adenine has been researched along with Adult Fanconi Syndrome in 103 studies
Excerpt | Relevance | Reference |
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" He had been receiving low-dose adefovir dipivoxil (ADV) for the treatment of lamivudine-resistant chronic hepatitis B virus infection for eight years and subsequently developed severe hypophosphatemia and proximal renal tubule dysfunction." | 8.90 | Hypophosphatemic osteomalacia due to drug-induced Fanconi's syndrome associated with adefovir dipivoxil treatment for hepatitis B. ( Eguchi, H; Hiromatsu, Y; Kuwahara, R; Tani, J; Tsuruta, M, 2014) |
"This report suggests the possibility of severe tenofovir-induced nephrotoxicity with combined acute kidney injury, Fanconi syndrome, and nephrogenic diabetes insipidus in the absence of other provoking factors such as use with protease inhibitors or advanced HIV disease, chronic kidney disease, and age." | 8.31 | Fanconi syndrome, diabetes insipidus, and acute kidney injury due to tenofovir disoproxil fumarate: A case report. ( Gill, S; Kalinoski, T; Mehboob, G; Mpejane, O; Zilwa, N, 2023) |
"Adefovir dipivoxil (ADV) is one of the most important nucleostide analogues currently in use for the treatment of chronic hepatitis B virus (HBV) infection." | 7.91 | Low-dose adefovir dipivoxil-induced hypophosphatemia osteomalacia in five chronic hepatitis B virus-infected patients. Is low-dose adefovir dipivoxil-induced nephrotoxicity completely reversible? ( Dai, ZJ; Jin, J; Pan, YJ; Qian, YY; Ruan, LY; Shi, MT; Wu, CM; Zhu, YX, 2019) |
" He had been receiving adefovir dipivoxil (ADV) for the treatment of entecavir (ETV)-resistant chronic hepatitis B (CHB) for four years in his 8-year treatment of hepatocellular carcinoma (HCC), but was referred to our hospital after increased levels of bone pain in his ribs, knees, and ankles." | 7.91 | [Adefovir Dipivoxil-induced Fanconi's Syndrome and Osteomalacia Following Multiple Bone Fractures in a Patient with Chronic Hepatitis B]. ( Ikeda, A; Ikeda, F; Kanzaki, H; Kitamura, Y; Makita, T; Murakawa, K; Nishihara, S; Okada, H; Onishi, H; Sendo, T; Shiraha, H; Takaki, A; Takeuchi, Y; Tanaka, Y; Wada, N; Yasunaka, T, 2019) |
" She had a 7-year history of taking adefovir at 10 mg/day for chronic hepatitis B." | 7.88 | Adefovir-induced Fanconi syndrome associated with osteomalacia. ( Cha, SK; Cho, DH; Kim, HS; Kim, JH; Kim, WI; Kim, YJ; Lee, EY; Lee, JH; Lee, SM; Park, KS; Park, S, 2018) |
"An increasing number of case reports suggest that acquired renal Fanconi syndrome may be associated with prolonged use of adefovir against hepatitis B virus." | 7.85 | Nephrolithiasis and Osteomalacia associated with adefovir-induced Fanconi syndrome in a patient with hepatitis B. ( Lin, J; Zhang, D; Zhuo, Y, 2017) |
"In human immunodeficiency virus (HIV)-infected patients, tenofovir disoproxil fumarate (TDF) may cause hypophosphatemia leading to osteomalacia due to renal phosphate wasting." | 7.80 | Fibroblast growth factor 23 is elevated in tenofovir-related hypophosphatemia. ( Holmes, DT; Jiang, SY; Kendler, DL; Saeedi, R, 2014) |
"A 64-year-old woman was prescribed lamivudine and adefovir (ADV) for chronic hepatitis B." | 7.80 | [A case of chronic hepatitis B managed with continued adefovir despite treatment-related Fanconi syndrome and osteomalacia]. ( Asahina, Y; Iizuka, K; Iizuka, Y; Ito, E; Kobayashi, K; Mochizuki, N; Sakai, H; Watanabe, M, 2014) |
" Here, we describe two additional patients with chronic hepatitis B (CHB) who developed a TDF-induced Fanconi syndrome that reverted after TDF withdrawal and had viral replication fully suppressed upon switching to entecavir (ETV)." | 7.80 | Tenofovir-induced Fanconi syndrome in chronic hepatitis B monoinfected patients that reverted after tenofovir withdrawal. ( Brocchieri, A; Castelli, F; Colombo, M; Facchetti, F; Fugazza, A; Lampertico, P; Mangia, G; Spinetti, A; Viganò, M; Zaltron, S, 2014) |
"Tenofovir disoproxil fumarate (TDF) is increasingly used in patients with chronic hepatitis B (CHB) infection." | 7.79 | Tenofovir-associated Fanconi syndrome in patients with chronic hepatitis B monoinfection. ( Gracey, DM; McKenzie, P; Snelling, P; Strasser, SI, 2013) |
"We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia." | 7.78 | Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report. ( Arishima, Y; Hirotsu, M; Ishidou, Y; Kakoi, H; Kamizono, J; Komiya, S; Nagano, S; Nakamura, S; Saitoh, Y; Setoguchi, T; Tanaka, M; Yokouchi, M, 2012) |
"Adefovir dipivoxil is commonly used for treatment of chronic hepatitis B." | 7.77 | [Adefovir dipivoxil-induced Fanconi syndrome and hypophosphatemic osteomalacia associated with muscular weakness in a patient with chronic hepatitis B]. ( Dong, GF; Li, L; Xie, YS; Zhang, X, 2011) |
"We present 2 human immunodeficiency virus-infected patients with tenofovir disoproxil fumarate-induced Fanconi syndrome, leading to osteomalacia." | 7.77 | Tenofovir-induced Fanconi syndrome and osteomalacia in two HIV-infected patients: role of intracellular tenofovir diphosphate levels and review of the literature. ( Bronsveld, W; Haverkort, ME; Huitema, AD; Lips, P; Slieker, WA; ter Heine, R; van der Spek, BW, 2011) |
"Combination therapy with adefovir dipivoxil (ADV) and lamivudine (LAM) is recommended for patients infected with LAM-refractory hepatitis B virus (HBV)." | 7.76 | Add-on combination therapy with adefovir dipivoxil induces renal impairment in patients with lamivudine-refractory hepatitis B virus. ( Enomoto, M; Habu, D; Imanishi, Y; Iwai, S; Kawada, N; Kobayashi, S; Morikawa, H; Sakaguchi, H; Shiomi, S; Tamori, A, 2010) |
"We report 3 cases of patients with HIV/AIDS in whom Fanconi syndrome and nephrogenic diabetes insipidus developed secondary to use of an antiretroviral regimen containing tenofovir disoproxil fumarate and didanosine." | 7.75 | Proximal tubular dysfunction associated with tenofovir and didanosine causing Fanconi syndrome and diabetes insipidus: a report of 3 cases. ( Alvarez, S; Brumble, LM; Dwyer, JP; Irizarry-Alvarado, JM; Mendez, JC, 2009) |
