Compounds > adenine
Page last updated: 2024-10-16

adenine and Breast Cancer

adenine has been researched along with Breast Cancer in 75 studies

Research Excerpts

ExcerptRelevanceReference
"Twenty-eight patients with advanced breast cancer refractory to prior hormone and/or first-line chemotherapy (with or without anthracycline drugs) were treated with the investigational agent amonafide at a dose of 800 mg/m2 intravenously over 3 hours repeated every 4 weeks."9.07Phase II study of amonafide in advanced breast cancer. ( Depisch, D; Dittrich, C; Gisslinger, H; Haider, K; Kornek, G; Linkesch, W; Scheithauer, W, 1991)
"In a phase II study, 32 patients with advanced breast cancer previously unexposed to palliative cytotoxic chemotherapy were treated with amonafide, 800-900 mg intravenously over 3 h repeated every 4 weeks."9.07Amonafide as first-line chemotherapy for metastatic breast cancer. ( Depisch, D; Dittrich, C; Fazeny, B; Haider, K; Kornek, G; Raderer, M; Scheithauer, W, 1994)
" In this study, we reported that cyclovirobuxine D (CVB-D), an alkaloid component in a traditional Chinese herb, could induce autophagy in the MCF-7 human breast cancer cell line."7.80Cyclovirobuxine D induces autophagy-associated cell death via the Akt/mTOR pathway in MCF-7 human breast cancer cells. ( Gao, S; Gao, Y; Liu, P; Lu, J; Sun, D; Ye, J, 2014)
" In this study, we investigated the anticancer effects of sirtinol, a SIRT inhibitor, on MCF-7 human breast cancer cells."7.78Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells. ( Ahn, MY; Choi, WS; Jung, JH; Kim, HS; Kim, TH; Lee, BM; Lee, J; Wang, J; Yoon, KS; Yoon, S, 2012)
"In this study we have examined the cytotoxic effects of different concentrations of adenosine (Ado) and deoxyadenosine (dAdo) on human breast cancer cell lines."7.73Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway. ( Ghavami, S; Hashemi, M; Karami-Tehrani, F; Los, M; Maddika, S, 2005)
"Amonafide was chosen for inclusion in the Cancer and Leukemia Group B (CALGB) master metastatic breast cancer protocol."6.68Amonafide: An active agent in the treatment of previously untreated advanced breast cancer--a cancer and leukemia group B study (CALGB 8642). ( Berkowitz, I; Berry, D; Costanza, ME; Duggan, D; Henderson, IC; Kalra, J; Lyss, AP; Ratain, MJ; Shapiro, C; Wu, K, 1995)
"HER2-overexpressing breast cancers often show hyperactivation of the HER2/AKT/mTOR signaling pathway."5.39Autophagy stimulates apoptosis in HER2-overexpressing breast cancers treated by lapatinib. ( Chen, S; Feng, D; Han, T; Jiang, R; Liu, X; Ma, Y; Qiao, H; Wei, Y; Wu, L; Zhang, J; Zhang, S; Zhang, Y; Zhu, X, 2013)
"In MDA-MB-231 human breast cancer cells, overexpression of the small heat shock protein 27 (hsp27) results in a downregulation of c-Yes levels, concomitant with increased in vitro invasiveness and in vivo metastatic behavior."5.33The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells. ( Brewer, G; Cui, Y; Fuqua, SA; Sommer, S, 2005)
"Since breast cancers have been reported to carry MSI, although its frequencies were quite variable, we examined whether microsatellite mutation of the polyadenine tract occurs in the human breast cancer MDA-MB-231 cell line."5.31Deletion of one adenine base within the polyadenine tract of transforming growth factor-beta receptor type II in human MDA-MB-231 breast cancer cell line. ( Jang, JS; Park, B; Park, K, 2000)
"A total of 365 women with measurable metastatic breast cancer, previously untreated with chemotherapy for their metastatic disease, were randomized to receive either immediate chemotherapy with cyclophosphamide, doxorubicin, and fluorouracil (CAF) or up to four cycles of one of five sequential cohorts of single-agent drugs: trimetrexate, melphalan, amonafide, carboplatin, or elsamitrucin, followed by CAF."5.09Safety and efficacy of using a single agent or a phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: report of a randomized study--Cancer and Leukemia Group B 8642. ( Berry, DA; Cirrincione, C; Costanza, ME; Frei, E; Henderson, IC; McIntyre, OR; Norton, L; Schilsky, RL; Weiss, RB; Winer, E; Wood, WC, 1999)
"Twenty-eight patients with advanced breast cancer refractory to prior hormone and/or first-line chemotherapy (with or without anthracycline drugs) were treated with the investigational agent amonafide at a dose of 800 mg/m2 intravenously over 3 hours repeated every 4 weeks."5.07Phase II study of amonafide in advanced breast cancer. ( Depisch, D; Dittrich, C; Gisslinger, H; Haider, K; Kornek, G; Linkesch, W; Scheithauer, W, 1991)
