adenine has been researched along with Aortic Diseases in 12 studies
Aortic Diseases: Pathological processes involving any part of the AORTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combined nutrients supplementation with omega-3 FA and MK-7 may be helpful for aortic VC prevention, reducing osteoclast activation and improving sarcopenia-related molecules in adenine and low-protein diet induced uremic rats." | 4.12 | Omega-3 fatty acid and menaquinone-7 combination are helpful for aortic calcification prevention, reducing osteoclast area of bone and Fox0 expression of muscle in uremic rats. ( An, WS; Jeong, EG; Jeong, YI; Kim, SE; Lee, SM; Rha, SH, 2022) |
| " Uremia-related medial calcification was induced by feeding rats an adenine low-protein diet for 4 weeks." | 3.76 | Chondrocyte rather than osteoblast conversion of vascular cells underlies medial calcification in uremic rats. ( D'Haese, PC; Dauwe, S; De Broe, ME; De Schutter, T; Neven, E; Persy, V, 2010) |
| "After adenine dosing, significant hyperphosphatemia, hypocalcemia and secondary hyperparathyroidism (2HPT) were observed during the experimental period of 15 weeks." | 3.75 | Vascular calcification and secondary hyperparathyroidism of severe chronic kidney disease and its relation to serum phosphate and calcium levels. ( Fujimori, A; Fukushima, S; Itoh, H; Mizukami, K; Nara, H; Okada, M; Sanagi, M; Takakura, K; Terai, K, 2009) |
| "Vascular calcification is a common finding in atherosclerosis and in patients with chronic kidney disease." | 1.51 | AT2 receptor stimulation inhibits phosphate-induced vascular calcification. ( Bai, HY; Higaki, A; Higaki, J; Horiuchi, M; Iwanami, J; Kan-No, H; Kukida, M; Min, LJ; Mogi, M; Okura, T; Shan, BS; Tsukuda, K; Yamauchi, T, 2019) |
| "Vascular calcification is highly correlated with increased cardiovascular morbidity and mortality." | 1.40 | Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro. ( Feng, H; Lei, H; Li, H; Li, L; Wang, C; Wang, JY; Wu, D; Wu, LL; Zhou, Y, 2014) |
| "After 1 week, rats with chronic renal failure were treated with vehicle, 375 or 750 mg/kg CaMg, or 750 mg/kg sevelamer by daily gavage for 5 weeks." | 1.39 | Effect of a magnesium-based phosphate binder on medial calcification in a rat model of uremia. ( Behets, GJ; D'Haese, PC; De Schutter, TM; Geryl, H; Gundlach, K; Neven, E; Passlick-Deetjen, J; Peter, ME; Steppan, S, 2013) |
| "Adenine-treated rats showed marked elevations of serum phosphorus, PTH and FGF23 levels associated with parathyroid hyperplasia and aortic calcification." | 1.33 | [Effects of intermittent treatment with sevelamer hydrochloride on parathyroid hyperplasia and vascular calcification in rats with chronic kidney disease]. ( Abe, M; Kobayashi, N; Miyata, S; Nagano, N; Wada, M; Wakita, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SM | 1 |
| Jeong, EG | 1 |
| Jeong, YI | 1 |
| Rha, SH | 1 |
| Kim, SE | 1 |
| An, WS | 1 |
| Yao, Z | 1 |
| Xu, Y | 1 |
| Ma, W | 1 |
| Sun, XY | 1 |
| Jia, S | 1 |
| Zheng, Y | 1 |
| Liu, X | 1 |
| Fan, Y | 1 |
| Wang, C | 2 |
| Kukida, M | 1 |
| Mogi, M | 1 |
| Kan-No, H | 1 |
| Tsukuda, K | 1 |
| Bai, HY | 1 |
| Shan, BS | 1 |
| Yamauchi, T | 1 |
| Higaki, A | 1 |
| Min, LJ | 1 |
| Iwanami, J | 1 |
| Okura, T | 1 |
| Higaki, J | 1 |
| Horiuchi, M | 1 |
| De Schutter, TM | 1 |
| Behets, GJ | 1 |
| Geryl, H | 1 |
| Peter, ME | 1 |
| Steppan, S | 1 |
| Gundlach, K | 1 |
| Passlick-Deetjen, J | 1 |
| D'Haese, PC | 3 |
| Neven, E | 3 |
| Zhou, Y | 1 |
| Wang, JY | 1 |
| Feng, H | 1 |
| Li, L | 1 |
| Wu, D | 1 |
| Lei, H | 1 |
| Li, H | 1 |
| Wu, LL | 1 |
| Tatsumoto, N | 1 |
| Yamada, S | 1 |
| Tokumoto, M | 1 |
| Eriguchi, M | 1 |
| Noguchi, H | 1 |
| Torisu, K | 1 |
| Tsuruya, K | 1 |
| Kitazono, T | 1 |
| Gao, C | 1 |
| Fu, Y | 1 |
| Li, Y | 1 |
