Page last updated: 2024-10-16

adenine and Cancer of the Retina

adenine has been researched along with Cancer of the Retina in 3 studies

Research Excerpts

ExcerptRelevanceReference
"To study the inhibition of retinoblastoma cell viability by two commonly used autophagy inhibitors, chloroquine (CQ) and 3-methyladenine (3-MA), alone or in combination with the conventional chemotherapeutic drug vincristine (VCR), and to investigate whether the mechanisms of these drugs are related to inhibition of autophagy."7.81Low concentrations of chloroquine and 3-methyladenine suppress the viability of retinoblastoma cells synergistically with vincristine independent of autophagy inhibition. ( Chen, X; Chen, YH; Jiang, PF; Li, LJ; Li, W; Shen, HQ; Zheng, XY, 2015)
"To study the inhibition of retinoblastoma cell viability by two commonly used autophagy inhibitors, chloroquine (CQ) and 3-methyladenine (3-MA), alone or in combination with the conventional chemotherapeutic drug vincristine (VCR), and to investigate whether the mechanisms of these drugs are related to inhibition of autophagy."3.81Low concentrations of chloroquine and 3-methyladenine suppress the viability of retinoblastoma cells synergistically with vincristine independent of autophagy inhibition. ( Chen, X; Chen, YH; Jiang, PF; Li, LJ; Li, W; Shen, HQ; Zheng, XY, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Mathai, M1
Fein, JG1
Soussain, C1
Choquet, S1
Blonski, M1
Leclercq, D1
Houillier, C1
Rezai, K1
Bijou, F1
Houot, R1
Boyle, E1
Gressin, R1
Nicolas-Virelizier, E1
Barrie, M1
Moluçon-Chabrot, C1
Lelez, ML1
Clavert, A1
Coisy, S1
Leruez, S1
Touitou, V1
Cassoux, N1
Daniau, M1
Ertault de la Bretonnière, M1
El Yamani, A1
Ghesquières, H1
Hoang-Xuan, K1
Zheng, XY1
Li, LJ1
Li, W1
Jiang, PF1
Shen, HQ1
Chen, YH1
Chen, X1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Ibrutinib in Patients With Relapsed or Refractory Primary Central Nervous Lymphoma or Intraocular Lymphoma[NCT02542514]Phase 252 participants (Actual)Interventional2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for adenine and Cancer of the Retina

ArticleYear
Ibrutinib monotherapy for relapse or refractory primary CNS lymphoma and primary vitreoretinal lymphoma: Final analysis of the phase II 'proof-of-concept' iLOC study by the Lymphoma study association (LYSA) and the French oculo-cerebral lymphoma (LOC) net
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 117

    Topics: Adenine; Aged; Aged, 80 and over; Central Nervous System Neoplasms; Drug Resistance, Neoplasm; Femal

2019

Other Studies

2 other studies available for adenine and Cancer of the Retina

ArticleYear
Rapid Resolution of Presumed Vitreoretinal Lymphoma With Systemic Ibrutinib Therapy.
    Ophthalmic surgery, lasers & imaging retina, 2021, Volume: 52, Issue:4

    Topics: Adenine; Eye Neoplasms; Humans; Lymphoma, Large B-Cell, Diffuse; Piperidines; Retinal Neoplasms; Vit

2021
Low concentrations of chloroquine and 3-methyladenine suppress the viability of retinoblastoma cells synergistically with vincristine independent of autophagy inhibition.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2015, Volume: 253, Issue:12

    Topics: Adenine; Antineoplastic Agents, Phytogenic; Antirheumatic Agents; Apoptosis; Autophagy; Blotting, We

2015