"To determine the spectrum of clinical manifestations of hypokalemia associated with tenofovir, we reviewed all reports of grades 3/4 hypokalemia received by Gilead Sciences Department of Safety and Public Health." | 7.74 | Causes and consequences of hypokalemia in patients on tenofovir disoproxil fumarate. ( Curtis, S; Rooney, JF; Shepp, DH, 2007) |
"Tenofovir-related tubule damage characterized by Fanconi syndrome, renal insufficiency and nephrogenic diabetes insipidus has been reported in the adult HIV-infected population." | 7.73 | Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir. ( Hussain, S; Khayat, A; Rathore, MH; Tolaymat, A, 2006) |
"Tenofovir disoproxil fumarate (TDF) has been anecdotally associated with isolated hypophosphatemia (HP) as well as proximal tubular toxicity and renal dysfunction in which HP has consistently been a feature." | 7.73 | Serum hypophosphatemia in tenofovir disoproxil fumarate recipients is multifactorial in origin, questioning the utility of its monitoring in clinical practice. ( Bannister, A; Day, SL; Fisher, M; Hankins, M; Leake Date, HA, 2005) |
"We report two cases in which osteomalacia developed in patients on tenofovir-containing highly active antiretroviral therapy (HAART) in the context of Fanconi syndrome with hypophosphataemia." | 7.73 | The development of hypophosphataemic osteomalacia with myopathy in two patients with HIV infection receiving tenofovir therapy. ( Issa, BG; Parsonage, MJ; Savage, MW; Snowden, N; Wilkins, EG, 2005) |
"Fanconi syndrome with osteomalacia can develop in patients with chronic hepatitis B infection being treated with adefovir at a conventional low dosage of 10 mg/day." | 5.56 | Osteomalacia and renal failure due to Fanconi syndrome caused by long-term low-dose Adefovir Dipivoxil: a case report. ( Cen, X; Cui, Y; Liu, Z; Mu, G; Xiang, Q; Xie, Q; Yu, Y; Zhang, H; Zhang, J, 2020) |
"This case indicates that Fanconi's syndrome with osteomalacia can be acquired by a chronic hepatitis B patient taking ADV at a conventional dosage of 10 mg/day." | 5.42 | Osteomalacia and Fanconi's syndrome caused by long-term low-dose adefovir dipivoxil. ( Chen, YS; Sun, FR; Wang, BF; Wang, BY; Wang, Y; Zhang, D, 2015) |
"Hypophosphatemic osteomalacia and renal Fanconi syndrome can be associated with low-dose ADV." | 5.39 | Hypophosphatemic osteomalacia and renal Fanconi syndrome induced by low-dose adefovir dipivoxil: a case report and literature review suggesting ethnic predisposition. ( Dai, Z; Gu, X; Qian, Y; Wang, L; Wu, C; Zhang, H, 2013) |
"We present a case in wich acute renal failure and proximal tubular dysfunction developed after therapy with tenofovir in a patiente with HIV who had suffered from complications of didanosine treatment." | 5.33 | [Acute renal failure and proximal renal tubular dysfuntion in a patient with acquired immunodeficiency syndrome treated with tenofovir]. ( de la Prada, FJ; Morey, A; Prados, AM; Saus, C; Tugores, A; Uriol, M, 2006) |
" He had been receiving low-dose adefovir dipivoxil (ADV) for the treatment of lamivudine-resistant chronic hepatitis B virus infection for eight years and subsequently developed severe hypophosphatemia and proximal renal tubule dysfunction." | 4.90 | Hypophosphatemic osteomalacia due to drug-induced Fanconi's syndrome associated with adefovir dipivoxil treatment for hepatitis B. ( Eguchi, H; Hiromatsu, Y; Kuwahara, R; Tani, J; Tsuruta, M, 2014) |
"This report suggests the possibility of severe tenofovir-induced nephrotoxicity with combined acute kidney injury, Fanconi syndrome, and nephrogenic diabetes insipidus in the absence of other provoking factors such as use with protease inhibitors or advanced HIV disease, chronic kidney disease, and age." | 4.31 | Fanconi syndrome, diabetes insipidus, and acute kidney injury due to tenofovir disoproxil fumarate: A case report. ( Gill, S; Kalinoski, T; Mehboob, G; Mpejane, O; Zilwa, N, 2023) |
" He had been receiving adefovir dipivoxil (ADV) for the treatment of entecavir (ETV)-resistant chronic hepatitis B (CHB) for four years in his 8-year treatment of hepatocellular carcinoma (HCC), but was referred to our hospital after increased levels of bone pain in his ribs, knees, and ankles." | 3.91 | [Adefovir Dipivoxil-induced Fanconi's Syndrome and Osteomalacia Following Multiple Bone Fractures in a Patient with Chronic Hepatitis B]. ( Ikeda, A; Ikeda, F; Kanzaki, H; Kitamura, Y; Makita, T; Murakawa, K; Nishihara, S; Okada, H; Onishi, H; Sendo, T; Shiraha, H; Takaki, A; Takeuchi, Y; Tanaka, Y; Wada, N; Yasunaka, T, 2019) |
"Adefovir dipivoxil (ADV) is one of the most important nucleostide analogues currently in use for the treatment of chronic hepatitis B virus (HBV) infection." | 3.91 | Low-dose adefovir dipivoxil-induced hypophosphatemia osteomalacia in five chronic hepatitis B virus-infected patients. Is low-dose adefovir dipivoxil-induced nephrotoxicity completely reversible? ( Dai, ZJ; Jin, J; Pan, YJ; Qian, YY; Ruan, LY; Shi, MT; Wu, CM; Zhu, YX, 2019) |
"Adefovir dipivoxil is a nucleotide analogue that is approved for treatment of chronic hepatitis B." | 3.91 | Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir-induced Fanconi syndrome: a case report. ( Aso, Y; Iijima, T; Jojima, T; Kase, M; Kogai, T; Kunii, T; Sakurai, S; Shimizu, M; Usui, I, 2019) |
" The patient had been treated with lamivudine (LAM) in 2005, LAM+adefovir (ADV) in 2009, and ADV+entecavir in 2015 for chronic hepatitis B (CH-B)." | 3.91 | [Marked improvement in renal tubular markers after switching from adefovir to tenofovir alafenamide in a case of Fanconi syndrome diagnosed through high ALP levels]. ( Hiraoka, A; Izumoto, H; Kitahata, S; Kondoh, K; Michitaka, K; Ninomiya, T; Tsubouchi, E; Ueki, H; Yamago, H, 2019) |
" She had a 7-year history of taking adefovir at 10 mg/day for chronic hepatitis B." | 3.88 | Adefovir-induced Fanconi syndrome associated with osteomalacia. ( Cha, SK; Cho, DH; Kim, HS; Kim, JH; Kim, WI; Kim, YJ; Lee, EY; Lee, JH; Lee, SM; Park, KS; Park, S, 2018) |
