Compounds > adamantane
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adamantane and Pancreatic Neoplasms

adamantane has been researched along with Pancreatic Neoplasms in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's15 (83.33)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Carvalho, MFL; de Almeida, BO; de Miranda, LBL; Lima, K; Lipreri da Silva, JC; Machado-Neto, JA1
Dicembrini, I; Mannucci, E; Monami, M; Montereggi, C; Nreu, B1
Arima, H1
Anders, R; Begum, A; Chang, YT; Ewachiw, T; Gocke, C; Li, J; Maitra, A; Marchionni, L; Matsui, W; McMillan, RH; Penchev, VR; Rasheed, Z; Uren, A; Wang, Q1
Das, JK; Dawson, MI; Farhana, L; Fontana, JA; Murshed, F; Rishi, AK1
Bhatt, DL; Buskila, A; Greenberger, N; Hirshberg, B; Im, K; Iqbal, N; Lerch, MM; Mosenzon, O; Raz, I; Scirica, BM; Stahre, C; Umez-Eronini, A1
Choi, SA; Jang, JY; Jung, HS; Kim, HC; Kim, JH; Kim, MJ; Kim, SW; Lee, HM; Lee, KB; Ohn, JH; Park, KS; Yoon, JW1
Dawson, MI; Farhana, L; Fontana, JA1
Drake, RR; Gao, P; Jones, EE; Norris, JS; Smith, CD1
Giannuzzo, A; Novak, I; Pedersen, SF1
Alves, F; Ellegaard, M; Giannuzzo, A; Napp, J; Novak, I; Saccomano, M1
Lewis, CS; Smith, CD; Voelkel-Johnson, C1
Jütte, H; Meier, J; Montanya, E; Nauck, M; Schmidt, W; Tannapfel, A; Ueberberg, S; Uhl, W1
Abel, ED; Kuwada, S; Park, K; Soto, J; Viswanath, G; Wang, L; Zhang, Y1
Beljanski, V; Knaak, C; Smith, CD; Zhuang, Y1
Bourguignon, JJ; Dimas, K; Eleutheriades, A; Foscolos, GB; Georgakopoulou, S; Khan, H; Kourafalos, VN; Mirjolet, JF; Moutsos, VI; Papanastasiou, I; Pondiki, S; Prassa, M; Riganas, S; Serin, G; Theodoropoulou, M; Tsotinis, A; Vamvakides, A; Zaniou, A1
Busch, SJ; Foley, JE; Hoffmann, P; Johnson, R; Kothny, W; Meyer, F; Sahota, P1
Dimas, K; Eleutheriades, A; Foscolos, GB; Georgakopoulou, S; Khan, H; Kourafalos, VN; Mantelas, A; Mirjolet, JF; Moutsos, VI; Papanastasiou, I; Pondiki, S; Prassa, M; Riganas, S; Serin, G; Theodoropoulou, M; Tsotinis, A; Vamvakides, A; Zaniou, A1

Reviews

2 review(s) available for adamantane and Pancreatic Neoplasms

ArticleYear
Pancreatitis and pancreatic cancer in patientes treated with Dipeptidyl Peptidase-4 inhibitors: An extensive and updated meta-analysis of randomized controlled trials.
    Diabetes research and clinical practice, 2020, Volume: 159

    Topics: Adamantane; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Hypoglycemic Agents; Pancreatic Neoplasms; Pancreatitis; Randomized Controlled Trials as Topic; Sitagliptin Phosphate

2020
[Delivery of Anticancer Drugs Using a Supramolecular Complex to Cancer Tissues Having High Interstitial Fluid Pressure].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2020, Volume: 140, Issue:5

    Topics: Adamantane; Antineoplastic Agents; beta-Cyclodextrins; Body Fluids; Bromelains; Drug Delivery Systems; Humans; Macromolecular Substances; Pancreatic Neoplasms; Polyethylene Glycols; Pressure

2020

Trials

2 trial(s) available for adamantane and Pancreatic Neoplasms

ArticleYear
Incidence of pancreatitis and pancreatic cancer in a randomized controlled multicenter trial (SAVOR-TIMI 53) of the dipeptidyl peptidase-4 inhibitor saxagliptin.
    Diabetes care, 2014, Volume: 37, Issue:9

    Topics: Adamantane; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Humans; Incidence; International Agencies; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis; Prognosis; Risk Factors

2014
Improved Insulin Secretion by Autologous Islet Transplantation, Compared to Oral Antidiabetic Agents, After Distal Pancreatectomy.
    Cell transplantation, 2015, Volume: 24, Issue:8

    Topics: Adamantane; Administration, Oral; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; HMGB1 Protein; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans Transplantation; Male; Metformin; Middle Aged; Nitriles; Pancreatectomy; Pancreatic Neoplasms; Pyrrolidines; Transplantation, Autologous; Vascular Endothelial Growth Factor A; Vildagliptin

2015

Other Studies

14 other study(ies) available for adamantane and Pancreatic Neoplasms

ArticleYear
NSC305787, a pharmacological ezrin inhibitor, exhibits antineoplastic activity in pancreatic cancer cells.
    Investigational new drugs, 2022, Volume: 40, Issue:4

    Topics: Adamantane; Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cytoskeletal Proteins; Humans; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Quinolines

2022
Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma.
    Molecular cancer research : MCR, 2019, Volume: 17, Issue:4

    Topics: Actins; Adamantane; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cytoskeletal Proteins; Heterografts; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Pancreatic Neoplasms; Quinolines

