adenine has been researched along with Benign Neoplasms, Brain in 39 studies
Excerpt | Relevance | Reference |
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"Malignant glioma is the most aggressive brain tumor." | 5.46 | Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. ( Chen, JT; Chen, RM; Cheng, BC; Chio, CC; Liu, SH; Yang, ST, 2017) |
"Quercetin can inhibit cell viability and induce autophagy of U87 and U251 glioma cells in a dose-dependent manner." | 5.43 | Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells. ( Bi, Y; Gao, D; Hou, X; Li, C; Liu, H; Liu, Y; Liu, Z; Peng, F; Shen, C; Shi, C; Wang, K; Wang, X; Wu, J; Zhang, J; Zhao, B; Zhao, S; Zheng, Z; Zhong, C; Zou, H, 2016) |
"Glioblastoma is the most aggressive cerebral gliomas." | 5.40 | Inhibition of autophagy enhances apoptosis induced by proteasome inhibitor bortezomib in human glioblastoma U87 and U251 cells. ( Feng, J; Leng, X; Li, J; Li, W; Lian, S; Wang, C; Wang, H; Zhang, X, 2014) |
"We present here a suicide therapy against malignant gliomas based on the transfer to tumor cells of a gene encoding a beta-glucosidase, linamarase (lis), which in the presence of the innocuous substrate linamarin (lin) produces cyanide, blocking the mitochondrial respiratory chain." | 3.74 | Glioma regression in vitro and in vivo by a suicide combined treatment. ( García-Escudero, V; Gargini, R; Izquierdo, M, 2008) |
"Glioblastoma is the most common malignant brain cancer in adults, with poor prognosis." | 2.58 | Targeting glioblastoma-derived pericytes improves chemotherapeutic outcome. ( Azevedo, PO; Birbrair, A; Guerra, DAP; Mintz, A; Paiva, AE; Sena, IFG; Silva, WN, 2018) |
" However, chromosome losses do not seem to directly cause the metabolic alterations by gene dosage effect." | 2.38 | [Chromosome abnormalities and adenine metabolism in human glial tumors]. ( Bardot, V; Delattre, JY; Dutrillaux, AM; Dutrillaux, B; Luccioni, C; Poisson, M; Vega, F, 1992) |
" The aim of the study was to define MerTK as a therapeutic target using an orally bioavailable inhibitor, UNC2025." | 1.48 | MerTK as a therapeutic target in glioblastoma. ( Bash, RE; Cohen, SM; Earp, HS; Ewend, MG; Frady, LN; Frye, SV; Gilbert, MR; Irvin, DM; Miller, CR; Schorzman, AN; Su, YT; Sulman, EP; Wang, X; Wu, J; Zamboni, WC, 2018) |
" Here we report the preclinical potential of a novel, orally bioavailable PI3K/mTOR dual inhibitor, DS7423 (hereafter DS), in in-vitro and in-vivo studies." | 1.46 | Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma. ( Gao, F; Hirota, Y; Kaul, I; Koul, D; Koyama, K; Nakayama, K; Saito, N; Setoguchi, M; Shiose, Y; Sulman, EP; Wang, S; Wu, S; Yung, WKA; Zheng, S, 2017) |