"An increasing number of case reports suggest that acquired renal Fanconi syndrome may be associated with prolonged use of adefovir against hepatitis B virus." | 3.85 | Nephrolithiasis and Osteomalacia associated with adefovir-induced Fanconi syndrome in a patient with hepatitis B. ( Lin, J; Zhang, D; Zhuo, Y, 2017) |
" He had been receiving low-dose adefovir dipivoxil (ADV, 10 mg/day) for the treatment of chronic hepatitis B virus infection for 7 years and he subsequently developed severe hypophosphatemia and proximal renal tubule dysfunction." | 3.83 | Pathologic Femoral Neck Fracture Due to Fanconi Syndrome Induced by Adefovir Dipivoxil Therapy for Hepatitis B. ( Dan, J; Kim, BK; Lee, HJ; Lee, YS, 2016) |
" Of all the patients, 15 were diagnosed as tumor-induced HO, 4 were long-term oral adefovir dipivoxil-related HO, 3 were associated with Fanconi syndrome, 2 were related to hyperparathyroidism, while 2 were Sjogren's syndrome complicated with renal tubular acidosis." | 3.80 | [The clinical characteristics of 26 cases of hypophosphatemia osteomalacia misdiagnosed as spondyloarthritis]. ( Feng, L; Huang, F; Jin, J; Luo, G; Ma, H; Sun, F; Wang, G; Wang, Y; Yang, J; Zhang, J; Zhao, W; Zhao, Z; Zhu, J, 2014) |
" Here, we describe two additional patients with chronic hepatitis B (CHB) who developed a TDF-induced Fanconi syndrome that reverted after TDF withdrawal and had viral replication fully suppressed upon switching to entecavir (ETV)." | 3.80 | Tenofovir-induced Fanconi syndrome in chronic hepatitis B monoinfected patients that reverted after tenofovir withdrawal. ( Brocchieri, A; Castelli, F; Colombo, M; Facchetti, F; Fugazza, A; Lampertico, P; Mangia, G; Spinetti, A; Viganò, M; Zaltron, S, 2014) |
"A 64-year-old woman was prescribed lamivudine and adefovir (ADV) for chronic hepatitis B." | 3.80 | [A case of chronic hepatitis B managed with continued adefovir despite treatment-related Fanconi syndrome and osteomalacia]. ( Asahina, Y; Iizuka, K; Iizuka, Y; Ito, E; Kobayashi, K; Mochizuki, N; Sakai, H; Watanabe, M, 2014) |
"In human immunodeficiency virus (HIV)-infected patients, tenofovir disoproxil fumarate (TDF) may cause hypophosphatemia leading to osteomalacia due to renal phosphate wasting." | 3.80 | Fibroblast growth factor 23 is elevated in tenofovir-related hypophosphatemia. ( Holmes, DT; Jiang, SY; Kendler, DL; Saeedi, R, 2014) |
"Tenofovir disoproxil fumarate (TDF) is increasingly used in patients with chronic hepatitis B (CHB) infection." | 3.79 | Tenofovir-associated Fanconi syndrome in patients with chronic hepatitis B monoinfection. ( Gracey, DM; McKenzie, P; Snelling, P; Strasser, SI, 2013) |
"We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia." | 3.78 | Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report. ( Arishima, Y; Hirotsu, M; Ishidou, Y; Kakoi, H; Kamizono, J; Komiya, S; Nagano, S; Nakamura, S; Saitoh, Y; Setoguchi, T; Tanaka, M; Yokouchi, M, 2012) |
"We present 2 human immunodeficiency virus-infected patients with tenofovir disoproxil fumarate-induced Fanconi syndrome, leading to osteomalacia." | 3.77 | Tenofovir-induced Fanconi syndrome and osteomalacia in two HIV-infected patients: role of intracellular tenofovir diphosphate levels and review of the literature. ( Bronsveld, W; Haverkort, ME; Huitema, AD; Lips, P; Slieker, WA; ter Heine, R; van der Spek, BW, 2011) |
"Adefovir dipivoxil is commonly used for treatment of chronic hepatitis B." | 3.77 | [Adefovir dipivoxil-induced Fanconi syndrome and hypophosphatemic osteomalacia associated with muscular weakness in a patient with chronic hepatitis B]. ( Dong, GF; Li, L; Xie, YS; Zhang, X, 2011) |
"Combination therapy with adefovir dipivoxil (ADV) and lamivudine (LAM) is recommended for patients infected with LAM-refractory hepatitis B virus (HBV)." | 3.76 | Add-on combination therapy with adefovir dipivoxil induces renal impairment in patients with lamivudine-refractory hepatitis B virus. ( Enomoto, M; Habu, D; Imanishi, Y; Iwai, S; Kawada, N; Kobayashi, S; Morikawa, H; Sakaguchi, H; Shiomi, S; Tamori, A, 2010) |
"We report 3 cases of patients with HIV/AIDS in whom Fanconi syndrome and nephrogenic diabetes insipidus developed secondary to use of an antiretroviral regimen containing tenofovir disoproxil fumarate and didanosine." | 3.75 | Proximal tubular dysfunction associated with tenofovir and didanosine causing Fanconi syndrome and diabetes insipidus: a report of 3 cases. ( Alvarez, S; Brumble, LM; Dwyer, JP; Irizarry-Alvarado, JM; Mendez, JC, 2009) |
"To determine the spectrum of clinical manifestations of hypokalemia associated with tenofovir, we reviewed all reports of grades 3/4 hypokalemia received by Gilead Sciences Department of Safety and Public Health." | 3.74 | Causes and consequences of hypokalemia in patients on tenofovir disoproxil fumarate. ( Curtis, S; Rooney, JF; Shepp, DH, 2007) |
"Tenofovir disoproxil fumarate (TDF) has been anecdotally associated with isolated hypophosphatemia (HP) as well as proximal tubular toxicity and renal dysfunction in which HP has consistently been a feature." | 3.73 | Serum hypophosphatemia in tenofovir disoproxil fumarate recipients is multifactorial in origin, questioning the utility of its monitoring in clinical practice. ( Bannister, A; Day, SL; Fisher, M; Hankins, M; Leake Date, HA, 2005) |
"We report two cases in which osteomalacia developed in patients on tenofovir-containing highly active antiretroviral therapy (HAART) in the context of Fanconi syndrome with hypophosphataemia." | 3.73 | The development of hypophosphataemic osteomalacia with myopathy in two patients with HIV infection receiving tenofovir therapy. ( Issa, BG; Parsonage, MJ; Savage, MW; Snowden, N; Wilkins, EG, 2005) |
"Tenofovir-related tubule damage characterized by Fanconi syndrome, renal insufficiency and nephrogenic diabetes insipidus has been reported in the adult HIV-infected population." | 3.73 | Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir. ( Hussain, S; Khayat, A; Rathore, MH; Tolaymat, A, 2006) |
