adenine has been researched along with Autoimmune Disease in 22 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "While opportunistic infections and viral reactivations occur with both ibrutinib and idelalisib, these complications are less common and less severe with ibrutinib, especially when used as monotherapy without additional immunosuppressive agents." | 2.58 | Immunological changes with kinase inhibitor therapy for chronic lymphocytic leukemia. ( Pleyer, C; Sun, C; Wiestner, A, 2018) |
| "The clinical course of chronic lymphocytic leukemia (CLL) is often complicated by autoimmune cytopenia (AIC)." | 1.51 | [Improvement of autoimmune cytopenia with ibrutinib in a chronic lymphocytic leukemia patient complicated by monoclonal immunoglobulin deposition disease]. ( Hara, S; Ishikawa, T; Nakamura, M; Yamashita, D; Yoshioka, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, M | 1 |
| Yoshioka, S | 1 |
| Yamashita, D | 1 |
| Hara, S | 1 |
| Ishikawa, T | 1 |
| Vitale, C | 2 |
| Salvetti, C | 1 |
| Griggio, V | 1 |
| Porrazzo, M | 1 |
| Schiattone, L | 1 |
| Zamprogna, G | 1 |
| Visentin, A | 1 |
| Vassallo, F | 1 |
| Cassin, R | 1 |
| Rigolin, GM | 1 |
| Murru, R | 1 |
| Laurenti, L | 1 |
| Rivela, P | 1 |
| Marchetti, M | 1 |
| Pennese, E | 1 |
| Gentile, M | 1 |
| Boccellato, E | 1 |
| Perutelli, F | 1 |
| Montalbano, MC | 1 |
| De Paoli, L | 1 |
| Reda, G | 1 |
| Orsucci, L | 1 |
| Trentin, L | 1 |
| Cuneo, A | 1 |
| Tedeschi, A | 1 |
| Scarfò, L | 1 |
| Gaidano, G | 1 |
| Mauro, FR | 1 |
| Foà, R | 1 |
| Boccadoro, M | 1 |
| Coscia, M | 1 |
| Tang, L | 1 |
| Wei, X | 1 |
| Li, T | 1 |
| Chen, Y | 1 |
| Dai, Z | 1 |
| Lu, C | 1 |
| Zheng, G | 1 |
| Ma, WH | 1 |
| Zhang, XG | 1 |
| Guo, LL | 1 |
| Zhang, JB | 1 |
| Wei, FT | 1 |
| Lu, QH | 1 |
| Du, H | 1 |
| Kong, YR | 1 |
| Wang, X | 1 |
| Xu, DL | 1 |
| Zhang, Z | 1 |
| Zhang, D | 1 |
| Liu, Y | 1 |
| Yang, D | 1 |
| Ran, F | 1 |
| Wang, ML | 1 |
| Zhao, G | 1 |
| Pleyer, C | 1 |
| Wiestner, A | 2 |
| Sun, C | 1 |
| Wanner, D | 1 |
| Bohn, JP | 1 |
| Rudzki, J | 1 |
| Stockhammer, G | 1 |
| Steurer, M | 1 |
| Hampel, PJ | 1 |
| Larson, MC | 1 |
| Kabat, B | 1 |
| Call, TG | 1 |
| Ding, W | 1 |
| Kenderian, SS | 1 |
| Bowen, D | 1 |
| Boysen, J | 1 |
| Schwager, SM | 1 |
| Leis, JF | 1 |
| Chanan-Khan, AA | 1 |
| Muchtar, E | 1 |
| Hanson, CA | 1 |
| Slager, SL | 1 |
| Kay, NE | 1 |
| Chaffee, KG | 1 |
| Shanafelt, TD | 1 |
| Parikh, SA | 1 |
| Quinquenel, A | 1 |
| Godet, S | 1 |
| Dartigeas, C | 1 |
| Ysebaert, L | 1 |
| Dupuis, J | 1 |
| Ohanyan, H | 1 |
| Collignon, A | 1 |
| Gilardin, L | 1 |
| Lepretre, S | 1 |
| Dilhuydy, MS | 1 |
| Vignon, M | 1 |
| de Guibert, S | 1 |
| Dmytruk, N | 1 |
| Durot, E | 1 |
| Ghez, D | 1 |
| Roos Weil, D | 1 |
| Béné, MC | 1 |
