adenine has been researched along with Cirrhosis in 90 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Colchicine inhibited tubulin polymerization and caspase-1 activation and attenuated kidney inflammation and fibrosis in a mouse model of adenine-induced KI." | 8.31 | Beneficiary Effects of Colchicine on Inflammation and Fibrosis in a Mouse Model of Kidney Injury. ( Arazi, E; Landau, D; Segev, Y; Shukri, N; Tobar, A, 2023) |
| "We investigated antifibrotic effects of capsaicin in two mouse renal fibrosis models as follows: C57BL/6J mice were subjected to unilateral ureteral obstruction (UUO) and fed with an adenine-rich diet." | 8.12 | Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling. ( Li, X; Liu, Z; Meng, D; Tang, S; Wang, H; Wang, W; Wu, Y; Xia, W; Zhang, J; Zhou, X, 2022) |
| " The characterizations were analyzed by physicochemical methods, and the renoprotections were processed in adenine-induced chronic kidney diseases (CKD) models of mice." | 8.02 | Renoprotective effects of enzyme-hydrolyzed polysaccharides from Auricularia polytricha on adenine-induced chronic kidney diseases in mice. ( Cui, W; Jia, L; Li, J; Pang, H; Song, X; Zhang, J, 2021) |
| "Progressive fibrosis accompanies all chronic renal disease, connective tissue growth factor (CTGF,) and platelet-derived growth factor-B, (PDGF-B,) play important roles in extra-cellular matrix abnormal accumulation, while endothelin-1 (ET-1) nitric oxide (NO,) are related to endothelial dysfunction, which mediates the progression of renal fibrosis." | 7.80 | Chinese herbal medicine Shenqi Detoxification Granule inhibits fibrosis in adenine induced chronic renal failure rats. ( Cai, P; Ma, H; Meng, H; Peng, M; Si, G; Xu, Y; Zhang, X, 2014) |
| "Adenine phosphoribosyltransferase deficiency in mice or an excessive oral intake of adenine leads to the accumulation of 2,8-dihydroxyadenine (DHA) in renal tubules and that causes progressive renal dysfunction accompanied by interstitial fibrosis." | 7.75 | Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model. ( Aizawa, R; Hori, M; Ozaki, H; Tamura, M, 2009) |
| " A 40-year-old liver transplant recipient with hepatitis B virus reinfection, resistance to lamivudine, and fibrosing cholestatic hepatitis complicated by terminal renal impairment and spontaneous bacterial peritonitis was treated with adefovir dipivoxil 10 mg after every dialysis." | 7.72 | Successful treatment of fibrosing cholestatic hepatitis using adefovir dipivoxil in a patient with cirrhosis and renal insufficiency. ( Barg-Hock, H; Becker, T; Bleck, JS; Bock, CT; Böker, KH; Flemming, P; Klempnauer, J; Manns, MP; Rosenau, J; Tillmann, HL; Trautwein, C, 2003) |
| " Here, CKD was developed by an oral dosage of adenine (AD) in the mice model." | 5.62 | Morin hydrate attenuates adenine-induced renal fibrosis via targeting cathepsin D signaling. ( Kang, SC; Sharma, C; Singh, MP, 2021) |
| "Renal fibrosis is a complication of kidney injury and associated with increased risk of morbidity and mortality." | 5.48 | Ameliorative effect of ursolic acid on renal fibrosis in adenine-induced chronic kidney disease in rats. ( Begum, J; Kumar, D; Kumar, P; Lingaraju, MC; Mathesh, K; Sharma, A; Singh, TU; Thakur, R, 2018) |
| "Renal fibrosis is a common pathological feature of the progression of chronic kidney disease." | 5.46 | Valproic acid attenuates renal fibrosis through the induction of autophagy. ( Doi, S; Doi, T; Kawaoka, K; Masaki, T; Nakashima, A; Ueno, T; Yamada, K, 2017) |
| "Colchicine inhibited tubulin polymerization and caspase-1 activation and attenuated kidney inflammation and fibrosis in a mouse model of adenine-induced KI." | 4.31 | Beneficiary Effects of Colchicine on Inflammation and Fibrosis in a Mouse Model of Kidney Injury. ( Arazi, E; Landau, D; Segev, Y; Shukri, N; Tobar, A, 2023) |
| "To develop a comprehensive therapy for heart failure, we used CRISPR-Cas9 adenine base editing to ablate the autophosphorylation site of CaMKIIδ." | 4.31 | Elimination of CaMKIIδ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice. ( Bassel-Duby, R; Caravia, XM; Chemello, F; Chen, K; Lebek, S; Liu, N; McAnally, JR; Olson, EN; Tan, W; Xu, L, 2023) |
| " We also investigated its efficacy in unilateral ureteral obstruction (UUO)-treated mice and in adenine-induced CKD rats." | 4.12 | Mucin-fused myeloid-derived growth factor (MYDGF164) exhibits a prolonged serum half-life and alleviates fibrosis in chronic kidney disease. ( Du, P; Wang, H; Wang, T; Yang, M; Yin, H, 2022) |
| "We investigated antifibrotic effects of capsaicin in two mouse renal fibrosis models as follows: C57BL/6J mice were subjected to unilateral ureteral obstruction (UUO) and fed with an adenine-rich diet." | 4.12 | Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling. ( Li, X; Liu, Z; Meng, D; Tang, S; Wang, H; Wang, W; Wu, Y; Xia, W; Zhang, J; Zhou, X, 2022) |
| "SKI protected against adenine-induced kidney injury and fibrosis and exerted anti-inflammatory, and antioxidant effects in CRF rats." | 4.12 | Protective effect and mechanism of Shenkang injection on adenine-induced chronic renal failure in rats. ( Chen, R; Sun, G; Sun, X; Xu, L; Zeng, W; Zhang, X, 2022) |
| " The efficacy of the CTGF vaccine on renal fibrosis was evaluated in adenine-induced CKD and unilateral ureteral obstruction (UUO) murine models." | 4.12 | Vaccination against connective tissue growth factor attenuates the development of renal fibrosis. ( Azegami, T; Hayashi, K; Hishikawa, A; Itoh, H; Nakamichi, R; Nakayama, T; Sugita, E; Yoshimoto, N, 2022) |
| " We used two animal models of renal fibrosis generated by a unilateral ureteral obstruction (UUO) and an adenine diet (AD) to investigate whether SAMiRNA-AREG inhibited renal fibrosis." | 4.02 | In vivo silencing of amphiregulin by a novel effective Self-Assembled-Micelle inhibitory RNA ameliorates renal fibrosis via inhibition of EGFR signals. ( Hwang, S; Kim, TR; Ko, Y; Lee, EY; Lee, JH; Park, HO; Park, JH; Son, B; Son, SS; Yun, SI, 2021) |
