Page last updated: 2024-10-16

adenine and Aging

adenine has been researched along with Aging in 71 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" For illustration, a pharmacodynamic model for leukopenia was constructed by stepwise linear regression from data of 41 patients with cancer treated with the drug amonafide."5.07Bootstrap validation of pharmacodynamic models defined via stepwise linear regression. ( Mick, R; Ratain, MJ, 1994)
" Previous studies have suggested a link between gene-specific reductions in adenosine to inosine RNA editing and aging in the human brain."3.79A-to-I RNA editing does not change with age in the healthy male rat brain. ( de Magalhães, JP; Holmes, AP; Merry, BJ; Wood, SH, 2013)
"Erythrocytes of patients with polycythemia vera exhibited increased activity of oxidative pentose shunt, accelerated generation of phosphoribosylpyrophosphate, increased incorporation of 14C-adenine into nucleotides, and increased activity and thermostability of adenine-phosphoribosyltransferase."3.65Pentose shunt, phosphoribosylpyrophosphate generation and purine-phosphoribosyltransferases in erythrocytes of patients with polycythemia vera. ( Boer, P; Brosh, S; de Vries, A; Elazar, E; Pinkhas, J; Sperling, O; Szeinberg, A, 1975)
"Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear."1.46Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states. ( Blanco, P; Bolen, CR; Chang, J; Daburon, S; Davis, MM; Déchanet-Merville, J; Dekker, CL; Douchet, I; Faustin, B; Fragiadakis, GK; Furman, D; Ganio, EA; Gaudilliere, B; Haddad, F; Jojic, V; Kuo, CJ; Lartigue, L; Moreau, JF; Nolan, GP; Spitzer, MH, 2017)
" We investigated whether tenofovir plus didanosine at a weight-adjusted dosage could be responsible for such an effect, and factors associated with CD4 + T cell count evolution under this combination."1.34CD4+ T cell evolution and predictors of its trend before and after tenofovir/didanosine backbone in the presence of sustained undetectable HIV plasma viral load. ( Antinori, A; Antonucci, F; Barreiro, P; Carosi, G; De Silvestri, A; El Hamad, I; Ladisa, N; Lapadula, G; Maggiolo, F; Mandalia, S; Maserati, R; Migliorino, G; Pierotti, P; Sighinolfi, L; Soriano, V; Suter, F; Torti, C, 2007)
"Obesity was accompanied by insulin resistance, and 65% reduction (P<0."1.34Age related obesity-induced shortening of GLUT4 mRNA poly(A) tail length in rat gastrocnemius skeletal muscle. ( Giannocco, G; Machado, UF; Nunes, MT; Seraphim, PM, 2007)
"Adenosine is an ubiquitously occurring endogenous nucleoside that via cell surface receptors exerts multiple antihypertensive actions, and mediates a number of biological responses that may reduce cardiovascular disease risk."1.30Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats. ( Jackson, EK; Kusaka, H; Li, P; Tofovic, SP, 1998)
"Adenosine binding was inhibited by only 30% under similar conditions."1.26Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues. ( Corbin, JD; Sugden, PH, 1976)
"The adenine action has been proved down to a concentration of 3 X 10(-6) M."1.25[Regulation of age-dependent phenomena. Influence of C6-substituted purines on cell aggregation and cell migration in primary cultures of lense epithelial cells]. ( Glässer, D; Iwig, M; Weber, E, 1975)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199025 (35.21)18.7374
1990's9 (12.68)18.2507
2000's15 (21.13)29.6817
2010's15 (21.13)24.3611
2020's7 (9.86)2.80