"In a phase II study, 32 patients with advanced breast cancer previously unexposed to palliative cytotoxic chemotherapy were treated with amonafide, 800-900 mg intravenously over 3 h repeated every 4 weeks."5.07Amonafide as first-line chemotherapy for metastatic breast cancer. ( Depisch, D; Dittrich, C; Fazeny, B; Haider, K; Kornek, G; Raderer, M; Scheithauer, W, 1994)
" In this study, we reported that cyclovirobuxine D (CVB-D), an alkaloid component in a traditional Chinese herb, could induce autophagy in the MCF-7 human breast cancer cell line."3.80Cyclovirobuxine D induces autophagy-associated cell death via the Akt/mTOR pathway in MCF-7 human breast cancer cells. ( Gao, S; Gao, Y; Liu, P; Lu, J; Sun, D; Ye, J, 2014)
" In this study, we investigated the anticancer effects of sirtinol, a SIRT inhibitor, on MCF-7 human breast cancer cells."3.78Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells. ( Ahn, MY; Choi, WS; Jung, JH; Kim, HS; Kim, TH; Lee, BM; Lee, J; Wang, J; Yoon, KS; Yoon, S, 2012)
"Novel ruthenium-letrozole complexes have been prepared, and cell viability of two human cancer cell types (breast and glioblastoma) was determined."3.78New ruthenium(II)-letrozole complexes as anticancer therapeutics. ( Castonguay, A; Doucet, C; Juhas, M; Maysinger, D, 2012)
"In the National Surgical Adjuvant Breast and Bowel Project's Breast Cancer Prevention Project (BCPT), tamoxifen use was associated with an increased relative risk for venous thromboembolic events, including deep vein thrombosis and pulmonary emboli, compared with placebo."3.73Effect of Factor V Leiden and prothrombin G20210-->A mutations on thromboembolic risk in the national surgical adjuvant breast and bowel project breast cancer prevention trial. ( Abramson, N; Berliner, N; Costantino, JP; Garber, JE; Wickerham, DL; Wolmark, N, 2006)
"In this study we have examined the cytotoxic effects of different concentrations of adenosine (Ado) and deoxyadenosine (dAdo) on human breast cancer cell lines."3.73Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway. ( Ghavami, S; Hashemi, M; Karami-Tehrani, F; Los, M; Maddika, S, 2005)
" In this way, we obtained images showing the characteristic distribution of 14C-thymidine and D-arginine in human fibroblasts, and of 15N-adenine in organotypic cultures of human breast cancer cells."3.68Mapping the cellular distribution of labelled molecules by SIMS microscopy. ( Beaupain, R; Coulomb, B; Galle, P; Hindie, E, 1992)
"To determine if variability in toxicity of amonafide during phase II trials could be correlated with pharmacokinetic variability."2.68Population pharmacodynamic study of amonafide: a Cancer and Leukemia Group B study. ( Allen, SL; Costanza, M; Henderson, IC; Ratain, MJ; Rosner, G; Schilsky, RL; Van Echo, DA, 1995)
"Amonafide was chosen for inclusion in the Cancer and Leukemia Group B (CALGB) master metastatic breast cancer protocol."2.68Amonafide: An active agent in the treatment of previously untreated advanced breast cancer--a cancer and leukemia group B study (CALGB 8642). ( Berkowitz, I; Berry, D; Costanza, ME; Duggan, D; Henderson, IC; Kalra, J; Lyss, AP; Ratain, MJ; Shapiro, C; Wu, K, 1995)
"The management of metastatic breast cancer continues to provide enormous challenges."2.39Metastatic breast cancer. ( Kennedy, MJ, 1996)
"Using an orthotopic mouse breast cancer model, we show that ibrutinib inhibits the progression and metastasis of breast cancer."1.56Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells. ( Ahirwar, DK; Ganju, RK; Halsey, G; Hamza, O; Holcomb, EA; Jha, BK; Maryala, RJ; Oghumu, S; Saljoughian, N; Satoskar, AR; Singh, B; Varikuti, S; Verma, C; Viana, AG; Volpedo, G, 2020)
"Cancer recurrence after initial diagnosis and treatment is a major cause of breast cancer (BC) mortality, which results from the metastatic outbreak of dormant tumour cells."1.48Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. ( Green, JE; Hunter, KW; Nini, R; Vera-Ramirez, L; Vodnala, SK, 2018)
"Ibrutinib treatment impacts HER2(+) breast cancer cell viability at lower concentrations than the established breast cancer therapeutic lapatinib."1.43Bruton's Tyrosine Kinase Inhibitors Prevent Therapeutic Escape in Breast Cancer Cells. ( Conklin, DS; Khan, F; Kokabee, L; Sevinsky, CJ; Sun, Y; Wang, X; Wong, J, 2016)
"However, its effect on breast cancer cells remains unknown."1.43Ramalin-Mediated Apoptosis Is Enhanced by Autophagy Inhibition in Human Breast Cancer Cells. ( Lee, CG; Lee, E; Lee, HK; Pyo, S; Yim, JH, 2016)
