adenine has been researched along with Blood Poisoning in 16 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats." | 8.02 | INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021) |
| " The aim of this study was to verify the hypothesis that adenosine deaminase-1 and cyclic guanosine monophosphate-stimulated phosphodiesterase inhibition by erythro-9-[2-hydroxyl-3-nonyl]-adenine could be beneficial in experimental endotoxicosis/sepsis." | 7.74 | The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. ( Bardenheuer, H; Conzelmann, LO; Funke, B; Hofer, S; Kayhan, N; Schmidt, H; Steppan, J; Vahl, CF; Weigand, MA; Winkler, H, 2008) |
| "Sinomenine (SIN) is a natural alkaloid extracted from Chinese medicinal plant Sinomenium acutum, and its hydrochloride salt (Sinomenine hydrochloride, SIN-HCl) is widely used to treat rheumatoid arthritis (RA)." | 5.42 | Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy. ( Chen, G; Gao, M; Jiang, Y; Lang, Y; Liu, M; Tong, Z; Wang, K; Wang, W; Xiao, X; Yao, Y; Zhang, H, 2015) |
| "This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats." | 4.02 | INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021) |
| " The aim of this study was to verify the hypothesis that adenosine deaminase-1 and cyclic guanosine monophosphate-stimulated phosphodiesterase inhibition by erythro-9-[2-hydroxyl-3-nonyl]-adenine could be beneficial in experimental endotoxicosis/sepsis." | 3.74 | The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. ( Bardenheuer, H; Conzelmann, LO; Funke, B; Hofer, S; Kayhan, N; Schmidt, H; Steppan, J; Vahl, CF; Weigand, MA; Winkler, H, 2008) |
| "Sepsis is a life-threatening condition which affects multiple organs including the kidney." | 1.62 | Bruton's tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice. ( Ahmad, SF; Al-Harbi, NO; Alanazi, WA; Alqahtani, F; Alsanea, S; Attia, SM; Ibrahim, KE; Mahmood, HM; Nadeem, A, 2021) |
| "Sepsis is one of the most prevalent diseases in the world." | 1.51 | Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice. ( Al Zoubi, S; Chiazza, F; Coldewey, SM; Collino, M; Collotta, D; Martin, L; O'Riordan, CE; Purvis, GSD; Stiehler, L; Thiemermann, C; Wissuwa, B, 2019) |
| "Sinomenine (SIN) is a natural alkaloid extracted from Chinese medicinal plant Sinomenium acutum, and its hydrochloride salt (Sinomenine hydrochloride, SIN-HCl) is widely used to treat rheumatoid arthritis (RA)." | 1.42 | Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy. ( Chen, G; Gao, M; Jiang, Y; Lang, Y; Liu, M; Tong, Z; Wang, K; Wang, W; Xiao, X; Yao, Y; Zhang, H, 2015) |
| "Sepsis was induced by cecal ligation and puncture (CLP)." | 1.40 | Complete activation of autophagic process attenuates liver injury and improves survival in septic mice. ( Chang, YF; Hsieh, YC; Kuo, PL; Lee, PH; Lin, CW; Lo, S; Perng, DS; Wu, DB; Yu, ML; Yuan, SS, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 6 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| O'Riordan, CE | 2 |
| Purvis, GSD | 2 |
| Collotta, D | 2 |
| Chiazza, F | 1 |
| Wissuwa, B | 2 |
| Al Zoubi, S | 1 |
| Stiehler, L | 1 |
| Martin, L | 1 |
| Coldewey, SM | 2 |
| Collino, M | 2 |
| Thiemermann, C | 2 |
| Jin, P | 1 |
| Deng, S | 1 |
| Tian, M | 1 |
| Lenahan, C | 1 |
| Wei, P | 1 |
| Wang, Y | 1 |
| Tan, J | 1 |
| Wen, H | 1 |
| Zhao, F | 1 |
| Gao, Y | 1 |
| Gong, Y | 1 |
| Wang, X | 2 |
| Zhu, Y | 1 |
| Zhou, Q | 1 |
| Yan, Y | 1 |
| Qu, J | 1 |
| Ye, H | 1 |
| Krieg, N | 1 |
| Sheikh, MH | 1 |
| Ferreira Alves, G | 1 |
| Mohammad, S | 1 |
| Callender, LA | 1 |
| Greaves, DR | 1 |
| Nadeem, A | 1 |
| Ahmad, SF | 1 |
| Al-Harbi, NO | 1 |
| Ibrahim, KE | 1 |
| Alqahtani, F | 1 |
| Alanazi, WA | 1 |
| Mahmood, HM | 1 |
| Alsanea, S | 1 |
| Attia, SM | 1 |
| Saling, C | 1 |
| Feller, F | 1 |
| Vikram, HR | 1 |
| Tang, R | 1 |
| Jia, L | 1 |
| Li, Y | 1 |
| Zheng, J | 1 |
| Qi, P | 1 |
| Li, Q | 1 |
| Li, L | 1 |
| Fei, X | 1 |
| Zhang, Y | 1 |
| Qi, C | 1 |
| Hua, S | 1 |
| Gong, F | 1 |
| Fang, M | 1 |
| Chen, J | 1 |
| Min, S | 1 |
| Xie, F | 1 |
| Yang, J | 1 |
