adenine has been researched along with Aging in 71 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Excerpt | Relevance | Reference |
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" For illustration, a pharmacodynamic model for leukopenia was constructed by stepwise linear regression from data of 41 patients with cancer treated with the drug amonafide." | 5.07 | Bootstrap validation of pharmacodynamic models defined via stepwise linear regression. ( Mick, R; Ratain, MJ, 1994) |
" Previous studies have suggested a link between gene-specific reductions in adenosine to inosine RNA editing and aging in the human brain." | 3.79 | A-to-I RNA editing does not change with age in the healthy male rat brain. ( de Magalhães, JP; Holmes, AP; Merry, BJ; Wood, SH, 2013) |
"Erythrocytes of patients with polycythemia vera exhibited increased activity of oxidative pentose shunt, accelerated generation of phosphoribosylpyrophosphate, increased incorporation of 14C-adenine into nucleotides, and increased activity and thermostability of adenine-phosphoribosyltransferase." | 3.65 | Pentose shunt, phosphoribosylpyrophosphate generation and purine-phosphoribosyltransferases in erythrocytes of patients with polycythemia vera. ( Boer, P; Brosh, S; de Vries, A; Elazar, E; Pinkhas, J; Sperling, O; Szeinberg, A, 1975) |
"Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear." | 1.46 | Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states. ( Blanco, P; Bolen, CR; Chang, J; Daburon, S; Davis, MM; Déchanet-Merville, J; Dekker, CL; Douchet, I; Faustin, B; Fragiadakis, GK; Furman, D; Ganio, EA; Gaudilliere, B; Haddad, F; Jojic, V; Kuo, CJ; Lartigue, L; Moreau, JF; Nolan, GP; Spitzer, MH, 2017) |
" We investigated whether tenofovir plus didanosine at a weight-adjusted dosage could be responsible for such an effect, and factors associated with CD4 + T cell count evolution under this combination." | 1.34 | CD4+ T cell evolution and predictors of its trend before and after tenofovir/didanosine backbone in the presence of sustained undetectable HIV plasma viral load. ( Antinori, A; Antonucci, F; Barreiro, P; Carosi, G; De Silvestri, A; El Hamad, I; Ladisa, N; Lapadula, G; Maggiolo, F; Mandalia, S; Maserati, R; Migliorino, G; Pierotti, P; Sighinolfi, L; Soriano, V; Suter, F; Torti, C, 2007) |
"Obesity was accompanied by insulin resistance, and 65% reduction (P<0." | 1.34 | Age related obesity-induced shortening of GLUT4 mRNA poly(A) tail length in rat gastrocnemius skeletal muscle. ( Giannocco, G; Machado, UF; Nunes, MT; Seraphim, PM, 2007) |
"Adenosine is an ubiquitously occurring endogenous nucleoside that via cell surface receptors exerts multiple antihypertensive actions, and mediates a number of biological responses that may reduce cardiovascular disease risk." | 1.30 | Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats. ( Jackson, EK; Kusaka, H; Li, P; Tofovic, SP, 1998) |
"Adenosine binding was inhibited by only 30% under similar conditions." | 1.26 | Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues. ( Corbin, JD; Sugden, PH, 1976) |
"The adenine action has been proved down to a concentration of 3 X 10(-6) M." | 1.25 | [Regulation of age-dependent phenomena. Influence of C6-substituted purines on cell aggregation and cell migration in primary cultures of lense epithelial cells]. ( Glässer, D; Iwig, M; Weber, E, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (35.21) | 18.7374 |