Authors

AuthorsStudies
Huang, J3
Yu, W1
He, Q1
He, X1
Yang, M3
Chen, W2
Han, W1
Tölle, M1
Henkel, C1
Herrmann, J1
Daniel, C1
Babic, M1
Xia, M1
Schulz, AM1
Amann, K1
van der Giet, M1
Schuchardt, M1
Chen, Y1
Wang, Q3
Luo, H1
Deng, S1
Tian, Y1
Wang, S1
Walmsley, S2
Clarke, R2
Lee, T2
Singer, J2
Cheung, AM2
Smaill, F2
De Pokomandy, A2
Trottier, S2
Messina, E2
Guaraldi, G2
Wang, M1
Wang, XF1
Li, YM1
Chen, N1
Fan, Y3
Huang, WK1
Hu, SF1
Rao, M1
Zhang, YZ1
Su, P1
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
Yan, Z1
Zhou, L1
Zhao, Y3
Wang, J7
Huang, L2
Hu, K1
Liu, H4
Wang, H3
Guo, Z1
Song, Y1
Huang, H4
Yang, R1
Owen, TW1
Al-Kaysi, RO1
Bardeen, CJ1
Cheng, Q1
Wu, S1
Cheng, T1
Zhou, X1
Wang, B4
Zhang, Q4
Wu, X2
Yao, Y3
Ochiai, T1
Ishiguro, H2
Nakano, R2
Kubota, Y2
Hara, M1
Sunada, K1
Hashimoto, K1
Kajioka, J1
Fujishima, A1
Jiao, J3
Gai, QY3
Wang, W2
Zang, YP2
Niu, LL2
Fu, YJ3
Wang, X4
Yao, LP1
Qin, QP1
Wang, ZY1
Liu, J4
Aleksic Sabo, V1
Knezevic, P1
Borges-Argáez, R1
Chan-Balan, R1
Cetina-Montejo, L1
Ayora-Talavera, G1
Sansores-Peraza, P1
Gómez-Carballo, J1
Cáceres-Farfán, M1
Jang, J1
Akin, D1
Bashir, R1
Yu, Z1
Zhu, J2
Jiang, H1
He, C2
Xiao, Z1
Xu, J2
Sun, Q1
Han, D1
Lei, H1
Zhao, K2
Zhu, L1
Li, X4
Fu, H2
Wilson, BK1
Step, DL1
Maxwell, CL1
Gifford, CA1
Richards, CJ1
Krehbiel, CR1
Warner, JM1
Doerr, AJ1
Erickson, GE1
Guretzky, JA1
Rasby, RJ1
Watson, AK1
Klopfenstein, TJ1
Sun, Y4
Liu, Z3
Pham, TD1
Lee, BK1
Yang, FC1
Wu, KH1
Lin, WP1
Hu, MK1
Lin, L3
Shao, J1
Sun, M1
Xu, G1
Zhang, X6
Xu, N1
Wang, R1
Liu, S1
He, H1
Dong, X2
Yang, Q1
Duan, S1
Yu, Y2
Han, J2
Zhang, C5
Chen, L2
Yang, X1
Li, W3
Wang, T2
Campbell, DA1
Gao, K1
Zager, RA1
Johnson, ACM1
Guillem, A1
Keyser, J1
Singh, B1
Steubl, D1
Schneider, MP1
Meiselbach, H1
Nadal, J1
Schmid, MC1
Saritas, T1
Krane, V1
Sommerer, C1
Baid-Agrawal, S1
Voelkl, J1
Kotsis, F1
Köttgen, A1
Eckardt, KU1
Scherberich, JE1
Li, H4
Yao, L2
Sun, L3
Zhu, Z1
Naren, N1
Zhang, XX2
Gentile, GL1
Rupert, AS1
Carrasco, LI1
Garcia, EM1
Kumar, NG1
Walsh, SW1
Jefferson, KK1
Guest, RL1
Samé Guerra, D1
Wissler, M1
Grimm, J1
Silhavy, TJ1
Lee, JH2
Yoo, JS1
Kim, Y1
Kim, JS2
Lee, EJ1
Roe, JH1
Delorme, M1
Bouchard, PA1
Simon, M1
Simard, S1
Lellouche, F1
D'Urzo, KA1
Mok, F1
D'Urzo, AD1
Koneru, B1
Lopez, G1
Farooqi, A1
Conkrite, KL1
Nguyen, TH1
Macha, SJ1
Modi, A1
Rokita, JL1
Urias, E1
Hindle, A1
Davidson, H1
Mccoy, K1
Nance, J1
Yazdani, V1
Irwin, MS1
Yang, S2
Wheeler, DA1
Maris, JM1
Diskin, SJ1
Reynolds, CP1
Abhilash, L1
Kalliyil, A1
Sheeba, V1
Hartley, AM2
Meunier, B2
Pinotsis, N1
Maréchal, A2
Xu, JY1
Genko, N1
Haraux, F1
Rich, PR1
Kamalanathan, M1
Doyle, SM1
Xu, C1
Achberger, AM1
Wade, TL1
Schwehr, K1
Santschi, PH1
Sylvan, JB1
Quigg, A1
Leong, W1
Xu, W2
Gao, S1
Zhai, X1
Wang, C2
Gilson, E1
Ye, J1
Lu, Y1
Yan, R1
Zhang, Y6
Hu, Z1
You, Q1
Cai, Q1
Yang, D1
Gu, S1
Dai, H1
Zhao, X1
Gui, C1
Gui, J1
Wu, PK1
Hong, SK1
Starenki, D1
Oshima, K1
Shao, H1
Gestwicki, JE1
Tsai, S1
Park, JI1
Wang, Y7
Zhao, R1
Gu, Z1
Dong, C2
Guo, G1
Li, L4
Barrett, HE1
Meester, EJ1
van Gaalen, K1
van der Heiden, K1
Krenning, BJ1
Beekman, FJ1
de Blois, E1
de Swart, J1
Verhagen, HJ1
Maina, T1
Nock, BA1
Norenberg, JP1
de Jong, M1
Gijsen, FJH1
Bernsen, MR1
Martínez-Milla, J1
Galán-Arriola, C1
Carnero, M1
Cobiella, J1
Pérez-Camargo, D1
Bautista-Hernández, V1
Rigol, M1
Solanes, N1
Villena-Gutierrez, R1
Lobo, M1
Mateo, J1
Vilchez-Tschischke, JP1
Salinas, B1
Cussó, L1
López, GJ1
Fuster, V1
Desco, M1
Sanchez-González, J1
Ibanez, B1
van den Berg, P1
Schweitzer, DH1
van Haard, PMM1
Geusens, PP1
van den Bergh, JP1
Zhu, X2
Huang, X2
Xu, H2
Yang, G2
Lin, Z1
Salem, HF1
Nafady, MM1
Kharshoum, RM1
Abd El-Ghafar, OA1
Farouk, HO1
Domiciano, D1
Nery, FC1
de Carvalho, PA1
Prudente, DO1
de Souza, LB1
Chalfun-Júnior, A1
Paiva, R1
Marchiori, PER1
Lu, M2
An, Z1
Jiang, J2
