Page last updated: 2024-10-16

adenine and AIDS-Related Opportunistic Infections

adenine has been researched along with AIDS-Related Opportunistic Infections in 22 studies

AIDS-Related Opportunistic Infections: Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.

Research Excerpts

ExcerptRelevanceReference
"to determine the impact of oral tenofovir as part of combination antiretroviral therapy on asymptomatic herpes simplex virus (HSV) shedding."7.77No impact of oral tenofovir disoproxil fumarate on herpes simplex virus shedding in HIV-infected adults. ( Kaul, R; Raboud, JM; Tan, DH; Walmsley, SL, 2011)
"Three HIV-infected patients with chronic hepatitis B (genotype A) were switched to adefovir therapy after unsuccessful lamivudine treatment."7.72Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment. ( Däumer, M; Kaiser, R; Matz, B; Rockstroh, JK; Schewe, CK; Schildgen, O; Vogel, M; Weitner, L, 2004)
"Sequential herpes simplex virus (HSV) isolates from AIDS patients receiving foscarnet therapy were evaluated for susceptibility to adefovir."7.71Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy. ( Bestman-Smith, J; Boivin, G, 2002)
" Using a computer-generated randomisation sequence, we randomly allocated antiretroviral-naive adult patients with HIV-1 and tuberculosis (aged ≥18 years with a plasma HIV RNA concentration of >1000 copies per mL) to receive raltegravir 400 mg twice a day, raltegravir 800 mg twice daily, or efavirenz 600 mg once daily plus tenofovir and lamivudine (1:1:1; stratified by country)."5.19Raltegravir for the treatment of patients co-infected with HIV and tuberculosis (ANRS 12 180 Reflate TB): a multicentre, phase 2, non-comparative, open-label, randomised trial. ( Arnold, V; Barcellos, NT; Brites, C; Chêne, G; De Castro, N; Delaugerre, C; Fagard, C; Grinsztejn, B; Madruga, JV; Molina, JM; Morgado, M; Patey, O; Pilotto, JH; Santini-Oliveira, M; Santos, BR; Veloso, VG; Vorsatz, C, 2014)
"Adefovir dipivoxil (ADF) is a novel acyclic nucleoside analogue that has recently been approved for the treatment of chronic hepatitis B virus (HBV)."4.82Adefovir dipivoxil: review of a novel acyclic nucleoside analogue. ( Danta, M; Dusheiko, G, 2004)
"to determine the impact of oral tenofovir as part of combination antiretroviral therapy on asymptomatic herpes simplex virus (HSV) shedding."3.77No impact of oral tenofovir disoproxil fumarate on herpes simplex virus shedding in HIV-infected adults. ( Kaul, R; Raboud, JM; Tan, DH; Walmsley, SL, 2011)
"Combination emtricitabine (FTC) or lamivudine (LAM) with tenofovir disoproxil (TDF) is the recommended first-line regime for treatment in chronic hepatitis B virus (HBV)/HIV co-infection."3.77Managing hepatitis B/HIV co-infected: adding entecavir to truvada (tenofovir disoproxil/emtricitabine) experienced patients. ( Beadsworth, MB; Pennell, A; Phillips, M; Ratcliffe, L; Vilar, FJ, 2011)
" We report a case of pulmonary aspergilloma in a severely immunocompromised patient with AIDS who stopped taking systemic antifungal treatment in April 1998 and remained well with little progression of invasive aspergillosis up until March 2002 when he died of acute pancreatitis related to a drug interaction of didanosine and tenofovir."3.75Long-term suppressive therapy for pulmonary aspergilloma in an immunocompromised man with AIDS. Is it always necessary? ( Yoganathan, K, 2009)