1990's | 9 (12.68) | 18.2507 |
2000's | 15 (21.13) | 29.6817 |
2010's | 15 (21.13) | 24.3611 |
2020's | 7 (9.86) | 2.80 |
Authors | Studies |
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Huang, J | 3 |
Yu, W | 1 |
He, Q | 1 |
He, X | 1 |
Yang, M | 3 |
Chen, W | 2 |
Han, W | 1 |
Tölle, M | 1 |
Henkel, C | 1 |
Herrmann, J | 1 |
Daniel, C | 1 |
Babic, M | 1 |
Xia, M | 1 |
Schulz, AM | 1 |
Amann, K | 1 |
van der Giet, M | 1 |
Schuchardt, M | 1 |
Chen, Y | 1 |
Wang, Q | 3 |
Luo, H | 1 |
Deng, S | 1 |
Tian, Y | 1 |
Wang, S | 1 |
Walmsley, S | 2 |
Clarke, R | 2 |
Lee, T | 2 |
Singer, J | 2 |
Cheung, AM | 2 |
Smaill, F | 2 |
De Pokomandy, A | 2 |
Trottier, S | 2 |
Messina, E | 2 |
Guaraldi, G | 2 |
Wang, M | 1 |
Wang, XF | 1 |
Li, YM | 1 |
Chen, N | 1 |
Fan, Y | 3 |
Huang, WK | 1 |
Hu, SF | 1 |
Rao, M | 1 |
Zhang, YZ | 1 |
Su, P | 1 |
Halim, AA | 1 |
Alsayed, B | 1 |
Embarak, S | 1 |
Yaseen, T | 1 |
Dabbous, S | 1 |
Fontaine, O | 1 |
Dueluzeau, R | 1 |
Raibaud, P | 1 |
Chabanet, C | 1 |
Popoff, MR | 1 |
Badoual, J | 1 |
Gabilan, JC | 1 |
Andremont, A | 1 |
Gómez, L | 1 |
Andrés, S | 1 |
Sánchez, J | 1 |
Alonso, JM | 1 |
Rey, J | 1 |
López, F | 1 |
Jiménez, A | 1 |
Yan, Z | 1 |
Zhou, L | 1 |
Zhao, Y | 3 |
Wang, J | 7 |
Huang, L | 2 |
Hu, K | 1 |
Liu, H | 4 |
Wang, H | 3 |
Guo, Z | 1 |
Song, Y | 1 |
Huang, H | 4 |
Yang, R | 1 |
Owen, TW | 1 |
Al-Kaysi, RO | 1 |
Bardeen, CJ | 1 |
Cheng, Q | 1 |
Wu, S | 1 |
Cheng, T | 1 |
Zhou, X | 1 |
Wang, B | 4 |
Zhang, Q | 4 |
Wu, X | 2 |
Yao, Y | 3 |
Ochiai, T | 1 |
Ishiguro, H | 2 |
Nakano, R | 2 |
Kubota, Y | 2 |
Hara, M | 1 |
Sunada, K | 1 |
Hashimoto, K | 1 |
Kajioka, J | 1 |
Fujishima, A | 1 |
Jiao, J | 3 |
Gai, QY | 3 |
Wang, W | 2 |
Zang, YP | 2 |
Niu, LL | 2 |
Fu, YJ | 3 |
Wang, X | 4 |
Yao, LP | 1 |
Qin, QP | 1 |
Wang, ZY | 1 |
Liu, J | 4 |
Aleksic Sabo, V | 1 |
Knezevic, P | 1 |
Borges-Argáez, R | 1 |
Chan-Balan, R | 1 |
Cetina-Montejo, L | 1 |
Ayora-Talavera, G | 1 |
Sansores-Peraza, P | 1 |
Gómez-Carballo, J | 1 |
Cáceres-Farfán, M | 1 |
Jang, J | 1 |
Akin, D | 1 |
Bashir, R | 1 |
Yu, Z | 1 |
Zhu, J | 2 |
Jiang, H | 1 |
He, C | 2 |
Xiao, Z | 1 |
Xu, J | 2 |
Sun, Q | 1 |
Han, D | 1 |
Lei, H | 1 |
Zhao, K | 2 |
Zhu, L | 1 |
Li, X | 4 |
Fu, H | 2 |
Wilson, BK | 1 |
Step, DL | 1 |
Maxwell, CL | 1 |
Gifford, CA | 1 |
Richards, CJ | 1 |
Krehbiel, CR | 1 |
Warner, JM | 1 |
Doerr, AJ | 1 |
Erickson, GE | 1 |
Guretzky, JA | 1 |
Rasby, RJ | 1 |
Watson, AK | 1 |
Klopfenstein, TJ | 1 |
Sun, Y | 4 |
Liu, Z | 3 |
Pham, TD | 1 |
Lee, BK | 1 |
Yang, FC | 1 |
Wu, KH | 1 |
Lin, WP | 1 |
Hu, MK | 1 |
Lin, L | 3 |
Shao, J | 1 |
Sun, M | 1 |
Xu, G | 1 |
Zhang, X | 6 |
Xu, N | 1 |
Wang, R | 1 |
Liu, S | 1 |
He, H | 1 |
Dong, X | 2 |
Yang, Q | 1 |
Duan, S | 1 |
Yu, Y | 2 |
Han, J | 2 |
Zhang, C | 5 |
Chen, L | 2 |
Yang, X | 1 |
Li, W | 3 |
Wang, T | 2 |
Campbell, DA | 1 |
Gao, K | 1 |
Zager, RA | 1 |
Johnson, ACM | 1 |
Guillem, A | 1 |
Keyser, J | 1 |
Singh, B | 1 |
Steubl, D | 1 |
Schneider, MP | 1 |
Meiselbach, H | 1 |
Nadal, J | 1 |
Schmid, MC | 1 |
Saritas, T | 1 |
Krane, V | 1 |
Sommerer, C | 1 |
Baid-Agrawal, S | 1 |
Voelkl, J | 1 |
Kotsis, F | 1 |
Köttgen, A | 1 |
Eckardt, KU | 1 |