Li, J7
Du, S1
Zhou, H1
Cui, J1
Wu, W1
Liu, Y7
Song, J1
Lian, Q1
Uddin Ahmad, Z1
Gang, DD1
Konggidinata, MI1
Gallo, AA1
Zappi, ME1
Yang, TWW1
Johari, Y1
Burton, PR1
Earnest, A1
Shaw, K1
Hare, JL1
Brown, WA1
Kim, GA1
Han, S1
Choi, GH1
Choi, J1
Lim, YS1
Gallo, A1
Cancelli, C1
Ceron, E1
Covino, M1
Capoluongo, E1
Pocino, K1
Ianiro, G1
Cammarota, G1
Gasbarrini, A1
Montalto, M1
Somasundar, Y1
Lu, IC1
Mills, MR1
Qian, LY1
Olivares, X1
Ryabov, AD1
Collins, TJ1
Zhao, L1
Doddipatla, S1
Thomas, AM1
Nikolayev, AA1
Galimova, GR1
Azyazov, VN1
Mebel, AM1
Kaiser, RI1
Guo, S1
Yang, P1
Yu, X2
Wu, Y2
Zhang, H1
Yu, B2
Han, B1
George, MW1
Moor, MB1
Bonny, O1
Langenberg, E1
Paik, H1
Smith, EH1
Nair, HP1
Hanke, I1
Ganschow, S1
Catalan, G1
Domingo, N1
Schlom, DG1
Assefa, MK1
Wu, G2
Hayton, TW1
Becker, B1
Enikeev, D1
Netsch, C1
Gross, AJ1
Laukhtina, E1
Glybochko, P1
Rapoport, L1
Herrmann, TRW1
Taratkin, M1
Dai, W1
Shi, J2
Carreno, J1
Kloner, RA1
Pickersgill, NA1
Vetter, JM1
Kim, EH1
Cope, SJ1
Du, K1
Venkatesh, R1
Giardina, JD1
Saad, NES1
Bhayani, SB1
Figenshau, RS1
Eriksson, J1
Landfeldt, E1
Ireland, S1
Jackson, C1
Wyatt, E1
Gaudig, M1
Stancill, JS1
Happ, JT1
Broniowska, KA1
Hogg, N1
Corbett, JA1
Tang, LF1
Bi, YL1
Sun, YB1
Wang, AL1
Xiao, BH1
Wang, LF1
Qiu, SW1
Guo, SW1
Wáng, YXJ1
Sun, J2
Chu, S1
Pan, Q1
Li, D2
Zheng, S2
Ma, L1
Wang, L4
Hu, T1
Wang, F1
Han, Z1
Yin, Z1
Ge, X1
Xie, K1
Lei, P1
Dias-Santagata, D1
Lennerz, JK1
Sadow, PM1
Frazier, RP1
Govinda Raju, S1
Henry, D1
Chung, T1
Kherani, J1
Rothenberg, SM1
Wirth, LJ1
Marti, CN1
Choi, NG1
Bae, SJ1
Ni, L1
Luo, X1
Dai, T1
Yang, Y3
Lee, R1
Fleischer, AS1
Wemhoff, AP1
Ford, CR1
Kleppinger, EL1
Helms, K1
Bush, AA1
Luna-Abanto, J1
García Ruiz, L1
Laura Martinez, J1
Álvarez Larraondo, M1
Villoslada Terrones, V1
Dukic, L1
Maric, N1
Simundic, AM1
Chogtu, B1
Ommurugan, B1
Thomson, SR1
Kalthur, SG1
Benidir, M1
El Massoudi, S1
El Ghadraoui, L1
Lazraq, A1
Benjelloun, M1
Errachidi, F1
Cassar, M1
Law, AD1
Chow, ES1
Giebultowicz, JM1
Kretzschmar, D1
Salonurmi, T1
Nabil, H1
Ronkainen, J1
Hyötyläinen, T1
Hautajärvi, H1
Savolainen, MJ1
Tolonen, A1
Orešič, M1
Känsäkoski, P1
Rysä, J1
Hakkola, J1
Hukkanen, J1
Zhu, N1
Li, Y4
Du, Q1
Hao, P1
Cao, X1
Li, CX1
Zhao, S1
Luo, XM1
Feng, JX1
Gonzalez-Cotto, M1
Guo, L1
Karwan, M1
Sen, SK1
Barb, J1
Collado, CJ1
Elloumi, F1
Palmieri, EM1
Boelte, K1
Kolodgie, FD1
Finn, AV1
Biesecker, LG1
McVicar, DW1
Qu, F1
Deng, Z1
Xie, Y2
Tang, J3
Chen, Z2
Luo, W1
Xiong, D1
Zhao, D1
Fang, J1
Zhou, Z1
Niu, PP1
Song, B1
Xu, YM1
Zhang, Z2
Qiu, N1
Yin, J1
Zhang, J3
Guo, W1
Liu, M2
Liu, T2
Chen, D5
Luo, K1
He, Z2
Zheng, G1
Xu, F1
Sun, W1
Yin, F1
van Hest, JCM1
Du, L2
Shi, X1
Kang, S1
Duan, W1
Zhang, S2
Feng, J2
Qi, N1
Shen, G1
Ren, H1
Shang, Q1
Zhao, W2
Yang, Z2
Jiang, X3
Alame, M1
Cornillot, E1
Cacheux, V1
Tosato, G1
Four, M1
De Oliveira, L1
Gofflot, S1
Delvenne, P1
Turtoi, E1
Cabello-Aguilar, S1
Nishiyama, M1
Turtoi, A1
Costes-Martineau, V1
Colinge, J1
Guo, Q1
Quan, M1
Dong, J1
Bai, J1
Han, R1
Cai, Y1
Lv, YQ1
Chen, Q1
Lyu, HD1
Deng, L1
Zhou, D1
Xiao, X1
De Langhe, S1
Billadeau, DD1
Lou, Z1
Zhang, JS1
Xue, Z1
Shen, XD1
Gao, F1
Busuttil, RW1
Kupiec-Weglinski, JW1
Ji, H1
Otano, I1
Alvarez, M1
Minute, L1
Ochoa, MC1
Migueliz, I1
Molina, C1
Azpilikueta, A1
de Andrea, CE1
Etxeberria, I1
Sanmamed, MF1
Teijeira, Á1
Berraondo, P1
Melero, I1
Zhong, Z1
Xie, X1
Yu, Q1
Zhou, C1
Liu, C2
Liu, W1
Yin, Y1
Li, CW1
Hsu, JL1
Zhou, Q1
Hu, B1
Fu, P1
Atyah, M1
Ma, Q2
Xu, Y1
Dong, Q1
Hung, MC1
Ren, N1
Huang, P1
Liao, R1
Chen, X3
Cao, Q1
Yuan, X1
Nie, W1
Yang, J2
Shao, B1
Ma, X1
Bi, Z1
Liang, X1
Tie, Y1
Mo, F1
Xie, D1
Wei, Y1
Wei, X2
Dokla, EME1
Fang, CS1
Chu, PC1
Chang, CS1
Abouzid, KAM1
Chen, CS1
Blaszczyk, R1
Brzezinska, J1
Dymek, B1
Stanczak, PS1
Mazurkiewicz, M1
Olczak, J1
Nowicka, J1
Dzwonek, K1
Zagozdzon, A1
Golab, J1
