adamantane has been researched along with Grippe in 104 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (34.62) | 18.7374 |
1990's | 2 (1.92) | 18.2507 |
2000's | 34 (32.69) | 29.6817 |
2010's | 28 (26.92) | 24.3611 |
2020's | 4 (3.85) | 2.80 |
Authors | Studies |
---|---|
Caffrey, M; Degrado, WF; Kolocouris, A; Konstantinidi, A; Lambrinidis, G; Liu, L; Tan, J; Thomaston, JL; Wang, J | 1 |
Deryabin, PG; Finogenova, MP; Garaev, TM; Odnovorov, AI | 1 |
Duncan, MC; Fedida, D; Jalily, PH; Tietjen, I; Wang, J | 1 |
DeGrado, WF; Voth, GA; Watkins, LC | 1 |
Dong, G; He, W; Wang, C; Wu, Q; Xie, Y; Xu, H; Yan, H; Zhang, W | 1 |
Barr, I; Deng, YM; Hurt, A; Kaye, M; Komadina, N; Subbarao, K; Sullivan, S | 1 |
Acosta, B; Arencibia, A; González, G; Goyenechea, A; Hernández, B; Muné, M; Oropesa, S; Pérez, A; Piñón, A; Savón, C; Valdés, O | 1 |
Aris-Brosou, S; Garcia, V | 1 |
Chun, K; Lessler, J; Rainwater-Lovett, K | 1 |
Hurt, AC | 1 |
Dong, G; Han, L; He, H; Ji, G; Luo, J; Peng, C; Wang, C; Wu, B | 1 |
Beggs, NF; Dobrovolny, HM | 1 |
Korabecny, J; Kuca, K; Nepovimova, E; Soukup, O; Spilovska, K; Windisch, M; Zemek, F | 1 |
DeGrado, WF; Hu, Y; Ma, C; Musharrafieh, R; Smee, DF; Wang, J; Zhang, J | 1 |
Barr, IG; Deng, YM; Hurt, AC; Iannello, P; Komadina, N | 1 |
Cohen, NJ; Gerber, SI; Jones, RC; Morita, JY; Nawrocki, J; Plate, DK; Simon, MT; Siston, AM | 1 |
Guralnick, RP; Habib, F; Hill, AW; Janies, D; Wilson, MJ | 1 |
Cristina, J; Goñi, N; Russi, J | 1 |
Laplante, JM; Marshall, SA; Mingle, LA; Reisdorf, ES; Shudt, M; Shult, PA; St George, K; Van, TT | 1 |
Jacobson, RM; Ovsyannikova, IG; Poland, GA | 1 |
Holmes, EC; Miller, MA; Nelson, MI; Simonsen, L; Viboud, C | 1 |
Huang, LM; Shao, PL | 1 |
Cilla, G; Mendiola, J; Montes, M; Pérez-Trallero, E; Vicente, D | 1 |
Hannongbua, S; Intharathep, P; Kaiyawet, N; Malaisree, M; Nunthaboot, N; Payungporn, S; Poovorawan, Y; Rungrotmongkol, T; Sompornpisut, P | 1 |
Agudo, R; Barrantes, M; Comach, G; de Rivera, I; Douce, R; García, J; Gomez, J; Jimenez, M; Kochel, T; Sanchez, F; Sovero, M; Torres, AL | 1 |
Raguram, S; Raman, R; Sasisekharan, R; Sasisekharan, V; Shriver, Z; Soundararajan, V; Tharakaraman, K | 1 |
Dijkstra, F; Jonges, M; Koopmans, M; Meijer, A; van der Lubben, IM; Verhoef, L | 1 |
Barnes, J; Deyde, V; Garten, R; Gubareva, L; Klimov, A; Myrick, A; Shaw, M; Sheu, T; Smith, C; Xu, X | 1 |
Abughali, N; Abzug, MJ; Bradley, JS; Cloud, GA; Englund, J; Griffin, J; Guzman-Cottrill, J; Jacobs, RF; Jester, P; Kimberlin, DW; Lang, D; Leach, C; Ramilo, O; Robinson, J; Romero, JR; Shalabi, M; Shelton, M; Storch, G; Wade, KC; Whitley, RJ | 1 |
Chen, KF; Gaydos, CA; Hsieh, YH; Kelen, GD; Rothman, RE | 1 |
Antón, A; de Anta, MT; de Molina, P; Isanta, R; Marcos, MA; Martínez, MJ; Pumarola, T; Ramón, S | 1 |
Barontini, M; Crucianelli, M; Nencioni, L; Palamara, AT; Saladino, R; Sgarbanti, R | 1 |
Arkin, IT; Astrahan, P | 1 |
Beekmann, SE; Dharan, NJ; Finelli, L; Fiore, A; Fry, AM; Polgreen, PM; Uyeki, TM | 1 |
Gums, JG; Smith, SM | 1 |
Basler, CF; Fytas, C; Fytas, G; Kolocouris, A; Valmas, C; Zoidis, G | 1 |
Ison, MG; Lee, N | 1 |
de Jong, MD; Hayden, FG | 1 |
Bullion, L; Deyde, VM; Fry, AM; Garten, RJ; Gubareva, LV; Klimov, AI; Li, Y; Peebles, PJ; Sheu, TG; Shwe, T | 1 |