| " The characterizations were analyzed by physicochemical methods, and the renoprotections were processed in adenine-induced chronic kidney diseases (CKD) models of mice." | 4.02 | Renoprotective effects of enzyme-hydrolyzed polysaccharides from Auricularia polytricha on adenine-induced chronic kidney diseases in mice. ( Cui, W; Jia, L; Li, J; Pang, H; Song, X; Zhang, J, 2021) |
| "2% adenine diet for 14 weeks developed CKD with elevated plasma levels of TMAO, provision of a non-lethal inhibitor of gut microbial trimethylamine (TMA) production, iodomethylcholine (IMC), significantly reduced multiple markers of renal injury (plasma creatinine, cystatin C, FGF23, and TMAO), reduced histopathologic evidence of fibrosis, and markedly attenuated development of microalbuminuria." | 4.02 | Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice. ( Charugundla, S; Guo, F; Hazen, SL; Jia, X; Kaczor-Urbanowicz, KE; Lusis, AJ; Magyar, C; Miikeda, A; Nicholas, SB; Pellegrini, M; Shih, DM; Wang, Z; Zhang, W; Zhou, Z; Zuckerman, J, 2021) |
| " Mouse fibrotic kidney samples were collected from male C57BL/6J mice treated with an adenine-rich diet for 14 days or were subjected to 7 days of unilateral ureteral obstruction (UUO)." | 4.02 | Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys. ( Beyer, S; Boor, P; Djudjaj, S; Eckes, T; Gauer, S; Koch, A; Patyna, S; Pfeilschifter, J; Schaefer, L; Schwalm, S; Thomas, D; Trautmann, S, 2021) |
| " Adenine treatment reduced body weight, creatinine renal clearance, and increased water intake and urine output, as well as the plasma concentrations of urea and creatinine, neutrophil gelatinase-associated lipocalin, and N-acetyl-β-D-glucosaminidase activity, and albumin in urine." | 3.88 | The effect of sildenafil on rats with adenine-Induced chronic kidney disease. ( Adham, SA; Al Kalbani, J; Al Suleimani, Y; Al Za'abi, M; Ali, BH; Karaca, T; Manoj, P; Nemmar, A; Yasin, J, 2018) |
| "Adenine mice exhibited significantly higher mean serum urea, creatinine, and renal expression of the pro-inflammatory markers Interleukin-6 (IL-6), C-X-C motif chemokine 10 (CXCL10), and Interleukin-1β (IL-1β), in addition to prominent renal fibrosis and reduced renal Klotho gene expression compared to the control." | 3.88 | Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model. ( Baia, LC; de Borst, MH; Heilberg, IP; Henao Agudelo, JS; Machado, JR; Navis, GJ; Ormanji, MS; Santos, ARP; Saraiva Câmara, NO, 2018) |
| " Here, we studied whether a specific inhibitor of the Nlrp3 inflammasome, CP-456,773, can prevent kidney fibrosis in a murine model of crystal nephropathy induced by diets rich in oxalate or adenine." | 3.83 | An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice. ( Bartok, E; Boor, P; Dhana, E; Evers, BD; Franklin, BS; Hall, JP; Hartmann, G; Hornung, V; Knolle, PA; Kurts, C; Latz, E; Ludwig-Portugall, I; Primiano, MJ, 2016) |
| "Progressive fibrosis accompanies all chronic renal disease, connective tissue growth factor (CTGF,) and platelet-derived growth factor-B, (PDGF-B,) play important roles in extra-cellular matrix abnormal accumulation, while endothelin-1 (ET-1) nitric oxide (NO,) are related to endothelial dysfunction, which mediates the progression of renal fibrosis." | 3.80 | Chinese herbal medicine Shenqi Detoxification Granule inhibits fibrosis in adenine induced chronic renal failure rats. ( Cai, P; Ma, H; Meng, H; Peng, M; Si, G; Xu, Y; Zhang, X, 2014) |
| "Adenine overload promotes intratubular crystal precipitation and interstitial nephritis." | 3.79 | NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy. ( Arias, SC; Barlette, GP; Borges, RL; Camara, NO; de Almeida, DC; Fanelli, C; Fujihara, CK; Machado, FG; Malheiros, DM; Okabe, C; Zatz, R, 2013) |
| " In particular, we show that systemic injection of 3-methyladenine (3-MA) reduces muscle fibrosis, atrophy, apoptosis and increases muscle regeneration and muscle mass." | 3.77 | Autophagy is increased in laminin α2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A. ( Allamand, V; Carmignac, V; Durbeej, M; Elowsson, L; Gawlik, KI; Körner, Z; Matsumura, C; Svensson, M, 2011) |
| "Adenine phosphoribosyltransferase deficiency in mice or an excessive oral intake of adenine leads to the accumulation of 2,8-dihydroxyadenine (DHA) in renal tubules and that causes progressive renal dysfunction accompanied by interstitial fibrosis." | 3.75 | Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model. ( Aizawa, R; Hori, M; Ozaki, H; Tamura, M, 2009) |
| " A 40-year-old liver transplant recipient with hepatitis B virus reinfection, resistance to lamivudine, and fibrosing cholestatic hepatitis complicated by terminal renal impairment and spontaneous bacterial peritonitis was treated with adefovir dipivoxil 10 mg after every dialysis." | 3.72 | Successful treatment of fibrosing cholestatic hepatitis using adefovir dipivoxil in a patient with cirrhosis and renal insufficiency. ( Barg-Hock, H; Becker, T; Bleck, JS; Bock, CT; Böker, KH; Flemming, P; Klempnauer, J; Manns, MP; Rosenau, J; Tillmann, HL; Trautwein, C, 2003) |
| "Adenine phosphoribosyltransferase (APRT) deficiency in humans is an autosomal recessive syndrome characterized by the urinary excretion of adenine and the highly insoluble compound 2,8-dihydroxyadenine (DHA) that can produce kidney stones or renal failure." | 3.69 | Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis. ( Boivin, G; Chen, J; Davies, PM; Engle, SJ; Sahota, A; Simmonds, HA; Stambrook, PJ; Stockelman, MG; Tischfield, JA; Ying, MY; Yum, MN, 1996) |
