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adenine and AIDS, Feline

adenine has been researched along with AIDS, Feline in 10 studies

Research Excerpts

ExcerptRelevanceReference
"In the present study the therapeutic efficacy and the side effects of two antiretroviral compounds used in human acquired immunodeficiency syndrome (AIDS) research, 3'-azido-2',3'-dideoxythymidine (AZT, zidovudine, Retrovir) and 9-(2-phosphonylmethoxyethyl)adenine (PMEA), were investigated in the treatment of cats naturally infected with feline immunodeficiency virus (FIV) and cats naturally infected with feline leukemia virus (FeLV)."5.07Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms. ( Beer, B; Donath, A; Egberink, HF; Hartmann, K; Hoffmann-Fezer, G; Horzinek, MC; Lutz, H; Thefeld, S; Thum, I, 1992)
" Nine cats received PMEA at a dosage of 10 mg/kg body weight, nine cats received FPMPA at a dosage of 25 mg/kg body weight."2.68[Comparative investigation of the efficacy of two nucleocapsid analogs in FIV infected cats]. ( Balzarini, J; Erfle, V; Goebel, F; Goldberg, M; Hartmann, K; Kuffer, M; Rolinski, B, 1997)
" Cytotoxicity was less than for PMEA or azidothymidine (AZT) for culture periods of 7 days, but more toxic after 10 days."1.30Toxicity associated with high dosage 9-[(2R,5R-2,5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy off attempts to abort early FIV infection. ( Ferk, G; Hartmann, K; North, TW; Pedersen, NC, 1997)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (80.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taffin, E1
Paepe, D1
Goris, N1
Auwerx, J1
Debille, M1
Neyts, J1
Van de Maele, I1
Daminet, S1
Hartmann, AD1
Wilhelm, N1
Balzarini, J4
Hartmann, K5
Vahlenkamp, TW1
De Ronde, A1
Naesens, L2
De Clercq, E2
van Eijk, MJ1
Horzinek, MC3
Egberink, HF3
Ferk, G1
North, TW1
Pedersen, NC1
Kuffer, M2
Rolinski, B1
Goebel, F1
Erfle, V2
Goldberg, M2
Goebel, FD1
Jindrich, J1
Holy, A1
Bischofberger, N1
Kraft, W1
Philpott, MS1
Ebner, JP2
Hoover, EA2
Donath, A1
Beer, B1
Lutz, H1
Hoffmann-Fezer, G1
Thum, I1
Thefeld, S1
Zeidner, NS1
Mullins, JI1
Hartman, K1

Reviews

1 review available for adenine and AIDS, Feline

ArticleYear
Chemotherapy of feline immunodeficiency virus infection.
    Journal of the American Veterinary Medical Association, 1991, Nov-15, Volume: 199, Issue:10

    Topics: Adenine; Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Immunodeficienc

1991

Trials

4 trials available for adenine and AIDS, Feline

ArticleYear
Clinical efficacy of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine (PMPDAP) in the treatment of feline immunodeficiency virus-infected cats.
    Journal of feline medicine and surgery, 2012, Volume: 14, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Biopterins; Cats; CD4-CD8 Ratio; Double-Blind Method; Feline Acq

2012
[Comparative investigation of the efficacy of two nucleocapsid analogs in FIV infected cats].
    Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, 1997, Volume: 25, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; Cats; Double-Blind Method; Feline Acquired Immunodeficiency Synd

1997
Efficacy of the acyclic nucleoside phosphonates (S)-9-(3-fluoro-2-phosphonylmethoxypropyl)adenine (FPMPA) and 9-(2-phosphonylmethoxyethyl)adenine (PMEA) against feline immunodeficiency virus.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Feb-01, Volume: 17, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Cats; CD4 Lymphocyte Count; Double-Blind Method; Feline Acquired

1998
Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms.
    Veterinary immunology and immunopathology, 1992, Volume: 35, Issue:1-2

    Topics: Adenine; Animals; Antiviral Agents; Cats; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Double-Blind Me

1992

Other Studies

5 other studies available for adenine and AIDS, Feline

ArticleYear
Antiviral treatment of feline immunodeficiency virus-infected cats with (R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine.
    Journal of feline medicine and surgery, 2015, Volume: 17, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Humans; Immunod

2015
(R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine is a potent inhibitor of feline immunodeficiency virus infection.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:3

    Topics: Adenine; Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Immunodeficienc

1995
Toxicity associated with high dosage 9-[(2R,5R-2,5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy off attempts to abort early FIV infection.
    Antiviral research, 1997, Volume: 36, Issue:1

    Topics: Adenine; Animals; Antibodies, Viral; Antiviral Agents; Cats; Cells, Cultured; Enzyme-Linked Immunoso

1997
Evaluation of 9-(2-phosphonylmethoxyethyl) adenine therapy for feline immunodeficiency virus using a quantitative polymerase chain reaction.
    Veterinary immunology and immunopathology, 1992, Volume: 35, Issue:1-2

    Topics: Adenine; Animals; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Base Sequence; Cats; DNA, Vi

1992
Early therapy of feline leukemia virus infection (FeLV-FAIDS) with 9-(2-phosphonylmethoxyethyl)adenine (PMEA).
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Adenine; Animals; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Cats; Cell Line; Feline Acqu

1991