"Increased aspergillosis was observed with ibrutinib monotherapy and DA-TEDDi-R." | 1.46 | Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma. ( Bhaumik, S; Butman, JA; Ceribelli, M; Chen, L; Cole, DE; Desai, JV; Dunleavy, K; Gea-Banacloche, J; Heiss, J; Higham, CS; Jaffe, ES; Lionakis, MS; Little, RF; Lucas, N; Melani, C; Pittaluga, S; Roschewski, M; Schmitz, R; Staudt, LM; Steinberg, SM; Stetler-Stevenson, M; Thomas, CJ; Widemann, BC; Wilson, WH; Yang, Y, 2017) |
"Malignant glioma is the most common primary brain tumor in adults and has a poor prognosis." | 1.46 | High expression of Bruton's tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma. ( Hua, L; Liu, X; Niu, M; Shan, QQ; Tu, Y; Xie, P; Yu, R; Yue, C; Zhou, T, 2017) |
"Glioma is the most devastating cancer in the brain and has a poor prognosis in adults." | 1.46 | Isogambogenic Acid Inhibits the Growth of Glioma Through Activation of the AMPK-mTOR Pathway. ( Gao, M; Hou, X; Liu, H; Liu, Y; Peng, F; Shu, M; Wang, K; Wang, X; Xue, L; Ye, J; Zhao, B; Zhao, S; Zhao, W; Zhong, C, 2017) |
"Malignant glioma is the most aggressive brain tumor." | 1.46 | Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. ( Chen, JT; Chen, RM; Cheng, BC; Chio, CC; Liu, SH; Yang, ST, 2017) |
"Quercetin can inhibit cell viability and induce autophagy of U87 and U251 glioma cells in a dose-dependent manner." | 1.43 | Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells. ( Bi, Y; Gao, D; Hou, X; Li, C; Liu, H; Liu, Y; Liu, Z; Peng, F; Shen, C; Shi, C; Wang, K; Wang, X; Wu, J; Zhang, J; Zhao, B; Zhao, S; Zheng, Z; Zhong, C; Zou, H, 2016) |
"Inhibition of early steps of autophagy by 3-MA or Beclin 1 knockdown decreased the toxic effect of arsenic trioxide (ATO) in GBM cell lines." | 1.42 | Impact of autophagy inhibition at different stages on cytotoxic effect of autophagy inducer in glioblastoma cells. ( Bi, Y; Chen, X; Cho, K; Hou, X; Li, C; Liu, H; Liu, Y; Peng, F; Shen, C; Wang, K; Wang, X; Yang, Z; Zhang, J; Zhang, W; Zhang, X; Zhao, S; Zheng, Z; Zhong, C; Zou, H, 2015) |
"Glioblastoma is the most aggressive cerebral gliomas." | 1.40 | Inhibition of autophagy enhances apoptosis induced by proteasome inhibitor bortezomib in human glioblastoma U87 and U251 cells. ( Feng, J; Leng, X; Li, J; Li, W; Lian, S; Wang, C; Wang, H; Zhang, X, 2014) |
"Malignant gliomas are common primary tumors of the central nervous system." | 1.35 | Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells. ( Akiyama, Y; Bögler, O; Fujiwara, K; Kondo, S; Moritake, K; Shingu, T; Shinojima, N; Tamada, Y; Yokoyama, T, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (12.82) | 18.7374 |
1990's | 4 (10.26) | 18.2507 |
2000's | 5 (12.82) | 29.6817 |
2010's | 21 (53.85) | 24.3611 |
2020's | 4 (10.26) | 2.80 |
Authors | Studies |