Deyde, VM; Fry, AM; Garten, RJ; Gubareva, LV; Klimov, AI; Mishin, VP; Nguyen, HT; Okomo-Adhiambo, M; Shaw, MW; Sheu, TG; Sleeman, K; Trujillo, AA | 1 |
Alcantara-Perez, P; Alpuche-Aranda, C; Barrera-Badillo, G; Cordova Villalobos, JA; Cortez-Ortiz, I; Díaz-Quiñonez, JA; Gatell-Ramírez, HL; Gonzalez-Duran, E; Gubareva, L; Hernández-Avila, M; Lezana-Fernández, MA; Lopez-Martinez, I; Nguyen, H; Olivera-Diaz, H; Ramirez-Gonzalez, JE; Wong-Arambula, C | 1 |
Hou, N; Jonges, M; Ke, C; Koopmans, M; Li, H; Liao, J; Meijer, A; Ni, H; Wang, Y; Wu, J; Zhang, X; Zhou, J; Zou, L | 1 |
Rohde, GG | 1 |
Bonovas, S; Nikolopoulos, G; Tsiodras, S | 1 |
Boucher, CA; Collins, PJ; Gamblin, SJ; Haire, LF; Hay, AJ; Liu, J; Martin, SR; Osterhaus, AD; Schutten, M; Skehel, JJ; Vachieri, SG; van der Vries, E; Walker, PA; Xiong, X | 1 |
De Clercq, E; Foscolos, GB; Fytas, G; Kolocouris, A; Kolocouris, N; Neyts, J; Padalko, E; Stylianakis, I | 1 |
Lu, Q | 1 |
Moscona, A | 1 |
Chen, H; Guan, Y | 1 |
Bright, RA; Cox, NJ; Klimov, AI; Shay, DK; Shu, B | 1 |
Weinstock, DM; Zuccotti, G | 1 |
Linder, JA | 1 |
Barr, IG; Deed, N; Hurt, AC; Iannello, P; Komadina, N; Tomasov, C | 2 |
Shah, RC | 1 |
Shea, KM | 1 |
Amicizia, D; Ansaldi, F; Banfi, F; Crovari, P; Gasparini, R; Icardi, G; Pastorino, B; Sticchi, L; Valle, L | 1 |
Barr, I; Ho, HT; Hurt, AC | 1 |
Dushoff, J; Gog, J; Grenfell, BT; Hata, M; Holmes, EC; Jennings, L; Macken, C; Miller, MA; Simonsen, L; Smit, M; Viboud, C | 1 |
Campbell, JD | 1 |
Balish, A; Belongia, EA; Bright, RA; Cox, NJ; Donahue, JG; Foust, A; Greenlee, RT; Kieke, BA; Klimov, AI; Rahman, M; Shay, DK; Vandermause, M | 1 |
Fonseca, K; Fox, JD; Ho, KC; Pabbaraju, K; Pang, XL; Shokoples, S; Wong, S | 1 |
Chan, PK; Lam, WY; Ngai, KL; Tang, JW; Wong, JC | 1 |
Efremov, BV; Erofeeva, MK; Ignat'eva, GS; Maksakova, VL; Malysheva, AM | 1 |
Araslanova, II; Gagarinova, VM; Kubar', OI; Kustikova, IuG; Shadrin, AS | 1 |
Bigimbetova, ShSh; Smagulov, KZ; Smagulova, EG | 1 |
Gorenskaia, RL; Kubar', OI; Leonov, VM; Romanov, IuA; Rumel', NB | 1 |
Gorenskaia, RA; Kubar', OI; Padalko, IuV; Reĭkh, LIa; Romanov, IuA | 1 |
Kubar', OI; Romanov, IuA; Rumen', NB; Vasilevskaia, NM; Zherbina, LA | 1 |
Bregman, DJ; Kater, NA; Kendal, AP; Patriarca, PA; Sikes, RK; Smith, JD | 1 |
Erofeeva, MK; Shadrin, AS | 1 |
Sebastiani, A | 1 |
Dolin, R; Linton, PN; Madore, HP; Maynard, R; Reichman, RC; Webber-Jones, J | 1 |
Hayden, FG; Iljenko, VI; Padolka, YV; Zylidnikov, DM | 1 |
Erofeeva, MK; Lugovskaia, VP; Malysheva, AM; Oleĭnikova, EV; Shadrin, AS | 1 |
Geĭker, VI; Romanov, IuA; Rumel', NB; Vasilevskaia, NM; Zlydnikov, DM | 1 |
Zlydnikov, DM | 3 |
Cate, TR; Couch, RB; Goswick, CB; Quarles, JM | 1 |
Hayden, FG; Kaiser, L | 1 |
Krylov, VF | 1 |
Eggers, HJ | 1 |
Galasso, GJ; LaMontagne, JR | 1 |
Alekseeva, AA; Demidova, SA; Krylov, VF; Kuptsevich, TP; Smagulova, EG | 1 |
Oxford, JS | 1 |
Arroyo, M; Beare, AS; Craig, JW; Reed, SE | 1 |
Boissel, JP; Bricaire, F; Hannoun, C | 1 |
Belshe, RB; Clover, RD; Hay, AJ; Hayden, FG; Oakes, MG; Soo, W | 1 |
Betts, RF | 1 |
Bentley, DW; Betts, RF; Karki, SD | 1 |
Belshe, RB; Burk, B; Cerruti, RL; Newman, F; Sim, IS | 1 |
Kubar', OI; Shvetsova, EG; Zlydnikov, DM | 1 |
Belshe, RB; Betts, R; Hall, CB; Hay, AJ; Smith, MH | 1 |
Abell, TD; Clover, RD; Couch, RB; Crawford, SA; Glezen, P; Ramsey, CN | 1 |