"A total of 33 participants developed proximal renal tubular dysfunction during the trial, all but one in the ADV group." | 2.70 | A randomized placebo-controlled trial of adefovir dipivoxil in advanced HIV infection: the ADHOC trial. ( , 2002) |
"Fanconi syndrome with osteomalacia can develop in patients with chronic hepatitis B infection being treated with adefovir at a conventional low dosage of 10 mg/day." | 1.56 | Osteomalacia and renal failure due to Fanconi syndrome caused by long-term low-dose Adefovir Dipivoxil: a case report. ( Cen, X; Cui, Y; Liu, Z; Mu, G; Xiang, Q; Xie, Q; Yu, Y; Zhang, H; Zhang, J, 2020) |
"He had been diagnosed with diabetic kidney disease and osteomalacia due to vitamin D deficiency; thus, ADV was not discontinued until he was referred to us." | 1.51 | Hypophosphatemic Osteomalacia Associated with Adefovir-induced Fanconi Syndrome Initially Diagnosed as Diabetic Kidney Disease and Vitamin D Deficiency. ( Iino, N; Koda, R; Narita, I; Tsuchida, M, 2019) |
"Acquired Fanconi syndrome has been associated with the long-term ingestion of several nucleoside analogs used to treat chronic hepatitis B virus infection." | 1.51 | A case of entecavir-induced Fanconi syndrome. ( Fujii, T; Kawasoe, K; Nitta, K; Ohta, A, 2019) |
"Fanconi syndrome is a rare adverse effect of tenofovir disoproxil fumarate (TDF)." | 1.46 | Short Communication: Resolution of Tenofovir Disoproxil Fumarate Induced Fanconi Syndrome with Switch to Tenofovir Alafenamide Fumarate in a HIV-1 and Hepatitis B Coinfected Patient. ( Karris, MY, 2017) |
"This case indicates that Fanconi's syndrome with osteomalacia can be acquired by a chronic hepatitis B patient taking ADV at a conventional dosage of 10 mg/day." | 1.42 | Osteomalacia and Fanconi's syndrome caused by long-term low-dose adefovir dipivoxil. ( Chen, YS; Sun, FR; Wang, BF; Wang, BY; Wang, Y; Zhang, D, 2015) |
"The long-term use of tenofovir, a commonly used anti-HIV drug, can result in renal damage." | 1.40 | Mitochondrial dysfunction and electron transport chain complex defect in a rat model of tenofovir disoproxil fumarate nephrotoxicity. ( Abraham, P; Isaac, B; Ramamoorthy, H, 2014) |
"Hypophosphatemic osteomalacia and renal Fanconi syndrome can be associated with low-dose ADV." | 1.39 | Hypophosphatemic osteomalacia and renal Fanconi syndrome induced by low-dose adefovir dipivoxil: a case report and literature review suggesting ethnic predisposition. ( Dai, Z; Gu, X; Qian, Y; Wang, L; Wu, C; Zhang, H, 2013) |
"Adefovir dipivoxil (ADV) is an oral bioavailable prodrug of adefovir that possesses potent in vitro activity against hepadnaviruses, retroviruses and herpes viruses." | 1.38 | Nephrotoxicity, including acquired Fanconi's syndrome, caused by adefovir dipivoxil - is there a safe dose? ( Ho, YY; Law, ST; Li, KK, 2012) |
"Fanconi syndrome is a side effect of tenofovir." | 1.37 | [Renal adverse reactions of antiretroviral medication: proximal tubular dysfunction associated with tenofovir]. ( Kuijper, A; Mudrikova, T; Rookmaker, MB, 2011) |
" A relatively uncommon adverse effect of this drug is Fanconi syndrome." | 1.35 | Tenofovir-associated Fanconi syndrome: review of the FDA adverse event reporting system. ( Gupta, SK, 2008) |
"We present a case in wich acute renal failure and proximal tubular dysfunction developed after therapy with tenofovir in a patiente with HIV who had suffered from complications of didanosine treatment." | 1.33 | [Acute renal failure and proximal renal tubular dysfuntion in a patient with acquired immunodeficiency syndrome treated with tenofovir]. ( de la Prada, FJ; Morey, A; Prados, AM; Saus, C; Tugores, A; Uriol, M, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (0.97) | 18.2507 |
2000's | 37 (35.92) | 29.6817 |
2010's | 60 (58.25) | 24.3611 |
2020's | 5 (4.85) | 2.80 |
Authors | Studies |
---|---|
Zilwa, N | 1 |
Mpejane, O | 1 |
Mehboob, G | 1 |
Gill, S | 1 |
Kalinoski, T | 1 |
Álvarez, H | 1 |
Llibre, JM | 1 |
Bahr, NC | 2 |
Yarlagadda, SG | 2 |
Leungsuwan, S | 1 |
Hooi, B | 1 |
Myint, KS | 1 |
Sun, L | 1 |
Yi, D | 1 |
Sun, W | 1 |
Wang, C | 1 |
Xiang, Q | 1 |
Liu, Z | 1 |
Yu, Y | 1 |
Zhang, H | 2 |
Xie, Q | 1 |
Mu, G | 1 |
Zhang, J | 2 |
Cen, X | 1 |
Cui, Y | 1 |
Song, K | 1 |
Yan, Q | 1 |
Yang, Y | 1 |
Lv, M | 1 |
Chen, Y | 1 |
Dai, Y | 1 |
Zhang, L | 1 |
Huang, Y | 1 |
Zhang, C | 1 |
Gao, H | 1 |
Karris, MY | 1 |
Lin, J | 1 |
Zhuo, Y | 1 |
Zhang, D | 2 |
Park, S | 1 |
Kim, WI | 1 |
Cho, DH | 1 |
Kim, YJ | 1 |
Kim, HS | 1 |
Kim, JH | 1 |
Cha, SK | 1 |
Park, KS | 1 |
Lee, JH | 1 |
Lee, SM | 1 |
Lee, EY | 1 |
Cho, J | 1 |
Cheung, PP | 1 |
Watanabe, K | 1 |
Hashimoto, S | 1 |
Maoka, T | 1 |
Yamamoto, R | 1 |
Okamoto, N | 1 |
Koike, T | 1 |
Koda, R | 1 |
Tsuchida, M | 1 |
Iino, N | 1 |
Narita, I | 1 |
Makita, T | 1 |
Kanzaki, H | 1 |
Onishi, H | 1 |
Ikeda, A | 1 |
Takaki, A | 2 |
Wada, N | 1 |
Takeuchi, Y | 1 |
Yasunaka, T | 1 |
Ikeda, F | 1 |
Shiraha, H | 1 |
Tanaka, Y | 1 |
Nishihara, S | 1 |
Murakawa, K | 1 |
Kitamura, Y | 1 |
Okada, H | 1 |
Sendo, T | 1 |
Kondoh, K | 1 |
Michitaka, K | 1 |
Hiraoka, A | 1 |
Izumoto, H | 1 |
Ueki, H | 1 |
Kitahata, S | 1 |
Yamago, H | 1 |
Tsubouchi, E | 1 |
Ninomiya, T | 1 |
Kunii, T | 1 |
Iijima, T | 1 |
Jojima, T | 1 |
Shimizu, M | 1 |
Kase, M | 1 |
Sakurai, S | 1 |
Kogai, T | 1 |
Usui, I | 1 |
Aso, Y | 1 |
Qian, YY | 1 |
Dai, ZJ | 1 |
Ruan, LY | 1 |
Pan, YJ | 1 |
Jin, J | 2 |
Shi, MT | 1 |
Zhu, YX | 1 |
Wu, CM | 1 |
Fujii, T | 1 |
Kawasoe, K | 1 |
Ohta, A | 1 |
Nitta, K | 1 |
Wu, C | 1 |
Qian, Y | 1 |
Wang, L | 1 |
Gu, X | 1 |
Dai, Z | 1 |
Gracey, DM | 2 |
Snelling, P | 1 |
McKenzie, P | 1 |
Strasser, SI | 1 |
Lucey, JM | 1 |
Hsu, P | 1 |
Ziegler, JB | 1 |
Bickel, M | 1 |
Khaykin, P | 1 |
Stephan, C | 1 |
Schmidt, K | 1 |
Buettner, M | 1 |
Amann, K | 1 |
Lutz, T | 1 |
Gute, P | 1 |
Haberl, A | 1 |
Geiger, H | 1 |
Brodt, HR | 1 |
Jung, O | 1 |
Eguchi, H | 1 |
Tsuruta, M | 1 |
Tani, J | 1 |
Kuwahara, R | 1 |
Hiromatsu, Y | 1 |
Hamnvik, OP | 2 |
Vaidya, A | 1 |
Becker, C | 1 |
Terasaka, T | 1 |
Ueta, E | 1 |
Ebara, H | 1 |
Waseda, K | 1 |
Hanayama, Y | 1 |
Kawabata, T | 1 |
Sugiyama, H | 1 |
Hidani, K | 1 |
Otsuka, F | 1 |
Becker, CB | 1 |
Levy, BD | 1 |
Loscalzo, J | 1 |
