adenine has been researched along with Adenomatous Polyposis Coli in 9 studies
Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A mouse model of human Familial Adenomatous Polyposis responds favorably to pharmacological inhibition of 5'-methylthioadenosine phosphorylase (MTAP)." | 1.62 | Transition state analogue of MTAP extends lifespan of APC ( Augenlicht, LH; Basu, I; Feng, M; Firestone, RS; Peregrina, K; Schramm, VL, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Firestone, RS | 1 |
| Feng, M | 1 |
| Basu, I | 1 |
| Peregrina, K | 1 |
| Augenlicht, LH | 1 |
| Schramm, VL | 1 |
| Nakamura, T | 1 |
| Okabe, K | 1 |
| Hirayama, S | 1 |
| Chirifu, M | 1 |
| Ikemizu, S | 1 |
| Morioka, H | 1 |
| Nakabeppu, Y | 1 |
| Yamagata, Y | 1 |
| Nelson, SR | 1 |
| Kathe, SD | 1 |
| Hilzinger, TS | 1 |
| Averill, AM | 1 |
| Warshaw, DM | 1 |
| Wallace, SS | 1 |
| Lee, AJ | 1 |
| Ali, M | 1 |
| Kim, H | 1 |
| Cleary, S | 1 |
| Cupples, C | 1 |
| Gallinger, S | 1 |
| Bristow, R | 1 |
| Chmiel, NH | 1 |
| Livingston, AL | 1 |
| David, SS | 1 |
| Gismondi, V | 1 |
| Meta, M | 1 |
| Bonelli, L | 1 |
| Radice, P | 1 |
| Sala, P | 1 |
| Bertario, L | 1 |
| Viel, A | 1 |
| Fornasarig, M | 1 |
| Arrigoni, A | 1 |
| Gentile, M | 1 |
| Ponz de Leon, M | 1 |
| Anselmi, L | 1 |
| Mareni, C | 1 |
| Bruzzi, P | 1 |
| Varesco, L | 1 |
| Bougatef, K | 1 |
| Krichene, A | 1 |
| Marrakchi, R | 1 |
| Kourda, N | 1 |
| Blondeau Lahely, Y | 1 |
| Moussa, A | 1 |
| Troudi, W | 1 |
| Jileni, SB | 1 |
| Najjar, T | 1 |
| Soubrier, F | 1 |
| Ammar Elgaaied, AB | 1 |
| Amikam, D | 1 |
| Niv, D | 1 |
| Lachter, J | 1 |
| Eidelman, S | 1 |
| Ben-Ishai, Z | 1 |
| Günther, K | 1 |
| Horbach, T | 1 |
| Hohenberger, W | 1 |
| Kraus, C | 1 |
| Ballhausen, W | 1 |
9 other studies available for adenine and Adenomatous Polyposis Coli
| Article | Year |
|---|---|
Transition state analogue of MTAP extends lifespan of APC
Topics: Adenine; Adenomatous Polyposis Coli; Animals; Disease Models, Animal; Genes, APC; Longevity; Metabol | 2021 |
Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Topics: Adenine; Adenomatous Polyposis Coli; Amino Acid Motifs; Animals; DNA; DNA Glycosylases; DNA Repair; | 2021 |
Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant.
Topics: Adenine; Adenomatous Polyposis Coli; Animals; Colorectal Neoplasms; DNA Damage; DNA Glycosylases; Es | 2019 |
Characterization of mutant MUTYH proteins associated with familial colorectal cancer.
Topics: Adenine; Adenomatous Polyposis Coli; Amino Acid Sequence; Cloning, Molecular; Colorectal Neoplasms; | 2008 |
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E.coli enzymes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adenomatous Polyposis Coli; Base Pair Mismatch; Binding Sites; | 2003 |
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.
Topics: Adenine; Adenoma; Adenomatous Polyposis Coli; Adult; Aged; Aspartic Acid; Case-Control Studies; Colo | 2004 |
Do we know all there is to know about Familial Adenomatous Polyposis?
Topics: Adenine; Adenomatous Polyposis Coli; Base Sequence; Codon; Codon, Terminator; Genes, APC; Heterozygo | 2007 |
The use of DNA markers in the pre-clinical diagnosis of familial adenomatous polyposis.
Topics: Adenine; Adenomatous Polyposis Coli; Alleles; Biomarkers, Tumor; Chromosomes, Human, Pair 5; Cytosin | 1997 |
Colonic late-onset familial adenomatous polyposis combined with severe duodenal polyposis and familial endometrial cancer.
Topics: Adenine; Adenomatous Polyposis Coli; Age of Onset; Duodenal Neoplasms; Endometrial Neoplasms; Female | 2000 |