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Guha, A | 1 |
Waris, S | 1 |
Nabors, LB | 1 |
Filippova, N | 1 |
Gorospe, M | 1 |
Kwan, T | 1 |
King, PH | 1 |
Castillo, JJ | 1 |
Treon, SP | 1 |
Halim, AA | 1 |
Alsayed, B | 1 |
Embarak, S | 1 |
Yaseen, T | 1 |
Dabbous, S | 1 |
Fontaine, O | 1 |
Dueluzeau, R | 1 |
Raibaud, P | 1 |
Chabanet, C | 1 |
Popoff, MR | 1 |
Badoual, J | 1 |
Gabilan, JC | 1 |
Andremont, A | 1 |
Gómez, L | 1 |
Andrés, S | 1 |
Sánchez, J | 1 |
Alonso, JM | 1 |
Rey, J | 1 |
López, F | 1 |
Jiménez, A | 1 |
Yan, Z | 1 |
Zhou, L | 1 |
Zhao, Y | 3 |
Wang, J | 7 |
Huang, L | 2 |
Hu, K | 1 |
Liu, H | 7 |
Wang, H | 5 |
Guo, Z | 1 |
Song, Y | 1 |
Huang, H | 4 |
Yang, R | 1 |
Owen, TW | 1 |
Al-Kaysi, RO | 1 |
Bardeen, CJ | 1 |
Cheng, Q | 1 |
Wu, S | 2 |
Cheng, T | 1 |
Zhou, X | 1 |
Wang, B | 4 |
Zhang, Q | 4 |
Wu, X | 2 |
Yao, Y | 3 |
Ochiai, T | 1 |
Ishiguro, H | 2 |
Nakano, R | 2 |
Kubota, Y | 2 |
Hara, M | 1 |
Sunada, K | 1 |
Hashimoto, K | 1 |
Kajioka, J | 1 |
Fujishima, A | 1 |
Jiao, J | 3 |
Gai, QY | 3 |
Wang, W | 2 |
Zang, YP | 2 |
Niu, LL | 2 |
Fu, YJ | 3 |
Wang, X | 8 |
Yao, LP | 1 |
Qin, QP | 1 |
Wang, ZY | 1 |
Liu, J | 5 |
Aleksic Sabo, V | 1 |
Knezevic, P | 1 |
Borges-Argáez, R | 1 |
Chan-Balan, R | 1 |
Cetina-Montejo, L | 1 |
Ayora-Talavera, G | 1 |
Sansores-Peraza, P | 1 |
Gómez-Carballo, J | 1 |
Cáceres-Farfán, M | 1 |
Jang, J | 1 |
Akin, D | 1 |
Bashir, R | 1 |
Yu, Z | 1 |
Zhu, J | 2 |
Jiang, H | 1 |
He, C | 2 |
Xiao, Z | 1 |
Xu, J | 2 |
Sun, Q | 1 |
Han, D | 1 |
Lei, H | 1 |
Zhao, K | 2 |
Zhu, L | 1 |
Li, X | 4 |
Fu, H | 2 |
Wilson, BK | 1 |
Step, DL | 1 |
Maxwell, CL | 1 |
Gifford, CA | 1 |
Richards, CJ | 1 |
Krehbiel, CR | 1 |
Warner, JM | 1 |
Doerr, AJ | 1 |
Erickson, GE | 1 |
Guretzky, JA | 1 |
Rasby, RJ | 1 |
Watson, AK | 1 |
Klopfenstein, TJ | 1 |
Sun, Y | 4 |
Liu, Z | 4 |
Pham, TD | 1 |
Lee, BK | 1 |
Yang, FC | 1 |
Wu, KH | 1 |
Lin, WP | 1 |
Hu, MK | 1 |
Lin, L | 3 |
Shao, J | 1 |
Sun, M | 1 |
Xu, G | 1 |
Zhang, X | 8 |
Xu, N | 1 |
Wang, R | 2 |
Liu, S | 1 |
He, H | 1 |
Dong, X | 2 |
Yang, M | 2 |
Yang, Q | 1 |
Duan, S | 1 |
Yu, Y | 3 |
Han, J | 2 |
Zhang, C | 4 |
Chen, L | 3 |
Yang, X | 1 |
Li, W | 4 |
Wang, T | 2 |
Campbell, DA | 1 |
Gao, K | 1 |
Zager, RA | 1 |
Johnson, ACM | 1 |
Guillem, A | 1 |
Keyser, J | 1 |
Singh, B | 1 |
Steubl, D | 1 |
Schneider, MP | 1 |
Meiselbach, H | 1 |
Nadal, J | 1 |
Schmid, MC | 1 |
Saritas, T | 1 |
Krane, V | 1 |
Sommerer, C | 1 |
Baid-Agrawal, S | 1 |
Voelkl, J | 1 |
Kotsis, F | 1 |
Köttgen, A | 1 |
Eckardt, KU | 1 |
Scherberich, JE | 1 |
Li, H | 4 |
Yao, L | 2 |
Sun, L | 4 |
Zhu, Z | 1 |
Naren, N | 1 |
Zhang, XX | 2 |
Gentile, GL | 1 |
Rupert, AS | 1 |
Carrasco, LI | 1 |
Garcia, EM | 1 |
Kumar, NG | 1 |
Walsh, SW | 1 |
Jefferson, KK | 1 |
Guest, RL | 1 |