Disney, FA; Dolin, R; Francis, AB; Gala, CL; Green, JL; Hall, CB; Madore, PH; Markovitz, DM; Talpey, WB; Zhang, YQ | 1 |
Hayden, FG; Tominack, RL | 1 |
Abell, TD; Clover, RD; Couch, RB; Crawford, SA; Glezen, WP; Ramsey, CN | 1 |
Hayden, FG; Monto, AS | 1 |
Fleet, W; Lawrence, E; Morris, L; Pierce, E; Thompson, J; Wright, P | 1 |
16 review(s) available for adamantane and Grippe
Article | Year |
---|---|
Put a cork in it: Plugging the M2 viral ion channel to sink influenza.
Topics: Adamantane; Animals; Antiviral Agents; Drug Development; Drug Discovery; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Ion Channels; Orthomyxoviridae Infections; Viral Matrix Proteins; Virus Replication | 2020 |
Influenza outbreak control practices and the effectiveness of interventions in long-term care facilities: a systematic review.
Topics: Adamantane; Aged; Antiviral Agents; Chemoprevention; Disease Outbreaks; Health Facilities; Humans; Infection Control; Influenza, Human; Long-Term Care; Masks | 2014 |
The epidemiology and spread of drug resistant human influenza viruses.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Mutation, Missense; Neuraminidase; Oseltamivir; Viral Proteins; Virulence | 2014 |
Adamantane - A Lead Structure for Drugs in Clinical Practice.
Topics: Adamantane; Alzheimer Disease; Antiviral Agents; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Influenza, Human | 2016 |
Current advances in anti-influenza therapy.
Topics: Adamantane; Antiviral Agents; Cyclohexenes; Cyclopentanes; Flavonoids; Glutathione; Heterocyclic Compounds; Humans; Influenza, Human; Orthomyxoviridae; Phenols; Polyphenols | 2010 |
Resistance characteristics of influenza to amino-adamantyls.
Topics: Adamantane; Amantadine; Amino Acid Sequence; Drug Resistance, Viral; Genes, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Ion Channels; Models, Molecular; Molecular Sequence Data; Mutation; Protein Stability; Protein Structure, Tertiary; Rimantadine; Sequence Homology, Amino Acid; Viral Matrix Proteins | 2011 |
Antivirals for influenza: strategies for use in pediatrics.
Topics: Adamantane; Animals; Antiviral Agents; Child; Drug Therapy, Combination; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Pediatrics | 2010 |
Influenza 2010-2011: lessons from the 2009 pandemic.
Topics: Adamantane; Antiviral Agents; Diagnostic Tests, Routine; Disease Outbreaks; Drug Resistance; Global Health; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Risk Factors; Seasons | 2010 |
Antivirals used for influenza chemoprophylaxis.
Topics: Adamantane; Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae | 2012 |
Neuraminidase inhibitors for influenza.
Topics: Acetamides; Adamantane; Adult; Aged; Antiviral Agents; Child; Disease Outbreaks; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2005 |
Resistance to anti-influenza drugs: adamantanes and neuraminidase inhibitors.
Topics: Adamantane; Animals; Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase | 2006 |
Antiviral therapy and prophylaxis for influenza in children.
Topics: Adamantane; Amantadine; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Influenza, Human; Male; Oseltamivir; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Rimantadine; Risk Assessment; Severity of Illness Index; Treatment Outcome; Zanamivir | 2007 |
Hospitalizing influenza in adults.