Scherberich, JE | 1 |
Li, H | 4 |
Yao, L | 2 |
Sun, L | 3 |
Zhu, Z | 1 |
Naren, N | 1 |
Zhang, XX | 2 |
Gentile, GL | 1 |
Rupert, AS | 1 |
Carrasco, LI | 1 |
Garcia, EM | 1 |
Kumar, NG | 1 |
Walsh, SW | 1 |
Jefferson, KK | 1 |
Guest, RL | 1 |
Samé Guerra, D | 1 |
Wissler, M | 1 |
Grimm, J | 1 |
Silhavy, TJ | 1 |
Lee, JH | 2 |
Yoo, JS | 1 |
Kim, Y | 1 |
Kim, JS | 2 |
Lee, EJ | 1 |
Roe, JH | 1 |
Delorme, M | 1 |
Bouchard, PA | 1 |
Simon, M | 1 |
Simard, S | 1 |
Lellouche, F | 1 |
D'Urzo, KA | 1 |
Mok, F | 1 |
D'Urzo, AD | 1 |
Koneru, B | 1 |
Lopez, G | 1 |
Farooqi, A | 1 |
Conkrite, KL | 1 |
Nguyen, TH | 1 |
Macha, SJ | 1 |
Modi, A | 1 |
Rokita, JL | 1 |
Urias, E | 1 |
Hindle, A | 1 |
Davidson, H | 1 |
Mccoy, K | 1 |
Nance, J | 1 |
Yazdani, V | 1 |
Irwin, MS | 1 |
Yang, S | 2 |
Wheeler, DA | 1 |
Maris, JM | 1 |
Diskin, SJ | 1 |
Reynolds, CP | 1 |
Abhilash, L | 1 |
Kalliyil, A | 1 |
Sheeba, V | 1 |
Hartley, AM | 2 |
Meunier, B | 2 |
Pinotsis, N | 1 |
Maréchal, A | 2 |
Xu, JY | 1 |
Genko, N | 1 |
Haraux, F | 1 |
Rich, PR | 1 |
Kamalanathan, M | 1 |
Doyle, SM | 1 |
Xu, C | 1 |
Achberger, AM | 1 |
Wade, TL | 1 |
Schwehr, K | 1 |
Santschi, PH | 1 |
Sylvan, JB | 1 |
Quigg, A | 1 |
Leong, W | 1 |
Xu, W | 2 |
Gao, S | 1 |
Zhai, X | 1 |
Wang, C | 2 |
Gilson, E | 1 |
Ye, J | 1 |
Lu, Y | 1 |
Yan, R | 1 |
Zhang, Y | 6 |
Hu, Z | 1 |
You, Q | 1 |
Cai, Q | 1 |
Yang, D | 1 |
Gu, S | 1 |
Dai, H | 1 |
Zhao, X | 1 |
Gui, C | 1 |
Gui, J | 1 |
Wu, PK | 1 |
Hong, SK | 1 |
Starenki, D | 1 |
Oshima, K | 1 |
Shao, H | 1 |
Gestwicki, JE | 1 |
Tsai, S | 1 |
Park, JI | 1 |
Wang, Y | 7 |
Zhao, R | 1 |
Gu, Z | 1 |
Dong, C | 2 |
Guo, G | 1 |
Li, L | 4 |
Barrett, HE | 1 |
Meester, EJ | 1 |
van Gaalen, K | 1 |
van der Heiden, K | 1 |
Krenning, BJ | 1 |
Beekman, FJ | 1 |
de Blois, E | 1 |
de Swart, J | 1 |
Verhagen, HJ | 1 |
Maina, T | 1 |
Nock, BA | 1 |
Norenberg, JP | 1 |
de Jong, M | 1 |
Gijsen, FJH | 1 |
Bernsen, MR | 1 |
Martínez-Milla, J | 1 |
Galán-Arriola, C | 1 |
Carnero, M | 1 |
Cobiella, J | 1 |
Pérez-Camargo, D | 1 |
Bautista-Hernández, V | 1 |
Rigol, M | 1 |
Solanes, N | 1 |
Villena-Gutierrez, R | 1 |
Lobo, M | 1 |
Mateo, J | 1 |
Vilchez-Tschischke, JP | 1 |
Salinas, B | 1 |
Cussó, L | 1 |
López, GJ | 1 |
Fuster, V | 1 |
Desco, M | 1 |
Sanchez-González, J | 1 |
Ibanez, B | 1 |
van den Berg, P | 1 |
Schweitzer, DH | 1 |
van Haard, PMM | 1 |
Geusens, PP | 1 |
van den Bergh, JP | 1 |
Zhu, X | 2 |
Huang, X | 2 |
Xu, H | 2 |
Yang, G | 2 |
Lin, Z | 1 |
Salem, HF | 1 |
Nafady, MM | 1 |
Kharshoum, RM | 1 |
Abd El-Ghafar, OA | 1 |
Farouk, HO | 1 |
Domiciano, D | 1 |
Nery, FC | 1 |
de Carvalho, PA | 1 |
Prudente, DO | 1 |
de Souza, LB | 1 |
Chalfun-Júnior, A | 1 |
Paiva, R | 1 |
Marchiori, PER | 1 |
Lu, M | 2 |
An, Z | 1 |
Jiang, J | 2 |
Li, J | 7 |
Du, S | 1 |
Zhou, H | 1 |
Cui, J | 1 |
Wu, W | 1 |
Liu, Y | 7 |
Song, J | 1 |
Lian, Q | 1 |
Uddin Ahmad, Z | 1 |
Gang, DD | 1 |
Konggidinata, MI | 1 |
Gallo, AA | 1 |
Zappi, ME | 1 |
Yang, TWW | 1 |
Johari, Y | 1 |
Burton, PR | 1 |
Earnest, A | 1 |
Shaw, K | 1 |
Hare, JL | 1 |
Brown, WA | 1 |
Kim, GA | 1 |
Han, S | 1 |
Choi, GH | 1 |
Choi, J | 1 |
Lim, YS | 1 |
Gallo, A | 1 |
Cancelli, C | 1 |
Ceron, E | 1 |
Covino, M | 1 |
Capoluongo, E | 1 |
Pocino, K | 1 |
Ianiro, G | 1 |
Cammarota, G | 1 |
Gasbarrini, A | 1 |
Montalto, M | 1 |