"Breast cancer is one of the most common cancers affecting women worldwide."1.42Participation of autophagy in the cytotoxicity against breast cancer cells by cisplatin. ( Chen, K; Duan, WM; Gong, FR; Gui, Q; Li, DM; Li, W; Lian, L; Liu, L; Shen, M; Tao, M; Wang, WJ; Wu, MY; Xu, MD; Zhu, J, 2015)
"MDA‑MB‑231 human breast cancer cells were cultured in Dulbecco's modified Eagle's medium (DMEM) with high glucose, then divided into six groups."1.40Effect of autophagy inhibition on cell viability and cell cycle progression in MDA‑MB‑231 human breast cancer cells. ( Li, C; Liu, Q; Shi, X; Wang, D; Wang, L; Zhou, X, 2014)
"We found that MCF-7 and MDA-MB‑231 breast cancer cells were insensitive to TM at a relatively low concentration."1.40Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells. ( Chen, C; Cheng, X; Fang, L; Jiang, CC; Jiang, ZW; Liu, H; Zhang, XD, 2014)
"HER2-overexpressing breast cancers often show hyperactivation of the HER2/AKT/mTOR signaling pathway."1.39Autophagy stimulates apoptosis in HER2-overexpressing breast cancers treated by lapatinib. ( Chen, S; Feng, D; Han, T; Jiang, R; Liu, X; Ma, Y; Qiao, H; Wei, Y; Wu, L; Zhang, J; Zhang, S; Zhang, Y; Zhu, X, 2013)
"These findings were observed in breast cancer cell lines with an invasive phenotype and were further confirmed in ZFP36-knockout mouse fibroblasts."1.39miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer. ( Al-Ahmadi, W; Al-Ghamdi, M; Al-Souhibani, N; Khabar, KS, 2013)
"We report that in breast and prostate cancer cells that contain leukocyte levels of p110δ, p110δ activity dampens the activity of the PTEN tumor suppressor."1.38High levels of p110δ PI3K expression in solid tumor cells suppress PTEN activity, generating cellular sensitivity to p110δ inhibitors through PTEN activation. ( Andreou, M; Makrigiannakis, A; Papakonstanti, EA; Stratigi, K; Tzenaki, N; Vanhaesebroeck, B; Vergetaki, A, 2012)
"In human breast cancer tissue, the compounds demonstrated increased binding as compared to the fluorophore."1.37Fluorescent cyclin-dependent kinase inhibitors block the proliferation of human breast cancer cells. ( Brown, ML; Dakshanamurthy, S; Deb, TB; Grindrod, SC; Paige, M; Yang, Y; Yenugonda, VM, 2011)
"Risks of breast cancer associated with low-penetrance susceptibility polymorphisms do not vary significantly with these ten established environmental risk factors."1.36Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study. ( Baker, K; Bell, J; Beral, V; Bull, D; Green, J; Lathrop, M; Peto, R; Reeves, GK; Tipper, SJ; Travis, RC; Zelenika, D, 2010)
"In MDA-MB-231 human breast cancer cells, overexpression of the small heat shock protein 27 (hsp27) results in a downregulation of c-Yes levels, concomitant with increased in vitro invasiveness and in vivo metastatic behavior."1.33The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells. ( Brewer, G; Cui, Y; Fuqua, SA; Sommer, S, 2005)
"We evaluated XRCC1 gene expression in breast cancer cell lines and carcinogen-induced apoptosis in benign breast epithelial cells in relation to XRCC1 genotypes."1.33An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer. ( Bu, D; Euhus, DM; Kildebeck, E; Lewis, CM; Tomlinson, G; Zhang, C, 2006)
"In contrast, breast cancer patients with the variant allele at codon 677 (C/T or T/T) had improved survival, albeit not statistically significant, when compared to individuals with the common C/C genotype (HR = 0."1.33Association of MTHFR gene polymorphisms with breast cancer survival. ( Ambs, S; Boersma, BJ; Chanock, SJ; Goodman, JE; Howe, TM; Martin, DN; Mechanic, LE, 2006)
"The cases were 200 breast cancer patients who visited Aichi Cancer Center Hospital."1.32Association of p53 codon Arg72Pro and p73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of Japanese breast cancer. ( Hamajima, N; Hirose, K; Huang, XE; Iwata, H; Katsuda, N; Matsuo, K; Miura, S; Mizutani, M; Tajima, K; Tokudome, S; Xiang, J, 2003)
"Since breast cancers have been reported to carry MSI, although its frequencies were quite variable, we examined whether microsatellite mutation of the polyadenine tract occurs in the human breast cancer MDA-MB-231 cell line."1.31Deletion of one adenine base within the polyadenine tract of transforming growth factor-beta receptor type II in human MDA-MB-231 breast cancer cell line. ( Jang, JS; Park, B; Park, K, 2000)
"All patients had a family history of tumors previously associated with A-T heterozygosity or homozygosity."1.29ATM mutations in cancer families. ( Croce, CM; Hammarström, L; Lindblom, A; Luo, L; Negrini, M; Vorechovský, I; Webster, AD, 1996)

