Page last updated: 2024-10-16

adenine and Blood Poisoning

adenine has been researched along with Blood Poisoning in 16 studies

Research Excerpts

ExcerptRelevanceReference
"This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats."8.02INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021)
" The aim of this study was to verify the hypothesis that adenosine deaminase-1 and cyclic guanosine monophosphate-stimulated phosphodiesterase inhibition by erythro-9-[2-hydroxyl-3-nonyl]-adenine could be beneficial in experimental endotoxicosis/sepsis."7.74The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. ( Bardenheuer, H; Conzelmann, LO; Funke, B; Hofer, S; Kayhan, N; Schmidt, H; Steppan, J; Vahl, CF; Weigand, MA; Winkler, H, 2008)
"Sinomenine (SIN) is a natural alkaloid extracted from Chinese medicinal plant Sinomenium acutum, and its hydrochloride salt (Sinomenine hydrochloride, SIN-HCl) is widely used to treat rheumatoid arthritis (RA)."5.42Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy. ( Chen, G; Gao, M; Jiang, Y; Lang, Y; Liu, M; Tong, Z; Wang, K; Wang, W; Xiao, X; Yao, Y; Zhang, H, 2015)
"This study demonstrates that INT-777 treatment reduced neuroinflammation and microglial cell activation, but improved cognitive impairment in the experimental sepsis rats."4.02INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis. ( Deng, S; Gao, Y; Gong, Y; Jin, P; Lenahan, C; Tan, J; Tian, M; Wang, Y; Wei, P; Wen, H; Zhao, F, 2021)
" The aim of this study was to verify the hypothesis that adenosine deaminase-1 and cyclic guanosine monophosphate-stimulated phosphodiesterase inhibition by erythro-9-[2-hydroxyl-3-nonyl]-adenine could be beneficial in experimental endotoxicosis/sepsis."3.74The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. ( Bardenheuer, H; Conzelmann, LO; Funke, B; Hofer, S; Kayhan, N; Schmidt, H; Steppan, J; Vahl, CF; Weigand, MA; Winkler, H, 2008)
"Sepsis is a life-threatening condition which affects multiple organs including the kidney."1.62Bruton's tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice. ( Ahmad, SF; Al-Harbi, NO; Alanazi, WA; Alqahtani, F; Alsanea, S; Attia, SM; Ibrahim, KE; Mahmood, HM; Nadeem, A, 2021)
"Sepsis is one of the most prevalent diseases in the world."1.51Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice. ( Al Zoubi, S; Chiazza, F; Coldewey, SM; Collino, M; Collotta, D; Martin, L; O'Riordan, CE; Purvis, GSD; Stiehler, L; Thiemermann, C; Wissuwa, B, 2019)
"Sinomenine (SIN) is a natural alkaloid extracted from Chinese medicinal plant Sinomenium acutum, and its hydrochloride salt (Sinomenine hydrochloride, SIN-HCl) is widely used to treat rheumatoid arthritis (RA)."1.42Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy. ( Chen, G; Gao, M; Jiang, Y; Lang, Y; Liu, M; Tong, Z; Wang, K; Wang, W; Xiao, X; Yao, Y; Zhang, H, 2015)
"Sepsis was induced by cecal ligation and puncture (CLP)."1.40Complete activation of autophagic process attenuates liver injury and improves survival in septic mice. ( Chang, YF; Hsieh, YC; Kuo, PL; Lee, PH; Lin, CW; Lo, S; Perng, DS; Wu, DB; Yu, ML; Yuan, SS, 2014)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's4 (25.00)29.6817
2010's5 (31.25)24.3611
2020's6 (37.50)2.80

Authors

AuthorsStudies
O'Riordan, CE2
Purvis, GSD2
Collotta, D2
Chiazza, F1
Wissuwa, B2
Al Zoubi, S1
Stiehler, L1
Martin, L1
Coldewey, SM2
Collino, M2
Thiemermann, C2
Jin, P1
Deng, S1
Tian, M1
Lenahan, C1
Wei, P1
Wang, Y1
Tan, J1
Wen, H1
Zhao, F1
Gao, Y1
Gong, Y1
Wang, X2
Zhu, Y1
Zhou, Q1
Yan, Y1
Qu, J1
Ye, H1
Krieg, N1
Sheikh, MH1
Ferreira Alves, G1
Mohammad, S1
Callender, LA1
Greaves, DR1
Nadeem, A1
Ahmad, SF1
Al-Harbi, NO1
Ibrahim, KE1
Alqahtani, F1
Alanazi, WA1
Mahmood, HM1
Alsanea, S1
Attia, SM1
Saling, C1
Feller, F1
Vikram, HR1
Tang, R1
Jia, L1
Li, Y1
Zheng, J1
Qi, P1
Li, Q1
Li, L1
Fei, X1
Zhang, Y1
Qi, C1
Hua, S1
Gong, F1
Fang, M1
Chen, J1
Min, S1
Xie, F1
Yang, J1
Lin, CW1
Lo, S1
Perng, DS1
Wu, DB1
Lee, PH1
Chang, YF1
Kuo, PL1
Yu, ML1
Yuan, SS1
Hsieh, YC1
Jiang, Y1
Gao, M1
Wang, W1
Lang, Y1
Tong, Z1
Wang, K1
Zhang, H1
Chen, G1
Liu, M1
Yao, Y1
Xiao, X1
Kayhan, N1
Funke, B1
Conzelmann, LO1
Winkler, H1
Hofer, S1
Steppan, J1
Schmidt, H1
Bardenheuer, H1
Vahl, CF1
Weigand, MA1
Williams, M1
Kerkar, S1
Tyburski, JG1
Steffes, CP1
Carlin, AM1
Wilson, RF1
Conlon, BA1
Law, WR1
Fitzgerald, RD1
Martin, CM1
Dietz, GE1
Doig, GS1
Potter, RF1
Sibbald, WJ1
Harbrecht, BG1
Taylor, BS1
Xu, Z1
Ramalakshmi, S1
Ganster, RW1
Geller, DA1