"Three HIV-infected patients with chronic hepatitis B (genotype A) were switched to adefovir therapy after unsuccessful lamivudine treatment."3.72Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment. ( Däumer, M; Kaiser, R; Matz, B; Rockstroh, JK; Schewe, CK; Schildgen, O; Vogel, M; Weitner, L, 2004)
"Sequential herpes simplex virus (HSV) isolates from AIDS patients receiving foscarnet therapy were evaluated for susceptibility to adefovir."3.71Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy. ( Bestman-Smith, J; Boivin, G, 2002)
"Adverse events, including CM immune reconstitution inflammatory syndrome (CM-IRIS), and immunologic and virologic responses were compared over 24 weeks."2.78Early versus delayed antiretroviral therapy and cerebrospinal fluid fungal clearance in adults with HIV and cryptococcal meningitis. ( Bellamy, S; Bisson, GP; Gluckman, S; Molefi, M; Rantleru, T; Ravimohan, S; Steenhoff, A; Tamuhla, N; Tebas, P; Thakur, R; Tsimako, I; Weissman, D, 2013)
"Treatment with adefovir dipivoxil for 144 weeks was well tolerated and resulted in significant and sustained reductions in HBV DNA and ALT in HIV/HBV co-infected patients."1.33Safety and efficacy of adefovir dipivoxil in patients infected with lamivudine-resistant hepatitis B and HIV-1. ( Benhamou, Y; Biao, L; Brosgart, C; Calvez, V; Chang, CG; Currie, G; Fievet, MH; Marcelin, AG; Poynard, T; Thibault, V; Vig, P; Xiong, S, 2006)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.64)18.2507
2000's11 (50.00)29.6817
2010's8 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Servato, JP1
Loyola, AM1
Spini, PH1
Spini, TH1
de Faria, PR1
Cardoso, SV1
Allen, ME1
Brown, J1
Karakas, SE1
Pollard, RB1
Grinsztejn, B1
De Castro, N1
Arnold, V1
Veloso, VG1
Morgado, M1
Pilotto, JH1
Brites, C1
Madruga, JV1
Barcellos, NT1
Santos, BR1
Vorsatz, C1
Fagard, C1
Santini-Oliveira, M1
Patey, O1
Delaugerre, C1
Chêne, G1
Molina, JM1
Romero, E1
Hernández, JM1
Jarilla, F1
Yoganathan, K1
Lavae-Mokhtari, M1
Mohammad-Khani, S1
Schmidt, RE1
Stoll, M1
Elzi, L1
Marzolini, C1
Furrer, H1
Ledergerber, B1
Cavassini, M1
Hirschel, B1
Vernazza, P1
Bernasconi, E1
Weber, R1
Battegay, M1
Tan, DH1
Kaul, R1
Raboud, JM1
Walmsley, SL1
Ratcliffe, L1
Beadsworth, MB1
Pennell, A1
Phillips, M1
Vilar, FJ1
Bisson, GP1
Molefi, M1
Bellamy, S1
Thakur, R1
Steenhoff, A1
Tamuhla, N1
Rantleru, T1
Tsimako, I1
Gluckman, S1
Ravimohan, S1
Weissman, D1
Tebas, P1
Daou, S1
Ambrosioni, J1
Merkler, D1
Calmy, A1
Danta, M1
Dusheiko, G1
Schildgen, O1
Schewe, CK1
Vogel, M1
Däumer, M1
Kaiser, R1
Weitner, L1
Matz, B1
Rockstroh, JK1
Benhamou, Y2
Thibault, V1
Vig, P1
Calvez, V1
Marcelin, AG1
Fievet, MH1
Currie, G1
Chang, CG1
Biao, L1
Xiong, S1
Brosgart, C1
Poynard, T1
Thio, CL1
Diller, R1
Thompson, K1
Cadman, J2
Bestman-Smith, J1
Boivin, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Open-label Randomized Multicenter Trial to Compare the Efficacy and Safety of Two Different Doses of Raltegravir and Efavirenz, All in Combination With Tenofovir and Lamivudine, in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuber[NCT00822315]Phase 2155 participants (Actual)Interventional2009-07-31Completed
A Randomized Clinical Trial of Immediate Versus Standard Antiretroviral Therapy for HIV-infected Adults Presenting With Cryptococcal Meningitis[NCT00976040]Phase 428 participants (Actual)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for adenine and AIDS-Related Opportunistic Infections