| "Registered treatment for chronic hepatitis B currently consists of (pegylated) interferon, lamivudine and adefovir, while entecavir is expected to be licensed in the short term." | 2.43 | Antiviral treatment for chronic hepatitis B virus infection--immune modulation or viral suppression? ( Buster, EH; Janssen, HL, 2006) |
| "Renal fibrosis is the final manifestation of chronic kidney disease (CKD) regardless of etiology." | 1.91 | Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model. ( Kim, DA; Kim, M; Kong, KH; Lee, MR; Oh, HJ, 2023) |
| "Icariin at the dosage of 100 mg/kg/d and 200 mg/kg/d markedly ameliorated rat renal function in a dose-dependent manner." | 1.91 | Icariin, the main prenylflavonoid of Epimedii Folium, ameliorated chronic kidney disease by modulating energy metabolism via AMPK activation. ( Lu, J; Lv, C; Yang, W; Zhang, X; Zhao, Y, 2023) |
| "Renal fibrosis is the final stage of chronic kidney injury characterized by glomerulosclerosis and tubulointerstitial fibrosis with parenchymal destruction." | 1.72 | Nanoparticles Formulation Improves the Antifibrogenic Effect of Quercetin on an Adenine-Induced Model of Chronic Kidney Disease. ( Bastidas-Ramírez, BE; Gasca-Lozano, LE; Gurrola-Díaz, CM; Hernández-Ortega, LD; Martínez-Limón, FJ; Mena-Enríquez, M; Salazar-Montes, AM; Sánchez-Jaramillo, EA; Vargas-Guerrero, B; Vera-Cruz, JM, 2022) |
| "Adenine was used to establish a rat model of CKD, biochemical testing, histopathologic examination, ELISA, immunohistochemical assay, western blot assay, and fecal microbiota 16s rRNA analysis was used to test the effect of PNS on CKD rats." | 1.72 | Panax notoginseng saponins alleviate damage to the intestinal barrier and regulate levels of intestinal microbes in a rat model of chronic kidney disease. ( Fan, J; Ma, X; Mao, N; Ren, S; Xie, J; Zheng, Y, 2022) |
| "Kidney failure was induced chemically with an adenine-rich diet (0." | 1.72 | Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure. ( Borges, NA; Daleprane, JB; de Castro Resende, Â; Monteiro, EB; Monteiro, M; Soulage, CO, 2022) |
| "Renal fibrosis is an inevitable outcome of various manifestations of progressive chronic kidney diseases (CKD)." | 1.72 | The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice. ( Alolga, RN; Bian, XY; Chen, C; Jiang, H; Li, J; Liu, HL; Liu, SJ; Liu, YF; Shan, JJ; Si, ZL; Tan, NH; Wang, H; Wu, WH; Zhang, ZH; Zhou, W, 2022) |
| "Renal interstitial fibrosis is characterized by the development of myofibroblasts, originating from resident renal and immigrating cells." | 1.62 | Endothelin receptors in renal interstitial cells do not contribute to the development of fibrosis during experimental kidney disease. ( Broeker, KAE; Fuchs, MAA; Neder, TH; Schrankl, J; Wagner, C, 2021) |
| " Here, CKD was developed by an oral dosage of adenine (AD) in the mice model." | 1.62 | Morin hydrate attenuates adenine-induced renal fibrosis via targeting cathepsin D signaling. ( Kang, SC; Sharma, C; Singh, MP, 2021) |
| "Cardiorenal syndrome is a major cause of mortality in patients with chronic kidney disease (CKD)." | 1.56 | The guanylate cyclase C agonist linaclotide ameliorates the gut-cardio-renal axis in an adenine-induced mouse model of chronic kidney disease. ( Abe, T; Akiyama, Y; Asaji, K; Fukuda, S; Ho, HJ; Ito, S; Iwasaki, T; Kanemitsu, Y; Kikuchi, K; Kure, S; Matsuhashi, T; Mishima, E; Nanto-Hara, F; Oikawa, Y; Owada, Y; Saigusa, D; Soga, T; Suzuki, C; Suzuki, T; Tomioka, Y; Tsukimi, T, 2020) |
| "Renal fibrosis is an inevitable course of all kinds of progressive chronic kidney disease (CKD)." | 1.56 | 4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species. ( He, J; Tan, N; Tian, F; Wang, Z; Zhang, Z, 2020) |
| "Hyperuricemia is an independent risk factor for chronic kidney disease (CKD)." | 1.56 | Pharmacological inhibition of fatty acid-binding protein 4 alleviated kidney inflammation and fibrosis in hyperuricemic nephropathy. ( Feng, Y; Fu, P; Guo, F; Huang, R; Liao, D; Ma, L; Shi, M; Zeng, X, 2020) |
| "Renal fibrosis is one of the main causes of chronic kidney disease." | 1.56 | Knockdown of CK2α reduces ( Go, G; Lee, SH; Lim, JH; Yoon, YM; Yun, CW, 2020) |
| "Kidney fibrosis is one of the main pathological findings of progressive chronic kidney disease (CKD) although the pathogenesis of renal scar formation remains incompletely explained." | 1.51 | Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression. ( Calleros, L; de Frutos, S; García-Jérez, A; Griera, M; Hatem-Vaquero, M; Luengo, A; O'Valle, F; Rodríguez-Puyol, D; Rodríguez-Puyol, M, 2019) |
| "Kidney fibrosis was associated with upregulation of 6-keto-PGI2/TXB2 in the rat kidney tissue." | 1.51 | Comparison of the Effects of Indobufen and Warfarin in a Rat Model of Adenine-Induced Chronic Kidney Disease. ( Gong, J; He, Q; Jin, J; Li, Y; Lou, X; Zhao, L, 2019) |
| "Systemic sclerosis is a multisystem inflammatory and vascular lesion leading to extensive tissue fibrosis." | 1.51 | DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models. ( Fan, C; Feng, C; Li, H; Lu, H; Niu, L; Qi, Q; Tang, W; Wu, B; Wu, Y; Zhang, Z; Zuo, J, 2019) |
| "Renal fibrosis is a complication of kidney injury and associated with increased risk of morbidity and mortality." | 1.48 | Ameliorative effect of ursolic acid on renal fibrosis in adenine-induced chronic kidney disease in rats. ( Begum, J; Kumar, D; Kumar, P; Lingaraju, MC; Mathesh, K; Sharma, A; Singh, TU; Thakur, R, 2018) |
| "Renal fibrosis is a common pathogenic response to injury in chronic kidney disease (CKD)." | 1.48 | RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase. ( Choi, AM; Choi, ME; Chung, KP; Imamura, M; Moon, JS; Muthukumar, T; Nakahira, K; Ryter, SW; Shingarev, R, 2018) |