Ramamoorthy, H | 1 |
Abraham, P | 2 |
Isaac, B | 1 |
Zhu, LN | 1 |
Mou, LJ | 1 |
Hu, Y | 1 |
Chen, JX | 1 |
Gupta, SK | 3 |
Anderson, AM | 1 |
Ebrahimi, R | 1 |
Fralich, T | 1 |
Graham, H | 1 |
Scharen-Guivel, V | 2 |
Flaherty, JF | 1 |
Fortin, C | 1 |
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Yu, W | 1 |
Xia, WB | 1 |
Zhu, H | 1 |
Yuan, X | 1 |
Tang, L | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Severe Impairment of Solute-Free Water Clearance in Patients With HIV Infection[NCT01869010] | 30 participants (Actual) | Observational | 2010-01-31 | Completed | |||
Effects of Sofosbuvir/Ledipasvir Treatment on the Pharmacokinetics and Renal Safety of Tenofovir[NCT02588287] | 14 participants (Actual) | Interventional | 2015-11-30 | Completed | |||
Effects of Ledipasvir/Sofosbuvir Treatment on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF) in Patients With HIV.[NCT03126370] | Phase 4 | 10 participants (Actual) | Interventional | 2018-01-08 | Completed | ||
Impact of Drug Therapy and Co-Morbidities on the Development of Renal Impairment in HIV-Infected Patients[NCT00551655] | 684 participants (Actual) | Observational | 2007-05-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Compare plasma tenofovir AUC0-24 between TAF with boosted PI vs. TDF with boosted PI (Phase 2 vs. 1), and between TAF with boosted PI and LDV/SOF vs. TDF with boosted PI (Phase 3 vs. 1) (NCT03126370)
Timeframe: 12 weeks and 24 weeks and 28 weeks
Intervention | ng*h/mL (Geometric Mean) |
---|---|
TDF With a Boosted PI | 3466 |
TAF With a Boosted PI | 743 |
TAF With a Boosted PI and LDV/SOF | 868 |
Compare tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) between TAF with a boosted PI vs. TDF with a boosted PI (Phase 2 vs. 1), and TAF with a boosted PI and LDV/SOF vs. TDF with a boosted PI (Phase 3 vs. 1) (NCT03126370)
Timeframe: 12 weeks and 24 and 28 weeks
Intervention | fmol/2x7mm punches (Geometric Mean) |
---|---|
TDF With a Boosted PI | 36014 |
TAF With a Boosted PI | 6735 |
TAF With a Boosted PI and LDV/SOF | 6100 |
Compare tenofovir-diphosphate (TFV-DP) in peripheral blood mononuclear cells (PBMCs) between TAF with a boosted PI vs. TDF with a boosted PI (Phase 2 vs. 1), and TAF with a boosted PI and LDV/SOF vs. TDF with a boosted PI (Phase 3 vs. 1). (NCT03126370)
Timeframe: 12 weeks, and 24 weeks and 28 weeks
Intervention | fmol/10^6 cells (Geometric Mean) |
---|---|
TDF With a Boosted PI | 83.0 |
TAF With a Boosted PI | 926 |
TAF With a Boosted PI and LDV/SOF | 1129 |
Change in estimated glomerular filtration rate (eGFR) (NCT03126370)
Timeframe: 12 weeks, 24 weeks, and 28 weeks
Intervention | mL/min/1.73 m^2 (Geometric Mean) |
---|---|
TDF With a Boosted PI | 86.7 |
TAF With a Boosted PI | 91.0 |
TAF With a Boosted PI and LDV/SOF | 88.1 |
Change in estimated glomerular filtration rate (eGFR) and renal biomarkers: Urine protein to creatinine ratio (UPCR) (NCT03126370)
Timeframe: 12 weeks, 24 weeks, and 28 weeks
Intervention | mg/g (Geometric Mean) |
---|---|
TDF With a Boosted PI | 134 |
TAF With a Boosted PI | 118 |
TAF With a Boosted PI and LDV/SOF | 97.3 |
Change in renal biomarkers: urinary beta-2 microglobulin (B2M)/creatinine (Cr) ratio, and urinary retinol binding protein (RBP)/Cr ratio (NCT03126370)
Timeframe: 12 weeks, 24 weeks, and 28 weeks
Intervention | ug/g (Geometric Mean) | |
---|---|---|
β2M:Cr ratio | RBP:Cr ratio | |
TAF With a Boosted PI | 224 | 242 |
TAF With a Boosted PI and LDV/SOF | 178 | 146 |
TDF With a Boosted PI | 419 | 436 |
10 reviews available for adenine and Adult Fanconi Syndrome
Article | Year |
---|---|
Fanconi syndrome induced by adefovir dipivoxil: a case report and clinical review.
Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organo | 2020 |
Hypophosphatemic osteomalacia due to drug-induced Fanconi's syndrome associated with adefovir dipivoxil treatment for hepatitis B.
Topics: Adenine; Bone Diseases, Metabolic; Fanconi Syndrome; Hepatitis B, Chronic; Humans; Hypophosphatemia; | 2014 |
Tenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus.
Topics: Adenine; Alanine; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; Dru | 2016 |
Tenofovir-associated kidney toxicity in HIV-infected patients: a review of the evidence.
Topics: Adenine; Animals; Fanconi Syndrome; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Disea | 2011 |
Tenofovir-associated kidney toxicity in HIV-infected patients: a review of the evidence.
Topics: Adenine; Animals; Fanconi Syndrome; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Disea | 2011 |
Tenofovir-associated kidney toxicity in HIV-infected patients: a review of the evidence.
Topics: Adenine; Animals; Fanconi Syndrome; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Disea | 2011 |
Tenofovir-associated kidney toxicity in HIV-infected patients: a review of the evidence.
Topics: Adenine; Animals; Fanconi Syndrome; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Disea | 2011 |
The use of biomarkers for assessing HAART-associated renal toxicity in HIV-infected patients.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiretroviral Therapy, Highly Active; Biomarkers; Crea | 2012 |
Tenofovir-related nephrotoxicity: case report and review of the literature.
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adenine; Anti-HIV Agents; Clinical Chemistr | 2004 |
Fanconi's syndrome in HIV+ adults: report of three cases and literature review.
Topics: Adenine; Adult; Anti-Retroviral Agents; Bone Density; Calcitriol; Calcium; Fanconi Syndrome; Female; | 2004 |
Acute renal failure and Fanconi syndrome in an AIDS patient on tenofovir treatment--case report and review of literature.
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adenine; Anti-HIV Agents; Creatinine; Fanco | 2005 |
Editorial comment: tenofovir nephrotoxicity--vigilance required.
Topics: Adenine; Fanconi Syndrome; Glycosuria; HIV Infections; Humans; Hypokalemia; Hypophosphatemia; Organo | 2005 |
Fanconi syndrome associated with use of tenofovir in HIV-infected patients: a case report and review of the literature.
