adamantane has been researched along with Innate Inflammatory Response in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 25 (75.76) | 24.3611 |
| 2020's | 5 (15.15) | 2.80 |
| Authors | Studies |
|---|---|
| El-Naga, RN; Gad, AM; Nazeem, M; Wahdan, SA | 1 |
| Ali Shah, SJ; Iqbal, J; Mahmood, A | 1 |
| Dudka, J; Gawrońska-Grzywacz, M; Herbet, M; Piątkowska-Chmiel, I; Popiołek, Ł | 1 |
| Chen, Q; Gao, C; Kwong, CHT; Lee, SMY; Liu, C; Wang, Q; Wang, R; Wang, Y; Xie, B | 1 |
| Fearon, U; Flynn, K; Hanlon, MM; Marzaioli, V; O'Brien, A; Veale, DJ; Wade, SC | 1 |
| Cheng, F; Guo, X; He, J; Yuan, G; Zhang, J | 1 |
| Aroor, AR; Bender, SB; Brown, SM; Chandrasekar, B; Cleeton, HM; DeMarco, VG; Khan, M; Meininger, GA; Meuth, AI; Nistala, R; Smith, CE; Sowers, JR | 1 |
| Apaijai, N; Chattipakorn, N; Chattipakorn, S; Ittichaicharoen, J; Sa-Nguanmoo, P; Tanajak, P | 1 |
| Dong, Z; Yuan, Y | 1 |
| Jian, Q; Jiang, J; Jing, M; Shan, L; Wang, Y; Xu, L; Yu, P; Zhang, G; Zhang, Z | 1 |
| Abudayyak, M; Celiksoz, M; Özhan, G; Oztas, E | 1 |
| D'Souza, K; Koska, J; Meyer, C; Osredkar, T; Reaven, PD; Sands, M; Sinha, S; Zhang, W | 1 |
| Chen, J; Guo, X | 1 |
| Araki, E; Goto, R; Igata, M; Kawasaki, S; Kawashima, J; Kitano, S; Kondo, T; Matsumura, T; Matsuyama, R; Miyagawa, K; Motoshima, H; Ono, K | 1 |
| Baek, KS; Beak, HS; Cho, JY; Choi, J; Ha, VT; Hong, S; Hossen, MJ; Joo, YH; Kim, E; Kim, JH; Kim, Y; Lee, CS; Shin, HJ; Shin, SS; Yang, S; Yang, WS | 1 |
| Ametamey, SM; Bieri, D; Herde, AM; Krämer, SD; Mu, L; Schibli, R; Slavik, R; Weber, M | 1 |
| Alam, MM; Jang, JH; Kang, DG; Kim, YC; Koh, YS; Lee, DH; Lee, DS; Lee, ES; Lee, HS; Manzoor, Z; Oh, H | 1 |
| Hayami, N; Iwasaki, YK; Murakawa, Y; Sekiguchi, A; Yamashita, T | 1 |
| El Sarha, A; Refaat, R; Sakr, A; Salama, M | 1 |
| Bradshaw, E; Broom, DC; Buck, ME; Coombs, S; Cortright, DN; Ford, KK; Krause, JE; Matchett, M; Matson, DJ; Meade, R; Ochoa, R; Sun, SH; Wustrow, DJ; Yu, W; Yuan, J | 1 |
| Aerts, JM; Arbeeny, C; Aten, J; Bijl, N; Dubbelhuis, PF; Ghauharali-van der Vlugt, K; Groen, AK; Ottenhoff, R; Overkleeft, HS; Seeman, I; van Eijk, M; van Roomen, CP | 1 |
| Ciccarelli, L; D'Angelo, A; Derosa, G; Ferrari, I; Franzetti, IG; Gadaleta, G; Maffioli, P; Mereu, R; Piccinni, MN; Querci, F; Ragonesi, PD; Salvadeo, SA | 1 |
| Donahue, H; Fitzpatrick, LR; Frauenhoffer, EE; French, KJ; Green, C; Maines, LW; Mosher, TJ; Paul, E; Smith, CD; Upson, JJ; Zhuang, Y | 1 |
| Krishnasamy, Y; Lemasters, JJ; Liu, Q; Ramshesh, VK; Rehman, H; Schwartz, J; Shi, Y; Smith, CD; Zhang, X; Zhong, Z | 1 |
| Durnev, AD; Kovalenko, LP; Seredenin, SB; Tallerova, AV | 1 |
| Cao, F; Li, W; Liu, B; Shen, M; Sun, D; Wang, S; Zhang, Z | 1 |
| Fisman, EZ; Goldenberg, I; Klempfner, R; Leor, J; Tenenbaum, A | 1 |
| Barbieri, M; Marfella, R; Paolisso, G; Rizzo, MR | 1 |
| Akarte, AS; Gandhi, S; Sole, S; Srinivasan, BP | 1 |
| Krishnasamy, Y; Lemasters, JJ; Liu, Q; Rehman, H; Shi, Y; Smith, CD; Zhong, Z | 1 |
| Oates, JC; Obeid, LM; Ruiz, P; Snider, AJ | 1 |
| Barbieri, M; Boccardi, V; Esposito, A; Marfella, R; Pansini, A; Paolisso, G; Rizzo, MR | 1 |
| Eiserich, JP; Hammock, BD; Kim, IH; Kubala, L; Newman, JW; Schmelzer, KR | 1 |
5 trial(s) available for adamantane and Innate Inflammatory Response
| Article | Year |
|---|---|
Effects of saxagliptin on adipose tissue inflammation and vascular function in overweight and obese people: a placebo-controlled study.