| Zhang, X | 1 |
| Zhang, L | 1 |
| Yu, F | 1 |
| Xu, SS | 1 |
| Xu, Q | 1 |
| Zhu, Y | 1 |
| Guan, Y | 1 |
| Wang, X | 1 |
| Kong, W | 1 |
| Terai, K | 1 |
| Nara, H | 1 |
| Takakura, K | 1 |
| Mizukami, K | 1 |
| Sanagi, M | 1 |
| Fukushima, S | 1 |
| Fujimori, A | 1 |
| Itoh, H | 1 |
| Okada, M | 1 |
| Postnov, AA | 1 |
| De Clerck, NM | 1 |
| Persy, VP | 1 |
| Persy, V | 1 |
| Dauwe, S | 1 |
| De Schutter, T | 1 |
| De Broe, ME | 1 |
| Nagano, N | 1 |
| Miyata, S | 1 |
| Abe, M | 1 |
| Wakita, S | 1 |
| Kobayashi, N | 1 |
| Wada, M | 1 |
| Tamagaki, K | 1 |
| Yuan, Q | 1 |
| Ohkawa, H | 1 |
| Imazeki, I | 1 |
| Moriguchi, Y | 1 |
| Imai, N | 1 |
| Sasaki, S | 1 |
| Takeda, K | 1 |
| Fukagawa, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Spironolactone on the Progression of Coronary Calcification in Peritoneal Dialysis Patients[NCT03314493] | Phase 3 | 33 participants (Actual) | Interventional | 2014-11-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for adenine and Aortic Diseases
| Article | Year |
|---|---|
Omega-3 fatty acid and menaquinone-7 combination are helpful for aortic calcification prevention, reducing osteoclast area of bone and Fox0 expression of muscle in uremic rats.
Topics: Adenine; Animals; Aortic Diseases; Bone Diseases, Metabolic; Drug Therapy, Combination; Fatty Acids, | 2022 |
Magnesium Citrate Protects Against Vascular Calcification in an Adenine-induced Chronic Renal Failure Rat Model.
Topics: Actins; Adenine; Alkaline Phosphatase; Animals; Aorta; Aortic Diseases; Calcium; Cardiovascular Agen | 2018 |
AT2 receptor stimulation inhibits phosphate-induced vascular calcification.
Topics: Adenine; Animals; Aorta, Thoracic; Aortic Diseases; Cells, Cultured; Disease Models, Animal; Humans; | 2019 |
Effect of a magnesium-based phosphate binder on medial calcification in a rat model of uremia.
Topics: Acetates; Adenine; Animals; Aortic Diseases; Bone Morphogenetic Protein 2; Calcium; Calcium Compound | 2013 |
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Topics: Actins; Adenine; Alkaline Phosphatase; Animals; Aorta, Abdominal; Aortic Diseases; Bone Morphogeneti | 2014 |
Spironolactone ameliorates arterial medial calcification in uremic rats: the role of mineralocorticoid receptor signaling in vascular calcification.
Topics: Adenine; Animals; Aorta, Abdominal; Aortic Diseases; Apoptosis; Biomarkers; Disease Models, Animal; | 2015 |
Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification.
Topics: Adenine; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Calcitriol; Cells, Cultured; C | 2016 |
Vascular calcification and secondary hyperparathyroidism of severe chronic kidney disease and its relation to serum phosphate and calcium levels.
Topics: Adenine; Animals; Aortic Diseases; Biomarkers; Blood Urea Nitrogen; Calcinosis; Calcium; Calcium Car | 2009 |
Possibilities and limits of X-ray microtomography for in vivo and ex vivo detection of vascular calcifications.
Topics: Adenine; Animals; Aorta; Aortic Diseases; Aortography; Calcinosis; Calcium; Disease Models, Animal; | 2009 |
Chondrocyte rather than osteoblast conversion of vascular cells underlies medial calcification in uremic rats.
Topics: Adenine; Animals; Aortic Diseases; Biomarkers; Calcinosis; Calcium; Cell Transdifferentiation; Chond | 2010 |
[Effects of intermittent treatment with sevelamer hydrochloride on parathyroid hyperplasia and vascular calcification in rats with chronic kidney disease].
Topics: Adenine; Animals; Aortic Diseases; Calcinosis; Calcium; Disease Models, Animal; Drug Administration | 2005 |
Severe hyperparathyroidism with bone abnormalities and metastatic calcification in rats with adenine-induced uraemia.
Topics: Adenine; Animals; Aortic Diseases; Blood Urea Nitrogen; Calcinosis; Calcitriol; Calcium; Chronic Kid | 2006 |