Topics: Adenine; Fanconi Syndrome; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Reverse Tr | 2005 |
1 trial available for adenine and Adult Fanconi Syndrome
Article | Year |
---|---|
A randomized placebo-controlled trial of adefovir dipivoxil in advanced HIV infection: the ADHOC trial.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Antiviral Agents; Body Weight; CD4 Lymphocyte Count; Do | 2002 |
92 other studies available for adenine and Adult Fanconi Syndrome
Article | Year |
---|---|
Fanconi syndrome, diabetes insipidus, and acute kidney injury due to tenofovir disoproxil fumarate: A case report.
Topics: Acute Kidney Injury; Adenine; Anti-HIV Agents; Diabetes Insipidus; Diabetes Mellitus; Fanconi Syndro | 2023 |
Fanconi Syndrome and Tenofovir Alafenamide.
Topics: Adenine; Alanine; Anti-HIV Agents; Fanconi Syndrome; Humans; Tenofovir | 2019 |
Fanconi Syndrome and Tenofovir Alafenamide.
Topics: Adenine; Alanine; Anti-HIV Agents; Fanconi Syndrome; Humans; Tenofovir | 2019 |
Hypophosphatemic Osteomalacia Due to Adefovir-Induced Fanconi Syndrome.
Topics: Adenine; Aged; Alanine; Antiviral Agents; Fanconi Syndrome; Female; Hepatitis C, Chronic; Humans; Hy | 2020 |
Retrospective analysis of the clinical characteristics of adefovir dipivoxil-induced Fanconi's syndrome in the Chinese population.
Topics: Adenine; Adult; Aged; Alkaline Phosphatase; Asian People; Bone Density; Fanconi Syndrome; Female; Gl | 2020 |
Osteomalacia and renal failure due to Fanconi syndrome caused by long-term low-dose Adefovir Dipivoxil: a case report.
Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organo | 2020 |
Short Communication: Resolution of Tenofovir Disoproxil Fumarate Induced Fanconi Syndrome with Switch to Tenofovir Alafenamide Fumarate in a HIV-1 and Hepatitis B Coinfected Patient.
Topics: Adenine; Alanine; Anti-HIV Agents; Coinfection; Fanconi Syndrome; Hepatitis B, Chronic; HIV Infectio | 2017 |
Nephrolithiasis and Osteomalacia associated with adefovir-induced Fanconi syndrome in a patient with hepatitis B.
Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Hepatitis B; Humans; Male; Middle Aged; Nephrolithiasis | 2017 |
Adefovir-induced Fanconi syndrome associated with osteomalacia.
Topics: Adenine; Adult; Bone and Bones; Fanconi Syndrome; Female; Fibroblast Growth Factor-23; Fibroblast Gr | 2018 |
Osteomalacia Due to Drug-Induced Fanconi Syndrome.
Topics: Adenine; Aged; Antiviral Agents; Fanconi Syndrome; Hepatitis B; Humans; Male; Organophosphonates; Os | 2018 |
[A Case of Fanconi's Syndrome Induced by Adefovir in Hepatitis Type B Patient].
Topics: Adenine; Aged; Antiviral Agents; Fanconi Syndrome; Female; Guanine; Hepatitis B, Chronic; Humans; Or | 2016 |
Hypophosphatemic Osteomalacia Associated with Adefovir-induced Fanconi Syndrome Initially Diagnosed as Diabetic Kidney Disease and Vitamin D Deficiency.
Topics: Adenine; Aged; Antiviral Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diagnostic Error | 2019 |
Fanconi Syndrome and Tenofovir Alafenamide: A Case Report.
Topics: Adenine; Alanine; Antiviral Agents; Fanconi Syndrome; HIV Infections; Humans; Male; Middle Aged; Ten | 2019 |
[Adefovir Dipivoxil-induced Fanconi's Syndrome and Osteomalacia Following Multiple Bone Fractures in a Patient with Chronic Hepatitis B].
Topics: Adenine; Aged; Carcinoma, Hepatocellular; Fanconi Syndrome; Fractures, Bone; Hepatitis B, Chronic; H | 2019 |
[Marked improvement in renal tubular markers after switching from adefovir to tenofovir alafenamide in a case of Fanconi syndrome diagnosed through high ALP levels].
Topics: Adenine; Alanine; Alkaline Phosphatase; Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, V | 2019 |
Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir-induced Fanconi syndrome: a case report.
Topics: Adenine; Adult; Antiviral Agents; Bone Density Conservation Agents; Denosumab; Fanconi Syndrome; Hep | 2019 |
Low-dose adefovir dipivoxil-induced hypophosphatemia osteomalacia in five chronic hepatitis B virus-infected patients. Is low-dose adefovir dipivoxil-induced nephrotoxicity completely reversible?
Topics: Adenine; Aged; Dose-Response Relationship, Drug; Fanconi Syndrome; Female; Hepatitis B, Chronic; Hum | 2019 |
A case of entecavir-induced Fanconi syndrome.
Topics: Acidosis; Acute Kidney Injury; Adenine; Aged; Alanine; Antiviral Agents; Fanconi Syndrome; Guanine; | 2019 |
Hypophosphatemic osteomalacia and renal Fanconi syndrome induced by low-dose adefovir dipivoxil: a case report and literature review suggesting ethnic predisposition.
Topics: Adenine; Antiviral Agents; Dose-Response Relationship, Drug; Fanconi Syndrome; Humans; Hypophosphate | 2013 |
Tenofovir-associated Fanconi syndrome in patients with chronic hepatitis B monoinfection.
Topics: Adenine; Adult; Antiviral Agents; Biopsy; Creatinine; Fanconi Syndrome; Hepatitis B, Chronic; Humans | 2013 |
Tenofovir-related Fanconi's syndrome and osteomalacia in a teenager with HIV.
Topics: Adenine; Adolescent; Anti-HIV Agents; Fanconi Syndrome; HIV Infections; Humans; Male; Organophosphon | 2013 |
Acute kidney injury caused by tenofovir disoproxil fumarate and diclofenac co-administration.
Topics: Acute Kidney Injury; Adenine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Inter | 2013 |
Interactive medical case: wasting away.
Topics: Adenine; Adult; Bone Density; Electrolytes; Fanconi Syndrome; Female; Hepatitis B, Chronic; Humans; | 2014 |
Long-term observation of osteomalacia caused by adefovir-induced Fanconi's syndrome.
Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Humans; Male; Middle Aged; Organophosphonates; Osteomal | 2014 |
Clinical problem-solving. Wasting away.
Topics: Adenine; Adult; Bone Diseases, Metabolic; Cachexia; Diagnosis, Differential; Fanconi Syndrome; Femal | 2014 |
Mitochondrial dysfunction and electron transport chain complex defect in a rat model of tenofovir disoproxil fumarate nephrotoxicity.
Topics: Adenine; Animals; Anti-HIV Agents; Electron Transport Chain Complex Proteins; Fanconi Syndrome; Kidn | 2014 |
Fanconi syndrome caused by low-dose adefovir dipivoxil.
Topics: Adenine; Dose-Response Relationship, Drug; Fanconi Syndrome; Female; Humans; Middle Aged; Organophos | 2014 |
Fanconi syndrome accompanied by renal function decline with tenofovir disoproxil fumarate: a prospective, case-control study of predictors and resolution in HIV-infected patients.
