adenine has been researched along with Astrocytoma in 13 studies
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In human D384 astrocytoma cells, cyclic AMP accumulation can be conveniently studied after labelling of the adenosine triphosphate pool (15 fmol cell-1) with [3H]adenine." | 7.68 | Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon. ( Altiok, N; Balmforth, AJ; Fredholm, BB, 1992) |
| "In human D384 astrocytoma cells, cyclic AMP accumulation can be conveniently studied after labelling of the adenosine triphosphate pool (15 fmol cell-1) with [3H]adenine." | 3.68 | Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon. ( Altiok, N; Balmforth, AJ; Fredholm, BB, 1992) |
| "The characteristics of the effects of catecholamines, prostaglandins, and adenosine on the adenosine 3',5'-monophosphate (cAMP) content of human astrocytoma cells are described." | 3.65 | Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells. ( Clark, RB; Cubeddu, L; Johnson, GL; Ortmann, R; Perkins, JP; Su, YF, 1975) |
| "4." | 1.29 | Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate. ( Boucher, RC; Harden, TK; Lazarowski, ER; Stutts, MJ; Watt, WC, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borrmann, T | 1 |
| Abdelrahman, A | 1 |
| Volpini, R | 1 |
| Lambertucci, C | 1 |
| Alksnis, E | 1 |
| Gorzalka, S | 1 |
| Knospe, M | 1 |
| Schiedel, AC | 1 |
| Cristalli, G | 1 |
| Müller, CE | 1 |
| McFarland, AJ | 1 |
| Anoopkumar-Dukie, S | 1 |
| Perkins, AV | 1 |
| Davey, AK | 1 |
| Grant, GD | 1 |
| Levitt, R | 1 |
| Buckner, JC | 1 |
| Cascino, TL | 1 |
| Burch, PA | 1 |
| Morton, RF | 1 |
| Westberg, MW | 1 |
| Goldberg, RM | 1 |
| Gallagher, JG | 1 |
| O'Fallon, JR | 1 |
| Scheithauer, BW | 1 |
| Lazarowski, ER | 1 |
| Watt, WC | 1 |
| Stutts, MJ | 1 |
| Boucher, RC | 1 |
| Harden, TK | 1 |
| Barankiewicz, J | 2 |
| Danks, AM | 2 |
| Abushanab, E | 1 |
| Makings, L | 1 |
| Wiemann, T | 1 |
| Wallis, RA | 1 |
| Pragnacharyulu, PV | 1 |
| Fox, A | 1 |
| Marangos, PJ | 2 |
| Clark, RB | 2 |
| Su, YF | 2 |
| Ortmann, R | 1 |
| Cubeddu, L | 1 |
| Johnson, GL | 1 |
| Perkins, JP | 2 |
| Lewin, E | 2 |
| Bleck, V | 1 |
| Altiok, N | 1 |
| Balmforth, AJ | 1 |
| Fredholm, BB | 1 |
| Morgan, AJ | 1 |
| Murray, KJ | 1 |
| Challiss, RA | 1 |
| Louis, DN | 1 |
| von Deimling, A | 1 |
| Seizinger, BR | 1 |
| Gross, R | 1 |
1 review available for adenine and Astrocytoma
| Article | Year |
|---|---|
Can adenosine deaminase inhibitors be cytoprotective agents?
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Astrocytoma; Enzyme Inhibitors; Humans; Kinetics; | 1998 |
1 trial available for adenine and Astrocytoma
| Article | Year |
|---|---|
Phase II study of amonafide in patients with recurrent glioma.
Topics: Adenine; Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; | 1995 |
11 other studies available for adenine and Astrocytoma
| Article | Year |
|---|---|
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.
Topics: Adenine; Animals; Astrocytoma; Cell Line; Cell Line, Tumor; Cerebral Cortex; Humans; Ligands; Protei | 2009 |
Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity.
Topics: Adenine; Antioxidants; Apoptosis; Astrocytes; Astrocytoma; Autophagy; Cell Line, Tumor; Cells, Cultu | 2012 |
Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate.
Topics: Adenine; Adenine Nucleotides; Astrocytoma; Cloning, Molecular; Dinucleoside Phosphates; Humans; Inos | 1995 |
Regulation of adenosine concentration and cytoprotective effects of novel reversible adenosine deaminase inhibitors.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Astrocytoma; Cattle; Cytoprotection; En | 1997 |
Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Astrocytoma; Catecholamines; Cells, Cultured; Cyclic AM | 1975 |
Uptake and release of adenosine by cultured astrocytoma cells.
Topics: Adenine; Adenosine; Astrocytoma; Biological Transport; Cell Line; Humans; Kinetics | 1979 |
Effects of phenytoin on the release of 14C-adenine derivatives.
Topics: Adenine; Animals; Astrocytoma; Brain Neoplasms; Carbamazepine; Cells, Cultured; Cerebral Cortex; Hyp | 1977 |
Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon.
Topics: Adenine; Adenine Nucleotides; Astrocytoma; Bradykinin; Cyclic AMP; Dipyridamole; Humans; In Vitro Te | 1992 |
Comparison of methods to assess cyclic AMP turnover under conditions of agonist stimulation in 1321N1 astrocytoma cells.
Topics: Adenine; Adenosine Triphosphate; Animals; Astrocytoma; Carbon Radioisotopes; Cell Line; Cyclic AMP; | 1992 |
A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens.
Topics: Adenine; Astrocytoma; Brain Neoplasms; Chromosome Deletion; Cytidine; DNA, Neoplasm; Glioma; Heteroz | 1992 |
Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Astrocyt | 1974 |