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-19903 (4.00)18.7374
1990's12 (16.00)18.2507
2000's18 (24.00)29.6817
2010's35 (46.67)24.3611
2020's7 (9.33)2.80

Authors

AuthorsStudies
Szklener, K1
Michalski, A1
Żak, K1
Piwoński, M1
Mańdziuk, S1
Varikuti, S1
Singh, B2
Volpedo, G1
Ahirwar, DK1
Jha, BK1
Saljoughian, N1
Viana, AG1
Verma, C1
Hamza, O1
Halsey, G1
Holcomb, EA1
Maryala, RJ1
Oghumu, S1
Ganju, RK1
Satoskar, AR1
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
Yan, Z1
Zhou, L1
Zhao, Y3
Wang, J7
Huang, L2
Hu, K1
Liu, H6
Wang, H3
Guo, Z1
Song, Y1
Huang, H4
Yang, R1
Owen, TW1
Al-Kaysi, RO1
Bardeen, CJ1
Cheng, Q1
Wu, S1
Cheng, T1
Zhou, X2
Wang, B4
Zhang, Q4
Wu, X2
Yao, Y3
Ochiai, T1
Ishiguro, H2
Nakano, R2
Kubota, Y2
Hara, M1
Sunada, K1
Hashimoto, K1
Kajioka, J1
Fujishima, A1
Jiao, J3
Gai, QY3
Wang, W2
Zang, YP2
Niu, LL2
Fu, YJ3
Wang, X6
Yao, LP1
Qin, QP1
Wang, ZY1
Liu, J4
Aleksic Sabo, V1
Knezevic, P1
Borges-Argáez, R1
Chan-Balan, R1
Cetina-Montejo, L1
Ayora-Talavera, G1
Sansores-Peraza, P1
Gómez-Carballo, J1
Cáceres-Farfán, M1
Jang, J1
Akin, D1
Bashir, R1
Yu, Z1
Zhu, J3
Jiang, H1
He, C2
Xiao, Z1
Xu, J2
Sun, Q1
Han, D1
Lei, H1
Zhao, K2
Zhu, L1
Li, X4
Fu, H2
Wilson, BK1
Step, DL1
Maxwell, CL1
Gifford, CA1
Richards, CJ1
Krehbiel, CR1
Warner, JM1
Doerr, AJ1
Erickson, GE1
Guretzky, JA1
Rasby, RJ1
Watson, AK1
Klopfenstein, TJ1
Sun, Y5
Liu, Z4
Pham, TD1
Lee, BK1
Yang, FC1
Wu, KH1
Lin, WP1
Hu, MK1
Lin, L3
Shao, J1
Sun, M1
Xu, G1
Zhang, X6
Xu, N1
Wang, R1
Liu, S1
He, H1
Dong, X2
Yang, M2
Yang, Q2
Duan, S1
Yu, Y2
Han, J2
Zhang, C4
Chen, L2
Yang, X1
Li, W5
Wang, T2
Campbell, DA1
Gao, K1
Zager, RA1
Johnson, ACM1
Guillem, A1
Keyser, J1
Steubl, D1
Schneider, MP1
Meiselbach, H1
Nadal, J1
Schmid, MC1
Saritas, T1
Krane, V1
Sommerer, C1
Baid-Agrawal, S1
Voelkl, J1
Kotsis, F1
Köttgen, A1
Eckardt, KU1
Scherberich, JE1
Li, H5
Yao, L2
Sun, L3
Zhu, Z1
Naren, N1
Zhang, XX2
Gentile, GL1
Rupert, AS1
Carrasco, LI1
Garcia, EM1
Kumar, NG1
Walsh, SW1
Jefferson, KK1
Guest, RL1
Samé Guerra, D1
Wissler, M1
Grimm, J1
Silhavy, TJ1
Lee, JH2
Yoo, JS1
Kim, Y2
Kim, JS3
Lee, EJ1
Roe, JH1
Delorme, M1
Bouchard, PA1
Simon, M1
Simard, S1
Lellouche, F1
D'Urzo, KA1
Mok, F1
D'Urzo, AD1
Koneru, B1
Lopez, G1
Farooqi, A1
Conkrite, KL1
Nguyen, TH1
Macha, SJ1
Modi, A1
Rokita, JL1
Urias, E1
Hindle, A1
Davidson, H1
Mccoy, K1
Nance, J1
Yazdani, V1
Irwin, MS1
Yang, S1
Wheeler, DA1
Maris, JM1
Diskin, SJ1
Reynolds, CP1
Abhilash, L1
Kalliyil, A1
Sheeba, V1
Hartley, AM2
Meunier, B2
Pinotsis, N1
Maréchal, A2
Xu, JY1
Genko, N1
Haraux, F1
Rich, PR1
Kamalanathan, M1
Doyle, SM1
Xu, C1
Achberger, AM1
Wade, TL1
Schwehr, K1
Santschi, PH1
Sylvan, JB1
Quigg, A1
Leong, W1
Xu, W2
Gao, S2
Zhai, X1
Wang, C2
Gilson, E1
Ye, J2
Lu, Y1
Yan, R1
Zhang, Y7
Hu, Z1
You, Q1
Cai, Q1
Yang, D1
Gu, S1
Dai, H1
Zhao, X1
Gui, C1
Gui, J1
Wu, PK1
Hong, SK1
Starenki, D1
Oshima, K1
Shao, H1
Gestwicki, JE1
Tsai, S1
Park, JI1
Wang, Y7
Zhao, R1
Gu, Z1
Dong, C2
Guo, G1
Li, L4
Barrett, HE1
Meester, EJ1
van Gaalen, K1
van der Heiden, K1
Krenning, BJ1
Beekman, FJ1
de Blois, E1
de Swart, J1
Verhagen, HJ1
Maina, T1
Nock, BA1
Norenberg, JP1
de Jong, M1
Gijsen, FJH1
Bernsen, MR1
Martínez-Milla, J1
Galán-Arriola, C1
Carnero, M1
Cobiella, J1
Pérez-Camargo, D1
Bautista-Hernández, V1
Rigol, M1
Solanes, N1
Villena-Gutierrez, R1
Lobo, M1
Mateo, J1
Vilchez-Tschischke, JP1
Salinas, B1
Cussó, L1
López, GJ1
Fuster, V1
Desco, M1
Sanchez-González, J1
Ibanez, B1
van den Berg, P1
Schweitzer, DH1
van Haard, PMM1
Geusens, PP1
van den Bergh, JP1
Zhu, X2
Huang, X3
Xu, H2
Yang, G2
Lin, Z1
Salem, HF1
Nafady, MM1
Kharshoum, RM1
Abd El-Ghafar, OA1
Farouk, HO1
Domiciano, D1
Nery, FC1
de Carvalho, PA1
Prudente, DO1
de Souza, LB1
Chalfun-Júnior, A1
Paiva, R1
Marchiori, PER1
Lu, M3
An, Z1
Jiang, J2
Li, J8
Du, S1
Zhou, H1
Cui, J1
Wu, W1
Liu, Y8
Song, J1
Lian, Q1
Uddin Ahmad, Z1
Gang, DD1
Konggidinata, MI1
Gallo, AA1
Zappi, ME1
Yang, TWW1
Johari, Y1
Burton, PR1
Earnest, A1
Shaw, K1
Hare, JL1
Brown, WA1
Kim, GA1
Han, S1
Choi, GH1
