adenine has been researched along with Cardiotoxicity in 7 studies
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitoxantrone (MTX) is an antineoplastic agent used to treat several types of cancers and on multiple sclerosis, which shows a high incidence of cardiotoxicity." | 3.85 | Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy. ( Bastos, ML; Carvalho, F; Carvalho, RA; Costa, VM; Gomes, AS; Pinto, M; Reis-Mendes, A; Remião, F; Sousa, E, 2017) |
| "The increasing indications and addition of newer agents to clinical practice and emergence of BTK inhibitor-related cardiac adverse events have complicated the management decisions for utilization of this class of therapy." | 2.82 | Cardiotoxicity of BTK inhibitors: ibrutinib and beyond. ( Awan, FT; Christensen, BW; Zaha, VG, 2022) |
| " We also synopsize and discuss the cardiovascular adverse effects related to other more selective BTK inhibitors, which may guide the selection of appropriate BTK inhibitors." | 2.82 | Ibrutinib-Associated Cardiotoxicity: From the Pharmaceutical to the Clinical. ( Dong, R; Lin, N; Tan, B; Yan, Y; Zeng, X, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, BW | 1 |
| Zaha, VG | 1 |
| Awan, FT | 1 |
| Dong, R | 1 |
| Yan, Y | 1 |
| Zeng, X | 1 |
| Lin, N | 1 |
| Tan, B | 1 |
| Ratain, MJ | 1 |
| Moslehi, JJ | 1 |
| Lichter, AS | 1 |
| Sestier, M | 1 |
| Hillis, C | 1 |
| Fraser, G | 1 |
| Leong, D | 1 |
| Tang, CPS | 1 |
| McMullen, J | 1 |
| Tam, C | 1 |
| Shafaattalab, S | 1 |
| Lin, E | 1 |
| Christidi, E | 1 |
| Huang, H | 1 |
| Nartiss, Y | 1 |
| Garcia, A | 1 |
| Lee, J | 1 |
| Protze, S | 1 |
| Keller, G | 1 |
| Brunham, L | 1 |
| Tibbits, GF | 1 |
| Laksman, Z | 1 |
| Reis-Mendes, A | 1 |
| Gomes, AS | 1 |
| Carvalho, RA | 1 |
| Carvalho, F | 1 |
| Remião, F | 1 |
| Pinto, M | 1 |
| Bastos, ML | 1 |
| Sousa, E | 1 |
| Costa, VM | 1 |
4 reviews available for adenine and Cardiotoxicity
| Article | Year |
|---|---|
Cardiotoxicity of BTK inhibitors: ibrutinib and beyond.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Cardiotoxicity; Humans; Hypertension; Leukemia, Lympho | 2022 |
Ibrutinib-Associated Cardiotoxicity: From the Pharmaceutical to the Clinical.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Cardiotoxicity; Humans; Leukemia, Lymphocytic, Chronic | 2022 |
Bruton's tyrosine kinase Inhibitors and Cardiotoxicity: More Than Just Atrial Fibrillation.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Atrial Fibrillation; Cardiotoxicity; Heart Failure; He | 2021 |
Cardiac side effects of bruton tyrosine kinase (BTK) inhibitors.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Anticoagulants; Antineoplastic Agents; Atrial Fibrilla | 2018 |
3 other studies available for adenine and Cardiotoxicity
| Article | Year |
|---|---|
Ibrutinib's Cardiotoxicity-An Opportunity for Postmarketing Regulation.
Topics: Adenine; Cardiotoxicity; Humans; Piperidines | 2021 |
Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes.
Topics: Adenine; Atrial Fibrillation; Cardiotoxicity; Cell Differentiation; Cells, Cultured; Heart; Heart At | 2019 |
Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy.
Topics: Adenine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Autophagy; Cardiotoxicity; Cell Lin | 2017 |