| Toussaint, E | 1 |
| Merabet, F | 1 |
| Lévy, V | 1 |
| Delmer, A | 1 |
| Aurran, T | 1 |
| Burger, JA | 2 |
| Buggy, JJ | 2 |
| Yuan, J | 1 |
| Yu, M | 1 |
| Li, HH | 1 |
| Long, Q | 1 |
| Liang, W | 1 |
| Wen, S | 1 |
| Wang, M | 1 |
| Guo, HP | 1 |
| Cheng, X | 1 |
| Liao, YH | 1 |
| Xing, L | 1 |
| Huang, A | 1 |
| Viganò, M | 1 |
| Mangia, G | 1 |
| Lampertico, P | 1 |
| Kokhaei, P | 1 |
| Jadidi-Niaragh, F | 1 |
| Sotoodeh Jahromi, A | 1 |
| Osterborg, A | 1 |
| Mellstedt, H | 1 |
| Hojjat-Farsangi, M | 1 |
| Ahn, IE | 1 |
| Sivina, M | 1 |
| Ferrajoli, A | 1 |
| Wierda, WG | 1 |
| Estrov, Z | 1 |
| Konoplev, SN | 1 |
| Jain, N | 1 |
| O'Brien, S | 1 |
| Farooqui, M | 1 |
| Keating, MJ | 1 |
| Schliffke, S | 1 |
| Akyüz, N | 1 |
| Ford, CT | 1 |
| Mährle, T | 1 |
| Thenhausen, T | 1 |
| Krohn-Grimberghe, A | 1 |
| Knop, S | 1 |
| Bokemeyer, C | 1 |
| Binder, M | 1 |
| Hayashi, T | 1 |
| Gray, CS | 1 |
| Chan, M | 1 |
| Tawatao, RI | 1 |
| Ronacher, L | 1 |
| McGargill, MA | 1 |
| Datta, SK | 1 |
| Carson, DA | 1 |
| Corr, M | 1 |
| Honigberg, LA | 1 |
| Smith, AM | 1 |
| Sirisawad, M | 1 |
| Verner, E | 1 |
| Loury, D | 1 |
| Chang, B | 1 |
| Li, S | 1 |
| Pan, Z | 1 |
| Thamm, DH | 1 |
| Miller, RA | 1 |
| Lawson, BR | 1 |
| Manenkova, Y | 1 |
| Ahamed, J | 1 |
| Chen, X | 1 |
| Zou, JP | 1 |
| Baccala, R | 1 |
| Theofilopoulos, AN | 1 |
| Yuan, C | 1 |
| Ahmad, J | 1 |
| Ashok, BT | 1 |
| Ali, R | 1 |
| Cowan, DH | 1 |
| Graham, RC | 1 |
| Lawley, PD | 1 |
| Harris, G | 1 |
| Phillips, E | 1 |
| Irving, W | 1 |
| Colaço, CB | 1 |
| Lydyard, PM | 1 |
| Roitt, IM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of BCR Inhibitors in the Treatment of Autoimmune Cytopenias Associated With Chronic Lymphocytic Leukemia (CLL): A Retrospective Analysis of the French Innovative Leukemia Organization (FILO)[NCT03469895] | 40 participants (Actual) | Observational | 2017-07-21 | Active, not recruiting | |||
| Phase III Randomized Study to Investigate the Use of Acalabrutinib in the Treatment of Patients With Early Stage CLL With High Risk of Early Disease Progression[NCT04178798] | Phase 3 | 22 participants (Actual) | Interventional | 2019-12-09 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for adenine and Autoimmune Disease
| Article | Year |
|---|---|
Emerging Perspectives of RNA
Topics: Adaptive Immunity; Adenine; Autoimmune Diseases; Dendritic Cells; Humans; Immunity, Innate; Methylat | 2021 |
Targeting Bruton's tyrosine kinase for the treatment of B cell associated malignancies and autoimmune diseases: Preclinical and clinical developments of small molecule inhibitors.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Autoimmune Diseases; B | 2018 |
Immunological changes with kinase inhibitor therapy for chronic lymphocytic leukemia.
Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Autoimmunity; B-Lympho | 2018 |
Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765).
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Autoimmune Diseases; B-Lymphocytes; Drug Eval | 2013 |
Bruton's TK inhibitors: structural insights and evolution of clinical candidates.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Autoimmune Diseases; Clinical Trials as Topic | 2014 |
Management of patients with overt or resolved hepatitis B virus infection undergoing rituximab therapy.
Topics: Adenine; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Monoclonal, Murine- | 2014 |
Ibrutinib-A double-edge sword in cancer and autoimmune disorders.
Topics: Adenine; Animals; Autoimmune Diseases; Humans; Immunologic Factors; Neoplasms; Piperidines; Protein- | 2016 |
3 trials available for adenine and Autoimmune Disease
| Article | Year |
|---|---|
Preexisting and treatment-emergent autoimmune cytopenias in patients with CLL treated with targeted drugs.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Autoimmune | 2021 |
Ibrutinib and idelalisib in the management of CLL-associated autoimmune cytopenias: a study from the FILO group.
Topics: Adenine; Autoimmune Diseases; Disease-Free Survival; Female; Hematologic Diseases; Humans; Leukemia, | 2019 |
Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib.
Topics: Adenine; Aged; Anemia; Autoimmune Diseases; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mi | 2016 |
12 other studies available for adenine and Autoimmune Disease
| Article | Year |
|---|---|
[Improvement of autoimmune cytopenia with ibrutinib in a chronic lymphocytic leukemia patient complicated by monoclonal immunoglobulin deposition disease].
Topics: Adenine; Aged; Antibodies, Monoclonal; Autoimmune Diseases; Female; Humans; Leukemia, Lymphocytic, C | 2019 |
Androgen receptor inhibition alleviated inflammation in experimental autoimmune myocarditis by increasing autophagy in macrophages.
Topics: Adenine; Androgen Receptor Antagonists; Animals; Anti-Inflammatory Agents; Apoptosis; Autoimmune Dis | 2021 |
Autoimmune myelitis in a CLL patient undergoing treatment with ibrutinib.
Topics: Adenine; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Aut | 2019 |
Autoimmune cytopenias in patients with chronic lymphocytic leukaemia treated with ibrutinib in routine clinical practice at an academic medical centre.
Topics: Academic Medical Centers; Adenine; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Disease-Free | 2018 |
Autophagy contributes to IL-17-induced plasma cell differentiation in experimental autoimmune myocarditis.
Topics: Adenine; ADP-ribosyl Cyclase 1; Animals; Apoptosis Regulatory Proteins; Autoimmune Diseases; Autopha | 2014 |
Clinical response to ibrutinib is accompanied by normalization of the T-cell environment in CLL-related autoimmune cytopenia.
Topics: Adenine; Aged; Autoimmune Diseases; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Age | 2016 |
Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7.
Topics: Adenine; Animals; Autoimmune Diseases; Encephalomyelitis, Autoimmune, Experimental; Immune Tolerance | 2009 |
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy.
Topics: Adenine; Administration, Oral; Agammaglobulinaemia Tyrosine Kinase; Animals; Arthritis, Experimental | 2010 |
Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system.
Topics: Adenine; Adenosylhomocysteinase; Animals; Autoimmune Diseases; Butyrates; Calcium; CD4-Positive T-Ly | 2007 |
Reactive oxygen species modified thymine and poly(dT) present unique epitope for human anti-DNA autoantibodies.
Topics: Adenine; Animals; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Cattle; Enzyme | 1997 |
Studies on the platelet defect in alcoholism.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Alcoholism; Autoimmune Diseases; Blood Plate | 1975 |
Repair of chemical carcinogen-induced damage in DNA of human lymphocytes and lymphoid cell lines--studies of the kinetics of removal of O6-methylguanine and 3-methyladenine.
Topics: Adenine; Autoimmune Diseases; Carcinogens; Cell Line; DNA Repair; Guanine; Humans; Kinetics; Lymphoc | 1986 |