Page last updated: 2024-08-21

adamantane and Orthomyxoviridae Infections

adamantane has been researched along with Orthomyxoviridae Infections in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199015 (65.22)18.7374
1990's1 (4.35)18.2507
2000's0 (0.00)29.6817
2010's5 (21.74)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Duncan, MC; Fedida, D; Jalily, PH; Tietjen, I; Wang, J1
Dong, G; He, W; Wang, C; Wu, Q; Xie, Y; Xu, H; Yan, H; Zhang, W1
Hahm, B; Seo, YJ; Studstill, CJ; Vijayan, M; Wolf, JJ; Xia, C1
Bahl, J; Baranovich, T; Culhane, M; Darnell, D; Govorkova, EA; Kaplan, BS; Lowe, JF; Marathe, BM; Stigger-Rosser, E; Webby, RJ1
DeGrado, WF; Hu, Y; Ma, C; Musharrafieh, R; Smee, DF; Wang, J; Zhang, J1
Chou, KC; Du, QS; Huang, RB; Wang, SQ1
Basler, CF; Fytas, C; Fytas, G; Kolocouris, A; Valmas, C; Zoidis, G1
Błoch, P; Denys, A; Korczak, E; Kulig, A; Sygut, J1
Aleksandrov, BA; Anisimov, WN; Likhachev, AIa; Okulov, VB; Pozharisskiĭ, KM1
Cogolli, P; Fioretti, MC; Pellicciari, R; Tiecco, M1
Arensman, JB; Dominik, JW; Hilmas, DE1
Berendt, RF; Dominik, JW; Stephen, EL; Walker, JS; Young, HW1
Bauer, DJ; Tisdale, M1
Kramer, MJ; Levitan, P; Tilley, JW1
Arensman, JB; Hilmas, DE; Tschorn, RR1
Galegov, GA; Obrosova-Serova, NP; Pushkarskaya, NL; Zhdanov, VM1
Dominik, JW; Moe, JB; Spertzel, RO; Stephen, EL; Walker, JS1
Bruns, M; Ennis, FA; Herrmann, JE; West, K2
Zhirnov, OP1
Blasecki, JW; Gaylord, JC; Hoffman, HE; Shalaby, LM; Whitney, CC1
Gegova, G; Maksimova-Todorova, V; Manolova, N; Serkedzhieva, Iu1
Bean, WJ; Kawaoka, Y; Webster, RG1

Reviews

1 review(s) available for adamantane and Orthomyxoviridae Infections

ArticleYear
Put a cork in it: Plugging the M2 viral ion channel to sink influenza.
    Antiviral research, 2020, Volume: 178

    Topics: Adamantane; Animals; Antiviral Agents; Drug Development; Drug Discovery; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Ion Channels; Orthomyxoviridae Infections; Viral Matrix Proteins; Virus Replication

2020

Other Studies

22 other study(ies) available for adamantane and Orthomyxoviridae Infections

ArticleYear
Distribution and evolution of H1N1 influenza A viruses with adamantanes-resistant mutations worldwide from 1918 to 2019.
    Journal of medical virology, 2021, Volume: 93, Issue:6

    Topics: Adamantane; Animals; Antiviral Agents; Drug Resistance, Viral; Europe; Evolution, Molecular; Host Specificity; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; North America; Orthomyxoviridae Infections; Phylogeny; Swine; Viral Proteins

2021
Transient inhibition of sphingosine kinases confers protection to influenza A virus infected mice.
    Antiviral research, 2018, Volume: 158

    Topics: A549 Cells; Adamantane; Administration, Oral; Amino Alcohols; Aminophenols; Animals; Cell Line; Disease Models, Animal; Female; Gene Knockdown Techniques; HEK293 Cells; Humans; Influenza A virus; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Isoforms; Pyridines; RNA, Small Interfering; Sphingosine; Thiazoles; Virus Replication

2018
Influenza A viruses of swine circulating in the United States during 2009-2014 are susceptible to neuraminidase inhibitors but show lineage-dependent resistance to adamantanes.
    Antiviral research, 2015, Volume: 117