Topics: Adamantane; Adult; Antiviral Agents; Enzyme Inhibitors; Female; Hospitalization; Humans; Immunocompromised Host; Influenza, Human; Male; Neuraminidase; Pneumonia, Viral | 1999 |
Specific inhibitors of influenza virus replication as potential chemoprophylactic agents.
Topics: Adamantane; Amantadine; Animals; Antiviral Agents; DNA-Directed RNA Polymerases; Drug Resistance, Microbial; Humans; Influenza, Human; Models, Molecular; Orthomyxoviridae; Ribavirin; Virus Replication | 1975 |
Amantadine and rimantadine for the prevention of influenza A.
Topics: Adamantane; Adult; Age Factors; Aged; Amantadine; Child; Humans; Influenza A virus; Influenza, Human; Rimantadine; Seasons; United States | 1989 |
Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections.
Topics: Adamantane; Adult; Aged; Amantadine; Humans; Influenza A virus; Influenza, Human; Rimantadine | 1987 |
15 trial(s) available for adamantane and Grippe
Article | Year |
---|---|
[Evaluation of rimantadine effectiveness during influenza A2-Texas epidemic in 1979-1980].
Topics: Adamantane; Clinical Trials as Topic; Disease Outbreaks; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Influenza A virus; Influenza, Human; Rimantadine; Russia | 1981 |
Safety of prolonged administration of rimantadine hydrochloride in the prophylaxis of influenza A virus infections in nursing homes.
Topics: Adamantane; Cross Infection; Humans; Influenza A virus; Influenza, Human; Nursing Homes; Rimantadine; Time Factors | 1984 |
A controlled trial of amantadine and rimantadine in the prophylaxis of influenza A infection.
Topics: Adamantane; Adolescent; Adult; Amantadine; Clinical Trials as Topic; Humans; Infant, Newborn; Influenza A virus; Influenza, Human; Middle Aged; Patient Compliance; Random Allocation; Rimantadine | 1982 |
Comparative therapeutic effect of aerosolized and oral rimantadine HCl in experimental human influenza A virus infection.
Topics: Adamantane; Administration, Oral; Aerosols; Female; Fever; Humans; Influenza, Human; Male; Rimantadine | 1982 |
From the National Institutes of Health. Report of a workshop on clinical studies of the efficacy of amantadine and rimantadine against influenza vireus.
Topics: Adamantane; Amantadine; Bridged-Ring Compounds; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Humans; In Vitro Techniques; Influenza, Human; Michigan; National Institutes of Health (U.S.); Orthomyxoviridae; Placebos; United States | 1978 |
[Use of rimantadine for the treatment and prevention of influenza in the polyclinic].
Topics: Adamantane; Bridged-Ring Compounds; Clinical Trials as Topic; Drug Evaluation; Humans; Influenza, Human; Moscow; Time Factors | 1979 |
A therapeutic study of an adamantane spiro compound in experimental influenza A infection in man.
Topics: Adamantane; Adolescent; Adult; Bridged-Ring Compounds; Clinical Trials as Topic; Female; Humans; Influenza A virus; Influenza, Human; Male; Middle Aged; Placebos; Spiro Compounds; Time Factors | 1975 |
[Prevention of influenza A. Effectiveness and tolerance of rimantadine hydrochloride].
Topics: Adamantane; Clinical Trials as Topic; Drug Evaluation; Female; France; Humans; Influenza A virus; Influenza, Human; Male; Placebos; Premedication; Rimantadine | 1990 |
Emergence and apparent transmission of rimantadine-resistant influenza A virus in families.
Topics: Adamantane; Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Resistance, Microbial; Female; Humans; Infant; Influenza A virus; Influenza, Human; Male; Middle Aged; Random Allocation; Rimantadine | 1989 |
Genetic basis of resistance to rimantadine emerging during treatment of influenza virus infection.
Topics: Adamantane; Amino Acid Sequence; Base Sequence; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Influenza A virus; Influenza, Human; Molecular Sequence Data; Rimantadine | 1988 |
Rimantadine prophylaxis in children: a follow-up study.
Topics: Adamantane; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Follow-Up Studies; Humans; Infant; Influenza, Human; Lung Diseases, Obstructive; Rimantadine; Risk Factors | 1988 |
Children with influenza A infection: treatment with rimantadine.
Topics: Acetaminophen; Adamantane; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Influenza, Human; Male; Random Allocation; Rimantadine | 1987 |
Effectiveness of rimantadine prophylaxis of children within families.
Topics: Adamantane; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Influenza A virus; Influenza B virus; Influenza, Human; Male; Office Visits; Patient Compliance; Random Allocation; Rimantadine | 1986 |
Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults.