Golebiowski, A1
Xin, Z1
Himmelbauer, MK1
Jones, JH1
Enyedy, I1
Gilfillan, R1
Hesson, T1
King, K1
Marcotte, DJ1
Murugan, P1
Santoro, JC1
Gonzalez-Lopez de Turiso, F1
Pedron, J1
Boudot, C1
Brossas, JY1
Pinault, E1
Bourgeade-Delmas, S1
Sournia-Saquet, A1
Boutet-Robinet, E1
Destere, A1
Tronnet, A1
Bergé, J1
Bonduelle, C1
Deraeve, C1
Pratviel, G1
Stigliani, JL1
Paris, L1
Mazier, D1
Corvaisier, S1
Since, M1
Malzert-Fréon, A1
Wyllie, S1
Milne, R1
Fairlamb, AH1
Valentin, A1
Courtioux, B1
Verhaeghe, P1
Fang, X1
Gao, M1
Gao, H1
Bi, W1
Tang, H1
Cui, Y1
Zhang, L3
Fan, H1
Yu, H1
Mathison, CJN1
Chianelli, D1
Rucker, PV1
Nelson, J1
Roland, J1
Huang, Z2
Xie, YF1
Epple, R1
Bursulaya, B1
Lee, C1
Gao, MY1
Shaffer, J1
Briones, S1
Sarkisova, Y1
Galkin, A1
Li, N1
Li, C2
Hua, S1
Kasibhatla, S1
Kinyamu-Akunda, J1
Kikkawa, R1
Molteni, V1
Tellew, JE1
Jin, X1
Pang, B1
Liu, Q2
Liu, X4
Huang, Y2
Josephine Fauci, A1
Ma, Y1
Soo Lee, M1
Yuan, W1
Gao, R1
Qi, H1
Zheng, W1
Yang, F2
Chua, H1
Wang, K1
Ou, Y1
Huang, M1
Zhu, Y1
Yu, J1
Tian, J1
Zhao, M1
Hu, J1
Yao, C1
Zhang, B1
Usawachintachit, M1
Tzou, DT1
Washington, SL1
Hu, W1
Chi, T1
Sorensen, MD1
Bailey, MR1
Hsi, RS1
Cunitz, BW1
Simon, J1
Wang, YN1
Dunmire, BL1
Paun, M1
Starr, F1
Lu, W1
Evan, AP1
Harper, JD1
Han, G1
Rodrigues, AE1
Fouladvand, F1
Falahi, E1
Asbaghi, O1
Abbasnezhad, A1
Anigboro, AA1
Avwioroko, OJ1
Cholu, CO1
Sonei, A1
Fazelipour, S1
Kanaani, L1
Jahromy, MH1
Jo, K1
Hong, KB1
Suh, HJ1
Park, JH1
Shin, E1
Park, E1
Kouakou-Kouamé, CA1
N'guessan, FK1
Montet, D1
Djè, MK1
Kim, GD1
González-Fernández, D1
Pons, EDC1
Rueda, D1
Sinisterra, OT1
Murillo, E1
Scott, ME1
Koski, KG1
Shete, PB1
Gonzales, R1
Ackerman, S1
Cattamanchi, A1
Handley, MA1
Li, XX1
Xiao, SZ1
Gu, FF1
He, WP1
Ni, YX1
Han, LZ1
Heffernan, JK1
Valgepea, K1
de Souza Pinto Lemgruber, R1
Casini, I1
Plan, M1
Tappel, R1
Simpson, SD1
Köpke, M1
Nielsen, LK1
Marcellin, E1
Cen, YK1
Lin, JG1
Wang, YL1
Wang, JY1
Liu, ZQ1
Zheng, YG1
Spirk, D1
Noll, S1
Burnier, M1
Rimoldi, S1
Noll, G1
Sudano, I1
Penzhorn, BL1
Oosthuizen, MC1
Kobos, LM1
Alqatani, S1
Ferreira, CR1
Aryal, UK1
Hedrick, V1
Sobreira, TJP1
Shannahan, JH1
Gale, P1
Singhroy, DN1
MacLean, E1
Kohli, M1
Lessem, E1
Branigan, D1
England, K1
Suleiman, K1
Drain, PK1
Ruhwald, M1
Schumacher, S1
Denkinger, CM1
Waning, B1
Van Gemert, W1
Pai, M1
Myers, RK1
Bonsu, JM1
Carey, ME1
Yerys, BE1
Mollen, CJ1
Curry, AE1
Douglas, TA1
Alinezhadbalalami, N1
Balani, N1
Schmelz, EM1
Davalos, RV1
Kamaldinov, T1
Erndt-Marino, J1
Levin, M1
Kaplan, DL1
Hahn, MS1
Heidarimoghadam, R1
Farmany, A1
Lee, JJ1
Kang, J1
Park, S1
Cho, JH1
Oh, S1
Park, DJ1
Perez-Maldonado, R1
Cho, JY1
Park, IH1
Kim, HB1
Song, M1
Mfarrej, B1
Jofra, T1
Morsiani, C1
Gagliani, N1
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Qiao, L1
Xiong, X1
Peng, X1
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Duan, J1
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Zhao, FL1
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Wang, HY1
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Shasha, Y1
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Mengya, Y1
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Erman, H1
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Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Residual Immune Activation in HIV-infected Patients on Successful cART: Association Between Inflammasome Activation in Monocytes by Circulating Metabolites and Non AIDS Defining Comorbidities[NCT03191175]55 participants (Actual)Observational2017-07-03Completed
Immune Senescence in the Elderly: Comparison of Immune Responses to Influenza Vaccine In Adults of Different Ages[NCT01827462]Phase 4136 participants (Actual)Interventional2007-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Who Received the Influenza Vaccine