    Topics: Acids, Carbocyclic; Adamantane; Amino Acid Substitution; Animals; Antiviral Agents; Base Sequence; Cyclopentanes; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Genotype; Guanidines; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H1N2 Subtype; Influenza A Virus, H3N2 Subtype; Madin Darby Canine Kidney Cells; Mutation, Missense; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Phenotype; Phylogeny; Swine; Swine Diseases; Time Factors; United States; Viral Proteins; Zanamivir

2015
An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses.
    Antiviral research, 2017, Volume: 140

    Topics: Adamantane; Amantadine; Animals; Antiviral Agents; Dogs; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Inhibitory Concentration 50; Madin Darby Canine Kidney Cells; Molecular Dynamics Simulation; Mutation; Orthomyxoviridae Infections; Spiro Compounds; Structure-Activity Relationship; Viral Matrix Proteins

2017
Designing inhibitors of M2 proton channel against H1N1 swine influenza virus.
    PloS one, 2010, Feb-23, Volume: 5, Issue:2

    Topics: Adamantane; Amino Acid Sequence; Animals; Antiviral Agents; Binding Sites; Drug Design; Drug Resistance, Viral; Influenza A Virus, H1N1 Subtype; Ion Channels; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Orthomyxoviridae Infections; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rimantadine; Sequence Homology, Amino Acid; Swine; Swine Diseases; Viral Matrix Proteins

2010
Influence of an additional amino group on the potency of aminoadamantanes against influenza virus A. II - Synthesis of spiropiperazines and in vitro activity against influenza A H3N2 virus.
    Bioorganic chemistry, 2010, Volume: 38, Issue:6

    Topics: Adamantane; Animals; Antiviral Agents; Cell Line; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Orthomyxoviridae Infections; Piperazines; Spiro Compounds

2010
[Antiviral activity of remantadine evaluated by a pathomorphological study of the lungs of mice infected by influenza virus].
    Medycyna doswiadczalna i mikrobiologia, 1984, Volume: 36, Issue:4

    Topics: Adamantane; Animals; Influenza A virus; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Rimantadine

1984
[Results of tests for carcinogenic, teratogenic and embryotoxic action of remantadin].
    Voprosy onkologii, 1982, Volume: 28, Issue:9

    Topics: Abnormalities, Drug-Induced; Adamantane; Animals; Embryo, Mammalian; Female; Male; Mice; Neoplasms, Experimental; Orthomyxoviridae Infections; Rats; Rimantadine

1982
Adamantane derivatives of biological interest. Synthesis and antiviral activity of 2-(1-adamantyl)imidazole derivatives.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:12

    Topics: Adamantane; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Female; Influenza A virus; Lethal Dose 50; Male; Mice; Orthomyxoviridae Infections

1980
Effects of small-particle aerosols of rimantadine and ribavirin on arterial blood pH and gas tensions and lung water content of A2 influenza-infected mice.
    Antimicrobial agents and chemotherapy, 1977, Volume: 12, Issue:1

    Topics: Adamantane; Aerosols; Animals; Blood Gas Analysis; Bridged-Ring Compounds; Female; Hydrogen-Ion Concentration; Lung; Mice; Orthomyxoviridae Infections; Ribavirin; Ribonucleosides; Time Factors; Water

1977
Aerosol therapy of influenza infections of mice and primates with rimantadine, ribavirin, and related compounds.
    Annals of the New York Academy of Sciences, 1977, Mar-04, Volume: 284

    Topics: Adamantane; Aerosols; Animals; Antiviral Agents; Bridged-Ring Compounds; Female; Haplorhini; Mice; Orthomyxoviridae Infections; Ribavirin; Ribonucleosides; Saimiri

1977
The relative potencies of anti-influenza compounds.
    Annals of the New York Academy of Sciences, 1977, Mar-04, Volume: 284

    Topics: Adamantane; Amantadine; Amines; Animals; Antiviral Agents; Cells, Cultured; Cycloparaffins; Influenza A virus; Mice; Microbial Sensitivity Tests; Orthomyxoviridae Infections; Ribavirin

