adenine has been researched along with African Sleeping Sickness in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Novel methods for treatment of African trypanosomiasis, caused by infection with Trypanosoma brucei are needed." | 1.39 | Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis. ( de Koning, HP; Eze, AA; Gustavsson, AL; Hammarström, LG; Lundbäck, T; Olivera, GC; Rottenberg, ME; Sjöberg, B; Svensson, R; Vodnala, SK; Yeheskieli, E, 2013) |
| "During the first stage of human African trypanosomiasis (HAT), Trypanosoma brucei gambiense is found mainly in the blood, and pentamidine treatment is used." | 1.35 | Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein. ( De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA, 2009) |
| "African sleeping sickness is caused by Trypanosoma brucei." | 1.35 | Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei. ( Fijolek, A; Hofer, A; Mäser, P; Mosimann, M; Rofougaran, R; Vodnala, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vodnala, SK | 1 |
| Lundbäck, T | 1 |
| Yeheskieli, E | 1 |
| Sjöberg, B | 1 |
| Gustavsson, AL | 1 |
| Svensson, R | 1 |
| Olivera, GC | 1 |
| Eze, AA | 1 |
| de Koning, HP | 3 |
| Hammarström, LG | 1 |
| Rottenberg, ME | 1 |
| Ranjbarian, F | 1 |
| Vodnala, M | 2 |
| Alzahrani, KJH | 1 |
| Ebiloma, GU | 1 |
| Hofer, A | 2 |
| Sanderson, L | 1 |
| Dogruel, M | 1 |
| Rodgers, J | 1 |
| Thomas, SA | 1 |
| Fijolek, A | 1 |
| Rofougaran, R | 1 |
| Mosimann, M | 1 |
| Mäser, P | 1 |
| Kaminsky, R | 1 |
| Zweygarth, E | 1 |
| De Clercq, E | 1 |
5 other studies available for adenine and African Sleeping Sickness
| Article | Year |
|---|---|
Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.
Topics: Animals; Cell Survival; Cells, Cultured; Deoxyadenosines; Dose-Response Relationship, Drug; Humans; | 2013 |
9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance.
Topics: Adenine; Adenosine Kinase; Animals; Antimetabolites; Drug Resistance; Mice; Purine-Nucleoside Phosph | 2017 |
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Bl | 2009 |
Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei.
Topics: Adenine; Adenosine Kinase; Animals; Antimetabolites; Catalysis; Guanosine Triphosphate; Humans; Leis | 2008 |
Antitrypanosomal activity of phosphonylmethoxyalkylpurines.
Topics: Adenine; Animals; Cidofovir; Cytosine; Female; Mice; Mice, Inbred BALB C; Organophosphonates; Organo | 1994 |