adenine has been researched along with Cancer of Stomach in 21 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve patients with recurrent, metastatic, or inoperable gastric adenocarcinoma were enrolled in an Illinois Cancer Center phase II trial of amonafide (nafidimide), a novel compound that acts as a DNA intercalator." | 9.07 | Phase II study of amonafide in gastric adenocarcinoma. An Illinois Cancer Center trial. ( Bauman, A; Benson, AB; Blough, RR; Carroll, RB; French, SL; Kilton, LJ; Mullane, MR; Schilsky, RL; Wade, JL, 1994) |
| "Twelve patients with recurrent, metastatic, or inoperable gastric adenocarcinoma were enrolled in an Illinois Cancer Center phase II trial of amonafide (nafidimide), a novel compound that acts as a DNA intercalator." | 5.07 | Phase II study of amonafide in gastric adenocarcinoma. An Illinois Cancer Center trial. ( Bauman, A; Benson, AB; Blough, RR; Carroll, RB; French, SL; Kilton, LJ; Mullane, MR; Schilsky, RL; Wade, JL, 1994) |
| " We found that in a gastric adenocarcinoma cell line GTL-16, where MET activity is deregulated due to receptor overexpression, two different MET inhibitors PHA665752 and EMD1214063 lead to cell death paralleled by the induction of autophagy." | 3.79 | Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells. ( Aebersold, DM; Bladt, F; Blaukat, A; Fey, MF; Humbert, M; Medová, M; Tschan, MP; Zimmer, Y, 2013) |
| "Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans." | 1.51 | Inhibition of autophagy enhances cinobufagin‑induced apoptosis in gastric cancer. ( Guo, H; Li, X; Lu, B; Tian, Q; Wang, Y; Wu, M; Xiong, X; Zhang, H; Zhang, Q; Zhou, T, 2019) |
| "In addition, curcumin treatment induced gastric cancer cell apoptosis in a dose‑responsive manner." | 1.46 | Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells. ( Li, H; Li, W; Yang, J; Zhang, H; Zheng, P; Zhou, Y, 2017) |
| "Gastric cancer is difficult to cure due to its clinical heterogeneity and the complexity of its molecular mechanisms." | 1.46 | Inhibition of cell proliferation and induction of autophagy by KDM2B/FBXL10 knockdown in gastric cancer cells. ( Cui, H; Hou, J; Huang, M; Jiang, X; Tang, C; Wang, F; Weng, X; Zhang, D; Zhao, E; Zhong, X, 2017) |
| "Amonafide is a DNA intercalator in clinical development for the treatment of cancer." | 1.37 | Methoxyethylamino-numonafide is an efficacious and minimally toxic amonafide derivative in murine models of human cancer. ( Appella, DH; Chen, Z; Huang, S; Liu, Y; Lou, G; Norton, JT; Wang, C; Witschi, MA; Xu, Q, 2011) |
| "Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor beta type II receptor (TbetaR-II) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis." | 1.29 | Mutations of the transforming growth factor beta type II receptor gene and microsatellite instability in gastric cancer. ( Izawa, H; Kawabata, Y; Miyoshi, Y; Monden, M; Monden, T; Nishisho, I; Ohnishi, T; Ohue, M; Sasaki, M; Sekimoto, M; Shiozaki, H; Tomita, N, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, W | 1 |
