adenine has been researched along with Colonic Neoplasms in 27 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of COX-1 inhibition on colon cancer cells, however, remains obscured." | 1.35 | Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells. ( Cho, CH; Li, HT; Li, ZJ; Sung, JJ; Wu, WK; Wu, YC; Yu, L, 2009) |
| "In contrast, colorectal cancers with codon 12 aspartic acid substitutions accounted for most of the distant hematogenous deposits (P < 0." | 1.29 | Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type. ( Christensen, S; Finkelstein, SD; Sayegh, R; Swalsky, PA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 9 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gurkan, AC | 1 |
| Arisan, ED | 1 |
| Yerlikaya, PO | 1 |
| Ilhan, H | 1 |
| Unsal, NP | 1 |
| Yang, J | 1 |
| Xu, WW | 1 |
| Hong, P | 1 |
| Ye, F | 1 |
| Huang, XH | 1 |
| Hu, HF | 1 |
| Zhang, QH | 1 |
| Yan, X | 1 |
| Li, B | 1 |
| He, QY | 1 |
| Kim, AD | 1 |
| Kang, KA | 1 |
| Kim, HS | 2 |
| Kim, DH | 2 |
| Choi, YH | 1 |
| Lee, SJ | 1 |
| Hyun, JW | 1 |
| Wang, L | 1 |
| Zhu, YR | 1 |
| Wang, S | 1 |
| Zhao, S | 1 |
| Kowalczyk, P | 1 |
| Jaworek, J | 1 |
| Kot, M | 1 |
| Sokolowska, B | 1 |
| Bielen, A | 1 |
| Janowska, B | 1 |
| Ciesla, JM | 1 |
| Szparecki, G | 1 |
| Sados, B | 1 |
| Tudek, B | 1 |
| Wu, WK | 2 |
| Wu, YC | 2 |
| Yu, L | 2 |
| Li, ZJ | 2 |
| Sung, JJ | 2 |
| Cho, CH | 2 |
| Li, J | 2 |
| Hou, N | 2 |
| Faried, A | 2 |
| Tsutsumi, S | 2 |
| Takeuchi, T | 1 |
| Kuwano, H | 2 |
| Li, HT | 1 |
| Xiong, HY | 1 |
| Guo, XL | 1 |
| Bu, XX | 1 |
| Zhang, SS | 1 |
| Ma, NN | 1 |
| Song, JR | 1 |
| Hu, F | 1 |
| Tao, SF | 1 |
| Sun, K | 1 |
| Li, R | 1 |
| Wu, MC | 1 |
| Wei, LX | 1 |
| Nishikawa, T | 1 |
| Tsuno, NH | 1 |
| Okaji, Y | 1 |
| Shuno, Y | 1 |
| Sasaki, K | 1 |
| Hongo, K | 1 |
| Sunami, E | 1 |
| Kitayama, J | 1 |
| Takahashi, K | 1 |
| Nagawa, H | 1 |
| Kundu, S | 1 |
| Brinkmeyer, MK | 1 |
| Livingston, AL | 1 |
| David, SS | 1 |
| Nakamura, Y | 1 |
| Yogosawa, S | 1 |
| Izutani, Y | 1 |
| Watanabe, H | 1 |
| Otsuji, E | 1 |
| Sakai, T | 1 |
| Yang, SY | 1 |
| Winslet, MC | 1 |
| Kang, MY | 1 |
| Lee, BB | 1 |
| Ji, YI | 1 |
| Jung, EH | 1 |
| Chun, HK | 1 |
| Song, SY | 1 |
| Park, SE | 1 |
| Park, J | 1 |
| Sami, SM | 1 |
| Dorr, RT | 1 |
| Sólyom, AM | 1 |
| Alberts, DS | 1 |
| Remers, WA | 1 |
| Houri, JJ | 1 |
| Ogier-Denis, E | 2 |
| Trugnan, G | 1 |
| Codogno, P | 2 |
| Terunuma, H | 1 |
| Hayakashi, T | 1 |
| Tsuneyoshi, T | 1 |
| Fujita, M | 1 |
| Kino, I | 1 |
| Baba, S | 1 |
| Finkelstein, SD | 1 |
| Sayegh, R | 1 |
| Christensen, S | 1 |
| Swalsky, PA | 1 |
| Nemunaitis, J | 1 |
| Cox, J | 1 |
| Meyer, W | 1 |
| Courtney, A | 1 |
| Mues, G | 1 |
| Tsukuda, K | 1 |
| Tanino, M | 1 |
| Soga, H | 1 |
| Shimizu, N | 1 |
| Shimizu, K | 1 |
| Bauvy, C | 1 |
| Gane, P | 1 |
| Arico, S | 1 |
| Allgayer, H | 1 |
| Kolb, M | 1 |
| Stuber, V | 1 |
| Kruis, W | 1 |
| Barbieri, R | 1 |
| Ruisi, G | 1 |
| Atassi, G | 1 |
| Matsumoto, M | 1 |
| Tihan, T | 1 |
| Cory, JG | 1 |
| Jones, SB | 1 |
| Toews, ML | 1 |
| Turner, JT | 1 |
| Bylund, DB | 1 |
| Willoughby, HW | 1 |
| Maughan, GB | 1 |
| Tremblay, PC | 1 |
| Wood, N | 1 |
27 other studies available for adenine and Colonic Neoplasms
| Article | Year |
|---|---|
Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Beclin-1; Caspase 3; Cell Cycle Checkpoints; C | 2018 |
Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction.
