Page last updated: 2024-10-16

adenine and Carcinoma

adenine has been researched along with Carcinoma in 37 studies

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"To explore the effects of 3-methyladenine (3-MA, an autophagy inhibitor) on sensitivities of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy and the underlying mechanisms."7.83[Autophagy inhibitor 3-methyladenine enhances the sensitivity of nasopharyngeal carcinoma cells to chemotherapy and radiotherapy]. ( Chen, G; Huang, Y; Jiang, C; Liu, H; Ma, L; Song, L; Sun, X, 2016)
" Wogonin, a flavonoid compound derived from the traditional Chinese medicine of Huang-Qin, has anticancer activity in many cancer cells including human nasopharyngeal carcinoma (NPC)."7.78Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. ( Chen, YW; Chow, SE; Huang, YK; Liang, CA; Wang, JS, 2012)
"To explore the effects of 3-methyladenine (3-MA, an autophagy inhibitor) on sensitivities of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy and the underlying mechanisms."3.83[Autophagy inhibitor 3-methyladenine enhances the sensitivity of nasopharyngeal carcinoma cells to chemotherapy and radiotherapy]. ( Chen, G; Huang, Y; Jiang, C; Liu, H; Ma, L; Song, L; Sun, X, 2016)
" Wogonin, a flavonoid compound derived from the traditional Chinese medicine of Huang-Qin, has anticancer activity in many cancer cells including human nasopharyngeal carcinoma (NPC)."3.78Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. ( Chen, YW; Chow, SE; Huang, YK; Liang, CA; Wang, JS, 2012)
"14C-Adenine was found to be incorporated into nucleic acid bases of bladder carcinoma cells."1.26Nucleic acid metabolism of bladder carcinoma cells in vitro. ( Ishii, Y; Koiso, K; Niijima, T, 1982)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199021 (56.76)18.7374
1990's6 (16.22)18.2507
2000's4 (10.81)29.6817
2010's6 (16.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, Y1
Yin, W1
Zhu, X1
Liu, Z1
Liu, J1
Li, L1
Nie, D1
Tao, Q1
Wu, J1
Fan, J1
Lin, C1
Zhao, S1
Ju, D1
Song, L1
Ma, L1
Chen, G1
Huang, Y1
Sun, X1
Jiang, C1
Liu, H1
Mane, RS1
Ghosh, S1
Chopade, BA1
Reiser, O1
Dhavale, DD1
Zulhabri, O1
Rahman, J1
Ismail, S1
Isa, MR1
Wan Zurinah, WN1
Chow, SE1
Chen, YW1
Liang, CA1
Huang, YK1
Wang, JS1
FJELDE, A2
YANASE, T1
KASAI, A1
YAMANAKA, J1
BALIS, ME1
PECORA, P1
SALSER, JS1
KLENOW, H1
OVERGAARD-HANSEN, K2
FREDERIKSEN, S1
HENDERSON, JF2
KHOO, MK2
UPPIN, BI1
SCHOLEFIELD, PG1
LETNANSKY, K1
Inoue, H1
Nonomura, N1
Kojima, Y1
Shiba, M1
Oka, D1
Arai, Y1
Nakayama, M1
Takayama, H1
Nishimura, K1
Mori, H1
Okuyama, A1
Li, AJ1
Scoles, DR1
Armstrong, KU1
Karlan, BY1
Watanabe, SM1
Goodman, MF1
Koiso, K1
Ishii, Y1
Niijima, T1
Otová, B1
Krenová, D1
Zídek, Z1
Holý, A1
Votruba, I1
Kren, V1
Marschke, RF1
Wieand, HS1
O'Connell, MJ1
Rubin, J1
Schutt, AJ1
Burch, PA1
Kovach, JS1
Asbury, RF1
Blessing, JA2
Look, KY2
Clarke-Pearson, D1
Homesley, HD1
Terunuma, H1
Hayakashi, T1
Tsuneyoshi, T1
Fujita, M1
Kino, I1
Baba, S1
Asbury, R1
Buller, R1
Lucci, JA1
Marko, D1
Romanakis, K1
Zankl, H1
Fürstenberger, G1
Steinbauer, B1
Eisenbrand, G1
Esteller, M1
Toyota, M1
Sanchez-Cespedes, M1
Capella, G1
Peinado, MA1
Watkins, DN1
Issa, JP1
Sidransky, D1
Baylin, SB1
Herman, JG1
Murono, S1
Raab-Traub, N1
Pagano, JS1
Karuzina, NP1
Shuvaeva, NI1
Klimanova, ZF1
Antoshechkina, ET1
DeRubertis, F1
Yamashita, K1
Dekker, A1
Larsen, PR1
Field, JB1
Hampar, B1
Derge, JG1
Martos, LM1
Tagamets, MA1
Burroughs, MA1
Miyai, K1
Allen, LB1
Huffman, JH1
Sidwell, RW1
Tolman, RL1
Taylor, JM1
Lembach, KJ1
Schwartz, PM1
Shipman, C1
Carlson, RH1
Drach, JC1
Richards, EG1
Wheeler, GP1
Alexander, JA1
Willoughby, HW1
Maughan, GB1
Tremblay, PC1
Wood, N1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Combination in Microsatellite Stable (MSS), MGMT Silenced Metastatic Colorectal Cancer (mCRC): the MAYA Study[NCT03832621]Phase 2135 participants (Actual)Interventional2019-03-25Completed
Multicenter Phase II Study of Preoperative Chemoradiotherapy With CApecitabine Plus Temozolomide in Patients With MGMT Silenced and Microsatellite Stable Locally Advanced RecTal Cancer: the CATARTIC Trial[NCT05136326]Phase 221 participants (Anticipated)Interventional2021-12-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for adenine and Carcinoma