Somasundar, Y | 1 |
Lu, IC | 1 |
Mills, MR | 1 |
Qian, LY | 1 |
Olivares, X | 1 |
Ryabov, AD | 1 |
Collins, TJ | 1 |
Zhao, L | 1 |
Doddipatla, S | 1 |
Thomas, AM | 1 |
Nikolayev, AA | 1 |
Galimova, GR | 1 |
Azyazov, VN | 1 |
Mebel, AM | 1 |
Kaiser, RI | 1 |
Guo, S | 1 |
Yang, P | 1 |
Yu, X | 2 |
Wu, Y | 2 |
Zhang, H | 1 |
Yu, B | 2 |
Han, B | 1 |
George, MW | 1 |
Moor, MB | 1 |
Bonny, O | 1 |
Langenberg, E | 1 |
Paik, H | 1 |
Smith, EH | 1 |
Nair, HP | 1 |
Hanke, I | 1 |
Ganschow, S | 1 |
Catalan, G | 1 |
Domingo, N | 1 |
Schlom, DG | 1 |
Assefa, MK | 1 |
Wu, G | 2 |
Hayton, TW | 1 |
Becker, B | 1 |
Enikeev, D | 1 |
Netsch, C | 1 |
Gross, AJ | 1 |
Laukhtina, E | 1 |
Glybochko, P | 1 |
Rapoport, L | 1 |
Herrmann, TRW | 1 |
Taratkin, M | 1 |
Dai, W | 1 |
Shi, J | 2 |
Carreno, J | 1 |
Kloner, RA | 1 |
Pickersgill, NA | 1 |
Vetter, JM | 1 |
Kim, EH | 1 |
Cope, SJ | 1 |
Du, K | 1 |
Venkatesh, R | 1 |
Giardina, JD | 1 |
Saad, NES | 1 |
Bhayani, SB | 1 |
Figenshau, RS | 1 |
Eriksson, J | 1 |
Landfeldt, E | 1 |
Ireland, S | 1 |
Jackson, C | 1 |
Wyatt, E | 1 |
Gaudig, M | 1 |
Stancill, JS | 1 |
Happ, JT | 1 |
Broniowska, KA | 1 |
Hogg, N | 1 |
Corbett, JA | 1 |
Tang, LF | 1 |
Bi, YL | 1 |
Sun, YB | 1 |
Wang, AL | 1 |
Xiao, BH | 1 |
Wang, LF | 1 |
Qiu, SW | 1 |
Guo, SW | 1 |
Wáng, YXJ | 1 |
Sun, J | 2 |
Chu, S | 1 |
Pan, Q | 1 |
Li, D | 2 |
Zheng, S | 2 |
Ma, L | 1 |
Wang, L | 4 |
Hu, T | 1 |
Wang, F | 1 |
Han, Z | 1 |
Yin, Z | 1 |
Ge, X | 1 |
Xie, K | 1 |
Lei, P | 1 |
Dias-Santagata, D | 1 |
Lennerz, JK | 1 |
Sadow, PM | 1 |
Frazier, RP | 1 |
Govinda Raju, S | 1 |
Henry, D | 1 |
Chung, T | 1 |
Kherani, J | 1 |
Rothenberg, SM | 1 |
Wirth, LJ | 1 |
Marti, CN | 1 |
Choi, NG | 1 |
Bae, SJ | 1 |
Ni, L | 1 |
Luo, X | 1 |
Dai, T | 1 |
Yang, Y | 3 |
Lee, R | 1 |
Fleischer, AS | 1 |
Wemhoff, AP | 1 |
Ford, CR | 1 |
Kleppinger, EL | 1 |
Helms, K | 1 |
Bush, AA | 1 |
Luna-Abanto, J | 1 |
García Ruiz, L | 1 |
Laura Martinez, J | 1 |
Álvarez Larraondo, M | 1 |
Villoslada Terrones, V | 1 |
Dukic, L | 1 |
Maric, N | 1 |
Simundic, AM | 1 |
Chogtu, B | 1 |
Ommurugan, B | 1 |
Thomson, SR | 1 |
Kalthur, SG | 1 |
Benidir, M | 1 |
El Massoudi, S | 1 |
El Ghadraoui, L | 1 |
Lazraq, A | 1 |
Benjelloun, M | 1 |
Errachidi, F | 1 |
Cassar, M | 1 |
Law, AD | 1 |
Chow, ES | 1 |
Giebultowicz, JM | 1 |
Kretzschmar, D | 1 |
Salonurmi, T | 1 |
Nabil, H | 1 |
Ronkainen, J | 1 |
Hyötyläinen, T | 1 |
Hautajärvi, H | 1 |
Savolainen, MJ | 1 |
Tolonen, A | 1 |
Orešič, M | 1 |
Känsäkoski, P | 1 |
Rysä, J | 1 |
Hakkola, J | 1 |
Hukkanen, J | 1 |
Zhu, N | 1 |
Li, Y | 4 |
Du, Q | 1 |
Hao, P | 1 |
Cao, X | 1 |
Li, CX | 1 |
Zhao, S | 1 |
Luo, XM | 1 |
Feng, JX | 1 |
Gonzalez-Cotto, M | 1 |
Guo, L | 1 |
Karwan, M | 1 |
Sen, SK | 1 |
Barb, J | 1 |
Collado, CJ | 1 |
Elloumi, F | 1 |
Palmieri, EM | 1 |
Boelte, K | 1 |
Kolodgie, FD | 1 |
Finn, AV | 1 |
Biesecker, LG | 1 |
McVicar, DW | 1 |
Qu, F | 1 |
Deng, Z | 1 |
Xie, Y | 2 |
Tang, J | 3 |
Chen, Z | 2 |
Luo, W | 1 |
Xiong, D | 1 |
Zhao, D | 1 |
Fang, J | 1 |
Zhou, Z | 1 |
Niu, PP | 1 |
Song, B | 1 |
Xu, YM | 1 |
Zhang, Z | 2 |
Qiu, N | 1 |
Yin, J | 1 |
Zhang, J | 3 |
Guo, W | 1 |
Liu, M | 2 |
Liu, T | 2 |
Chen, D | 5 |
Luo, K | 1 |
He, Z | 2 |
Zheng, G | 1 |
Xu, F | 1 |
Sun, W | 1 |
Yin, F | 1 |
van Hest, JCM | 1 |
Du, L | 2 |
Shi, X | 1 |
Kang, S | 1 |