| "Renal fibrosis is a common pathological feature of the progression of chronic kidney disease." | 1.46 | Valproic acid attenuates renal fibrosis through the induction of autophagy. ( Doi, S; Doi, T; Kawaoka, K; Masaki, T; Nakashima, A; Ueno, T; Yamada, K, 2017) |
| "Chrysin did not cause any overt adverse effect on the treated rats." | 1.42 | Ameliorative effect of chrysin on adenine-induced chronic kidney disease in rats. ( Adham, SA; Al Za'abi, M; Ali, BH; Nemmar, A; Schupp, N; Waly, MI; Yasin, J, 2015) |
| " Both prophylactic and therapeutic dosing regimens were effective." | 1.30 | Chemokines, nitric oxide and antiarthritic effects of 9-(2-phosphonomethoxyethyl)adenine (Adefovir). ( Franková, D; Holý, A; Zídek, Z, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.11) | 18.7374 |
| 1990's | 2 (2.22) | 18.2507 |
| 2000's | 4 (4.44) | 29.6817 |
| 2010's | 35 (38.89) | 24.3611 |
| 2020's | 48 (53.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Ha, S | 2 |
| Jeong, S | 1 |
| Jang, CW | 1 |
| Kim, J | 3 |
| Im, DS | 1 |
| Chung, HY | 2 |
| Chung, KW | 2 |
| Ito, S | 3 |
| Manabe, E | 1 |
| Dai, Y | 1 |
| Ishihara, M | 1 |
| Tsujino, T | 1 |
| Zhou, Y | 1 |
| Wei, M | 1 |
| Zhang, M | 2 |
| Zhang, J | 4 |
| Tang, F | 1 |
| Wu, X | 1 |
| Bhatia, D | 1 |
| Capili, A | 1 |
| Nakahira, K | 2 |
| Muthukumar, T | 2 |
| Torres, LK | 1 |
| Choi, AMK | 1 |
| Choi, ME | 2 |
| Zhou, W | 2 |
| Chen, MM | 1 |
| Liu, HL | 2 |
| Si, ZL | 2 |
| Wu, WH | 2 |
| Jiang, H | 2 |
| Wang, LX | 1 |
| Vaziri, ND | 1 |
| An, XF | 1 |
| Su, K | 1 |
| Chen, C | 2 |
| Tan, NH | 2 |
| Zhang, ZH | 2 |
| Liu, Z | 1 |
| Wang, W | 1 |
| Li, X | 1 |
| Tang, S | 1 |
| Meng, D | 1 |
| Xia, W | 1 |
| Wang, H | 3 |
| Wu, Y | 2 |
| Zhou, X | 2 |
| Samynathan, R | 1 |
| Subramanian, U | 1 |
| Venkidasamy, B | 1 |
| Shariati, MA | 1 |
| Chung, IM | 1 |
| Thiruvengadam, M | 1 |
| Liu, B | 1 |
| Deng, J | 1 |
| Jie, X | 1 |
| Lu, F | 1 |
| Liu, X | 2 |
| Zhang, D | 1 |
| Du, P | 1 |
| Wang, T | 1 |
| Yang, M | 1 |
| Yin, H | 1 |
| Sánchez-Jaramillo, EA | 1 |
| Gasca-Lozano, LE | 1 |
| Vera-Cruz, JM | 1 |
| Hernández-Ortega, LD | 1 |
| Gurrola-Díaz, CM | 1 |
| Bastidas-Ramírez, BE | 1 |
| Vargas-Guerrero, B | 1 |
| Mena-Enríquez, M | 1 |
| Martínez-Limón, FJ | 1 |
| Salazar-Montes, AM | 1 |
| Mendieta-Condado, E | 1 |
| Villaseñor-Tapia, EC | 1 |
| Gálvez-Gastelum, FJ | 1 |
| Yáñez-Sánchez, I | 1 |
| Pizano-Martínez, O | 1 |
| Canales-Aguirre, A | 1 |
| Márquez-Aguirre, AL | 1 |
| Chen, R | 1 |
| Xu, L | 2 |
| Zhang, X | 3 |
| Sun, G | 1 |
| Zeng, W | 1 |
| Sun, X | 1 |
| Nakayama, T | 1 |
| Azegami, T | 1 |
| Hayashi, K | 1 |
| Hishikawa, A | 1 |
| Yoshimoto, N | 1 |
| Nakamichi, R | 1 |
| Sugita, E | 1 |
| Itoh, H | 1 |
| Kim, H | 1 |
| Nam, BY | 1 |
| Park, J | 1 |
| Song, S | 1 |
| Kim, WK | 1 |
| Lee, K | 1 |
| Nam, TW | 1 |
| Park, JT | 1 |
| Yoo, TH | 1 |
| Kang, SW | 1 |
| Ko, G | 1 |
| Han, SH | 1 |
| Haritha, CV | 1 |
| Lingaraju, MC | 2 |
| Mathesh, K | 2 |
| Jadhav, SE | 1 |
| Shyamkumar, TS | 1 |
| Aneesha, VA | 1 |
| Parida, S | 1 |
| Singh, TU | 2 |
| Kumar, D | 3 |
| Wollenhaupt, J | 1 |
| Frisch, J | 1 |
| Harlacher, E | 1 |
| Wong, DWL | 2 |
| Jin, H | 1 |
| Schulte, C | 1 |
| Vondenhoff, S | 1 |
| Moellmann, J | 2 |
| Klinkhammer, BM | 3 |
| Zhang, L | 1 |
| Baleanu-Curaj, A | 1 |
| Liehn, EA | 1 |
| Speer, T | 1 |
| Kazakov, A | 1 |
| Werner, C | 1 |
| van der Vorst, EPC | 1 |
| Selejan, SR | 1 |
| Hohl, M | 1 |
| Böhm, M | 1 |
| Kramann, R | 1 |
| Biessen, EAL | 1 |
| Lehrke, M | 2 |
| Marx, N | 2 |
| Jankowski, J | 2 |
| Maack, C | 1 |
| Boor, P | 5 |
| Prates Roma, L | 1 |
| Noels, H | 2 |
| Liu, YF | 1 |
| Alolga, RN | 1 |
| Liu, SJ | 1 |
| Bian, XY | 1 |
| Shan, JJ | 1 |
| Li, J | 2 |
| Yamamura, Y | 1 |
| Iwata, Y | 1 |
| Furuichi, K | 1 |
| Kato, T | 1 |
| Yamamoto, N | 1 |
| Horikoshi, K | 1 |
| Ogura, H | 1 |
| Sato, K | 1 |
| Oshima, M | 1 |
| Nakagawa, S | 1 |
| Miyagawa, T | 1 |
| Kitajima, S | 1 |
| Toyama, T | 1 |
| Hara, A | 1 |
| Sakai, N | 1 |
| Shimizu, M | 1 |
| Horike, S | 1 |
| Daikoku, T | 1 |
| Nishinakamura, R | 1 |
| Wada, T | 1 |
| Liu, C | 1 |
| Li, S | 2 |
| Ji, S | 1 |
| Zheng, F | 1 |
| Guan, Y | 1 |
| Yang, G | 1 |
| Chen, L | 1 |
| Xie, J | 1 |
| Ma, X | 1 |
| Zheng, Y | 1 |
| Mao, N | 1 |
| Ren, S | 1 |
| Fan, J | 1 |
| Lin, CY | 1 |
| Wang, CC | 1 |
| Loh, JZ | 1 |
| Chiang, TC | 1 |
| Weng, TI | 1 |
| Chan, DC | 1 |
| Hung, KY | 1 |
| Chiang, CK | 1 |
| Liu, SH | 1 |
| Kim, DA | 3 |
| Lee, MR | 3 |
| Oh, HJ | 3 |
| Kim, M | 3 |
| Kong, KH | 3 |
| Monteiro, EB | 3 |
| Borges, NA | 3 |
| Monteiro, M | 3 |
| de Castro Resende, Â | 3 |
| Daleprane, JB | 3 |
| Soulage, CO | 3 |
| Li, C | 2 |
| Huang, H | 1 |
| Wang, R | 1 |
| Zhang, C | 1 |
| Huang, S | 1 |
| Wu, J | 1 |
| Mo, P | 1 |
| Yu, H | 2 |
| Chen, J | 2 |
| Zhao, Y | 2 |
| Yang, W | 1 |
| Lv, C | 1 |
| Lu, J | 2 |
| Lin, Y | 1 |
| Wei, J | 1 |
| Zhang, Y | 1 |
| Huang, J | 1 |
| Wang, S | 1 |
| Luo, Q | 1 |
| Ji, L | 1 |
| Landau, D | 1 |
| Shukri, N | 1 |
| Arazi, E | 1 |
| Tobar, A | 1 |
| Segev, Y | 1 |
| Huang, X | 1 |
| Gao, L | 1 |
| Deng, R | 1 |
| Peng, Y | 1 |
| Wu, S | 1 |
| Krehl, K | 1 |
| Hahndorf, J | 1 |
| Stolzenburg, N | 1 |
| Taupitz, M | 1 |
| Braun, J | 1 |
| Sack, I | 1 |
| Schnorr, J | 1 |
| Guo, J | 1 |
| Krueger, K | 1 |
| Buhl, EM | 1 |
| Dehairs, J | 1 |
| Swinnen, JV | 1 |
| Lebherz, C | 1 |
| Son, M | 1 |
| Kim, D | 2 |
| Kim, MJ | 1 |
| Kim, B | 1 |
| Lebek, S | 1 |
| Caravia, XM | 1 |
| Chemello, F | 1 |
| Tan, W | 1 |
| McAnally, JR | 1 |
| Chen, K | 1 |
| Liu, N | 2 |
| Bassel-Duby, R | 1 |
| Olson, EN | 1 |
| Nanto-Hara, F | 1 |
| Kanemitsu, Y | 1 |
| Fukuda, S | 1 |
| Kikuchi, K | 1 |
| Asaji, K | 1 |
| Saigusa, D | 1 |
| Iwasaki, T | 1 |
| Ho, HJ | 1 |
| Mishima, E | 1 |
| Suzuki, T | 1 |
| Suzuki, C | 1 |
| Tsukimi, T | 1 |
| Matsuhashi, T | 1 |
| Oikawa, Y | 1 |
| Akiyama, Y | 1 |