(NCT01827462)
Timeframe: Day 0 annually while on study

InterventionParticipants (Count of Participants)
18-30 Years Old at Enrollment59
60-79 Years Old at Enrollment37
80-100 Years Old at Enrollment40

Reviews

4 reviews available for adenine and Aging

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Endoplasmic reticulum proteostasis impairment in aging.
    Aging cell, 2017, Volume: 16, Issue:4

    Topics: Adenine; Aging; Animals; Brain; Caenorhabditis elegans; Drosophila melanogaster; Endoplasmic Reticul

2017
Base excision repair in nuclear and mitochondrial DNA.
    Progress in nucleic acid research and molecular biology, 2001, Volume: 68

    Topics: Adenine; Aging; Animals; Base Sequence; Cell Line; Cell Nucleus; Cell-Free System; DNA; DNA Damage;

2001
Maturation-inducing substance in starfishes.
    International review of cytology, 1973, Volume: 35

    Topics: Adenine; Aging; Chemical Phenomena; Chemistry; Drug Stability; Female; Fertility; Germ Cells; Gonads

1973

Trials

3 trials available for adenine and Aging

ArticleYear
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
    AIDS research and human retroviruses, 2023, Volume: 39, Issue:4

    Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged

2023
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
    AIDS research and human retroviruses, 2023, Volume: 39, Issue:4

    Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged

2023
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
    AIDS research and human retroviruses, 2023, Volume: 39, Issue:4

    Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged

2023
BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period.
    AIDS research and human retroviruses, 2023, Volume: 39, Issue:4

    Topics: Adenine; Aging; Anti-HIV Agents; Bone Density; COVID-19; Female; HIV Infections; Humans; Middle Aged

2023
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Bootstrap validation of pharmacodynamic models defined via stepwise linear regression.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:2

    Topics: Acetylation; Adenine; Aging; Female; Humans; Imides; Isoquinolines; Leukocyte Count; Leukopenia; Mal

1994

Other Studies

65 other studies available for adenine and Aging

ArticleYear
Autophagy facilitates age-related cell apoptosis-a new insight from senile cataract.
    Cell death & disease, 2022, 01-10, Volume: 13, Issue:1

    Topics: Adenine; Adult; Aged; Aging; Apoptosis; Autophagy; Cataract; Cell Survival; Cells, Cultured; Cellula

2022
Uremic mouse model to study vascular calcification and "inflamm-aging".
    Journal of molecular medicine (Berlin, Germany), 2022, Volume: 100, Issue:9

    Topics: Adenine; Aging; Animals; Disease Models, Animal; Inflammation; Kidney Failure, Chronic; Mice; Rats;

2022
Mechanisms of the ethanol extract of
    Food & function, 2022, Oct-03, Volume: 13, Issue:19

    Topics: Adenine; Aging; Amino Acids; Animals; Antioxidants; Catalase; Cholic Acid; Drosophila; Ethanol; Free