| Lin, CW | 1 |
| Lo, S | 1 |
| Perng, DS | 1 |
| Wu, DB | 1 |
| Lee, PH | 1 |
| Chang, YF | 1 |
| Kuo, PL | 1 |
| Yu, ML | 1 |
| Yuan, SS | 1 |
| Hsieh, YC | 1 |
| Jiang, Y | 1 |
| Gao, M | 1 |
| Wang, W | 1 |
| Lang, Y | 1 |
| Tong, Z | 1 |
| Wang, K | 1 |
| Zhang, H | 1 |
| Chen, G | 1 |
| Liu, M | 1 |
| Yao, Y | 1 |
| Xiao, X | 1 |
| Kayhan, N | 1 |
| Funke, B | 1 |
| Conzelmann, LO | 1 |
| Winkler, H | 1 |
| Hofer, S | 1 |
| Steppan, J | 1 |
| Schmidt, H | 1 |
| Bardenheuer, H | 1 |
| Vahl, CF | 1 |
| Weigand, MA | 1 |
| Williams, M | 1 |
| Kerkar, S | 1 |
| Tyburski, JG | 1 |
| Steffes, CP | 1 |
| Carlin, AM | 1 |
| Wilson, RF | 1 |
| Conlon, BA | 1 |
| Law, WR | 1 |
| Fitzgerald, RD | 1 |
| Martin, CM | 1 |
| Dietz, GE | 1 |
| Doig, GS | 1 |
| Potter, RF | 1 |
| Sibbald, WJ | 1 |
| Harbrecht, BG | 1 |
| Taylor, BS | 1 |
| Xu, Z | 1 |
| Ramalakshmi, S | 1 |
| Ganster, RW | 1 |
| Geller, DA | 1 |
16 other studies available for adenine and Blood Poisoning
| Article | Year |
|---|---|
Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Cecum; Disease Models, Animal; He | 2019 |
INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis.
Topics: Adenine; Animals; Anxiety; Cholic Acids; Cognitive Dysfunction; Cyclic AMP; Cyclic AMP Response Elem | 2021 |
Heat shock protein 70 expression protects against sepsis-associated cardiomyopathy by inhibiting autophagy.
Topics: Adenine; Animals; Autophagy; Cardiomyopathies; HSP70 Heat-Shock Proteins; Humans; Male; Models, Anim | 2021 |
X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Disease Models, Animal; Inflammas | 2020 |
Bruton's tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice.
Topics: Acute Kidney Injury; Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; B-Lymphocytes; Dendritic | 2021 |
Ibrutinib-associated necrotic nasal lesion and pulmonary infiltrates.
Topics: Adenine; Aged; Ecthyma; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Necrosis; Piperidine | 2021 |
Narciclasine attenuates sepsis-induced myocardial injury by modulating autophagy.
Topics: Adenine; Amaryllidaceae Alkaloids; Animals; Autophagy; Inflammation; Lipopolysaccharides; Male; MAP | 2021 |
Inhibition of autophagy with 3-methyladenine is protective in a lethal model of murine endotoxemia and polymicrobial sepsis.
Topics: Adenine; Animals; Autophagy; Carrier Proteins; Endotoxemia; Interleukin-6; Lipopolysaccharides; Male | 2018 |
Enhancing Autophagy Protects Against Sepsis-Induced Neuromuscular Dysfunction Associated with Qualitative Changes to Acetylcholine Receptors.
Topics: Adenine; Animals; Autophagy; Cecum; Ligation; Male; Punctures; Rats; Rats, Sprague-Dawley; Receptors | 2019 |
Complete activation of autophagic process attenuates liver injury and improves survival in septic mice.
Topics: Adenine; Amebicides; Animals; Anticonvulsants; Autophagy; Carbamazepine; Chloroquine; Liver; Lysosom | 2014 |
Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy.
Topics: Adenine; Animals; Autophagy; Cecum; Cell Line; Cytokines; Disease Models, Animal; Kidney; Lipopolysa | 2015 |
The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Female; Intestinal Absorption | 2008 |
The roles of cyclic adenosine monophosphate- and cyclic guanosine monophosphate-dependent protein kinase pathways in hydrogen peroxide-induced contractility of microvascular lung pericytes.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Analysis of Variance; Animals; Cell Survival; Cells, Cultured; | 2003 |
Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses.
Topics: Adaptor Proteins, Signal Transducing; Adenine; Adenosine Deaminase; Animals; Cells, Cultured; DNA-Bi | 2004 |
Transfusing red blood cells stored in citrate phosphate dextrose adenine-1 for 28 days fails to improve tissue oxygenation in rats.
Topics: Adenine; Animals; Anticoagulants; Blood Preservation; Citrates; Erythrocyte Transfusion; Glucose; He | 1997 |
cAMP inhibits inducible nitric oxide synthase expression and NF-kappaB-binding activity in cultured rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Ani | 2001 |