| Kure, S | 1 |
| Owada, Y | 1 |
| Tomioka, Y | 1 |
| Soga, T | 1 |
| Abe, T | 1 |
| Zhang, Z | 2 |
| Wu, B | 1 |
| Qi, Q | 1 |
| Li, H | 1 |
| Lu, H | 1 |
| Fan, C | 1 |
| Feng, C | 1 |
| Zuo, J | 1 |
| Niu, L | 1 |
| Tang, W | 1 |
| Tian, F | 1 |
| Wang, Z | 2 |
| He, J | 1 |
| Tan, N | 1 |
| Awad, AM | 1 |
| Saleh, MA | 1 |
| Abu-Elsaad, NM | 1 |
| Ibrahim, TM | 1 |
| Shi, M | 1 |
| Guo, F | 2 |
| Liao, D | 1 |
| Huang, R | 1 |
| Feng, Y | 1 |
| Zeng, X | 1 |
| Ma, L | 1 |
| Fu, P | 1 |
| Eckes, T | 1 |
| Trautmann, S | 1 |
| Djudjaj, S | 1 |
| Beyer, S | 1 |
| Patyna, S | 1 |
| Schwalm, S | 1 |
| Gauer, S | 1 |
| Thomas, D | 1 |
| Schaefer, L | 1 |
| Koch, A | 1 |
| Pfeilschifter, J | 1 |
| Yoon, YM | 1 |
| Go, G | 1 |
| Yun, CW | 1 |
| Lim, JH | 1 |
| Lee, SH | 1 |
| Yuan, H | 1 |
| Zheng, C | 1 |
| Zhu, L | 1 |
| Song, Z | 1 |
| Dai, L | 1 |
| Hu, Q | 1 |
| Wang, L | 1 |
| Chen, Y | 2 |
| Xiong, J | 1 |
| Contreras-Salinas, H | 1 |
| Meza-Rios, A | 1 |
| García-Bañuelos, J | 2 |
| Sandoval-Rodriguez, A | 2 |
| Sanchez-Orozco, L | 1 |
| García-Benavides, L | 2 |
| De la Rosa-Bibiano, R | 1 |
| Monroy Ramirez, HC | 1 |
| Gutiérrez-Cuevas, J | 1 |
| Santos-Garcia, A | 1 |
| Armendariz-Borunda, J | 2 |
| Singh, MP | 1 |
| Sharma, C | 1 |
| Kang, SC | 1 |
| Cai, H | 1 |
| Wang, J | 1 |
| Luo, Y | 1 |
| Wang, F | 1 |
| He, G | 1 |
| Zhou, G | 1 |
| Peng, X | 1 |
| Song, X | 1 |
| Pang, H | 1 |
| Cui, W | 1 |
| Jia, L | 1 |
| Zhang, W | 1 |
| Miikeda, A | 1 |
| Zuckerman, J | 1 |
| Jia, X | 1 |
| Charugundla, S | 1 |
| Zhou, Z | 1 |
| Kaczor-Urbanowicz, KE | 1 |
| Magyar, C | 1 |
| Pellegrini, M | 1 |
| Hazen, SL | 1 |
| Nicholas, SB | 1 |
| Lusis, AJ | 1 |
| Shih, DM | 1 |
| Son, SS | 1 |
| Hwang, S | 1 |
| Park, JH | 1 |
| Ko, Y | 1 |
| Yun, SI | 1 |
| Lee, JH | 1 |
| Son, B | 1 |
| Kim, TR | 1 |
| Park, HO | 1 |
| Lee, EY | 1 |
| Belliere, J | 1 |
| Casemayou, A | 1 |
| Colliou, E | 1 |
| El Hachem, H | 1 |
| Kounde, C | 1 |
| Piedrafita, A | 1 |
| Feuillet, G | 1 |
| Schanstra, JP | 1 |
| Faguer, S | 1 |
| Tang, H | 1 |
| Zhang, P | 1 |
| Zeng, L | 1 |
| Xie, L | 1 |
| Chen, B | 1 |
| Neder, TH | 1 |
| Schrankl, J | 1 |
| Fuchs, MAA | 1 |
| Broeker, KAE | 1 |
| Wagner, C | 1 |
| Zhang, CY | 1 |
| Zhu, JY | 1 |
| Ye, Y | 1 |
| Zhang, LJ | 1 |
| Wang, SJ | 1 |
| Song, YN | 1 |
| Zhang, H | 1 |
| Rivera-Valdés, JJ | 1 |
| Salazar-Montes, A | 1 |
| Dominguez-Rosales, A | 1 |
| Imamura, M | 1 |
| Moon, JS | 1 |
| Chung, KP | 1 |
| Shingarev, R | 1 |
| Ryter, SW | 1 |
| Choi, AM | 1 |
| Thakur, R | 1 |
| Sharma, A | 1 |
| Begum, J | 1 |
| Kumar, P | 1 |
| Buchtler, S | 1 |
| Grill, A | 1 |
| Hofmarksrichter, S | 1 |
| Stöckert, P | 1 |
| Schiechl-Brachner, G | 1 |
| Rodriguez Gomez, M | 1 |
| Neumayer, S | 1 |
| Schmidbauer, K | 1 |
| Talke, Y | 1 |
| Medvinsky, A | 1 |
| Renner, K | 1 |
| Castrop, H | 1 |
| Mack, M | 1 |
| Li, B | 1 |
| Sun, Y | 1 |
| Wang, JP | 1 |
| Chi, RF | 1 |
| Wang, K | 1 |
| Yang, ZJ | 1 |
| Qin, FZ | 1 |
| Fan, B | 1 |
| Henao Agudelo, JS | 1 |
| Baia, LC | 1 |
| Ormanji, MS | 1 |
| Santos, ARP | 1 |
| Machado, JR | 1 |
| Saraiva Câmara, NO | 1 |
| Navis, GJ | 1 |
| de Borst, MH | 1 |
| Heilberg, IP | 1 |
| Ali, BH | 2 |
| Al Za'abi, M | 2 |
| Adham, SA | 2 |
| Al Suleimani, Y | 1 |
| Karaca, T | 1 |
| Manoj, P | 1 |
| Al Kalbani, J | 1 |
| Yasin, J | 2 |
| Nemmar, A | 2 |
| Bao, J | 1 |
| Shi, Y | 1 |
| Tao, M | 1 |
| Zhuang, S | 1 |
| Yuan, W | 1 |
| de Frutos, S | 1 |
| Luengo, A | 1 |
| García-Jérez, A | 1 |
| Hatem-Vaquero, M | 1 |
| Griera, M | 1 |
| O'Valle, F | 1 |
| Rodríguez-Puyol, M | 1 |
| Rodríguez-Puyol, D | 1 |
| Calleros, L | 1 |
| Sueyoshi, M | 1 |
| Fukunaga, M | 1 |
| Mei, M | 1 |
| Nakajima, A | 1 |
| Tanaka, G | 1 |
| Murase, T | 1 |
| Narita, Y | 1 |
| Hirata, S | 1 |
| Kadowaki, D | 1 |
| Belghasem, ME | 1 |
| A'amar, O | 1 |
| Roth, D | 1 |
| Walker, J | 1 |
| Arinze, N | 1 |
| Richards, SM | 1 |
| Francis, JM | 1 |
| Salant, DJ | 1 |
| Chitalia, VC | 1 |
| Bigio, IJ | 1 |
| Lou, X | 1 |
| Jin, J | 1 |
| Gong, J | 1 |
| Zhao, L | 1 |
| Li, Y | 1 |
| He, Q | 1 |
| Zhao, YY | 3 |
| Feng, YL | 1 |
| Bai, X | 3 |
| Tan, XJ | 2 |
| Lin, RC | 3 |
| Mei, Q | 2 |
| Okabe, C | 1 |
| Borges, RL | 1 |
| de Almeida, DC | 1 |
| Fanelli, C | 1 |
| Barlette, GP | 1 |
| Machado, FG | 1 |
| Arias, SC | 1 |
| Malheiros, DM | 1 |
| Camara, NO | 1 |
| Zatz, R | 1 |
| Fujihara, CK | 1 |
| Wang, B | 1 |
| Jha, JC | 1 |
| Hagiwara, S | 1 |
| McClelland, AD | 1 |
| Jandeleit-Dahm, K | 1 |
| Thomas, MC | 1 |
| Cooper, ME | 1 |
| Kantharidis, P | 1 |
| Hamasaki, Y | 1 |
| Doi, K | 1 |
| Maeda-Mamiya, R | 1 |
| Ogasawara, E | 1 |
| Katagiri, D | 1 |
| Tanaka, T | 1 |
| Yamamoto, T | 1 |
| Sugaya, T | 1 |
| Nangaku, M | 1 |
| Noiri, E | 1 |
| Calvaruso, V | 1 |
| Craxì, A | 1 |
| Peng, M | 1 |
| Cai, P | 1 |
| Ma, H | 1 |
| Meng, H | 1 |
| Xu, Y | 1 |
| Si, G | 1 |
| Yamada, S | 1 |
| Tatsumoto, N | 1 |
| Tokumoto, M | 1 |
| Noguchi, H | 1 |
| Ooboshi, H | 1 |
| Kitazono, T | 1 |
| Tsuruya, K | 1 |
| Ghavami, S | 1 |
| Cunnington, RH | 1 |
| Gupta, S | 1 |
| Yeganeh, B | 1 |
| Filomeno, KL | 1 |
| Freed, DH | 1 |
| Chen, S | 1 |
| Klonisch, T | 1 |
| Halayko, AJ | 1 |
| Ambrose, E | 1 |
| Singal, R | 1 |
| Dixon, IM | 1 |
| Massó-Vallés, D | 1 |
| Jauset, T | 1 |
| Serrano, E | 1 |
| Sodir, NM | 1 |
| Pedersen, K | 1 |
| Affara, NI | 1 |
| Whitfield, JR | 1 |
| Beaulieu, ME | 1 |
| Evan, GI | 1 |
| Elias, L | 1 |
| Arribas, J | 1 |
| Soucek, L | 1 |
| Waly, MI | 1 |
| Schupp, N | 1 |
| Ludwig-Portugall, I | 1 |
| Bartok, E | 1 |
| Dhana, E | 1 |
| Evers, BD | 1 |
| Primiano, MJ | 1 |
| Hall, JP | 1 |
| Franklin, BS | 1 |
| Knolle, PA | 1 |
| Hornung, V | 1 |
| Hartmann, G | 1 |
| Latz, E | 1 |
| Kurts, C | 1 |
| Mazumder, MK | 1 |
| Giri, A | 1 |
| Kumar, S | 1 |
| Borah, A | 1 |