Topics: Adenine; Adult; Anti-HIV Agents; Case-Control Studies; Creatinine; Fanconi Syndrome; Female; Glomeru | 2014 |
Fibroblast growth factor 23 is elevated in tenofovir-related hypophosphatemia.
Topics: Adenine; Adult; Anti-HIV Agents; Bone Density; Fanconi Syndrome; Fibroblast Growth Factor-23; Fibrob | 2014 |
[A case of chronic hepatitis B managed with continued adefovir despite treatment-related Fanconi syndrome and osteomalacia].
Topics: Adenine; Fanconi Syndrome; Female; Hepatitis B, Chronic; Humans; Middle Aged; Organophosphonates; Os | 2014 |
Tenofovir-associated Fanconi syndrome in a patient with chronic hepatitis B.
Topics: Adenine; Aged, 80 and over; Antiviral Agents; Fanconi Syndrome; Fatal Outcome; Hepatitis B, Chronic; | 2014 |
Tenofovir-induced Fanconi syndrome in chronic hepatitis B monoinfected patients that reverted after tenofovir withdrawal.
Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Human | 2014 |
A pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome.
Topics: Adenine; Alleles; Anti-HIV Agents; Biomarkers, Pharmacological; Case-Control Studies; Fanconi Syndro | 2015 |
[Hypophosphatemic osteomalacia and renal Fanconi syndrome induced by adefovir in a patient with chronic hepatitis B].
Topics: Adenine; Fanconi Syndrome; Hepatitis B, Chronic; Humans; Hypophosphatemia; Organophosphonates; Osteo | 2014 |
[The clinical characteristics of 26 cases of hypophosphatemia osteomalacia misdiagnosed as spondyloarthritis].
Topics: Adenine; Adult; Antirheumatic Agents; Biomarkers; C-Reactive Protein; Fanconi Syndrome; Female; Huma | 2014 |
[Case report; A case of Fanconi's syndrome with pathological ulnar fractures improved by dose reduction of adefovir and supplementation of oral phosphate].
Topics: Adenine; Administration, Oral; Aged; Antiviral Agents; Fanconi Syndrome; Female; Fractures, Spontane | 2014 |
Osteomalacia and Fanconi's syndrome caused by long-term low-dose adefovir dipivoxil.
Topics: Adenine; Antiviral Agents; Calcium; Dose-Response Relationship, Drug; Drug Monitoring; Fanconi Syndr | 2015 |
Low-dose adefovir dipivoxil may induce Fanconi syndrome: clinical characteristics and long-term follow-up for Chinese patients.
Topics: Adenine; Adult; Alkaline Phosphatase; Antiviral Agents; Asian People; Bone Density; Creatinine; Drug | 2015 |
[Clinical analysis of Fanconi syndrome induced by adefovir dipivoxil].
Topics: Adenine; Fanconi Syndrome; Humans; Organophosphonates | 2015 |
First case report of renal improvement on tenofovir alafenamide in an HIV/hepatitis B virus-coinfected patient with adefovir-induced Fanconi's syndrome.
Topics: Absorptiometry, Photon; Adenine; Alanine; Coinfection; Dose-Response Relationship, Drug; Fanconi Syn | 2016 |
Pathologic Femoral Neck Fracture Due to Fanconi Syndrome Induced by Adefovir Dipivoxil Therapy for Hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Fanconi Syndrome; Femoral Neck Fractures; Fractures, Spontaneous; | 2016 |
Urinary cystatin C can improve the renal safety follow-up of tenofovir-treated patients.
Topics: Adenine; Anti-HIV Agents; Biomarkers; Creatinine; Cystatin C; Fanconi Syndrome; HIV Infections; Huma | 2009 |
Adefovir dipivoxil-induced acute tubular necrosis and Fanconi syndrome in a renal transplant patient.
Topics: Acute Kidney Injury; Adenine; Antiviral Agents; Fanconi Syndrome; Hepatitis B, Chronic; Humans; Kidn | 2009 |
Kidney tubular abnormalities in the absence of impaired glomerular function in HIV patients treated with tenofovir.
Topics: Adenine; Adult; Age Factors; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Creatinine; Epi | 2009 |
Bone pain due to fractures revealing osteomalacia related to tenofovir-induced proximal renal tubular dysfunction in a human immunodeficiency virus-infected patient.
Topics: Adenine; Bone Density Conservation Agents; Fanconi Syndrome; Female; Fractures, Bone; HIV Infections | 2009 |
Proximal tubular dysfunction associated with tenofovir and didanosine causing Fanconi syndrome and diabetes insipidus: a report of 3 cases.
Topics: Adenine; Adult; Anti-HIV Agents; Diabetes Insipidus; Didanosine; Drug Therapy, Combination; Fanconi | 2009 |
Editorial comment: tenofovir nephrotoxicity--the disconnect between clinical trials and real-world practice.
Topics: Adenine; Anti-HIV Agents; Clinical Trials as Topic; Diabetes Insipidus; Didanosine; Drug Therapy, Co | 2009 |
Tenofovir-associated renal and bone toxicity.
Topics: Adenine; Adult; Anti-HIV Agents; Creatinine; Fanconi Syndrome; Female; Glycosuria; HIV Infections; H | 2009 |
Tenofovir-related acute kidney injury and proximal tubule dysfunction precipitated by diclofenac: a case of drug-drug interaction.
Topics: Acute Kidney Injury; Adenine; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Diag | 2009 |
Add-on combination therapy with adefovir dipivoxil induces renal impairment in patients with lamivudine-refractory hepatitis B virus.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; Creatinine; DNA, Viral; Drug Resistanc | 2010 |
Impact of tenofovir on renal function in HIV-infected, antiretroviral-naive patients.
Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Creatinine; Fanconi Syndrome; | 2010 |
Incidence of proximal renal tubular dysfunction in patients on tenofovir disoproxil fumarate.
Topics: Adenine; Anti-HIV Agents; Fanconi Syndrome; HIV Infections; Humans; Incidence; Organophosphonates; R | 2010 |
[Fanconi syndrome associated with tenofovir treatment: a presentation of two cases].
Topics: Adenine; Adult; Fanconi Syndrome; Humans; Male; Middle Aged; Organophosphonates; Reverse Transcripta | 2010 |
Tenofovir/probenecid combination in HIV/HBV-coinfected patients: how to escape Fanconi syndrome recurrence?
Topics: Adenine; Fanconi Syndrome; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Organophosphon | 2010 |
[Two cases of Fanconi's syndrome induced by tenofovir in the Ivory Coast].
Topics: Adenine; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cote d | 2011 |
[HIV infected women with intense bone and muscular pain and general weakness].
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Therapy, Combina | 2011 |
[Renal adverse reactions of antiretroviral medication: proximal tubular dysfunction associated with tenofovir].
Topics: Adenine; Anti-HIV Agents; Fanconi Syndrome; HIV Infections; Humans; Male; Middle Aged; Organophospho | 2011 |
Hypophosphatemic osteomalacia as a long-term complication after liver transplantation.
Topics: Adenine; Aged; Fanconi Syndrome; Female; Humans; Hypophosphatemia; Immunosuppressive Agents; Liver T | 2011 |
Increased risk of abnormal proximal renal tubular function with HIV infection and antiretroviral therapy.