| Zhou, Y | 1 |
| Yang, J | 1 |
| Li, H | 1 |
| Zhang, H | 2 |
| Zheng, P | 1 |
| Zhao, E | 1 |
| Tang, C | 1 |
| Jiang, X | 1 |
| Weng, X | 1 |
| Zhong, X | 1 |
| Zhang, D | 1 |
| Hou, J | 1 |
| Wang, F | 2 |
| Huang, M | 1 |
| Cui, H | 1 |
| Zhao, HG | 1 |
| Zhou, SL | 1 |
| Lin, YY | 1 |
| Wang, H | 1 |
| Dai, HF | 1 |
| Huang, FY | 1 |
| Xiong, X | 1 |
| Lu, B | 1 |
| Tian, Q | 1 |
| Wu, M | 1 |
| Guo, H | 1 |
| Zhang, Q | 2 |
| Li, X | 1 |
| Zhou, T | 1 |
| Wang, Y | 1 |
| Li, Y | 1 |
| Zhang, J | 1 |
| Ma, H | 1 |
| Chen, X | 1 |
| Liu, T | 1 |
| Jiao, Z | 1 |
| He, W | 1 |
| Liu, X | 1 |
| Zeng, X | 1 |
| Li, Z | 1 |
| Wang, JW | 1 |
| Wang, WZ | 1 |
| Zhi, XF | 1 |
| Li, BW | 1 |
| Wang, LJ | 1 |
| Xie, KL | 1 |
| Tao, JQ | 1 |
| Tang, J | 1 |
| Wei, S | 1 |
| Zhu, Y | 1 |
| Xu, H | 1 |
| Zhang, DC | 1 |
| Yang, L | 2 |
| Xu, ZK | 1 |
| Yan, L | 1 |
| Yanan, D | 1 |
| Donglan, S | 1 |
| Na, W | 1 |
| Rongmiao, Z | 1 |
| Zhifeng, C | 1 |
| Liu, Y | 1 |
| Norton, JT | 1 |
| Witschi, MA | 1 |
| Xu, Q | 1 |
| Lou, G | 1 |
| Wang, C | 1 |
| Appella, DH | 1 |
| Chen, Z | 1 |
| Huang, S | 1 |
| Humbert, M | 1 |
| Medová, M | 1 |
| Aebersold, DM | 1 |
| Blaukat, A | 1 |
| Bladt, F | 1 |
| Fey, MF | 1 |
| Zimmer, Y | 1 |
| Tschan, MP | 1 |
| Saitoh, M | 1 |
| Nagai, K | 1 |
| Nakagawa, K | 1 |
| Yamamura, T | 1 |
| Yamamoto, S | 1 |
| Nishizaki, T | 1 |
| Liedert, B | 1 |
| Pluim, D | 1 |
| Schellens, J | 1 |
| Thomale, J | 1 |
| Zhu, H | 1 |
| Zhou, B | 1 |
| Yu, R | 1 |
| Tang, N | 1 |
| Wang, B | 1 |
| Mullane, MR | 1 |
| Schilsky, RL | 1 |
| Carroll, RB | 1 |
| Wade, JL | 1 |
| Kilton, LJ | 1 |
| Blough, RR | 1 |
| Bauman, A | 1 |
| French, SL | 1 |
| Benson, AB | 1 |
| Wishnok, JS | 3 |
| Tannenbaum, SR | 3 |
| Stillwell, WG | 3 |
| Glogowski, JA | 1 |
| Leaf, CD | 1 |
| Kodama, E | 1 |
| Shigeta, S | 1 |
| Suzuki, T | 1 |
| De Clercq, E | 1 |
| Ohue, M | 1 |
| Tomita, N | 1 |
| Monden, T | 1 |
| Miyoshi, Y | 1 |
| Ohnishi, T | 1 |
| Izawa, H | 1 |
| Kawabata, Y | 1 |
| Sasaki, M | 1 |
| Sekimoto, M | 1 |
| Nishisho, I | 1 |
| Shiozaki, H | 1 |
| Monden, M | 1 |
| Fisher, MJ | 1 |
| Virmani, AK | 1 |
| Wu, L | 1 |
| Aplenc, R | 1 |
| Harper, JC | 1 |
| Powell, SM | 1 |
| Rebbeck, TR | 1 |
| Sidransky, D | 1 |
| Gazdar, AF | 1 |
| El-Deiry, WS | 1 |
| Xu, HX | 2 |
| Glogowski, J | 2 |
| Correa, P | 2 |
| Zavala, D | 1 |
| Montes, G | 1 |
| Bartsch, H | 1 |
| Ohshima, H | 1 |
| Shuker, DE | 1 |
| Pignatelli, B | 1 |
| Calmels, S | 1 |
| Karuzina, NP | 1 |
| Timofeevskaia, EA | 1 |
2 reviews available for adenine and Cancer of Stomach
| Article | Year |
|---|---|
Urinary markers for exposures to alkylating or nitrosating agents.
Topics: Adenine; Alkylating Agents; Animals; Biomarkers; Dimethylnitrosamine; DNA Damage; Humans; Nitric Oxi | 1993 |
Exposure of humans to endogenous N-nitroso compounds: implications in cancer etiology.