Topics: Adenine; Antineoplastic Agents; CDC2 Protein Kinase; Cell Line, Tumor; Colonic Neoplasms; Humans; Or | 2019 |
A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related | 2013 |
Autophagy inhibition sensitizes WYE-354-induced anti-colon cancer activity in vitro and in vivo.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Colonic Neoplasms; | 2016 |
Inflammation increases oxidative DNA damage repair and stimulates preneoplastic changes in colons of newborn rats.
Topics: Adenine; Animals; Animals, Newborn; Arachidonate 12-Lipoxygenase; Colon; Colonic Neoplasms; Cyclooxy | 2016 |
Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells.
Topics: Adenine; Autophagy; Cell Division; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cysteine | 2008 |
Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells.
Topics: Adenine; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Blott | 2009 |
Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells.
Topics: Adenine; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygen | 2009 |
Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell.
Topics: Adenine; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Autophagy; bcl-2-Associated | 2010 |
Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells.
Topics: Adenine; Anticarcinogenic Agents; Apoptosis; Autophagy; Blotting, Western; Caspases; Cell Line, Tumo | 2010 |
Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer.
Topics: Adenine; Catalytic Domain; Colonic Neoplasms; Crystallography, X-Ray; DNA Glycosylases; Enzyme Stabi | 2009 |
A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy.
Topics: Adenine; Apoptosis; Autophagy; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; D | 2009 |
Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model.
Topics: Adenine; AMP-Activated Protein Kinase Kinases; Animals; Antimetabolites, Antineoplastic; Antineoplas | 2010 |
Dual role of autophagy in colon cancer cell survival.
Topics: Adenine; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Colonic Neoplasms; Fluorouracil; Hum | 2011 |
Association of interindividual differences in p14ARF promoter methylation with single nucleotide polymorphism in primary colorectal cancer.
Topics: Adenine; Colonic Neoplasms; CpG Islands; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytos | 2008 |
Amino-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H- dibenz[de,h]isoquinoline-1,3-diones. Synthesis, antitumor activity, and quantitative structure--activity relationship.
Topics: Adenine; Animals; Antineoplastic Agents; Cattle; Colonic Neoplasms; DNA; Doxorubicin; Heart Diseases | 1995 |
Autophagic degradation of N-linked glycoproteins is downregulated in differentiated human colon adenocarcinoma cells.
Topics: Adenine; Adenocarcinoma; Asparagine; Autophagy; Carbon Radioisotopes; Carcinogens; Cell Differentiat | 1993 |
Mutational heterogeneity among individual tumors in a case of multiple primary malignancy of the colon.
Topics: Adenine; Adenocarcinoma; Adenoma; Aged; Alleles; Base Sequence; Carcinoma; Codon; Colonic Neoplasms; | 1993 |
Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type.
Topics: Adenine; Adenocarcinoma; Aspartic Acid; Biology; Codon; Colonic Neoplasms; Gene Frequency; Genes, ra | 1993 |
Irinotecan hydrochloride (CPT-11) resistance identified by K-ras mutation in patients with progressive colon cancer after treatment with 5-fluorouracil (5-FU).
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phy | 1997 |
A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma.
Topics: 3T3 Cells; Adenine; Adenocarcinoma; Animals; Base Sequence; Cell Transformation, Neoplastic; Colonic | 2000 |
Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29.
Topics: Adenine; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Autophagy; Caspases; Colonic Neoplasms; | 2001 |
Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA.
Topics: Adenine; Animals; Cattle; Chenodeoxycholic Acid; Colon; Colonic Neoplasms; Deoxycholic Acid; DNA; DN | 2002 |
The antitumor activity and the structure of bis(adeninato-N9) diphenyltin(IV).
Topics: Adenine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Colonic Neoplasms; Female; Hum | 1991 |
Effect of ribonucleotide reductase inhibitors on the growth of human colon carcinoma HT-29 cells in culture.
Topics: Adenine; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Deoxyadenosines; Drug Screening As | 1990 |
Alpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production.
Topics: Adenine; Adenocarcinoma; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Cell Line; Colforsin; C | 1987 |
Determination of individual human tumour sensitivity to antitumour agents by tissue-slice incubation.
Topics: Adenine; Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma; Colonic Neoplasms; Cultu | 1971 |