guidelines for the prevention of mother-to-child transmission of HIV.
Topics: Adenine; Adult; Age Factors; Anti-HIV Agents; CD4 Lymphocyte Count; Contraindications; Creatinine; F | 2013 |
FcγRIIB polymorphisms, periodontitis and preterm birth in Japanese pregnant women.
Topics: Adenine; Adult; Antibodies, Bacterial; Case-Control Studies; Cytosine; Exons; Female; Gestational Ag | 2011 |
Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir.
Topics: Adenine; Anti-HIV Agents; Child; Diabetes Insipidus, Nephrogenic; Didanosine; Drug Therapy, Combinat | 2006 |
Fetal fuels. VII. Ketone bodies inhibit synthesis of purines in fetal rat brain.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine; Animals; Brain; Carbon Radioisotopes; Cycloheximide; | 1984 |
TSH receptor gene mutations and familial gestational hyperthyroidism.
Topics: Adenine; Chorionic Gonadotropin; Codon; Female; Guanine; Humans; Hyperthyroidism; Mutation; Pregnanc | 1999 |