Topics: Adenine; Bacterial Infections; Esophageal Neoplasms; Gastric Mucosa; Humans; Kinetics; Methylation; | 1990 |
1 trial available for adenine and Cancer of Stomach
| Article | Year |
|---|---|
Phase II study of amonafide in gastric adenocarcinoma. An Illinois Cancer Center trial.
Topics: Adenine; Adenocarcinoma; Antineoplastic Agents; Female; Hematologic Diseases; Humans; Imides; Isoqui | 1994 |
18 other studies available for adenine and Cancer of Stomach
| Article | Year |
|---|---|
Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells.
Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cell Line, Tumor; Curcumin; Gene Expre | 2017 |
Inhibition of cell proliferation and induction of autophagy by KDM2B/FBXL10 knockdown in gastric cancer cells.
Topics: Adenine; Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Extracellular Signal-Regulated MA | 2017 |
Autophagy plays a protective role against apoptosis induced by toxicarioside N via the Akt/mTOR pathway in human gastric cancer SGC-7901 cells.
Topics: Adenine; Apoptosis; Autophagy; Cell Line, Tumor; Cytoprotection; Glycosides; Humans; Proto-Oncogene | 2018 |
Inhibition of autophagy enhances cinobufagin‑induced apoptosis in gastric cancer.
Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; A | 2019 |
Protective role of autophagy in matrine‑induced gastric cancer cell death.
Topics: Adenine; Alkaloids; Apoptosis; Autophagy; Cell Line, Tumor; Cell Nucleus; Cell Shape; Cell Survival; | 2013 |
Natriuretic peptide receptor A inhibition suppresses gastric cancer development through reactive oxygen species-mediated G2/M cell cycle arrest and cell death.
Topics: Acetylcysteine; Adenine; Animals; Anthracenes; Atrial Natriuretic Factor; Autophagy; Cell Line, Tumo | 2016 |
Polymorphisms of XRCC1 gene and risk of gastric cardiac adenocarcinoma.
Topics: Adenine; Adenocarcinoma; Adult; Aged; Arginine; Cardia; Case-Control Studies; Codon; Cytosine; DNA R | 2009 |
Methoxyethylamino-numonafide is an efficacious and minimally toxic amonafide derivative in murine models of human cancer.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line; Disease Models, Animal; Gene Expression Profilin | 2011 |
Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.
Topics: Adenine; Adenocarcinoma; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cell Survival; Dr | 2013 |
Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.
Topics: Adenine; Adenosine; Adenylate Kinase; Aminoimidazole Carboxamide; Apoptosis; Caspase Inhibitors; Dip | 2004 |
Adduct-specific monoclonal antibodies for the measurement of cisplatin-induced DNA lesions in individual cell nuclei.
Topics: Adenine; Animals; Antibodies, Monoclonal; Antibody Specificity; Antineoplastic Agents; Cell Nucleus; | 2006 |
Myeloperoxidase G-463A polymorphism and the risk of gastric cancer: a case-control study.
Topics: Adenine; Adult; Case-Control Studies; China; Female; Guanine; Humans; Incidence; Male; Middle Aged; | 2006 |
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; F | 1996 |
Mutations of the transforming growth factor beta type II receptor gene and microsatellite instability in gastric cancer.
Topics: Adenine; DNA Mutational Analysis; DNA, Neoplasm; Female; Frameshift Mutation; Humans; Male; Microsat | 1996 |
Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer.
Topics: Adenine; Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Amino Acid Sequence; | 2001 |
Comparison of urinary nitrate, N-nitrosoproline, 7-methylguanine and 3-methyladenine levels in a human population at risk for gastric cancer.
Topics: Adenine; Guanine; Humans; Nitrates; Nitrosamines; Risk; Stomach Neoplasms | 1991 |
Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine, and 7-methylguanine in a Colombian population at high risk for stomach cancer.
Topics: Adenine; Colombia; Guanine; Humans; Nitrates; Nitrosamines; Regression Analysis; Risk Factors; Stoma | 1991 |
[The effect of sarcolysin on nucleic acid synthesis in monolayer cultures of human tumor cells].
Topics: Adenine; Carbon Isotopes; Culture Techniques; Female; Hemangiosarcoma; Humans; Lysine; Melphalan; Me | 1970 |