| Shi, H | 2 |
| Ren, F | 1 |
| Chen, D | 1 |
| Duan, Z | 1 |
| Kawaoka, K | 1 |
| Doi, S | 1 |
| Nakashima, A | 1 |
| Yamada, K | 1 |
| Ueno, T | 1 |
| Doi, T | 1 |
| Masaki, T | 1 |
| Hayashi, S | 1 |
| Oe, Y | 1 |
| Fushima, T | 1 |
| Sato, E | 1 |
| Sato, H | 1 |
| Takahashi, N | 1 |
| Tamura, M | 1 |
| Aizawa, R | 1 |
| Hori, M | 1 |
| Ozaki, H | 1 |
| Cholongitas, E | 1 |
| Papatheodoridis, GV | 1 |
| Manesis, EK | 1 |
| Petraki, K | 1 |
| Tiniakos, D | 1 |
| Hadziyannis, SJ | 1 |
| Carmignac, V | 1 |
| Svensson, M | 1 |
| Körner, Z | 1 |
| Elowsson, L | 1 |
| Matsumura, C | 1 |
| Gawlik, KI | 1 |
| Allamand, V | 1 |
| Durbeej, M | 1 |
| Kim, WY | 1 |
| Nam, SA | 1 |
| Song, HC | 1 |
| Ko, JS | 1 |
| Park, SH | 1 |
| Kim, HL | 1 |
| Choi, EJ | 1 |
| Kim, YS | 1 |
| Kim, YK | 1 |
| Yen, CH | 1 |
| Lin, KC | 1 |
| Leu, S | 1 |
| Sun, CK | 1 |
| Chang, LT | 1 |
| Chai, HT | 1 |
| Chung, SY | 1 |
| Chang, HW | 1 |
| Ko, SF | 1 |
| Chen, YT | 1 |
| Yip, HK | 1 |
| Cheng, XL | 2 |
| Wei, F | 2 |
| Tillmann, HL | 1 |
| Bock, CT | 1 |
| Bleck, JS | 1 |
| Rosenau, J | 1 |
| Böker, KH | 1 |
| Barg-Hock, H | 1 |
| Becker, T | 1 |
| Trautwein, C | 1 |
| Klempnauer, J | 1 |
| Flemming, P | 1 |
| Manns, MP | 1 |
| Traboulsi, EI | 1 |
| Buster, EH | 1 |
| Janssen, HL | 1 |
| Engle, SJ | 1 |
| Stockelman, MG | 1 |
| Boivin, G | 1 |
| Yum, MN | 1 |
| Davies, PM | 1 |
| Ying, MY | 1 |
| Sahota, A | 1 |
| Simmonds, HA | 1 |
| Stambrook, PJ | 1 |
| Tischfield, JA | 1 |
| Zídek, Z | 1 |
| Franková, D | 1 |
| Holý, A | 1 |
| Yokozawa, T | 1 |
| Zheng, PD | 1 |
| Oura, H | 1 |
| Koizumi, F | 1 |
2 reviews available for adenine and Cirrhosis
| Article | Year |
|---|---|
Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible?
Topics: Adenine; Administration, Oral; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Guanine; Hepat | 2014 |
Antiviral treatment for chronic hepatitis B virus infection--immune modulation or viral suppression?
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Genotype; Hepatitis B e Antigens; He | 2006 |
88 other studies available for adenine and Cirrhosis
| Article | Year |
|---|---|
Comparison of two different toxin-induced kidney fibrosis models in terms of inflammatory responses.
Topics: Adenine; Animals; Cytokines; Disease Models, Animal; Fibrosis; Folic Acid; Inflammation; Male; Mice; | 2021 |
Juzentaihoto improves adenine-induced chronic renal failure in BALB/c mice via suppression of renal fibrosis and inflammation.
Topics: Adenine; Administration, Oral; Animals; Disease Models, Animal; Disease Progression; Drugs, Chinese | 2022 |
Adefovir accumulation in the renal interstitium triggers mast cell degranulation and promotes renal interstitial fibrosis.
Topics: Adenine; Animals; Cell Degranulation; Disease Models, Animal; Fibrosis; Humans; Kidney Diseases; Kid | 2022 |
Conditional deletion of myeloid-specific mitofusin 2 but not mitofusin 1 promotes kidney fibrosis.
Topics: Adenine; Animals; Female; Fibrosis; GTP Phosphohydrolases; Humans; Kidney; Male; Mice; Mitochondrial | 2022 |
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
Topics: Adenine; Animals; Artemisinins; Azacitidine; beta Catenin; Biotin; DNA; DNA Modification Methylases; | 2022 |
Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling.
Topics: Adenine; Animals; Cadherins; Capsaicin; Disease Models, Animal; Fibrosis; Kidney; Kidney Diseases; M | 2022 |
S-Allylcysteine (SAC) Exerts Renoprotective Effects via Regulation of TGF- β1/Smad3 Pathway Mediated Matrix Remodeling in Chronic Renal Failure.
Topics: Adenine; Aged; Animals; Cysteine; Fibrosis; Humans; Kidney Failure, Chronic; Rats; Rats, Wistar; Ren | 2022 |
Protective effects of the Bupi Yishen formula on renal fibrosis through PI3K/AKT signaling inhibition.
Topics: Adenine; Animals; Drugs, Chinese Herbal; Fibrosis; Humans; Molecular Docking Simulation; Phosphatidy | 2022 |
Mucin-fused myeloid-derived growth factor (MYDGF164) exhibits a prolonged serum half-life and alleviates fibrosis in chronic kidney disease.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Half-Life; Humans; Intercellular Signaling Pepti | 2022 |
Nanoparticles Formulation Improves the Antifibrogenic Effect of Quercetin on an Adenine-Induced Model of Chronic Kidney Disease.
Topics: Adenine; Animals; Antioxidants; Fibrosis; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Quercetin; | 2022 |
Effects of Etanercept on TNF-
Topics: Adenine; Animals; Atrophy; Etanercept; Fibrosis; Rats; Renal Insufficiency, Chronic; Tumor Necrosis | 2022 |
Protective effect and mechanism of Shenkang injection on adenine-induced chronic renal failure in rats.
Topics: Adenine; Animals; Drugs, Chinese Herbal; Fibrosis; Kidney; Kidney Failure, Chronic; Rats; Rats, Spra | 2022 |
Vaccination against connective tissue growth factor attenuates the development of renal fibrosis.
Topics: Adenine; Animals; Connective Tissue Growth Factor; Fibrosis; Kidney; Kidney Diseases; Mice; Renal In | 2022 |
Lactobacillus acidophilus KBL409 Reduces Kidney Fibrosis via Immune Modulatory Effects in Mice with Chronic Kidney Disease.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Kidney; Lactobacillus acidophilus; Mice; Mice, I | 2022 |
PRE-084 ameliorates adenine-induced renal fibrosis in rats.
Topics: Adenine; Animals; Creatinine; Fibrosis; Keratins; Kidney Diseases; Matrix Metalloproteinase 2; Morph | 2022 |
Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Apolipoproteins E; Cardiomyopathies; Disease Models, Ani | 2022 |
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice.
Topics: Adenine; Animals; Bacteroides fragilis; Biological Products; Disease Models, Animal; Fibrosis; Gastr | 2022 |
Kif26b contributes to the progression of interstitial fibrosis via migration and myofibroblast differentiation in renal fibroblast.