Topics: Adamantane; Adipose Tissue; Adult; Aged; Blood Glucose; Cells, Cultured; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Endothelial Cells; Endothelium, Vascular; Female; Glycated Hemoglobin; Humans; Immunohistochemistry; Inflammation; Male; Middle Aged; Obesity; Overweight; Postprandial Period; Treatment Outcome | 2019 |
Effects of one year treatment of vildagliptin added to pioglitazone or glimepiride in poorly controlled type 2 diabetic patients.
Topics: Adamantane; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Inflammation; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Nitriles; Pioglitazone; Pyrrolidines; Sulfonylurea Compounds; Thiazolidinediones; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Vildagliptin | 2010 |
Effects of a vildagliptin/metformin combination on markers of atherosclerosis, thrombosis, and inflammation in diabetic patients with coronary artery disease.
Topics: Adamantane; Adiponectin; Atherosclerosis; Biomarkers; C-Reactive Protein; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Humans; Hypoglycemic Agents; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Israel; Matrix Metalloproteinase 9; Metformin; Nitriles; Platelet Function Tests; Prospective Studies; Pyrrolidines; Research Design; Thrombosis; Time Factors; Treatment Outcome; Vildagliptin | 2012 |
Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition.
Topics: Adamantane; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Glycated Hemoglobin; Humans; Inflammation; Interleukin-18; Interleukin-6; Male; Metformin; Middle Aged; Nitriles; Oxidative Stress; Postprandial Period; Prospective Studies; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin | 2012 |
Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors.
Topics: Adamantane; Atherosclerosis; Blood Glucose; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cytokines; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glycated Hemoglobin; Humans; Inflammation; Nitriles; Oxidative Stress; Prospective Studies; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Tyrosine; Vildagliptin | 2013 |
28 other study(ies) available for adamantane and Innate Inflammatory Response
| Article | Year |
|---|---|
Saxagliptin ameliorated the depressive-like behavior induced by chronic unpredictable mild stress in rats: Impact on incretins and AKT/PI3K pathway.
Topics: Adamantane; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain; Brain-Derived Neurotrophic Factor; Caspase 3; Depression; Dipeptides; Disease Models, Animal; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Incretins; Inflammation; Male; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Stress, Psychological | 2021 |
Design and synthesis of adamantane-1-carbonyl thiourea derivatives as potent and selective inhibitors of h-P2X4 and h-P2X7 receptors: An Emerging therapeutic tool for treatment of inflammation and neurological disorders.
Topics: Adamantane; Humans; Inflammation; Nervous System Diseases; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; Thiourea | 2022 |
The novel adamantane derivatives as potential mediators of inflammation and neural plasticity in diabetes mice with cognitive impairment.
Topics: Adamantane; Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Dopamine Agents; Humans; Inflammation; Inflammation Mediators; Mice; Neuronal Plasticity | 2022 |
Cyclodextrin-mediated conjugation of macrophage and liposomes for treatment of atherosclerosis.
Topics: Adamantane; Animals; Atherosclerosis; beta-Cyclodextrins; Cholesterol; Cyclodextrins; Humans; Inflammation; Liposomes; Liver X Receptors; Macrophages; Mice; NF-E2-Related Factor 2; Plaque, Atherosclerotic; Quercetin | 2022 |
Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function.