Choi, J1
Lim, YS1
Gallo, A1
Cancelli, C1
Ceron, E1
Covino, M1
Capoluongo, E1
Pocino, K1
Ianiro, G1
Cammarota, G1
Gasbarrini, A1
Montalto, M1
Somasundar, Y1
Lu, IC1
Mills, MR1
Qian, LY1
Olivares, X1
Ryabov, AD1
Collins, TJ1
Zhao, L1
Doddipatla, S1
Thomas, AM1
Nikolayev, AA1
Galimova, GR1
Azyazov, VN1
Mebel, AM1
Kaiser, RI1
Guo, S1
Yang, P1
Yu, X2
Wu, Y2
Zhang, H1
Yu, B2
Han, B1
George, MW1
Moor, MB1
Bonny, O1
Langenberg, E1
Paik, H1
Smith, EH1
Nair, HP1
Hanke, I1
Ganschow, S1
Catalan, G1
Domingo, N1
Schlom, DG1
Assefa, MK1
Wu, G2
Hayton, TW1
Becker, B1
Enikeev, D1
Netsch, C1
Gross, AJ1
Laukhtina, E1
Glybochko, P1
Rapoport, L1
Herrmann, TRW1
Taratkin, M1
Dai, W1
Shi, J2
Carreno, J1
Kloner, RA1
Pickersgill, NA1
Vetter, JM1
Kim, EH1
Cope, SJ1
Du, K1
Venkatesh, R1
Giardina, JD1
Saad, NES1
Bhayani, SB1
Figenshau, RS1
Eriksson, J1
Landfeldt, E1
Ireland, S1
Jackson, C1
Wyatt, E1
Gaudig, M1
Stancill, JS1
Happ, JT1
Broniowska, KA1
Hogg, N1
Corbett, JA1
Tang, LF1
Bi, YL1
Fan, Y2
Sun, YB1
Wang, AL1
Xiao, BH1
Wang, LF1
Qiu, SW1
Guo, SW1
Wáng, YXJ1
Sun, J2
Chu, S1
Pan, Q1
Li, D2
Zheng, S2
Ma, L1
Wang, L4
Hu, T1
Wang, F1
Han, Z1
Yin, Z1
Ge, X1
Xie, K1
Lei, P1
Dias-Santagata, D1
Lennerz, JK1
Sadow, PM1
Frazier, RP1
Govinda Raju, S1
Henry, D1
Chung, T1
Kherani, J1
Rothenberg, SM1
Wirth, LJ1
Marti, CN1
Choi, NG1
Bae, SJ1
Ni, L1
Luo, X1
Dai, T1
Yang, Y4
Lee, R1
Fleischer, AS1
Wemhoff, AP1
Ford, CR1
Kleppinger, EL1
Helms, K1
Bush, AA1
Luna-Abanto, J1
García Ruiz, L1
Laura Martinez, J1
Álvarez Larraondo, M1
Villoslada Terrones, V1
Dukic, L1
Maric, N1
Simundic, AM1
Chogtu, B1
Ommurugan, B1
Thomson, SR1
Kalthur, SG1
Benidir, M1
El Massoudi, S1
El Ghadraoui, L1
Lazraq, A1
Benjelloun, M1
Errachidi, F1
Cassar, M1
Law, AD1
Chow, ES1
Giebultowicz, JM1
Kretzschmar, D1
Salonurmi, T1
Nabil, H1
Ronkainen, J1
Hyötyläinen, T1
Hautajärvi, H1
Savolainen, MJ1
Tolonen, A1
Orešič, M1
Känsäkoski, P1
Rysä, J1
Hakkola, J1
Hukkanen, J1
Zhu, N1
Li, Y4
Du, Q1
Hao, P1
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Khabar, KS1
McClellan, MB1
WHEELER, GP1
ALEXANDER, JA1
DODSON, AS1
BRIGGS, SD1
COSTAKEL, O1
Huang, XE1
Hamajima, N1
Katsuda, N1
Matsuo, K1
Hirose, K1
Mizutani, M1
Iwata, H1
Miura, S1
Xiang, J1
Tokudome, S1
Tajima, K1
Fan, XY1
Huo, H1
Huang, WD1
Che, X1
Wang, XF1
Høyer-Hansen, M1
Bastholm, L1
Mathiasen, IS1
Elling, F1
Jäättelä, M1
Hashemi, M1
Karami-Tehrani, F1
Ghavami, S1
Maddika, S1
Los, M1
Sommer, S1
Brewer, G1
Fuqua, SA1
Lavieu, G1
Scarlatti, F1
Sala, G1
Carpentier, S1
Levade, T1
Ghidoni, R1
Botti, J1
Codogno, P1
Bu, D1
Tomlinson, G1
Lewis, CM1
Kildebeck, E1
Euhus, DM1
Abramson, N1
Costantino, JP1
Garber, JE1
Berliner, N1
Wickerham, DL1
Wolmark, N1
Boersma, BJ2
Howe, TM2
Goodman, JE2
Yfantis, HG1
Lee, DH1
Chanock, SJ2
Ambs, S2
Martin, DN1
Mechanic, LE1
Imaoka, T1
Kusuhara, H1
Adachi, M1
Schuetz, JD1
Takeuchi, K1
Sugiyama, Y1
Alami, N1
Paterson, J1
Belanger, S1
Juste, S1
Grieshaber, CK1
Leyland-Jones, B1
Muranaka, K1
Sano, A1
Ichikawa, S1
Matsuda, A1
Iyer, VK1
Butler, WB1
Horwitz, JP1
Rozhin, J1
Brooks, SC1
Corombos, J1
Kessel, D1
Ratain, MJ2
Rosner, G1
Allen, SL1
Costanza, M1
Van Echo, DA1
Henderson, IC3
Schilsky, RL2
Kornek, G2
Raderer, M1
Depisch, D2
Haider, K2
Fazeny, B1
Dittrich, C2
Scheithauer, W2
Vorechovský, I1
Lindblom, A1
Negrini, M1
Webster, AD1
Croce, CM1
Hammarström, L1
Kennedy, MJ1
Cerda, SR1
Turk, PW1
Thor, AD1
Weitzman, SA1
van Kuilenburg, AB1
Vreken, P1
Beex, LV1
De Abreu, RA1
van Gennip, AH1
Costanza, ME2
Berry, D1
Wu, K1
Shapiro, C1
Duggan, D1
Kalra, J1
Berkowitz, I1
Lyss, AP1
Weiss, RB1
Norton, L1
Berry, DA1
Cirrincione, C1
Winer, E1
Wood, WC1
Frei, E1
McIntyre, OR1
Barry, CP1
Lind, SE1
Park, B1
Jang, JS1
Park, K1
Ameyaw, MM1
Thornton, N1
McLeod, HL1
de Kreuk, AM1
Jonkhoff, AR1
Zevenbergen, A1
Hendriks, EC1
Schuurhuis, GJ1
Ossenkoppele, GJ1
Dräger, AM1
van Oostveen, JW1
Huijgens, PC1
Hindie, E1
Coulomb, B1
Beaupain, R1
Galle, P1
Malins, DC1
Haimanot, R1
Linkesch, W1
Gisslinger, H1
Barbieri, R1
Ruisi, G1
Atassi, G1