Topics: Actins; Adenine; Animals; Cell Differentiation; Cell Movement; Collagen; Connective Tissue Growth Fa | 2022 |
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis.
Topics: Adenine; Animals; Fibrosis; Glutathione; Homeostasis; Homocysteine; Kidney; Mice; Renal Insufficienc | 2023 |
Panax notoginseng saponins alleviate damage to the intestinal barrier and regulate levels of intestinal microbes in a rat model of chronic kidney disease.
Topics: Adenine; Animals; Fibrosis; Intestines; Panax notoginseng; Rats; Renal Insufficiency, Chronic; RNA, | 2022 |
Therapeutic Ultrasound Halts Progression of Chronic Kidney Disease In Vivo via the Regulation of Markers Associated with Renal Epithelial-Mesenchymal Transition and Senescence.
Topics: Adenine; Animals; Biomarkers; Epithelial-Mesenchymal Transition; Fibrosis; Kidney; Mice; Renal Insuf | 2022 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Effects of long-term tubular HIF-2α overexpression on progressive renal fibrosis in a chronic kidney disease model.
Topics: Adenine; Animals; Basic Helix-Loop-Helix Transcription Factors; Cadherins; Fibronectins; Fibrosis; H | 2023 |
Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure.
Topics: Adenine; Animals; Antioxidants; Fibrosis; Humans; Kidney; Male; Mice; Plant Extracts; Polyphenols; R | 2022 |
Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure.
Topics: Adenine; Animals; Antioxidants; Fibrosis; Humans; Kidney; Male; Mice; Plant Extracts; Polyphenols; R | 2022 |
Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure.
Topics: Adenine; Animals; Antioxidants; Fibrosis; Humans; Kidney; Male; Mice; Plant Extracts; Polyphenols; R | 2022 |
Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure.
Topics: Adenine; Animals; Antioxidants; Fibrosis; Humans; Kidney; Male; Mice; Plant Extracts; Polyphenols; R | 2022 |
Jian-Pi-Yi-Shen formula restores iron metabolism from dysregulation in anemic rats with adenine-induced nephropathy.
Topics: Adenine; Anemia; Animals; Fibrosis; Hepcidins; Iron; Rats; Renal Insufficiency, Chronic | 2023 |
Icariin, the main prenylflavonoid of Epimedii Folium, ameliorated chronic kidney disease by modulating energy metabolism via AMPK activation.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Energy Metabolism; Fibrosis; Kidney; Male; Rats; Ra | 2023 |
Shen Qi Wan attenuates renal interstitial fibrosis through upregulating AQP1.
Topics: Adenine; Animals; Aquaporin 1; Cell Line; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; | 2023 |
Beneficiary Effects of Colchicine on Inflammation and Fibrosis in a Mouse Model of Kidney Injury.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Caspase 1; Colchicine; Disease Models, Animal; Fibrosis; | 2023 |
Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Glucose; Kidney; Mice; Pentose Phosphate Pathway | 2023 |
Characterization of renal fibrosis in rats with chronic kidney disease by in vivo tomoelastography.
Topics: Adenine; Animals; Collagen; Elasticity Imaging Techniques; Fibrosis; Kidney; Rats; Renal Insufficien | 2023 |
2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function.
Topics: Adenine; Animals; Fibrosis; Inflammation; Kidney; Mice; Mice, Inbred C57BL; Mitochondria; Renal Insu | 2024 |
TLR7 activation by miR-21 promotes renal fibrosis by activating the pro-inflammatory signaling pathway in tubule epithelial cells.
Topics: Adenine; Animals; Epithelial Cells; Fibrosis; Inflammation; Kidney Diseases; Mice; MicroRNAs; NF-kap | 2023 |
Elimination of CaMKIIδ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice.
Topics: Adenine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; CRISPR-Cas Systems; Fibrosis; | 2023 |
The guanylate cyclase C agonist linaclotide ameliorates the gut-cardio-renal axis in an adenine-induced mouse model of chronic kidney disease.
Topics: Adenine; Animals; Cardio-Renal Syndrome; Disease Models, Animal; Disease Progression; Fibrosis; Gast | 2020 |
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models.
Topics: Adenine; Animals; Bleomycin; Butyrates; Cell Line; Cells, Cultured; Dermis; Disease Models, Animal; | 2019 |
4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species.
Topics: Adenine; Animals; Antioxidants; Autophagy; Fibrosis; Humans; Kidney Diseases; Male; Protective Agent | 2020 |
Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Humans; Kidney; Kidney Diseases; MAP Kinase Sign | 2020 |
Pharmacological inhibition of fatty acid-binding protein 4 alleviated kidney inflammation and fibrosis in hyperuricemic nephropathy.
Topics: Adenine; Animals; Biphenyl Compounds; Cytokines; Fatty Acid-Binding Proteins; Fibrosis; Hepatitis A | 2020 |
Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys.
Topics: Actins; Adenine; Aged; Animals; Biomarkers; Ceramides; Collagen Type I; Collagen Type I, alpha 1 Cha | 2021 |
Knockdown of CK2α reduces
Topics: Adenine; Animals; Casein Kinase II; Cell Line; Cellular Senescence; Cresols; Disease Models, Animal; | 2020 |
Contribution of TFEB-mediated autophagy to tubulointerstitial fibrosis in mice with adenine-induced chronic kidney disease.
Topics: Adenine; Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line; | 2021 |
Fibrosis regression is induced by AdhMMP8 in a murine model of chronic kidney injury.
Topics: Adenine; Adenoviridae; Animals; Disease Models, Animal; Fibrosis; Gene Expression Regulation; HEK293 | 2020 |
Morin hydrate attenuates adenine-induced renal fibrosis via targeting cathepsin D signaling.
Topics: Adenine; Animals; Cathepsin D; Collagen; Extracellular Matrix; Fibrosis; Flavonoids; Kidney; Kidney | 2021 |
Lindera aggregata intervents adenine-induced chronic kidney disease by mediating metabolism and TGF-β/Smad signaling pathway.
Topics: Adenine; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fibrosis; Humans; Kid | 2021 |
Renoprotective effects of enzyme-hydrolyzed polysaccharides from Auricularia polytricha on adenine-induced chronic kidney diseases in mice.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; | 2021 |
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice.
Topics: Adenine; Albuminuria; Animals; Cardiomegaly; Choline; Disease Models, Animal; Female; Fibroblast Gro | 2021 |
In vivo silencing of amphiregulin by a novel effective Self-Assembled-Micelle inhibitory RNA ameliorates renal fibrosis via inhibition of EGFR signals.
Topics: Adenine; Amphiregulin; Animals; Cell Adhesion Molecules; Cytokines; Diet; Disease Models, Animal; Do | 2021 |
Ibrutinib does not prevent kidney fibrosis following acute and chronic injury.
Topics: Acute Kidney Injury; Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; B | 2021 |
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Topics: Adenine; Animals; Epithelial-Mesenchymal Transition; Fibrosis; Galectin 3; Glycogen Synthase Kinase | 2021 |
Endothelin receptors in renal interstitial cells do not contribute to the development of fibrosis during experimental kidney disease.
Topics: Adenine; Animals; Fibrosis; Gene Deletion; Gene Expression Regulation; Kidney; Kidney Diseases; Mice | 2021 |
Erhuang Formula ameliorates renal damage in adenine-induced chronic renal failure rats via inhibiting inflammatory and fibrotic responses.
Topics: Adenine; Animals; Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Creatinine; Drugs, Chin | 2017 |
Human adipose derived stem cells regress fibrosis in a chronic renal fibrotic model induced by adenine.
Topics: Adenine; Adipose Tissue; Animals; Cells, Cultured; Fibrosis; Gene Expression Profiling; Humans; Kidn | 2017 |
RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Animals; ATP Citrate (pro-S)-Lyase; Cell Differentiation; D | 2018 |
Ameliorative effect of ursolic acid on renal fibrosis in adenine-induced chronic kidney disease in rats.