2022
Cross-talk between autophagy and apoptosis regulates testicular injury/recovery induced by cadmium via PI3K with mTOR-independent pathway.
    Cell death & disease, 2020, 01-22, Volume: 11, Issue:1

    Topics: Adenine; Aging; Animals; Apoptosis; Autophagy; Cadmium; Cell Line; Male; Models, Biological; Oxidati

2020
Renal Aging Resembles a Continuum Between Normal and Diseased Kidneys That Potentiates Inflammatory Response to Injury.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2021, 02-25, Volume: 76, Issue:3

    Topics: Adenine; Aging; Animals; Cytokines; Disease Models, Animal; Inflammation; Kidney Diseases; Male; Mic

2021
Polygoni Multiflori Radix Preparat Delays Skin Aging by Inducing Mitophagy.
    BioMed research international, 2021, Volume: 2021

    Topics: Adenine; Aging; Animals; Antioxidants; Apoptosis; Drugs, Chinese Herbal; Fallopia multiflora; Male;

2021
De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
    American journal of human genetics, 2017, Nov-02, Volume: 101, Issue:5

    Topics: Adenine; Adenosine Triphosphate; Aging; Antiporters; Bone Diseases, Developmental; Calcium-Binding P

2017
Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018, 01-17, Volume: 38, Issue:3

    Topics: Adenine; Aging; Animals; Cognition; Cognitive Dysfunction; eIF-2 Kinase; Enzyme Inhibitors; Hippocam

2018
The RAGE/STAT5/autophagy axis regulates senescence in mesangial cells.
    Cellular signalling, 2019, Volume: 62

    Topics: Adenine; Aging; Animals; Antigens, Neoplasm; Autophagy; Cellular Senescence; Gene Expression Regulat

2019
A-to-I RNA editing does not change with age in the healthy male rat brain.
    Biogerontology, 2013, Volume: 14, Issue:4

    Topics: Adenine; Aging; Animals; Base Sequence; Brain; DNA Primers; Inosine; Male; Polymerase Chain Reaction

2013
Predicting pediatric age-matched weight and body mass index.
    The AAPS journal, 2014, Volume: 16, Issue:6

    Topics: Adenine; Adolescent; Aging; Body Mass Index; Body Weight; Child; Child, Preschool; Computer Simulati

2014
Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Adenine; Age of Onset; Aging; Amyotrophic Lateral Sclerosis; Autophagy; Bortezomib; C9orf72 Protein;

2016
Gender and chronological age affect erythrocyte membrane oxidative indices in citrate phosphate dextrose adenine-formula 1 (CPDA-1) blood bank storage condition.
    General physiology and biophysics, 2016, Volume: 35, Issue:3

    Topics: Adenine; Aging; Animals; Antioxidants; Blood Banking; Blood Preservation; Citrates; Erythrocyte Memb

2016
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
    Nature medicine, 2017, Volume: 23, Issue:2

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine;

2017
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
    Nature medicine, 2017, Volume: 23, Issue:2

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine;

2017
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
    Nature medicine, 2017, Volume: 23, Issue:2

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine;

2017
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
    Nature medicine, 2017, Volume: 23, Issue:2

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Blood Platelets; Blood Pressure; Caffeine;

2017
Serological update and molecular characterization of Dirofilaria immitis in dogs, South Korea.
    Research in veterinary science, 2010, Volume: 88, Issue:3

    Topics: Adenine; Aging; Animals; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Enzyme-Linked Immu

2010
Activation of wound healing in aged rats by altering the cellular mitogenic potential.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2010, Volume: 65, Issue:7

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Age Factors; Aging; Animals; Cell Movement; Cell Proliferation

2010
Disparate consequences of heat stress exposure during meiotic maturation: embryo development after chemical activation vs fertilization of bovine oocytes.
    Reproduction (Cambridge, England), 2011, Volume: 142, Issue:6

    Topics: Actin Cytoskeleton; Adenine; Aging; Animals; Calcium; Calcium Ionophores; Cattle; Embryonic Developm

2011
Reduced adenosine release from the aged mammalian heart.
    Journal of cellular physiology, 2012, Volume: 227, Issue:11

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adrenergic Antagonists; Agi

2012
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
    The Journal of infectious diseases, 2013, Volume: 207, Issue:7

    Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies;

2013
[Effects of various gravistimuli on senescence of oat leaf segments].
    Uchu Seibutsu Kagaku, 1999, Volume: 13, Issue:3

    Topics: Adenine; Aging; Avena; Chlorophyll; Gravitation; Hypergravity; Kinetin; Plant Growth Regulators; Pla

1999
Influence of age on glycine and purine metabolism.
    Archives of biochemistry and biophysics, 1962, Volume: 99

    Topics: Adenine; Aging; Biochemical Phenomena; Glycine; Metabolic Networks and Pathways; Purines; RNA

1962
Aging of cardiac myocytes in culture: oxidative stress, lipofuscin accumulation, and mitochondrial turnover.
    Annals of the New York Academy of Sciences, 2004, Volume: 1019

    Topics: Adenine; Aging; Animals; Animals, Newborn; Cells, Cultured; Image Processing, Computer-Assisted; Lip

2004
Age-related changes in ischemic tolerance in male and female mouse hearts.
    Journal of molecular and cellular cardiology, 2005, Volume: 38, Issue:2

    Topics: Adenine; Adenosine Diphosphate; Aging; Animals; Collagen; Coronary Vessels; Female; Heart; Hydro-Lya