Duan, W | 1 |
Zhang, S | 2 |
Feng, J | 2 |
Qi, N | 1 |
Shen, G | 1 |
Ren, H | 1 |
Shang, Q | 1 |
Zhao, W | 2 |
Yang, Z | 2 |
Jiang, X | 3 |
Alame, M | 1 |
Cornillot, E | 1 |
Cacheux, V | 1 |
Tosato, G | 1 |
Four, M | 1 |
De Oliveira, L | 1 |
Gofflot, S | 1 |
Delvenne, P | 1 |
Turtoi, E | 1 |
Cabello-Aguilar, S | 1 |
Nishiyama, M | 1 |
Turtoi, A | 1 |
Costes-Martineau, V | 1 |
Colinge, J | 1 |
Guo, Q | 1 |
Quan, M | 1 |
Dong, J | 1 |
Bai, J | 1 |
Han, R | 1 |
Cai, Y | 1 |
Lv, YQ | 1 |
Chen, Q | 1 |
Lyu, HD | 1 |
Deng, L | 1 |
Zhou, D | 1 |
Xiao, X | 1 |
De Langhe, S | 1 |
Billadeau, DD | 1 |
Lou, Z | 1 |
Zhang, JS | 1 |
Xue, Z | 1 |
Shen, XD | 1 |
Gao, F | 1 |
Busuttil, RW | 1 |
Kupiec-Weglinski, JW | 1 |
Ji, H | 1 |
Otano, I | 1 |
Alvarez, M | 1 |
Minute, L | 1 |
Ochoa, MC | 1 |
Migueliz, I | 1 |
Molina, C | 1 |
Azpilikueta, A | 1 |
de Andrea, CE | 1 |
Etxeberria, I | 1 |
Sanmamed, MF | 1 |
Teijeira, Á | 1 |
Berraondo, P | 1 |
Melero, I | 1 |
Zhong, Z | 1 |
Xie, X | 1 |
Yu, Q | 1 |
Zhou, C | 1 |
Liu, C | 2 |
Liu, W | 1 |
Yin, Y | 1 |
Li, CW | 1 |
Hsu, JL | 1 |
Zhou, Q | 1 |
Hu, B | 1 |
Fu, P | 1 |
Atyah, M | 1 |
Ma, Q | 2 |
Xu, Y | 1 |
Dong, Q | 1 |
Hung, MC | 1 |
Ren, N | 1 |
Huang, P | 1 |
Liao, R | 1 |
Chen, X | 3 |
Cao, Q | 1 |
Yuan, X | 1 |
Nie, W | 1 |
Yang, J | 2 |
Shao, B | 1 |
Ma, X | 1 |
Bi, Z | 1 |
Liang, X | 1 |
Tie, Y | 1 |
Mo, F | 1 |
Xie, D | 1 |
Wei, Y | 1 |
Wei, X | 2 |
Dokla, EME | 1 |
Fang, CS | 1 |
Chu, PC | 1 |
Chang, CS | 1 |
Abouzid, KAM | 1 |
Chen, CS | 1 |
Blaszczyk, R | 1 |
Brzezinska, J | 1 |
Dymek, B | 1 |
Stanczak, PS | 1 |
Mazurkiewicz, M | 1 |
Olczak, J | 1 |
Nowicka, J | 1 |
Dzwonek, K | 1 |
Zagozdzon, A | 1 |
Golab, J | 1 |
Golebiowski, A | 1 |
Xin, Z | 1 |
Himmelbauer, MK | 1 |
Jones, JH | 1 |
Enyedy, I | 1 |
Gilfillan, R | 1 |
Hesson, T | 1 |
King, K | 1 |
Marcotte, DJ | 1 |
Murugan, P | 1 |
Santoro, JC | 1 |
Gonzalez-Lopez de Turiso, F | 1 |
Pedron, J | 1 |
Boudot, C | 1 |
Brossas, JY | 1 |
Pinault, E | 1 |
Bourgeade-Delmas, S | 1 |
Sournia-Saquet, A | 1 |
Boutet-Robinet, E | 1 |
Destere, A | 1 |
Tronnet, A | 1 |
Bergé, J | 1 |
Bonduelle, C | 1 |
Deraeve, C | 1 |
Pratviel, G | 1 |
Stigliani, JL | 1 |
Paris, L | 1 |
Mazier, D | 1 |
Corvaisier, S | 1 |
Since, M | 1 |
Malzert-Fréon, A | 1 |
Wyllie, S | 1 |
Milne, R | 1 |
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Serra, I | 1 |
Vanella, A | 1 |
Avitabile, M | 1 |
Barcellona, ML | 1 |
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Giuffrida, AM | 1 |
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Cornford, EM | 2 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Residual Immune Activation in HIV-infected Patients on Successful cART: Association Between Inflammasome Activation in Monocytes by Circulating Metabolites and Non AIDS Defining Comorbidities[NCT03191175] | 55 participants (Actual) | Observational | 2017-07-03 | Completed | |||
Immune Senescence in the Elderly: Comparison of Immune Responses to Influenza Vaccine In Adults of Different Ages[NCT01827462] | Phase 4 | 136 participants (Actual) | Interventional | 2007-10-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT01827462)
Timeframe: Day 0 annually while on study
Intervention | Participants (Count of Participants) |
---|---|
18-30 Years Old at Enrollment | 59 |
60-79 Years Old at Enrollment | 37 |