Topics: Adamantane; Administration, Oral; Adult; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Influenza A virus; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Nasal Mucosa; Random Allocation; Rimantadine | 1986 |
A comparison of acetaminophen and rimantadine in the treatment of influenza A infection in children.
Topics: Acetaminophen; Adamantane; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Humans; Infant; Influenza A virus; Influenza, Human; Random Allocation; Rimantadine | 1987 |
73 other study(ies) available for adamantane and Grippe
Article | Year |
---|---|
X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance.
Topics: Adamantane; Amines; Antiviral Agents; Binding Sites; Crystallography, X-Ray; Drug Resistance, Bacterial; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Ligands; Molecular Dynamics Simulation; Mutation; Radiography; Viral Matrix Proteins | 2020 |
[Assessment of the antiviral activity of 2HCl*H-His-Rim compound compared to the anti-influenza drug Arbidol for influenza caused by A/duck/Novosibirsk/56/05 (H5N1) (Influenza A virus, Alphainfluenzavirus, Orthomyxoviridae).]
Topics: Adamantane; Animals; Antiviral Agents; Chlorocebus aethiops; Drug Resistance, Viral; Ducks; Humans; Indoles; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Microbial Sensitivity Tests; Vero Cells; Viral Load; Virus Replication | 2019 |
Influenza A M2 Inhibitor Binding Understood through Mechanisms of Excess Proton Stabilization and Channel Dynamics.
Topics: Adamantane; Amino Acid Sequence; Antiviral Agents; Binding Sites; Drug Design; Humans; Influenza A virus; Influenza, Human; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Protons; Viral Matrix Proteins | 2020 |
Distribution and evolution of H1N1 influenza A viruses with adamantanes-resistant mutations worldwide from 1918 to 2019.
Topics: Adamantane; Animals; Antiviral Agents; Drug Resistance, Viral; Europe; Evolution, Molecular; Host Specificity; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; North America; Orthomyxoviridae Infections; Phylogeny; Swine; Viral Proteins | 2021 |
Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Australia; Drug Resistance, Viral; Genome, Viral; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Phylogeny; RNA, Viral; Seasons; Sequence Analysis, DNA | 2017 |
Adamantane and neuraminidase inhibitor resistance among circulating human influenza A viruses in Cuba during 2006-2010.
Topics: Adamantane; Antiviral Agents; Cuba; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A virus; Influenza, Human; Molecular Sequence Data; Mutation, Missense; Neuraminidase; RNA, Viral; Sequence Analysis, DNA | 2013 |
Comparative dynamics and distribution of influenza drug resistance acquisition to protein m2 and neuraminidase inhibitors.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Genome, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Phylogeny; United States; United States Food and Drug Administration; Viral Matrix Proteins | 2014 |
Adamantane-resistant influenza a viruses in the world (1902-2013): frequency and distribution of M2 gene mutations.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Mutation; Viral Matrix Proteins | 2015 |
Determining drug efficacy parameters for mathematical models of influenza.
Topics: Adamantane; Antiviral Agents; Biological Assay; Enzyme Inhibitors; Humans; Influenza, Human; Models, Biological; Neuraminidase; Treatment Outcome | 2015 |
An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses.
Topics: Adamantane; Amantadine; Animals; Antiviral Agents; Dogs; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Inhibitory Concentration 50; Madin Darby Canine Kidney Cells; Molecular Dynamics Simulation; Mutation; Orthomyxoviridae Infections; Spiro Compounds; Structure-Activity Relationship; Viral Matrix Proteins | 2017 |
Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries.
Topics: Adamantane; Animals; Antiviral Agents; Asia, Southeastern; Australia; Cell Line; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Phylogeny; Viral Proteins | 2008 |
Control of an outbreak due to an adamantane-resistant strain of influenza A (H3N2) in a chronic care facility.
Topics: Adamantane; Adolescent; Adult; Child; Child, Preschool; Disease Outbreaks; Drug Resistance, Viral; Female; Humans; Infection Control; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Mutation; Nursing Homes; Retrospective Studies; Young Adult | 2008 |
Evolution of drug resistance in multiple distinct lineages of H5N1 avian influenza.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Evolution, Molecular; Genome, Viral; Genotype; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Phylogeny; Reassortant Viruses; Selection, Genetic; Viral Matrix Proteins | 2009 |
Human influenza A viruses isolated in South America: genetic relations, adamantane resistance and vaccine strain match.
Topics: Adamantane; Amino Acid Sequence; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Molecular Epidemiology; Molecular Sequence Data; Phylogeny; Uruguay | 2009 |
Influenza antiviral resistance testing in new york and wisconsin, 2006 to 2008: methodology and surveillance data.
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; New York; RNA, Viral; Sequence Analysis, DNA; Viral Proteins; Wisconsin | 2009 |
Influenza virus resistance to antiviral agents: a plea for rational use.