ArticleYear
Advanced colorectal adenocarcinoma: treatment with amonafide.
    Journal of the National Cancer Institute, 1994, Jun-15, Volume: 86, Issue:12

    Topics: Adenine; Antineoplastic Agents; Carcinoma; Colorectal Neoplasms; Humans; Imides; Intercalating Agent

1994
A Gynecologic Oncology Group phase II study of amonafide (NSC 308847) in epithelial ovarian cancer.
    American journal of clinical oncology, 1993, Volume: 16, Issue:6

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Carcinoma; Female; Humans; Imides; Isoquinolines; Middl

1993
A phase II trial of amonafide in patients with nonsquamous cell carcinoma of the cervix. A Gynecologic Oncology Group study.
    American journal of clinical oncology, 1997, Volume: 20, Issue:6

    Topics: Adenine; Adult; Antineoplastic Agents; Carcinoma; Female; Humans; Imides; Isoquinolines; Middle Aged

1997

Other Studies

34 other studies available for adenine and Carcinoma

ArticleYear
Blocked autophagy enhances radiosensitivity of nasopharyngeal carcinoma cell line CNE-2 in vitro.
    Acta oto-laryngologica, 2014, Volume: 134, Issue:1

    Topics: Adenine; Autophagy; Carcinoma; Cell Line, Tumor; Cell Survival; Humans; Nasopharyngeal Carcinoma; Na

2014
Inhibition of Autophagy Potentiated the Antitumor Effect of Nedaplatin in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Butadienes; Carcinoma; Cell Line, Tumor; Cell

2015
[Autophagy inhibitor 3-methyladenine enhances the sensitivity of nasopharyngeal carcinoma cells to chemotherapy and radiotherapy].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2016, Volume: 41, Issue:1

    Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma; Cell Line, Tumor;

2016
Synthesis of an adenine nucleoside containing the (8'R) epimeric carbohydrate core of amipurimycin and its biological study.
    The Journal of organic chemistry, 2011, Apr-15, Volume: 76, Issue:8

    Topics: Acids; Adenine; Antifungal Agents; Antineoplastic Agents; Carcinoma; Catalysis; Cell Proliferation;

2011
Predominance of G to A codon 12 mutation K-ras gene in Dukes' B colorectal cancer.
    Singapore medical journal, 2012, Volume: 53, Issue:1

    Topics: Adenine; Adenoma; Adult; Aged; Aged, 80 and over; Aspartic Acid; Carcinoma; Codon; Colorectal Neopla

2012
Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:11

    Topics: Adenine; Apoptosis; Autophagy; Carcinoma; Cell Line, Tumor; Drugs, Chinese Herbal; Extracellular Sig

2012
The effect of two purine analogs on a human tumor in tissue culture.
    Zeitschrift fur Krebsforschung, 1956, Volume: 61, Issue:4

    Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop

1956
The effect of two purine analogs on a human tumor in tissue culture.
    Zeitschrift fur Krebsforschung, 1956, Volume: 61, Issue:4

    Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop

1956
The effect of two purine analogs on a human tumor in tissue culture.
    Zeitschrift fur Krebsforschung, 1956, Volume: 61, Issue:4

    Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop

1956
The effect of two purine analogs on a human tumor in tissue culture.
    Zeitschrift fur Krebsforschung, 1956, Volume: 61, Issue:4

    Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop

1956
[Clinical experiences with adociron in the treatment of radioleukopenia in carcinoma of the cervix].
    [Sanfujinka no shinpo] Advances in obstetrics and gynecology, 1962, Volume: 14

    Topics: Adenine; Carcinoma; Female; Humans; Leukocyte Disorders; Leukopenia; Radiation Injuries; Radiotherap

1962
STUDIES OF COMPOUNDS THAT INHIBIT CELL GROWTH.
    Experimental cell research, 1963, Volume: 24

    Topics: Acridines; Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Liver

1963
EFFECT OF CORDYCEPIN TRIPHOSPHATE ON THE INCORPORATION OF (8-14C)ADENINE AND (32P)
    Biochimica et biophysica acta, 1964, Mar-23, Volume: 80

    Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Chromat

1964
THE INHIBITION OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE FORMATION BY CORDYCEPIN TRIPHOSPHATE IN EXTRACTS OF EHRLICH ASCITES TUMOR CELLS.
    Biochimica et biophysica acta, 1964, Mar-23, Volume: 80

    Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrli

1964
DEOXYRIBOSYL-8-AZAADENINE. ITS DEAMINATION TO DEOXYRIBOSYL-8-AZAHYPOXANTHINE AND EFFECT ON NUCLEIC ACID SYNTHESIS IN EHRLICH ASCITES CELLS IN VITRO.
    Biochimica et biophysica acta, 1964, Aug-12, Volume: 87

    Topics: Adenine; Aminohydrolases; Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Deamination; DNA; D

1964
SYNTHESIS OF 5-PHOSPHORIBOSYL 1-PYROPHOSPHATE FROM GLUCOSE IN EHRLICH ASCITES TUMOR CELLS IN VITRO.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Adenine; Adenine Nucleotides; Animals; Carbohydrate Metabolism; Carcinoma; Carcinoma, Ehrlich Tumor;

1965
AVAILABILITY OF 5-PHOSPHORIBOSYL 1-PYROPHOSPHATE FOR RIBONUCLEOTIDE SYNTHESIS IN EHRLICH ASCITES TUMOR CELLS IN VITRO.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Dinitrophenols; Diphosphates; Guanine; In Vit

1965
STUDIES OF THE BIOSYNTHESIS OF NUCLEOTIDES IN EHRLICH ASCITES CARCINOMA CELLS IN VITRO.
    Canadian journal of biochemistry, 1965, Volume: 43

    Topics: Adenine; Animals; Ascites; Carbohydrate Metabolism; Carbon Dioxide; Carcinoma; Carcinoma, Ehrlich Tu

1965
[THE INFLUENCE OF GLUCOSE ON THE PHOSPHORYLATION OF 2-DEOXY-D-GLUCOSE AND THE ADENINE NUCLEOTIDE COMPOSITION OF EHRLICH ASCITES CARCINOMA CELLS].
    Biochemische Zeitschrift, 1964, Dec-07, Volume: 341

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Ascites; Carbohydrate Metabolism; Car

1964
Somatic mutations of the von Hippel-Lindau disease gene in renal carcinomas occurring in patients with long-term dialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:7

    Topics: Adenine; Aged; Base Sequence; Carcinoma; Carcinoma, Renal Cell; Gene Deletion; Guanine; Humans; Kidn

2007
Androgen receptor cytosine-adenine-guanine repeat polymorphisms modulate EGFR signaling in epithelial ovarian carcinomas.
    Gynecologic oncology, 2008, Volume: 109, Issue:2

    Topics: Adenine; Alleles; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytosine; ErbB Receptors; Female;

2008
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:5

    Topics: 2-Aminopurine; Adenine; Animals; Base Composition; Carcinoma; Cattle; Cell Line; Cytosine; DNA; DNA

1981
Nucleic acid metabolism of bladder carcinoma cells in vitro.
    Urological research, 1982, Volume: 10, Issue:2

    Topics: Adenine; Adult; Aged; Base Composition; Carbon Radioisotopes; Carcinoma; Cells, Cultured; DNA, Neopl

1982
Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). III. Rat and mouse carcinomas and sarcomas.
    Folia biologica, 1993, Volume: 39, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; Carcinoma; Female; Mice; Mice, Inbred C57BL; Organophosphonates;

1993
Mutational heterogeneity among individual tumors in a case of multiple primary malignancy of the colon.
    Japanese journal of clinical oncology, 1993, Volume: 23, Issue:6