Samé Guerra, D | 1 |
Wissler, M | 1 |
Grimm, J | 1 |
Silhavy, TJ | 1 |
Lee, JH | 2 |
Yoo, JS | 1 |
Kim, Y | 1 |
Kim, JS | 2 |
Lee, EJ | 1 |
Roe, JH | 1 |
Delorme, M | 1 |
Bouchard, PA | 1 |
Simon, M | 1 |
Simard, S | 1 |
Lellouche, F | 1 |
D'Urzo, KA | 1 |
Mok, F | 1 |
D'Urzo, AD | 1 |
Koneru, B | 1 |
Lopez, G | 1 |
Farooqi, A | 1 |
Conkrite, KL | 1 |
Nguyen, TH | 1 |
Macha, SJ | 1 |
Modi, A | 1 |
Rokita, JL | 1 |
Urias, E | 1 |
Hindle, A | 1 |
Davidson, H | 1 |
Mccoy, K | 1 |
Nance, J | 1 |
Yazdani, V | 1 |
Irwin, MS | 1 |
Yang, S | 1 |
Wheeler, DA | 1 |
Maris, JM | 1 |
Diskin, SJ | 1 |
Reynolds, CP | 1 |
Abhilash, L | 1 |
Kalliyil, A | 1 |
Sheeba, V | 1 |
Hartley, AM | 2 |
Meunier, B | 2 |
Pinotsis, N | 1 |
Maréchal, A | 2 |
Xu, JY | 1 |
Genko, N | 1 |
Haraux, F | 1 |
Rich, PR | 1 |
Kamalanathan, M | 1 |
Doyle, SM | 1 |
Xu, C | 1 |
Achberger, AM | 1 |
Wade, TL | 1 |
Schwehr, K | 1 |
Santschi, PH | 1 |
Sylvan, JB | 1 |
Quigg, A | 1 |
Leong, W | 1 |
Xu, W | 2 |
Gao, S | 1 |
Zhai, X | 1 |
Wang, C | 3 |
Gilson, E | 1 |
Ye, J | 2 |
Lu, Y | 1 |
Yan, R | 1 |
Zhang, Y | 6 |
Hu, Z | 1 |
You, Q | 1 |
Cai, Q | 1 |
Yang, D | 1 |
Gu, S | 1 |
Dai, H | 1 |
Zhao, X | 1 |
Gui, C | 1 |
Gui, J | 1 |
Wu, PK | 1 |
Hong, SK | 1 |
Starenki, D | 1 |
Oshima, K | 1 |
Shao, H | 1 |
Gestwicki, JE | 1 |
Tsai, S | 1 |
Park, JI | 1 |
Wang, Y | 8 |
Zhao, R | 1 |
Gu, Z | 1 |
Dong, C | 2 |
Guo, G | 1 |
Li, L | 4 |
Barrett, HE | 1 |
Meester, EJ | 1 |
van Gaalen, K | 1 |
van der Heiden, K | 1 |
Krenning, BJ | 1 |
Beekman, FJ | 1 |
de Blois, E | 1 |
de Swart, J | 1 |
Verhagen, HJ | 1 |
Maina, T | 1 |
Nock, BA | 1 |
Norenberg, JP | 1 |
de Jong, M | 1 |
Gijsen, FJH | 1 |
Bernsen, MR | 1 |
Martínez-Milla, J | 1 |
Galán-Arriola, C | 1 |
Carnero, M | 1 |
Cobiella, J | 1 |
Pérez-Camargo, D | 1 |
Bautista-Hernández, V | 1 |
Rigol, M | 1 |
Solanes, N | 1 |
Villena-Gutierrez, R | 1 |
Lobo, M | 1 |
Mateo, J | 1 |
Vilchez-Tschischke, JP | 1 |
Salinas, B | 1 |
Cussó, L | 1 |
López, GJ | 1 |
Fuster, V | 1 |
Desco, M | 1 |
Sanchez-González, J | 1 |
Ibanez, B | 1 |
van den Berg, P | 1 |
Schweitzer, DH | 1 |
van Haard, PMM | 1 |
Geusens, PP | 1 |
van den Bergh, JP | 1 |
Zhu, X | 1 |
Huang, X | 2 |
Xu, H | 2 |
Yang, G | 2 |
Lin, Z | 1 |
Salem, HF | 1 |
Nafady, MM | 1 |
Kharshoum, RM | 1 |
Abd El-Ghafar, OA | 1 |
Farouk, HO | 1 |
Domiciano, D | 1 |
Nery, FC | 1 |
de Carvalho, PA | 1 |
Prudente, DO | 1 |
de Souza, LB | 1 |
Chalfun-Júnior, A | 1 |
Paiva, R | 1 |
Marchiori, PER | 1 |
Lu, M | 2 |
An, Z | 1 |
Jiang, J | 2 |
Li, J | 8 |
Du, S | 1 |
Zhou, H | 1 |
Cui, J | 1 |
Wu, W | 1 |
Liu, Y | 10 |
Song, J | 1 |
Lian, Q | 1 |
Uddin Ahmad, Z | 1 |
Gang, DD | 1 |
Konggidinata, MI | 1 |
Gallo, AA | 1 |
Zappi, ME | 1 |
Yang, TWW | 1 |
Johari, Y | 1 |
Burton, PR | 1 |