Topics: Adenine; Animals; Blood Urea Nitrogen; Collagen Type I; Connective Tissue Growth Factor; Creatinine; | 2018 |
Cellular Origin and Functional Relevance of Collagen I Production in the Kidney.
Topics: Acute Kidney Injury; Adenine; Animals; Bone Marrow Cells; Cell Lineage; Collagen Type I; Epithelial | 2018 |
Antioxidant N-acetylcysteine inhibits maladaptive myocyte autophagy in pressure overload induced cardiac remodeling in rats.
Topics: Acetylcysteine; Adaptation, Physiological; Adenine; Animals; Antioxidants; Autophagy; Blood Pressure | 2018 |
Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model.
Topics: Adenine; Animal Feed; Animals; Biomarkers; Dietary Supplements; Disease Models, Animal; Down-Regulat | 2018 |
The effect of sildenafil on rats with adenine-Induced chronic kidney disease.
Topics: Adenine; Animals; Biomarkers; Blood Pressure; Body Weight; Creatinine; Cytokines; Fibrosis; Inflamma | 2018 |
Pharmacological inhibition of autophagy by 3-MA attenuates hyperuricemic nephropathy.
Topics: Adenine; Animals; Autophagy; Autophagy-Related Proteins; Cell Line; Disease Models, Animal; Extracel | 2018 |
Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression.
Topics: Actins; Adenine; Animals; Cadherins; Creatinine; Diet; Disease Models, Animal; Extracellular Matrix; | 2019 |
Effects of lactulose on renal function and gut microbiota in adenine-induced chronic kidney disease rats.
Topics: Adenine; Animals; Bacteria; Biomarkers; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Dis | 2019 |
Towards minimally-invasive, quantitative assessment of chronic kidney disease using optical spectroscopy.
Topics: Adenine; Animals; Atrophy; Blood Urea Nitrogen; Diet; Disease Models, Animal; Female; Fibrosis; Kidn | 2019 |
Comparison of the Effects of Indobufen and Warfarin in a Rat Model of Adenine-Induced Chronic Kidney Disease.
Topics: Adenine; Animals; Anticoagulants; China; Disease Models, Animal; Fibrosis; Isoindoles; Kidney; Kidne | 2019 |
Ultra performance liquid chromatography-based metabonomic study of therapeutic effect of the surface layer of Poria cocos on adenine-induced chronic kidney disease provides new insight into anti-fibrosis mechanism.
Topics: Adenine; Animals; Biomarkers; Chromatography, High Pressure Liquid; Fibrosis; Male; Mass Spectrometr | 2013 |
NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Granuloma; Inflammation Mediators; Kidney; Male; | 2013 |
Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b.
Topics: 3' Untranslated Regions; Adenine; Animals; Apolipoproteins E; Binding Sites; Cell Line; Diabetic Nep | 2014 |
A 5-hydroxytryptamine receptor antagonist, sarpogrelate, reduces renal tubulointerstitial fibrosis by suppressing PAI-1.
Topics: Adenine; Animals; Cells, Cultured; Disease Models, Animal; Fatty Acid-Binding Proteins; Fibrosis; In | 2013 |
Chinese herbal medicine Shenqi Detoxification Granule inhibits fibrosis in adenine induced chronic renal failure rats.
Topics: Adenine; Albumins; Animals; Blood Urea Nitrogen; Cholesterol; Connective Tissue Growth Factor; Creat | 2014 |
Phosphate binders prevent phosphate-induced cellular senescence of vascular smooth muscle cells and vascular calcification in a modified, adenine-based uremic rat model.
Topics: Adenine; Animal Feed; Animals; Calcinosis; Calcium Carbonate; Cellular Senescence; Disease Models, A | 2015 |
Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts.
Topics: Adenine; Animals; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Cell Prolifer | 2015 |
Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Topics: Adenine; Adenocarcinoma; Animals; Antineoplastic Agents; Female; Fibrosis; Male; Mice; Mice, Inbred | 2015 |
Ameliorative effect of chrysin on adenine-induced chronic kidney disease in rats.
Topics: Acetylglucosaminidase; Adenine; Animals; Antioxidants; Creatinine; Disease Models, Animal; Fibrosis; | 2015 |
An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice.
Topics: Adenine; Adoptive Transfer; Animals; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Fibro | 2016 |
A highly reproducible mice model of chronic kidney disease: Evidences of behavioural abnormalities and blood-brain barrier disruption.
Topics: Adenine; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Creatinine; Diet; Disease Models, An | 2016 |
Naringin in Ganshuang Granule suppresses activation of hepatic stellate cells for anti-fibrosis effect by inhibition of mammalian target of rapamycin.
Topics: Adenine; Animals; Autophagy; Cells, Cultured; Drugs, Chinese Herbal; Fibrosis; Flavanones; Hepatic S | 2017 |
Valproic acid attenuates renal fibrosis through the induction of autophagy.
Topics: Actins; Adenine; Animals; Autophagy; Cell Line; Collagen Type I; Cytoprotection; Disease Models, Ani | 2017 |
Protease-activated receptor 2 exacerbates adenine-induced renal tubulointerstitial injury in mice.
Topics: Adenine; Animals; Enzyme-Linked Immunosorbent Assay; Factor V; Factor Xa; Fibrin; Fibrosis; Gene Exp | 2017 |
Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model.
Topics: Actins; Adenine; Animals; Chemokines; Chemotaxis; Collagen; Cytokines; Disease Models, Animal; Fibro | 2009 |
Effect of antiviral therapy on the immunohistochemical expression of bcl-xL and bax protein in patients with HBeAg-negative chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biopsy; Fema | 2011 |
Autophagy is increased in laminin α2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A.
Topics: Adenine; Animals; Apoptosis; Autophagy; Behavior, Animal; Disease Models, Animal; Drug Therapy, Comb | 2011 |
The role of autophagy in unilateral ureteral obstruction rat model.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Proliferation; Cytoprotection; Disease Models, Animal; | 2012 |
Chronic exposure to environmental contaminant nonylphenol exacerbates adenine-induced chronic renal insufficiency: role of signaling pathways and therapeutic impact of rosuvastatin.
Topics: Adenine; Animals; Biomarkers; Blood Urea Nitrogen; Body Weight; Creatinine; Cytoprotection; Disease | 2012 |
Application of faecal metabonomics on an experimental model of tubulointerstitial fibrosis by ultra performance liquid chromatography/high-sensitivity mass spectrometry with MS(E) data collection technique.
Topics: Adenine; Animals; Biomarkers; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; F | 2012 |
Intrarenal metabolomic investigation of chronic kidney disease and its TGF-β1 mechanism in induced-adenine rats using UPLC Q-TOF/HSMS/MS(E).
Topics: Adenine; Animals; Chromatography, High Pressure Liquid; Cresols; Fatty Acids, Unsaturated; Fibrosis; | 2013 |
Successful treatment of fibrosing cholestatic hepatitis using adefovir dipivoxil in a patient with cirrhosis and renal insufficiency.
Topics: Adenine; Adult; Antiviral Agents; Bacterial Infections; Cholestasis; Drug Resistance, Microbial; Fib | 2003 |
Congenital abnormalities of cranial nerve development: overview, molecular mechanisms, and further evidence of heterogeneity and complexity of syndromes with congenital limitation of eye movements.
Topics: Adenine; Adolescent; Adult; Amino Acid Substitution; Arginine; Child; Child, Preschool; Chromosome M | 2004 |
Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.
Topics: Adenine; Adenine Phosphoribosyltransferase; Alleles; Animals; Erythrocytes; Fibrosis; Homozygote; Hu | 1996 |
Chemokines, nitric oxide and antiarthritic effects of 9-(2-phosphonomethoxyethyl)adenine (Adefovir).
Topics: Adenine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemokine CCL5; | 1999 |
Animal model of adenine-induced chronic renal failure in rats.
Topics: Adenine; Amino Acids; Animals; Atrophy; Creatinine; Disease Models, Animal; Fibrosis; Guanidines; Ho | 1986 |