Topics: Adamantane; Animals; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza, Human; Oseltamivir | 2009 |
The origin and global emergence of adamantane resistant A/H3N2 influenza viruses.
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Phylogeny; Sequence Analysis, DNA; Viral Matrix Proteins | 2009 |
Perspectives on influenza virus infection.
Topics: Adamantane; Adolescent; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase | 2009 |
Rapid spread of drug-resistant influenza A viruses in the Basque Country, northern Spain, 2000-1 to 2008-9.
Topics: Adamantane; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation; Oseltamivir; Spain | 2009 |
Susceptibility of antiviral drugs against 2009 influenza A (H1N1) virus.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Viral Matrix Proteins | 2009 |
Antiviral resistance in influenza viruses circulating in Central and South America based on the detection of established genetic markers.
Topics: Adamantane; Amino Acid Sequence; Animals; Antiviral Agents; Cell Line; Central America; Dogs; Drug Resistance, Viral; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Molecular Sequence Data; Neuraminidase; Orthomyxoviridae; Oseltamivir; Sequence Alignment; South America; Viral Matrix Proteins | 2009 |
Extrapolating from sequence--the 2009 H1N1 'swine' influenza virus.
Topics: Adamantane; Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Consensus Sequence; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Polysaccharides; Protein Binding; RNA-Dependent RNA Polymerase; Sequence Analysis, Protein; Viral Matrix Proteins; Viral Proteins | 2009 |
Dynamics of antiviral-resistant influenza viruses in the Netherlands, 2005-2008.
Topics: Adamantane; Antiviral Agents; Cluster Analysis; Drug Resistance, Viral; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Netherlands; Phylogeny; RNA, Viral; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
Genomic events underlying the changes in adamantane resistance among influenza A(H3N2) viruses during 2006-2008.
Topics: Adamantane; Antiviral Agents; Cluster Analysis; Drug Resistance, Viral; Genome, Viral; Genotype; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Phylogeny; RNA, Viral; Sequence Analysis, DNA; Sequence Homology | 2009 |
Safety of oseltamivir compared with the adamantanes in children less than 12 months of age.
Topics: Adamantane; Antiviral Agents; Central Nervous System; Female; Humans; Infant; Infant, Newborn; Influenza, Human; Male; Nervous System Diseases; Oseltamivir; Retrospective Studies; Rimantadine | 2010 |
Antiviral prescriptions to U.S. ambulatory care visits with a diagnosis of influenza before and after high level of adamantane resistance 2005-06 season.
Topics: Adamantane; Adolescent; Adult; Ambulatory Care; Antiviral Agents; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Infant, Newborn; Influenza, Human; Male; Middle Aged; Seasons; United States; Young Adult | 2010 |
Double (V27A/S31N) mutant 2009 pandemic influenza A (H1N1) virus isolated from adamantane non-treated inmunocompetent child.
Topics: Adamantane; Adolescent; Amino Acid Substitution; Antiviral Agents; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation, Missense; Spain; Viral Matrix Proteins | 2010 |
Influenza antiviral prescribing practices during the 2007-08 and 2008-09 influenza seasons in the setting of increased resistance to oseltamivir among circulating influenza viruses.
Topics: Adamantane; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Drug Utilization; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Rimantadine; Seasons; Surveys and Questionnaires; Zanamivir | 2010 |
Influence of an additional amino group on the potency of aminoadamantanes against influenza virus A. II - Synthesis of spiropiperazines and in vitro activity against influenza A H3N2 virus.
Topics: Adamantane; Animals; Antiviral Agents; Cell Line; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Orthomyxoviridae Infections; Piperazines; Spiro Compounds | 2010 |
Emerging influenza antiviral resistance threats.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Multiple, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation, Missense; Oseltamivir; Reassortant Viruses; Virus Replication | 2011 |
Dual resistance to adamantanes and oseltamivir among seasonal influenza A(H1N1) viruses: 2008-2010.
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Drug Resistance, Multiple, Viral; Genome, Viral; Genotype; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation, Missense; Neuraminidase; Oseltamivir; RNA, Viral; Viral Matrix Proteins; Viral Proteins | 2011 |
Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro.
Topics: Acids, Carbocyclic; Adamantane; Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Cyclopentanes; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oseltamivir; Pyrans; Pyrrolidines; Sialic Acids; Viral Plaque Assay; Zanamivir | 2010 |
Antiviral drugs for influenza.
Topics: Adamantane; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase | 2011 |
Oseltamivir-resistant pandemic (H1N1) 2009 virus, Mexico.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mexico; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Pandemics; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; Zanamivir | 2011 |
Adamantane- and oseltamivir-resistant seasonal A (H1N1) and pandemic A (H1N1) 2009 influenza viruses in Guangdong, China, during 2008 and 2009.