Topics: Adenine; Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; C | 2011 |
Tenofovir-induced Fanconi syndrome and osteomalacia in two HIV-infected patients: role of intracellular tenofovir diphosphate levels and review of the literature.
Topics: Adenine; Adult; Anti-HIV Agents; Diphosphates; Fanconi Syndrome; HIV Infections; Humans; Male; Middl | 2011 |
Nephrotoxicity, including acquired Fanconi's syndrome, caused by adefovir dipivoxil - is there a safe dose?
Topics: Adenine; Aged; Antiviral Agents; Dose-Response Relationship, Drug; Fanconi Syndrome; Female; Hepatit | 2012 |
Bilateral pathologic hip fractures associated with antiretroviral therapy: a case report.
Topics: Accidental Falls; Adenine; Alendronate; Anti-HIV Agents; Bone Density Conservation Agents; Comorbidi | 2011 |
Fanconi syndrome-like tubular acidosis associated with a tenofovir-containing antiretroviral regimen in a human immunodeficiency virus-1-infected Asian woman.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Drug Therapy, Combin | 2012 |
[Adefovir dipivoxil-induced Fanconi syndrome and hypophosphatemic osteomalacia associated with muscular weakness in a patient with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Bone Diseases, Metabolic; Fanconi Syndrome; Hepatitis B, Chronic; Humans; | 2011 |
An unrecognised case of tenofovir-associated Fanconi syndrome.
Topics: Adenine; Adolescent; Anti-HIV Agents; Fanconi Syndrome; HIV Infections; Humans; Male; Organophosphon | 2012 |
Prolonged adefovir therapy associated Fanconi syndrome and interstitial nephritis in hepatitis B.
Topics: Adenine; Drug Administration Schedule; Fanconi Syndrome; Hepatitis B; Humans; Male; Middle Aged; Nep | 2012 |
Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report.
Topics: Adenine; Antiviral Agents; Arthroplasty, Replacement, Hip; Fanconi Syndrome; Femoral Neck Fractures; | 2012 |
Osteomalacia due to Fanconi's syndrome and renal failure caused by long-term low-dose adefovir dipivoxil.
Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organo | 2013 |
Fanconi syndrome and renal failure induced by tenofovir: a first case report.
Topics: Adenine; Anti-HIV Agents; Fanconi Syndrome; Female; HIV Seropositivity; Humans; Middle Aged; Organop | 2002 |
Renal lesions in HIV-1-positive patient treated with tenofovir.
Topics: Acute Kidney Injury; Adenine; Anti-HIV Agents; Fanconi Syndrome; HIV Infections; HIV-1; Humans; Male | 2003 |
Tenofovir-related nephrotoxicity in human immunodeficiency virus-infected patients: three cases of renal failure, Fanconi syndrome, and nephrogenic diabetes insipidus.
Topics: Acidosis; Adenine; Adult; Anti-HIV Agents; Creatinine; Diabetes Insipidus, Nephrogenic; Drug Monitor | 2003 |
Fanconi-like syndrome and rhabdomyolysis in a person with HIV infection on highly active antiretroviral treatment including tenofovir.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Fanconi Syndrome; Female; HIV Serop | 2003 |
Tenofovir-related Fanconi syndrome with nephrogenic diabetes insipidus in a patient with acquired immunodeficiency syndrome: the role of lopinavir-ritonavir-didanosine.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Diabetes Insipidus, Nephrogenic | 2003 |
Fanconi syndrome and acute renal failure in a patient treated with tenofovir: a call for caution.
Topics: Acute Kidney Injury; Adenine; Adult; Anti-HIV Agents; Fanconi Syndrome; HIV Seropositivity; HIV-1; H | 2004 |
Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy)propyl]adenine (tenofovir) to newborn and infant rhesus macaques.
Topics: Absorptiometry, Photon; Adenine; Animals; Animals, Newborn; Anti-HIV Agents; Area Under Curve; Blood | 2004 |
Tubulopathy consecutive to tenofovir-containing antiretroviral therapy in two patients infected with human immunodeficiency virus-1.
Topics: Adenine; Anti-HIV Agents; Drug Therapy, Combination; Fanconi Syndrome; HIV Infections; HIV-1; Humans | 2004 |
Tenofovir-associated nephrotoxicity: Fanconi syndrome and renal failure.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Fanconi Syndrome; Humans; Kidne | 2004 |
Serum hypophosphatemia in tenofovir disoproxil fumarate recipients is multifactorial in origin, questioning the utility of its monitoring in clinical practice.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood Chemical Analysis; Creatinine | 2005 |
[Acute renal failure, Fanconi syndrome and insipidus diabetes in a HIV-infected patient treated with Tenofovir].
Topics: Acute Kidney Injury; Adenine; Adult; Diabetes Insipidus; Fanconi Syndrome; HIV Infections; Humans; M | 2005 |
Tenofovir-induced renal tubular dysfunction presenting with hypocalcaemia.
Topics: Adenine; Anti-HIV Agents; Bone Density Conservation Agents; Fanconi Syndrome; HIV Infections; Humans | 2006 |
The development of hypophosphataemic osteomalacia with myopathy in two patients with HIV infection receiving tenofovir therapy.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Fanconi Syndrome; Female; HIV Infec | 2005 |
Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir.
Topics: Adenine; Anti-HIV Agents; Child; Diabetes Insipidus, Nephrogenic; Didanosine; Drug Therapy, Combinat | 2006 |
Estimating renal function in patients on tenofovir disoproxil fumarate: suggestions for safer use.
Topics: Adenine; Creatinine; Dose-Response Relationship, Drug; Fanconi Syndrome; Glomerular Filtration Rate; | 2006 |
Acquired Fanconi's syndrome associated with tenofovir therapy.
Topics: Adenine; Adult; Fanconi Syndrome; Humans; Male; Organophosphonates; Tenofovir | 2006 |
Toward a pharmacogenetic understanding of nucleotide and nucleoside analogue toxicity.
Topics: Adenine; Anti-HIV Agents; Fanconi Syndrome; Haplotypes; HIV Infections; Humans; Membrane Transport P | 2006 |
Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Case-Control Studies; Fanconi Syndrome; Female; Gene Frequenc | 2006 |
[Acute renal failure and proximal renal tubular dysfuntion in a patient with acquired immunodeficiency syndrome treated with tenofovir].
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adenine; Aged; Anti-HIV Agents; Fanconi Syn | 2006 |
Causes and consequences of hypokalemia in patients on tenofovir disoproxil fumarate.
Topics: Adenine; Adult; Cause of Death; Drug Monitoring; Drug Synergism; Fanconi Syndrome; Female; Guideline | 2007 |
Bone disease and pathologic fractures in a patient with tenofovir-induced Fanconi syndrome.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Diseases; Fanconi Syndrome; Fe | 2007 |
Editorial comment: Fanconi syndrome and tenofovir--understanding proximal tubular function.
Topics: Adenine; Adult; Anti-HIV Agents; Child; Fanconi Syndrome; Humans; Kidney Tubules, Proximal; Organoph | 2007 |
Tenofovir-associated Fanconi syndrome: review of the FDA adverse event reporting system.
Topics: Adenine; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Anti-HIV Agents; Child; F | 2008 |
Kidney dysfunction: a safety update on adefovir (preveon).
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Creatinine; Fanconi Syndrome; HIV Infections; Humans; Hy | 1998 |