ArticleYear
Intracranial hypertension following highly active antiretroviral therapy interruption in an HIV-infected woman: case report and review of the literature.
    AIDS (London, England), 2013, Feb-20, Volume: 27, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; AIDS-Related Opportunistic Infections; Anti-HIV

2013
Adefovir dipivoxil: review of a novel acyclic nucleoside analogue.
    International journal of clinical practice, 2004, Volume: 58, Issue:9

    Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Resistance, Viral; Hepatitis

2004
[Treating chronic lamivudine-resistant hepatitis B in HIV co-infected patients].
    Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:10 Pt 2

    Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Drug Resistance,

2006

Trials

3 trials available for adenine and AIDS-Related Opportunistic Infections

ArticleYear
Raltegravir for the treatment of patients co-infected with HIV and tuberculosis (ANRS 12 180 Reflate TB): a multicentre, phase 2, non-comparative, open-label, randomised trial.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:6

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antitubercular Agen

2014
Early versus delayed antiretroviral therapy and cerebrospinal fluid fungal clearance in adults with HIV and cryptococcal meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 56, Issue:8

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Amphotericin B; Anti-HIV Agents; Ant

2013
Hepatitis B and adefovir depivoxil.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:2

    Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; Controlled Clinical Trials as Topi

1997

Other Studies

16 other studies available for adenine and AIDS-Related Opportunistic Infections

ArticleYear
Regression of oral Kaposi's sarcoma after combination antiretroviral therapy.
    Infection, 2013, Volume: 41, Issue:6

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-Retroviral Agents; Benzoxazines

2013
Refractory AIDS cholangiopathy: metabolic complications and the role of plasmapheresis.
    AIDS (London, England), 2013, Apr-24, Volume: 27, Issue:7

    Topics: Abdominal Pain; Acquired Immunodeficiency Syndrome; Adenine; AIDS-Related Opportunistic Infections;

2013
[Renal tuberculosis and human immunodeficiency virus infection].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:6

    Topics: Acute Kidney Injury; Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral

2009
Long-term suppressive therapy for pulmonary aspergilloma in an immunocompromised man with AIDS. Is it always necessary?
    International journal of STD & AIDS, 2009, Volume: 20, Issue:6

    Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Aspergillosis; D

2009
[Telbivudine in the management of HIV/HBV coinfection. Treating hepatitis B without HIV trouble].
    MMW Fortschritte der Medizin, 2009, Apr-30, Volume: 151, Issue:18

    Topics: Adenine; AIDS-Related Opportunistic Infections; Algorithms; Anti-HIV Agents; Antiviral Agents; Comor

2009
[Acute renal failure and hypercalcemia in an AIDS patient on tenofovir and low-dose vitamin D therapy with immune reconstitution inflammatory syndrome].
    Medizinische Klinik (Munich, Germany : 1983), 2009, Oct-15, Volume: 104, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adenine; Adrenal Cortex Hormones; Adult; AI

2009
Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.
    Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Atazanavir Sulfate;

2010
No impact of oral tenofovir disoproxil fumarate on herpes simplex virus shedding in HIV-infected adults.
    AIDS (London, England), 2011, Jan-14, Volume: 25, Issue:2

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Canada; Female; Herpes Simplex; Herpesvirus 1

2011
Managing hepatitis B/HIV co-infected: adding entecavir to truvada (tenofovir disoproxil/emtricitabine) experienced patients.
    AIDS (London, England), 2011, May-15, Volume: 25, Issue:8

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Deoxycytidine; DNA, Viral; D

2011
Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment.
    AIDS (London, England), 2004, Nov-19, Volume: 18, Issue:17

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Chronic Disease; DNA-Directe

2004
Safety and efficacy of adefovir dipivoxil in patients infected with lamivudine-resistant hepatitis B and HIV-1.
    Journal of hepatology, 2006, Volume: 44, Issue:1

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Resistance, Viral; Fem

2006
Treatment of lamivudine-resistant hepatitis B in HIV-infected persons: is adefovir dipivoxil the answer?
    Journal of hepatology, 2006, Volume: 44, Issue:1

    Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; DNA, Viral; Drug Resistance, Viral

2006
Visual loss secondary to acquired immunodeficiency virus-related progressive multifocal leukoencephalopathy demonstrating clinical improvement with highly active antiretroviral therapy.
    Optometry (St. Louis, Mo.), 2007, Volume: 78, Issue:2

    Topics: Adenine; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Hi

2007
CMV trials struggle to enroll.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:9

    Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Clinical Tri

1997
A rocky road for nucleotide analogs.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1998, Volume: 12, Issue:9

    Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topi

1998
Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy.
    Journal of medical virology, 2002, Volume: 67, Issue:1

    Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Foscarnet; Herpes Genitalis; Herpes

2002