Earnest, A | 1 |
Shaw, K | 1 |
Hare, JL | 1 |
Brown, WA | 1 |
Kim, GA | 1 |
Han, S | 1 |
Choi, GH | 1 |
Choi, J | 1 |
Lim, YS | 1 |
Gallo, A | 1 |
Cancelli, C | 1 |
Ceron, E | 1 |
Covino, M | 1 |
Capoluongo, E | 1 |
Pocino, K | 1 |
Ianiro, G | 1 |
Cammarota, G | 1 |
Gasbarrini, A | 1 |
Montalto, M | 1 |
Somasundar, Y | 1 |
Lu, IC | 1 |
Mills, MR | 1 |
Qian, LY | 1 |
Olivares, X | 1 |
Ryabov, AD | 1 |
Collins, TJ | 1 |
Zhao, L | 1 |
Doddipatla, S | 1 |
Thomas, AM | 1 |
Nikolayev, AA | 1 |
Galimova, GR | 1 |
Azyazov, VN | 1 |
Mebel, AM | 1 |
Kaiser, RI | 1 |
Guo, S | 1 |
Yang, P | 1 |
Yu, X | 2 |
Wu, Y | 2 |
Zhang, H | 3 |
Yu, B | 2 |
Han, B | 1 |
George, MW | 1 |
Moor, MB | 1 |
Bonny, O | 1 |
Langenberg, E | 1 |
Paik, H | 1 |
Smith, EH | 1 |
Nair, HP | 1 |
Hanke, I | 1 |
Ganschow, S | 1 |
Catalan, G | 1 |
Domingo, N | 1 |
Schlom, DG | 1 |
Assefa, MK | 1 |
Wu, G | 2 |
Hayton, TW | 1 |
Becker, B | 1 |
Enikeev, D | 1 |
Netsch, C | 1 |
Gross, AJ | 1 |
Laukhtina, E | 1 |
Glybochko, P | 1 |
Rapoport, L | 1 |
Herrmann, TRW | 1 |
Taratkin, M | 1 |
Dai, W | 1 |
Shi, J | 2 |
Carreno, J | 1 |
Kloner, RA | 1 |
Pickersgill, NA | 1 |
Vetter, JM | 1 |
Kim, EH | 1 |
Cope, SJ | 1 |
Du, K | 1 |
Venkatesh, R | 1 |
Giardina, JD | 1 |
Saad, NES | 1 |
Bhayani, SB | 1 |
Figenshau, RS | 1 |
Eriksson, J | 1 |
Landfeldt, E | 1 |
Ireland, S | 1 |
Jackson, C | 1 |
Wyatt, E | 1 |
Gaudig, M | 1 |
Stancill, JS | 1 |
Happ, JT | 1 |
Broniowska, KA | 1 |
Hogg, N | 1 |
Corbett, JA | 1 |
Tang, LF | 1 |
Bi, YL | 1 |
Fan, Y | 2 |
Sun, YB | 1 |
Wang, AL | 1 |
Xiao, BH | 1 |
Wang, LF | 1 |
Qiu, SW | 1 |
Guo, SW | 1 |
Wáng, YXJ | 1 |
Sun, J | 2 |
Chu, S | 1 |
Pan, Q | 1 |
Li, D | 2 |
Zheng, S | 3 |
Ma, L | 1 |
Wang, L | 3 |
Hu, T | 1 |
Wang, F | 1 |
Han, Z | 1 |
Yin, Z | 1 |
Ge, X | 1 |
Xie, K | 1 |
Lei, P | 1 |
Dias-Santagata, D | 1 |
Lennerz, JK | 1 |
Sadow, PM | 1 |
Frazier, RP | 1 |
Govinda Raju, S | 1 |
Henry, D | 1 |
Chung, T | 1 |
Kherani, J | 1 |
Rothenberg, SM | 1 |
Wirth, LJ | 1 |
Marti, CN | 1 |
Choi, NG | 1 |
Bae, SJ | 1 |
Ni, L | 1 |
Luo, X | 1 |
Dai, T | 1 |
Yang, Y | 4 |
Lee, R | 1 |
Fleischer, AS | 1 |
Wemhoff, AP | 1 |
Ford, CR | 1 |
Kleppinger, EL | 1 |
Helms, K | 1 |
Bush, AA | 1 |
Luna-Abanto, J | 1 |
García Ruiz, L | 1 |
Laura Martinez, J | 1 |
Álvarez Larraondo, M | 1 |
Villoslada Terrones, V | 1 |
Dukic, L | 1 |
Maric, N | 1 |
Simundic, AM | 1 |
Chogtu, B | 1 |
Ommurugan, B | 1 |
Thomson, SR | 1 |
Kalthur, SG | 1 |
Benidir, M | 1 |
El Massoudi, S | 1 |
El Ghadraoui, L | 1 |
Lazraq, A | 1 |
Benjelloun, M | 1 |
Errachidi, F | 1 |
Cassar, M | 1 |
Law, AD | 1 |
Chow, ES | 1 |
Giebultowicz, JM | 1 |
Kretzschmar, D | 1 |
Salonurmi, T | 1 |
Nabil, H | 1 |
Ronkainen, J | 1 |
Hyötyläinen, T | 1 |
Hautajärvi, H | 1 |
Savolainen, MJ | 1 |