2005
Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy.
    Biogerontology, 2005, Volume: 6, Issue:1

    Topics: Adenine; Aging; Astrocytes; Autophagy; Cell Line; Cell Survival; Cellular Senescence; Cysteine Prote

2005
The relationship between libido and testosterone levels in aging men.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenine; Adult; Aged; Aging; Cytosine; Follow-Up Studies; Guanine; Humans; Libido; Longitudinal Stud

2006
Adenosine A2A receptor modulation of juvenile female rat skeletal muscle microvessel permeability.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cycl

2006
Type and location of venous thromboembolism in patients with factor V Leiden or prothrombin G20210A and in those with no thrombophilia.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:1

    Topics: Adenine; Adolescent; Adult; Age Distribution; Age Factors; Aged; Aging; Child; Cohort Studies; Facto

2007
Age-related changes in echocardiographic measurements: association with variation in the estrogen receptor-alpha gene.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:5

    Topics: Adenine; Adult; Aging; Cohort Studies; Dinucleotide Repeats; Echocardiography; Estrogen Receptor alp

2007
CD4+ T cell evolution and predictors of its trend before and after tenofovir/didanosine backbone in the presence of sustained undetectable HIV plasma viral load.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:6

    Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count;

2007
Age related obesity-induced shortening of GLUT4 mRNA poly(A) tail length in rat gastrocnemius skeletal muscle.
    Molecular and cellular endocrinology, 2007, Sep-30, Volume: 276, Issue:1-2

    Topics: Adenine; Adipose Tissue, White; Aging; Animals; Gene Expression Regulation; Glucose Transporter Type

2007
Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration.
    PloS one, 2008, May-07, Volume: 3, Issue:5

    Topics: Adenine; Aged; Aging; Apolipoproteins E; DNA Primers; DNA, Mitochondrial; Female; Fluorescein Angiog

2008
De novo biosynthesis of nucleotides and of nucleic acids in different regions of developing rat brain: effect of undernutrition.
    Journal of neuroscience research, 1982, Volume: 8, Issue:1

    Topics: Adenine; Aging; Animals; Brain; Brain Stem; Cerebellum; DNA; Formates; Kinetics; Nutrition Disorders

1982
A cloning assay for 6-thioguanine resistance provides evidence against certain somatic mutational theories of aging.
    Journal of cellular physiology, 1984, Volume: 121, Issue:2

    Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Animals; Clone Cells; Drug Resistance; Hypoxanthi

1984
Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain.
    Pediatric research, 1982, Volume: 16, Issue:4 Pt 1

    Topics: Adenine; Aging; Animals; Animals, Newborn; Arginine; Blood-Brain Barrier; Brain; Butanols; Choline;

1982
Inhibitory effect of a broad-spectrum antiviral agent, (S)-9-(2,3-dihydroxypropyl)adenine, on spermatogenesis in mice.
    Toxicology and applied pharmacology, 1981, Volume: 59, Issue:3

    Topics: Adenine; Aging; Animals; Antiviral Agents; Blood Cell Count; Depression, Chemical; Male; Mice; Repro

1981
Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult.
    Journal of neurochemistry, 1980, Volume: 34, Issue:1

    Topics: Adenine; Adenosine; Aging; Amino Acids; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Carbo

1980
Plant growth hormone kinetin delays ageing, prolongs the lifespan and slows down development of the fruitfly Zaprionus paravittiger.
    Biochemical and biophysical research communications, 1995, Nov-22, Volume: 216, Issue:3

    Topics: Adenine; Aging; Animals; Diptera; Female; Kinetin; Larva; Longevity; Male; Plant Growth Regulators;

1995
Regulation of extracellular adenosine levels in the striatum of aging rats.
    Brain research, 1995, Jun-26, Volume: 684, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; A

1995
Effect of age on cholesterol uptake and utilization by rat adrenals: I. Internalization of lipoprotein-derived cholesteryl esters.
    Mechanisms of ageing and development, 1994, Nov-25, Volume: 77, Issue:1

    Topics: Adenine; Adrenal Cortex; Aging; Animals; Anticholesteremic Agents; Cells, Cultured; Cholesterol; Cho

1994
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
    Chemico-biological interactions, 1995, Volume: 94, Issue:2

    Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA D

1995
Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans.
    Biochemical and biophysical research communications, 1993, Sep-15, Volume: 195, Issue:2

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Aging; Animals; Base Sequence; DNA, Mitochondrial; Guanine;

1993
Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Blood Pressure; Enzyme Inhibitor

1998
[Analysis of transcript mutations due to transcriptional slippage in rat p53 tumor suppressor gene with the use of yeast functional assay].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1999, Volume: 74, Issue:3

    Topics: Adenine; Aging; Animals; Cells, Cultured; DNA; DNA Mutational Analysis; Genes, p53; Mutation; Polyme

1999
Age-related changes in A(1)-adenosine receptor-mediated bradycardia.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Bradycardia; Enzyme Inhibitors;

2000
Transcriptional slippage of p53 gene enhanced by cellular damage in rat liver: monitoring the slippage by a yeast functional assay.
    Mutation research, 2000, Feb-14, Volume: 447, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Aging; Animals; Aspartate Aminotransferases; Copper; Deoxyguan