Reviews

4 reviews available for adenine and Breast Cancer

ArticleYear
Ibrutinib in the Treatment of Solid Tumors: Current State of Knowledge and Future Directions.
    Cells, 2022, 04-14, Volume: 11, Issue:8

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Breast Neoplasms; Female; Humans; Piperidines

2022
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Ibrutinib in Gynecological Malignancies and Breast Cancer: A Systematic Review.
    International journal of molecular sciences, 2020, Jun-10, Volume: 21, Issue:11

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Breast Neoplasms; Clin

2020
Metastatic breast cancer.
    Current opinion in oncology, 1996, Volume: 8, Issue:6

    Topics: Adenine; Antibodies, Monoclonal; Antibodies, Neoplasm; Antimetabolites, Antineoplastic; Antineoplast

1996

Trials

6 trials available for adenine and Breast Cancer

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Population pharmacodynamic study of amonafide: a Cancer and Leukemia Group B study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:3

    Topics: Acetylation; Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Femal

1995
Amonafide as first-line chemotherapy for metastatic breast cancer.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:3

    Topics: Adenine; Adult; Aged; Agranulocytosis; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Imid

1994
Amonafide: An active agent in the treatment of previously untreated advanced breast cancer--a cancer and leukemia group B study (CALGB 8642).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:7

    Topics: Adenine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophospha

1995
Safety and efficacy of using a single agent or a phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: report of a randomized study--Cancer and Leukemia Group B 8642.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:5

    Topics: Adenine; Adult; Aged; Aminoglycosides; Analysis of Variance; Anti-Bacterial Agents; Antineoplastic C

1999
Phase II study of amonafide in advanced breast cancer.
    Breast cancer research and treatment, 1991, Volume: 20, Issue:1

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cardiomyopathies; Drug Evaluation; Fe

1991

Other Studies

66 other studies available for adenine and Breast Cancer

ArticleYear
Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells.
    British journal of cancer, 2020, Volume: 122, Issue:7

    Topics: Adenine; Animals; Breast Neoplasms; Dendritic Cells; Disease Progression; Female; Humans; Mice; Myel

2020
Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study.
    BMC cancer, 2021, Feb-25, Volume: 21, Issue:1

    Topics: Adenine; AMP-Activated Protein Kinases; Apoptosis; Autophagy; Autophagy-Related Protein-1 Homolog; B

2021
Bruton's agammaglobulinemia tyrosine kinase (Btk) regulates TPA‑induced breast cancer cell invasion via PLCγ2/PKCβ/NF‑κB/AP‑1‑dependent matrix metalloproteinase‑9 activation.
    Oncology reports, 2021, Volume: 45, Issue:5

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Breast Neoplasms; Cell Movement; Female; Gene Expressi

2021
PINK1/Parkin-mediated mitophagy inhibits warangalone-induced mitochondrial apoptosis in breast cancer cells.
    Aging, 2021, 04-30, Volume: 13, Issue:9

    Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Breast Neoplasms; Cel

2021
TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway.
    Scientific reports, 2017, 06-09, Volume: 7, Issue:1

    Topics: Adenine; AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Aut

2017
Delivery of Amonafide from Fructose-Coated Nanodiamonds by Oxime Ligation for the Treatment of Human Breast Cancer.
    Biomacromolecules, 2018, 02-12, Volume: 19, Issue:2

    Topics: Adenine; Breast Neoplasms; Coated Materials, Biocompatible; Drug Delivery Systems; Female; Fructose;

2018
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence.
    Nature communications, 2018, 05-22, Volume: 9, Issue:1

    Topics: Adenine; Animals; Autophagy; Autophagy-Related Protein 7; Beclin-1; Breast Neoplasms; Caspases; Cell

2018
Pharmacological inactivation of the PI3K p110δ prevents breast tumour progression by targeting cancer cells and macrophages.
    Cell death & disease, 2018, 06-07, Volume: 9, Issue:6

    Topics: Adenine; Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival;

2018
Ibrutinib as a potential therapeutic option for HER2 overexpressing breast cancer - the role of STAT3 and p21.
    Investigational new drugs, 2020, Volume: 38, Issue:4

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Ce

2020
Autophagy stimulates apoptosis in HER2-overexpressing breast cancers treated by lapatinib.
    Journal of cellular biochemistry, 2013, Volume: 114, Issue:12

    Topics: Adenine; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene

2013
Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adenine; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Aut

2013
A high-content, multiplexed screen in human breast cancer cells identifies profilin-1 inducers with anti-migratory activities.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adenine; Breast Neoplasms; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Female; Gene Knoc

2014
Cyclovirobuxine D induces autophagy-associated cell death via the Akt/mTOR pathway in MCF-7 human breast cancer cells.
    Journal of pharmacological sciences, 2014, Volume: 125, Issue:1

    Topics: Adenine; Autophagy; Autophagy-Related Protein 5; Breast Neoplasms; Cell Survival; Dose-Response Rela

2014
Autophagy inhibitor 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells.
    European journal of nutrition, 2015, Volume: 54, Issue:2

    Topics: Adenine; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumo

2015
Effect of autophagy inhibition on cell viability and cell cycle progression in MDA‑MB‑231 human breast cancer cells.
    Molecular medicine reports, 2014, Volume: 10, Issue:2

    Topics: Adenine; Apoptosis; Autophagy; Autophagy-Related Protein 7; Breast Neoplasms; Cell Cycle Checkpoints

2014
Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells.
    International journal of molecular medicine, 2014, Volume: 34, Issue:3

    Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Breast Neoplasms; Cell Line,