80-100 Years Old at Enrollment | 40 |
4 reviews available for adenine and Aging
Article | Year |
---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Endoplasmic reticulum proteostasis impairment in aging.
Topics: Adenine; Aging; Animals; Brain; Caenorhabditis elegans; Drosophila melanogaster; Endoplasmic Reticul | 2017 |
Base excision repair in nuclear and mitochondrial DNA.
Topics: Adenine; Aging; Animals; Base Sequence; Cell Line; Cell Nucleus; Cell-Free System; DNA; DNA Damage; | 2001 |
Maturation-inducing substance in starfishes.
Topics: Adenine; Aging; Chemical Phenomena; Chemistry; Drug Stability; Female; Fertility; Germ Cells; Gonads | 1973 |
3 trials available for adenine and Aging
Article | Year |
---|---|
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged | 2023 |
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged | 2023 |
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged | 2023 |
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Bootstrap validation of pharmacodynamic models defined via stepwise linear regression.
Topics: Acetylation; Adenine; Aging; Female; Humans; Imides; Isoquinolines; Leukocyte Count; Leukopenia; Mal | 1994 |
65 other studies available for adenine and Aging
Article | Year |
---|---|
Autophagy facilitates age-related cell apoptosis-a new insight from senile cataract.
Topics: Adenine; Adult; Aged; Aging; Apoptosis; Autophagy; Cataract; Cell Survival; Cells, Cultured; Cellula | 2022 |
Uremic mouse model to study vascular calcification and "inflamm-aging".
Topics: Adenine; Aging; Animals; Disease Models, Animal; Inflammation; Kidney Failure, Chronic; Mice; Rats; | 2022 |
Mechanisms of the ethanol extract of
Topics: Adenine; Aging; Amino Acids; Animals; Antioxidants; Catalase; Cholic Acid; Drosophila; Ethanol; Free | 2022 |
Cross-talk between autophagy and apoptosis regulates testicular injury/recovery induced by cadmium via PI3K with mTOR-independent pathway.
Topics: Adenine; Aging; Animals; Apoptosis; Autophagy; Cadmium; Cell Line; Male; Models, Biological; Oxidati | 2020 |
Renal Aging Resembles a Continuum Between Normal and Diseased Kidneys That Potentiates Inflammatory Response to Injury.
Topics: Adenine; Aging; Animals; Cytokines; Disease Models, Animal; Inflammation; Kidney Diseases; Male; Mic | 2021 |
Polygoni Multiflori Radix Preparat Delays Skin Aging by Inducing Mitophagy.
Topics: Adenine; Aging; Animals; Antioxidants; Apoptosis; Drugs, Chinese Herbal; Fallopia multiflora; Male; | 2021 |
De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
Topics: Adenine; Adenosine Triphosphate; Aging; Antiporters; Bone Diseases, Developmental; Calcium-Binding P | 2017 |
Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties.
Topics: Adenine; Aging; Animals; Cognition; Cognitive Dysfunction; eIF-2 Kinase; Enzyme Inhibitors; Hippocam | 2018 |
The RAGE/STAT5/autophagy axis regulates senescence in mesangial cells.
Topics: Adenine; Aging; Animals; Antigens, Neoplasm; Autophagy; Cellular Senescence; Gene Expression Regulat | 2019 |
A-to-I RNA editing does not change with age in the healthy male rat brain.
Topics: Adenine; Aging; Animals; Base Sequence; Brain; DNA Primers; Inosine; Male; Polymerase Chain Reaction | 2013 |
Predicting pediatric age-matched weight and body mass index.
