adenine has been researched along with AIDS, Feline in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study the therapeutic efficacy and the side effects of two antiretroviral compounds used in human acquired immunodeficiency syndrome (AIDS) research, 3'-azido-2',3'-dideoxythymidine (AZT, zidovudine, Retrovir) and 9-(2-phosphonylmethoxyethyl)adenine (PMEA), were investigated in the treatment of cats naturally infected with feline immunodeficiency virus (FIV) and cats naturally infected with feline leukemia virus (FeLV)." | 5.07 | Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms. ( Beer, B; Donath, A; Egberink, HF; Hartmann, K; Hoffmann-Fezer, G; Horzinek, MC; Lutz, H; Thefeld, S; Thum, I, 1992) |
| " Nine cats received PMEA at a dosage of 10 mg/kg body weight, nine cats received FPMPA at a dosage of 25 mg/kg body weight." | 2.68 | [Comparative investigation of the efficacy of two nucleocapsid analogs in FIV infected cats]. ( Balzarini, J; Erfle, V; Goebel, F; Goldberg, M; Hartmann, K; Kuffer, M; Rolinski, B, 1997) |
| " Cytotoxicity was less than for PMEA or azidothymidine (AZT) for culture periods of 7 days, but more toxic after 10 days." | 1.30 | Toxicity associated with high dosage 9-[(2R,5R-2,5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy off attempts to abort early FIV infection. ( Ferk, G; Hartmann, K; North, TW; Pedersen, NC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taffin, E | 1 |
| Paepe, D | 1 |
| Goris, N | 1 |
| Auwerx, J | 1 |
| Debille, M | 1 |
| Neyts, J | 1 |
| Van de Maele, I | 1 |
| Daminet, S | 1 |
| Hartmann, AD | 1 |
| Wilhelm, N | 1 |
| Balzarini, J | 4 |
| Hartmann, K | 5 |
| Vahlenkamp, TW | 1 |
| De Ronde, A | 1 |
| Naesens, L | 2 |
| De Clercq, E | 2 |
| van Eijk, MJ | 1 |
| Horzinek, MC | 3 |
| Egberink, HF | 3 |
| Ferk, G | 1 |
| North, TW | 1 |
| Pedersen, NC | 1 |
| Kuffer, M | 2 |
| Rolinski, B | 1 |
| Goebel, F | 1 |
| Erfle, V | 2 |
| Goldberg, M | 2 |
| Goebel, FD | 1 |
| Jindrich, J | 1 |
| Holy, A | 1 |
| Bischofberger, N | 1 |
| Kraft, W | 1 |
| Philpott, MS | 1 |
| Ebner, JP | 2 |
| Hoover, EA | 2 |
| Donath, A | 1 |
| Beer, B | 1 |
| Lutz, H | 1 |
| Hoffmann-Fezer, G | 1 |
| Thum, I | 1 |
| Thefeld, S | 1 |
| Zeidner, NS | 1 |
| Mullins, JI | 1 |
| Hartman, K | 1 |
1 review available for adenine and AIDS, Feline
| Article | Year |
|---|---|
Chemotherapy of feline immunodeficiency virus infection.
Topics: Adenine; Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Immunodeficienc | 1991 |
4 trials available for adenine and AIDS, Feline
| Article | Year |
|---|---|
Clinical efficacy of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine (PMPDAP) in the treatment of feline immunodeficiency virus-infected cats.
Topics: Adenine; Animals; Antiviral Agents; Biopterins; Cats; CD4-CD8 Ratio; Double-Blind Method; Feline Acq | 2012 |
[Comparative investigation of the efficacy of two nucleocapsid analogs in FIV infected cats].
Topics: Adenine; Animals; Antiviral Agents; Cats; Double-Blind Method; Feline Acquired Immunodeficiency Synd | 1997 |
Efficacy of the acyclic nucleoside phosphonates (S)-9-(3-fluoro-2-phosphonylmethoxypropyl)adenine (FPMPA) and 9-(2-phosphonylmethoxyethyl)adenine (PMEA) against feline immunodeficiency virus.
Topics: Adenine; Animals; Antiviral Agents; Cats; CD4 Lymphocyte Count; Double-Blind Method; Feline Acquired | 1998 |
Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms.
Topics: Adenine; Animals; Antiviral Agents; Cats; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Double-Blind Me | 1992 |
5 other studies available for adenine and AIDS, Feline
| Article | Year |
|---|---|
Antiviral treatment of feline immunodeficiency virus-infected cats with (R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine.
Topics: Adenine; Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Humans; Immunod | 2015 |
(R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine is a potent inhibitor of feline immunodeficiency virus infection.
Topics: Adenine; Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Immunodeficienc | 1995 |
Toxicity associated with high dosage 9-[(2R,5R-2,5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy off attempts to abort early FIV infection.
Topics: Adenine; Animals; Antibodies, Viral; Antiviral Agents; Cats; Cells, Cultured; Enzyme-Linked Immunoso | 1997 |
Evaluation of 9-(2-phosphonylmethoxyethyl) adenine therapy for feline immunodeficiency virus using a quantitative polymerase chain reaction.
Topics: Adenine; Animals; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Base Sequence; Cats; DNA, Vi | 1992 |
Early therapy of feline leukemia virus infection (FeLV-FAIDS) with 9-(2-phosphonylmethoxyethyl)adenine (PMEA).
Topics: Adenine; Animals; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Cats; Cell Line; Feline Acqu | 1991 |