Tolonen, A | 1 |
Orešič, M | 1 |
Känsäkoski, P | 1 |
Rysä, J | 1 |
Hakkola, J | 1 |
Hukkanen, J | 1 |
Zhu, N | 1 |
Li, Y | 5 |
Du, Q | 1 |
Hao, P | 1 |
Cao, X | 1 |
Li, CX | 1 |
Zhao, S | 4 |
Luo, XM | 1 |
Feng, JX | 1 |
Gonzalez-Cotto, M | 1 |
Guo, L | 1 |
Karwan, M | 1 |
Sen, SK | 1 |
Barb, J | 1 |
Collado, CJ | 1 |
Elloumi, F | 1 |
Palmieri, EM | 1 |
Boelte, K | 1 |
Kolodgie, FD | 1 |
Finn, AV | 1 |
Biesecker, LG | 1 |
McVicar, DW | 1 |
Qu, F | 1 |
Deng, Z | 1 |
Xie, Y | 2 |
Tang, J | 3 |
Chen, Z | 3 |
Luo, W | 1 |
Xiong, D | 1 |
Zhao, D | 1 |
Fang, J | 1 |
Zhou, Z | 1 |
Niu, PP | 1 |
Song, B | 1 |
Xu, YM | 1 |
Zhang, Z | 2 |
Qiu, N | 1 |
Yin, J | 1 |
Zhang, J | 6 |
Guo, W | 1 |
Liu, M | 2 |
Liu, T | 2 |
Chen, D | 5 |
Luo, K | 1 |
He, Z | 2 |
Zheng, G | 1 |
Xu, F | 1 |
Sun, W | 1 |
Yin, F | 1 |
van Hest, JCM | 1 |
Du, L | 2 |
Shi, X | 1 |
Kang, S | 1 |
Duan, W | 1 |
Zhang, S | 2 |
Feng, J | 3 |
Qi, N | 1 |
Shen, G | 1 |
Ren, H | 1 |
Shang, Q | 1 |
Zhao, W | 3 |
Yang, Z | 3 |
Jiang, X | 2 |
Alame, M | 1 |
Cornillot, E | 1 |
Cacheux, V | 1 |
Tosato, G | 1 |
Four, M | 1 |
De Oliveira, L | 1 |
Gofflot, S | 1 |
Delvenne, P | 1 |
Turtoi, E | 1 |
Cabello-Aguilar, S | 1 |
Nishiyama, M | 1 |
Turtoi, A | 1 |
Costes-Martineau, V | 1 |
Colinge, J | 1 |
Guo, Q | 1 |
Quan, M | 1 |
Dong, J | 1 |
Bai, J | 1 |
Han, R | 1 |
Cai, Y | 1 |
Lv, YQ | 1 |
Chen, Q | 2 |
Lyu, HD | 1 |
Deng, L | 1 |
Zhou, D | 1 |
Xiao, X | 1 |
De Langhe, S | 1 |
Billadeau, DD | 1 |
Lou, Z | 1 |
Zhang, JS | 1 |
Xue, Z | 1 |
Shen, XD | 1 |
Gao, F | 2 |
Busuttil, RW | 1 |
Kupiec-Weglinski, JW | 1 |
Ji, H | 1 |
Otano, I | 1 |
Alvarez, M | 1 |
Minute, L | 1 |
Ochoa, MC | 1 |
Migueliz, I | 1 |
Molina, C | 1 |
Azpilikueta, A | 1 |
de Andrea, CE | 1 |
Etxeberria, I | 1 |
Sanmamed, MF | 1 |
Teijeira, Á | 1 |
Berraondo, P | 1 |
Melero, I | 1 |
Zhong, Z | 1 |
Xie, X | 1 |
Yu, Q | 1 |
Zhou, C | 1 |
Liu, C | 2 |
Liu, W | 1 |
Chen, W | 1 |
Yin, Y | 1 |
Li, CW | 1 |
Hsu, JL | 1 |
Zhou, Q | 1 |
Hu, B | 1 |
Fu, P | 1 |
Atyah, M | 1 |
Ma, Q | 2 |
Xu, Y | 1 |
Dong, Q | 1 |
Hung, MC | 1 |
Ren, N | 1 |
Huang, P | 1 |
Liao, R | 1 |
Chen, X | 4 |
Cao, Q | 1 |
Yuan, X | 2 |
Nie, W | 1 |
Yang, J | 2 |
Shao, B | 1 |
Ma, X | 1 |
Bi, Z | 1 |
Liang, X | 1 |
Tie, Y | 1 |
Mo, F | 1 |
Xie, D | 1 |
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Zhuang, WZ | 1 |
Long, LM | 1 |
Ji, WJ | 1 |
Liang, ZQ | 1 |
Kanai, R | 1 |
Zaupa, C | 1 |
Sgubin, D | 1 |
Antoszczyk, SJ | 1 |
Martuza, RL | 1 |
Wakimoto, H | 1 |
Rabkin, SD | 1 |
Komata, T | 1 |
Kanzawa, T | 2 |
Nashimoto, T | 1 |
Aoki, H | 1 |
Endo, S | 1 |
Nameta, M | 1 |
Takahashi, H | 1 |
Yamamoto, T | 1 |
Tanaka, R | 1 |
Ito, H | 1 |
Daido, S | 1 |
Kondo, Y | 1 |
García-Escudero, V | 1 |
Gargini, R | 1 |
Izquierdo, M | 1 |