Topics: Adenine; Adolescent; Aging; Body Mass Index; Body Weight; Child; Child, Preschool; Computer Simulati | 2014 |
Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients.
Topics: Adenine; Age of Onset; Aging; Amyotrophic Lateral Sclerosis; Autophagy; Bortezomib; C9orf72 Protein; | 2016 |
Gender and chronological age affect erythrocyte membrane oxidative indices in citrate phosphate dextrose adenine-formula 1 (CPDA-1) blood bank storage condition.
Topics: Adenine; Aging; Animals; Antioxidants; Blood Banking; Blood Preservation; Citrates; Erythrocyte Memb | 2016 |
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine; | 2017 |
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine; | 2017 |
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine; | 2017 |
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine; | 2017 |
Serological update and molecular characterization of Dirofilaria immitis in dogs, South Korea.
Topics: Adenine; Aging; Animals; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Enzyme-Linked Immu | 2010 |
Activation of wound healing in aged rats by altering the cellular mitogenic potential.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Age Factors; Aging; Animals; Cell Movement; Cell Proliferation | 2010 |
Disparate consequences of heat stress exposure during meiotic maturation: embryo development after chemical activation vs fertilization of bovine oocytes.
Topics: Actin Cytoskeleton; Adenine; Aging; Animals; Calcium; Calcium Ionophores; Cattle; Embryonic Developm | 2011 |
Reduced adenosine release from the aged mammalian heart.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adrenergic Antagonists; Agi | 2012 |
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; | 2013 |
[Effects of various gravistimuli on senescence of oat leaf segments].
Topics: Adenine; Aging; Avena; Chlorophyll; Gravitation; Hypergravity; Kinetin; Plant Growth Regulators; Pla | 1999 |
Influence of age on glycine and purine metabolism.
Topics: Adenine; Aging; Biochemical Phenomena; Glycine; Metabolic Networks and Pathways; Purines; RNA | 1962 |
Aging of cardiac myocytes in culture: oxidative stress, lipofuscin accumulation, and mitochondrial turnover.
Topics: Adenine; Aging; Animals; Animals, Newborn; Cells, Cultured; Image Processing, Computer-Assisted; Lip | 2004 |
Age-related changes in ischemic tolerance in male and female mouse hearts.
Topics: Adenine; Adenosine Diphosphate; Aging; Animals; Collagen; Coronary Vessels; Female; Heart; Hydro-Lya | 2005 |
Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy.
Topics: Adenine; Aging; Astrocytes; Autophagy; Cell Line; Cell Survival; Cellular Senescence; Cysteine Prote | 2005 |
The relationship between libido and testosterone levels in aging men.
Topics: Adenine; Adult; Aged; Aging; Cytosine; Follow-Up Studies; Guanine; Humans; Libido; Longitudinal Stud | 2006 |
Adenosine A2A receptor modulation of juvenile female rat skeletal muscle microvessel permeability.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cycl | 2006 |
Type and location of venous thromboembolism in patients with factor V Leiden or prothrombin G20210A and in those with no thrombophilia.
Topics: Adenine; Adolescent; Adult; Age Distribution; Age Factors; Aged; Aging; Child; Cohort Studies; Facto | 2007 |
Age-related changes in echocardiographic measurements: association with variation in the estrogen receptor-alpha gene.
Topics: Adenine; Adult; Aging; Cohort Studies; Dinucleotide Repeats; Echocardiography; Estrogen Receptor alp | 2007 |
CD4+ T cell evolution and predictors of its trend before and after tenofovir/didanosine backbone in the presence of sustained undetectable HIV plasma viral load.
Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; | 2007 |
Age related obesity-induced shortening of GLUT4 mRNA poly(A) tail length in rat gastrocnemius skeletal muscle.
Topics: Adenine; Adipose Tissue, White; Aging; Animals; Gene Expression Regulation; Glucose Transporter Type | 2007 |
Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration.
Topics: Adenine; Aged; Aging; Apolipoproteins E; DNA Primers; DNA, Mitochondrial; Female; Fluorescein Angiog | 2008 |
De novo biosynthesis of nucleotides and of nucleic acids in different regions of developing rat brain: effect of undernutrition.
Topics: Adenine; Aging; Animals; Brain; Brain Stem; Cerebellum; DNA; Formates; Kinetics; Nutrition Disorders | 1982 |
A cloning assay for 6-thioguanine resistance provides evidence against certain somatic mutational theories of aging.
Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Animals; Clone Cells; Drug Resistance; Hypoxanthi | 1984 |
Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Arginine; Blood-Brain Barrier; Brain; Butanols; Choline; | 1982 |
Inhibitory effect of a broad-spectrum antiviral agent, (S)-9-(2,3-dihydroxypropyl)adenine, on spermatogenesis in mice.
Topics: Adenine; Aging; Animals; Antiviral Agents; Blood Cell Count; Depression, Chemical; Male; Mice; Repro | 1981 |
Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult.
Topics: Adenine; Adenosine; Aging; Amino Acids; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Carbo | 1980 |
Plant growth hormone kinetin delays ageing, prolongs the lifespan and slows down development of the fruitfly Zaprionus paravittiger.