Topics: Adamantane; China; Cluster Analysis; Drug Resistance, Viral; Genotype; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Molecular Sequence Data; Neuraminidase; Oseltamivir; Sequence Analysis, DNA; Viral Matrix Proteins; Viral Proteins | 2011 |
[Influenza : clinical symptoms, diagnostics and therapy].
Topics: Adamantane; Adult; Age Factors; Aged; AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Female; Germany; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Neuraminidase; Pandemics; Pneumonia, Viral; Population Surveillance; Pregnancy; Rimantadine; Survival Rate | 2011 |
H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Binding Sites; Crystallography, X-Ray; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Pandemics; Protein Conformation; Zanamivir | 2012 |
Spiro[pyrrolidine-2,2'-adamantanes]: synthesis, anti-influenza virus activity and conformational properties.
Topics: Adamantane; Antiviral Agents; Cell Line; Humans; Influenza A virus; Influenza, Human; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Pyrrolidines; Structure-Activity Relationship | 2003 |
[Treatment of influenza in children].
Topics: Adamantane; Amantadine; Antiviral Agents; Child; Guanidines; Humans; Influenza, Human; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2003 |
Resistance to anti-influenza agents.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A virus; Influenza Vaccines; Influenza, Human | 2005 |
High levels of adamantane resistance among influenza A (H3N2) viruses and interim guidelines for use of antiviral agents--United States, 2005-06 influenza season.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Practice Guidelines as Topic; Seasons; United States | 2006 |
Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States.
Topics: Adamantane; Antiviral Agents; Biological Assay; Drug Resistance, Viral; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Mutation; Seasons; Sequence Analysis; United States; Viral Matrix Proteins | 2006 |
Adamantane resistance in influenza A.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Viral Matrix Proteins | 2006 |
Influenza-associated deaths among children.
Topics: Acetamides; Adamantane; Antiviral Agents; Child; Humans; Influenza, Human; Oseltamivir; United States | 2006 |
Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005.
Topics: Adamantane; Antiviral Agents; Australia; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Phylogeny; Rimantadine; Zanamivir | 2007 |
Shift shown in influenza A adamantane resistance.
Topics: Adamantane; Alzheimer Disease; Antiviral Agents; Drug Resistance, Viral; Excitatory Amino Acid Antagonists; Humans; Influenza A virus; Influenza, Human; Memantine | 2006 |
Shift shown in influenza A adamantane resistance.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Neuraminidase | 2006 |
Drug resistance among influenza A viruses isolated in Italy from 2000 to 2005: are the emergence of Adamantane-resistant viruses cause of concern?
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Italy; Neuraminidase | 2006 |
The emergence of adamantane resistance in influenza A(H1) viruses in Australia and regionally in 2006.
Topics: Adamantane; Adolescent; Adult; Aged; Amino Acid Substitution; Antiviral Agents; Asia, Eastern; Asia, Southeastern; Australia; Child; Child, Preschool; Drug Resistance, Viral; Genotype; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Middle Aged; Pacific Islands; Prevalence; Rimantadine; South Africa | 2007 |
The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance.
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Asia; Australia; Biological Assay; Drug Resistance, Viral; Evolution, Molecular; Genetic Variation; Genome, Viral; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Japan; New Zealand; Phylogeny; United States; Viral Matrix Proteins | 2007 |
Pandemic flu vaccine: are we doing enough?
Topics: Adamantane; Adjuvants, Immunologic; Animals; Antiviral Agents; Disease Outbreaks; Drug Approval; Drug Design; Drug Resistance, Viral; Enzyme Inhibitors; History, 20th Century; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Poultry; United States; United States Food and Drug Administration | 2007 |
Adamantane-resistant influenza infection during the 2004-05 season.
Topics: Adamantane; Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Cohort Studies; Disease Outbreaks; Drug Resistance, Viral; Female; Humans; Infant; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Male; Middle Aged; Wisconsin | 2008 |
Adamantane resistance in circulating human influenza A viruses from Alberta, Canada (1970-2007).
Topics: Adamantane; Alberta; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Mutation, Missense; Time Factors; Viral Matrix Proteins | 2008 |
Emergence of adamantane-resistant influenza A(H3N2) viruses in Hong Kong between 1997 and 2006.
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Drug Utilization Review; Hong Kong; Humans; Infant; Influenza A Virus, H3N2 Subtype; Influenza, Human; Molecular Sequence Data; Mutation, Missense; RNA, Viral; Sequence Analysis, DNA; Viral Matrix Proteins | 2008 |
[Combined prevention of influenza using inactivated influenza vaccine and remantadine in organized collectives of adults].