1977
Adamantylthiourea derivatives as antiviral agents.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:8

    Topics: Adamantane; Amantadine; Animals; Antiviral Agents; Lethal Dose 50; Mice; Orthomyxoviridae Infections; Thiourea

1979
Effect of small-particle aerosols of rimantadine and ribavirin on pathophysiologic changes associated with A/NJ influenza in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:3

    Topics: Adamantane; Aerosols; Animals; Antiviral Agents; Body Weight; Bridged-Ring Compounds; Female; Influenza A virus; Lung; Mice; Organ Size; Orthomyxoviridae Infections; Oxygen; Ribavirin; Ribonucleosides; Time Factors

1978
Combined action of ribovirin and rimantadine in experimental myxovirus infection.
    Experientia, 1977, Jul-15, Volume: 33, Issue:7

    Topics: Adamantane; Animals; Antiviral Agents; Bridged-Ring Compounds; Cells, Cultured; Chick Embryo; Fibroblasts; Mice; Orthomyxoviridae; Orthomyxoviridae Infections; Ribavirin; Ribonucleosides; Virus Replication

1977
Treatment of influenza infection of mice by using rimantadine hydrochlorides by the aerosol and intraperitoneal routes.
    Antimicrobial agents and chemotherapy, 1975, Volume: 8, Issue:2

    Topics: Adamantane; Aerosols; Animals; Bridged-Ring Compounds; Female; Injections, Intraperitoneal; Lung; Mice; Orthomyxoviridae Infections

1975
Effect of rimantadine on cytotoxic T lymphocyte responses and immunity to reinfection in mice infected with influenza A virus.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:2

    Topics: Adamantane; Animals; Antibodies, Viral; Influenza A virus; Male; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Recurrence; Rimantadine; T-Lymphocytes, Cytotoxic

1990
High protection of animals lethally infected with influenza virus by aprotinin-rimantadine combination.
    Journal of medical virology, 1987, Volume: 21, Issue:2

    Topics: Adamantane; Animals; Aprotinin; Drug Combinations; Drug Synergism; Influenza A virus; Lung; Mice; Orthomyxoviridae Infections; Rimantadine

1987
Efficacy of rimantadine hydrochloride in the treatment of influenza infection of mice.
    Antiviral research, 1989, Volume: 11, Issue:3

    Topics: Adamantane; Administration, Oral; Animals; Disease Models, Animal; Influenza A virus; Injections, Intraperitoneal; Lung; Male; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Rimantadine

1989
Pharmacokinetics and metabolism of rimantadine hydrochloride in mice and dogs.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11

    Topics: Adamantane; Administration, Oral; Amantadine; Animals; Biological Availability; Dogs; Dose-Response Relationship, Drug; Feces; Female; Gas Chromatography-Mass Spectrometry; Lung; Metabolic Clearance Rate; Mice; Orthomyxoviridae Infections; Rimantadine

1988
[Combined action of antiviral substances of natural and synthetic origin. I. The anti-influenza action of a combination of the polyphenol complex isolated from Geranium sanguineum L. and remantadine in vitro and in ovo].
    Acta microbiologica Bulgarica, 1986, Volume: 19

    Topics: Adamantane; Animals; Antiviral Agents; Chick Embryo; Culture Techniques; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flavonoids; Influenza A virus; Orthomyxoviridae Infections; Phenols; Plants, Medicinal; Polymers; Polyphenols; Rimantadine; Virus Replication

1986
Vaccination as a strategy to reduce the emergence of amantadine- and rimantadine-resistant strains of A/Chick/Pennsylvania/83 (H5N2) influenza virus.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl B

    Topics: Adamantane; Amantadine; Animals; Drug Resistance, Microbial; Influenza A virus; Influenza A Virus, H5N2 Subtype; Influenza Vaccines; Orthomyxoviridae Infections; Poultry; Poultry Diseases; Rimantadine; Vaccination

1986