Topics: Adenine; Aging; Animals; Diptera; Female; Kinetin; Larva; Longevity; Male; Plant Growth Regulators; | 1995 |
Regulation of extracellular adenosine levels in the striatum of aging rats.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; A | 1995 |
Effect of age on cholesterol uptake and utilization by rat adrenals: I. Internalization of lipoprotein-derived cholesteryl esters.
Topics: Adenine; Adrenal Cortex; Aging; Animals; Anticholesteremic Agents; Cells, Cultured; Cholesterol; Cho | 1994 |
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA D | 1995 |
Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Base Sequence; DNA, Mitochondrial; Guanine; | 1993 |
Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Blood Pressure; Enzyme Inhibitor | 1998 |
[Analysis of transcript mutations due to transcriptional slippage in rat p53 tumor suppressor gene with the use of yeast functional assay].
Topics: Adenine; Aging; Animals; Cells, Cultured; DNA; DNA Mutational Analysis; Genes, p53; Mutation; Polyme | 1999 |
Age-related changes in A(1)-adenosine receptor-mediated bradycardia.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Bradycardia; Enzyme Inhibitors; | 2000 |
Transcriptional slippage of p53 gene enhanced by cellular damage in rat liver: monitoring the slippage by a yeast functional assay.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Aging; Animals; Aspartate Aminotransferases; Copper; Deoxyguan | 2000 |
The protection of rat liver autophagic proteolysis from the age-related decline co-varies with the duration of anti-ageing food restriction.
Topics: Adenine; Aging; Amino Acids; Animals; Autophagy; Cycloheximide; Diet; Food Deprivation; Hepatocytes; | 2001 |
Mitochondrial DNA repair of oxidative damage in mammalian cells.
Topics: Adenine; Aging; Animals; Cell Nucleus; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Repair; DNA-Bi | 2002 |
Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aging; Animals; Binding, Competitive; Carrier Proteins; Cat | 1976 |
Pentose shunt, phosphoribosylpyrophosphate generation and purine-phosphoribosyltransferases in erythrocytes of patients with polycythemia vera.
Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Erythrocytes; Hot Temperature; Humans; Hypoxanthi | 1975 |
[Regulation of age-dependent phenomena. Influence of C6-substituted purines on cell aggregation and cell migration in primary cultures of lense epithelial cells].
Topics: Adenine; Aging; Animals; Cattle; Cell Aggregation; Cell Movement; Cells, Cultured; Culture Media; De | 1975 |
Influence of hydrogen peroxide on adenine uptake by iris, ciliary epithelium and corneal endothelium.
Topics: Adenine; Aging; Amitrole; Animals; Anterior Chamber; Buthionine Sulfoximine; Catalase; Ciliary Body; | 1989 |
Mechanisms of ageing.
Topics: Adenine; Aging; Cytosine; Genetic Code; Genetics, Medical; Guanine; Humans; Thymine | 1970 |
Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alp | 1973 |
Effect of aging on the adenyl cyclase and phosphodiesterase activity of isolated fat cells of rat.
Topics: Adenine; Adenine Nucleotides; Adenylyl Cyclases; Adipose Tissue; Aging; Animals; Cyclic AMP; Enzymes | 1970 |
Induction of chick liver xanthine dehydrogenase by purines.
Topics: Adenine; Aging; Allopurinol; Animals; Carbon Isotopes; Chickens; Enzyme Induction; Hypoxanthines; Ke | 1972 |
The uptake of purines by rat brain in vivo and in vitro.
Topics: Adenine; Aging; Animals; Biological Transport; Brain; Carbon Isotopes; Chromatography; Dinitrophenol | 1973 |
Retardation of induced senescence of leaves from crop plants by benzimidazole and cytokinins.
Topics: Adenine; Aging; Amino Alcohols; Benzimidazoles; Benzyl Compounds; Chlorophyll; Edible Grain; Plant G | 1973 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation | 1971 |
[Survival determinations on thrombocyte preservatives].
Topics: Adenine; Aging; Blood Cell Count; Blood Platelets; Blood Preservation; Blood Transfusion; Centrifuga | 1967 |
Mobilization-independent effects of a cytokinin on senescing tomato leaves.
Topics: Adenine; Aging; Benzene Derivatives; Fruit; Plant Growth Regulators; Plants, Edible; Ribonucleases | 1968 |
DNA synthesis in the developing rat brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell-Free System | 1969 |
Inheritance of old age.
Topics: Adenine; Aging; Animals; Ascomycota; Drosophila; Molecular Biology; Mutation; Neurospora; Protein Bi | 1969 |
Errors in protein synthesis and clonal senescence in fungi.
Topics: Adenine; Aging; Ascomycota; Culture Media; Fluorouracil; Genetic Code; Genetics, Microbial; Mutation | 1969 |
The decrepitude of the rat brain with special reference to changes in nucleic acid.
Topics: Adenine; Aging; Animals; Brain Chemistry; Brain Stem; Cerebellum; Chromatography; Cytosine; Dienceph | 1966 |
Composition and content of RNA in neurons of rat hippocampus at different ages.
Topics: Adenine; Aging; Animals; Animals, Newborn; Chemical Phenomena; Chemistry; Cytosine; Electrophoresis; | 1966 |