Topics: Adamantane; Adult; Disease Outbreaks; Drug Evaluation; Humans; Influenza Vaccines; Influenza, Human; Rimantadine; Russia; Vaccines, Attenuated | 1982 |
[Organization and evaluation of the effectiveness of emergency prophylaxis and early treatment of influenza with remantadine in Serevodvinsk].
Topics: Adamantane; Adult; Drug Evaluation; Emergencies; Epidemiologic Methods; Humans; Influenza, Human; Rimantadine; Russia; Time Factors; Urban Population | 1983 |
[Efficacy of remantadin in influenza B].
Topics: Adamantane; Adult; Humans; Influenza, Human; Orthomyxoviridae; Rimantadine; Russia; Serotyping | 1983 |
[Effectiveness of remantadine in outpatients during a period of epidemic outbreaks of influenza A and B].
Topics: Absenteeism; Adamantane; Ambulatory Care; Disease Outbreaks; Drug Evaluation; Humans; Influenza, Human; Rimantadine; Russia; Urban Population | 1984 |
[New organized approach to rendering medical services to patients during influenza outbreak].
Topics: Adamantane; Antiviral Agents; Disease Outbreaks; Humans; Influenza A virus; Influenza, Human; Rimantadine; Russia | 1984 |
[Emergency prevention of influenza with remantadine].
Topics: Adamantane; Adolescent; Adult; Disease Outbreaks; Humans; Influenza, Human; Rimantadine; USSR | 1984 |
[Amantadine and riamantadine in the treatment of influenza].
Topics: Adamantane; Amantadine; Humans; Influenza, Human; Rimantadine | 1983 |
[Emergency prevention of influenza with remantadin].
Topics: Adamantane; Adolescent; Adult; Disease Outbreaks; Drug Evaluation; Female; Humans; Influenza Vaccines; Influenza, Human; Male; Placebos; Rimantadine; USSR | 1982 |
[Therapeutic effectiveness of rimantadine and antigrippen against A1(H1N1) influenza in the 1977-1978 epidemic].
Topics: Adamantane; Adult; Ascorbic Acid; Aspirin; Diphenhydramine; Drug Combinations; Evaluation Studies as Topic; Humans; Influenza, Human; Lactates; Rimantadine; Rutin; USSR | 1981 |
[Experience with clinical trials of the new anti-influenza drug rimantadine].
Topics: Adamantane; Antiviral Agents; Ascorbic Acid; Aspirin; Diphenhydramine; Drug Combinations; Humans; Influenza, Human; Lactates; Retrospective Studies; Rimantadine; Rutin | 1981 |
[Clinical use of the anti-influenza preparation rimantadine].
Topics: Adamantane; Humans; Influenza A virus; Influenza, Human; Rimantadine | 1981 |
Comparison of amantadine and rimantadine for prevention of type A (Russian) influenza.
Topics: Adamantane; Adolescent; Adult; Age Factors; Amantadine; Antibodies, Viral; Double-Blind Method; Drug Evaluation; Female; Humans; Influenza A virus; Influenza, Human; Male; Rimantadine | 1981 |
[Prevention of pneumonia in influenza A by means of a new anti-influenza drug rimantadine].
Topics: Adamantane; Adult; Humans; Influenza A virus; Influenza, Human; Middle Aged; Pneumonia, Viral | 1980 |
[Treatment of patients with influenza].
Topics: Adamantane; Adolescent; Adult; Aged; Codeine; Critical Care; Dipyrone; Drug Evaluation; Ephedrine; gamma-Globulins; Gossypol; Humans; Imidazoles; Influenza, Human; Interferons; Lactoglobulins; Middle Aged; Naphthoquinones; Oxygen Inhalation Therapy; Sympathomimetics; Time Factors | 1975 |
[Chemotherapy of virus diseases].
Topics: Adamantane; Cytarabine; Humans; Idoxuridine; Influenza, Human; Interferons; Vidarabine; Virus Diseases | 1978 |
Rimantadine and seizures.
Topics: Adamantane; Adult; Aged; Aged, 80 and over; Anticonvulsants; Humans; Influenza, Human; Male; Rimantadine; Seizures | 1989 |
Resistance of influenza A virus to amantadine and rimantadine: results of one decade of surveillance.
Topics: Adamantane; Amantadine; Animals; Antigens, Viral; Cell Line; Cytopathogenic Effect, Viral; Dogs; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Humans; Influenza A virus; Influenza, Human; Rimantadine; Viral Plaque Assay | 1989 |
[Principles of the use of anti-influenza drugs].
Topics: Adamantane; Ambulatory Care; Disease Outbreaks; Drug Administration Schedule; Humans; Influenza, Human; Rimantadine; Russia | 1988 |
Current status of amantadine and rimantadine as anti-influenza-A agents: memorandum from a WHO meeting.
Topics: Adamantane; Amantadine; Humans; Influenza A virus; Influenza, Human; Rimantadine | 1985 |