Other Studies

16 other studies available for adenine and Blood Poisoning

ArticleYear
Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Cecum; Disease Models, Animal; He

2019
INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis.
    Experimental neurology, 2021, Volume: 335

    Topics: Adenine; Animals; Anxiety; Cholic Acids; Cognitive Dysfunction; Cyclic AMP; Cyclic AMP Response Elem

2021
Heat shock protein 70 expression protects against sepsis-associated cardiomyopathy by inhibiting autophagy.
    Human & experimental toxicology, 2021, Volume: 40, Issue:5

    Topics: Adenine; Animals; Autophagy; Cardiomyopathies; HSP70 Heat-Shock Proteins; Humans; Male; Models, Anim

2021
X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Disease Models, Animal; Inflammas

2020
Bruton's tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice.
    International immunopharmacology, 2021, Volume: 90

    Topics: Acute Kidney Injury; Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; B-Lymphocytes; Dendritic

2021
Ibrutinib-associated necrotic nasal lesion and pulmonary infiltrates.
    BMJ case reports, 2021, Jan-19, Volume: 14, Issue:1

    Topics: Adenine; Aged; Ecthyma; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Necrosis; Piperidine

2021
Narciclasine attenuates sepsis-induced myocardial injury by modulating autophagy.
    Aging, 2021, 05-25, Volume: 13, Issue:11

    Topics: Adenine; Amaryllidaceae Alkaloids; Animals; Autophagy; Inflammation; Lipopolysaccharides; Male; MAP

2021
Inhibition of autophagy with 3-methyladenine is protective in a lethal model of murine endotoxemia and polymicrobial sepsis.
    Innate immunity, 2018, Volume: 24, Issue:4

    Topics: Adenine; Animals; Autophagy; Carrier Proteins; Endotoxemia; Interleukin-6; Lipopolysaccharides; Male

2018
Enhancing Autophagy Protects Against Sepsis-Induced Neuromuscular Dysfunction Associated with Qualitative Changes to Acetylcholine Receptors.
    Shock (Augusta, Ga.), 2019, Volume: 52, Issue:1

    Topics: Adenine; Animals; Autophagy; Cecum; Ligation; Male; Punctures; Rats; Rats, Sprague-Dawley; Receptors

2019
Complete activation of autophagic process attenuates liver injury and improves survival in septic mice.
    Shock (Augusta, Ga.), 2014, Volume: 41, Issue:3

    Topics: Adenine; Amebicides; Animals; Anticonvulsants; Autophagy; Carbamazepine; Chloroquine; Liver; Lysosom

2014
Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy.
    International journal of molecular sciences, 2015, Jan-23, Volume: 16, Issue:2

    Topics: Adenine; Animals; Autophagy; Cecum; Cell Line; Cytokines; Disease Models, Animal; Kidney; Lipopolysa

2015
The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation.
    Critical care (London, England), 2008, Volume: 12, Issue:5

    Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Female; Intestinal Absorption

2008
The roles of cyclic adenosine monophosphate- and cyclic guanosine monophosphate-dependent protein kinase pathways in hydrogen peroxide-induced contractility of microvascular lung pericytes.
    The Journal of trauma, 2003, Volume: 55, Issue:4

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Analysis of Variance; Animals; Cell Survival; Cells, Cultured;

2003
Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses.
    Clinical and experimental immunology, 2004, Volume: 138, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adenine; Adenosine Deaminase; Animals; Cells, Cultured; DNA-Bi

2004
Transfusing red blood cells stored in citrate phosphate dextrose adenine-1 for 28 days fails to improve tissue oxygenation in rats.
    Critical care medicine, 1997, Volume: 25, Issue:5

    Topics: Adenine; Animals; Anticoagulants; Blood Preservation; Citrates; Erythrocyte Transfusion; Glucose; He

1997
cAMP inhibits inducible nitric oxide synthase expression and NF-kappaB-binding activity in cultured rat hepatocytes.
    The Journal of surgical research, 2001, Volume: 99, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Ani

2001