Compounds > adamantane

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adamantane and Malaria

adamantane has been researched along with Malaria in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (28.57)	29.6817
2010's	9 (64.29)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Beilles, S; Boyd, BJ; Clulow, AJ; Hawley, A; Peng, KY; Ramachandruni, H; Ramirez, G; Salim, M	1
Beilles, S; Boyd, BJ; Clulow, AJ; Hawley, A; Khan, J; Murshed, M; Ramachandruni, H; Ramirez, G; Salim, M	1
Feng, J; Gong, K; McManus, SA; Prud'homme, RK; Ramachandruni, H; Ristroph, KD; White, CE; Zhang, Y	1
Blagborough, AM; Brock, PM; Churcher, TS; Delves, MJ; Gething, PW; Ghani, AC; Leroy, D; Sala, KA; Sinden, RE; Upton, LM	1
Battilocchio, C; Berry, MB; Galván, A; Lau, SH; Ley, SV; Merchant, RR; Souto, JA	1
Barker, H; Bulbule, VJ; Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Dhanasekaran, M; Dong, Y; Hein, CD; Kamaraj, S; Matile, H; Morizzi, J; Papastogiannidis, P; Ryan, E; Scheurer, C; Shackleford, DM; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; White, KL; Wittlin, S; Zhao, Q; Zhou, L	1
Guy, RK; Hammill, JT; Kim, HS	1
Arbe-Barnes, S; Bathurst, IC; Brun, R; Campbell, M; Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Craft, JC; Creek, DJ; Dong, Y; Matile, H; Maurer, M; Morizzi, J; Nguyen, T; Papastogiannidis, P; Scheurer, C; Shackleford, DM; Sriraghavan, K; Stingelin, L; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; White, KL; Wittlin, S; Zhou, L	1
Codd, R; Liao, V; Lifa, T; Liu, J; Obando, D	1
Ackerman, HC; Miller, LH; Su, XZ; Wellems, TE	1
Brun, R; Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Dong, Y; Dorn, A; Karle, JM; Matile, H; Santo Tomas, J; Scheurer, C; Scorneaux, B; Snyder, C; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; Wittlin, S	1
Kanchan, R; Puri, SK; Sharma, U; Singh, C	1
Mishra, D; Rizvi, A; Singh, C; Tripathi, R	1
Chaudhary, S; Puri, SK; Singh, C	1

Reviews

2 review(s) available for adamantane and Malaria

Article	Year
The many faces of the adamantyl group in drug design. European journal of medicinal chemistry, 2011, Volume: 46, Issue:6 Topics: Adamantane; Animals; Antimalarials; Diabetes Mellitus, Type 2; Drug Design; Humans; Hypoglycemic Agents; Iron Chelating Agents; Iron Overload; Malaria; Solubility	2011
Malaria biology and disease pathogenesis: insights for new treatments. Nature medicine, 2013, Volume: 19, Issue:2 Topics: Adamantane; Antimalarials; Drug Discovery; Endothelium, Vascular; Erythrocytes; Humans; Malaria; Membrane Transport Proteins; Merozoites; Nitric Oxide; Peroxides; Protein Kinases; Protozoan Proteins	2013

Other Studies

12 other study(ies) available for adamantane and Malaria

Article	Year
Lipid Compositions in Infant Formulas Affect the Solubilization of Antimalarial Drugs Artefenomel (OZ439) and Ferroquine during Digestion. Molecular pharmaceutics, 2020, 07-06, Volume: 17, Issue:7 Topics: Adamantane; Administration, Oral; Aminoquinolines; Animals; Antimalarials; Chromatography, High Pressure Liquid; Digestion; Excipients; Fatty Acids; Ferrous Compounds; Humans; Infant; Infant Formula; Lipids; Malaria; Mass Spectrometry; Metallocenes; Milk; Peroxides; Scattering, Small Angle; Solubility; Triglycerides	2020
Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria. Molecular pharmaceutics, 2019, 04-01, Volume: 16, Issue:4 Topics: Adamantane; Administration, Oral; Aminoquinolines; Animals; Antimalarials; Biological Availability; Drug Delivery Systems; Ferrous Compounds; Humans; In Vitro Techniques; Lipolysis; Malaria; Metallocenes; Milk; Peroxides; Solubility	2019
Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy. Journal of translational medicine, 2019, 03-22, Volume: 17, Issue:1 Topics: Adamantane; Administration, Oral; Chemistry, Pharmaceutical; Desiccation; Drug Stability; Freeze Drying; Humans; Malaria; Nanoparticles; Nebulizers and Vaporizers; Oral Sprays; Peroxides; Powders; Solubility; Water	2019
Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1 Topics: Adamantane; Animals; Anopheles; Antimalarials; Artemether; Artemisinins; Ethanolamines; Female; Fluorenes; Indoles; Insect Vectors; Lumefantrine; Malaria; Mice; Peroxides; Plasmodium berghei; Primaquine; Spiro Compounds	2015
Machines vs Malaria: A Flow-Based Preparation of the Drug Candidate OZ439. Organic letters, 2015, Jul-02, Volume: 17, Issue:13 Topics: Adamantane; Antimalarials; Malaria; Molecular Structure; Peroxides	2015
Structure-Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439). Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7 Topics: Adamantane; Animals; Antimalarials; Female; Malaria; Male; Mice; Peroxides; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship	2017
Seeking the Elusive Long-Acting Ozonide: Discovery of Artefenomel (OZ439). Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7 Topics: Adamantane; Animals; Antimalarials; Drug Discovery; Humans; Malaria; Peroxides; Plasmodium	2017
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria. Proceedings of the National Academy of Sciences of the United States of America, 2011, Mar-15, Volume: 108, Issue:11 Topics: Adamantane; Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Stability; Heterocyclic Compounds; Iron; Malaria; Male; Mice; Peroxides; Plasmodium berghei; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome	2011
Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Adamantane; Animals; Antimalarials; Cell Line, Tumor; Drug Resistance; Half-Life; Malaria; Malaria, Falciparum; Mice; Micronucleus Tests; Ozone; Peroxides; Plasmodium berghei; Rats; Spiro Compounds; Structure-Activity Relationship	2005
New adamantane-based spiro 1,2,4-trioxanes orally effective against rodent and simian malaria. Journal of medicinal chemistry, 2007, Feb-08, Volume: 50, Issue:3 Topics: Adamantane; Administration, Oral; Animals; Antimalarials; Drug Resistance; Heterocyclic Compounds, 1-Ring; Injections, Intramuscular; Macaca mulatta; Malaria; Mice; Parasitemia; Plasmodium cynomolgi; Plasmodium yoelii; Spiro Compounds; Structure-Activity Relationship	2007
Evaluation of some adamantane-based synthetic trioxanes against Plasmodium knowlesi in rhesus monkeys. Life sciences, 2007, Nov-10, Volume: 81, Issue:21-22 Topics: Adamantane; Animals; Antimalarials; Erythrocytes; Injections, Intramuscular; Macaca mulatta; Malaria; Plasmodium knowlesi; Recurrence	2007
Orally active esters of dihydroartemisinin: Synthesis and antimalarial activity against multidrug-resistant Plasmodium yoelii in mice. Bioorganic & medicinal chemistry letters, 2008, Feb-15, Volume: 18, Issue:4 Topics: Adamantane; Administration, Oral; Animals; Antimalarials; Artemisinins; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Esters; Malaria; Mice; Models, Molecular; Plasmodium yoelii; Sesquiterpenes; Structure-Activity Relationship	2008