2000
The protection of rat liver autophagic proteolysis from the age-related decline co-varies with the duration of anti-ageing food restriction.
    Experimental gerontology, 2001, Volume: 36, Issue:3

    Topics: Adenine; Aging; Amino Acids; Animals; Autophagy; Cycloheximide; Diet; Food Deprivation; Hepatocytes;

2001
Mitochondrial DNA repair of oxidative damage in mammalian cells.
    Gene, 2002, Mar-06, Volume: 286, Issue:1

    Topics: Adenine; Aging; Animals; Cell Nucleus; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Repair; DNA-Bi

2002
Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues.
    The Biochemical journal, 1976, Volume: 159, Issue:2

    Topics: Adenine; Adenine Nucleotides; Adenosine; Aging; Animals; Binding, Competitive; Carrier Proteins; Cat

1976
Pentose shunt, phosphoribosylpyrophosphate generation and purine-phosphoribosyltransferases in erythrocytes of patients with polycythemia vera.
    Acta haematologica, 1975, Volume: 54, Issue:2

    Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Erythrocytes; Hot Temperature; Humans; Hypoxanthi

1975
[Regulation of age-dependent phenomena. Influence of C6-substituted purines on cell aggregation and cell migration in primary cultures of lense epithelial cells].
    Zeitschrift fur Alternsforschung, 1975, Volume: 30, Issue:4

    Topics: Adenine; Aging; Animals; Cattle; Cell Aggregation; Cell Movement; Cells, Cultured; Culture Media; De

1975
Influence of hydrogen peroxide on adenine uptake by iris, ciliary epithelium and corneal endothelium.
    Lens and eye toxicity research, 1989, Volume: 6, Issue:3

    Topics: Adenine; Aging; Amitrole; Animals; Anterior Chamber; Buthionine Sulfoximine; Catalase; Ciliary Body;

1989
Mechanisms of ageing.
    Lancet (London, England), 1970, Nov-07, Volume: 2, Issue:7680

    Topics: Adenine; Aging; Cytosine; Genetic Code; Genetics, Medical; Guanine; Humans; Thymine

1970
Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.
    Molecular pharmacology, 1973, Volume: 9, Issue:6

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alp

1973
Effect of aging on the adenyl cyclase and phosphodiesterase activity of isolated fat cells of rat.
    Biochimica et biophysica acta, 1970, May-12, Volume: 208, Issue:2

    Topics: Adenine; Adenine Nucleotides; Adenylyl Cyclases; Adipose Tissue; Aging; Animals; Cyclic AMP; Enzymes

1970
Induction of chick liver xanthine dehydrogenase by purines.
    Archives of biochemistry and biophysics, 1972, Volume: 153, Issue:2

    Topics: Adenine; Aging; Allopurinol; Animals; Carbon Isotopes; Chickens; Enzyme Induction; Hypoxanthines; Ke

1972
The uptake of purines by rat brain in vivo and in vitro.
    Journal of neurochemistry, 1973, Volume: 20, Issue:4

    Topics: Adenine; Aging; Animals; Biological Transport; Brain; Carbon Isotopes; Chromatography; Dinitrophenol

1973
Retardation of induced senescence of leaves from crop plants by benzimidazole and cytokinins.
    Experimental gerontology, 1973, Volume: 8, Issue:4

    Topics: Adenine; Aging; Amino Alcohols; Benzimidazoles; Benzyl Compounds; Chlorophyll; Edible Grain; Plant G

1973
[Transmethylation processes in senile involution: a working hypothesis].
    Giornale di gerontologia, 1971, Volume: 19, Issue:9

    Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation

1971
[Survival determinations on thrombocyte preservatives].
    Bibliotheca haematologica, 1967, Volume: 27

    Topics: Adenine; Aging; Blood Cell Count; Blood Platelets; Blood Preservation; Blood Transfusion; Centrifuga

1967
Mobilization-independent effects of a cytokinin on senescing tomato leaves.
    Die Naturwissenschaften, 1968, Volume: 55, Issue:3

    Topics: Adenine; Aging; Benzene Derivatives; Fruit; Plant Growth Regulators; Plants, Edible; Ribonucleases

1968
DNA synthesis in the developing rat brain.
    Canadian journal of biochemistry, 1969, Volume: 47, Issue:1

    Topics: Adenine; Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell-Free System

1969
Inheritance of old age.
    Nature, 1969, Mar-29, Volume: 221, Issue:5187

    Topics: Adenine; Aging; Animals; Ascomycota; Drosophila; Molecular Biology; Mutation; Neurospora; Protein Bi

1969
Errors in protein synthesis and clonal senescence in fungi.
    Nature, 1969, Mar-29, Volume: 221, Issue:5187

    Topics: Adenine; Aging; Ascomycota; Culture Media; Fluorouracil; Genetic Code; Genetics, Microbial; Mutation

1969
The decrepitude of the rat brain with special reference to changes in nucleic acid.
    The Tohoku journal of experimental medicine, 1966, Jul-25, Volume: 89, Issue:3

    Topics: Adenine; Aging; Animals; Brain Chemistry; Brain Stem; Cerebellum; Chromatography; Cytosine; Dienceph

1966
Composition and content of RNA in neurons of rat hippocampus at different ages.
    Brain research, 1966, Volume: 2, Issue:3

    Topics: Adenine; Aging; Animals; Animals, Newborn; Chemical Phenomena; Chemistry; Cytosine; Electrophoresis;

1966