Topics: Adamantane; Adult; Aged; Arthritis, Psoriatic; Azetidines; Cells, Cultured; Female; Fibroblasts; Heterocyclic Compounds, 3-Ring; Humans; Inflammation; Janus Kinase Inhibitors; Janus Kinases; Male; Middle Aged; Niacinamide; Purines; Pyrazoles; Pyridines; Signal Transduction; STAT Transcription Factors; Sulfonamides; Synovial Membrane; Triazoles | 2021 |
Mast Cell and M1 Macrophage Infiltration and Local Pro-Inflammatory Factors Were Attenuated with Incretin-Based Therapies in Obesity-Related Glomerulopathy.
Topics: Adamantane; Albuminuria; Animals; Creatinine; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Glucose Tolerance Test; Incretins; Inflammation; Interleukin-6; Kidney Diseases; Kidney Glomerulus; Liraglutide; Macrophages; Male; Mast Cells; Nitriles; Obesity; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vildagliptin | 2017 |
Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II-Induced Cardiac Diastolic Dysfunction in Male Mice.
Topics: Adamantane; Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; CD4-Positive T-Lymphocytes; CD8 Antigens; Diastole; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Echocardiography; Fibrosis; Gene Expression; Heart; Inflammation; Interleukin-17; Interleukin-18; Lymphocytes; Macrophages; Male; Mice; Proto-Oncogene Proteins c-jun; Signal Transduction; Vascular Stiffness; Vasoconstrictor Agents | 2017 |
Dipeptidyl peptidase-4 inhibitor enhances restoration of salivary glands impaired by obese-insulin resistance.
Topics: Adamantane; Animals; Apoptosis; Blotting, Western; Diet, High-Fat; Dipeptidyl-Peptidase IV Inhibitors; Inflammation; Insulin Resistance; Male; Mitochondria; Nitriles; Obesity; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Salivary Glands; Vildagliptin | 2018 |
Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: Ιnhibition by ST1926.
Topics: Acute Lung Injury; Adamantane; Animals; Cell Line; Cinnamates; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Oxidative Stress | 2018 |
The novel N-methyl-d-aspartate receptor antagonist MN-08 ameliorates lipopolysaccharide-induced acute lung injury in mice.
Topics: A549 Cells; Acute Lung Injury; Adamantane; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Humans; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; RAW 264.7 Cells; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tight Junctions; Tumor Necrosis Factor-alpha | 2019 |
Inflammation and oxidative stress are key mediators in AKB48-induced neurotoxicity in vitro.
Topics: Adamantane; Cannabinoids; Cell Line, Tumor; Humans; Indazoles; Inflammation; Interleukin-6; Mitogen-Activated Protein Kinase 8; Neurotoxicity Syndromes; Oxidative Stress; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2019 |
The protective effects of saxagliptin against lipopolysaccharide (LPS)-induced inflammation and damage in human dental pulp cells.
Topics: Adamantane; Cytoprotection; Dental Pulp; Dipeptides; Dose-Response Relationship, Drug; Humans; Inflammation; Lipopolysaccharides; Mitochondria | 2019 |
Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.
Topics: Adamantane; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Homeodomain Proteins; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Nitriles; Phlorhizin; Pyrrolidines; Tetrazoles; Trans-Activators; Valine; Valsartan; Vildagliptin | 2013 |
NF-κB/AP-1-targeted inhibition of macrophage-mediated inflammatory responses by depigmenting compound AP736 derived from natural 1,3-diphenylpropane skeleton.
Topics: Adamantane; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Cell Line; Gene Expression; HEK293 Cells; Humans; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Melanins; Mice; Molecular Structure; NF-kappa B; Nitric Oxide Synthase Type II; Signal Transduction; Skin; Skin Pigmentation; Transcription Factor AP-1 | 2014 |
Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor.
Topics: Adamantane; Animals; Autoradiography; Carbon Radioisotopes; Disease Models, Animal; Humans; Inflammation; Male; Mice; Molecular Imaging; Molecular Structure; Nervous System Diseases; Positron-Emission Tomography; Quinolones; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Tissue Distribution | 2015 |
Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate.
Topics: Adamantane; Animals; Cells, Cultured; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Inflammation; Lipopolysaccharides; Mannosephosphates; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Nitriles; Pyrrolidines; RNA, Messenger; Toll-Like Receptors; Vildagliptin | 2016 |
No Additional Effect of DPP-4 Inhibitor on Preventing Atrial Fibrosis in Streptozotocin-Induced Diabetic Rat as Compared With Sulfonylurea.
Topics: Adamantane; Animals; Anti-Inflammatory Agents; Atrial Fibrillation; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Endomyocardial Fibrosis; Female; Glyburide; Heart Atria; Hypoglycemic Agents; Immunohistochemistry; Inflammation; Nitriles; Pyrrolidines; Rats; Rats, Wistar; Statistics as Topic | 2016 |
Combination of Vildagliptin and Pioglitazone in Experimental Type 2 Diabetes in Male Rats.
