adamantane has been researched along with Leukemia in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, LS; Chen, YJ; Wang, JJ | 1 |
| Castro, DJ; Correa, RG; Das, JK; Dawson, MI; Farhana, L; Fontana, JA; Oshima, RG; Reed, JC; Xia, Z; Yu, J | 1 |
| Adjei, AA; Bone, N; Bruzek, LM; Chandra, J; Hackbarth, J; Karp, JE; Kaufmann, SH; Kay, NE; Le, S; Loegering, D; Narayanan, VL; Sausville, EA; Tefferi, A | 1 |
| Almenara, J; Dent, P; Grant, S; Rahmani, M; Sausville, EA; Yu, C | 1 |
| Dasmahapatra, G; Dent, P; Grant, S; Rahmani, M | 1 |
| Beran, M; Bhalla, K; Chandra, J; Donato, N; Estrov, Z; Flatten, K; Gorre, M; Karp, J; Kaufmann, SH; Loegering, D; Sausville, E; Sawyers, C; Talpaz, M; Tracy, J; Verstovsek, S | 1 |
6 other study(ies) available for adamantane and Leukemia
| Article | Year |
|---|---|
Naja nigricollis CMS-9 enhances the mitochondria-mediated death pathway in adaphostin-treated human leukaemia U937 cells.
Topics: Adamantane; Animals; Apoptosis; Apoptosis Regulatory Proteins; Calcium; Cell Death; Cell Survival; Elapid Venoms; Extracellular Signal-Regulated MAP Kinases; Humans; Hydroquinones; K562 Cells; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; p38 Mitogen-Activated Protein Kinases; Phospholipases A2; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tumor Cells, Cultured; U937 Cells | 2011 |
Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apoptosis of
Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cinnamates; Drug Screening Assays, Antitumor; Leukemia; Ligands; Mice; Models, Molecular; Neoplastic Stem Cells; Receptors, Cytoplasmic and Nuclear; Stem Cells; Stereoisomerism; Structure-Activity Relationship; Wnt1 Protein | 2012 |
Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells.
Topics: Acetylcysteine; Adamantane; Antioxidants; Apoptosis; Buthionine Sulfoximine; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Glutathione; Humans; Hydroquinones; K562 Cells; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Quinones; Reactive Oxygen Species; Tumor Stem Cell Assay; Tyrphostins | 2003 |
Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process.
Topics: Adamantane; Apoptosis; Apoptosis Inducing Factor; Cytochromes c; Flavoproteins; Humans; Hydroquinones; Jurkat Cells; Leukemia; MAP Kinase Kinase Kinases; Membrane Proteins; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf | 2004 |
The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism.
Topics: Adamantane; Apoptosis; Cell Line, Tumor; Drug Synergism; Enzyme Inhibitors; Humans; Hydroquinones; Jurkat Cells; Leukemia; Oxidative Stress; Proteasome Inhibitors; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured; Tyrphostins | 2006 |
Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance.
Topics: Adamantane; Apoptosis; Benzamides; Cell Line, Tumor; Clone Cells; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Hydroquinones; Imatinib Mesylate; Leukemia; Mutation; Oxidative Stress; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Reactive Oxygen Species | 2006 |