    Topics: Adenine; Adenocarcinoma; Adenoma; Aged; Alleles; Base Sequence; Carcinoma; Codon; Colonic Neoplasms;

1993
Induction of apoptosis by an inhibitor of cAMP-specific PDE in malignant murine carcinoma cells overexpressing PDE activity in comparison to their nonmalignant counterparts.
    Cell biochemistry and biophysics, 1998, Volume: 28, Issue:2-3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Animals; Carcinoma; Cell Cycle; Cell Division; Cell Si

1998
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Cancer research, 2000, May-01, Volume: 60, Issue:9

    Topics: Adenine; Adenoma; Carcinoma; Colorectal Neoplasms; DNA Methylation; Gene Silencing; Genes, p53; Gene

2000
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Cancer research, 2000, May-01, Volume: 60, Issue:9

    Topics: Adenine; Adenoma; Carcinoma; Colorectal Neoplasms; DNA Methylation; Gene Silencing; Genes, p53; Gene

2000
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Cancer research, 2000, May-01, Volume: 60, Issue:9

    Topics: Adenine; Adenoma; Carcinoma; Colorectal Neoplasms; DNA Methylation; Gene Silencing; Genes, p53; Gene

2000
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Cancer research, 2000, May-01, Volume: 60, Issue:9

    Topics: Adenine; Adenoma; Carcinoma; Colorectal Neoplasms; DNA Methylation; Gene Silencing; Genes, p53; Gene

2000
Prevention and inhibition of nasopharyngeal carcinoma growth by antiviral phosphonated nucleoside analogs.
    Cancer research, 2001, Nov-01, Volume: 61, Issue:21

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Division; Cidofovir; Cytosine; E

2001
[Individual sensitivity of ovarian ascitic cancer to thiophosphamide].
    Voprosy onkologii, 1974, Volume: 20, Issue:8

    Topics: Adenine; Adenocarcinoma; Ascites; Ascitic Fluid; Carbon Radioisotopes; Carcinoma; Carcinoma, Papilla

1974
Effects of thyroid-stimulating hormone on adenyl cyclase activity and intermediary metabolism of "cold" thyroid nodules and normal human thyroid tissue.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:5

    Topics: Adenine; Adenoma; Adenylyl Cyclases; Adult; Carbon Dioxide; Carbon Isotopes; Carcinoma; Cyclic AMP;

1972
Sequence of spontaneous Epstein-Barr virus activation and selective DNA synthesis in activated cells in the presence of hydroxyurea.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:9

    Topics: Adenine; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Isotopes; Carcinoma; Cell Line;

1972
Synthesis and anti-deoxyribonucleic acid virus activity of certain 9-beta-D-arabinofuranosyl-2-substituted adenine derivatives.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:2

    Topics: Adenine; Adenoviridae; Animals; Arabinose; Carcinoma; Cell Line; Cricetinae; Cytopathogenic Effect,

1974
Reversible inhibition of cell multiplication in vitro by inhibitors of arginine esteroproteases.
    Biochimica et biophysica acta, 1973, Nov-02, Volume: 329, Issue:1

    Topics: Adenine; Amidines; Aniline Compounds; Animals; Arginine; Benzene Derivatives; Carcinoma; Cell Divisi

1973
Thermal inactivation as a means of inhibiting the serum-associated deamination of 9-beta-D Arabinofuranosyladenine in tissue culture media.
    Antimicrobial agents and chemotherapy, 1974, Volume: 5, Issue:3

    Topics: Adenine; Aminohydrolases; Arabinose; Carcinoma; Cell Line; Cells, Cultured; Culture Media; Deaminati

1974
5S RNA. An analysis of possible base pairing schemes.
    European journal of biochemistry, 1969, Volume: 10, Issue:1

    Topics: Adenine; Carcinoma; Cell Line; Chemical Phenomena; Chemistry; Computers; Cytosine; Escherichia coli;

1969
Metabolic activities of murine carcinoma 755 at various stages of growth.
    Cancer research, 1972, Volume: 32, Issue:8

    Topics: Adenine; Animals; Autoradiography; Carbon Isotopes; Carcinoma; Cell-Free System; Chromatography, Pap

1972
Determination of individual human tumour sensitivity to antitumour agents by tissue-slice incubation.
    Canadian journal of surgery. Journal canadien de chirurgie, 1971, Volume: 14, Issue:6

    Topics: Adenine; Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma; Colonic Neoplasms; Cultu

1971