2019
Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adamantane; Apoptosis; CD24 Antigen; Cell Line, Tumor; Cinnamates; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, bcl-2; Humans; Hyaluronan Receptors; MicroRNAs; Neoplastic Stem Cells; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myb; Receptor, IGF Type 1; Spheroids, Cellular; Tumor Cells, Cultured

2013
Down regulation of miR-202 modulates Mxd1 and Sin3A repressor complexes to induce apoptosis of pancreatic cancer cells.
    Cancer biology & therapy, 2015, Volume: 16, Issue:1

    Topics: 3' Untranslated Regions; Adamantane; Apoptosis; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line, Tumor; Cinnamates; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Pancreatic Neoplasms; Protein Binding; Repressor Proteins; RNA Interference; Sin3 Histone Deacetylase and Corepressor Complex; Telomerase

2015
Tissue biomarkers of drug efficacy: case studies using a MALDI-MSI workflow.
    Bioanalysis, 2015, Volume: 7, Issue:20

    Topics: Adamantane; Animals; Biomarkers, Tumor; Ceramides; Disease Models, Animal; Humans; Kidney Neoplasms; Lysophospholipids; Mice; Pancreatic Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sphingosine; Transplantation, Heterologous

2015
The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells.
    Molecular cancer, 2015, Nov-25, Volume: 14

    Topics: Adamantane; Adenosine Triphosphate; Aminoquinolines; Apoptosis; Carcinoma, Pancreatic Ductal; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Movement; Cell Survival; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyridines; Receptors, Purinergic P2X7; Tetrazoles

2015
Targeting of the P2X7 receptor in pancreatic cancer and stellate cells.
    International journal of cancer, 2016, 12-01, Volume: 139, Issue:11

    Topics: Adamantane; Aminoquinolines; Animals; Carcinoma, Pancreatic Ductal; Cell Growth Processes; Cell Line, Tumor; Heterografts; Humans; Luminescent Measurements; Male; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Pancreatic Neoplasms; Pancreatic Stellate Cells; Receptors, Purinergic P2X7

2016
Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640.
    Oncotarget, 2016, Sep-13, Volume: 7, Issue:37

    Topics: Acetylation; Adamantane; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Synergism; Gemcitabine; Gene Expression Regulation, Neoplastic; Histones; Humans; Pancreatic Neoplasms; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-myc; Pyridines; Retinoblastoma Protein; Ribonucleoside Diphosphate Reductase

2016
Histological changes in endocrine and exocrine pancreatic tissue from patients exposed to incretin-based therapies.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:12

    Topics: Acinar Cells; Adamantane; Adenocarcinoma; Adult; Aged; Carcinoma in Situ; Case-Control Studies; Cystadenoma; Diabetes Mellitus, Type 2; Digestive System Surgical Procedures; Dipeptides; Exenatide; Female; Glucagon; Glucagon-Secreting Cells; Humans; Incretins; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Middle Aged; Neuroendocrine Tumors; Nitriles; Organ Size; Pancreas; Pancreas, Exocrine; Pancreatic Neoplasms; Pancreatitis, Chronic; Peptides; Pyrrolidines; Sitagliptin Phosphate; Tissue Donors; Venoms; Vildagliptin

2016
Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth.
    Molecular and cellular biology, 2010, Volume: 30, Issue:6

    Topics: Adamantane; Animals; Apoptosis; Cell Nucleus; Cell Proliferation; Cell Respiration; Cinnamates; Cytochromes c; Fibroblasts; Gene Deletion; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Hepatocytes; Mice; Mitochondria; Pancreatic Neoplasms; Protein Binding; Protein Stability; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Receptors, Death Domain; Retinoids; Signal Transduction

2010
Combined anticancer effects of sphingosine kinase inhibitors and sorafenib.
    Investigational new drugs, 2011, Volume: 29, Issue:6

    Topics: Adamantane; Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Caspase 3; Caspase 7; Catechols; Cell Line, Tumor; DNA Fragmentation; Drug Synergism; Female; Humans; Kidney Neoplasms; Mice; Mice, SCID; Niacinamide; Pancreatic Neoplasms; Phenylurea Compounds; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Sorafenib; Xenograft Model Antitumor Assays

2011
Synthesis, σ₁, σ₂-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.
    Bioorganic & medicinal chemistry, 2012, May-15, Volume: 20, Issue:10

    Topics: Adamantane; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Molecular Structure; Pancreatic Neoplasms; Receptors, sigma

2012
Studies in rodents with the dipeptidyl peptidase-4 inhibitor vildagliptin to evaluate possible drug-induced pancreatic histological changes that are predictive of pancreatitis and cancer development in man.
    Diabetes, obesity & metabolism, 2013, Volume: 15, Issue:1

    Topics: Adamantane; Animals; Dipeptidyl-Peptidase IV Inhibitors; Female; Humans; Islets of Langerhans; Male; Mice; Mice, Transgenic; Nitriles; Pancreas, Exocrine; Pancreatic Neoplasms; Pancreatitis; Predictive Value of Tests; Pyrrolidines; Rats; Rats, Transgenic; Rats, Wistar; Vildagliptin

2013
New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Female; Humans; Male; Mice; Mice, SCID; Molecular Structure; Neuralgia; Ovarian Neoplasms; Pancreatic Neoplasms; Piperidines; Prostatic Neoplasms; Protein Binding; Receptors, sigma; Structure-Activity Relationship; Tumor Cells, Cultured

2012