2014
Ibrutinib (ImbruvicaTM) potently inhibits ErbB receptor phosphorylation and cell viability of ErbB2-positive breast cancer cells.
    Investigational new drugs, 2014, Volume: 32, Issue:6

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Breast Neoplasms; Cell

2014
Raloxifene induces autophagy-dependent cell death in breast cancer cells via the activation of AMP-activated protein kinase.
    Molecules and cells, 2015, Volume: 38, Issue:2

    Topics: Adenine; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis Regulatory Proteins; Autoph

2015
Multiclass comparative virtual screening to identify novel Hsp90 inhibitors: a therapeutic breast cancer drug target.
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:1

    Topics: Adenine; Anisoles; Antineoplastic Agents; Benzamides; Binding Sites; Breast Neoplasms; Catechin; Dat

2015
Participation of autophagy in the cytotoxicity against breast cancer cells by cisplatin.
    Oncology reports, 2015, Volume: 34, Issue:1

    Topics: Adenine; Antineoplastic Agents; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Cyclophosp

2015
Inhibition of Autophagy Increases Proliferation Inhibition and Apoptosis Induced by the PI3K/mTOR Inhibitor NVP-BEZ235 in Breast Cancer Cells.
    Clinical laboratory, 2015, Volume: 61, Issue:8

    Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Autophagy-Related Pro

2015
Ramalin-Mediated Apoptosis Is Enhanced by Autophagy Inhibition in Human Breast Cancer Cells.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:3

    Topics: Adenine; Antineoplastic Agents; Antioxidants; Apoptosis; Apoptosis Inducing Factor; Autophagy; Autop

2016
Antitumor activity of a novel small molecule TLR7 agonist via immune response induction and tumor microenvironment modulation.
    Oncology reports, 2016, Volume: 35, Issue:2

    Topics: Adenine; Animals; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Disease Models, Animal

2016
Radiation induces autophagic cell death via the p53/DRAM signaling pathway in breast cancer cells.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1;

2016
Bruton's Tyrosine Kinase Inhibitors Prevent Therapeutic Escape in Breast Cancer Cells.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:9

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Apoptosis; Breast Neop

2016
Targeting cancer cells through antibiotics-induced mitochondrial dysfunction requires autophagy inhibition.
    Cancer letters, 2017, 01-01, Volume: 384

    Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protoco

2017
Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro.
    Acta pharmacologica Sinica, 2017, Volume: 38, Issue:2

    Topics: Adenine; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; Dose

2017
Inhibition of Inositol 1, 4, 5-Trisphosphate Receptor Induce Breast Cancer Cell Death Through Deregulated Autophagy and Cellular Bioenergetics.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:8

    Topics: Acetylcysteine; Adenine; Autophagy; Autophagy-Related Protein 5; Blotting, Western; Breast Neoplasms

2017
VMY-1-103, a dansylated analog of purvalanol B, induces caspase-3-dependent apoptosis in LNCaP prostate cancer cells.
    Cancer biology & therapy, 2010, Aug-15, Volume: 10, Issue:4

    Topics: Adenine; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor

2010
Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study.
    Lancet (London, England), 2010, Jun-19, Volume: 375, Issue:9732

    Topics: Adenine; Age Factors; Alcohol Drinking; Apoptosis Regulatory Proteins; Ataxia Telangiectasia Mutated

2010
Fluorescent cyclin-dependent kinase inhibitors block the proliferation of human breast cancer cells.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Adenine; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neop

2011
Autophagy contributes to resistance of tumor cells to ionizing radiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:3

    Topics: Adenine; Autophagy; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell

2011
New approach to analyze genetic and clinical data in bisphosphonate-induced osteonecrosis of the jaw.
    Oral diseases, 2012, Volume: 18, Issue:6

    Topics: Adenine; Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic

2012
High levels of p110δ PI3K expression in solid tumor cells suppress PTEN activity, generating cellular sensitivity to p110δ inhibitors through PTEN activation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:6

    Topics: Adenine; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Class Ia Phosphatidylinosi

2012
Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells.
    International journal of oncology, 2012, Volume: 41, Issue:3

    Topics: Acetylation; Adenine; Apoptosis; Autophagy; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associ

2012
New ruthenium(II)-letrozole complexes as anticancer therapeutics.
    Journal of medicinal chemistry, 2012, Oct-25, Volume: 55, Issue:20

    Topics: Adenine; Adenocarcinoma; Antineoplastic Agents; Aromatase Inhibitors; Autophagy; Breast Neoplasms; C

2012
Rapamycin induces apoptosis when autophagy is inhibited in T-47D mammary cells and both processes are regulated by Phlda1.
    Cell biochemistry and biophysics, 2013, Volume: 66, Issue:3

    Topics: Adenine; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Humans; Oligonucleotide Array Seq

2013
Effects of steroidal aromatase inhibitors on sensitive and resistant breast cancer cells: aromatase inhibition and autophagy.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 135

    Topics: Adenine; Androstanes; Aromatase Inhibitors; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Surv

2013
miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer.
    The Journal of pathology, 2013, Volume: 230, Issue:1

    Topics: Adenine; Animals; Breast Neoplasms; ELAV Proteins; Female; Fibroblasts; Gene Expression Regulation,

2013
From the Food and Drug Administration.
    JAMA, 2002, Nov-06, Volume: 288, Issue:17

    Topics: Adenine; Anastrozole; Antineoplastic Agents, Hormonal; Antiviral Agents; Breast Neoplasms; Chemother

2002
Searches for exploitable biochemical differences between normal and cancer cells. X. Catabolism of purines by regressing tumors.
    Cancer research, 1962, Volume: 22

    Topics: Adenine; Breast Neoplasms; Castration; Diethylstilbestrol; Guanine; Humans; Hypophysectomy; Plasmacy

