adenine has been researched along with Cognitive Dysfunction in 7 studies
Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats." | 8.02 | INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021) |
| "This study was designed to explore the effect of 3-methyladenine (3-MA) on sevoflurane anesthesia-induced cognitive dysfunction." | 7.85 | The autophagy inhibitor 3-methyladenine restores sevoflurane anesthesiainduced cognitive dysfunction and neurons apoptosis. ( Bu, J; Hou, B; Li, G; Liang, Z; Xiao, X; Yang, L; Zhu, Y, 2017) |
| "This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats." | 4.02 | INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021) |
| "This study was designed to explore the effect of 3-methyladenine (3-MA) on sevoflurane anesthesia-induced cognitive dysfunction." | 3.85 | The autophagy inhibitor 3-methyladenine restores sevoflurane anesthesiainduced cognitive dysfunction and neurons apoptosis. ( Bu, J; Hou, B; Li, G; Liang, Z; Xiao, X; Yang, L; Zhu, Y, 2017) |
| "We report a pedigree of adult-onset Leigh syndrome (LS) with mitochondrial mutation 8344 A>G." | 1.40 | Adult onset Leigh syndrome with mitochondrial DNA 8344 A>G mutation. ( Han, JY; Lee, KW; Park, HK; Sung, JJ; Yoon, BN, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, L | 1 |
| Bi, Y | 1 |
| Xu, Y | 1 |
| Wu, Y | 1 |
| Du, X | 1 |
| Mou, Y | 1 |
| Chen, J | 1 |
| Ma, Z | 1 |
| Yang, Z | 1 |
| Feng, X | 1 |
| Deng, J | 1 |
| He, C | 1 |
| Li, R | 1 |
| Zhao, Y | 1 |
| Ge, Y | 1 |
| Zhang, Y | 1 |
| Song, C | 1 |
| Zhong, S | 1 |
| Jin, P | 1 |
| Deng, S | 1 |
| Tian, M | 1 |
| Lenahan, C | 1 |
| Wei, P | 1 |
| Wang, Y | 2 |
| Tan, J | 1 |
| Wen, H | 1 |
| Zhao, F | 1 |
| Gao, Y | 1 |
| Gong, Y | 1 |
| Sharma, V | 1 |
| Ounallah-Saad, H | 1 |
| Chakraborty, D | 1 |
| Hleihil, M | 1 |
| Sood, R | 1 |
| Barrera, I | 1 |
| Edry, E | 1 |
| Kolatt Chandran, S | 1 |
| Ben Tabou de Leon, S | 1 |
| Kaphzan, H | 1 |
| Rosenblum, K | 1 |
| Xiao, X | 1 |
| Zhu, Y | 1 |
| Bu, J | 1 |
| Li, G | 1 |
| Liang, Z | 1 |
| Yang, L | 1 |
| Hou, B | 1 |
| Zhao, L | 1 |
| Zhang, B | 1 |
| Cui, Y | 1 |
| Hou, C | 1 |
| Zeng, Q | 1 |
| Gao, T | 1 |
| Zhang, Z | 1 |
| Yu, J | 1 |
| Wang, A | 1 |
| Liu, H | 1 |
| Han, JY | 1 |
| Sung, JJ | 1 |
| Park, HK | 1 |
| Yoon, BN | 1 |
| Lee, KW | 1 |
7 other studies available for adenine and Cognitive Dysfunction
| Article | Year |
|---|---|
Suppression of CHOP Reduces Neuronal Apoptosis and Rescues Cognitive Impairment Induced by Intermittent Hypoxia by Inhibiting Bax and Bak Activation.
Topics: Adenine; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; | 2021 |
The Emerging Evidence for a Protective Role of Fucoidan from
Topics: Adenine; Aged; Animals; Cognitive Dysfunction; Female; Humans; Laminaria; Male; Memory Disorders; Mi | 2022 |
INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis.
Topics: Adenine; Animals; Anxiety; Cholic Acids; Cognitive Dysfunction; Cyclic AMP; Cyclic AMP Response Elem | 2021 |
Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties.
Topics: Adenine; Aging; Animals; Cognition; Cognitive Dysfunction; eIF-2 Kinase; Enzyme Inhibitors; Hippocam | 2018 |
The autophagy inhibitor 3-methyladenine restores sevoflurane anesthesiainduced cognitive dysfunction and neurons apoptosis.
Topics: Adenine; Anesthetics, Inhalation; Animals; Apoptosis; Autophagy; Cognitive Dysfunction; Gene Express | 2017 |
3-Methyladenine alleviates excessive iodine-induced cognitive impairment via suppression of autophagy in rat hippocampus.
Topics: Adenine; Animals; Autophagy; Cognitive Dysfunction; Female; Hippocampus; Iodine; Male; Malondialdehy | 2019 |
Adult onset Leigh syndrome with mitochondrial DNA 8344 A>G mutation.
Topics: Adenine; Adult; Age of Onset; Brain; Cognitive Dysfunction; Diffusion Magnetic Resonance Imaging; DN | 2014 |