Levitt, R | 1 |
Buckner, JC | 1 |
Cascino, TL | 1 |
Burch, PA | 1 |
Morton, RF | 1 |
Westberg, MW | 1 |
Goldberg, RM | 1 |
Gallagher, JG | 1 |
O'Fallon, JR | 1 |
Scheithauer, BW | 1 |
Lewin, E | 1 |
Louis, DN | 1 |
von Deimling, A | 1 |
Seizinger, BR | 1 |
Bardot, V | 1 |
Dutrillaux, AM | 1 |
Luccioni, C | 1 |
Poisson, M | 1 |
Delattre, JY | 1 |
Vega, F | 1 |
Dutrillaux, B | 1 |
Balzarini, J | 1 |
Sobis, H | 1 |
Naesens, L | 1 |
Vandeputte, M | 1 |
Goth, R | 1 |
Rajewsky, MF | 1 |
Shimizu, H | 2 |
Tanaka, S | 1 |
Suzuki, T | 1 |
Matsukado, Y | 2 |
Kodama, T | 1 |
Kleihues, P | 1 |
Margison, GP | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Clinical Efficacy and Safety of IBER Salvage Treatment Followed by Ibrutinib Maintenance for Transplant-ineligible Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL): a Multicenter, Single-arm, Prospective Phase II Study[NCT04066920] | Phase 2 | 30 participants (Anticipated) | Interventional | 2019-10-01 | Not yet recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
6 reviews available for adenine and Benign Neoplasms, Brain
Article | Year |
---|---|
The versatile role of HuR in Glioblastoma and its potential as a therapeutic target for a multi-pronged attack.
Topics: Adenine; Brain Neoplasms; ELAV-Like Protein 1; Glioblastoma; Humans; Neovascularization, Pathologic; | 2022 |
How we manage Bing-Neel syndrome.
Topics: Adenine; Amino Acid Substitution; Brain Neoplasms; Humans; Magnetic Resonance Imaging; Mutation, Mis | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Modulation of untranslated region alternative polyadenylation in glioma tumorigenesis.
Topics: 3' Untranslated Regions; Adenine; Animals; Brain Neoplasms; Carcinogenesis; Glioma; Humans; Polyaden | 2021 |
Targeting glioblastoma-derived pericytes improves chemotherapeutic outcome.
Topics: Adenine; Animals; Blood-Brain Barrier; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Mice; P | 2018 |
[Chromosome abnormalities and adenine metabolism in human glial tumors].
Topics: Adenine; Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromos | 1992 |
2 trials available for adenine and Benign Neoplasms, Brain
Article | Year |
---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Phase II study of amonafide in patients with recurrent glioma.
Topics: Adenine; Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; | 1995 |
32 other studies available for adenine and Benign Neoplasms, Brain
Article | Year |
---|---|
Pimozide Suppresses the Growth of Brain Tumors by Targeting STAT3-Mediated Autophagy.
Topics: Adenine; Animals; Antineoplastic Agents; Antipsychotic Agents; Autophagy; Autophagy-Related Protein | 2020 |
N6-methyladenine-related genes affect biological behavior and the prognosis of glioma.