1962
THE CHEMOTHERAPY OF CANCER WITH MASSIVE DOSES UNDER THE PROTECTION OF PERFUSION OF AUTOGENOUS HEMATOPOIETIC TISSUE.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Adenine; Bone Marrow Transplantation; Breast Neoplasms; DNA; Female; Folic Acid; Humans; Lung Neopla

1964
Association of p53 codon Arg72Pro and p73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of Japanese breast cancer.
    Breast cancer (Tokyo, Japan), 2003, Volume: 10, Issue:4

    Topics: Adenine; Adult; Aged; Arginine; Breast Neoplasms; Carcinoma, Ductal; Case-Control Studies; Codon; Cy

2003
[Fourier transform infrared spectra analysis of nucleic acid in human breast tissue].
    Guang pu xue yu guang pu fen xi = Guang pu, 2004, Volume: 24, Issue:1

    Topics: Adenine; Breast Neoplasms; Female; Guanine; Humans; Nucleic Acids; Spectroscopy, Fourier Transform I

2004
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.
    Cell death and differentiation, 2005, Volume: 12, Issue:10

    Topics: Adenine; Antineoplastic Agents; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Breast Neoplasms

2005
Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.
    Cell proliferation, 2005, Volume: 38, Issue:5

    Topics: Adenine; Adenosine; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; C

2005
The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 97, Issue:3

    Topics: 3' Untranslated Regions; Adenine; Antigens, Surface; Breast Neoplasms; Down-Regulation; ELAV Protein

2005
Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation.
    The Journal of biological chemistry, 2006, Mar-31, Volume: 281, Issue:13

    Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 7; Beclin-1;

2006
An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer.
    Breast cancer research and treatment, 2006, Volume: 99, Issue:3

    Topics: Adenine; Adult; Apoptosis; Base Sequence; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Case-Contro

2006
Effect of Factor V Leiden and prothrombin G20210-->A mutations on thromboembolic risk in the national surgical adjuvant breast and bowel project breast cancer prevention trial.
    Journal of the National Cancer Institute, 2006, Jul-05, Volume: 98, Issue:13

    Topics: Adenine; Adult; Aged; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Facto

2006
Association of breast cancer outcome with status of p53 and MDM2 SNP309.
    Journal of the National Cancer Institute, 2006, Jul-05, Volume: 98, Issue:13

    Topics: Adenine; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Female; Guanine; Ha

2006
Association of MTHFR gene polymorphisms with breast cancer survival.
    BMC cancer, 2006, Oct-27, Volume: 6

    Topics: Adenine; Black or African American; Breast Neoplasms; Cytosine; Female; Genotype; Humans; Methylenet

2006
Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir.
    Molecular pharmacology, 2007, Volume: 71, Issue:2

    Topics: Adenine; Adenosine Triphosphate; Animals; Antiviral Agents; Breast Neoplasms; Drug Resistance, Neopl

2007
Comparative analysis of xanafide cytotoxicity in breast cancer cell lines.
    British journal of cancer, 2007, Jul-02, Volume: 97, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cel

2007
Synthesis of Hsp90 inhibitor dimers as potential antitumor agents.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Adenine; Anisoles; Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Dimeriz

2008
Some adenine and adenosine methylene-bridged estrogens.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:2

    Topics: Adenine; Adenosine; Animals; Breast Neoplasms; Cell Line; Drug Evaluation, Preclinical; Estradiol Co

1983
ATM mutations in cancer families.
    Cancer research, 1996, Sep-15, Volume: 56, Issue:18

    Topics: Adenine; Alleles; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; C

1996
Altered expression of the DNA repair protein, N-methylpurine-DNA glycosylase (MPG) in breast cancer.
    FEBS letters, 1998, Jul-10, Volume: 431, Issue:1

    Topics: Adenine; Amino Acid Sequence; Breast; Breast Neoplasms; Cells, Cultured; DNA Glycosylases; DNA Repai

1998
Severe 5-fluorouracil toxicity caused by reduced dihydropyrimidine dehydrogenase activity due to heterozygosity for a G-->A point mutation.
    Journal of inherited metabolic disease, 1998, Volume: 21, Issue:3

    Topics: Adenine; Antimetabolites, Antineoplastic; Breast Neoplasms; Cells, Cultured; Dihydrouracil Dehydroge

1998
Adenosine-mediated killing of cultured epithelial cancer cells.
    Cancer research, 2000, Apr-01, Volume: 60, Issue:7

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; C

2000
Deletion of one adenine base within the polyadenine tract of transforming growth factor-beta receptor type II in human MDA-MB-231 breast cancer cell line.
    International journal of oncology, 2000, Volume: 17, Issue:3

    Topics: Adenine; Animals; Breast Neoplasms; Cell Division; Cell Line; Codon; DNA Mutational Analysis; DNA, N

2000
Re: population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.
    Journal of the National Cancer Institute, 2000, Dec-06, Volume: 92, Issue:23

    Topics: Adenine; Africa; Alleles; Black or African American; Black People; Breast Neoplasms; Case-Control St

2000
Storage of unprocessed G-CSF-mobilized whole blood in a modified Leibovitz's L15 medium preserves clonogenic capacity for at least 7 days.
    Bone marrow transplantation, 2001, Volume: 28, Issue:2

    Topics: Adenine; Antigens, CD; Antigens, CD34; Blood Preservation; Breast Neoplasms; Cell Culture Techniques

2001
Mapping the cellular distribution of labelled molecules by SIMS microscopy.
    Biology of the cell, 1992, Volume: 74, Issue:1

    Topics: Adenine; Adult; Arginine; Breast Neoplasms; Carbon Radioisotopes; Cells, Cultured; Deuterium; Female

1992
Major alterations in the nucleotide structure of DNA in cancer of the female breast.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Adenine; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Transformation, Neoplastic;

1991
The antitumor activity and the structure of bis(adeninato-N9) diphenyltin(IV).
    Journal of inorganic biochemistry, 1991, Volume: 41, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Colonic Neoplasms; Female; Hum

1991