Page last updated: 2024-10-16

adenine and Brain Inflammation

adenine has been researched along with Brain Inflammation in 9 studies

Research Excerpts

ExcerptRelevanceReference
"This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats."8.02INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021)
"The susceptibility of herpes simplex type 1 and type 2 viruses to 9-beta-d-arabinofuranosyladenine (ara-A) was tested in intracerebrally infected mice."7.65Treatment of herpes simplex virus types 1 and 2 encephalitis in mice with 9-beta-D-arabinofuranosyladenine. ( McLean, IW; Miller, FA; Sloan, BJ, 1973)
"This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats."4.02INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021)
"Three hundred four animals were used for the systematic evaluation of the in vivo efficacy of 5-iodo-2'-deoxyuridine (IUDR), cytosire arabinoside, 9-beta-arabinofuranosyladenine, and isoprinosine in the therapy of herpes simplex encephalitis in an adult rat model."3.65Evaluation of four antiviral agents in the treatment of herpes simplex encephalitis in a rat model. ( Marks, MI, 1975)
"The susceptibility of herpes simplex type 1 and type 2 viruses to 9-beta-d-arabinofuranosyladenine (ara-A) was tested in intracerebrally infected mice."3.65Treatment of herpes simplex virus types 1 and 2 encephalitis in mice with 9-beta-D-arabinofuranosyladenine. ( McLean, IW; Miller, FA; Sloan, BJ, 1973)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Kim, JY1
Yi, MH1
Kim, M1
Yeom, JS1
Yoo, HD1
Kim, SM1
Yong, TS1
Jin, P1
Deng, S1
Tian, M1
Lenahan, C1
Wei, P1
Wang, Y1
Tan, J1
Wen, H1
Zhao, F1
Gao, Y1
Gong, Y1
Zhao, Q1
Che, X1
Zhang, H1
Fan, P1
Tan, G1
Liu, L1
Jiang, D1
Zhao, J1
Xiang, X1
Liang, Y1
Sun, X1
He, Z1
Meunier, J1
Borjini, N1
Gillis, C1
Villard, V1
Maurice, T1
LOW, IE1
EATON, MD1
Marks, MI1
Miyai, K1
Allen, LB1
Huffman, JH1
Sidwell, RW1
Tolman, RL1
Lerner, AM1
Lauter, CB1
Nolan, DC1
Sloan, BJ1
Miller, FA1
McLean, IW1

Other Studies

9 other studies available for adenine and Brain Inflammation

ArticleYear
Diagnosis of
    Annals of laboratory medicine, 2022, Mar-01, Volume: 42, Issue:2

    Topics: Adenine; Balamuthia mandrillaris; Cloning, Molecular; Encephalitis; Eukaryota; Humans; Male; Middle

2022
INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis.
    Experimental neurology, 2021, Volume: 335

    Topics: Adenine; Animals; Anxiety; Cholic Acids; Cognitive Dysfunction; Cyclic AMP; Cyclic AMP Response Elem

2021
Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage.
    Journal of neuroinflammation, 2017, 05-11, Volume: 14, Issue:1

    Topics: Adenine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blood-Brain Barrier; Brain Ede

2017
Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 44, Issue:2

    Topics: Adenine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Age

2015
Action of adenine and related compounds on replication of encephalomyocarditis virus in tissue culture.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 109

    Topics: Adenine; DNA Replication; Encephalitis; Encephalomyocarditis virus; Myocarditis; Tissue Culture Tech

1962
Evaluation of four antiviral agents in the treatment of herpes simplex encephalitis in a rat model.
    The Journal of infectious diseases, 1975, Volume: 131, Issue:1

    Topics: Acetanilides; Adenine; Animals; Antiviral Agents; Arabinose; Brain; Cell Line; Culture Techniques; C

1975
Synthesis and anti-deoxyribonucleic acid virus activity of certain 9-beta-D-arabinofuranosyl-2-substituted adenine derivatives.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:2

    Topics: Adenine; Adenoviridae; Animals; Arabinose; Carcinoma; Cell Line; Cricetinae; Cytopathogenic Effect,

1974
Herpes simplex virus encephalitis: therapy trials.
    Annals of internal medicine, 1973, Volume: 79, Issue:2

    Topics: Adenine; Arabinose; Encephalitis; Herpes Simplex; Humans; Idoxuridine; Nucleosides

1973
Treatment of herpes simplex virus types 1 and 2 encephalitis in mice with 9-beta-D-arabinofuranosyladenine.
    Antimicrobial agents and chemotherapy, 1973, Volume: 3, Issue:1

    Topics: Adenine; Animals; Antiviral Agents; Arabinose; Encephalitis; Herpes Simplex; Male; Mice; Mice, Inbre

1973