Compounds > adamantane
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adamantane and Ovarian Neoplasms

adamantane has been researched along with Ovarian Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Czajkowski, K; Lasek, W; Sieńko, J; Smolarczyk, R; Teliga-Czajkowska, J1
Antoon, JW; Beckman, BS; Chan, L; White, MD1
Benedetti, V; De Cesare, M; Zuco, V; Zunino, F1
Bagnati, R; Capocasa, F; D'Incalci, M; Marangon, E; Pace, S; Sala, F; Zucchetti, M1
Brard, L; Horan, TC; Kim, KK; Lange, TS; Moore, RG; Singh, AP; Singh, RK; Vorsa, N1
Dimas, K; Eleutheriades, A; Foscolos, GB; Georgakopoulou, S; Khan, H; Kourafalos, VN; Mantelas, A; Mirjolet, JF; Moutsos, VI; Papanastasiou, I; Pondiki, S; Prassa, M; Riganas, S; Serin, G; Theodoropoulou, M; Tsotinis, A; Vamvakides, A; Zaniou, A1
Basak, G; Czajkowski, K; Dziembowska, M; Górska, A; Gołab, J; Grzela, T; Jalili, A; Kamińska, B; Kasprzycka, M; Kazimierczuk, Z; Lasek, W; Maj, M; Mikłaszewicz, P; Młynarczuk, I; Nowaczyk, M; Nowis, D; Sieńko, J; Switaj, T1
Carminati, P; Cincinelli, R; Dallavalle, S; Gaetano, C; Giannini, G; Illy, B; Merlini, L; Penco, S; Pisano, C; Supino, R; Vesci, L; Zuco, V; Zunino, F1
Cassinelli, G; Garattini, E; Giordano, V; Lanzi, C; Pisano, C; Supino, R; Zanchi, C; Zanier, R; Zuco, V; Zunino, F1
Lanzi, C; Supino, R; Zanchi, C; Zuco, V; Zunino, F1
De Cesare, M; Ferrara, FF; Foderà, R; Pisano, C; Pratesi, G; Rossi, C; Supino, R; Vesci, L; Zuco, V; Zunino, F1

Trials

1 trial(s) available for adamantane and Ovarian Neoplasms

ArticleYear
Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of ST1926, a novel oral antitumor agent, adamantyl retinoid derivative, in plasma of patients in a Phase I study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-01, Volume: 877, Issue:27

    Topics: Adamantane; Antineoplastic Agents; Calibration; Chromatography, High Pressure Liquid; Cinnamates; Drug Stability; Female; Humans; Linear Models; Ovarian Neoplasms; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2009

Other Studies

10 other study(ies) available for adamantane and Ovarian Neoplasms

ArticleYear
Potentialization of N-a-tosyl-L-phenylalanine chloromethyl ketone (TPCK) cytotoxic activity by 2-(1-adamantylamino)-6-methylpyridine (AdAMP) in human ovarian cancer cells.
    Ginekologia polska, 2017, Volume: 88, Issue:6

    Topics: Adamantane; Aminopyridines; Apoptosis; Cell Line, Tumor; Cell Survival; Drug Synergism; Female; Humans; Infliximab; Ovarian Neoplasms; Signal Transduction; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2017
Targeting ovarian cancer and chemoresistance through selective inhibition of sphingosine kinase-2 with ABC294640.
    Anticancer research, 2013, Volume: 33, Issue:9

    Topics: Adamantane; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Ovarian Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Pyridines

2013
Sensitization of ovarian carcinoma cells to the atypical retinoid ST1926 by the histone deacetylase inhibitor, RC307: enhanced DNA damage response.
    International journal of cancer, 2010, Mar-01, Volume: 126, Issue:5

    Topics: Adamantane; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cinnamates; DNA Damage; Enzyme Inhibitors; Female; Histone Deacetylases; Humans; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Retinoids; Xenograft Model Antitumor Assays

2010
Cytotoxic properties of Adamantyl isothiocyanate and potential in vivo metabolite adamantyl-N-acetylcystein in gynecological cancer cells.
    Chemical biology & drug design, 2012, Volume: 79, Issue:1

    Topics: Acetylcysteine; Adamantane; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Female; G2 Phase Cell Cycle Checkpoints; Humans; Isothiocyanates; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Protein Kinase Inhibitors; Reactive Oxygen Species

2012
New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Female; Humans; Male; Mice; Mice, SCID; Molecular Structure; Neuralgia; Ovarian Neoplasms; Pancreatic Neoplasms; Piperidines; Prostatic Neoplasms; Protein Binding; Receptors, sigma; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Stimulation of TNF-alpha production by 2-(1-adamantylamino)-6-methylpyridine (AdAMP) - a novel immunomodulator with potential application in tumour immunotherapy.
    Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:3

    Topics: Adamantane; Aminopyridines; Animals; Female; Humans; Melanoma; Mice; NF-kappa B; Ovarian Neoplasms; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
A novel atypical retinoid endowed with proapoptotic and antitumor activity.
    Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6

    Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Cinnamates; DNA Damage; Drug Screening Assays, Antitumor; Female; Humans; Melanoma; Mice; Mice, Nude; Ovarian Neoplasms; Protein Isoforms; Receptors, Retinoic Acid; Retinoids; Structure-Activity Relationship; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured

2003
Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid.
    Cell death and differentiation, 2004, Volume: 11, Issue:3

    Topics: Adamantane; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma; Caspases; Cell Division; Cell Line, Tumor; Cinnamates; DNA Damage; DNA Repair; DNA, Neoplasm; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinases; Molecular Structure; Ovarian Neoplasms; Proliferating Cell Nuclear Antigen; Stress, Physiological; Transcription Factor AP-1; Tumor Suppressor Protein p53

2004
Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839.
    Cancer research, 2005, Mar-15, Volume: 65, Issue:6

    Topics: Adamantane; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Caspase 8; Caspases; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cinnamates; DNA Damage; Drug Synergism; Enzyme Activation; ErbB Receptors; Female; Gefitinib; Humans; Ovarian Neoplasms; Quinazolines; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; Vulvar Neoplasms

2005
Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:9

    Topics: Adamantane; Animals; Antineoplastic Combined Chemotherapy Protocols; Cinnamates; Cisplatin; Female; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2007