Topics: Adamantane; Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Hypoglycemic Agents; Inflammation; Insulin; Kidney; Liver; Male; Nitriles; Oxidative Stress; Pancreas; Pioglitazone; Pyrrolidines; Rats; Rats, Wistar; Thiazolidinediones; Urea; Vildagliptin | 2016 |
Characterization of N-(adamantan-1-ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation.
Topics: Adamantane; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzamides; Benzoxazoles; Calcium; Disease Models, Animal; Humans; Inflammation; Inhibitory Concentration 50; Pain; Purinergic P2 Receptor Antagonists; Quinolinium Compounds; Rats; Receptors, Purinergic P2X7 | 2008 |
Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
Topics: 1-Deoxynojirimycin; Adamantane; Adipogenesis; Adiponectin; Adipose Tissue; Animals; Chemokine CCL2; Glucose; Glycosphingolipids; Homeostasis; Inflammation; Insulin Resistance; Macrophages; Mice; Mice, Inbred C57BL; Mice, Obese; Signal Transduction | 2009 |
Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase.
Topics: Adamantane; Administration, Oral; Animals; Ankle; Ankle Joint; Arthritis, Experimental; Body Weight; Drug Therapy, Combination; Edema; Enzyme Inhibitors; Female; Foot; Indomethacin; Inflammation; Methotrexate; Mice; Mice, Inbred DBA; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Rats; Rats, Inbred Lew; Splenomegaly; X-Ray Microtomography | 2011 |
Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion.
Topics: Adamantane; Animals; Cell Death; Enzyme Inhibitors; Gene Knockdown Techniques; Hepatocytes; In Vitro Techniques; Inflammation; Liver; Lysophospholipids; Male; Mice; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitric Oxide Synthase Type II; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Reperfusion Injury; RNA, Messenger; RNA, Small Interfering; Sphingosine | 2012 |
[Effect of antiasthenic drug ladasten on the level of cytokines and behavior in experimental model of anxious depression in C57BL/6 male mice].
Topics: Adamantane; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Depression; Disease Models, Animal; Imipramine; Inflammation; Injections, Intraperitoneal; Interleukin-17; Interleukin-4; Interleukin-6; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Organ Size; Spleen; Stress, Psychological; Thymus Gland | 2011 |
The synergistic effect of valsartan and LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] on vascular oxidative stress and inflammation in type 2 diabetic mice.
Topics: Adamantane; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Apoptosis; Blood Glucose; Diabetes Mellitus, Type 2; Drug Synergism; Endothelial Cells; Endothelium, Vascular; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Hypoglycemic Agents; Inflammation; Intercellular Adhesion Molecule-1; Mice; NADPH Oxidases; Oxidative Stress; Pyrrolidines; Receptors, Glucagon; Tetrazoles; Valine; Valsartan; Vascular Cell Adhesion Molecule-1 | 2012 |
Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.
Topics: Adamantane; Animals; Blood Glucose; Blood Proteins; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Gene Expression Regulation; Glucagon-Like Peptide 1; Glucose Transporter Type 2; Glucose Transporter Type 4; Glycogen; Hypoglycemic Agents; Inflammation; Insulin; Insulin Secretion; Liver; Muscle, Skeletal; Nitrates; Nitriles; Nitrites; Pancreas; Pyrrolidines; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha | 2012 |
Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats.
Topics: Adamantane; Animals; Cell Adhesion Molecules; Chemokines; Enzyme Inhibitors; Inflammation; Leukocytes; Liver; Liver Transplantation; Lysophospholipids; Male; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Rats; Rats, Inbred Lew; Reactive Oxygen Species; Reperfusion Injury; Sphingosine; Toll-Like Receptor 4; Up-Regulation | 2012 |
Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis.
Topics: Adamantane; Albumins; Animals; Cell Separation; Disease Models, Animal; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation, Enzymologic; Inflammation; Isoenzymes; Kidney Glomerulus; Lupus Nephritis; Mice; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Sphingolipids; Spleen; Thromboxane B2 | 2013 |
Soluble epoxide hydrolase is a therapeutic target for acute inflammation.
Topics: Adamantane; Animals; Arachidonic Acids; Blood Pressure; Chromatography, High Pressure Liquid; Cytokines; Dose-Response Relationship, Drug; Epoxide Hydrolases; Immunoblotting; Inflammation; Lipopolysaccharides; Lipoxins; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Prostaglandin-Endoperoxide Synthases; Urea | 2005 |