Topics: Adenine; Adult; Brain Neoplasms; China; Databases, Nucleic Acid; DNA Methylation; Epigenesis, Geneti | 2021 |
Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma.
Topics: Adenine; Animals; Antineoplastic Agents; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Ce | 2017 |
Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Animals; Aspergillosis; Brain | 2017 |
MerTK as a therapeutic target in glioblastoma.
Topics: Adenine; Animals; Brain Neoplasms; c-Mer Tyrosine Kinase; Cell Line, Tumor; Gene Expression Regulati | 2018 |
High expression of Bruton's tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movem | 2017 |
Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy.
Topics: Adenine; Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Glioma; Humans; Mice | 2017 |
Isogambogenic Acid Inhibits the Growth of Glioma Through Activation of the AMPK-mTOR Pathway.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Brain | 2017 |
N
Topics: Adenine; Adult; Aged; AlkB Homolog 1, Histone H2a Dioxygenase; Animals; Astrocytes; Brain Neoplasms; | 2018 |
Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation.
Topics: Adenine; Animals; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Chromones; Down-Regulation; | 2019 |
Inhibition of autophagy enhances apoptosis induced by proteasome inhibitor bortezomib in human glioblastoma U87 and U251 cells.
Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 7; Boronic A | 2014 |
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
Topics: Adenine; Apoptosis; Autophagy; Autophagy-Related Protein 5; Brain Neoplasms; Cell Line, Tumor; Gliom | 2015 |
Impact of autophagy inhibition at different stages on cytotoxic effect of autophagy inducer in glioblastoma cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenica | 2015 |
Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 3; Caspases, Initiato | 2015 |
Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells.
Topics: Adenine; Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chloroquine; Gli | 2016 |
Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes.
Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Animals; Brain Neoplasms; Cell Line, Tumo | 2016 |
Mantle Cell Lymphoma with Central Nervous System Involvement Simulating Bilateral Subdural Hematomas.
Topics: Adenine; Aged; Antineoplastic Agents; Brain Neoplasms; Diagnosis, Differential; Hematoma, Subdural; | 2017 |
Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway.
Topics: Adenine; Antimutagenic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 3; Cell Hypoxia; Cell | 2017 |
Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells.
Topics: Adenine; Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Benzamides; Brain Neoplasms; | 2009 |
Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain | 2009 |
Rapamycin induces differentiation of glioma stem/progenitor cells by activating autophagy.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Autophagy; Brain Neoplasms; Cell Differentiation; Cel | 2011 |
Effect of γ34.5 deletions on oncolytic herpes simplex virus activity in brain tumors.
Topics: Adenine; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain Neoplasms; Cell Line; Ch | 2012 |
Mild heat shock induces autophagic growth arrest, but not apoptosis in U251-MG and U87-MG human malignant glioma cells.
Topics: Adenine; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Enzyme | 2004 |
Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells.
Topics: Adenine; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; DNA Damage; Enzyme Inhibitors; Gene Expr | 2005 |
Glioma regression in vitro and in vivo by a suicide combined treatment.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Adenine; Animals; Brain Neop | 2008 |
Effects of phenytoin on the release of 14C-adenine derivatives.
Topics: Adenine; Animals; Astrocytoma; Brain Neoplasms; Carbamazepine; Cells, Cultured; Cerebral Cortex; Hyp | 1977 |
A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens.
Topics: Adenine; Astrocytoma; Brain Neoplasms; Chromosome Deletion; Cytidine; DNA, Neoplasm; Glioma; Heteroz | 1992 |
Inhibitory effects of 9-(2-phosphonylmethoxyethyl)adenine and 3'-azido-2',3'-dideoxythymidine on tumor development in mice inoculated intracerebrally with Moloney murine sarcoma virus.
Topics: Adenine; Animals; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; D | 1990 |
Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues.
Topics: Adenine; Alkylation; Animals; Autoradiography; Brain Chemistry; Brain Neoplasms; Carbon Radioisotope | 1974 |
The response of human cerebrum adenyl cyclase to biogenic amines.
Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain Neoplasms; C | 1971 |
The cyclic AMP system of human brain.
Topics: Adenine; Adenosine; Adenylyl Cyclases; Adult; Aged; Brain; Brain Chemistry; Brain Neoplasms; Carbon | 1973 |
Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.
Topics: Adenine; Animals; Brain; Brain Neoplasms; Carcinogens; DNA; DNA Repair; Female; Guanine; Kidney; Kid | 1974 |